СПОСОБ ДЕГИДРОФТОРИРОВАНИЯ АРОМАТИЧЕСКОГО КАРБАМИЛФТОРИДА

Изобретение относится к способу дегидрофторирования, который позволяет перейти от ароматического карбамилфторида к соответствующему изоцианату. Способ заключается в том, что вышеупомянутый карбамилфторид подвергают воздействию температуры, по меньшей мере равной 80°С, и самое большое равной 150°С, в растворителе, в том, что при вышеупомянутой температуре по меньшей мере 80°С вышеупомянутый карбамилфторид находится в растворителе в растворенном или тонкодиспергированном состоянии, и в том, что этот растворитель выбран из растворителей, способных смешиваться с фтористоводородной кислотой и имеющих температуру кипения по меньшей мере 100°С. 14 з.п. ф-лы, 1 табл.

СПОСОБ ПОЛУЧЕНИЯ СМЕСИ ПОЛИФЕНИЛЕНПОЛИМЕТИЛЕНПОЛИИЗОЦИАНАТОВ

Использование: в производстве замещенных изоцианатов, в частности в способе получения полифениленполиметиленполиизоцианатов. Сущность изобретения: продукт - смесь полифениленполиметиленполизоцианатов. Реагент 1: изоцианатокарбамоилхлорид, полученный при конденсации анилина с формалином с последующим фосгенированием. Реагент 2: фенилизоцианат в количестве 1 - 3 моль на 1 моль формалина. Условия реакции: нагревание при 150 - 170С в присутствии катализатора - хлоридов аммония, цинка, железа, олова, взятых в количестве 1 - 3 мас. % от массы реакционной смеси. 2 табл.

Способ получения алкилизоцианатов

FIELD: chemistry. SUBSTANCE: invention relates to the method of producing alkylisocyanates of the general formula I R-N=C=O, where R is an alkyl group of normal, branched, or cyclic structure with the carbon number of 1 to 8. The method consists in carrying out thermolysis at 200-450°C at the top of the column in the continuous feeding of the corresponding O-(2-hydroxyethyl)carbamate and an inert gas carrier to the top of the column followed by the fractional condensation of the resulting target and by-products. EFFECT: method allows to obtain alkylisocyanates of the general formula I with a high yield. 1 dwg, 9 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 655 386 C1 (51) МПК C07C 263/04 (2006.01) C07C 265/04 (2006.01) C07C 265/10 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК C07C 263/04 (2006.01) (21)(22) Заявка: 2017117481, 19.05.2017 (24) Дата начала отсчета срока действия патента: Дата регистрации: 28.05.2018 (45) Опубликовано: 28.05.2018 Бюл. № 16 2 6 5 5 3 8 6 R U (54) Способ получения алкилизоцианатов (57) Реферат: Изобретение относится к способу получения алкилизоцианатов общей формулы I, где R алкильные группы нормального, разветвленного или циклического строения с числом атомов углерода от 1 до 8. Способ заключается в том, что в насадочной колонне при непрерывной подаче соответствующего O-(2-гидроксиэтил) карбамата и инертного газа-носителя в верхнюю часть колонны осуществляют термолиз при 200- Стр.: 1 (56) Список документов, цитированных в отчете о поиске: US 3076007, 29.01.1963. US 2011/ 0092731 A1, 21.04.2011. SU 1836336 A3, 23.08.1993. 450°C с последующей фракционной конденсацией полученных целевого и побочного продуктов. Предлагаемый способ позволяет получать алкилизоцианаты общей формулы I с высоким выходом. 1 ил., 9 пр. C 1 C 1 Адрес для переписки: 125047, Москва, Миусская пл., 9, Российский химико-технологический университет имени Д.И. Менделеева, патентно-лицензионный отдел (73) ...

Способ получения алкилизоцианата

1-MONOHALOGENIERTE ISOCYANATE UND VERFAHREN ZUR HERSTELLUNG VON GEMISCHEN VON 1-MONOHALOGENIERTEN ISOCYANATEN UND 1,2-UNGESAETTIGTEN ISOCYANATEN

VERFAHREN ZUR HERSTELLUNG VON AROMATISCHEN ISOCYANATEN

PROCESS FOR PREPARING ARYL ISOCYANATES BY THERMAL DECOMPOSITION OF ARYL URETHANES

Verfahren zur Herstellung von Diurethanen und ihre Verwendung zur Herstellung von Diisocyanaten

PROCESS FOR THE PREPARATION OF URETHANES

Organic Isocyanates and a Process for the Production thereof

... 1,156,378. Organic isocyanate derivatives of carbamates. FARBENFABRIKEN BAYER A.G. 10 Nov., 1967 [30 Nov., 1966], No. 51192/67. Heading C2C. N - Substituted - N - isocyanato methyl carbamic and thiocarbamic acid esters of the formula wherein R represents a branched or unbranched, saturated or unsaturated, aliphatic, cycloaliphatic or araliphatic radical with 1 to 12 carbon atoms, optionally substituted by a chlorine atom or cyano radical, X represents oxygen or sulphur, R1 represents a branched or unbranched, saturated or unsaturated aliphatic, cycloaliphatic, araliphatic or aromatic, monovalent or divalent radical with 1-15 carbon atoms, optionally substituted by a chlorine atom or cyano radical, and n is 1 or 2, may be obtained by reacting an N-substituted-N- chloromethyl carbamic or thiocarbamic acid ester of the formula with an alkali or alkaline earth metal cyanate at a temperature of 30-230‹ C. in the presence of an inert solvent. Suitable solvents in which the reaction may ...

PROCESS FOR THE PRODUCTION OF ISOCYANATES

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

REACTOR FOR THERMAL SPLITTING OF MONO ONES AND POLYFUNCTIONAL ONES CARBAMIDS UREESTERN

PROCEDURE FOR THE PRODUCTION OF ISOCYANATES

PROCEDURE FOR THERMAL SPLITTING OF CARBAMIDSÄUREESTERN

INTEGRATED PROCEDURE FOR THE PRODUCTION OF AROMATIC ISOCYANATES AND PROCEDURE FOR THE PRODUCTION OF THE INTERMEDIATES PHASE

CYCLE PROCEDURE FOR THE PRODUCTION OF (CYCLO) ALIPHATIC DIISOCYANATEN.

PROCEDURES FOR THE PRODUCTION OF ORGANIC DIURETHANEN AND/OR PU AND YOUR USE DI FOR THE PRODUCTION OF AND/OR POLYISOCYANATEN

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

MULTI-LEVEL PROCEDURE FOR THE CONTINUOUS PRODUCTION OF CYCLO-ALIPHATIC DIISOCYANATEN

HETEROGENEOUS SUPPORTED CATALYTIC CARBAMATE PROCESS

A process for the preparation of aromatic carbamates comprising contacting one or more organic carbonates with an aromatic amine or urea in the presence of a catalyst and recovering the resulting aromatic carbamate product, characterized in that the catalyst is a heterogeneous catalyst comprising a Group 12-15 metal compound supported on a substrate.

PROCESS FOR PREPARATION OF AROMATIC ISOCYANATES

A PROCESS FOR PREPARATION OF AROMATIC ISOCYANATES A process is described for preparing aromatic isocyanates by contacting an aromatic carbamate of the formula R(NHCO2R')n at 150-350.degree.C under reduced pressure with one or more metal or metal compound catalysts dissolved in an inert solvent. In the formula R is a divalent aromatic, R' is a monovalent aliphatic, alicyclic or aromatic with at most 8 carbon atoms and n is 1 or 2. The metal is dissolved in a concentration of at least 1/1000% by weight of the solvent. The vapors of the resulting aromatic isocyanate and alcohol or phenol are fractionally condensed under reduced pressure and the aromatic isocyanate is separately collected.

PREPARATION OF A NOVEL DIISOCYANATE FROM NORBORNADIENE

PREPARATION OF A NOVEL DIISOCYANATE FROM NORBORNADIENE Novel bicyclic alkyl dicarbamates are prepared from norbornadiene and other simple starting materials, and these are subsequently thermally cracked to novel diisocyanate norbornyl derivatives, which are, among others, useful for crosslinking active hydrogen compounds.

PROCESS FOR THE PRODUCTION OF N,O-DISUBSTITUTED URETHANES

Mo-2276 LeA 20,586 A PROCESS FOR THE PRODUCTION OF N,O-DISUBSTITUTED URETHANES N,O-disubstituted urethanes are produced by reacting a primary amine with a dialkyl carbonate in the presence of a catalyst. Suitable catalysts include neutral and basic compounds of lead, titanium and zirconium. The urethanation reaction is desirably carried out at a temperature in the range of 80 to 250.degree.C. The N,O-disubstituted urethanes produced by this process are particularly useful as starting materials in processes for the production of isocyanates. LeA 20,586 ...

TERTIARY ARALKYL URETHANES AND ISOCYANATES DERIVED THEREFROM

TERTIARY ARALKYL URETHANES AND ISOCYANATES DERIVED THEREFROM Production of tertiary aralkyl isocyanates, such as tetramethyl xylylene diisocyanates, by thermal cracking of corresponding olefins and carbamic acid esters at moderate temperatures and in the presence of acid catalyst.

RECOVERY OF SOLVENTS EMPLOYED IN THE UCTION OF ISOCYANATES FROM ESTERS OF AMIC ACIDS (URETHANES)

METHOD FOR PREPARING HALOSILYL CARBAMATES AND ISOCYANATES DERIVED THEREFROM

A PROCESS FOR THE PREPARATION OF HIGHLY PURE AROMATIC DIURETHANES AND/OR POLYURETHANES

Mo3814 LeA 28,779 A PROCESS FOR THE PREPARATION OF HIGHLY PURE AROMATIC DIURETHANES AND/OR POLYURETHANES This invention relates to a process for the preparation of highly pure aromatic diurethanes and/or polyurethanes by reaction of the corresponding aromatic diamines and/or polyamines with unsubstituted carbamates with the release of ammonia. The reaction is carried out in the presence of excess carbamates. The resultant reaction mixture is freed from any solvents used, and the formed aromatic diurethanes and/or polyurethanes are purified by extraction with water.

A PROCESS FOR THE PREPARATION OF POLYISOCYANATES

A PROCESS FOR THE PREPARATION OF POLYISOCYANATES The present invention relates to a process for the preparation of a polyisocyanate comprising (a) thermally decomposing in a tube reactor a solution of an N-substantially carbamic acid ester corresponding to said polyisocyanate in a solvent used as decomposition medium, wherein said solvent (i) is capable of dissolving the carbamic acid ester, (ii) is stable at the decomposition temperature and chemically inert towards the carbamic acid esters and the polyisocyanate product, (iii) can be distilled without decomposing under the conditions of decomposition of carbamic acid esters, and (iv) has at least one miscibility gap with an extracting agent used according to the extraction step (c), said solutions being carried along the internal wall of reactor; (b) separating the gaseous materials formed in the tube reactor by fractional condensation into a fraction I comprised mainly of the alcohol by-product and a fraction II comprised mainly of polyisocyanates ...

PROCESS FOR PREPARING ISOCYANATES

Multistep, Continuous Preparation of Organic Polyisocyanates

A PROCESS FOR THE PRODUCTION OF POLYISOCYANATES

Mo3804 LeA 28,719 A PROCESS FOR THE PRODUCTION OF POLYISOCYANATES A process for the continuous catalyst-free production of polyisocyanates by thermal decomposition of the N-substituted carbamic acid esters corresponding to the polyisocyanates, in which the carbamic acid esters to be decomposed, in the form of a 5 to 90% by weight solution in an inert high-boiling solvent, are heated to a temperature of 100 to 400.degree.C and are subsequently introduced with expansion as a sidestream into a distillation column (4), in the sump of which a pressure of 0.001 to 5 bar and a temperature of 150 to 400.degree.C are maintained so that the high boiler is kept boiling in the sump, and the decomposition products are simultaneously condensed continuously and selectively at the head of the distillation column. The high boiler which optionally contains impurities, is continuously removed via the sump outlet in a quantity substantially corresponding to the quantity of high boiler introduced into the column ...

Procédé de préparation d'isocyanates organiques.

Verfahren zur Herstellung von Isocyanaten

Verfahren zur Herstellung von organischen Isocyanaten

Verfahren zur Herstellung von Isocyanaten

PROCEDE DE PREPARATION D' iSOCYANATE.

PROCEDURE FOR THE PRODUCTION OF MONO ISOCYANATES.

Process for preparing organic isocyanates

Organic isocyanates are prepared by reacting primary amines and carbon dioxide with hexamethyldisilazane in the presence of an acidic catalyst at a temperature of 40 to 200 DEG C and decomposing the silyl carbamate which is formed in the presence of a dehydrating agent at a temperature of 0 to 350 DEG C. The desired product is obtained with a yield of 84 to 97% and with a content of main compound of up to 99.9%. No enviromentally polluting substances are formed in the above process.

Process for preparing alkyl isocyanates

PROCEDURE FOR THE PRODUCTION OF ALIPHATIC MONO ISOCYANATES.

PROCEDURE FOR THE PRODUCTION OF ISOCYANATES.

СПОСОБ ПОЛУЧЕНИЯ СЛОЖНОГО ЭФИРА N-ЗАМЕЩЕННОЙ КАРБАМИНОВОЙ КИСЛОТЫ, СПОСОБ ПОЛУЧЕНИЯ ИЗОЦИАНАТА С ПРИМЕНЕНИЕМ ТАКОГО СЛОЖНОГО ЭФИРА N-ЗАМЕЩЕННОЙ КАРБАМИНОВОЙ КИСЛОТЫ И КОМПОЗИЦИЯ ДЛЯ ТРАНСПОРТИРОВКИ И ХРАНЕНИЯ СЛОЖНОГО ЭФИРА N-ЗАМЕЩЕННОЙ КАРБАМИНОВОЙ КИСЛОТЫ, СОДЕРЖАЩАЯ СЛОЖНЫЙ ЭФИР N-ЗАМЕЩЕННОЙ КАРБАМИНОВОЙ КИСЛОТЫ И АРОМАТИЧЕСКОЕ ГИДРОКСИСОЕДИНЕНИЕ

Данное изобретение представляет собой способ получения сложного эфира N-замещенной карбаминовой кислоты, получаемого из органического амина, производного угольной кислоты и гидроксикомпозииии, содержащей один или несколько видов гидроксисоединений, в котором органический амин, производное угольной кислоты и гидроксикомпозиция реагируют с применением реакционного резервуара для получения уретана, снабженного конденсатором, газ, содержащий гидроксикомпозицию, соединение, имеющее карбонильную группу, полученное из производного угольной кислоты, и аммиак, образованный в качестве побочного продукта в ходе реакционного взаимодействия, вводится в конденсатор, предусмотренный в реакционном резервуаре для получения уретана, и гидроксикомпозиция и соединение, имеющее карбонильную группу, полученное из производного угольной кислоты, конденсируются, и в котором гидроксисоединение, содержащееся в сконденсированной гидроксикомпозиции, содержится, в расчете на стехиометрическое соотношение, в количестве ...

METHOD OF PREPARING ESTER N-SUBSTITUTED CARBAMIC ACID, USING SUCH A METHOD OF PRODUCING ISOCYANATE ESTER N-SUBSTITUTED CARBAMIC ACID AND COMPOSITION FOR TRANSPORTATION AND STORAGE OF ESTER N-SUBSTITUTED CARBAMIC ACID, CONTAINING ESTER OF N-SUBSTITUTED CARBAMIC ACID AND AROMATIC HYDRO KSISOEDINENIE

Separation method, and method for producing isocyanates

PROCESS FOR THE SYNTHESIS OF ISOCYANATES WITH CARBAMATES HALOSILYLE

CARBAMATES HALOSILYLE AND THEIR PROCESS USING ISOCYANATES

PROCEDE DE FABRICATION D'ISOCYANATES D'ALKYLE

L'invention concerne un procédé de fabrication d'isocyanates d'alkyle comportant au moins 3 atomes de carbone. Selon l'invention on décompose le chlorure de N-alkyle carbamyle correspondant entre - 20 et + 15 degrés C, de préférence entre -10 et + 5 degrés C, en la seule présence d'une solution aqueuse de base minérale et d'une agitation modérée. De préférence on utilise de la soude ou de la potasse en excès de 5 à 15 % par rapport à la stoechiométrie. On évite notamment le séchage de l'isocyanate formé et la purification de ce dernier est simplifiée. Application : fabrication d'isocyanates d'alkyle utiles comme intermédiaires de synthèse.

MANUFACTURE OF ALIPHATIC ISOCYANATES

PRODUCTION OF ISOCYANATES

CARBAMATES HALOSILYLE AND THEIR PROCESS USING ISOCYANATES

PROCESS FOR THE PRODUCTION OF 1-ALKENYL ISOCYANATES

PROCESS OF PRODUCTION Of ISOCYANATES STARTING FROM ESTERS Of CARBAMIC ACIDS AROMATIC

METHOD FOR PRODUCING CARBAMATE, METHOD FOR PRODUCING ISOCYANATE, CARBAMATE PRODUCTION SYSTEM, AND ISOCYANATE PRODUCTION SYSTEM

PROCESS FOR THE PREPARATION OF ISOCYANATES

The invention relates to a multistage process for the continuous preparation of organic, distillable polyisocyanates, preferably of diisocyanates, particularly preferably of aliphatic or cycloaliphatic diisocyanates, by reacting the corresponding organic polyamines with carbonic acid derivatives and alcohols in low molecular weight monomeric polyurethanes and their thermal cleavage, in which, at certain stages in the reaction, the prepared polyisocyanates and unutilizable residues are separated off and reusable by-products and intermediate products are returned to initial stages.

METHOD FOR PRODUCING 1,5-PENTAMETHYLENE DIAMINE, 1,5-PENTAMETHYLENE DIAMINE, 1,5-PENTAMETHYLENE DIISOCYANATE, METHOD FOR PRODUCING 1,5-PENTAMETHYLENE DIISOCYANATE, POLYISOCYANATE COMPOSITION, AND POLYURETHANE RESIN

Disclosed is a method for producing 1,5-pentamethylene diamine, wherein a processed lysine decarboxylase expressing microorganism is used.

Process for the synthesis of aromatic carbamates

The present invention discloses a process for the synthesis of aromatic carbamates from amine with dialkyl carbonate in the presence of binary or ternary mixed metal oxide catalyst. The present invention further discloses the yield of said aromatic carbamate in the range of 60 to 99%. Further, the ratio of amine to dialkyl carbonate is in the range of 1:2 to 1:30.

Method for producing mdi, especially 2,4'-mdi

MDI is prepared by a process comprising the following steps: A) reaction of aniline and formaldehyde in the presence of an acid to give methylene(diphenyldiamines) and polymethylenepolyphenylenepolyamines, the molar ratio of acid to amine being not more than 0.2, B) reaction of the mixture obtained in step A) with phosgene to give methylene(diphenyl diisocyanates) and polymethylenepolyphenylene polyisocyanates, C) separation of the mixture obtained in step B) into monomeric MDI and polymeric MDI and D) separation of the monomeric MDI obtained in step C) by isolating 2,4′-MDI.

Process for preparing isocyanates

A process for preparing isocyanates comprising contacting carbon dioxide and a primary amine in the presence of an aprotic organic solvent and a base selected from the group consisting of a phosphazene compound, an organic, nitrogenous base and mixtures thereof, wherein the organic, nitrogenous base selected from the group consisting of guanidine compounds, amidine compounds, tertiary amines and mixtures thereof to produce the corresponding ammonium carbamate salt, reacting the ammonium carbamate salt with an anhydride dehydrating agent to produce a product stream comprising the corresponding isocyanate, the aprotic organic solvent and the base salt derived from the anhydride, separating the base salt from the product stream, recovering and recycling the base, and regenerating and recycling the anhydride dehydrating agent.

Manufacture of aliphatic isocyanates

A process for the manufacture of aliphatic isocyanates by thermal decomposition of aliphatic carbamic acid halides. The decomposition is carried out in stages and the hydrogen halide liberated is expelled, in the first stage, without passing inert gas through the reaction mixture, while in the second stage it is expelled while passing an inert gas, which is recycled, through the reaction mixture.

Method for producing carbamates and method for producing isocyanates

A method for producing carbamates that enables carbamates to be produced at low costs, with high selectivity and high yield, and in a simple manner, and a method for producing isocyanates that enables isocyanates industrially used to be produced by using the carbamates obtained by the carbamates producing method. Nonaromatic amine selected from the group consisting of aliphatic amine, alicyclic amine, and aralkyl amine is allowed to react with alkylaryl carbonate to thereby produce carbamates. Also, the carbamates thus obtained are thermally decomposed to thereby produce isocyanates. When carbamates are produced in this method, alkyl carbamates can be obtained with high selectivity and at high yield by using simple equipment. Also, when isocyanates are produced in this method, polyisocyanates used industrially as the raw material of polyurethane can be produced in a simple manner and with efficiency.

Process for preparing aromatic carbamates

The invention is directed to a process for preparing aromatic carbamates which comprises the reaction of an aromatic amine with an organic carbonate in the presence of a catalyst characterized in that Zn4O(OAc)6 is used as catalyst.

PROCESS FOR THE PREPARATION OF ORGANIC POLYISOCYANATES

PROCESS FOR PREPARING AROMATIC CARBAMATES

ONE-POT PRODUCTION OF CARBAMATES USING SOLID CATALYSTS

Process for the preparation of polyisocyanates

MANUFACTURE OF 1-ALKENYLISOCYANATE

PRODUCTION OF POLYISOCYANATE

PURPOSE: To industrially advantageously obtain polymethylene polyphenyl polyisocyanate by thermally decomposing polymethylene polyphenyl polycarbamate in boiling organic solvent, forming thin film from reacted solution and further performing thermally decomposing reaction. CONSTITUTION: In production of polyisocyanate expressed by formula III by thermal decomposition in liquid phase of polycarbamate expressed by formula II (m is integer of 0-6; R is 1-6C alkyl), said raw material is thermally decomposed by two steps composed of first process in which said raw material is thermally decomposed in a boiling organic solvent with removing by-produced alcohol to out of the system and second process in which reaction product is formed to thin film at a point of time in decreasing of reaction speed with decreasing of amount of alcohol generation on the approach of finish of the reaction and further the thermal decomposition reaction is performed, then remained a small amount of alcohol is effectively ...

PROCESS FOR CONTINUOUS PREPARATION OF ISOCYANATE

PURPOSE: To obtain continuously the titled compound of high quality without forming polymeric by-products, by introducing a mixture of a carbamic acid ester with a thermal decomposition solvent from the top of a vertical tubular reactor, feeding the thermal decomposition solvent vapor from the bottom thereof, and thermally decomposing the mixture. CONSTITUTION: A mixture of a carbamic acid ester with a thermal decomposition solvent inert under reaction conditions (preferably in 5W30wt% concentration of the former) is continuously introduced from the top of a vertical tubular reactor packed with a solid packing material and/or solid catalyst, and a thermal decomposition solvent vapor is continuously introduced from the bottom of the reactor thereinto to carry out thermal decomposition at 140W380°C, preferably 180W330°C under a pressure to give the reaction temperature of the boiling point of the thremal decomposition solvent or below to take out a low-boiling product in the gaseous form ...

METHOD FOR TREATING CATALYST

PROBLEM TO BE SOLVED: To provide a method for treating a catalyst that reduces a production cost of an isocyanate while permitting industrially efficient production of the isocyanate. SOLUTION: A primary amine, urea and/or an N-unsubstituted carbamic acid ester and an alcohol are caused to react in the presence of a catalyst to give a carbamate followed by a thermal decomposition reaction of the carbamate to give an isocyanate and a residue, and subsequently the catalyst is recovered from the residue. The method for treating a catalyst permits the recovery of the catalyst used in the production process of the carbamate after the thermal decomposition process and therefore reduces a production cost of the isocyanate while permitting industrially efficient production of the isocyanate. COPYRIGHT: (C)2011,JPO&INPIT ...

СПОСОБ ПОЛУЧЕНИЯ ИЗОЦИАНАТОВ С ИСПОЛЬЗОВАНИЕМ ДИАРИЛКАРБОНАТА

FIELD: chemistry. SUBSTANCE: invention relates to a method of obtaining isocyanate. The method includes several stages. First, a reaction mixture, which contains arylcarbamate, containing an aryl group, formed from diarylcarbonate; an aromatic hydroxyl-compound, formed from diarylcarbonate, and diarylcarbonate, is obtained by realising interaction of diarylcarbonate and an amine compound in a reactor, in which a reaction between diarylcarbonate and the amine compound is carried out. After that, the reaction mixture is transferred into a reactor of thermal decomposition, connected by a line with the reactor, in which the reaction between diarylcarbonate and the amine compound is carried out. After that, isocyanate is obtained as a result of a reaction of thermal arylcarbamate decomposition. Diarylcarbonate includes a metal atom in a concentration from 0.001 ppm to 10%. Diarylcarbonate represents a compound of formula , where R 1 represents an aromatic group, containing from 6 to 12 carbon atoms. The amine compound represents a compound of formula , where R 2 represents a group, selected from an aliphatic group, containing from 1 to 20 carbon atoms, and an aromatic group, containing from 6 to 20 carbon atoms, and the said group contains an atom, selected from the carbon atom and oxygen atom, its valence equals to n and n represents an integer number from 2 to 10. EFFECT: method makes it possible to inhibit reactions of arylcarbamate denaturation, in this way providing the stable isocyanate obtaining with the high output for a long-term period. 30 cl, 16 dwg, 1 tbl, 27 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 523 201 C2 (51) МПК C07C 263/04 (2006.01) C07C 265/14 (2006.01) C07C 269/04 (2006.01) C07C 271/54 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ (21)(22) Заявка: ИЗОБРЕТЕНИЯ К ПАТЕНТУ 2010146077/04, 15.05.2008 (24) Дата начала отсчета срока действия патента: 15.05.2008 (72) Автор(ы): СИНОХАТА Масааки (JP), МИЯКЕ Нобухиса (JP) (43) ...

Способ получения дифенилметандиизоцианата

Использование: в производстве полиуретанов , лаков, клеев, пленок. Сущность изобретения: продукт - дифенилметандиизо- цианат. Реагент 1: метилендифенилуретан. Условия реакции: термическое разложение, серная кислота, бензолсульфокислота, п-толу олсулъфокислота в количестве 1-4 мас.% от мегилендифенилуретана, диметилфталат. СЛ d 00 tJ ЧО u Ы 00 ...

Verfahren zur Herstellung von organischen Polyisocyanaten

Die vorliegende Erfindung betrifft ein Verfahren zur Herstellung von organischen Polyisocyanaten, bei welchen in einem Spaltreaktor Polyurethane thermisch gespalten, anschließend eine Destillation durchgeführt wird und die hierbei anfallende Sumpffraktion rückgeführt wird, wobei die rückgeführte Sumpffraktion wenigstens teilweise zunächst in einen Reaktionsbereich und anschließend in den Spaltreaktor geleitet wird.

Mehrstufiges Verfahren zur kontinuierlichen Herstellung von cycloaliphatischen Diisocyanaten

Die Erfindung betrifft ein mehrstufiges Verfahren zur kontinuierlichen und phosgenfreien Herstellung von cycloaliphatischen Diisocyanaten.

VERFAHREN ZUR HERSTELLUNG VON ISOCYANATEN DURCH THERMISCHE SPALTUNG VON URETHANEN

Verfahren zur Herstellung von Isocyanaten

METHOD FOR PRODUCING CARBAMATE, METHOD FOR PRODUCING ISOCYANATE, CARBAMATE PRODUCTION SYSTEM, AND ISOCYANATE PRODUCTION SYSTEM

A method for producing carbamate including a urea production step; a carbamate-forming step: an ammonia separation step of absorbing the gas with water in the presence of carbonate to produce a gas absorption water, and separating ammonia; an aqueous alcohol solution separation step of separating an aqueous alcohol solution from the gas absorption water; an ammonia/carbon dioxide separation step of separating carbon dioxide gas from the aqueous ammonia solution in the gas absorption water from which the aqueous alcohol solution is separated; an aqueous ammonia solution reusing step of mixing the aqueous ammonia solution and carbonate with the water to be used for production of the gas absorption water. 1. A method for producing carbamate , the method comprising the steps of:a urea production step of producing urea by reaction between ammonia and carbon dioxide gas,a carbamate-forming step of producing carbamate by carbamate-forming reaction between amine, the urea, and alcohol, and by-producing a gas containing alcohol, ammonia, and carbon dioxide,an ammonia separation step of absorbing the gas with water to produce a gas absorption water, and separating ammonia,an aqueous alcohol solution separation step of separating an aqueous alcohol solution from the gas absorption water,an ammonia/carbon dioxide separation step of separating carbon dioxide gas from the aqueous ammonia solution in the gas absorption water from which the aqueous alcohol solution is separated, andan aqueous ammonia solution reusing step of using the aqueous ammonia solution along with the water for production of the gas absorption water.2. The method for producing carbamate according to claim 1 , whereinin the ammonia separation step, the gas is absorbed with the water in the presence of carbonate,in the ammonia/carbon dioxide separation step, carbon dioxide gas is separated from the aqueous ammonia solution in the presence of the carbonate, andin the aqueous ammonia solution reusing step, along ...

METHOD FOR PRODUCING TOLUENEDICARBAMATE, METHOD FOR PRODUCING TOLUENEDIISOCYANATE, AND TOLUENEDICARBAMATE

A method for producing toluenedicarbamate includes a carbamate production process of producing toluenedicarbamate by reaction between toluenediamine, urea, and/or N-unsubstituted carbamic acid ester, and alcohol; and a benzoyleneurea reduction process of reducing a disubstituted benzoyleneurea and a derivative thereof to 10 mol or less relative to 100 mol of toluenedicarbamate, wherein the disubstituted benzoyleneurea is represented by formula (1) below and has a methyl group and an amino group: 3. The method for producing toluenedicarbamate according to claim 2 , wherein the biuret compound reduction process comprises a first biuret compound reduction process of reducing a first biuret compound represented by formula (2) above where Xand Xare amino groups.4. The method for producing toluenedicarbamate according to claim 3 , further comprising a urea feeding process of feeding urea to the carbamate production process claim 3 ,wherein in the first biuret compound reduction process,when the urea feeding process includes a fluid feeding process, in which urea is melted by heating to be in a fluid state, and to be fed to the carbamate production process, the time after the melting of urea to the completion of its feeding is set to within 2 hours,in the urea feeding process, urea is fed as a slurry to the carbamate production process, orin the urea feeding process, urea is fed in a solid state to the carbamate production process.5. The method for producing toluenedicarbamate according to claim 2 , wherein the biuret compound reduction process comprises a second biuret compound reduction process of reducing a second biuret compound represented by formula (2) above where Xis an amino group or an alkoxy group and Xis an alkoxy group.6. The method for producing toluenedicarbamate according to claim 5 , further comprising an N-unsubstituted carbamic acid ester production process of producing N-unsubstituted carbamic acid ester by reaction between urea and alcohol claim 5 , ...

PROCESS FOR PREPARING POLYURETHANE PREPOLYMERS CONTAINING ISOCYANATE GROUPS

The present invention relates to the technical field of isocyanates. The present invention provides a method for preparing NCO prepolymers by reacting a stoichiometric excess of an organic isocyanate with an isocyanate-reactive component, the reaction components being mixed together and the mixture being introduced directly into a storage or transport vessel, where it reacts to completion. 111-. (canceled)12. A method for preparing an isocyanate group-containing prepolymer from an isocyanate group-containing component and an isocyanate group-reactive component , which comprisesmixing continuously the components in a mixing device and immediately after being mixedintroducing continuously the reaction mixture into a storage or transport vessel, where the reaction between the components is completed.13. The method according to claim 12 , wherein the storage or transport vessel has no means of mixing and/or cooling.14. The method according to claim 12 , wherein the transport vessel is the tank of a tanker vehicle.15. The method according to claim 12 , wherein the temperature in the vessel rises less than 60° C.16. The method according to claim 12 , wherein the proportion of isocyanate group-reactive component in the mixture is 0.1 to 10 weight %.17. The method according to claim 12 , wherein the mixing device comprises one or more static mixers.18. The method according to claim 12 , wherein in a first step of a batch production only a first reaction component is initially directed through the mixing device into the vessel claim 12 , before in a second step the second reaction component is directed into the mixing device in addition to the first reaction component claim 12 , where it is mixed with the first reaction component.19. The method according to claim 18 , wherein the reaction component directed through the mixing device in the first step of the batch production is the isocyanate group-containing component and the reaction component directed into the mixing ...

Method for Producing Carbonyl Compund

A method for producing a carbonyl compound of the present invention comprises a step (X) of reacting a specific compound having a urea bond with a carbonic acid derivative having a carbonyl group (—C(═O)—) under heating at a temperature equal to or higher than the thermal dissociation temperature of the urea bond to obtain the carbonyl compound. 2. The method for producing the carbonyl compound according to claim 1 , wherein the step (X) is carried out in the coexistence of a hydroxy compound.3. The method for producing the carbonyl compound according to claim 1 , wherein the carbonyl compound comprises an N-substituted carbamic acid ester.4. The method for producing the carbonyl compound according to claim 1 , wherein the carbonic acid derivative is urea or an N-unsubstituted carbamic acid ester.5. The method for producing the carbonyl compound according to claim 1 , wherein the carbonic acid derivative is a carbonic acid ester.7. The method for producing the carbonyl compound according to claim 1 , wherein the compound having the urea bond is a polyurethane-urea copolymer.9. The method for producing the carbonyl compound according to claim 8 , wherein the compound having the urea bond is a compound produced from an organic primary amine and a phosgene.10. The method for producing the carbonyl compound according to claim 1 , wherein the step (X) is carried out in a distillation column.11. A method for producing an isocyanate claim 1 , comprising a step of subjecting a carbonyl compound obtained by the production method according to claim 1 , to a pyrolytic reaction to produce the isocyanate.12. The method for producing the carbonyl compound according to claim 1 , whereinthe step (X) is carried out using a distillation column comprising a supply port A, a supply port B, and a discharge port C;the step (X) comprises steps of:supplying raw material ingredients containing the compound having the urea bond, or raw material ingredients containing a precursor of the ...

Method For Making Over-Indexed Thermoplastic Polyurethane Elastomer Precursor And Thermoplastic Polyurethane Elastomer Made From The Precursor

A method for making over-indexed thermoplastic polyurethane elastomer precursor. The precursor may be cross-linked. 1. A method for making a dried over-indexed thermoplastic polyurethane elastomer precursor having unreacted isocyanate moieties , the method comprising:combining reactants and reacting them to form an over-indexed thermoplastic polyurethane elastomer precursor,cooling the over-indexed thermoplastic polyurethane elastomer precursor in water to form cooled precursor,pelletizing the cooled precursor to form cooled precursor pellets,drying the cooled precursor pellets to a moisture concentration less than about 800 ppm to form dried over-indexed thermoplastic polyurethane elastomer precursor, andpackaging the dried over-indexed thermoplastic polyurethane elastomer precursor in moisture-resistant packaging under conditions that essentially maintain the moisture content of the dried over-indexed thermoplastic polyurethane elastomer precursor at or below about 800 ppm.2. The method of claim 1 , wherein the drying further comprises partially drying the cooled precursor pellets to a moisture concentration less than about 3 claim 1 ,000 ppm by heating to form partially dried precursor pellets and further drying the partially dried precursor pellets to a moisture concentration less than about 800 ppm in an inert gas flow to form dried over-indexed thermoplastic polyurethane elastomer precursor.3. The method of claim 1 , wherein the cooled precursor pellets are partially dried to a moisture concentration less than about 1 claim 1 ,000 ppm.4. The method of claim 2 , wherein the cooled precursor pellets are partially dried to a moisture concentration less than about 1 claim 2 ,000 ppm.5. The method of claim 1 , wherein the dried over-indexed thermoplastic polyurethane elastomer precursor has a moisture content of 500 ppm.6. The method of claim 5 , wherein the dried over-indexed thermoplastic polyurethane elastomer precursor has a moisture content of 300 ppm.7. The ...

METAL CARBAMATES FORMED FROM TOLYLENEDIAMINES

The invention provides metal carbamates of the general formula (I) 1. (canceled)3. The process according to claim 2 , wherein the alkyl groups R1 and R2 each comprise 2-18 carbon atoms in the chain.4. The process according to claim 2 , wherein the alkyl groups R1 and R2 each comprise 2-7 carbon atoms in the chain.5. The process according to claim 2 , wherein the alkyl groups R1 and R2 are selected from the group consisting of an ethyl claim 2 , propyl claim 2 , butyl claim 2 , 2-methylpropyl claim 2 , 3-methylbutyl claim 2 , n-pentyl claim 2 , 2-methoxyethyl claim 2 , 2-ethoxyethyl and a 2 claim 2 ,2 claim 2 ,2-trifluoroethyl group.6. The process according to claim 2 , wherein the alkyl groups comprise one or more heteroatoms.7. The process according to claim 2 , wherein the alkyl groups comprise one or more oxygen atoms.8. The process according to claim 2 , wherein no heteroatoms are present in R1 and R2.9. The process according to claim 2 , wherein R1 and R2 are identical.10. The process according to claim 2 , wherein R1 and R2 are branched or unbranched.11. The process according to claim 2 , wherein the metal carbamate is solid at room temperature. This application is a divisional of U.S. application Ser. No. 12/920,224 filed Aug. 30, 2010, which is a National Stage of PCT/EP2009/053170 filed Mar. 18, 2009, both of which are incorporated herein by reference. This application also claims the benefit of EP 08152943.0 filed Mar. 18, 2008.The invention provides metal carbamates formed from tolylenediamines and a process for preparing them.Carbamates have been known for a long time. They are prepared typically by reacting aromatic amines with stoichiometric amounts of a base and an organic carbonate.For the preparation of carbamates, a series of processes is known.In these processes, for example, Lewis acids, such as uranium salts (U.S. Pat. No. 3,763,217), aluminum turnings with iodine and Hg promoters (U.S. Pat. No. 4,550,188), zinc salts, iron salts, antimony salts ...

PREPARATION OF PET PRECURSOR

The invention relates to a process for preparation of radiopharmaceutical precursors, and in particular protected amino acid derivatives which are used as precursors for production of radiolabeled amino acids for use in in vivo imaging procedures such as positron emission tomography (PET). Particularly, the invention relates to a process for preparation of a precursor of the [F]-1-amino-3- fluorocyclobutanecarboxylic acid ([F] FACBC) PET agent and particularly to the work-up process of this precursor removing generated salts from the intermediate composition. 2. A process as claimed in wherein X is benzyl.3. A process as claimed in either or wherein R is ethyl.4. A process as claimed in any one of to wherein Y is tent-butyl carbamate (Boc).6. A process as claimed in any one of to wherein in step iii) the amount of water added is about half the amount of ethyl acetate added in step ii).7. A process as claimed in any one of to wherein in step iv) the acid added is HCl.8. A process as claimed in any one of to wherein in step iv) the washing includes washing with pure water claim 1 , with an aqueous solution of sodium hydrogen carbonate and with brine.9. A process as claimed in any one of to further including the steps of concentrating the composition from step iv) under reduced pressure claim 1 , drying and purifying.10. A process as claimed in any one of to wherein the crude reaction product includes a mixture of the syn- and anti-enantiomer of the compound of formula IIIa.12. A process as defined in wherein said leaving group is a halogen substituent or a group represented by —ORwherein Ris either a fluorosulfonic acid substituent or an aromatic sulfonic acid substituent.13. A process as defined in wherein said leaving group is selected from a toluenesulfonic acid substituent claim 12 , a nitrobenzenesulfonic acid substituent claim 12 , a benzenesulfonic acid substituent claim 12 , a trifluoromethanesulfonic acid substituent claim 12 , a fluorosulfonic acid ...

STABILIZED ISOCYANATE GROUP-CONTAINING ETHYLENICALLY UNSATURATED COMPOUND

An object of the present invention is to improve the stability of an ethylenically unsaturated compound having an isocyanate group in the molecule by preventing a polymerization of the ethylenically unsaturated compound. The present invention relates to a stabilizing composition for an isocyanate group-containing ethylenically unsaturated compound, comprising: an isocyanate group-containing ethylenically unsaturated compound (A) which comprises one or more isocyanate groups and one or more ethylenically unsaturated groups in the molecule; and a stabilizing agent (B) which is a compound in which at least one of the ethylenically unsaturated groups in the compound (A) is replaced with an alkyl group which may have a substituent. 1. A stabilizing composition for an isocyanate group-containing ethylenically unsaturated compound , comprising:an isocyanate group-containing ethylenically unsaturated compound (A) which comprises one or more isocyanate groups and one or more ethylenically unsaturated groups in the molecule; anda stabilizing agent (B) which is a compound in which at least one of the ethylenically unsaturated groups in the compound (A) is replaced with an alkyl group which may have a substituent.2. The stabilizing composition according to claim 1 , wherein the compound (A) is a compound comprising one or more ethylenically unsaturated groups represented by the following formula (1); and the stabilizing agent (B) is a compound in which at least one of the ethylenically unsaturated groups represented by the formula (1) in the compound (A) is replaced with a structure represented by the following formula (2) or (3):{'br': None, 'sup': 1', '2', '3, '—CR═CRR\u2003\u2003(1)'}{'sup': 1', '3, 'claim-text': {'br': None, 'sup': 4', '5', '6', '7', '8, '—CRR—CRRR\u2003\u2003(2)'}, '(wherein Rto Reach independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atoms or an aromatic group);'}{'sup': 4', '8, 'claim-text': {'br': None, 'sup': 9', '10', '11, '— ...

STABILIZED ISOCYANATE GROUP-CONTAINING ETHYLENICALLY UNSATURATED COMPOUND

An object of the present invention is to improve the stability of an ethylenically unsaturated compound having an isocyanate group in the molecule by preventing a polymerization, a multimerization reaction and a discoloration reaction of the ethylenically unsaturated compound. The present invention relates to a stabilizing composition for an isocyanate group-containing ethylenically unsaturated compound, comprising: an isocyanate group-containing ethylenically unsaturated compound (A) which comprises one or more isocyanate groups and one or more ethylenically unsaturated groups in the molecule; and a stabilizing agent (B) which is a compound in which at least one of the ethylenically unsaturated groups in the compound (A) is replaced with an alkyl halide group or an amino alkyl group which may have a substituent. 2. The stabilizing composition according to claim 1 , wherein the compound (A) is a compound comprising one or more ethylenically unsaturated groups represented by the following formula (1); and the stabilizing agent (B) is a compound in which at least one of the ethylenically unsaturated groups represented by the formula (1) in the compound (A) is replaced with a structure represented by the following formula (2) or (3):{'br': None, 'sup': 1', '2', '3, '—CR═CRR\u2003\u2003(1)'}{'sup': 1', '3, 'claim-text': {'br': None, 'sup': 4', '5', '6', '7', '8, '—CRR—CRRR\u2003\u2003(2)'}, '(wherein Rto Reach independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atoms or an aromatic group);'}{'sup': 4', '8', '4', '8, 'claim-text': {'br': None, 'sup': 9', '10', '11, '—CRRR\u2003\u2003(3)'}, '(wherein Rto Reach independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, an aromatic group, halogen, an alkylamino group or a dialkylamino group; and at least one of Rto Rrepresents halogen, an alkylamino group or a dialkylamino group);'}{'sup': 9', '11', '9', '11, '(wherein Rto Reach independently represent a hydrogen atom, an ...

PROCESS FOR THE PREPARATION OF RETIGABINE

This invention relates to a novel chemical process for the synthesis of 2-ethyoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene and its use in the preparation of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene (retigabine/ezogabine) and its polymorphic forms thereof. 2. A process as claimed in for the preparation of a compound of formula (I) or a salt thereof claim 1 , which further comprises reaction of 4-fluorobenzaldehyde and 4-amino-2-nitroaniline followed by reduction using standard procedures to produce a compound of formula (II).3. A process for the preparation of retigabine claim 1 , or a salt thereof claim 1 , which comprises the following steps:(i) reacting a compound of formula (II) with diethylcarbonate in the presence of a base to produce a compound of formula (I), or a salt thereof; and(ii) reduction of compound of formula (I) using standard procedures to produce retigabine;(iii) and optionally preparing a salt thereof.4. A process as claimed in for the preparation of retigabine claim 3 , or a salt thereof claim 3 , which further comprises reaction of 4-fluorobenzaldehyde and 4-amino-2-nitroaniline followed by reduction using standard procedures to produce a compound of formula (II).5. A process as claimed in wherein the base is selected from sodium ethoxide claim 1 , sodium hydride claim 1 , potassium tert-butoxide claim 1 , n-butyl lithium claim 1 , potassium hexamethyldisilylazide (KHMDS) claim 1 , cesium carbonate claim 1 , potassium hydroxide claim 1 , sodium pentoxide claim 1 , sodium tert-butoxide claim 1 , lithium ethoxide claim 1 , sodium hydroxide claim 1 , potassium ethoxide claim 1 , diisopropyl ethyl amine (DIPEA) claim 1 , 1 claim 1 ,8-diazabicylco[5.4.0]undec-7-ene (DBU) claim 1 , 1 claim 1 ,4-diazabicyclo[2.2.2]octane (DABCO) or lithium tert-butoxide.6. A process as claimed in wherein the base is sodium ethoxide.7. A process as claimed in wherein the base is present in range of 1.8 to 2.2 molar equivalents.8. A process ...

METHOD FOR PRODUCING TOLYLENE DIISOCYANATE

A method for producing tolylene diisocyanate includes: mixing a first diaminotoluene containing 2,4-diaminotoluene and 2,6-diaminotoluene at a first isomer ratio and a second diaminotoluene containing 2,4-diaminotoluene and/or 2,6-diaminotoluene at a second isomer ratio that is different from the first isomer ratio so as to prepare mixed diaminotoluene; producing tolylene dicarbamate by reaction of the mixed diaminotoluene, urea and/or N-unsubstituted carbamic acid ester and alcohol; and thermally decomposing the tolylene dicarbamate. 1. A method for producing tolylene diisocyanate containing 2 ,4-tolylene diisocyanate and 2 ,6-tolylene diisocyanate at a target isomer ratio , the method comprising:mixing a first diaminotoluene containing 2,4-diaminotoluene and 2,6-diaminotoluene at a first isomer ratio and a second diaminotoluene containing 2,4-diaminotoluene and/or 2,6-diaminotoluene at a second isomer ratio that is different from the first isomer ratio so as to prepare mixed diaminotoluene;producing tolylene dicarbamate by reaction of the mixed diaminotoluene, urea and/or N-unsubstituted carbamic acid ester and alcohol; andthermally decomposing the tolylene dicarbamate.2. The method for producing tolylene diisocyanate according to claim 1 ,wherein the first isomer ratio is 2,4-diaminotoluene/2,6-diaminotoluene (molar ratio)=79 to 81/21 to 19,the second isomer ratio is set such that a proportion of 2,4-diaminotoluene is higher than a proportion of 2,4-diaminotoluene in the first isomer ratio, andin the mixing step, the second diaminotoluene is mixed in an amount of 1 to 30 parts by mass per 100 parts by mass of the first diaminotoluene.3. The method for producing tolylene diisocyanate according to claim 1 ,wherein the second diaminotoluene is produced by decomposing isocyanate residues, which are obtained by separating tolylene diisocyanate and alcohol from a decomposition solution resulting from the thermal decomposition reaction of the tolylene dicarbamate in the ...

Two-step and one-pot processes for preparation of aliphatic diisocyanates

The present invention relates to using a two-step (thermolysis) or one-pot process to prepare aliphatic diisocyanates from aliphatic diamines and diaryl carbonates. Polyisocyanates can also be prepared from polyamines and diaryl carbonates. The present synthetic processes do not apply phosgene or highly toxic reagents and chloro-solvents during the entire procedure.

PROCESS FOR THE PREPARATION OF POLYISOCYANATES AND USE THEREOF

The invention relates to a process for isocyanate modification which includes reacting a) at least one organic isocyanate having an NCO functionality greater than or equal to 1, b) a catalyst comprising at least one phosphonium salt comprising at least one cycloalkyl substituent bonded directly to a P atom of a phosphonium cation, c) optionally a solvent, and d) optionally additives. The present invention also relates to a catalyst for isocyanate modification comprising at least one phosphonium salt comprising at least one cycloalkyl substituent bonded directly to a P atom of a phosphonium cation. 1. A process for isocyanate modification which comprises reactinga) at least one organic isocyanate having an NCO functionality greater than or equal to 1,b) a catalyst comprising at least one phosphonium salt comprising at least one cycloalkyl substituent bonded directly to a P atom of a phosphonium cation,c) optionally a solvent, andd) optionally additives.3. The process according to claim 2 , wherein Rto Rindependently of one another represent organic radicals selected from the group consisting of C- to C-alkyl which is optionally branched claim 2 , cyclopentyl claim 2 , and cyclohexyl which is optionally substituted claim 2 , and{'sub': 1', '4, 'wherein at least two of the radicals Rto Rrepresent an optionally substituted cyclopentyl, cyclohexyl radical, or combinations thereof which are each bonded directly to the P atom via a ring carbon atom.'}4. The process according to claim 2 , wherein the phosphonium cation of the formula (I) has a counter-ion X wherein X is selected from the group consisting of fluoride (F) and a di- or poly-(hydrogen) fluoride ([F×(HF)] claim 2 , wherein m represents whole or fractional numbers from 0.001 to 20.5. The process according to claim 1 , wherein the at least one organic isocyanate is selected from the group consisting of aliphatic di- or poly-isocyanates claim 1 , cycloaliphatic di- or poly-isocyanates claim 1 , araliphatic di- or ...

METHOD FOR PRODUCING TWO ISOCYANATES

The invention relates to a method for producing two isocyanates by reacting a first amine with phosgene in a stoichiometric excess in the gas phase to produce a first isocyanate, wherein the excess phosgene is subsequently recovered and recirculated back to react with a second amine to produce a second isocyanate. In another embodiment, both fresh and recycled phosgene may be used in reacting each respective amine to produce an isocyanate. The amine streams may be optimized to contain different concentrations of hydrogen chloride, as required for the production of two different isocyanates. 1. A continuous process for preparing a first isocyanate by gas phase phosgenation of a first amine , and a second isocyanate by gas phase phosgenation of a second amine , comprising:(i) reacting the first amine with freshly generated phosgene to obtain a first process product;(ii) treating the first process product with a first solvent at a temperature which is below the boiling point of the first isocyanate to give a gaseous stream (ii-1) containing hydrogen chloride and unreacted phosgene and a liquid stream (ii-2) containing the first solvent and the first isocyanate;(iii) feeding stream (ii-1) to a distillation column (iii) to give a liquid phosgene-containing stream (iii-1) and a gaseous stream (iii-2) containing hydrogen chloride;(iv) introducing stream (iii-1) to a distillation column (iv), from which a gaseous phosgene-containing stream (iv) is taken off at the top;(v) reacting the second amine with an excess of phosgene that comprises gaseous phosgene-containing stream (iv) to obtain a second process product;(vi) treating the second process product with a second solvent at a temperature which is below the boiling point of the second isocyanate to give a gaseous stream (vi-1) containing hydrogen chloride and unreacted phosgene and a liquid stream (vi-2) containing the second solvent and the second isocyanate;(vii) feeding stream (vi-1) to distillation column (iii);(viii) ...

METHOD FOR PRODUCING XYLYLENE DIISOCYANATE AND SYSTEM FOR PRODUCING XYLYLENE DIISOCYANATE

A method for producing xylylene diisocyanate includes a thermal decomposition step of thermally decomposing xylylene dicarbamate; a first separation step of separating, from the thermal decomposition product obtained in the thermal decomposition step, an isocyanate-containing component containing xylylene diisocyanate as a main component and an alcohol-containing component containing alcohol as a main component and containing xylylene diisocyanate as a subcomponent; a second separation step of separating xylylene dicarbamate and alcohol from the alcohol-containing component obtained in the first separation step; and a returning step of returning xylylene dicarbamate obtained in the second separation step to the thermal decomposition step. 1. A method for producing xylylene diisocyanate comprising:a thermal decomposition step of thermally decomposing xylylene dicarbamate, an isocyanate-containing component containing xylylene diisocyanate as a main component, and', 'an alcohol-containing component containing alcohol as a main component and containing xylylene diisocyanate as a subcomponent,, 'a first separation step of separating, from the thermal decomposition product obtained in the thermal decomposition step,'}a second separation step of separating xylylene dicarbamate and alcohol from the alcohol-containing component obtained in the first separation step, anda returning step of returning xylylene dicarbamate obtained in the second separation step to the thermal decomposition step.2. The method for producing xylylene diisocyanate according to claim 1 , wherein the alcohol-containing component has an alcohol content of 90 mass % or more relative to the total amount of the alcohol-containing component.3. A system of producing xylylene diisocyanate comprising:a thermal decomposition unit of thermally decomposing xylylene dicarbamate, an isocyanate-containing component containing xylylene diisocyanate as a main component, and', 'an alcohol-containing component ...

Separation Method and Method for Producing Isocyanate

Disclosed is a method for separating, with a multi-stage distillation column, a mixture containing an active hydrogen-containing compound (A) and a compound (B) that reversibly reacts with the active hydrogen containing compound (A), the method comprising distillation-separating the active hydrogen-containing compound (A) and the compound (B) with the multi-stage distillation column in the presence of an intermediate-boiling-point inactive compound (C) that has a normal boiling point between a normal boiling point of the active hydrogen-containing compound (A) and a normal boiling point of the compound (B) and is chemically inactive for both of the (A) and the compound (B). 1. A method for separating , with a multi-stage distillation column , a mixture containing an active hydrogen-containing compound (A) and 5 a compound (B) that reversibly reacts with the active hydrogen-containing compound (A) , the method comprising:distillation-separating the active hydrogen-containing compound (A) and the compound (B) with the multi-stage distillation column in the presence of an intermediate-boiling-point inactive compound (C) 10 that has a normal boiling point between a normal boiling point of the active hydrogen-containing compound (A) and a normal boiling point of the compound (B) and is chemically inactive for the active hydrogen-containing compound (A) and the compound (B),wherein the normal boiling point of the active hydrogen-containing compound (A) is lower than the normal boiling point of the compound (B).2. The method according to claim 1 , comprising supplying the mixture to an inactive layer comprising the intermediate-boiling-point inactive compound (C) claim 1 , formed within the multi-stage distillation column.3. The method according to claim 1 , comprising supplying the mixture in a gas state to the multi-stage distillation column.4. The method according to claim 1 , wherein the compound (B) is an isocyanate and/or an isothiocyanate.5. The method according to ...

N-Substituted Carbamic Acid Ester Production Method, Isocyanate Production Method Using Such N-Substituted Carbamic Acid Ester, and Composition for Transfer and Storage of N-Substituted Carbamic Acid Ester Comprising N-Substituted Carbamic Acid Ester and Aromatic Hydroxy Compound

The present invention is a method for producing an N-substituted carbamic acid ester derived from an organic amine from an organic amine, a carbonic acid derivative and a hydroxy composition containing one or more types of hydroxy compounds, wherein the organic amine, the carbonic acid derivative and the hydroxy composition are reacted using a urethane production reaction vessel provided with a condenser, a gas containing the hydroxy composition, the compound having the carbonyl group derived from the carbonic acid derivative, and an ammonia formed as a by-product in the reaction, is introduced into the condenser provided in the urethane production reaction vessel, and the hydroxy composition and the compound having the carbonyl group derived from the carbonic acid derivative are condensed, and wherein a stoichiometric ratio of a hydroxy compound contained in the condensed hydroxy composition to the condensed compound having the carbonyl group derived from the carbonic acid derivative is 1 or more, and a ratio of number of carbonyl groups (—C(═O)—) contained in the compound having the carbonyl group derived from the carbonic acid derivative and number of ammonia molecules contained in the ammonia recovered as a gas from the condenser is 1 or less. 141.-. (canceled)44. The method according to claim 42 , wherein the recovered aromatic hydroxy compound is reused.45. The production method according to claim 42 , wherein a residual liquid containing unreacted N-substituted carbamic acid-O-Ar ester recovered from a bottom of the thermal decomposition reaction vessel is again transferred to the thermal decomposition reaction vessel claim 42 , and the N-substituted carbamic acid-O-Ar ester is subjected to a thermal decomposition reaction.46. The production method according to claim 42 , wherein the isocyanate produced in the production method according to contains 1 to 1000 ppm of the aromatic hydroxy compound that composes the aromatic hydroxy composition based on the ...

ISOCYANATE PRODUCTION METHOD

An isocyanate production method according to the present invention is a method in which an isocyanate is produced by subjecting a carbamate to thermal decomposition, and includes: a step of preparing a mixture liquid containing the carbamate, an inactive solvent and a polyisocyanate compound; a step of conducting a thermal decomposition reaction of the carbamate by continuously introducing the mixture liquid into a thermal decomposition reactor; a step of collecting a low-boiling decomposition product by continuously extracting the low-boiling decomposition product in a gaseous state from the reactor, the low-boiling decomposition product having a boiling point lower than the polyisocyanate compound; and a step of collecting a high-boiling component by continuously extracting, from the reactor, a liquid phase component which is not collected in a gaseous state at the step of collecting the low-boiling decomposition product. 1. An isocyanate production method in which an isocyanate is produced by thermal decomposition of a carbamate , comprising:a step of preparing a mixture liquid comprising the carbamate and a polyisocyanate compound;a step of conducting a thermal decomposition reaction of the carbamate by continuously introducing the mixture liquid into a thermal decomposition reactor:a step of collecting a low-boiling decomposition product by continuously extracting the low-boiling decomposition product in a gaseous state from the thermal decomposition reactor, the low-boiling decomposition product having a standard boiling point lower than the polyisocyanate compound; anda step of collecting a high-boiling component by continuously extracting, from the thermal decomposition reactor, a liquid phase component which is not collected in a gaseous state at the step of collecting the low-boiling decomposition product, as the high-boiling component.2. The isocyanate production method according to claim 1 , wherein the mixture liquid comprises an inactive solvent claim ...

CONTINUOUS DILUTION OF POLYISOCYANATES

The invention relates to a process for producing a polyisocyanate composition comprising addition of at least one isocyanate-inert solvent to at least one polyisocyanate, characterized in that the addition of the solvent is carried out in one or more stages and at least one of these stages is performed as a continuous dilution. The invention further relates to the polyisocyanate compositions obtainable by the process, to the use of the polyisocyanate compositions, to a two-component system containing the polyisocyanate composition and to composite systems produced with the two-component system. 1. A process for producing a polyisocyanate composition comprising addition of at least one isocyanate-inert solvent to at least one polyisocyanate , wherein the addition of the solvent is carried out in one or more stages and at least one of these stages is performed as a continuous dilution.2. The process as claimed in claim 1 , wherein the polyisocyanate is based on at least one aliphatic claim 1 , cycloaliphatic claim 1 , araliphatic or aromatic diisocyanate.3. The process as claimed in claim 1 , wherein the polyisocyanate is based on tolylene diisocyanate.4. The process as claimed in claim 1 , wherein the addition of the solvent is carried out in at least two stages claim 1 , wherein the first stage is performed as a continuous dilution.5. The process as claimed in claim 1 , wherein a solids content of ≥30% to ≤90% by weight is established in the first stage.6. The process as claimed in claim 4 , wherein a solids content of ≥10% to ≤80% by weight is established in the second stage claim 4 , wherein the solids content established in the first stage is reduced by at least 15% by weight in the second stage.7. The process as claimed in claim 3 , wherein the polyisocyanate is produced from tolylene diisocyanate by(i) reaction of tolylene diisocyanate to form a polyisocyanate and(ii) removal of the unconverted tolylene diisocyanate down to a residual content of monomeric ...

GOLD-CATALYZED SYNTHESIS OF CARBONATES AND CARBAMATES FROM CARBON MONOXIDE

The invention provides a method for producing organic carbonates via the reaction of alcohols and carbon monoxide with oxygen adsorbed on a metallic gold or gold alloy catalyst. 2. The method of claim 1 , wherein X is O.3. The method of claim 1 , wherein X is NR.4. The method of claim 1 , wherein the source of the adsorbed oxygen is O.5. The method of claim 1 , wherein the source of the adsorbed oxygen is O.6. The method of claim 1 , wherein Ris C1-C8 straight chain alkyl.7. The method of claim 6 , wherein Ris methyl.8. The method of claim 1 , wherein Ris C1-C8 straight chain alkyl.9. The method of claim 8 , wherein Ris methyl.10. The method of claim 1 , wherein X is O claim 1 , and Rand Rare the same.11. The method of claim 1 , wherein X is O claim 1 , and Rand Rare different.12. The method of claim 1 , wherein Ris C1-C8 straight chain alkyl.13. The method of claim 1 , wherein ROH is supplied in the gas phase claim 1 , and the temperature is between 250 K and 300 K. This application claims benefit of U.S. provisional application No. 61/572,416, filed Jul.This invention was made with government support under DE-FG02-84-ER13289 awarded by the U.S. Department of Energy and under CHE-0952790 awarded by the National Science Foundation. The Government has certain rights in the invention.The invention is in the fields of synthetic organic chemistry and catalysis, and relates specifically to a process for preparing carbonates and carbamates. More particularly, the present invention relates to a process for preparing carbonates and carbamates via oxidative carbonylation in the presence of a metallic gold catalyst.Dialkyl carbonates are industrially useful as lubricants, fuel additives, and reactive reagents in a wide variety of processes. In particular, dimethyl carbonate (DMC) has found use as an environmentally-acceptable solvent, high-octane oxygenated fuel additive, and esterifying and methylating agent, and the future demand for DMC is projected to exceed current ...

PROCESS FOR THE PREPARATION OF URETHANES

Urethanes are prepared by oxidative carbonylation of at least one amino compound in the presence of carbon monoxide, oxygen and organic, at least one hydroxyl-group-carrying compound. The carbonylation is carried out in the absence of halogen-containing promoters. The carbonylation is also carried out in the presence of a metal complex catalyst which contains neutral bidentate N-chelate ligands of the (N˜N) type, two monoanionic N,O-chelate ligands of the general type (N˜O) or tetradentate dianionic chelate ligands (O˜N˜N˜O). 110-. (canceled)12. The process of claim 11 , wherein the metal complex catalyst is used in a concentration of from 0.1 to 10 mol % claim 11 , based on one mole of amino groups.13. The process of claim 11 , wherein the carbonylation is carried out in methanol claim 11 , ethanol claim 11 , n-butanol claim 11 , or 2 claim 11 ,2 claim 11 ,2-trifluoroethanol.14. The process of claim 11 , wherein ureas groups are formed during the carbonylation claim 11 , wherein these urea groups subsequently react further claim 11 , partially or completely claim 11 , with the organic hydroxyl-group-containing compound by alcoholysis to give the corresponding urethanes.15. The process of claim 11 , in which an aliphatic claim 11 , cycloaliphatic and/or aromatic mono- or di-amino compound is used.16. The process of claim 11 , in which the carbonylation is carried out in the absence of a halogenated solvent.17. A process for the preparation of isocyanates claim 11 , comprising:a) preparing a urethane by carbonylation by the process of 1, andb) thermally cleaving the urethane to obtain the isocyanate.18. The process of claim 17 , wherein the carbonylation and the thermal cleavage take place in one process step. The invention relates to a process for the preparation of urethanes and/or ureas by oxidative carbonylation of amino compounds in the presence of carbon monoxide and oxygen as oxidizing agents and, particularly in the case of the urethanes, in the presence of ...

SILICA-BASED ZINC CATALYSTS, THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES

The present invention relates to silica-based heterogeneous zinc compounds which are suitable as catalysts in the reaction of amines with dialkyl carbonates to produce carbamates. The catalysts have the formula [SiO]—CH—CHR—X—COOZn[Y], wherein [SiO] represents a silica carrier selected from the group consisting of ordered mesoporous silica and irregular amorphous narrow pore silica, R represents a moiety selected from the group consisting of hydrogen, —CH, and —CHCH, preferably hydrogen, X is an aliphatic chain of 2 to 11 carbon atoms that optionally comprises ether moieties and [Y] represents a mono anion. The invention is also directed towards a method for the preparation of the aforementioned compounds and towards method for the alkoxycarbonylation of amines. 1. A silica-based zinc compound of the formula{'br': None, 'sub': 2', '2, '[SiO]—CH—CHR—X—COOZn[Y]'}{'sub': 2', '2', '2, 'claim-text': [{'sub': 3', '2', '3, 'R represents a moiety selected from the group consisting of hydrogen, —CH, and —CHCH;'}, 'X is an aliphatic chain of 2 to 11 carbon atoms that optionally comprises ether moieties; and', '[Y] represents a mono anion., 'wherein [SiO] represents a silica carrier selected from the group consisting of ordered mesoporous silica and irregular amorphous narrow pore silica, said silica carrier [SiO2] being covalently bound to the terminal CHgroup of CH—CHR—X—COOZn[Y];'}2. The silica-based zinc compound according to claim 1 , wherein X is an aliphatic chain of 2 to 9 carbon atoms that optionally comprises ether moieties.3. The silica-based zinc compound according to claim 2 , wherein X is selected from the group consisting of —(CH)— claim 2 , —(CH)— and —CH—O—(CH)—.4. The silica-based zinc compound according to claim 1 , wherein said compound{'sub': 2', '2, '(a) has a structure A in which the mono anion [Y] comprises a carboxylate group, the carboxylate oxygen atoms coordinating to the zinc atom and the carboxylate carbon atom being covalently connected to the ...

METHODS OF SYNTHESIZING A LEVODOPA ESTER PRODRUG

Methods of synthesizing a levodopa ester prodrug, salts thereof, and synthetic intermediates thereof are disclosed.

A Process to Produce Polycarbamate, Polycarbamate Produced Thereby and a Coating Composition Comprising the Polycarbamate

A process to prepare polycarbamate comprising adding urea to a polyol in the presence of at least one catalyst selected from the group consisting of compounds having the following formula MZ; wherein M is a trivalent metal, and Z is an anionic functionality or a functionality capable of forming a covalent bond with M and wherein n times a valence number of Z equals X and m times three equals Y wherein the absolute value of X equals the absolute value of Y is provided. Also provided are a polycarbamate produced according to the process and a coating composition comprising the polycarbamate. 1. A process to prepare polycarbamate comprising:{'sub': m', 'n, 'adding urea to a polyol in the presence of at least one catalyst selected from the group consisting of compounds having the following formula MZ; wherein M is a trivalent metal selected from the group consisting of Bi(III), Al(III), Yb(III), Y(III), Fe(III), La(IIII), Sm(IIII), Ru(III), Ga(III), Sc(III) or Ce(III), and wherein Z is selected from the group consisting of 2-ethylhexanoate, benzoate, hexafluoroacetylacetonate, isopropoxide, acetyl acetonate, hydroxyl, phenoxide, stearate, tert-butoxide, neodecanoate, citrate, trifluoromethane sulfonate, n-butoxide, trifluoroacetate, 1,1,1-trifluoro-2,4-pentanedionate, 2,2,6,6,-tetramethyl-3,5-hexanedionate, cresylate, ethoxide, methoxide, triethanolaminato, 2-methyl-2-butoxide, oxo, fluoride, chloride, bromide, iodide, aryl or substituted aryl, mixtures thereof and chelates thereof, and wherein Z is an anionic functionality or a functionality capable of forming a covalent bond with M.'}2. The process according to claim 1 , wherein a second catalyst selected from the group consisting of carbamylation catalysts is present.3. The process according to claim 2 , wherein the second catalyst is dibutyltin oxide and/or dibutyltin acetate.4. (canceled)5. (canceled)4. The process according to claim 1 , wherein the catalyst is selected from the group consisting of: Bismuth(III) ...

ZINC CLUSTER COMPOUNDS AND THEIR USE AS CATALYSTS IN THE REACTION OF AMINES WITH DIALKYL CARBONATES

The present invention relates to metallic zinc cluster compounds which are suitable as catalysts in the reaction of amines with dialkyl carbonates to produce carbamates. The invention is also directed towards a method for the alkoxycarbonylation of amines. The cluster compound has a general formula which may be written as [M(OC—R)].[MO].[HO], wherein M is Zn, R is an unsubstituted or substituted aromatic, cycloaliphatic, linear aliphatic, or other organic rest, x is 1, y is ≧x is 1, y is ≧0.03 to ≦26.0 and z is >0.00 to ≦17.0. 1. A compound of the formula [Zn(OC—R)].[ZnO].[HO] 'x is 1, y is ≧0.03 to ≦26.0 and z is >0.00 to ≦17.0.', 'wherein R is an unsubstituted or substituted aromatic, cycloaliphatic, linear aliphatic, or other organic rest and'}2. The compound of claim 1 , wherein R is selected from the group of CH claim 1 , o- claim 1 , m- and p-CH—OMe claim 1 , o- claim 1 , m- and p-CH—OH claim 1 , p-CH—NFH claim 1 , p-CH—NO claim 1 , p-CH—Br claim 1 , o- and p-CH—CO claim 1 , 2-pyrrolidinyl claim 1 , heptadecanyl and/or CHCH(OH)CO.3. The compound of to claim 1 , wherein R is para-CH—OCHand wherein the zinc content as determined by thermogravimetric analysis is ≧20.0% to ≦45.0%.4. The compound of claim 1 , wherein R is para-CH—OCHand wherein the carbon content as determined by elemental analysis is ≧30.0% to ≦48.0% claim 1 , preferably ≧40.0 and ≦45.0.5. A method for producing the compound of claim 1 , comprising the steps of:{'sub': '2', 'A) providing an aqueous solution comprising a carboxylic acid HOC—R and a base, wherein R is an unsubstituted or substituted aromatic, cycloaliphatic, linear aliphatic, or other organic rest;'}B) providing an aqueous solution comprising a dissolved zinc salt; andC) combining the solutions of step A) and step B).6. The method of claim 5 , wherein R is selected from the group of CH claim 5 , o- claim 5 , m- and p-CH—OMe claim 5 , o- claim 5 , m- and p-CH—OH claim 5 , p-CH—NH claim 5 , p-CH—NO claim 5 , p-CH—Br claim 5 , o- and p ...

METHOD FOR PREPARING ALIPHATIC DIISOCYANATE

The present invention relates to a method for preparing an aliphatic diisocyanate by pyrolyzing an aliphatic dicarbamate in liquid phase, using a tin (II) or (IV) compound as a catalyst and a zwitterionic compound as a stabilizer, thereby remarkably inhibiting high-boiling by-products and providing the aliphatic diisocyanate with high yield. 2. The method according to claim 1 , wherein the aliphatic dicarbamate is 1 claim 1 ,2-bis(methoxycarbonylamino)ethane claim 1 , 1 claim 1 ,3-bis(methoxycarbonylamino)propane claim 1 , 1 claim 1 ,4-bis(methoxycarbonylamino)butane claim 1 , 1 claim 1 ,6-bis(methoxycarbonylamino)hexane claim 1 , 1 claim 1 ,6-bis(ethoxycarbonylamino)hexane claim 1 , 1 claim 1 ,6-bis(butoxycarbonylamino)hexane claim 1 , 1 claim 1 ,8-bis(methoxycarbonylamino)octane claim 1 , 1 claim 1 ,8-bis(butoxycarbonylamino)octane claim 1 , 1 claim 1 ,2-bis(methoxycarbonylamino)cyclohexane claim 1 , 1 claim 1 ,2-bis(butoxycarbonylamino)cyclohexane claim 1 , 1 claim 1 ,3-bis(methoxycarbonylamino)cyclohexane claim 1 , 1 claim 1 ,3-bis(butoxycarbonylamino)cyclohexane claim 1 , 1 claim 1 ,4-bis(methoxycarbonylamino)cyclohexane claim 1 , 1 claim 1 ,4-bis(butoxycarbonylamino)cyclohexane claim 1 , 1 claim 1 ,2-bis(methoxycarbonylaminomethyl)cyclohexane claim 1 , 1 claim 1 ,2-bis(butoxycarbonylaminomethyl)cyclohexane claim 1 , 1 claim 1 ,3-bis(methoxycarbonylaminomethyl)cyclohexane claim 1 , 1 claim 1 ,3-bis(butoxycarbonylaminomethyl)cyclohexane claim 1 , 1 claim 1 ,4-bis(methoxycarbonylaminomethyl)cyclohexane claim 1 , 1 claim 1 ,4-bis(butoxycarbonylaminomethyl)cyclohexane claim 1 , 4.4-methylenedi(methoxycarbonylaminocyclohexane) claim 1 , 4.4-methylenedi(butoxycarbonylaminocyclohexane) claim 1 , bis(methoxycarbonyl)isophorone claim 1 , or bis(butoxycarbonyl) isophorone.3. The method according to claim 1 , wherein the tin (II) or (IV) compound is bis(tri-n-butyltin)oxide claim 1 , bis(tri-n-butyltin) sulfate claim 1 , di-n-butyldiphenyltin claim 1 , di-n-butyltin bis( ...

ISOCYANATE PRODUCTION METHOD

An isocyanate production method is characterized by having: a carbamation step in which a carbonic acid ester, an inorganic acid salt of an amino acid derivative, and a basic compound are reacted to obtain a reaction mixture containing a carbamic acid ester derived from the carbonic acid ester, a hydroxy compound derived from the carbonic acid ester, and the carbonic acid ester; and a thermal decomposition step in which the carbamic acid ester is subjected to a thermal decomposition reaction to obtain an isocyanate. 1. A production method of a carbamic acid ester derived from a carbonic acid ester , comprising supplying the carbonic acid ester , an inorganic acid salt of an amino acid derivative , and a basic compound to a carbamation reactor to allow reaction to proceed.3. The production method of a carbamic acid ester according to claim 2 , wherein the amino acid derivative is an amino acid ester claim 2 , the production method further comprising a production step of the inorganic acid salt of the amino acid ester by reacting an amino acid and a compound having an alcoholic hydroxy group in a presence of an inorganic acid.4. The production method of a carbamic acid ester according to claim 3 , wherein the basic compound is an organic amine.5. The production method of a carbamic acid ester according to claim 4 , wherein the carbonic acid ester comprises 0.001 ppm by mass to 10% by mass of a metallic atom claim 4 , relative to a total mass of the carbonic acid ester.6. The production method of a carbamic acid ester according to claim 5 , wherein the inorganic acid salt of the amino acid derivative is supplied to the carbamation reactor in a liquid state.7. An isocyanate production method comprising: a thermal decomposition step in which a carbamic acid ester prepared by a production method of a carbamic acid ester of is subjected to a thermal decomposition reaction to obtain an isocyanate.8. The isocyanate production method according to claim 7 , wherein the thermal ...

FLEXIBLE TO RIGID NANOPOROUS POLYURETHANE-ACRYLATE (PUAC) TYPE MATERIALS FOR STRUCTURAL AND THERMAL INSULATION APPLICATIONS

Novel urethane-acrylate (UAC) Star monomers and polyurethane-acrylate (PUAC) aerogel polymers derived therefrom are described herein, along with other novel, related monomers and polymers. Also described herein are processes for preparing the UAC Star monomers, the PUAC aerogel polymers, and the other related monomers and polymers. The PUAC and related polymers herein are useful in various applications including in structural and thermal insulation. 2. The urethane-acrylate star monomer of wherein the nitrogen atoms of the urethane moieties are attached to their respective aryl rings at the 4-positions of the aryl rings.3. The urethane-acrylate star monomer of wherein W═X═Y═CHCH.4. The urethane-acrylate star monomer of wherein each of R1-R9 is a hydrogen.5. The urethane-acrylate star monomer of wherein the nitrogen atoms of the urethane moieties are attached to their respective aryl rings at the 4-positions of the aryl rings; wherein W═X═Y═CHCH; and wherein each of R1-R9 is a hydrogen.6. A polyurethane-acrylate polymer formed by the polymerization of the urethane-acrylate star monomer of in the presence of a polymerization catalyst.7. The polyurethane-acrylate polymer of claim 6 , wherein the polymerization catalyst is a free radical initiator.8. The polyurethane-acrylate polymer of claim 7 , wherein the free radical initiator is 2 claim 7 ,2′-azobisisobutyronitrile.9. A polyurethane-acrylate polymer formed by the copolymerization of the urethane-acrylate star monomer of with a polymerization chain extender claim 1 , in the presence of a polymerization catalyst.10. The polyurethane-acrylate polymer of claim 9 , wherein the polymerization chain extender is a compound comprising from 2 to 4 acrylate groups or from 2 to 4 methacrylate groups claim 9 , or a combination thereof.11. The polyurethane-acrylate polymer of claim 10 , wherein the chain extender is a compound comprising 2 acrylate groups.15. The polyurethane-acrylate polymer of wherein the nitrogen atoms of the ...

MULTISTEP PROCESS FOR THE PREPARATION OF DIISOCYANATES

The present invention relates to a process for the preparation of organic diisocyanates by cleaving the corresponding diurethanes into the diisocyanate and a hydroxy compound and separating the diisocyanate from the hydroxy compound by distillation wherein the diisocyanate is obtained as the distillate. 2. The process according to claim 1 , wherein the diarylurethanes of the formula (3) is prepared from organic diamines claim 1 , carbonic acid derivatives and aromatic hydroxy compounds.3. The process according to claim 2 , wherein the organic diamine is selected from the group consisting of 2 claim 2 ,4-toluylendiamine claim 2 , 2 claim 2 ,6-toluylendiamine claim 2 , 2 claim 2 ,2′-diaminodiphenylmethane claim 2 , 2 claim 2 ,4′-diaminodiphenylmethane claim 2 , 4 claim 2 ,4′-diaminodiphenylmethane claim 2 , 1 claim 2 ,5-naphthalenediamine claim 2 , 1 claim 2 ,3-diaminobenzene claim 2 , 1 claim 2 ,4-diaminobenzene claim 2 , m-xylylenediamine claim 2 , p-xylylendiamine claim 2 , 1 claim 2 ,4-butanediamine claim 2 , neopentanediamine claim 2 , 1 claim 2 ,5-pentanediamine claim 2 , 1 claim 2 ,5-diamino-2-methylpentane claim 2 , 2-butyl-2-ethyl-1 claim 2 ,5-pentanediamine claim 2 , 1 claim 2 ,6-hexanediamine claim 2 , 2 claim 2 ,5-diamino-2 claim 2 ,5-dimethylhexane claim 2 , 1-amino-3 claim 2 ,3 claim 2 ,5-trimethyl-5-aminomethyl-cyclohexane claim 2 , 1 claim 2 ,4-cyclohexanediamine claim 2 , 2 claim 2 ,4-hexahydrotoluenediamine claim 2 , 2 claim 2 ,6-hexahydrotoluenediamine claim 2 , isomers of hexahydroxylylendiamine claim 2 , isomers of bis-(aminomethyl)norbornane claim 2 , and mixtures of the aforementioned.4. The process according to claim 2 , wherein the carbonic acid derivative is urea claim 2 , diarylcarbamate or dialkylcarbonate.5. The process according to claim 2 , wherein the aromatic hydroxy compound is selected from the group consisting of phenol claim 2 , o-cresol claim 2 , m-cresol claim 2 , p-cresol claim 2 , 2 claim 2 ,6-xylenol claim 2 , 2 claim 2 ,5- ...

MULTISTEP PROCESS FOR THE PREPARATION OF HEXAMETHYLENE DIISOCYANATE, PENTAMETHYLENE DIISOCYANATE OR TOLUENE DIISOCYANATE

The present invention relates to a multistep process for the preparation of organic diisocyanates by converting the corresponding diamine precursors, urea and hydroxy compounds into monomeric diurethanes, converting these diurethanes into diurethanes of high boiling hydroxy compounds, and finally cleavage of the latter diurethanes to form the diisocyanates and recover the high boiling hydroxy compounds. 2. The process according to claim 1 , wherein the molecular mass of R′—OH is at least 40 g/mol lower than the molecular mass of R″—OH.3. The process according to claim 1 , wherein the primary diamine (1) for formation of the diurethanes of the general formula (3) is 1 claim 1 ,5-pentanediamine (PDA) or 1 claim 1 ,6-hexanediamine (HDA).4. The process according to claim 1 , wherein the hydroxy compound R′—OH used for the formation of the diurethanes of the general formula (3) that has a standard boiling point between ≥80° C. and ≤210° C.5. The process according to claim 1 , wherein the hydroxy compound R″—OH has a standard boiling point between ≥280° C. and ≤370° C.6. The process according to claim 1 , wherein a catalyst is present during the transesterification step.7. The process according to claim 1 , wherein the cleavage reaction is a thermolytic cleavage carried out in a thin film evaporator.8. The process according to claim 1 , wherein a catalyst is used in the cleavage reaction.9. The process according to claim 1 , wherein the molecular mass of R′—OH is at least 100 g/mol lower than the molecular mass of R″—OH.10. The process according to claim 1 , wherein the molecular mass of R′—OH is between ≥110 g/mol and <160 g/mol lower than the molecular mass of R″—OH The present invention relates to a multistep process for the preparation of organic diisocyanates by converting the corresponding diamine precursors, urea and hydroxy compounds into monomeric diurethanes, converting these diurethanes into diurethanes of high boiling hydroxy compounds, and finally cleavage of ...

WATER FEED METHODS TO CONTROL MW DISTRIBUTION AND BYPRODUCTS OF THE CARBAMYLATION OF UREA

The present invention provides methods for making a polycarbamate by feeding a) a urea in fluid form into a reaction medium containing b) an alkyd polyol, such as a short or med oil alkyd polyol to form a reaction mixture and then carbamylating the alkyd polyol by heating the reaction mixture while feeding water in to the reaction mixture, preferably, in the presence of one or more c) carbamylation catalysts. The polycarbamate of the present invention when combined with a polyaldehyde or an acetal or hemiacetal thereof as a second component makes a multicomponent composition that is substantially isocyanate-free, and cures at a temperature of from 0° C. to less than 80° C. to form a crosslinked polyurethane. 1. A method of making a polycarbamate for use in making polyurethanes feeding one or more a) ureas or alkyl carbamates in fluid form into a reaction medium containing one or more b) alkyd polyols to form a reaction mixture and then carbamylating the alkyd polyol by heating the reaction mixture while feeding water into the reaction mixture.2. The method as claimed in claim 1 , wherein at least one of the b) alkyd polyols has a hydroxyl number of from 50 to 250.3. The method as claimed in claim 1 , wherein at least one of the b) alkyd polyols is a short or med oil alkyd polyol.4. The method as claimed in claim 1 , wherein at least one of the b) one or more alkyd polyols is the reaction product of one or more monocarboxylic acid oils claim 1 , one or more polycarboxylic acids having two or more carboxylic acid claim 1 , salt or acyl halide groups or the anhydride thereof claim 1 , and one or more polyalcohols having three or more hydroxyl groups.5. The method as claimed in claim 4 , wherein the one or more monocarboxylic acid oil used to make the at least one of the b) alkyd polyols is chosen from oleic acid claim 4 , lauric acid claim 4 , coconut oil claim 4 , sunflower oil claim 4 , and mixtures thereof.6. The method as claimed in claim 1 , wherein the one or ...

Process for preparing isocyanate compound

A process for preparing an isocyanate compound is provided. The process includes a step of reacting an amine compound A having at least one primary amino group with CO2 and an organotin compound S having at least one radical OR3 attached to the tin atom of the organotin compound to convert at least one of the primary amino groups in the amine compound A into a carbamate group to obtain a carbamate compound C; a step of cleaving the carbamate groups in the obtained carbamate compound C to form the isocyanate compound and an alcohol R3OH, without separation of the tin compounds; and a step of obtaining the isocyanate compound. The radical R3 is a C-bound organic radical of 1-30 carbon atoms with 1, 2, or 3 carbon atoms optionally replaced by oxygen or nitrogen.

ELECTROCHEMICAL SYNTHESIS OF DICARBAMATES

The invention relates to an electrochemical process for preparing bis-O-alkyl-carbamates from primary amines with COas carbonyl source and at least one alkyl halide with at least three carbon atoms in the alkyl group as alkylating agent. 1. An electrochemical process for preparing bis-O-alkyl-carbamates comprising alkylating a primary diamines with COas carbonyl source and with an alkylating agent containing at least one alkyl halide having at least three carbon atoms in the alkyl group in the presence of at least one iodide source , wherein the process is carried out at 10° C. to 215° C.2. The electrochemical process according to claim 1 , wherein the process is carried out at 20° C. to 215° C.3. The electrochemical process according to claim 1 , wherein the iodide source is used in an amount of at least 0.5 mol-% claim 1 , relative to the alkyl halide/the sum of the alkyl halides.4. The electrochemical process according to claim 1 , wherein the iodide source is selected from the group consisting of symmetrically-substituted tetralkyl ammonium iodides claim 1 , asymmetrically-substituted tetralkyl ammonium iodides and sodium iodide.5. The electrochemical process according to claim 1 , wherein the iodide source is selected from the group consisting of tetrabutyl ammonium iodide (TBAI) and tetraethyl ammonium iodide (TEAI).6. The electrochemical process according to claim 1 , wherein the alkyl halide is activated by heat treatment at 60° C. to 215° C.7. The electrochemical process according to claim 1 , wherein the primary diamine is selected from aliphatic primary diamines and aromatic primary diamines.8. The electrochemical process according to claim 1 , wherein the primary diamine is selected from the group consisting of 1 claim 1 ,6-diaminohexane claim 1 , 4 claim 1 ,4′-methylenebis(cyclohexylamine) claim 1 , 5-Amino-1 claim 1 ,3 claim 1 ,3-trimethylcyclo-hexanemethyl-amine claim 1 , 1 claim 1 ,4-diaminobenzene and 2 claim 1 ,4-diaminotoluene.9. The process ...

METHOD FOR PRODUCING ISOCYANATES

The invention relates to a method for producing an isocyanate, wherein a carbamate or thiolcarbomate is converted, in the presence of a catalyst, with separation of an alcohol or thioalcohol, at a temperature of at least 150° C., to the corresponding isocyanate, wherein a compound of the general formula (X)(Y)(Z—H) is used as a catalyst, in particular characterized in that the compound has both a proton donor function and a proton acceptor function. In the catalysts according to the invention, a separable proton is bound to a heteroatom, which is more electronegative than carbon. Said heteroatom is either identical to Z or a component thereof. In the catalysts according to the invention, there is additionally a proton acceptor function which is either identical to X or a component thereof. According to the invention, the proton donator and proton acceptor function are connected to each other by the bridge Y. 1. A process for producing an isocyanate in which a carbamate or thiolcarbamate is converted into the corresponding isocyanate in the presence of a catalyst with elimination of an alcohol or thioalcohol at a temperature of at least 150° C. ,wherein the catalyst used comprises a compound of the general formula (X)(Y)(Z—H), where: [{'sup': '1', 'X is N(R),'}, {'sup': '2', 'Y is C(R) or is a bridge formed of 2 carbon atoms which are part of a ring system comprising 5 or 7 carbon atoms with alternating double and single bonds, or is a bridge formed of 3, 5 or 7 carbon atoms with alternating single and double bonds, and'}, {'sup': 6', '(+)', '7', '8, 'Z is O, S, N(R) or N(R)(R), and'}, {'sub': 'B', 'wherein the catalyst has a pKat 25° C. of ≥3.00; or'}], '(A)'} X is O,', {'sup': '2', '—Y is C(R) or is a bridge formed of 2 carbon atoms which are part of a ring system comprising 5 or 7 carbon atoms with alternating double and single bonds, or is a bridge formed of 3, 5 or 7 carbon atoms with alternating single and double bonds, and'}, 'Z is O; or, '(B)'} X is O,', {' ...

Preparation of isocyanates from carbodiimides

ORGANIC CARBODIIMIDES ARE REACTED WITH CARBON MONOXIDE AND/OR CARBON DIOXIDE IN THE PRESENCE OF A CATALYST AT AN ELEVATED PRESSURE AND ELEVATED TEMPERATURE TO PRODUCE ORGANIC ISOCYANATES. THE CATALYST IS PREFERABLY AT LEAST ONE METAL OR COMPOUND OF A METAL FOUND IN GROUPS IB, IIB, IIIB, IVA, IVB, VIA,VIB,IIIA,VIIA,VIII, AND IN THE LANTHANIDE SERIES OF THE PERIODIC TABLE.

一种具有高反应活性的固体酸催化剂及其制备方法和应用

本发明公开了一种具有高反应活性的固体酸催化剂及其制备方法和应用，所述催化剂以重量份数计，包括100份载体，18‑36份磺酸基，活性锌含量为8‑16份的锌基团，活性锆含量为10‑20份的锆基团，活性铝含量为7‑14份的铝基团，所述磺酸基通过化学连接在载体上，所述锌基团、锆基团、铝基团通过化学连接和/或物理附着在载体上；所述载体1有机碳骨架的多孔结构，其单元结构的化学式为：1,4‑二[二(3‑咔唑基)‑甲基)]苯，通过碳基骨架负载酸和活性位点进行催化反应，在HDI合成过程中具有高催化活性，同时具有容易回收、低成本、不会腐蚀化工设备的优点。

Formation of carbamates in the process of cu(i) complexes

Cu[NCMe 4 ]X, K[CuX 2 ], [(CuX)(S)] n (X=Cl, Br, I ; S =용매)의 구조식 (X=Cl, Br, I)을 갖는 1가의 할로겐화 구리화합물, 또는 구조식[Cu(CO)X a L b ] m Y n (X=CF 3 CO 2 , Cl, HB(pz) 3 (pz = pyrazoyl, C 3 H 3 N 2 ), LBF 2 {LBF 2 = difluoro-3,3'-(trimethylenedinitrilo)bis(2-butanone oximato)borate}; L = en, diene; Y=BPh 4 , AsF 6 ; a,b =0, 1 ; m =1-4; n=0,1)의 카르보닐기 (Cu-CO)를 갖는 1가의 구리 화합물 중에서 선택된 1종 이상의 촉매 존재 하에서 아민을 알코올 및 CO/O 2 혼합가스와 반응시키는 것으로 되는 카바메이트류의 제조방법이 제공된다. Monovalent having the structural formula (X = Cl, Br, I) of Cu [NCMe 4 ] X, K [CuX 2 ], [(CuX) (S)] n (X = Cl, Br, I; S = solvent) Copper halide, or structural formula [Cu (CO) X a L b ] m Y n (X = CF 3 CO 2 , Cl, HB (pz) 3 (pz = pyrazoyl, C 3 H 3 N 2 ), LBF 2 { LBF 2 = difluoro-3,3 '-(trimethylenedinitrilo) bis (2-butanone oximato) borate}; L = en, diene; Y = BPh 4 , AsF 6 ; a, b = 0, 1; m = 1-4 a process for producing carbamate wherein the amine is reacted with an alcohol and a CO / O 2 mixed gas in the presence of at least one catalyst selected from a monovalent copper compound having a carbonyl group (Cu-CO) of n = 0,1); Is provided.

Blocked polyisocyanates obtained from 2,2,4-trimethylhexamethylene-diisocyanate and acetoacetic acid alkyl esters

The subject of the invention are completely or partially blocked diisocyanates of the following formula (III) <IMAGE> (III) wherein R1 denotes the radical <IMAGE> or NCO and R denotes the methyl, ethyl, propyl, iso-propyl, n-butyl, tert.-butyl, iso-butyl, sec.-butyl, pentyl, hexyl, heptyl, octyl, nonyl, decyl and dodecyl radical.

Method of producing isocyanate

FIELD: chemistry. SUBSTANCE: invention relates to a method of producing isocyanate via thermal decomposition of an ester of carbamic acid. The method involves the following steps: extracting a low-boiling point component in form of a gas-phase component from a chemical reactor for conducting thermal decomposition, wherein a thermal decomposition reaction is carried out; extracting a liquid-phase component containing an ester of carbamic acid from the bottom part of the chemical reactor for conducting thermal decomposition; and feeding all or a portion of the liquid-phase component into the top part of the chemical reactor for conducting thermal decomposition. The ester of carbamic acid is obtained by reacting an ester of carboni acid of formula (where R 1 denotes an aliphatic group containing 1-12 carbon atoms, or an aromatic group containing 6-12 carbon atoms) with an amino compound of formula (where R 2 is a group selected from a group consisting of an aliphatic group containing 1-20 carbon atoms, and an aromatic group containing 6-20 carbon atoms, wherein said group contains an atom selected from carbon and oxygen atoms and has valence equal to n, and n is an integer from 2 to 10). EFFECT: method enables to obtain isocyanates over a long period of time, thus avoiding clogging of the chemical reactor caused by by-products sticking to reactor walls. 28 cl, 11 dwg, 1 tbl, 27 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2 483 058 (13) C2 (51) МПК C07C 263/04 C07C 263/18 C07C 265/14 (2006.01) (2006.01) (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (72) Автор(ы): СИНОХАТА Масааки (JP), МИЯКЕ Нобухиса (JP) (21)(22) Заявка: 2010146085/04, 15.05.2008 (24) Дата начала отсчета срока действия патента: 15.05.2008 (43) Дата публикации заявки: 20.05.2012 Бюл. № 14 R U (73) Патентообладатель(и): АСАХИ КАСЕИ КЕМИКАЛЗ КОРПОРЕЙШН (JP) Приоритет(ы): (22) Дата подачи заявки: 15.05.2008 (45) Опубликовано: 27.05.2013 Бюл. № 15 2 4 8 3 0 5 8 ...

Method for preparing isocyanate by pipeline phosgene method

本申请涉及一种制备异氰酸酯的方法。具体地，本申请提供了一种通过管道光气化法制备异氰酸酯的方法。

Process for producing isocyanate using diaryl carbonate

본 발명의 목적은, 포스겐을 사용하지 않고 이소시아네이트를 제조함에 있어서, 선행기술에서 볼 수 있는 여러가지 문제점이 없고, 고수율로 이소시아네이트를 장기간 안정적으로 제조할 수 있는 방법을 제공하는 것에 있다. 본 발명은, 탄산디아릴과 아민 화합물을, 반응 용매로서 방향족 히드록시 화합물의 존재하에 반응시켜, 탄산디아릴에서 유래하는 아릴기를 갖는 카르바민산아릴과, 탄산디아릴에서 유래하는 방향족 히드록시 화합물과, 탄산디아릴을 함유하는 반응 혼합물을 얻는 공정과, 상기 반응 혼합물을 열분해 반응기로 이송하는 공정과, 상기 카르바민산아릴을 열분해 반응시킴으로써 이소시아네이트를 얻는 공정을 포함하는 이소시아네이트의 제조 방법으로서, 탄산디아릴과 아민 화합물의 반응이 이루어지는 반응기와, 카르바민산아릴의 열분해 반응기가 상이한 이소시아네이트의 제조 방법을 개시한다.

Process for the preparation of polyisocyanates of the diphenylmethane series

본 발명은 디페닐메탄디아민과 폴리페닐폴리메틸렌폴리아민과의 상응하는 혼합물을 1종 이상의 용매의 존재 하에 포스겐과 단계적 반응시키고, 이때, 제 1 단계에서, 상응하는 카바모일 클로라이드 및 아민 히드로클로라이드가 형성되고, 후속 단계에서, 잔류 카바모일 클로라이드는 상응하는 폴리이소시아네이트 및 염화수소로 해리되며 아민 히드로클로라이드는 포스겐화되어 궁극적으로 상응하는 폴리이소시아네이트가 형성되며, 과잉의 잔류 포스겐이 반응 혼합물로부터 제거되는 시점에 일부 아민 히드로클로라이드가 미반응된 채 남아 있는, 훈터랩(HunterLab) 색(L)수가 높은 디페닐메탄 디이소시아네이트 및 폴리페닐폴리메틸렌 폴리이소시아네이트를 포함하는 혼합물의 제조 방법에 관한 것이다. 포스겐화, 훈터랩(HunterLab) 색(L)수, 디페닐메탄 디이소시아네이트, 폴리페닐폴리메틸렌 폴리이소시아네이트 The present invention stepwise reacts a corresponding mixture of diphenylmethanediamine with polyphenylpolymethylenepolyamine with phosgene in the presence of at least one solvent, wherein in the first step, the corresponding carbamoyl chloride and amine hydrochloride are formed In a subsequent step, residual carbamoyl chloride is dissociated into the corresponding polyisocyanate and hydrogen chloride and the amine hydrochloride is phosgenated to ultimately form the corresponding polyisocyanate, some at the time when excess residual phosgene is removed from the reaction mixture. A method for preparing a mixture comprising HunterLab high color (L) number diphenylmethane diisocyanate and polyphenylpolymethylene polyisocyanate in which amine hydrochloride remains unreacted. Phosgenation, HunterLab Color (L) Water, Diphenylmethane Diisocyanate, Polyphenylpolymethylene Polyisocyanate

Method of producing n-methylcarbamates

Process for the production of N-methylcarbamates: (wherein RO- is the radical of a substituted phenol or of a naphthol), wherein: - in a first reaction step methylamine and diphenyl carbonate are reacted with each other, operating in the liquid phase and as a continuous process, in order to form phenol and phenyl-N-methylurethane; - in a second reaction step phenyl-N-methylurethane, within the related reaction mixture outcoming from the first step, is thermally continuously decomposed, to yield a gaseous stream containing methyl isocyanate, from which the components different to methyl isocyanate are condensed off; - in a third step the methyl isocyanate stream, outcoming from the second step. after a possible preliminary condensation, is continuously fed and contacted with a solution of a substituted phenol or of a naphthol in an inert organic solvent, containing a basic catalyst, to form N-methylcarbamate (I); N-methylcarbamate (I) is finally recovered from the reaction mixture outcoming from the third step.

Method for producing isocyanate

本发明提供可抑制副反应且连续地制造异氰酸酯的异氰酸酯的制造方法，其是通过氨基甲酸酯的热分解来制造异氰酸酯的方法，其包括下述工序：热分解工序，将包含氨基甲酸酯和具有特定结构的化合物(A)的混合液连续地导入到热分解反应器中，进行氨基甲酸酯的热分解反应；低沸点分解产物回收工序，将标准沸点低于上述化合物(A)的低沸点分解产物从上述热分解反应器中以气态连续地排出；以及高沸点成分回收工序，将在上述低沸点分解产物回收工序中未以气态回收的液相成分作为高沸点成分从上述热分解反应器中连续地排出。

Method of manufacturing aromatic urethane

내용 없음. No content.

Method for Preparing Aliphatic Diisocyanates

본 발명은 지방족 디이소시아네이트(aliphatic diisocyanates)의 제조방법에 관한 것으로서 보다 상세하게는 지방족 디카바메이트(aliphatic dicarbamate)를 바나디아계 촉매 존재하에서 열분해시켜 촉매 없이 지방족 디카바메이트를 열분해시켜 지방족 디이소시아네이트를 제조하는 방법에 비해 고분자 부산물의 생성을 억제하면서 고수율의 지방족 디이소시아네이트를 제조할 수 있는 방법에 관한 것이다. More particularly, the present invention relates to a process for producing aliphatic diisocyanates by pyrolyzing an aliphatic dicarbamate in the presence of a vanadia catalyst to pyrolyze an aliphatic di-carbamate without a catalyst to obtain an aliphatic diisocyanate The present invention relates to a method for producing an aliphatic diisocyanate having a high yield while suppressing the production of a polymeric by-product.

Method for producing carbamate

Cu[NCMe 4 ]X, K[CuX 2 ], [(CuX)S)] n (X=Cl, Br, I; S=용매)의 구조식 (X=Cl, BR, I)을 갖는 1가의 할로겐화 구리화합물, 또는 구조식 [Cu(CO)X a L b ] m Y n (X=CF 3 CO 2 , Cl, HB(PZ) 2 (PZ=pyrazoyl, C 3 H 3 N 2 ), LBF 2 {LBF 2 =difluoro-3,3'-(trimethylenedinitrilo)bis(2-butanone oximato)borate}; L=en, diene; Y=BPh 4 , AsF 6 ; a, b=0, 1; m=1 -4; n=0, 1)의 카르보닐기(Cu-CO)를 갖는 1가의 구리 화합물 중에서 선택된 1종 이상의 촉매 존재 하에서 아민을 알코올 및 CO/O 2 혼합가스와 반응시키는 것으로 되는 카바메이트류의 제조방법이 제공된다.

Process for converting urethanes to isocyanates

A PROCESS FOR PRODUCING ISOCYANATES FROM URETHANES WHICH COMPRISES HEATING A URETHANE OF THE FORMULA: R(NHCOOR'')X WHEREIN R IS ALKYL OF FROM 1 TO 18 CARBON ATOMS, ARYL OR ALKARYL CONTAINING LESS THAN 3 RINGS, R'' IS ALKYL OF 1 TO 6 CARBON ATOMS, ARYL OR ALKARYL OF LESS THAN THREE RINGS, AND X IS 1, 2 OR 3, AT A TEMPERATURE BETWEEN 400*C. AND 600*C. IN THE PRESENCE OF A LEWIS ACID TO FORM VAPORS AND CONDENSING THE VAPORS TO RECOVER AN ORGANIC ISOCYANATE.

Process for preparing isocyanate compounds

A process for preparing diisocyanate compounds by the following two-step reaction without using phosgene. In the first step, a diamine and dimethyl carbonate are reacted with each other in the presence of an alkali catalyst to synthesize a corresponding urethane compound and, in the second step, the urethane compound is thermally decomposed in a high-boiling solvent under a reduced pressure of 1 to 700 Torr in the presence of a catalyst composed of a simple substance of metal selected from among manganese, molybdenum, tungsten, zinc, and beryllium or a compound thereof to obtain a corresponding diisocyanate compound.

CIRCUIT PROCESS FOR PRODUCING (CYCLO) ALIPHATIC DIISOCYANATES

.alpha.,.beta.-DIHALOALKYL ISOCYANATES AND A PROCESS FOR THE PREPARATION OF SUCH COMPOUNDS

O.Z. 0050/033479 Abstract of the Disclosure: .alpha.,.beta.-Dihaloalkyl isocyanates and a process for the preparation of such compounds by reacting .alpha.,.beta.-unsaturated alkyl isocynates with halogen in the presence of an organic solvent which is inert under the reaction conditions, at from -35 to +90°C. The .alpha.,.beta.-dihaloalkyl isocyanates thus obtainable corres-pond to the formula I where Rl, R2 and R3 are identical or different and each is hydrogen, a saturated aliphatic radical of 1 to 10 carbon atoms, a cycloaliphatic radical of 3 to 12 carbon atoms, an araliphatic radical of 7 to 11 carbon atoms or an aromatic radical of 6 to 10 carbon atoms, or Rl and R2 together with the carbon atom on which they are present as substituents are cycloalkyl of 3 to 7 ring members, and X is halogen. The compounds are valu-able intermediates for the preparation of dyes, surface-coating intermediates, crop protectlon agents and drugs.

Device and method for producing hexamethylene-1, 6-dicarbamate

本发明提供一种六亚甲基‑1,6‑二氨基甲酸甲酯的制造装置及制造方法，其中所述制造装置包括反应器、1,6‑己二胺供应装置、碳酸二甲酯供应装置与第一蒸馏塔。1,6‑己二胺供应装置连接至反应器。碳酸二甲酯供应装置连接至反应器。第一蒸馏塔连接至反应器的出料口。第一蒸馏塔包括上段塔、下段塔与压缩机。压缩机连接在下段塔的气体出口与上段塔的气体入口之间。所述六亚甲基‑1,6‑二氨基甲酸甲酯的制造装置与制造方法可有效地降低在生产六亚甲基‑1,6‑二氨基甲酸甲酯时的能耗与生产成本。

Method of preparing alpha,beta-dihalogenalkylisocyanates

Synthesis of polyisocyanates of diphenylmethane family

FIELD: chemistry. ^ SUBSTANCE: present invention relates to a method of preparing mixtures which contain diphenylmethane diisocyanates and polyphenyl polymethylene polyisocyanates, used in preparing polyurethane compositions for producing plastics, insulation materials, adhesives, coatings etc. The method involves a step for reacting corresponding mixtures of diphenylmethane diamines and polyphenyl polymethylene polyamines with phosgene in the presence of at least one solvent in several steps. At the first step, corresponding carbomoyl chlorides and amine hydrochlorides are formed, and at the next step residual carbamoyl chlorides are dissociated to corresponding polyisocyanates and hydrogen chloride, and the amine hydrochlorides undergo phosgenation to form corresponding polyisocyanates in the end. At the step for removing excess phosgene, the remaining unreacted amount of solid amine hydrochlorides, which lies between 10 and 5000 parts per million, is monitored. ^ EFFECT: cheap method of producing polyisocyanate mixtures, having a brighter colour, usually having colour index L in HunterLab coordinates higher than 10, without addition of extra reagents which reduce brightening and/or use of additional equipment. ^ 9 cl, 1 ex, 1 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2 415 129 (13) C2 (51) МПК C07C C07C C07C C08G 263/10 (2006.01) 263/20 (2006.01) 265/14 (2006.01) 18/76 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ, ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21)(22) Заявка: 2007144511/04, 23.05.2006 (24) Дата начала отсчета срока действия патента: 23.05.2006 (72) Автор(ы): СМИТ Ричард К. (GB), КАРР Роберт Г. (BE) R U (73) Патентообладатель(и): ХАНТСМЭН ИНТЕРНЭШНЛ ЛЛС (US) Приоритет(ы): (30) Конвенционный приоритет: 30.05.2005 EP 05104608.4 (43) Дата публикации заявки: 10.06.2009 Бюл. № 16 2 4 1 5 1 2 9 (45) Опубликовано: 27.03.2011 Бюл. № 9 (56) Список документов, цитированных в отчете о поиске: US 6576788 B1, 10.01.2003. DE ...

Method for producing carbamate and method for producing isocyanate

本发明提供一种包括下述工序(1)和工序(2)的氨基甲酸酯的制造方法等。(1)使用一分子中具有至少1个伯氨基的有机伯胺与二氧化碳和碳酸衍生物中的至少任一种，在低于脲键的热解离温度的温度下，制造具有脲键的化合物(A)的工序；(2)使上述化合物(A)与碳酸酯反应来制造氨基甲酸酯的工序。

PROCESS FOR THE PREPARATION OF N, O-DISSUBSTITUED URETANAS AND ITS APPLICATION AS STARTING MATERIAL FOR THE PREPARATION OF ORGANIC ISOCIANATES

Multistep process for the preparation of diisocyanates

The present invention relates to a process for the preparation of organic diisocyanates by cleaving the corresponding diurethanes into the diisocyanate and a hydroxy compound and separating the diisocyanate from the hydroxy compound by distillation wherein the diisocyanate is obtained as the distillate.

Process for preparing urethanes

1. Process for the preparation of urethanes by reacting a) unsubstituted or substituted ureas which do however still contain at least one hydrogen atom attached to a urea nitrogen atom, with b) organic compounds containing at least one hydroxyl group and c) carbon monoxide in the presence of d) molecular oxygen and e) a catalyst system containing at least one noble metal and/or noble metal compound of the eighth sub-group of the periodic system of elements, characterised in that the reaction is carried out in the presence of catalyst systems e) which contain as a further component at least one quinoid compound having oxidizing action and/or at least one compound which can be converted, under the reaction conditions, into a quinoid compound having oxidizing action.

New isocyanic ester manufacturing processes

Manufacture of mixture of diphenylmethanee diisocyanate and polyphenyllpolymethylenee polyisocyanate

Multistage continuous preparation of (cyclo) aliphatic diisocyanates

Disclosed is a multistage process for a continuous and phosgene-free preparation of a (cyclo)aliphatic diisocyanate. The process comprises (A) reacting a (cyclo)aliphatic diamine of the formula: H2N-R-NH2 (in which R is a bivalent (cyclo)aliphatic hydrocarbon radical) with urea and an alcohol of the formula: R1-OH (in which R1 is an aliphatic or cycloaliphatic radical) to form a (cyclo)alkylenebisurea of the formula: H2N-OC-HN-R-NH-CO-NH2; (B) converting the (cyclo)alkylenebisurea with the alcohol to a (cyclo)alkylenediurethane of the formula: R1O-OC-HN-R-NH-CO-OR1 in a reaction mixture which also contains low, medium and high boiler by-products; (C) removing the low, medium and high boiler impurities from the (cyclo)alkylenediurethane; (D) thermally cleaving the (cyclo)alkylenediurethane to form the (cyclo)aliphatic diisocyanate of the formula: OCN-R-NCO; (E) discharging a portion of a cleavage residue from a cleavage apparatus and reurethanizing it with the alcohol to obtain a reurethanization product; and (F) recycling the reurethanization product directly into the low-boiler impurity removed.

The synthetic method of N- chloroformyls-N [(4- trifluoromethoxies) phenyl] methyl carbamate

本申请提供一种N‑氯甲酰基‑N[(4‑三氟甲氧基)苯基]氨基甲酸甲酯的合成方法，该方法将溶于甲苯的4‑三氟甲氧基苯胺与氯甲酸甲酯在50~110℃反应即可生成N‑[(4‑三氟甲氧基)苯基]氨基甲酸甲酯，无需加入缚酸剂，能有效减少副反应的发生，后续产品质量较好。此外，上述合成方法中采用叔丁醇钠或叔丁醇钾作为活化碱试剂，避免使用反应活性很高的钠氢做活化碱试剂，使生产过程更加安全，极大地降低了事故发生率。

Process for the preparation of urethanes

PROCESS FOR THE PREPARATION OF URETHANES ABSTRACT OF THE DISCLOSURE The instant invention relates to an improved pro-cess for the preparation of urethanes by the reaction of aromatic nitro compounds with alcohols and carbon monoxide in the presence of catalyst systems which contain selenium.

Multistage continuous preparation of cycloaliphatic diisocyanates

Disclosed is a multistage process for continuous and phosgene-free preparation of a (cyclo)aliphatic diisocyanate, which comprises (1) reacting a (cyclo)aliphatic diamine with (i) urea or a urea derivative and (ii) an alcohol, while simultaneously removing formed ammonia, to form a (cyclo)aliphatic diurethane in a reaction mixture which also contains low, medium and high boiler by-product components: (2) removing the alcohol and the low and medium boiler components from the reaction mixture to obtain the (cyclo)aliphatic diurethane also containing the high boiler component; (3) thermally cleaving the (cyclo)aliphatic diurethane without a solvent in the presence of a catalyst in an apparatus, to release the desired (cyclo)aliphatic diisocyanate while leaving a cleavage residue containing the uncleaved (cyclo)aliphatic diurethane and the high boiler component; (4) discharging a portion of the cleavage residue from the apparatus, re-urethanizing it with the alcohol and then removing the high boiler component; and (5) recycling the (cyclo)aliphatic diurethane formed in step (4) to the step (1), (2) or (3). The process ensures good plant availability and good process yield, by avoiding viscous deposits promoted by the high boiler components.

Patent FR2479209B1

PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES

PROCESS FOR THE DEHYDROGENOFLUORATION OF AN AROMATIC CARBAMOYL FLUORIDE

PROCESS FOR THE MANUFACTURE OF AROMATIC ISOCYANATES BY CARBONYLATION OF NITER DERIVATIVES IN THE PRESENCE OF SUPPORTED CATALYSTS PREPARED FROM HETEROPOLYMETALLIC COMPLEXES

PROCEDE DE FABRICATION D'ISOCYANATES AROMATIQUES PAR CARBONYLATION DE DERIVES NITRES EN PRESENCE DE CATALYSEURS CONTENANT COMME PHASE ACTIVE, DEPOSES SUR UN SUPPORT, DES PARTICULES OU UN OXYDE D'UN METAL NOBLE DU GROUPE VIII ET D'UN METAL CHOISI DANS LES FAMILLES V, VI, ET VIII DE LA CLASSIFICATION PERIODIQUE, CARACTERISE EN CE QUE LE PRECURSEUR DE LA PHASE ACTIVE EST UN COMPLEXE HETEROPOLYMETALLIQUE, ET PLUS PARTICULIEREMENT UN CLUSTER MIXTE BIMETALLIQUE. PROCESS FOR THE MANUFACTURE OF AROMATIC ISOCYANATES BY CARBONYLATION OF NITER DERIVATIVES IN THE PRESENCE OF CATALYSTS CONTAINING AS ACTIVE PHASE, DEPOSITED ON A SUPPORT, PARTICLES OR AN OXIDE OF A NOBLE METAL OF GROUP VIII AND OF A CHOOSED METAL IN THE V FAMILIES, VI, AND VIII OF THE PERIODIC CLASSIFICATION, CHARACTERIZED IN THAT THE PRECURSOR OF THE ACTIVE PHASE IS A HETEROPOLYMETALLIC COMPLEX, AND MORE PARTICULARLY A MIXED BIMETALLIC CLUSTER.

Patent FR2228056A1

Process for preparing (-)-(1s,4r) n-protected 4-amino-2-cyclopentene-1-carboxylate esters

The invention relates to a process for preparing (-)-(1S,4R) N protected 4-amino-2-cylcopentene-1-carboxylate esters represented by formula (I) wherein R1 and R2 are as described within the specification.

PROCESS FOR THE PREPARATION OF N-MONOSUBSTITUTED CARBAMIC ACID ESTERS

LA PRESENTE INVENTION CONCERNE UN PROCEDE DE PREPARATION D'ESTERS D'ACIDE CARBAMIQUE N-MONOSUBSTITUES. SELON CE PROCEDE, ON FAIT REAGIR UN ESTER D'ACIDE CARBAMIQUE NON SUBSTITUE DE FORMULE NHCOR OU R EST UN GROUPE ALCOYLE A CHAINE DROITE OU RAMIFIEE CONTENANT DE 1 A 10 ATOMES DE CARBONE, AVEC UNE AMINE PRIMAIRE AROMATIQUE AYANT LA FORMULE R(NH)N OU R EST UN GROUPE ARYLE OU ARALCOYLE SUBSTITUE OU NON SUBSTITUE CONTENANT UN OU PLUSIEURS NOYAUX BENZENOIDES QUI PEUVENT ETRE CONDENSES OU REUNIS PAR DES LIAISONS DE COVALENCE SIMPLES ET OU N EST UN NOMBRE ENTIER VARIANT DE 1 A 6, A UNE TEMPERATURE COMPRISE DANS UN INTERVALLE D'ENVIRON 125C A 250C EN PRESENCE D'UN ALCOOL ALIPHATIQUE MONOHYDRIQUE AYANT DE 1 A 10 ATOMES DE CARBONE. LES PRODUITS OBTENUS SONT UTILES NOTAMMENT COMME PRODUITS CHIMIQUES POUR L'AGRICULTURE OU COMME INTERMEDIAIRES CHIMIQUES. THE PRESENT INVENTION RELATES TO A PROCESS FOR THE PREPARATION OF N-MONOSUBSTITUTE CARBAMIC ACID ESTERS. ACCORDING TO THIS PROCESS, AN NON-SUBSTITUTED CARBAMIC ACID ESTER OF NHCOR FORMULA OR R IS A STRAIGHT OR BRANCHED ALCOHYL GROUP CONTAINING 1 TO 10 CARBON ATOMS, WITH AN AROMATIC PRIMARY AMINE OF THE FORMULA R (NH) N OR R IS AN ARYL OR ARALCOYL SUBSTITUTED OR NOT SUBSTITUTES CONTAINING ONE OR MORE BENZENOID CORES WHICH CAN BE CONDENSED OR JOINED BY SINGLE COVALENCE BONDS AND OR N IS AN ENTIRE NUMBER VARIING FROM 1 TO 6, AT A TEMPERATURE INTERVAL OF APPROXIMATELY 125C TO 250C IN THE PRESENCE OF AN ALIPHATIC MONOHYDRIC ALCOHOL WITH 1 TO 10 CARBON ATOMS. THE PRODUCTS OBTAINED ARE USEFUL IN PARTICULAR AS CHEMICALS FOR AGRICULTURE OR AS CHEMICAL INTERMEDIARIES.

PROCESS FOR THE PRODUCTION OF ALIPHATIC ISOCYANATES

Treating compound having halophore carbon atom with carbamoyl fluoride comprises heating compound and carbamoyl fluoride

Treating a compound having a halophore carbon atom with a carbamoyl fluoride comprises heating the compound and the carbamoyl fluoride to at least 70 deg C and maintaining the ratio (Q) of hydrogen fluoride + carbamoyl fluoride to exchangeable halogen + isocyanate functions + carbamoyl fluoride at 2 or less.

Aromatic isocyanates prepn - from nitro, nitroso, azo or azoxy cpds with carbon monoxide, using cobalt carbonyl catalysts

Aromatic isocyanates are prepd. by reacting aromatic nitro, nitroso, azo or azoxy cpds. with CO at increased temp. and press, in presence of a Co carbonyl catalyst. The process can be used on an industrial scale. The isocyanate are used in prodn. of polyurethane foams and as inters in prepn. of coatings, foamed and cast synthetics, drying oils and resins.

Process for preparing alkyl isocyanates

IMPROVED PROCESS FOR PREPARING ALKYL ISOCYANATES Abstract Process for the production of alkyl isocyanates which can be defined by the general formula: R-N=C=O wherein R is an alkyl radical having from 1 to 4 carbon atoms by thermal decomposition of phenyl-N-alkyl urethans which can be defined by the general formula: wherein R has the above defined meaning. Said thermal decomposition is carried out without any substance having a catalytic activity being present in the decomposition reaction, by heating to a temperature of from 180°C to 210°C under the atmospherical pressure or a slighly reduced pressure, a mixture of phenol and phenyl-N-alkyl urethan, in a molar ratio of the former to the latter equal to or nearly equal to 1:1, removing by vaporization the phenol and the alkyl isocyanate from said vaporized products and maintaining in the reaction mixture, substantially throughout the thermal decomposition a molar ratio of phenol to phenyl-N-alkyl urethan not lower than about 1:1.

PROCEDURE FOR THE PREPARATION OF AROMATIC ORGANIC ISOCYANATES

Process for the preparation of carbamates

1. A process for the preparation of a carbamate of the formula see diagramm : EP0083764,P5,F1 where R**1 is an aliphatic, cycloaliphatic or araliphatic radical or R**3-(OR**2)n -, R**2 is an aliphatic radical of not less than 2 carbon atoms, R**3 is an aliphatic, cycloaliphatic or araliphatic radical, and n is an integer, by reacting urea with an alcohol, wherein urea is reacted with an alcohol of the formula R**1-OH where R**1 has the above meaning, at not less than 140 degrees C and under not less than 2 bar, an inert gas being passed through the reaction mixture and the pressure during the reaction being so set that the reaction mixture boils.

Process for preparing isocyanates

一种制备异氰酸酯的方法，它包括在有一种有机非质子传递溶剂和一种选自一种膦嗪化合物，一种有机含氮碱和它们的混合物的碱存在的情况下，使二氧化碳与一种伯胺接触，以产生相应的氨基甲酸铵盐，其中有机含氮碱选自胍类化合物、脒类化合物、叔胺类和它们的混合物；使氨基甲酸铵盐和一种酐脱水剂反应，产生一个包含相应的异氰酸酯，有机非质子传递溶剂和从酐衍生出的碱盐的产品物流；从产品物流中分离出碱盐；回收和循环碱；以及再生和循环酐脱水剂。

Process for the continuous production of isocyanates

Process for the preparation of alkyl isocyanates

Multistep process for the preparation of alkyl mono and diisocyanates consisting in reacting the corresponding aliphatic amine or diamine with dimethylcarbonate and, substantially, in partially vaporizing and converting the urethane thus formed in an evaporator to subsequently terminate the cracking in a II° reactor, and finally subjecting the cracking product to fractional distillation at reduced pressure, recycling the unconverted part to the partial vaporization step.

Patent FR2139577A5

An organic isocyanate is prepared by reacting a trisubstituted urea with hydrogen chloride in a solvent for the urea at a temperature below the boiling point of the solvent.

Reactor for thermally cracking monofunctional and polyfunctional carbamates

Process for the preparation of polyisocyanates

ABSTRACT OF THE DISCLOSURE Polyisocyanates are prepared by thermally splitting a carbamate corresponding to the formula: R1(NH-CO-O-R2)n in which R1, R2 and n are as defined herein into the corresponding isocyanate and alcohol. The split-ting reaction is carried out at a temperature of from 150 to 350°C, at a pressure of from 0.0001 to 20 bar and in the presence of an auxiliary agent. Suitable auxil-iary agents are hydrogen chloride, organic acid chlor-ides, compounds having an alkylating effect and organotin (IV) chlorides. Inert solvents and catalysts may also be employed in the splitting products. The thus-produced isocyanate and alcohol are then separated, if necessary.

Reaction and purification system and process for aliphatic or alicyclic dicarbamate

本发明公开了一种脂肪族或环族二氨基甲酸酯的反应及提纯系统及工艺，其包含：气液混合反应釜，其包含釜体，具有废气排出口、进气口及反应产物出口；与反应产物出口连通的刮膜蒸发器；与废气排出口连通的尾气吸收塔；该气液混合反应釜还包含：搅拌器，该搅拌器包含若干搅拌桨及一搅拌轴；及，设置在搅拌桨之下的若干第一气体分布器；该搅拌轴的下端为空心部，该空心部的第一端通过釜体的进气口与进气管道连通，该空心部的第二端位于所述搅拌桨及第一气体分布器之间。本发明提供的反应及提纯系统反应转化率高、能耗小、提纯后的产物纯度高，副产物气体回收处理方便、成本较低、操作简便，适用于氨基甲酸酯类化合物的工业化大生产。

Continuous process for the synthesis of aromatic urethanes

Process for the preparation of aromatic urethanes consisting in reacting organic carbonates with aromatic amines in reactors operating in continuous, feeding a total quantity of aromatic amines in a percentage, with respect to the weight of the total mixture, ranging from 4 to 30, and maintening a low concentration of amine in the reactor.

Process for the preparation of alkyl isocyanates

Process for the preparation of hexamethylene diisocyanate-1,6 and/or of the isomeric diisocyanates with 6 carbon atoms in the alkyl group

Method for the preparation of 1-alkenylisocyanates

Process for the preparation of organic isocyanates

A B S T R A C T PROCESS FOR THE PREPARATION OF ORGANIC ISOCYANATES Process for the preparation of organic isocyanates by reacting an aromatic nitro compound with carbon monoxide in the presence of (a) Pd or a Pd compound, (b) a ligand of formula

Process for producing isocyanates

An object of the present invention is to provide a process allowing long-term, stable production of isocyanates at a high yield without the various problems found in the prior art during production of isocyanates without using phosgene. The present invention discloses a process for producing an isocyanate by subjecting a carbamic acid ester to a decomposition reaction in the presence of a compound having an active proton and a carbonic acid derivative.

Isocyanate production method

The isocyanates are obtained by thermal decomposition of methyl carbamatesin a method wherein, to a liquid reaction medium composed of an inertorganic solvent with a high boiling point, a methyl carbamate stream and,simultaneously, an inert organic solvent stream with a low boiling point areadded, wherein the boiling point is intermediate between that of isocyanateand that of methanol and which is capable of forming an azeotropic mixturewith methanol itself. The method makes it possible to obtain isocyanateswith a high yield and selectivity.

Catalytic process for the direct carbonylation of organic nitro compounds

Isocyanates, or derivatives thereof, are produced from nitrobenzene or 2,4-dinitrotoluene by reaction with carbon monoxide in the presence of an iron, ruthenium, rhodium, or platinum carbonyl as catalyst.

Multi-stage process for the continuous preparation of cycloaliphatic diisocyanates

Die Erfindung betrifft ein mehrstufiges Verfahren zur kontinuierlichen und phosgenfreien Herstellung von cycloaliphatischen Diisocyanaten. The invention relates to a multi-stage process for the continuous and phosgene-free preparation of cycloaliphatic diisocyanates.

Process for producing isocyanate

본 발명의 목적은, 포스겐을 사용하지 않고 이소시아네이트를 제조할 때에, 선행 기술에서 볼 수 있는 여러 가지 문제점이 없고, 고수율로 이소시아네이트를 장기간 안정되게 제조할 수 있는 방법을 제공하는 것에 있다. 본 발명은 활성 프로톤을 갖는 화합물 및 탄산 유도체 존재 하에서, 카르밤산에스테르를 분해 반응시키는 것을 특징으로 하는 이소시아네이트를 제조하는 방법을 개시한다. An object of the present invention is to provide a method for producing isocyanate stably for a long time with high yield, without various problems seen in the prior art when producing isocyanate without using phosgene. The present invention discloses a process for producing an isocyanate characterized by decomposing a carbamic acid ester in the presence of a compound having an active proton and a carbonic acid derivative.

Process for producing isocyanates

Provided is a process for producing isocyanates from carbamic acid esters which comprises thermally decomposing carbamic acid esters in the presence of a catalyst containing at least one compound selected from the group consisting of organic sulfonic acids and alkaline metal salts of organic sulfonic acids. Thereby, a high thermal decomposition rate can be provided and isocyanate can be obtained in a high yield.

Isocyanate production process

An object of the present invention is to provide a process that enables isocyanate to be produced stably over a long period of time and at high yield without encountering problems of the prior art during production of isocyanate without using phosgene. The present invention discloses a process for producing an isocyanate by subjecting a carbamic acid ester to a thermal decomposition reaction, including the steps of: recovering a low boiling point component in a form of a gaseous phase component from a thermal decomposition reaction vessel in which the thermal decomposition reaction is carried out; recovering a liquid phase component containing a carbamic acid ester from a bottom of the thermal decomposition reaction vessel, and supplying all or a portion of the liquid phase component to an upper portion of the thermal decomposition reaction vessel.

Process for the manufacture of amine hydrochlorides containing an aliphatic acyl radical and new compounds resulting therefrom

Method for producing carbamate and method for producing isocyanate

Provided are a method for producing a carbamate, said method comprising the following steps (1) and (2), etc.: (1) a step for producing compound (A) having a urea bond by using an organic primary amine having at least one primary amino group per molecule together with carbon dioxide and/or a carbonic acid derivative at a temperature lower than the thermal dissociation temperature of urea bond; and (2) a step for reacting compound (A) with a carbonic acid ester to thereby produce a carbamate.