COATING LIQUID, METHOD FOR MANUFACTURING OPTICAL COMPONENT, AND PHOTOGRAPHIC OPTICAL SYSTEM

A coating liquid including a fluorine-containing organic magnesium compound represented by the following chemical formula (1), a method for manufacturing an optical component having an optical film obtained from the coating liquid, and a photographic optical system are disclosed: 2. The coating liquid according to claim 1 , wherein Ris (CF)CH.3. The coating liquid according to claim 1 , wherein Ris (CF)C.5. The coating liquid according to claim 4 , wherein Ris (CF)CH.6. The coating liquid according to claim 4 , wherein Ris (CF)C.7. A method for manufacturing an optical component having an optical film claim 4 , the method comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'coating the coating liquid according to on a base material to form a film; and'}burning the film.8. The method according to claim 7 , wherein the optical film is made of magnesium fluoride.9. The method according to claim 7 , wherein a temperature for the burning is 150° C. or more and 200° C. or less.10. A photographic optical system claim 7 , wherein light from an object is focused with an optical member manufactured according to the method according to to form an object image. 1. Technical FieldThe present invention relates to a coating liquid, a method for manufacturing an optical component, and a photographic optical system, in particular, an optical component used as a low refractive index material excellent in an antireflection effect.2. Background ArtOn a surface of an optical component constituting an optical instrument, to improve light transmittance, an antireflection film is formed.When, in air, a low refractive index material of which refractive index nc isnc=√ng   (Formula 1)to the refractive index ng of a base material is coated at an optical film thickness of λ/4 to light having a wavelength λ, the refractive index theoretically becomes zero.A general antireflection film is formed by vacuum depositing a material having the refractive index lower than that of a base ...

NOVEL STRUCTURED CATALYST

The present invention relates to novel structured catalysts based on sintered metal fibers (SMF) coated by a basic oxide layer with Pd-nanoparticles, to reactions of organic compounds with hydrogen in the presence of said catalyst and an organic base as well as to vitamins, carotinoids, perfume ingredients, and/or food or feed ingredients prepared by using this reaction. 1. A structured catalyst based on sintered metal fibers (SMF) coated by a basic oxide layer impregnated with Pd-nanoparticles , characterized in that the SMF contains an alloy wherein the alloy is free from Al.2. The catalyst according to wherein the basic oxide layer comprises ZnO or ZnO and AlO.3. The catalyst according to or claim 2 , wherein the alloy is stainless steel.4. The catalyst according to claim 2 , or claim 2 , wherein at least another metal oxide is part of the basic oxide layer claim 2 , preferably claim 2 , Cr claim 2 , Mn claim 2 , Cu or Mg.5. The catalyst according to any of the preceding claims claim 2 , wherein the alloy claim 2 , which is preoxidized.6. The catalyst of any of the preceding to claim 2 , wherein the Pd-nanoparticles are Pd-nanoparticles.7. The catalyst of any of the preceding to claim 2 , wherein a portion of the Pd-nanoparticles are in a PdMphase claim 2 , wherein M is Zn or Zn and Al and optionally Cr claim 2 , Mn claim 2 , Cu and/or Mg claim 2 , and wherein the PdMphase is formed through activation in a hydrogen atmosphere.8. The catalyst of any of the preceding to claim 2 , wherein the Pd-nanoparticles have a size of between 0.5 and 100 nm claim 2 , preferably between 2 and 20 nm claim 2 , more preferably between 5 and 12 nm and most preferably between 7 and 10 nm.9. The catalyst of any of the preceding to claim 2 , containing between 0.001 and 5 wt.-% of Pd nanoparticles claim 2 , preferably between 0.01 and 2 wt.-% more preferably between 0.05 and 1 wt.-% and most preferably between 0.1 and 0.3 wt.-% based on the weight of the catalyst.10. The catalyst of ...

PRODUCTION OF FATTY ACIDS AND DERIVATIVES THEREOF

Compositions and methods for production of fatty alcohols using recombinant microorganisms are provided as well as fatty alcohol compositions produced by such methods. 1. A method of producing a fatty alcohol composition in a recombinant microorganism , comprising the steps of:(a) genetically engineering a microorganism to comprise a nucleic acid sequence encoding a polypeptide having acetyl-CoA carboxylase activity (EC 6.4.1.2), and a nucleic acid sequence encoding a polypeptide having fatty alcohol forming activity, resulting in a recombinant microorganism;(b) culturing the recombinant microorganism in a culture medium containing a carbon source under conditions effective to express the acetyl-CoA carboxylase polypeptide and the polypeptide having fatty alcohol forming activity, wherein a fatty alcohol composition is produced by said cultured recombinant microorganism; and(c) optionally recovering the fatty alcohol composition from the culture medium.2. The method of claim 1 , further comprising genetically engineering said microorganism to comprise at least one nucleic acid sequence encoding a polypeptide having thioesterase activity claim 1 , wherein said thioesterase polypeptide is expressed.3. The method of claim 1 , wherein said polypeptide having fatty alcohol forming activity is (i) a fatty alcohol forming acyl-CoA reductase (FAR claim 1 , EC 1.1.1.*) claim 1 , or (ii) an acyl-CoA reductase (EC 1.2.1.50) and an alcohol dehydrogenase (EC 1.1.1.1).4. The method of claim 2 , wherein said polypeptide having fatty alcohol forming activity is (i) a fatty alcohol forming acyl-CoA reductase (FAR claim 2 , EC 1.1.1.*) claim 2 , or (ii) an acyl-CoA reductase (EC 1.2.1.50) and an alcohol dehydrogenase (EC 1.1.1.1).5. The method of claim 4 , wherein said polypeptide having fatty alcohol forming activity is a fatty alcohol forming acyl-CoA reductase.6. The method of claim 1 , wherein said the fatty alcohol composition comprises one or more of saturated or unsaturated ...

Method for Converting Farnesol to Nerolidol in the Presence of Alpha-Bisabolol

A method for converting farnesol to nerolidol in the presence of alpha-bisabolol including providing or preparing a mixture of alpha-bisabolol, farnesol, and one or more catalysts for selective isomerization of farnesol to nerolidol in the presence of alpha-bisabolol, and converting at least a portion of the farnesol to nerolidol. 1. A method of converting farnesol to nerolidol in the presence of alpha-bisabolol comprising: alpha-bisabolol;', 'farnesol; and', 'one or more catalysts for selective isomerization of farnesol to nerolidol in the presence of alpha-bisabolol; and, 'providing or preparing a mixture comprisingconverting at least a portion of the farnesol to nerolidol.2. The method according to claim 1 , wherein the molar ratio of alpha-bisabolol to farnesol after farnesol has been converted to nerolidol is greater than the molar ratio of alpha-bisabolol to farnesol prior to when farnesol was converted to nerolidol.3. The method according to claim 1 , wherein the mixture has a molar ratio of alpha-bisabolol to farnesol in a range from 15:1 to 1:100.4. The method according to claim 1 , wherein the mixture has a molar ratio of alpha-bisabolol to farnesol in a range from 2:1 to 1:2.5. The method according to claim 1 , wherein after farnesol has been converted to nerolidol the molar ratio of alpha-bisabolol to farnesol is 30:1 or higher.6. The method according to claim 1 , wherein after farnesol has been converted to nerolidol the molar ratio of alpha-bisabolol to farnesol is 80:1 or higher.7. The method according to claim 1 , wherein after farnesol has been converted to nerolidol the molar ratio of alpha-bisabolol to farnesol is 100:1 or higher.8. The method according to claim 1 , wherein at least one of the catalysts for selective isomerization of farnesol to nerolidol in the presence of alpha-bisabolol comprises a compound of a transition metal of groups 5 to 8 of the periodic table.9. The method according to claim 8 , wherein at least one of the catalysts for ...

HIGH PERFORMANCE FRAGRANCE FORMULATION

A method of formulating a high performance fragrance formulation by selecting an effective amount of fragrance ingredients selected from the group consisting of aroma chemicals and essential oils defined according to the following algorithm: 2. The method of wherein at least 40% of the formula by weight is comprised of fragrance ingredients where Ψ is a constant in the range from about 0.0025 Åto about 0.0055 Åand Δ is a constant in the range of from about −0.55 Å to about −1.0 Å.3. The method of wherein at least 5% of the formula is comprised of compounds with a favorable push factor.4. The method of wherein from about 50 to about 90% of the selected fragrance ingredients have Ψ falling within the range from about 0.0025 Åto about 0.0055 Åand Δ falling in the range of from about −0.55 Å to about −1.0 Å.5. The method of wherein about 5% to about 20% of the fragrance ingredients have a favorable push factor.6. The method of wherein the fragrance ingredients with a favorable push factor are selected from the group consisting aldehyde AA claim 4 , aldehyde C10 claim 4 , fenchyl acetate claim 4 , terpineol claim 4 , styryl acetate claim 4 , methyl nonyl ketone claim 4 , linalool claim 4 , dihydromyrcenol claim 4 , menthol claim 4 , linalyl acetate claim 4 , benzyl acetate claim 4 , allyl heptanoate claim 4 , citronellol claim 4 , citronellyl nitrile claim 4 , isobutyl benzoate and citronellal.7. The method of wherein the weighted average of the constant Δ is greater than −0.6 Å.8. A high performance fragrance formulation prepared according to the method of .9. A high performance fragrance formulation prepared according to the method of wherein at least 40% of the formula by weight is comprised of fragrance ingredients where Ψ is a constant within the range from about 0.0025 Åto about 0.0055 Åand Δ is a constant in the range of from about −0.55 Å to about −1.0 Å.10. The high performance fragrance formulation of wherein at least 5% of the formula is comprised of compounds ...

ISOMERISATION CATALYST

The present invention relates to a process for preparing menthol isomers by selective rearrangement of stereoisomers of menthol or mixtures thereof in the presence of ruthenium-containing supported catalysts doped with or comprising alkaline earth metal alkoxides, and to the catalysts themselves. 1. Catalyst comprising ruthenium applied to a support material , the support material being aluminium oxide , characterized in thatthe catalyst comprises at least one alkaline earth metal alkoxylate oris obtainable by reacting a catalyst comprising ruthenium applied to a support material, the support material being aluminium oxide, with at least one alkaline earth metal alkoxylate.2. Catalyst according to claim 1 , characterized in that the aluminium oxide used as the support material has a BET surface area of at least 100 m/g.3. Catalyst according to or claim 1 , characterized in that the ruthenium content is 0.1 to 35% by weight.5. Catalyst according to claim 4 , characterized in that the alkaline earth metal alkoxylates used are those of the formula (I) in whichM is barium.6. Catalyst according to any of to claim 4 , characterized in that the amount of the alkaline earth metal alkoxylate which is used for preparation of the inventive catalyst is selected such that the molar ratio of ruthenium to alkaline earth metal is 30:1 to 1:30.7. Use of the catalysts according to any of to for isomerization of stereoisomers of menthol or mixtures of such stereoisomers.8. Process for isomerizing stereoisomers of menthol or mixtures of such stereoisomers in the presence of a catalyst according to any of to .9. Process according to claim 8 , characterized in that d claim 8 ,l-menthol is prepared by catalytic isomerization of stereoisomers of menthol or mixtures of these stereoisomers.10. Process according to claim 8 , characterized in that(+)-menthol (D-menthol) is isomerized to (−)-neomenthol or(−)-menthol (L-menthol) to (+)-neomenthol or(+)-isomenthol to (−)-neoisomenthol or(−)- ...

PROCESS FOR THE PREPARATION OF MENTHOL

The invention relates to a process for the preparation of 2-isopropyl-5-methylcyclohexanol (menthol) via the hydrogenation of thymol to neomenthol and the subsequent isomerization to give D/L (+/−)-menthol. 1. Process for the preparation of 2-isopropyl-5-methylcyclohexanol (menthol) , characterized in thata) thymol is hydrogenated with hydrogen in the presence of a rhodium catalyst, optionally in the presence of a solvent,b) the resulting neomenthol is separated off from menthol and the neomenthol isolated in b) is converted to menthol by means of at least one ruthenium-containing catalyst in supported or unsupported form.2. Process according to claim 1 , characterized in that hydrogenation in stage a) is carried out at temperatures of from 60′ to 250° C. claim 1 , preferably from 60°-200° C. claim 1 , particularly preferably 60-120° C. and at a pressure of at least 1.1 bar claim 1 , preferably >1.1 to 325 bar claim 1 , particularly preferably 2-100 bar.3. Process according to or claim 1 , characterized in that supported catalysts claim 1 , preferably catalysts supported on AlO claim 1 , are used as ruthenium catalysts.4. Process according to one or more of to claim 1 , characterized in that cyclic claim 1 , branched and unbranched alcohols having 1-10 carbon atoms claim 1 , aliphatic and cyclic ethers having 4-12 carbon atoms and/or aliphatic and cycloaliphatic hydrocarbons having 5-12 carbon atoms claim 1 , preferably methanol claim 1 , ethanol claim 1 , propanol claim 1 , isopropanol claim 1 , isobutanol claim 1 , tetrahydrofuran claim 1 , diethylene glycol dimethyl ether claim 1 , ethylene glycol dimethyl ether claim 1 , tetrahydrofuran claim 1 , 1 claim 1 ,4-dioxane claim 1 , cyclohexane claim 1 , methylcyclohexane claim 1 , cyclooctane claim 1 , hexane claim 1 , heptane and/or petroleum ether claim 1 , are used as solvents.5. Process according to one or more of to claim 1 , characterized in that step c) is carried out at temperatures of from 60°-250° C. claim ...

METAL POWDERDOUS CATALYST COMPRISING A COCRMO-ALLOY

The present invention is related to a new metal powder catalytic system (catalyst) comprising a cobalt/chrome-alloy as a carrier, its production and its use in hydrogenation processes. 1. A powderous catalytic system comprising (i) 55 wt-%-80 wt-%, based on the total weight of the metal alloy, of Co, and', '(ii) 20 wt-%-40 wt-%, based on the total weight of the metal alloy, of Cr, and', '(iii) 2 wt-%-10 wt-%, based on the total weight of the metal alloy, of Mo, and, 'a metal alloy carrier comprising'}wherein the said metal alloyis coated by a metal oxide layer and impregnated with Pd.2. Catalyst according to claim 1 , wherein the metal alloy comprises further metals.3. Catalyst according to claim 1 , wherein the metal alloy comprises carbon.4. Catalyst according to claim 1 , wherein the metal alloy comprises 55 wt-%-70 wt-% claim 1 , based on the total weight of the metal alloy claim 1 , of Co.5. Catalyst according to claim 1 , wherein the metal alloy comprises 20 wt-%-35 wt-% claim 1 , based on the total weight of the metal alloy claim 1 , of Cr.6. Catalyst according to claim 1 , wherein the metal alloy comprises 4 wt-%-10 wt-% claim 1 , based on the total weight of the metal alloy claim 1 , of Mo.7. Catalyst according to claim 1 , wherein the metal oxide layer is basic or amphoteric.8. Catalyst according to claim 1 , wherein the metal oxide layer comprises Zn claim 1 , Cr claim 1 , Mn claim 1 , Cu and/or Al.9. Catalyst according to claim 1 , wherein the oxide layer comprises ZnO and optionally at least one further metal oxide chosen from the group consisting of Cr claim 1 , Mn claim 1 , Mg claim 1 , Cu and Al.10. Catalyst according to claim 1 , wherein the oxide layer comprises ZnO and AlO.11. Catalyst according to comprising between 0.1 wt-% and 50 wt-% claim 1 , based on the total weight of the catalyst claim 1 , of the non acidic metal oxide layer.12. Catalyst according to claim 1 , wherein the metal oxide is mixture of ZnO and AlOin a ratio of 2:1 to 1:2 ( ...

NOVEL ORGANOLEPTIC COMPOUNDS

The present invention relates to novel compounds and their use as fragrance materials. 1. A compound selected from the group consisting of:2-methoxy-6-methyl-octa-1,5-diene;2-methoxy-6-methyl-octa-2,5-diene; anda mixture thereof.2. A fragrance formulation containing an olfactory acceptable amount of a compound selected from the group consisting of:2-methoxy-6-methyl-octa-1,5-diene;2-methoxy-6-methyl-octa-2,5-diene; anda mixture thereof.3. The fragrance formulation of claim 2 , wherein the olfactory acceptable amount is from about 0.005 to about 50 weight percent of the fragrance formulation.4. The fragrance formulation of claim 2 , wherein the olfactory acceptable amount is from about 0.5 to about 25 weight percent of the fragrance formulation.5. The fragrance formulation of claim 2 , wherein the olfactory acceptable amount is from about 1 to about 10 weight percent of the fragrance formulation.6. The fragrance formulation of further comprising a material selected from the group consisting of a polymer claim 2 , an oligomer and an adjuvant.7. The fragrance formulation of claim 6 , wherein the polymer is selected from the group consisting of polyacrylate claim 6 , polyurea claim 6 , polyurethane claim 6 , polyacrylamide claim 6 , polyester claim 6 , polyether claim 6 , polyamide claim 6 , poly(acrylate-co-acrylamide) claim 6 , starch claim 6 , silica claim 6 , gelatin and gum Arabic claim 6 , alginate claim 6 , chitosan claim 6 , polylactide claim 6 , poly(melamine-formaldehyde) claim 6 , poly(urea-formaldehyde) claim 6 , and a combination thereof.8. A method of improving claim 6 , enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of a compound selected from the group consisting of:2-methoxy-6-methyl-octa-1,5-diene;2-methoxy-6-methyl-octa-2,5-diene; anda mixture thereof.9. The method of claim 8 , wherein the olfactory acceptable amount is from about 0.005 to about 50 weight percent of the fragrance formulation.10. ...

Method for Preparing Crosslinker Compound

The present disclosure relates to a method for preparing a crosslinker compound in which a crosslinker compound capable of using for the production of a super absorbent polymer can be obtained in a higher yield by a simple manner. The crosslinker compound obtained by the above method can be used as a thermally decomposable crosslinker in the process of producing a super absorbent polymer.

DODECA-4,8,11-TRIEN-1-OL AND ITS USE AS AROMA CHEMICAL

The present invention relates to dodeca-4,8,11-trien-1-ol and a method of preparing same, to the use of dodeca-4,8,11-trien-1-ol as aroma chemical; to the use of dodeca-4,8,11-trien-1-ol for preparing an aroma chemical composition or for modifying the aroma character of an aroma chemical composition; to an aroma chemical composition containing dodeca-4,8,11-trien-1-ol; and to a method of preparing an aromatized composition or for modifying the aroma character of an aromatized composition. 1. A compound which is dodeca-4 ,8 ,11-trien-1-ol.2. The compound of which is selected from the group consisting of (4Z claim 1 ,8E)-dodeca-4 claim 1 ,8 claim 1 ,11-trien-1-ol claim 1 , (4E claim 1 ,8Z)-dodeca-4 claim 1 ,8 claim 1 ,11-trien-1-ol claim 1 , (4E claim 1 ,8E)-dodeca-4 claim 1 ,8 claim 1 ,11-trien-1-ol claim 1 , (4Z claim 1 ,8Z)-dodeca-4 claim 1 ,8 claim 1 ,11-trien-1-ol claim 1 , and mixtures of two or more thereof.3. The compound of which is (4Z claim 2 ,8E)-dodeca-4 claim 2 ,8 claim 2 ,11-trien-1-ol.4. The compound of which is (4E claim 2 ,8Z)-dodeca-4 claim 2 ,8 claim 2 ,11-trien-1-ol.5. The compound of which is a mixture of stereoisomers comprising (4Z claim 2 ,8E)-dodeca-4 claim 2 ,8 claim 2 ,11-trien-1-ol and (4E claim 2 ,8Z)-dodeca-4 claim 2 ,8 claim 2 ,11-trien-1-ol.6. The compound of claim 5 , where (4Z claim 5 ,8E)-dodeca-4 claim 5 ,8 claim 5 ,11-trien-1-ol and (4E claim 5 ,8Z)-dodeca-4 claim 5 ,8 claim 5 ,11-trien-1-ol are present in a molar ratio of from 10:1.7. The compound of claim 5 , wherein the mixture further comprises (4E claim 5 ,8E)-dodeca-4 claim 5 ,8 claim 5 ,11-trien-1-ol claim 5 , or (4Z claim 5 ,8Z)-dodeca-4 claim 5 ,8 claim 5 ,11-trien-1-ol claim 5 , or both (4E claim 5 ,8E)-dodeca-4 claim 5 ,8 claim 5 ,11-trien-1-ol and (4Z claim 5 ,8Z)-dodeca-4 claim 5 ,8 claim 5 ,11-trien-1-ol.8. Aroma chemical composition comprising the compound of :(i) at least one additional aroma chemical different from dodeca-4,8,11-trien-1-ol, or(ii) at least one non ...

PERFUME

Inventive subject matter disclosed herein includes a perfume that includes water; alcohol; oil in a concentration of about 2 to 20% by weight; a scent imparting constituent; and a stabilizing agent in a concentration effective for imparting a capacity to make a misting spray pattern when the perfume is sprayed through a sprayer. 129.-. (canceled)31. A hydro-alcoholic perfume , consisting of:Alcohol;Water;Fragrance oil comprising one or more scent imparting constituents; andAn opacifying agent comprising styrene/acrylates copolymer, wherein the hydro-alcoholic perfume is opaque.33. A hydro-alcoholic perfume , consisting of:Alcohol;Water;Fragrance oil comprising one or more scent imparting constituents; andAn opacifying agent comprising styrene/acrylates copolymer, wherein the hydro-alcoholic perfume is opaque, andone or more of an antioxidant, a solvent, an ultraviolet inhibitor, and a quencher.35. A hydro-alcoholic perfume , consisting of:Alcohol;Water;Fragrance oil comprising one or more scent imparting constituents; andAn opacifying agent comprising styrene/acrylates copolymer, wherein the hydro-alcoholic perfume is opaque, andone or more of an antioxidant, a solvent, an ultraviolet inhibitor, and a quencher; anda coloring agent.3640.-. (canceled) This application claims the priority of U.S. provisional application Ser. No. 61/509,364, filed Jul. 19, 2011 and 61/511,288, filed Jul. 25, 2011, which are incorporated herein by reference in their entireties.Inventive subject matter disclosed herein relates to perfume embodiments that include one or more of a perfume oil or essential oil, one or more alcohols, a stabilizing agent and, for some embodiments, a stable suspension of particles.Human beings have been applying fragrances to themselves for thousands of years. The ancient Egyptians, believed to be among the first users, applied perfumed oil and incense to themselves. Some of the earliest recorded chemists made perfume and used the process of distillation to ...

NOVEL CRYSTALLINE SALTS OF ASENAPINE WITH ORGANIC DI-ACIDS AND TRI-ACIDS

Novel crystalline salts of Asenapine (I) with organic di-acids and tri-acids and to methods of their preparation are disclosed along with related pharmaceutical compositions and methods of treating psychotic diseases or disorders. 1. A crystalline polymorphically stable salt , preferably in anhydrous form , of trans-5-chloro-2-methyl-2 ,3 ,3a ,12b-tetrahydro-1 H-dibenz[2 ,3:6 ,7] oxepino[4 ,5-c]pyrrole (Asenapine) with an organic di-acid or tri-acid , wherein said salt has a solubility in water at 25° C. of more than 2.0 mg/ml , calculated as free base and wherein the polymorphic stability is such that at least 90 wt. % of said salt maintains its crystal form upon stirring in acetonitrile for 96 hours at a temperature of 20° C.2. The crystalline salt of claim 1 , wherein the molar ratio of Asenapine to the organic di-acid or tri-acid in said salt is between 1:1.3 to 1.3:1.3. The crystalline salt of claim 1 , wherein the organic di-acid or tri-acid is a carboxylic di-acid or carboxylic tri-acid.4. The crystalline salt of claim 1 , wherein the organic di-acid or tri-acid is malonic acid or citric acid.5. A crystalline salt of Asenapine preferably according to claim 1 , which comprises (i) crystalline Asenapine malonate form I and/or (ii) crystalline Asenapine citrate form I claim 1 , wherein(i) crystalline Asenapine malonate form I is characterized by X-ray powder diffraction reflections (Cu Kα radiation) comprising peaks at two theta angles of about 19.5°±0.2°, 23.7°±0.2°, 8.5°±0.2°, 23.1°±0.2°, and 24.2°±0.2°, and(ii) crystalline Asenapine citrate form I is characterized by X-ray powder diffraction reflections (Cu Ka radiation) comprising peaks at two theta angles of about 15.5°±0.2°, 15.3°±0.2°, 12.6°±0.2°, 23.2°±0.2°, and 19.4°±0.2°.6. A process for preparing a crystalline polymorphically stable salt according to comprising the steps of:a) combining Asenapine free base with an organic di-acid or tri-acid in an organic solvent or organic solvent mixture, optionally ...

Method for producing gamma, delta-unsaturated alcohol

the method including a step of bringing the α-olefin into contact with an aqueous formaldehyde solution in the presence of an alcohol having 3 to 10 carbon atoms, with the aqueous formaldehyde solution being subjected to preheating at 30 to 220° C. before the step.

FRAGRANCE AND FLAVOR MATERIALS

The present disclosure is directed to the synthesis and application of undecavertol derivatives having unique and desired flavor and/or fragrant characteristics. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The present disclosure is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions. 4. (canceled)5. A fragrance or flavor composition comprising one or more compounds of .6. A consumer product containing the flavor or fragrance composition of .7. A fragrance or flavor composition comprising one or more compounds of .8. A fragrance or flavor composition comprising one or more compounds of .9. A consumer product containing the flavor or fragrance composition of .10. A consumer product containing the flavor or fragrance composition of . The present application claims priority to U.S. Provisional Application No. 62/438,374, filed on Dec. 22, 2016, the content of which is incorporated herein by reference in its entirety.The present application relates to compounds useful as fragrance or flavor components in fragrance or flavor compositions.There is a continuing interest in the preparation of synthetic fragrance and flavor components and their use in consumer products. One strategy to prepare such compounds is to apply a known synthetic chemical reaction to readily available substrates. The Claisen Rearrangement is a reaction known to one skilled in the art of organic synthesis. When an allylic alcohol is converted to the vinyl ether and treated with acid and heat, the vinyl ether rearranges to a 4-alkenal. There are several Claisen products known for their use in the flavor and fragrance industry (Nowicki, Molecules 2000, 1033-1050). A similar rearrangement is the Johnson Rearrangement, also known to one skilled in the art, whereby an allylic alcohol is converted to a 4-alkenoic ester.There remains a need and demand for ...

1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF

The disclosure relates to the field of specialty chemicals. In particular, the disclosure provides novel 1,3-fatty-diol compounds and derivatives thereof which are useful e.g., in the production of personal care products, surfactants, detergents, polymers, paints, coatings, and as emulsifiers, emollients, and thickeners in cosmetics and foods, as industrial solvents and plasticizers, etc. 2. The fatty-diol of claim 1 , wherein the double bond is in (Z) configuration.3. The fatty-diol of claim 1 , wherein the double bond is in (E) configuration.4. The fatty-diol of claim 1 , wherein the chiral center at C-3 has an R configuration.5. The fatty-diol of claim 1 , wherein the chiral center at C-3 has an S configuration.6. The fatty-diol of claim 1 , wherein the double bond is in (Z) configuration and wherein the chiral center at C-3 has an R configuration.8. The fatty-diol of claim 7 , wherein the double bond is in (Z) configuration.9. The fatty-diol of claim 7 , wherein the double bond is in (E) configuration.10. The fatty-diol of claim 7 , wherein the chiral center at C-3 has an R configuration.11. The fatty-diol of claim 7 , wherein the chiral center at C-3 has an S configuration.12. The fatty-diol of claim 7 , wherein the double bond is in (Z) configuration and wherein the chiral center at C-3 has an R configuration. This application claims the benefit of U.S. Provisional Application No. 62/394,537 filed Sep. 14, 2016, which is herein incorporated by reference in its entirety.The disclosure relates generally to the field of specialty chemicals suitable for use as components of industrial agents and processes, e.g., in the production of detergents and surfactants, as emulsifiers, emollients, and thickeners in cosmetics and foods, as industrial solvents and plasticizers, etc.Fatty-alcohols, particularly fatty-diols (or aliphatic diols) are amphipathic molecules having many commercial and industrial uses. For example, fatty alcohols find use as emollients and thickeners ...

Process for Preparing Terpinene-4-ol

The present invention relates to a process for preparing terpinene-4-ol from limonene-4-ol via a hydrogenation reaction in the presence of a nickel catalyst. 115-. (canceled)17. The process of claim 16 , wherein the nickel catalyst comprises Raney nickel.18. The process of claim 16 , wherein the carboxylic acid ester is selected from esters of the general formula RCOORwherein Ris hydrogen or selected from the group consisting of C-C-alkyl claim 16 , C-C-cycloalkyl claim 16 , C-C-aryl and C-C-aryl-C-C-alkyl and Ris selected from the group consisting of C-C-alkyl claim 16 , C-C-cycloalkyl claim 16 , C-C-aryl and C-C-aryl-C-C-alkyl claim 16 , each of the aforementioned groups optionally being substituted with one or more substituents selected from C-C-alkoxy.19. The process of claim 16 , wherein the carboxylic acid ester is selected from C-C-alkyl acetates.20. The process of claim 16 , wherein the carboxylic acid ester is ethyl acetate.21. The process of claim 16 , wherein the temperature is from 35 to 70° C.22. The process of claim 16 , wherein the hydrogen overpressure is from 10 mbar to 3 bar.24. The process of claim 23 , wherein terpinolene epoxide of the formula (III) is further subjected to hydrogenation.25. The process of claim 23 , wherein the isomerization and/or hydrogenation are carried out in the presence of at least one copper catalyst.26. The process claim 23 , wherein the isomerization and/or hydrogenation are carried out in the presence of at least one inert organic solvent selected from carboxylic acid esters.27. The process of claim 26 , wherein a mixture comprising limonene-4-ol of the formula (I) claim 26 , terpinene-4-ol of the formula (II) and the at least one inert organic solvent selected from carboxylic acid esters is obtained.28. The process of claim 16 , wherein terpinene-4-ol of the formula (II) is further converted into (±)-2-exo-(2-Methylbenzyloxy)-1-methyl-4-isopropyl-7-oxabicyclo[2.2.1]heptane claim 16 , any of its individual enantiomers ...

Chromium-Catalyzed Production of Diols From Olefins

Processes for converting an olefin reactant into a diol compound are disclosed, and these processes include the steps of contacting the olefin reactant and a supported chromium catalyst comprising chromium in a hexavalent oxidation state to reduce at least a portion of the supported chromium catalyst to form a reduced chromium catalyst, and hydrolyzing the reduced chromium catalyst to form a reaction product comprising the diol compound. While being contacted, the olefin reactant and the supported chromium catalyst can be irradiated with a light beam at a wavelength in the UV-visible spectrum. Optionally, these processes can further comprise a step of calcining at least a portion of the reduced chromium catalyst to regenerate the supported chromium catalyst. 1. A process for converting an olefin reactant into a diol compound , the process comprising:(i) irradiating the olefin reactant and a supported chromium catalyst comprising chromium in a hexavalent oxidation state with a light beam at a wavelength in the UV-visible spectrum to reduce at least a portion of the supported chromium catalyst to form a reduced chromium catalyst; and(ii) hydrolyzing the reduced chromium catalyst to form a reaction product comprising the diol compound.2. The process of claim 1 , wherein the olefin reactant comprises a Cto Clinear claim 1 , branched claim 1 , or cyclic olefin compound.3. The process of claim 1 , wherein the olefin reactant comprises ethylene claim 1 , propylene claim 1 , butene claim 1 , pentene claim 1 , hexene claim 1 , heptene claim 1 , octene claim 1 , decene claim 1 , dodecene claim 1 , tetradecene claim 1 , hexadecene claim 1 , octadecene claim 1 , or any combination thereof.4. The process of claim 1 , wherein the supported chromium catalyst contains from about 0.01 to about 50 wt. % of chromium claim 1 , based on the weight of the supported chromium catalyst.5. The process of claim 1 , wherein the reduced chromium catalyst contains chromium having an average ...

1,3-Fatty Diol Compounds And Derivatives Thereof

The disclosure relates to the field of specialty chemicals. In particular, the disclosure provides novel 1,3-fatty-diol compounds and derivatives thereof which are useful e.g., in the production of personal care products, surfactants, detergents, polymers, paints, coatings, and as emulsifiers, emollients, and thickeners in cosmetics and foods, as industrial solvents and plasticizers, etc. 2. The fatty-diol of claim 1 , wherein the double bond is in (Z) configuration.3. The fatty-diol of claim 1 , wherein the double bond is in (E) configuration.4. The fatty-diol of claim 1 , wherein the chiral center at C-3 has an R configuration.5. The fatty-diol of claim 1 , wherein the chiral center at C-3 has an S configuration.6. The fatty-diol of claim 1 , wherein the double bond is in (Z) configuration and wherein the chiral center at C-3 has an R configuration.712.-. (canceled)14. The compound of claim 13 , wherein Rand Rare not both H.15. The compound of claim 13 , wherein neither Rnor Rare H.16. The compound of claim 13 , wherein the disaccharide claim 13 , trisaccharide claim 13 , or polysaccharide comprises a pentose sugar claim 13 , a hexose sugar claim 13 , or a mixture thereof.17. The compound of claim 16 , wherein the disaccharide claim 16 , trisaccharide claim 16 , or polysaccharide comprises a hexose sugar selected from the group consisting of allose claim 16 , altrose claim 16 , glucose claim 16 , mannose claim 16 , gulose claim 16 , iodose claim 16 , galactose claim 16 , talose claim 16 , and a mixture of any two or more thereof.18. The compound of claim 13 , wherein the disaccharide claim 13 , trisaccharide claim 13 , or polysaccharide comprises a furanose sugar claim 13 , pyranose sugar claim 13 , or a mixture thereof.19. The compound of claim 13 , wherein Rand Rare different monosaccharides.20. The compound of claim 13 , wherein Rand Rare the same monosaccharide.21. A composition comprising the compound of claim 13 , wherein the composition is selected from the ...

PROCESSES FOR PREPARING VINYLIDENE DIMER DERIVATIVES

This disclosure provides a process for producing vinylidene dimer derivatives by subjecting one or more vinylidene dimers and one or more carbonyl-containing compounds to a carbonyl-ene reaction, optionally in the presence of a catalyst, to produce one or more vinylidene dimer derived alcohols. This disclosure also provides a process for producing vinylidene dimer derivatives by reacting one or more vinylidene dimers with one or more carbonyl-containing compounds, optionally in the presence of a catalyst, to produce one or more vinylidene dimer derived alcohols. This disclosure further provides vinylidene dimer derivatives (e.g., vinylidene dimer derived alcohols and esters) produced by these processes. This disclosure still further provides for hydrogenating/reacting the vinylidene dimer derived alcohols with acids or anhydrides to produce vinylidene dimer derived esters. This disclosure yet further relates to lubricating ester oil base stocks, and lubricating oils containing the lubricating ester oil base stocks. 1. A process for producing a composition comprising one or more vinylidene dimer derivatives , said process comprising subjecting one or more vinylidene dimers and one or more carbonyl-containing compounds to a carbonyl-ene reaction , optionally in the presence of a catalyst , under reaction conditions sufficient to produce one or more vinylidene dimer derived alcohols.2. The process of wherein the one or more vinylidene dimers are selected from mPAO dimers (C-C); the one or more carbonyl-containing compounds are selected from aldehydes; andthe at least one catalyst is selected from Lewis acids.3. The process of wherein the Lewis acids are selected from metal halides claim 2 , metalloid halides claim 2 , molecular sieves claim 2 , and combinations thereof4. The process of which is carried out under reaction conditions sufficient to activate a carbonyl group and scavenge an acidic proton claim 1 , to produce said one or more vinylidene dimer derived ...

COMPOSITIONS COMPRISING HYDROPHOBICALLY MODIFIED POLYAMINE POLYMER COMPATIBLE PERFUME MATERIALS

Compositions comprising hydrophobic ally modified polyamine polymers and hydrophobically modified polyamine polymer compatible perfume materials, more specifically, perfume aldehydes that do not react with hydrophobically modified polyamine polymers are provided. 2. The composition of claim 1 , wherein said R value is about 0.5 to less than 1.3. The composition of claim 1 , wherein said perfume aldehyde component comprises less than about 70% claim 1 , by weight of said perfume aldehyde component claim 1 , of perfume aldehydes having an R value less than 1.4. The composition of claim 1 , wherein said perfume mixture comprises at least one perfume aldehyde selected from the group consisting of: amyl cinnamic aldehyde claim 1 , anisic aldehyde claim 1 , benzaldehyde claim 1 , citronellal claim 1 , cuminic aldehyde claim 1 , citronellal oxyacetaldehyde claim 1 , floralozone claim 1 , heliotropin claim 1 , hexyl cinnamic aldehyde claim 1 , and mixtures thereof.5. The composition of wherein said perfume mixture comprises at least 10% claim 1 , by weight of said perfume mixture claim 1 , of at least one perfume aldehyde selected from the group consisting of: amyl cinnamic aldehyde claim 1 , anisic aldehyde claim 1 , benzaldehyde claim 1 , citronellal claim 1 , cuminic aldehyde claim 1 , citronellal oxyacetaldehyde claim 1 , floralozone claim 1 , heliotropin claim 1 , hexyl cinnamic aldehyde claim 1 , and mixtures thereof.6. The composition of wherein said perfume mixture comprises hexylcinnamic aldehyde and anisic aldehyde.7. The composition of claim 1 , wherein said hydrophobically modified polyamine polymer is present in an amount from about 0.05% to about 0.1% claim 1 , by weight of said composition.8. The composition of claim 1 , wherein said polyamine polymer is selected from the group consisting of: a PVams claim 1 , a PEI claim 1 , a PAMam claim 1 , a PAam claim 1 , a PEam claim 1 , and mixtures thereof.9. The composition of claim 1 , wherein said polyamine polymer ...

NOVEL ORGANOLEPTIC COMPOUNDS

The present invention relates to novel compounds and their use as fragrance materials. 12-methoxy-6-methyl-octa-1,5-diene;2-methoxy-6-methyl-octa-2,5-diene; anda mixture thereof.. A compound selected from the group consisting of: This application is a divisional of U.S. Ser. No. 15/649,682, filed Jul. 14, 2017, now allowed, the contents hereby incorporated by reference as if set forth in its entirety.The present invention relates to new chemical entities and the incorporation and use of the new chemical entities as fragrance materials.There is an ongoing need in the fragrance industry to provide new chemicals to give perfumers and other persons the ability to create new fragrances for perfumes, colognes and personal care products. Those with skill in the art appreciate how differences in the chemical structure of the molecule can result in significant differences in the odor, notes and characteristics of a molecule. These variations and the ongoing need to discover and use the new chemicals in the development of new fragrances allow the perfumers to apply the new compounds in creating new fragrances.The present invention provides novel compounds and their unexpected advantageous use in enhancing, improving or modifying the fragrance of perfumes, colognes, toilet water, fabric care products, personal products and the like.More specifically, an embodiment of the present invention relates to novel compounds represented by Formula I, 2-methoxy-6-methyl-octa-1,5-diene; Formula II, 2-methoxy-6-methyl-octa-2,5-diene; and a mixture thereof which exhibit unexpected herbal, ocean breezy and ozoney notes, and a method of improving, enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of theses compounds.Another embodiment of the present invention relates to a fragrance composition comprising the novel compounds provided above.Another embodiment of the present invention relates to a fragrance product comprising the compounds ...

USE OF DOCASATRIENES, RESOLVINS, AND THEIR STABLE ANALOGS IN THE TREATMENT OF AIRWAY DISEASES AND ASTHMA

The present invention is generally drawn to novel isolated therapeutic agents, termed resolvins, generated from the interaction between a dietary omega-3 polyunsaturated fatty acid (PUFA) such as eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA), cyclooxygenase-II (COX-2) and an analgesic, such as aspirin (ASA). Surprisingly, careful isolation of compounds generated from the combination of components in an appropriate environment provide di- and tri-hydroxy EPA or DHA compounds having unique structural and physiological properties. The present invention therefore provides for many new useful therapeutic di- or tri-hydroxy derivatives of EPA or DHA (resolvins) that diminish, prevent, or eliminate inflammation or PMN migration, for example. The present invention also provides methods of use, methods of preparation, and packaged pharmaceuticals for use as medicaments for the compounds disclosed throughout the specification. 2. A method to treat or prevent inflammation in a subject comprising the step of administering to the subject a therapeutically effective amount of an isolated compound of claim 1 , wherein inflammation is treated or prevented.3. A composition comprising an isolated compound of and a pharmaceutically acceptable carrier.4. A method to treat or prevent inflammation in a subject comprising the step of administering to the subject a therapeutically effective amount of the composition of claim 3 , wherein inflammation is treated or prevented.5. The isolated compound of claim 1 , wherein the chiral carbon atom at the 7 position (C-7) has an S configuration and Ris a hydrogen atom.6. A method to treat or prevent inflammation in a subject comprising the step of administering to the subject a therapeutically effective amount of an isolated compound of claim 5 , wherein inflammation is treated or prevented.7. A composition comprising an isolated compound of and a pharmaceutically acceptable carrier.8. A method to treat or prevent inflammation in a ...

METHODS AND COMPOSITIONS FOR IMPROVED PRODUCTION OF FATTY ACIDS AND DERIVATIVES THEREOF

The invention relates to compositions and methods, including polynucleotide sequences, amino acid sequences, and engineered host cells for producing fatty acids and derivates of fatty acids such as acyl-CoA, terminal olefins, fatty aldehydes, fatty alcohols, alkanes, alkenes, wax esters, ketones and internal olefins through altered expression of the transcription factor, fadR. 1. A method of producing a fatty acid or derivative thereof , comprising:(a) providing a host cell which is genetically engineered to have an altered level of expression of a FadR polypeptide as compared to the level of expression of the FadR polypeptide in a corresponding wild-type host cell,(b) culturing the engineered host cell in a culture medium under conditions permissive for the production of a fatty acid or derivative thereof, and(c) isolating the fatty acid or derivative thereof from the engineered host cell, wherein one or more of the titer, yield, or productivity of the fatty acid or derivative thereof produced by the engineered host cell is increased relative to that of the corresponding wild-type host cell.2. The method of claim 1 , wherein the altered level of expression of the FadR polypeptide in the engineered host cell is increased as compared to the level of expression of the FadR polypeptide in the corresponding wild-type host cell.3Escherichia, Salmonella, Citrobacter, Enterobacter, Klebsiella, Cronobacter, Yersinia, Serratia, Erwinia, Pectobacterium, Photorhabdus, Edwardsiella, ShewanellaVibrio.. The method of claim 1 , wherein the FadR polypeptide is encoded by a fadR gene obtained from claim 1 , or4. The method of claim 1 , wherein the FadR polypeptide is a wild-type FadR polypeptide.5. The method of claim 1 , wherein the FadR polypeptide is a mutant FadR polypeptide.6. The method of claim 5 , wherein the FadR polypeptide comprises a mutation at amino acid 219 of SEQ ID NO: 1.7. The method of claim 6 , wherein the mutation is a substitution of the amino acid 219 of SEQ ...

PERFUME COMPOSITIONS

A perfume composition having controlled release of phytoncides in an atmosphere in order to generate an air condition resembling the air environment of a forest is provided. The perfume composition includes a) at least about 0.6% by weight of at least one phytoncide; and b) a perfume mixture including (i) at least one solvent; and (ii) at least one fragrance ingredient. At least about 25% by weight of the at least one phytoncide is selected from the group consisting of pinene alpha, pinene beta and combinations thereof. 1. A perfume composition having controlled release of phytoncides in an atmosphere comprising:a) at least about 0.6% by weight of at least one phytoncide, wherein at least about 25% by weight of the at least one phytoncide is selected from the group consisting of pinene alpha, pinene beta and combinations thereof; and{'sub': i', 'i, 'sup': 0', '0, 'b) a perfume mixture including (i) at least one solvent; and (ii) at least one fragrance ingredient, wherein said perfume mixture exhibits a Equilibrium Headspace Concentration (HS) distribution curve having greater than about 95 wt % of the perfume mixture exhibiting HSof less than or equal to about 10,000 μg/L.'}2. The perfume composition according to claim 1 , wherein the perfume mixture exhibits a Standard Equilibrium Headspace Concentration (HS) distribution curve from about 40 wt % to about 85 wt % of the perfume mixture exhibiting HSof less than or equal to about 1 claim 1 ,000 μg/L; from about 20 wt % to about 75 wt % of the perfume mixture exhibiting HS0 of less than or equal to about 300 μg/L; and from about 5 wt % to about 50 wt % of the perfume mixture exhibiting a HSof less than or equal to about 100 μg/L.3. The perfume composition according to claim 1 , wherein at least 35% of the at least one phytoncide is selected from the group consisting of pinene alpha claim 1 , pinene beta and combinations thereof.4. The perfume composition according to claim 1 , further comprising one or more ...

METHODS OF MAKING 15-HYDROXY FATTY ACID DERIVATIVES

The present disclosure provides methods of making 15-hydroxy fatty acid derivatives, such as 15-(S)-hydroxyeicosatrienoic acid (HETrE or 15-(S)-HETrE) or 15(S)-hydroxyeicosapentaenoic acid (HEPE or 15(S)-HEPE) from the corresponding fatty acid (e.g., dihomo-γ-linolenic acid (DGLA) or eicosapentaenoic acid (EPA), respectively). In some embodiments, the method comprises contacting the fatty acid with an oxidizing agent (e.g., a lipoxygenase and oxygen) in the presence of a reducing agent (e.g., cysteine) to form the 15-hydroxy fatty acid derivatives in a single reaction vessel. 1. A process for the production of 15-hydroxy derivatives of fatty acids wherein cysteine is used as the reducing agent.2. The process according to claim 1 , wherein less than 400 Munits per gram of the fatty acid is used in the reaction.3. The process according to claim 1 , wherein the yield is at least about 50%.4. The process of claim 1 , wherein the 15-hydroxy derivative is 15(S)-HETrE.5. The process of comprising oxidizing the fatty acid to form a 15-hydroperoxy fatty acid intermediate and reducing the intermediate to form the 15-hydroxy derivative.6. The process of claim 1 , wherein the 15-hydroxy derivative is 15(S)-hydroxyeicosapentaenoic acid This application claims priority to U.S. Provisional Patent Application Ser. No. 61/896,901, filed Oct. 29, 2013, the entire contents of which are incorporated herein and relied upon.The present disclosure provides a two-step process for the production of 15-hydroxy fatty acid derivatives, such as 15-(S)-hydroxyeicosatrienoic acid (HETrE or 15-(S)-HETrE) or 15(S)-hydroxyeicosapentaenoic acid (HEPE or 15(S)-HEPE) starting from the corresponding fatty acid (e.g., dihomo-y-linolenic acid (DGLA) or eicosapentaenoic acid (EPA), respectively). The first step involves the enzymatic oxidation of the fatty acid to a 15(S)-hydroperoxide fatty acid intermediate (e.g., using a liquid enzyme formulation), followed by reduction to the 15(S)-hydroxy fatty acid ...

Use of 4,8 dimethyl-3,7 nonadien-2-ol as fragrance

4,8-Dimethyl-3,7-nonadien-2-ol in which the weight ratio of (E)-4,8-dimethyl-3,7-nonadien-2-ol to the sum of (E)- and (Z)-4,8-dimethyl-3,7-nonadien-2-ol is at least 80% or in which the weight ratio of (Z)-4,8-dimethyl-3,7-nonadien-2-ol to the sum of (E)- and (Z)-4,8-dimethyl-3,7-nonadien-2-ol is at least 80%, is used as fragrance. The fragrances have a unique rose-like, floral character. Citrus-like, minty, green accompanying notes reminiscent of rhubarb arise.

Fragrance-Containing Cyclodextrin-Based Metal Organic Frameworks

This disclosure relates to a composition containing a fragrance and a porous cyclodextrin-based metal organic framework (CD-MOF). The CD-MOF includes at least a metal cation and a plurality of cyclodextrin molecules. 1. A composition , comprising:a fragrance; anda porous cyclodextrin-based metal organic framework (CD-MOF), the CD-MOF comprising at least a metal cation and a plurality of cyclodextrin molecules;wherein the composition comprises from about 0.01 μL to about 10 μL of the fragrance per 1 mg of the CD-MOF.2. The composition of claim 1 , wherein the composition comprises from about 0.1 μL to about 5 μL of the fragrance per 1 mg of the CD-MOF.3. The composition of claim 1 , wherein the composition comprises from about 0.5 μL to about 2 μL of the fragrance per 1 mg of the CD-MOF.4. The composition of claim 1 , wherein the CD-MOF has an average particle size of from about 10 nm to about 1 μm.5. The composition of claim 1 , wherein the CD-MOF has an average particle size of from about 1 μm to about 1 cm.6. The composition of claim 1 , further comprising a carrier that is an oil or an organic solvent.7. The composition of claim 1 , further comprising a carrier that is an aqueous solvent and the composition of the fragrance and the CD-MOF is at least about 50 wt % to at most about 90 wt % of the carrier.8. The composition of claim 1 , further comprising a fixative.9. The composition of claim 8 , wherein the fixative comprises an ester claim 8 , an alcohol claim 8 , a ketone claim 8 , a resin claim 8 , or a musk.10. A composition claim 8 , comprising:a first component comprising a first porous cyclodextrin-based metal organic framework (CD-MOF) and a first fragrance, the first CD-MOF comprising at least a first metal cation and a plurality of first cyclodextrin molecules; anda second component comprising a second CD-MOF and a second fragrance, the second CD-MOF comprising at least a second metal cation and a plurality of second cyclodextrin molecules;wherein the ...

OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME

An odorant mixture is disclosed. The odorant mixture comprises N odorant components wherein N equals at least 20. Each odorant component is characterized by a multidimensional vector of attributes. A z score of an average of characteristic distances between vectors corresponding to odorant components in the mixture and vectors corresponding to odorant components in a group of M odorant components but not in the mixture is less than 2. 1. An odorant mixture , comprising N odorant components wherein N equals at least 20 , each odorant component being characterized by a multidimensional vector of attributes , such that the mixture is characterized by N respective multidimensional vectors ,wherein a z score of an average of characteristic distances between vectors corresponding to odorant components in the mixture and vectors corresponding to odorant components in a group of M odorant components but not in the mixture is less than 2.2. The odorant mixture according to claim 1 , wherein at least a portion of said N odorant components is selected from said group of M odorant components.3. The odorant mixture according to claim 1 , wherein M is at least equal to N.4. The odorant mixture according to claim 1 , wherein said N odorant components have similar odor intensity.5. The odorant mixture according to claim 1 , wherein each characteristic distance is defined as a minimum distance between a vector corresponding to odorant components in the mixture and a vector corresponding to an odorant component in said group of M odorant components but not in the mixture.6. The odorant mixture according to claim 1 , wherein each of said multidimensional vectors has at least 50 dimensions.7. (canceled)8. (canceled)9. The odorant mixture according to claim 1 , wherein N equals at least 30.1013-. (canceled)14. The odorant mixture according to claim 1 , wherein said group of M odorant components is selected from the odorant components listed in Table A.1 or Table A.2 of Annex 1.15. The ...

SYNTHESIS OF ALIPHATIC ALCOHOLS AS AROMA CHEMICALS

The present invention relates to a method for preparing a compound of formula (I). The present invention also relates to compounds of formula (A) or a compound in the form of a stereoisomer. The present invention further relates to the use of a compound of formula (A) as aroma chemical. 3. The process according to the claim 1 , wherein steps (b) claim 1 , (c) and (d) and/or steps (b) and (c) and/or steps (c) and (d) are carried out in a single pot.4. The process according to the claim 1 , wherein the peroxyacid in step b) is selected from the group consisting of peroxymonosulfuric acid claim 1 , peroxyphosphoric acid claim 1 , peroxyacetic acid claim 1 , peroxyformic acid claim 1 , peroxytrifluoroacetic acid claim 1 , potassium peroxymonosulfate claim 1 , sodium perborate claim 1 , peroxynitric acid and peroxybenzoic acid.5. The process according to the claim 4 , wherein the peroxybenzoic acid is meta-chloroperoxybenzoic acid.6. The process according to the claim 1 , wherein the peroxide in step b) is selected from the group consisting of hydrogen peroxide.7. The process according to claim 1 , wherein step d) is carried out in the presence of an acid.8. The process according to claim 7 , wherein the acid is selected from the group consisting of methanesulfonic acid claim 7 , phosphoric acid claim 7 , p-toluenesulfonic acid claim 7 , formic acid claim 7 , sulfuric acid claim 7 , hydrochloric acid and acetic acid.10. The compound of claim 9 , wherein Ris H or methyl;{'sup': 2', '5, 'Ris selected from the group consisting of H, methyl, ethyl, 1-propyl, 1-methylethyl, and cyclopropyl; Ris selected from the group consisting of methyl, ethyl, 1-propyl, 1-methylethyl, and cyclopropyl;'}{'sup': '4', 'Ris selected from the group consisting of H, ethyl, 1-propyl, 1-methylethyl, and cyclopropyl;'}{'sup': '3', 'and Ris H.'}12. A composition comprising at least one compound selected from the the mixture of compounds of the formulae (A.a) claim 9 , (A.b) and (A.c) according to . ...

Method for Preparing High-Content Zeaxanthin

The invention discloses a method for preparing high-content zeaxanthin. In the conventional preparation methods, some methods adopt certain toxic organic solvents; some methods require the multi-step crystallization process; and some methods are featured by long reaction time, high temperature and lower product yield, thus being not suitable for industrial production. The invention adopts lutein crystal or its fatty acid ester as the raw material and utilizes isomerization reaction to produce zeaxanthin, and is characterized in that a mixed catalyst consisting of an organic base catalyst and a cocatalyst is used in the isomerization reaction, wherein the cocatalyst is palladium carbon. The invention has the advantages of simple process route, low reaction temperature, short reaction time, good product purity and high yield, thus being suitable for industrial production, and no poisonous and harmful organic solvent residues in the product, thus being suitable for the use as a food additive or drug. 1. A method for preparing high-content zeaxanthin , which adopts lutein crystals or its fatty acid esters as the raw material and utilizes isomerization reaction to obtain zeaxanthin , and is characterized in that a mixed catalyst consisting of an organic base catalyst and a cocatalyst is used in the isomerization reaction , and the cocatalyst is palladium carbon.2. The method for preparing high-content zeaxanthin of is characterized in that the specific steps of the method are as follows:{'b': '1', '{circle around ()} Add lutein crystals or its fatty acid esters as the reaction raw material in an organic solvent, to be sufficiently dissolved at a temperature of 60-95° C. ;'}{'b': 2', '1, '{circle around ()} Add an organic base catalyst and a cocatalyst into the mixed solution obtained in Step {circle around ()} to carry out isomerization reaction, wherein the organic base catalyst is added dropwise;'}{'b': '3', '{circle around ()} Perform incubated reaction under nitrogen ...

Novel Ethynylation Catalyst And Method Of Making Same

A novel catalyst useful in the ethynylation of formaldehyde to butynediol is formed by precipitating copper and bismuth from a salt solution of such metals, utilizing an alkali metal hydroxide as the precipitating agent to deposit copper and bismuth hydroxide as a coating around a siliceous carrier particle. 1. A method of preparing a catalyst for the ethynylation of formaldehyde which comprises: depositing by precipitation copper hydroxide , over a particulate siliceous carrier and calcining the treated carrier to yield a copper oxide coating around the carrier.2. The method of claim 1 , wherein a mixture of copper and bismuth hydroxides are deposited on said carrier.3. The method of claim 1 , wherein the copper hydroxide is formed by adding an alkali metal hydroxide to an acidic copper salt solution.4. The method of claim 3 , wherein an acidic solution is made of a mixture of copper nitrate and bismuth nitrate.5. The method of claim 3 , wherein said alkali metal hydroxide is sodium hydroxide.6. The method of claim 5 , wherein the sodium hydroxide is provided in a separate vessel from the acidic solution claim 5 , and the siliceous carrier particles are provided in water in a precipitation vessel separate from the sodium hydroxide and acidic solution.7. The method of claim 6 , wherein the acidic solution and the sodium hydroxide are added simultaneously to the precipitation vessel.8. The method of claim 6 , wherein the precipitation is carried out at a constant pH of between about 6 to about 10.9. The method of claim 6 , wherein the precipitation is carried out at a contrast pH of between 7.5 to 9.5.10. The method of claim 6 , wherein the precipitation is carried out at a temperature of about 40° C. to 90° C.11. The method of claim 10 , wherein the temperature is between 45° C. to 65° C.12. The method of claim 1 , wherein the precipitate is filtered claim 1 , washed and dried and the dried material calcined in air at a temperature between about 250 to about 550° C. ...

FLAVOR AND FRAGRANCE FORMULATION (IV)

The present invention relates to the use of specific organic compounds as flavor and fragrance material. Furthermore the invention relates to new specific organic compounds, as well as to flavor and fragrance formulations comprising at least one of the specific organic compounds. 4. Use according to claim 1 , wherein at least one compound selected from the group consisting of compounds of formulae (II) claim 1 , (V) claim 1 , (VI) and (VII) is used.7. Flavor and fragrance formulation according to comprising 0.0001-10 wt-% claim 5 , related to the total weight of the flavor and fragrance formulation claim 5 , of at least one compound of formula (I).8. Flavor and fragrance formulation according to claim 5 , wherein the flavor and fragrance formulation is solid claim 5 , gel-like or liquid.9. Flavor and fragrance formulation according to claim 5 , wherein the flavor and fragrance formulation is a perfume claim 5 , air care product claim 5 , household product claim 5 , laundry product claim 5 , body care product or cosmetic product. The present invention relates to the use of specific organic compounds as flavor and fragrance material. Furthermore the invention relates to new specific organic compounds, as well as to flavor and fragrance formulations comprising at least one of the specific organic compound.In the flavor and fragrance industry there is always a need and demand for compounds that enhance, modify, improve or otherwise positively influence an odor note and therefore giving perfumers or other persons the ability to create new fragrances for perfumes, colognes, personal care products, household products or any other products, which comprise flavor and fragrance materials.Surprisingly it was found that the compounds of formula (I) are very useful as flavor and fragrance material.Therefore the present invention is related to the use of a compound of formula (I)wherein Rsignifies —H (hydrogen), or —CH(methyl), and Rsignifies a moietyor Rsignifies methyl (=“—CH ...

FRAGRANCE AND FLAVOR MATERIALS

The synthesis and application of compounds having unique and desired flavor and/or fragrance characteristics are provided herein. The compounds herein can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The application is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions. 2. The fragrance or flavor compound of claim 1 ,{'sub': 1', '7, 'wherein Ris H, alkyl or C(O)R;'}{'sub': '2', 'wherein Ris alkyl, alkenyl, alkynyl, linear or branched aryl;'}{'sub': '3', 'wherein Ris H, alkyl, alkenyl, alkynyl, linear or branched aryl;'}{'sub': 4', '2', '6, 'wherein Ris H, C-Calkyl, alkenyl, alkynyl, linear or branched aryl;'}{'sub': '5', 'wherein Ris H or alkyl;'}{'sub': '6', 'wherein Ris bicyclo[2.2.1]hept-5-enyl; and'}{'sub': '7', 'wherein Ris H, alkyl, alkenyl, alkynyl, linear or branched aryl.'}3. The fragrance or flavor compound of claim 1 ,{'sub': 1', '7, 'wherein Ris H, alkyl or C(O)R;'}{'sub': '2', 'wherein Ris alkyl, alkenyl, alkynyl, linear or branched aryl;'}{'sub': '3', 'wherein Ris H, alkyl, alkenyl, alkynyl, linear or branched aryl;'}{'sub': '4', 'wherein Ris alkyl, alkenyl, alkynyl, linear or branched aryl;'}{'sub': '5', 'wherein Ris H or alkyl;'}{'sub': '6', 'wherein Ris cyclohexenyl; and'}{'sub': '7', 'wherein Ris H, alkyl, alkenyl, alkynyl, linear or branched aryl.'}4. The fragrance or flavor compound of claim 1 ,{'sub': 1', '7, 'wherein Ris H, alkyl or C(O)R;'}{'sub': 2', '2', '6, 'wherein Ris H, C-Calkyl, alkenyl, alkynyl, linear or branched aryl;'}{'sub': '3', 'wherein Ris H, alkyl, alkenyl, alkynyl, linear or branched aryl;'}{'sub': 4', '2', '6, 'wherein Ris H, C-Calkyl, alkenyl, alkynyl, linear or branched aryl;'}{'sub': '5', 'wherein Ris H or alkyl;'}{'sub': '6', 'wherein Ris cyclohexenyl; and'}{'sub': '7', 'wherein Ris H, alkyl, alkenyl, alkynyl, linear or branched aryl.'}5. The fragrance or flavor compound of claim 1 ,{'sub': 1', '7, 'wherein Ris ...

METHOD FOR PRODUCING 3,7-DIMETHYL-7-OCTENOL AND METHOD FOR PRODUCING 3,7-DIMETHYL-7-OCTENYL CARBOXYLATE COMPOUND

Methods selectively and efficiently produce 3,7-dimethyl-7-octenol and a carboxylic acid ester thereof. More specifically, a method produces 3,7-dimethyl-7-octenol, including steps of: subjecting a 3-methyl-3-butenyl nucleophilic reagent (2) and a 1,3-dihalo-2-methylpropane compound (3) to a coupling reaction to obtain a 2,6-dimethyl-6-heptenyl halide compound (4); converting the compound (4) into a 2,6-dimethyl-6-heptenyl nucleophilic reagent (5); and subjecting the nucleophilic reagent (5) to an addition reaction with at least one electrophilic reagent selected from the group made of formaldehyde, paraformaldehyde and 1,3,5-trioxane, followed by a hydrolysis reaction to obtain 3,7-dimethyl-7-octenol (6); and the other method. The invention relates to a method for producing 3,7-dimethyl-7-octenol and a method for producing a 3,7-dimethyl-7-octenyl carboxylate compound.3,7-Dimethyl-7-octenol has a rose-like aroma and is widely applied in floral compounded perfumes and fruit flavors.3,7-Dimethyl-7-octenol is commercially available, but a commercial product may be an optically active scalemic mixture which has been separated from natural geranium oil and contains an excess amount of one enantiomer, or may be a mixture containing geraniol (i.e. 3,7-dimethyl-2,6-octadienol), 3,7-dimethyl-6-octanol, or linalool as an impurity. Some commercially available products of 3,7-dimethyl-7-octenol are confused in terms of product names depending on suppliers or raw materials. Products available under the name of rhodinol, cc-citronellol or the like may be a mixture of (S)-3,7-dimethyl-7-octenol or 3,7-dimethyl-6-octenol as a main component with various monoterpene alcohols. Hence, chemically pure 3,7-dimethyl-7-octenol, especially the (+)-3,7-dimethyl-7-octenol, is difficult to obtain, and there is a strong demand for the method for selectively and efficiently synthesizing chemically pure (1)-3,7-dimethyl-7-octenol.3,7-Dimethyl-7-octenyl carboxylates, which are carboxylic acid ...

6-CHROMANOL DERIVATIVES AND THEIR SYNTHESIS

The present invention relates to novel compounds which are particularly useful for the synthesis of novel chromanol derivatives. These compounds have interesting properties. Particularly, the novel chromanol derivatives have interesting antioxidant properties as well as flavours and fragrances. 18. An antioxidant which comprises the compound of formula (I) according to .19. A flavour or fragrance composition which comprises the compound of formula (IV) claim 4 , (VI) claim 4 , (VII) claim 4 , (V) claim 4 , (II-A) or (II-B) according to . The present invention relates to novel compounds which are particularly useful for the synthesis of novel chromanol derivatives.The field of isoprenoids and their derivatives is a field in chemistry, in which a lot of synthesis research has been carried out. One of the reasons is that they are precursors of vitamin E, particularly for alpha-tocopherol, which are very important compounds found in nature and important for the food and feed market. The isoprenoids beta-farnesene and beta-myrcene have been identified in this context as interesting starting compounds. Already more than 30 years ago, Rhône-Poulenc has researched this field intensively, e.g. U.S. Pat. Nos. 4,460,786, 4,621,165 and 5,874,636. CN 105859534 A and WO 2015/165959 A1 disclose beta-farnesene as potential starting material for the synthesis of farnesyl acetone.Myrcene is a compound of natural origin and occurs in significant amounts in essential oil of several plants, including bay, , ylang-ylang, wild thyme, parsley, cardamom, and hops. In addition, it is manufactured from beta-pinene which is obtained from turpentine oil. Therefore, beta-myrcene is a readily available, sustainable, and interesting starting material for synthesis of more complex chemicals.Surprisingly, we have found a whole series of compounds, not known up to now, with very interesting properties, which can be derived from myrcene. In a sequence of different reactions involving these novel ...

2,4,7-trimethyloct-6-en-1-ol as fragance ingredient

2,4,7-Trimethyloct-6-en-1-ol which is useful as a fragrance ingredient.

TERMINAL ALKENE MONOISOMERIZATION CATALYSTS AND METHODS

The invention provides novel catalysts and methods of using catalysts for controlling the position of a double bond and cis/trans-selectivity in isomerization of terminal alkenes to their 2-isomers. Catalysts such as (pentamethylcyclopentadienyl)Ru formulas 1 and 3 having a bifunctional phosphine can be used in the methods. A catalyst loading of 1 mol % of formulas 1+3 can be employed for the production of (E)-2-alkenes at 40-70° C.; lower temperatures can be used with higher catalyst loading. Acetonitrile-free catalysts can be used at lower loadings, room temperature, and in less than a day to accomplish the same results as catalysts 1+3. The novel catalyst systems minimize thermodynamic equilibration of alkene isomers, so that the trans-2-alkenes of both non-functionalized and functionalized alkenes can be generated. 2. The catalyst of wherein Ris iso-propyl claim 1 , iso-butyl claim 1 , tert-butyl or 1-adamantyl.3. The catalyst of wherein Ris alkyl nitrile claim 1 , cycloalkyl nitrile claim 1 , aryl nitrile claim 1 , heteroaryl nitrile claim 1 , heterocycloalkyl nitrile claim 1 , alkylcarbonyl claim 1 , CO claim 1 , alkylamine claim 1 , alkenylamine claim 1 , arylamine claim 1 , amide claim 1 , alkanol claim 1 , water claim 1 , (C-C)-alkenol claim 1 , cycloalkanol claim 1 , aryl alcohol claim 1 , ketone claim 1 , ether claim 1 , aldehyde claim 1 , alkene claim 1 , halo claim 1 , carboxylate claim 1 , sulfonyl claim 1 , sulfonate claim 1 , phosphonyl claim 1 , phosphinyl claim 1 , or N.4. The catalyst of wherein Ris carbonyl claim 3 , CO claim 3 , alkylamine claim 3 , alkenylamine claim 3 , arylamine claim 3 , amide claim 3 , alkanol claim 3 , water claim 3 , (C-C)-alkenol claim 3 , cycloalkanol claim 3 , aryl alcohol claim 3 , ketone claim 3 , ether claim 3 , aldehyde claim 3 , alkene claim 3 , halo claim 3 , carboxylate claim 3 , sulfonyl claim 3 , sulfonate claim 3 , phosphonyl claim 3 , phosphinyl claim 3 , or N.5. The catalyst of wherein Ris acetonitrile ...

SYNTHESIS OF POLYOLS SUITABLE FOR CASTOR OIL REPLACEMENT

A method for the preparation of polyol from an unsaturated TAG oil that can function similarly to castor oil in certain applications. The method comprises controlled epoxidation of the TAG oil with an acid and an oxidizing agent to obtain a partially epoxidized TAG oil with desired iodine and oxirane values; hydroxylating the partially epoxidized TAG oil using a monoalcohol and a solid acid catalyst to obtain the polyol. The resulting polyols are comprised of a triglyceride structure and hydroxyl values, viscosities, and colors that are similar to castor oil. 1. A method for the preparation of polyols from an unsaturated triacylglycerol (TAG) oil , comprising the steps of:(a) partially epoxidizing the unsaturated TAG oil with an acid and an oxidizing agent to obtain a partially epoxidized TAG oil which is still unsaturated; and(b) hydroxylating the partially epoxidized TAG oil using an alcohol and an acid catalyst to obtain hydroxylated and unsaturated TAG polyols.2. The method of claim 1 , wherein the unsaturated TAG oil comprises camelina oil claim 1 , canola oil claim 1 , high oleic canola oil claim 1 , sunflower oil claim 1 , juvenile canola oil claim 1 , flaxseed oil claim 1 , camelina oil claim 1 , solin oil claim 1 , yellow mustard oil claim 1 , brown mustard oil claim 1 , oriental mustard oil claim 1 , palm oil olein claim 1 , or palm oil claim 1 , soy oil claim 1 , high erucic acid rapeseed oil claim 1 , hemp oil claim 1 , safflower oil claim 1 , corn oil claim 1 , olive oil claim 1 , cottonseed oil claim 1 , peanut oil claim 1 , nut oils claim 1 , algal oils claim 1 , fish oils claim 1 , or mixtures thereof.3. The method of claim 2 , wherein the unsaturated fatty acid comprises camelina oil or a mixture of camelina oil and flaxseed oil.4. The method of claim 1 , wherein the acid comprises formic acid or acetic acid claim 1 ,5. The method of claim 1 , wherein the oxidizing agent comprises hydrogen peroxide.6. The method of claim 1 , wherein the partially ...

SPRAY-DRIED BUTYNEDIOL CATALYSTS

A process of forming an ethynylation catalyst includes providing a slurry including water, a copper-containing material, a bismuth-containing material, a structural material, and a binder; spray-drying the slurry to form particles; and calcining the particles to form the ethynylation catalyst. 1. A process of forming an ethynylation catalyst , the process comprising:providing an aqueous slurry comprising water, a copper-containing material, a bismuth-containing material, a structural material, and a binder;spray-drying the slurry to form particles; andcalcining the particles to form the ethynylation catalyst.2. The process of claim 1 , wherein the copper-containing material comprises copper carbonate claim 1 , copper oxalate claim 1 , copper hydroxide claim 1 , cupric oxide claim 1 , or cuprous oxide.3. The process of claim 1 , wherein the bismuth-containing material comprises bismuth carbonate claim 1 , bismuth oxalate claim 1 , bismuth hydroxide claim 1 , bismuth oxide claim 1 , and bismuth acetate.4. The process of claim 1 , wherein the structural material comprises a clay claim 1 , talc claim 1 , calcium silicate claim 1 , kieselguhr claim 1 , alumina claim 1 , carbon claim 1 , or silica.5. The process of claim 1 , wherein the binder comprises a silica sol claim 1 , an alumina sol claim 1 , sodium silicate claim 1 , or aluminum chlorohydrate.6. The process of claim 1 , wherein the particles have an average particle diameter of about 5 μm to about 100 μm.7. The process of claim 1 , wherein the particles have an average particle diameter of about 5 μm to about 60 μm.8. The process of claim 1 , wherein the particles have an average particle diameter of about 15 μm.9. The ethynylation catalyst formed according to .10. A process of activating an ethynylation catalyst claim 1 , the process comprising:{'claim-ref': {'@idref': 'CLM-00009', 'claim 9'}, 'providing the ethynylation catalyst of ;'}exposing the ethynylation catalyst to formaldehyde to form a mixture; ...

FRAGRANCES FROM THE ESTERS OF FATTY ACIDS

The invention relates to the generation of compounds, e.g., fragrance molecules with desirable olfactory properties that can be derived from readily available fatty acids. 2. The compound of claim 1 , wherein Ris H claim 1 , CH claim 1 , or CHCH.3. The compound of claim 1 , wherein Ris —C(O)CH.4. The compound of claim 1 , wherein Ris CHor CHCH.5. The compound of claim 1 , wherein Ris O.8. The method of claim 7 , wherein the methylating agent is methyllithium claim 7 , methylmagnesium chloride claim 7 , or methylmagnesium bromide.9. The method of claim 7 , further comprising the step of performing reductive ozonolysis on the compound of Formula I wherein Ris CHor CHCalkyl to produce a corresponding compound of Formula I wherein Ris O.10. The method of claim 7 , further comprising the step of alkylating the compound of Formula I wherein Ris H with an alkylating agent to form a corresponding compound of Formula I wherein Ris C1-6 alkyl.11. The method of claim 10 , further comprising the step of performing reductive ozonolysis on the compound of Formula I wherein Ris Calkyl and Ris CHor CHCalkyl to produce a corresponding compound of Formula I wherein Ris O.13. The method of claim 12 , wherein the acid is HSOor HCl.14. The method of claim 12 , wherein the alcohol is methanol or ethanol.15. The method of claim 12 , further comprising the step of converting the C(O)OR group of the compound of Formula IV to CHOH claim 12 , and optionally converting the CHOH group to a C(O)H group.16. The method of claim 15 , further comprising the step of converting the compound of Formula IV wherein RO is H to a compound of Formula IV wherein CHC(O)H is CH═CH.17. The compound of claim 1 , wherein Ris H.18. The compound of claim 1 , wherein Ris CH3.19. The compound of claim 1 , wherein Ris CH2.20. The compound of claim 1 , wherein n is 4 or 5. This application claims priority to, and the benefit of, U.S. Ser. No. 62/034,037, filed on Aug. 6, 2014, the contents of which are incorporated ...

NOVEL ETHYNYLATION CATALYST AND METHOD OF MAKING SAME

A novel catalyst useful in the ethynylation of formaldehyde to butynediol is formed by precipitating copper and bismuth from a salt solution of such metals, utilizing an alkali metal hydroxide as the precipitating agent to deposit copper and bismuth hydroxide as a coating around a siliceous carrier particle. 1. A method of preparing a catalyst for the ethynylation of formaldehyde which comprises: depositing by precipitation copper hydroxide via the reaction of an acidic copper salt solution with an alkaline metal hydroxide , on a particulate siliceous carrier , and calcining the treated carrier to yield a copper oxide coating around said particulate siliceous carrier.2. The method of claim 1 , wherein a mixture of copper and bismuth hydroxides are deposited on said carrier.3. (canceled)4. The method of claim 1 , wherein said acidic solution is made of a mixture of copper nitrate and bismuth nitrate.5. The method of claim 1 , wherein said alkali metal hydroxide is sodium hydroxide.6. The method of claim 5 , wherein the sodium hydroxide is provided in a separate vessel from the acidic solution claim 5 , and the siliceous carrier particles are provided in water in a precipitation vessel separate from the sodium hydroxide and acidic solution.7. The method of claim 5 , wherein said acidic solution and said sodium hydroxide are added simultaneously to the precipitation vessel.8. The method of claim 6 , wherein said precipitation is carried out at a constant pH of between about 6 to about 10.9. The method of claim 6 , wherein said precipitation is carried out at a contrast pH of between 7.5 to 9.5.10. The method of claim 6 , wherein said precipitation is carried out at a temperature of about 40° C. to 90° C.11. The method of claim 10 , wherein said temperature is between 45° C. to 65° C.12. The method of claim 1 , wherein said precipitate is filtered claim 1 , washed and dried and the dried material calcined in air at a temperature between about 250 to about 550° C.13. The ...

PERFUME COMPOSITIONS

A perfume composition having controlled release of phytoncides in an atmosphere in order to generate an air condition resembling the air environment of a forest is provided. The perfume composition includes a) at least about 0.6% by weight of at least one phytoncide; and b) a perfume mixture including (i) at least one solvent; and (ii) at least one fragrance ingredient. At least about 25% by weight of the at least one phytoncide is selected from the group consisting of pinene alpha, pinene beta and combinations thereof. 1. A perfume composition having controlled release of phytoncides in an atmosphere in order to generate an air condition resembling the air environment of a forest comprising:a) at least about 0.6% by weight of at least one phytoncide, wherein at least about 25% by weight of the at least one phytoncide is selected from the group consisting of pinene alpha, pinene beta and combinations thereof; andb) a perfume mixture including (i) at least one solvent; and (ii) at least one fragrance ingredient.2. The perfume composition according to claim 1 , wherein the perfume mixture exhibits a Standard Equilibrium Headspace Concentration (HS) distribution curve having greater than about 95 wt % of the perfume mixture exhibiting HSof less than or equal to about 10 claim 1 ,000 μg/L; from about 40 wt % to about 85 wt % of the perfume mixture exhibiting HSof less than or equal to about 1 claim 1 ,000 μg/L; from about 20 wt % to about 75 wt % of the perfume mixture exhibiting HSof less than or equal to about 300 μg/L; and from about 5 wt % to about 50 wt % of the perfume mixture exhibiting a HSof less than or equal to about 100 μg/L.3. The perfume composition according to claim 1 , wherein the composition comprises at least about 1.1% by weight of the at least one phytoncide.4. The perfume composition according to claim 1 , wherein at least 35% of the at least one phytoncide is selected from the group consisting of pinene alpha claim 1 , pinene beta and combinations ...

Process For The Production Of A Fatty Alcohol From A Fatty Acid

In a process for producing fatty alcohol, fatty acid is subjected to esterification with a lower alkanol to form a stream of lower alkyl fatty acid ester(s). The stream is vaporized and then subjected to hydrogenation. The stream is then subjected to transesterification in a wax ester reactor to convert at least a portion of the lower alkyl fatty acid ester(s) to lower alkanol and wax ester(s). The resulting stream is then separated to yield a fatty alcohol(s) steam, a wax ester(s) stream, and an overhead stream comprising fatty alkanol(s) and alkane. The overhead stream is reacted in a wax ester reactor to convert at least a portion of the lower alkyl fatty acid ester to lower alkanol and wax ester(s). The wax ester(s) formed from the alkane is separated, along with any water and/or lower alkanol present. 1. A process for the production of fatty alcohol or alcohols comprising;(a) subjecting a fatty acid or fatty acid mixture to esterification with a lower alkanol in an esterification reactor maintained under esterification conditions to form a stream comprising the corresponding lower alkyl fatty acid ester or esters;(b) vaporising the stream from step (a);(c) subjecting the vaporised stream of step (b) to hydrogenation in a first hydrogenation zone operated under hydrogenation conditions to form a stream comprising fatty alcohol or alcohols and an amount of unconverted lower alkyl fatty acid ester or esters;(d) subjecting the stream from step (c) to transesterification in a wax ester reactor maintained under transesterification conditions in the presence of a transesterification catalyst thereby to convert at least a portion of the lower alkyl fatty acid ester or esters by ester interchange with a corresponding amount of fatty alcohol or alcohols to lower alkanol and to a wax ester or esters;(e) separating the stream from step (d) by distillation to yield a fatty alcohol or alcohols product steam; a wax ester or esters stream; and an overhead stream comprising ...

FLAVOR AND FRAGRANCE FORMULATION (VI)

The present invention relates to the use of specific organic compounds of formula (I) as flavor and fragrance material. Furthermore the invention relates to a new specific organic compound, as well as to flavor and fragrance formulations comprising at least one of the specific organic compounds. 4. Flavor and fragrance formulation according to comprising 0.0001-10 wt-% claim 3 , related to the total weight of the flavor and fragrance formulation claim 3 , of at least one compound of formula (I).5. Flavor and fragrance formulation according to claim 3 , wherein the flavor and fragrance formulation is solid claim 3 , gel-like or liquid.6. Flavor and fragrance formulation according to claim 3 , wherein the flavor and fragrance formulation is a perfume claim 3 , air care product claim 3 , household product claim 3 , laundry product claim 3 , body care product or cosmetic product.9. A process for the manufacture of compound (Ib) comprising the steps ofi) ethinylating 5,6-dimethyl-5-hepten-2-on to 3,6,7-trimethyl-6-octen-1-in-3-ol;ii) acylating 3,6,7-trimethyl-6-octen-1-in-3-ol to 3,6,7-trimethyl-6-octen-1-in-3-yl acetate;iii) hydrogenating the C≡C triple bond 3,6,7-trimethyl-6-octen-1-in-3-yl acetate to the saturated C—C bond in the presence of a Lindlar catalyst leading to the compound of formula (Ib). The present invention relates to the use of specific organic compounds as flavor and fragrance material. Furthermore the invention relates to new specific organic compounds, as well as to flavor and fragrance formulations comprising at least one of the specific organic compounds.In the flavor and fragrance industry there is always a need and demand for compounds that enhance, modify, improve or otherwise positively influence an odor note and therefore give perfumers or other persons the ability to create new fragrances for perfumes, colognes, personal care products, household products or any other products, which comprise flavor and fragrance materials.Surprisingly it was ...

Branched Compounds

A process for producing isomerized olefins, branched aldehydes, branched alcohols and branched surfactants through isomerization, hydroformylation, hydrogenation and surfactant forming reactions. 1. A process , comprising the steps of:providing CO and H2;providing a first catalyst which is an organometallic complex of rhodium and one type of an organophosphorus ligand or an organometallic complex of rhodium and more than one type of an organophosphorus ligand;providing an alpha olefin;isomerizing said alpha olefin by said first catalyst in the presence of CO and H2 at a first pressure to produce an isomerized olefin; andhydroformylating said isomerized olefin by said first catalyst in the presence of CO and H2 at a second pressure different from said first pressure to produce a branched aldehyde; andhydrogenating said branched aldehyde to produce a branched alcohol.2. The process of claim 1 , wherein said isomerizing step produces a reaction product comprising 20 wt. % or greater isomerized olefins.3. The process of claim 1 , wherein said hydroformylating step produces a reaction product comprising 25 wt. % or greater branched aldehydes.4. The process of claim 1 , wherein said hydroformylating step produces a reaction product comprising 50 wt% or greater branched aldehydes.5. The process of claim 1 , wherein said hydrogenation step produces a reaction product comprising 40 wt. % or greater branched alcohols.6. A process claim 1 , comprising the steps of:providing CO and H2;providing a first catalyst which is an organometallic complex of rhodium and one type of an organophosphorus ligand or an organometallic complex of rhodium and more than one type of an organophosphorus ligand;providing an alpha olefin;isomerizing said alpha olefin by said first catalyst in the presence of CO and H2 at a first pressure to produce an isomerized olefin;hydroformylating said isomerized olefin by said first catalyst in the presence of CO and H2 at a second pressure different from said ...

FLAVOR AND FRAGRANCE FORMULATION (I)

The present invention relates to the use of specific organic compounds as flavor and fragrance material. Furthermore the invention relates to new specific organic compounds and their synthesis, as well to flavor and fragrance formulations comprising at least one of the specific organic compounds. 4. Flavor and fragrance formulation according to comprising 0.0001-10 wt-% claim 3 , related to the total weight of the flavor and fragrance formulation claim 3 , of at least one compound of formula (I).5. Flavor and fragrance formulation according to claim 3 , wherein the flavor and fragrance formulation is solid claim 3 , gel-like or liquid.6. Flavor and fragrance formulation according to claim 3 , wherein the flavor and fragrance formulation is a perfume claim 3 , air care product claim 3 , household product claim 3 , laundry product claim 3 , body care product or cosmetic product.10. A process for the manufacture of a compound of formula (II) to (IX) and (XII) as shown in . The present invention relates to the use of specific organic compounds as flavor and fragrance material. Furthermore the invention relates to new specific organic compounds, as well as to flavor and fragrance formulations comprising at least one of the specific organic compounds.In the flavor and fragrance industry there is always a need and demand for compounds that enhance, modify, improve or otherwise positively influence an odor note and therefore give perfumers or other persons the ability to create new fragrances for perfumes, colognes, personal care products, household products or any other products, which comprise flavor and fragrance materials.Surprisingly it was found that the compounds of formula (I) are very useful as flavor and fragrance materials.Therefore the present invention is related to the use of a compound of formula (I)whereinPreferred is the use of at least one compound selected from the group consisting of the compounds of formulae (Ia)-(Ii) and any mixture thereofwherein R, R ...

AVOCADO-DERIVED LIPIDS FOR USE IN TREATING LEUKEMIA

A method of treating a leukemia comprising administering to a subject in need thereof a therapeutically effective amount of a composition comprising a compound of Formula (I) and/or (II) having the structure: OR2 R R1O n OR2 R R1O n I II wherein: 10 ---- represents a single or a double bond; R is OH when C----R is C—R, and R is O when C----R is C═R; n is 1, 3, 5 or 7; and R1 and R2 are independently hydrogen or acetyl, and/or isomers, stereoisomers or solvates thereof and/or mixtures thereof. 2. (canceled)3. The method according to claim 1 , wherein the compound of Formula (I) and/or (II) and/isomers claim 1 , stereoisomers or solvates thereof and/or mixtures thereof inhibits mitochondrial fatty acid oxidation in a leukemia cell or decreases levels of nicotinamide adenine dinucleotide phosphate (NADPH) claim 1 , NADH and/or GSH in a leukemia cell by at least 30% claim 1 , by at least 40% claim 1 , by at least 50% claim 1 , or by at least 60%.4. (canceled)5. The method according to claim 1 , wherein the compound is a compound of Formula (I) and/or a isomers claim 1 , stereoisomers or solvates thereof and/or mixtures thereof.6. The method of claim 5 , wherein the compound is a compound of Formula (I) claim 5 , optionally wherein the compound of Formula (I) has n=5.7. (canceled)8. The method of claim 6 , wherein the compound comprises avocadyne claim 6 , avocadyne acetate and/or avocadynone acetate or a mixture comprising avocadyne claim 6 , avocadyne acetate and/or avocadynone acetate claim 6 , optionally wherein the compound comprises avocadyne claim 6 , optionally avocatin B and/or avocatin A.9. (canceled)10. The method of claim 1 , wherein the method further comprises administering a chemotherapeutic selected from cytarabine and an anthracycline.11. The method claim 1 , wherein the leukemia is an acute myeloid leukemia (AML) claim 1 , an acute lymphoblastic leukemia (ALL) claim 1 , a chronic lymphocytic leukemia (CLL) or a chronic myelogenous leukemia (CML) or the ...

NITROGEN MONOXIDE AS CIS/TRANS ISOMERIZATION CATALYSTS FOR UNSATURATED COMPOUNDS

The present invention relates to a process of a cis/trans isomerization of an unsaturated compound A being selected from the group consisting of unsaturated ketones, unsaturated ketals, unsaturated aldehydes, unsaturated acetals, unsaturated carboxylic acids, esters of an unsaturated carboxylic acid and amides of an unsaturated carboxylic acid using nitrogen monoxide as cis/trans isomerization catalyst. It has been observed that the isomerization is very efficient and fast. 1. A process of a cis/trans isomerization of an unsaturated compound A being selected from the group consisting of unsaturated ketones , unsaturated ketals , unsaturated aldehydes , unsaturated acetals , unsaturated carboxylic acids , esters of an unsaturated carboxylic acid , amides of an unsaturated carboxylic acid and unsaturated alcohols comprising the stepsa) providing a cis or a trans isomer of a unsaturated compound A;b) adding nitrogen monoxide to the cis or trans isomer of the unsaturated compound A of step a);c) heating the mixture of nitrogen monoxide and cis or trans isomer of the unsaturated compound A to a temperature of between 10° C. and the boiling point of the unsaturated compound A, particularly between 20° C. and the boiling point of the unsaturated compound A;leading to a mixture of cis/trans isomers of the unsaturated compound A.2. The process according to wherein the unsaturated compound A is an unsaturated ketone or unsaturated ketal or an unsaturated aldehyde or an unsaturated acetal or an unsaturated alcohol.3. The process according to wherein nitrogen monoxide is introduced to unsaturated compound A at atmospheric pressure or up to 1 MPa over-pressure.4. The process according to wherein the over-pressure amounts to 10 to 300 kPa.5. The process according to wherein nitrogen monoxide is added in step b) as a gas mixture with at least one other gas claim 1 , preferably an inert gas claim 1 , most preferred with nitrogen.6. The process according to claim 5 , wherein the ...

PROCESS FOR THE PRODUCTION OF 2-ALKYL-3-BUTYN-2-OLS

The present invention relates to an improved process for the production of 2-alkyl-3-butin-2-ols; especially to a new purification step. 2. Process according to claim 1 , wherein R is —CH.3. Process according to claim 1 , wherein the extraction solvent is MTBE and/or ETBE claim 1 , preferably MTBE.4. Process according to claim 1 , wherein the alkali metal hydroxide catalyst in step i) is KOH or NaOH claim 1 , preferably KOH.5. Process according to claim 1 , wherein in step iiia) the alkali metal hydroxide is NaOH and/or KOH claim 1 , preferably it is KOH.6. Process according to claim 1 , wherein step iiia) is carried out at temperature of 10-45° C. claim 1 , preferably 20-30° C.7. Process according to claim 1 , wherein the alkali metal hydroxide catalyst in step i) is present in catalytic amounts.8. Process according to claim 1 , wherein alkali metal hydroxide in step iiia) can further be added during step iv).9. Process according to claim 1 , wherein step iiia) is carried out at normal pressure (1 bar). The present invention relates to an improved process for the production of 2-alkyl-3-butin-2-ols; especially to a new purification step.The 2-alkyl-3-butin-2-ols, which are produced by the process according to the present invention are 2-ethyl-3-butin-2-ol (EBI) and 2-methyl-3-butin-2-ol (MBI).EBI and MBI are very well-known and versatile products in the chemical industry. They are used for example in the process of production of isoprenes, vitamin A, vitamin E as well as for the production of fragrance and flavour compounds.Due to the various uses of EBI and MBI, it is important and crucial to have an easy and effective way to produce EBI and MBI in an industrial scale.Usually EBI is produced by the reaction of butan-2-one (methylacetone) and ethyne (acetylene) in the presence of liquid ammonia as a solvent and an alkali metal hydroxide andMBI is produced by the reaction of propan-2-one (acetone) and ethyne (acetylene) in the presence of liquid ammonia as a solvent ...

IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS AND THEIR USE AS FRAGRANCE INGREDIENTS

A compound represented by the formula I 3. A compound according to formula I which is a perfume ingredient.4. The perfume ingredient of which has muguet odour characteristics.5. A perfume composition comprising a compound according to the formula I.6. A perfume composition according to comprising one or more additional fragrance ingredients.7. A perfume composition according to that is free of Lyral™.8. A muguet perfume composition according to .9. A personal care product or household care product or fine fragrance comprising at least a compound of formula 1 of .10. A method of imparting muguet odour characteristics to a personal care product or household care product or fine fragrance claim 1 , said method comprising the step of: including therein a compound according to .11. A perfume composition according to which additionally comprises an anti-oxidant.12. The pro-perfume of which is an aminal and/or enamine of the compound of formula I.13. The pro-perfume of which is a perfume ingredient.14. The pro-perfume of which had muguet odour characteristics.15. A perfume composition comprising a pro-perfume according to .16. A perfume composition according to claim 6 , where the additional fragrance ingredient is (E/Z)-9-hydroxy-5 claim 6 ,9-dimethyldec-4-enal.17. A personal care product or household care product or fine fragrance comprising at least a pro-perfume according to .18. A personal care product or household care product or fine fragrance comprising a perfume composition according to .19. A personal care product or household care product or fine fragrance comprising a perfume composition according to .20. A personal care product or household care product or fine fragrance comprising a perfume composition according to . This invention relates to novel compounds, a method of preparing the compounds, and their use as fragrance ingredients, in particular its use as a fragrance ingredient to impart a muguet (lily of the valley) odour characteristic to a perfume ...

FRAGRANCE COMPOSITIONS COMPRISING COMPOUNDS WITH OLFACTORY QUALITIES

The application relates to compositions comprising compounds of Formula I, Formula II, or Formula III and the use of these compositions in the fragrance industry, i.e., for the production of perfumes, air fresheners, laundry detergents, household cleaning products, liquid or bar soaps, shampoos, conditioners, hair sprays, cosmetics, deodorants, insect repellants, insecticides, and pet litter. 2. The fragrance composition of claim 1 , comprising a compound of Formula I.3. The fragrance composition of claim 1 , wherein Ris H claim 1 , CH claim 1 , or CHCH.4. The fragrance composition of claim 1 , wherein Ris —C(O)CH.5. The fragrance composition of claim 1 , wherein Ris CHor CHCH.6. The fragrance composition of claim 1 , wherein Ris O.7. The fragrance composition of claim 1 , wherein the compound of Formula I or the compound of Formula II or the compound of Formula III imparts a fragrance to the fragrance composition.8. The composition of claim 1 , comprising a compound of Formula II.9. The composition of claim 8 , wherein Rand Rare methyl.10. The composition of claim 8 , wherein n is 4.11. (canceled)12. The composition of claim 1 , comprising a compound of Formula III.13. (canceled)14. (canceled)17. The fragrance composition according to claim 1 , wherein the concentration of the compound of Formula I claim 1 , Formula II claim 1 , or Formula III is 0.0005% to 99.9% by mass claim 1 , 0.0005% to 10% by mass claim 1 , 0.0005% to 1% by mass claim 1 , 0.05% to 50% by mass claim 1 , 0.05% to 10% by mass claim 1 , 0.05% to 1% by mass claim 1 , 0.5% to 10% by mass claim 1 , or 0.5% to 5% by mass.18. (canceled)19. (canceled)20. (canceled)21. (canceled)22. (canceled)23. The fragrance composition of claim 1 , further comprising one or more additives claim 1 , one or more fragrance ingredients claim 1 , or a combination thereof.24. The fragrance composition of claim 1 , wherein the fragrance composition further comprises at least one additive.25. The fragrance composition of ...

ORGANIC COMPOUNDS

The present invention refers to 3,7-dimethyloct-6-en-1-yl methyl carbonate and its use as fragrance ingredient. The invention further refers to fragrance compositions and fragranced articles including it. 1. A method comprising utilizing 3 ,7-dimethyloct-6-en-1-yl methyl carbonate as a fragrance; the method comprising mixing 3 ,7-dimethyloct-6-en-1-yl methyl carbonate alone , as stereoisomeric mixture , or in combination with a base material.2. A fragrance composition comprising:a) 3,7-dimethyloct-6-en-1-yl methyl carbonate; andb) at least one compound selected from 3,7-dimethyloct-7-en-1-yl methyl carbonate, (E)-3,7-dimethylocta-2,6-dien-1-yl methyl carbonate, (Z)-3,7-dimethylocta-2,6-dien-1-yl methyl carbonate and methyl phenethyl carbonate, and mixtures thereof.3. The fragrance composition according to comprising a mixture consisting essentially of 50-95 weight % of 3 claim 2 ,7-dimethyloct-6-en-1-yl methyl carbonate claim 2 , 5-50 weight % of 3 claim 2 ,7-dimethylocta-2 claim 2 ,6-dien-1-yl methyl carbonate claim 2 , up to 20 weight % of 3 claim 2 ,7-dimethyloct-7-en-1-yl methyl carbonate claim 2 , and up to 20 weight % of methyl phenethyl carbonate.4. A fragranced article comprising:a) 3,7-dimethyloct-6-en-1-yl methyl carbonate;b) a consumer product base; and optionallyc) at least one compound selected from 3,7-dimethyloct-7-en-1-yl methyl carbonate, (E)-3,7-dimethylocta-2,6-dien-1-yl methyl carbonate, (Z)-3,7-dimethylocta-2,6-dien-1-yl methyl carbonate and methyl phenethyl carbonate, and mixtures thereof.5. A fragranced article comprising:a) 3,7-dimethyloct-6-en-1-yl methyl carbonate;b) a consumer product base; andc) at least one compound selected from 3,7-dimethyloct-7-en-1-yl methyl carbonate, (E)-3,7-dimethylocta-2,6-dien-1-yl methyl carbonate, (Z)-3,7-dimethylocta-2,6-dien-1-yl methyl carbonate and methyl phenethyl carbonate, and mixtures thereof.6. The fragranced article according to or wherein the consumer product base is selected from fine fragrance ...

1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF

The disclosure relates to the field of specialty chemicals. In particular, the disclosure provides novel 1,3-fatty-diol compounds and derivatives thereof which are useful e.g., in the production of personal care products, surfactants, detergents, polymers, paints, coatings, and as emulsifiers, emollients, and thickeners in cosmetics and foods, as industrial solvents and plasticizers, etc. 112-. (canceled)14. The compound of claim 13 , wherein n is 1 or 5.15. The compound of claim 13 , wherein the double bond is in (Z) configuration.16. The compound of claim 15 , wherein the chiral center at C-3 has an R configuration.17. The compound of claim 13 , wherein the monosaccharide claim 13 , disaccharide claim 13 , trisaccharide claim 13 , or polysaccharide is bound at the anomeric carbon via an α-glycosidic bond.18. The compound of wherein claim 13 , Rand Rare not both H.19. The compound of claim 13 , wherein neither Rnor Rare H.20. The compound of claim 13 , wherein Rand Rare different monosaccharides.21. The compound of claim 13 , wherein Rand Rare the same monosaccharide.22. The compound of claim 13 , wherein the monosaccharide is a pentose sugar or a hexose sugar.23. The compound of claim 22 , wherein the monosaccharide is a hexose sugar selected from the group consisting of allose claim 22 , altrose claim 22 , glucose claim 22 , mannose claim 22 , gulose claim 22 , iodose claim 22 , galactose and talose.24. The compound of claim 23 , wherein the monosaccharide is glucose.25. The compound of claim 13 , wherein Ris glucose.26. The compound of claim 13 , wherein the disaccharide claim 13 , trisaccharide claim 13 , or polysaccharide comprises a pentose sugar claim 13 , a hexose sugar claim 13 , or a mixture thereof.27. The compound of claim 26 , wherein the disaccharide claim 26 , trisaccharide claim 26 , or polysaccharide comprises a hexose sugar selected from the group consisting of allose claim 26 , altrose claim 26 , glucose claim 26 , mannose claim 26 , gulose claim ...

Process for the production of unsaturated alcohols

Disclosed is a process for the conversion of conjugated epoxyalkenes to unsaturated alcohols wherein a conjugated epoxyalkene is catalytically hydrogenated in the presence of a sulfur-modified or sulfided nickel catalyst whereby the epoxide ring is hydrogenolyzed without concomitant hydrogenation of the olefinic unsaturation thereby producing allylic and/or homoallylic alcohols.

Production of butanediol from a methane conversion process

Methods and systems are provided for converting methane in a feed stream to butanediol. The method includes processing acetylene as an intermediate stream to form a hydrocarbon stream including butanediol. A hydrocarbon stream is introduced into a supersonic reactor and pyrolyzed to convert at least a portion of the methane to acetylene. The reactor effluent stream is treated to convert acetylene to another hydrocarbon process. The method according to certain aspects includes controlling the level of carbon monoxide to prevent undesired reactions in downstream processing units.

2단계 방법에 따라 부틴디올을 부탄디올로 촉매 수소화하기 위한 방법

본 발명은 제1단계에서 교반기에서 부유된 팔라듐-캐리어 축매를 이용하고, 제2단계에서 고정층 반응기에서 니켈-캐리어 촉매를 이용하는 2단계 방법으로 이루어진 부틴디올을 부탄디올로 촉매 수소화하기 위한 방법에 관한 것이다. 본 발명에 따르면, a) 제1단계에서 부틴디올에서 부텐디올로의 변환이 완전히 이루어지고, 여기서 부텐디올의 변환율이 50 내지 85%, 바람직하게는 70 내지 80%이며, b) 상기 제1단계에서 이용되는 촉매는 팔라듐-은 -산화 알루미늄-캐리어 촉매이다. 제2단계에서 이용되는 촉매는 소량의 동을 함유하는 니켈-캐리어 촉매이다.

一种钴氧化物掺杂的碱式碳酸铋/氯氧化铋光催化剂及其制备方法

本发明公开了一种钴氧化物掺杂的碱式碳酸铋/氯氧化铋光催化剂，它由碱式碳酸铋和氯氧化铋组成，其重量百分含量为：Bi 2 O 2 CO 3 ，55％～90％；BiOCl 10％～45％，所述钴氧化物掺杂的碱式碳酸铋/氯氧化铋光催化剂为不规则的片形，粒径100‑200nm，钴氧化物掺杂的碱式碳酸铋/氯氧化铋光催化剂形成碱式碳酸铋/氯氧化铋异质结；以上各组分的质量百分含量之和为100％。本发明还公开了钴氧化物掺杂的碱式碳酸铋/氯氧化铋光催化剂的制备方法，本发明方法简单快速，能提高催化剂的催化效率，适合于工业化生产，可广泛用于降解有机污染物、光催化分解水制氢等领域。

Method for preparing 2-butene-1,4-diol

Ethynylation process

Production of alkinols

Process for the isomerization of 2,2,4,4-tetraalkylcyclobutane-1,3-diols

Disclosed is a process for the isomerization of 2,2,4,4-tetraalkylcyclobutane-1,3-diols, such as 2,2,4,4-tetramethylcyclobutane-1,3-diol, by contacting the diol with a supported ruthenium catalyst in the presence of hydrogen at elevated pressures and temperatures. The process is carried under conditions in which there is no net production of 2,2,4,4-tetraalkylcyclobutane-1,3-diol. The process may be carried out in the presence or absence of a solvent and in the liquid or vapor phase.

METHOD OF PRODUCING γ, δ-UNSATURATED ALCOHOL

FIELD: chemical or physical processes. SUBSTANCE: present invention relates to a method of producing γ,δ-unsaturated alcohol of general formula (2): , where R 1 –R 3 each independently represents a hydrogen atom, an alkyl group having 1–10 carbon atoms and optionally substituted with a hydroxy group, an alkenyl group, having 2–10 carbon atoms and optionally substituted with a hydroxy group, or an aryl group having 6–12 carbon atoms and optionally substituted with a hydroxy group, provided that R 1 and R 3 can bond with each other to form a ring. Method involves reaction of α-olefin, represented by following general formula (1) , where R 1 –R 3 are as defined above, with an aqueous solution of formaldehyde in the presence of alcohol having 3–10 carbon atoms, wherein formaldehyde aqueous solution is subjected to preliminary heating at 30–220 °C before the stage. EFFECT: disclosed method enables to obtain an end product with high output and good output. 9 cl, 1 tbl, 15 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 742 304 C1 (51) МПК C07C 29/38 (2006.01) C07C 33/025 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК C07C 29/38 (2020.08) (21)(22) Заявка: 2019123426, 26.01.2018 (24) Дата начала отсчета срока действия патента: (73) Патентообладатель(и): КУРАРЕЙ КО., ЛТД. (JP) Дата регистрации: 04.02.2021 31.01.2017 JP 2017-015826 (45) Опубликовано: 04.02.2021 Бюл. № 4 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 02.09.2019 (86) Заявка PCT: 2 7 4 2 3 0 4 R U (87) Публикация заявки PCT: WO 2018/143104 (09.08.2018) C 1 C 1 JP 2018/002577 (26.01.2018) 2 7 4 2 3 0 4 (56) Список документов, цитированных в отчете о поиске: WO 2015186699 A1, 10.12.2015. JP 7285899 A, 31.10.1995. CN 102206136 A, 05.10.2011. DE 1275049 B, 14.08.1968. SU 249371 A1, 28.10.1971. Приоритет(ы): (30) Конвенционный приоритет: R U 26.01.2018 (72) Автор(ы): СУДЗУКИ, Ютака (JP), СИМИДЗУ, Масаки (JP) Адрес для переписки: 129090, Москва, ...

γ, δ-unsaturated alcohol manufacturing method

一种γ，δ‑不饱和醇的制造方法，其是使下述通式(1)：(R 1 ～R 3 各自独立地表示氢原子、任选被羟基取代的碳数1～10的烷基、任选被羟基取代的碳数2～10的烯基、或者任选被羟基取代的碳数6～12的芳基。其中，R 1 与R 3 任选彼此连接而形成环)所示的α‑烯烃与甲醛在加热条件下反应从而制造下述通式(2)(R 1 ～R 3 如上述定义)所示的γ，δ‑不饱和醇的方法，上述方法具有使上述α‑烯烃与甲醛水溶液在碳数3～10的醇的存在下接触的工序，在该工序之前将该甲醛水溶液以30～220℃进行预加热。

一种异戊烯醇的制备方法

本发明公开一种异戊烯醇的制备方法，该制备方法是在氢气气氛中，以5％的Pd/C作为主催化剂，在助催化剂存在的条件下，将原料3‑甲基‑3‑丁烯‑1‑醇异构转化成异戊烯醇；具体的，通过合成反应釜，将按照重量比均匀混合的主催化剂与助催化剂与反应原料混合均匀后，在50℃～110℃温度下恒温加热反应60‑100min后结束反应。本发明所述异戊烯醇的制备方法能够很好的抑制过氢产物异戊醇的产生，过氢产物异戊醇的产率能够抑制在7％以下，并且在较高温度下也有很好的效果，温度的提高，也改变了平衡，从而使得目标产物的含量增高，且原料的一次性转化率得到了有效提升。

Process

Spray-dried butynediol catalyst

Perfume compositions containing 4,8-dimethyl-3,7-nonadien-2-one

Parfümkompositionen, die 4,8-Dimethyl-3,7-nonadien-2-on enthalten, können in der Feinparfümerie und zur Parfümierung industrieller Produkte verwendet werden. Perfume compositions containing 4,8-dimethyl-3,7-nonadien-2-one can be found in the Fine perfumery and used to perfume industrial products.

Improved process for hydrogenation of maleic acid to 1,4-butanediol

Wheat midge sex pheromone precursor and wheat midge sex pheromone

本发明涉及一种麦红吸浆虫性信息素前体化合物，以及一种麦红吸浆虫性信息素的合成方法与应用。麦红吸浆虫性信息素前体化合物的合成方法：氮气保护下，在配有磁力搅拌器的史莱克管中，加入CuCl和盐酸羟胺，冰浴冷却，再注入质量分数为70%的正丁胺水溶液，加入手性炔醇II，然后缓慢加入溴代手性炔醇III，反应液在低温反应，反应结束后，用乙醚萃取，用饱和氯化钠水溶液洗涤，干燥，减压得粗产物，经柱层析纯化，得到手性醇IV。本发明制备的小麦吸浆虫性信息素具有高光学活性；此外本发明所述的合成路线简单，成本低廉，具有商业应用价值。

Process for augmenting or enhancing the fresh air aroma of clothing

Described is a process for imparting an "air dried cloth" aroma to cloth, synthetic or natural, previously dried using a clothes drier, comprising the step of contacting the cloth prior to drying with an aroma augmenting or enhancing quantity of either (i) a mixture consisting essentially of: (a) from about 0.5 up to about 5% by weight of said composition of n-hexanal; (b) from about 2 up to about 12% by weight of said composition of n-heptanal; (c) from about 5 up to about 15% by weight of said composition of n-octanal; (d) from about 40 up to about 70% by weight of said composition of n-nonanal; (e) from about 10 up to about 30% by weight of said composition of n-decanal; (f) from about 0.5 up to about 5% by weight of said composition of n-undecanal; (g) from about 0.5 up to about 5% by weight of said composition of n-dodecanal; (h) from about 0.5 up to about 5% by weight of said composition of n-tridecanal; (i) from about 0 up to about 5% by weight of said composition of n-tetradecanal; (j) from about 0 up to about 5% by weight of said composition of n-pentadecanal; or (ii) first contacting the cloth with at least one organic acid selected from the group consisting of oleic acid, linoleic acid, and linolenic acid or a glyceride ester thereof, then exposing the resultant treated cloth to air and light in the ultra violet wavelengths prior to drying. Also described is a process for augmenting or enhancing the aroma of consumable materials selected from the group consisting of perfume compositions, colognes and perfumed articles (e.g. perfumed polymers, solid or liquid anionic, cationic, nonionic or zwitterionic detergents, fabric softener compositions, fabric softener articles and hair preparations) by intimately admixing with the perfume composition, cologne or perfumed article composition or component, an aroma augmenting or enhancing quantity of a mixture consisting essentially of: (a) from about 0.5 up to about 5% by weight of said composition of n- ...

Process for augmenting or enhancing the fresh air aroma of consumable materials with a mixture of n-alkanals having from 6 to 15 carbon atoms

Described is a process for imparting an "air dried cloth" aroma to cloth, synthetic or natural, previously dried using a clothes drier, comprising the step of contacting the cloth prior to drying with an aroma augmenting or enhancing quantity of either (i) a mixture consisting essentially of: (a) from about 0.5 up to about 5% by weight of said composition of n-hexanal; (b) from about 2 up to about 12% by weight of said composition of n-heptanal; (c) from about 5 up to about 15% by weight of said composition of n-octanal; (d) from about 40 up to about 70% by weight of said composition of n-nonanal; (e) from about 10 up to about 30% by weight of said composition of n-decanal; (f) from about 0.5 up to about 5% by weight of said composition of n-undecanal; (g) from about 0.5 up to about 5% by weight of said composition of n-dodecanal; (h) from about 0.5 up to about 5% by weight of said composition of n-tridecanal; (i) from about 0 up to about 5% by weight of said composition of n-tetradecanal; (j) from about 0 up to about 5% by weight of said composition of n-pentadecanal; or (ii) first contacting the cloth with at least one organic acid selected from the group consisting of oleic acid, linoleic acid, and linolenic acid or a glyceride ester thereof, then exposing the resultant treated cloth to air and light in the ultra violet wavelengths prior to drying. Also described is a process for augmenting or enhancing the aroma of consumable materials selected from the group consisting of perfume compositions, colognes and perfumed articles (e.g. perfumed polymers, solid or liquid anionic, cationic, nonionic or zwitterionic detergents, fabric softener compositions, fabric softener articles and hair preparations) by intimately admixing with the perfume composition, cologne or perfumed article composition or component, an aroma augmenting or enhancing quantity of a mixture consisting essentially of: (a) from about 0.5 up to about 5% by weight of said composition of n- ...

Process for augmenting or enhancing the fresh air aroma of consumable materials and clothing and composition useful for same

Described is a process for imparting an "air dried cloth" aroma to cloth, synthetic or natural, previously dried using a clothes drier, comprising the step of contacting the cloth prior to drying with an aroma augmenting or enhancing quantity of either (i) a mixture consisting essentially of: (a) from about 0.5 up to about 5% by weight of said composition of n-hexanal; (b) from about 2 up to about 12% by weight of said composition of n-heptanal; (c) from about 5 up to about 15% by weight of said composition of n-octanal; (d) from about 40 up to about 70% by weight of said composition of n-nonanal; (e) from about 10 up to about 30% by weight of said composition of n-decanal; (f) from about 0.5 up to about 5% by weight of said composition of n-undecanal; (g) from about 0.5 up to about 5% by weight of said composition of n-dodecanal; (h) from about 0.5 up to about 5% by weight of said composition of n-tridecanal; (i) from about 0 up to about 5% by weight of said composition of n-tetradecanal; (j) from about 0 up to about 5% by weight of said composition of n-pentadecanal; or (ii) first contacting the cloth with at least one organic acid selected from the group consisting of oleic acid, linoleic acid, and linolenic acid or a glyceride ester thereof, then exposing the resultant treated cloth to air and light in the ultra violet wavelengths prior to drying.

A kind of bulky grain copper bismuth catalyst and its preparation method and application

本发明公开一种大颗粒铜铋催化剂的制备方法，包括以下步骤：（1）配制含有铜盐和铋盐的酸性溶液；（2）配制沉淀剂溶液；（3）往反应釜中加入底水，升温加热至反应温度；（4）采取并流的方式，将步骤（1）的酸性溶液和步骤（2）的沉淀剂溶液滴加到反应釜中；（5）当剩余酸性溶液为步骤（1）配制酸性溶液总量的4/5~9/10时，停止反应，进行老化；（6）老化结束后，继续进行反应并从反应釜底部继续通入气体CO 2 ；（7）当剩余酸性溶液为步骤（1）配制酸性溶液总量的1/5‑1/10时，提高向反应体系加水的流量；（8）待反应结束后，进行老化，老化结束后，洗涤，过滤。该方法制备的催化剂具有耐磨性好，催化剂颗粒大小均匀适中、活性稳定性高，丙炔醇的产量高等优点。

Process for producing DL-tocopherols and intermediates therefor

本发明涉及制备d1-生育酚的方法和用于该制备方法的中间体。用本发明获得的d1-生育酚为可用作食品添加剂、饲料和药物的有用的化合物。

Method for preparing 3-methyl-2-butenol through photocatalysis

本发明公开了一种光催化制备3‑甲基‑2‑丁烯醇的方法，通过光催化反应高效地使3‑甲基‑3‑丁烯醇发生异构化反应得到3‑甲基‑2‑丁烯醇。该方法解决了3‑甲基‑2‑丁烯醇传统的制备过程中产生异戊醇的问题，具有反应条件温和、操作简单、产品收率高、分离容易的优点。

METHOD OF ETHILATION

ÐÎÑÑÈÉÑÊÀß ÔÅÄÅÐÀÖÈß (19) RU (11) 2005 107 412 (13) A (51) ÌÏÊ C07C 29/42 (2006.01) ÔÅÄÅÐÀËÜÍÀß ÑËÓÆÁÀ ÏÎ ÈÍÒÅËËÅÊÒÓÀËÜÍÎÉ ÑÎÁÑÒÂÅÍÍÎÑÒÈ, ÏÀÒÅÍÒÀÌ È ÒÎÂÀÐÍÛÌ ÇÍÀÊÀÌ (12) ÇÀßÂÊÀ ÍÀ ÈÇÎÁÐÅÒÅÍÈÅ (21), (22) Çà âêà: 2005107412/04, 09.08.2003 (71) Çà âèòåëü(è): ÄÑÌ ÈÏ ÀÑÑÅÒÑ Á.Â. (NL) (30) Ïðèîðèòåò: 16.08.2002 EP 02018458.6 (43) Äàòà ïóáëèêàöèè çà âêè: 27.01.2006 Áþë. ¹ 03 (86) Çà âêà PCT: EP 03/08867 (09.08.2003) (87) Ïóáëèêàöè PCT: WO 2004/018400 (04.03.2004) Àäðåñ äë ïåðåïèñêè: 101000, Ìîñêâà, Ì.Çëàòîóñòèíñêèé ïåð., 10, êâ.15, "ÅÂÐÎÌÀÐÊÏÀÒ", È.À.Âåñåëèöêîé R U Ôîðìóëà èçîáðåòåíè 1. Ñïîñîá ïîëó÷åíè àöåòèëåíîâîíåíàñûùåííîãî ñïèðòà ðåàêöèåé êàðáîíèëüíîãî ñîåäèíåíè ñ àöåòèëåíîì â ïðèñóòñòâèè àììèàêà è ãèäðîêñèäà ùåëî÷íîãî ìåòàëëà, îòëè÷àþùèéñ òåì, ÷òî êàðáîíèëüíîå ñîåäèíåíèå ïðåäñòàâë åò ñîáîé ìåòèëýòèëêåòîí, ìåòèëãëèîêñàëüäèìåòèëàöåòàëü, 6-ìåòèë-5-ãåïòåí-2-îí, 6-ìåòèë-5-îêòåí-2-îí, ãåêñàãèäðîïñåâäîèîíîí, 4-(2,6,6-òðèìåòèë-1-öèêëîãåêñåí-1-èë)-3-áóòåí-2-îí èëè 6,10,14òðèìåòèë-2-ïåíòàäåêàíîí, ãèäðîêñèä ùåëî÷íîãî ìåòàëëà èñïîëüçóþò â âîäíîì ðàñòâîðå è ìîë ðíîå ñîîòíîøåíèå ìåæäó ýòèì ãèäðîêñèäîì ùåëî÷íîãî ìåòàëëà è êàðáîíèëüíûì ñîåäèíåíèå ñîñòàâë åò ìåíüøå 1:200. 2. Ñïîñîá ïî ï.1, â êîòîðîì ìîë ðíîå ñîîòíîøåíèå ìåæäó ãèäðîêñèäîì ùåëî÷íîãî ìåòàëëà è êàðáîíèëüíûì ñîåäèíåíèåì ñîñòàâë åò îò ïðèìåðíî 1:500 äî 1:200. 3. Ñïîñîá ïî ï.1, â êîòîðîì ìîë ðíîå ñîîòíîøåíèå ìåæäó ãèäðîêñèäîì ùåëî÷íîãî ìåòàëëà è êàðáîíèëüíûì ñîåäèíåíèåì ñîñòàâë åò îò ïðèìåðíî 1:300 äî ïðèìåðíî 1:220. 4. Ñïîñîá ïî ï.1, â êîòîðîì êàðáîíèëüíîå ñîåäèíåíèå ïðåäñòàâë åò ñîáîé 6-ìåòèë-5ãåïòåí-2-îí, à ïðîäóêòîì âë åòñ äåãèäðîëèíàëîîë. 5. Ñïîñîá ïî ï.1, â êîòîðîì ãèäðîêñèä ùåëî÷íîãî ìåòàëëà ïðåäñòàâë åò ñîáîé ãèäðîêñèä êàëè . 6. Ñïîñîá ïî ï.1, â êîòîðîì ðåàêöèþ ïðîâîä ò ïðè òåìïåðàòóðå îò ïðèìåðíî 0 äî ïðèìåðíî 40°Ñ, à äàâëåíèå äë óäåðæàíè àììèàêà â ñæèæåííîì ñîñòî íèè ðàâíî ñîîòâåòñòâóþùåìó çíà÷åíèþ, çàâèñ ùåìó îò ðåàêöèîííîé òåìïåðàòóðû, îò ïðèìåðíî 5 äî ïðèìåðíî 20 áàð (îò ïðèìåðíî 0,5 äî ïðèìåðíî 2 ÌÏà). 7. ...

A kind of conjugation diine glycol compound and application thereof

本发明属于药物化学技术领域，具体涉及一种共轭二炔二醇类化合物及其用途。本发明的目的在于提供对神经细胞具有保护作用的共轭二炔二醇类化合物，该类化合物对皮质酮损伤的PC12细胞起到保护作用。本发明共轭二炔二醇类化合物，具有如下的结构通式： 其中R 1 代表‑(CH 2 )n‑，n＝2‑8；‑CH＝CH‑(CH 2 )m‑，m＝1‑8；‑苯基(CH 2 )o‑(邻，间，对)，o＝1‑8。

A Method for Preparation of Allyl Alcohol

More particularly, the present invention relates to a process for producing allyl alcohol, which comprises reacting glycerol and formic acid under specific synthesis conditions to remarkably increase the content of allyl alcohol in the liquid reaction product, And to a new method for producing allyl alcohol capable of minimizing formic acid.

Method for preparing alkyne diols possibly comprising alkyne monoalcohols

FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to method for preparing alkyne diols possibly comprising alkyne mono- alcohols. Method involves interaction of ketones with acetylene hydrocarbons on organic solvent medium in the presence of a base followed by hydrolysis and isolation of the end substance. Acetylene hydrocarbons are taken among acetylene and alkyne aminoalcohols. Potassium alcoholates of primary and/or secondary alcohols or potassium alcoholates of primary and/or secondary alcohols containing KOH are used as a base. In using acetylene as an acetylene hydrocarbon the ratio of used ketone to acetylene is from 1.9:1 to 2.1:1 and the ratio of potassium alcoholate to used ketone is from 0.9:1 to 2.1: 1; in using alkyne monoalcohols as acetylene hydrocarbons the ratio of used alkyne monoalcohol to used ketone is from 1:0.8 to 1:1.2 and the ratio of potassium alcoholate to used ketone is from 1.5:1 to 2.2:1 to yield precipitating gel-like adducts of alkyne diols and, possibly, alkyne monoalcohol and a base. As result, the reaction mass retains capacity for stirring for all reaction time followed by hydrolysis of components. Method provides reducing amount of used solvent and provides preparing substances with improved indices for the further using. EFFECT: simplified and improved preparing method. 8 cl, 10 ex зЗэ9Эдгссс ПЧ сэ содержащих ацетиленовыми органическом растворителе в присутствии основания с последующим гидролизом и ацетиленового (19) РОССИЙСКОЕ АГЕНТСТВО ПО ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ ВИ "” 2 221 768. (51) МПК? 13) С2 С 07С 33/044, 29/42 12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ РОССИЙСКОЙ ФЕДЕРАЦИИ (21), (22) Заявка: 2001107596/04, 13.08.1999 (24) Дата начала действия патента: 13.08.1999 (30) Приоритет: 17.08.1998 ОЕ 19837211.6 (46) Дата публикации: 20.01.2004 (56) Ссылки: СВ 1354011 А, 22.05.1974. СВ 1329815 А, 12.09.1973. СВ 1264194 А, 16.02.1972. ЗИ 318293 А, 30.08.1979. ЗЦ 639849 А, 30.12.1978. Щелкунов А.В. и др. ...

A kind of reactor and reaction system of synthesizing methyl butynol

本发明公开了一种合成甲基丁炔醇的反应器和反应系统，所述反应器包括依次连接的一段管式反应器和二段管式反应器，其中，所述一段管式反应器和二段管式反应器均包括管式反应器和设置在所述管式反应器内部的静态混合器。所述反应系统包括通过管路顺次连接的搅拌反应釜、反应器和终止混合器，其中，所述反应器采用上述合成甲基丁炔醇的反应器，所述搅拌反应釜的出料口与一段管式反应器的进料口连接并且所述二段管式反应器的出料口与终止混合器的进料口连接。本发明的合成甲基丁炔醇的反应器和反应系统不仅大大缩短了反应器的管程长度，而且也实现了物料的有效混合，避免了副反应的发生，与早期工艺相比大幅度提高了产品的收率。

Method of synthesizing isopentenol from butenol

本发明适用于异戊烯醇的合成方法技术领域，提供了一种由丁烯醇合成异戊烯醇的方法，在由固体超强碱和异丙醇铝组成的催化剂的催化作用下，使3-甲基-3-丁烯醇的双键异构化生成异戊烯醇的方法，其中固体超强碱为Na-Na 2 CO 3 /γ-Al 2 O 3 ，所述催化剂的用量为3-甲基-3-丁烯醇质量的0.2％～12％，催化剂中固体超强碱与异丙醇铝的质量比为1:1～1:2；反应的压强为0.5～4MPa，温度为100℃～140℃，时间为2～3h。本发明的反应条件温和，催化剂活性高、易于分离且可重复使用，生产成本低，环境友好，生产安全，产品纯度和选择性高，绿色环保，大大降低了成本，是一种高效经济的合成方法，前景广阔。

Fragrance composition

2-butene-1,4-diol production process

FIELD: industrial organic synthesis. SUBSTANCE: process consists in hydrogenation of butinediol on catalyst containing palladium and zinc and is distinguished by conducting process on catalyst additionally containing copper and/or silver. EFFECT: increased activity and selectivity of catalyst and avoided use of toxic substances when preparing and exploiting catalysts. 10 cl, 1 tbl, 7 ex ДСЗУЗЯТсС ПЧ сэ (19) РОССИЙСКОЕ АГЕНТСТВО ПО ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ ВИ” 2154 527‘ (51) МПК? 13) С2 В 01 4 23/60, С 07 С 29/17, 33/035/(В 01 3 23/60, 103:12, 103:14) 12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ РОССИЙСКОЙ ФЕДЕРАЦИИ (21), (22) Заявка: 97101900/04, 04.07.1995 (24) Дата начала действия патента: 04.07.1995 (30) Приоритет: 06.07.1994 ОЕ Р 4423738.3 (46) Дата публикации: 20.08.2000 (56) Ссылки: ОЕ 2431929 В.2, 01.07.1976. ОЕ 2460078 АЛ, 03.07.1975. 5Ц 470304 А, 08.08.1975. 5Ц 311887 А, 19.10.1971. ЕР 0312233 А, 19.04.1989. (85) Дата перевода заявки РСТ на национальную фазу: 06.02.1997 (86) Заявка РСТ: ЕР 95/02592 (04.07.1995) (87) Публикация РСТ: М/О 96/01242 (18.01.1996) (98) Адрес для переписки: 103064, Москва, ул. Казакова 16, НИИР-Канцелярия "Патентные поверенные Квашнин, Сапельников и Партнеры", Квашнину В.П. (71) Заявитель: БАСФ АГ (О0Е) (72) Изобретатель: Маттиас ИРГАНГ (0Е), Фолькмар МЕНГЕР (0Е), Эрнест МИЗЕН (ОЕ), Петер ШТОПС (ОЕ), Фритц ГРАФ (0Е) (73) Патентообладатель: БАСФ АГ (0Е) (54) СПОСОБ ПОЛУЧЕНИЯ БУТЕН-2-ДИОЛА-1,4 (57) Описывается способе получения бутен-2-диола-1,4, который находит применение для получения некоторых важных средств защиты растений, фармацевтических средств и промежуточных продуктов. Способ осуществляют путем гидрирования бутиндиола на катализаторе, содержащем палладий и цинк Процесс ведут на катализаторе, содержащем дополнительно медь или серебро, или их смесь. Технический результат - увеличение активности и избирательности катализатора и одновременно избежание использования токсических веществ при получении и применении катализаторов. 9 з.п. ф- ...

Process And Catalyst For The Selective Hydrogenation Of Vutine Diol To Butene Diol

구리 및 아연 또는 은 및 아연이 도핑제로서 첨가된 팔라듐 촉매를 사용하는 부틴-2-디올(1,4)의 부텐-2-디올(1,4)로의 선택적 수소화 방법을 기재한다. 바람직한 양태에서, 촉매의 조성을 최적화시킴으로써, 또한 촉매 제조 공정 동안에 독성 물질을 취급할 필요를 배제시키면서, 문제의 촉매의 활성 및 선택성을 증진시킬 수 있었다. 2-diol (1,4) with butene-2-diol (1,4) using copper and zinc or a palladium catalyst to which silver and zinc are added as a dopant. In a preferred embodiment, by optimizing the composition of the catalyst, the activity and selectivity of the catalyst in question could be enhanced, while eliminating the need to treat the toxic material during the catalyst preparation process.

1,3-fatty diol compounds and derivatives thereof

본 개시내용은 특수 화학 물질의 분야에 관한 것이다. 특히, 본 개시내용은, 예를 들어, 개인 위생 용품, 계면 활성제, 세제, 중합체, 페인트, 코팅의 제조에 유용하고, 화장품 및 식품의 유화제, 연화제, 및 증점제로서, 산업용 용매 및 가소제 등으로서 유용한, 식 (II)와 (IV)의 신규한 1,3-지방-디올 화합물과 그 유도체, 특히, 그 지코시드(gycosides)를 제공한다. (II) (IV) The present disclosure relates to the field of specialty chemicals. In particular, the present disclosure is useful, for example, in the manufacture of personal care products, surfactants, detergents, polymers, paints, coatings, as emulsifiers, emollients, and thickeners in cosmetics and foods, as industrial solvents and plasticizers, etc. , provide novel 1,3-fatty-diol compounds of formulas (II) and (IV) and derivatives thereof, in particular gycosides thereof. (II) (IV)

Composition comprising novel acetylenic alcohol compound or the extract of reniochalina sp. for preventing and treating cancer

본 발명은 신규 아세틸렌 알코올계 화합물 또는 열대 해면동물 레니오카리나 추출물을 유효성분으로 함유하는 암 질환의 예방 및 치료를 위한 조성물에 관한 것으로, 상세하게는 본 발명의 신규 화합물 또는 레니오카리나 추출물은 다양한 암세포주에 대해 성장 억제 활성 효과를 나타냄을 확인함으로써, 암 질환의 예방 및 치료에 유용한 약학 조성물로 이용될 수 있다.

Method for preparing γ, δ-unsaturated alcohol

하기 일반식 (1) : (R 1 ∼ R 3 은 각각 독립적으로 수소 원자, 하이드록실기로 치환되어 있어도 되는 탄소수 1 ∼ 10 의 알킬기, 하이드록실기로 치환되어 있어도 되는 탄소수 2 ∼ 10 의 알케닐기, 또는 하이드록실기로 치환되어 있어도 되는 탄소수 6 ∼ 12 의 아릴기를 나타낸다. 단, R 1 과 R 3 은 서로 연결되어 고리를 형성하고 있어도 된다.) 로 나타내는 α-올레핀과 포름알데하이드를 가열 조건 하에서 반응시키고, 하기 일반식 (2) : (R 1 ∼ R 3 은 상기 정의와 같다.) 로 나타내는 γ,δ-불포화 알코올을 제조하는 방법으로서, 상기 방법은 상기 α-올레핀과 포름알데하이드 수용액을 탄소수 3 ∼ 10 의 알코올의 존재하에서 접촉시키는 공정을 갖고, 그 공정 전에 그 포름알데하이드 수용액을 30 ∼ 220 ℃ 에서 예비 가열하는, γ,δ-불포화 알코올의 제조 방법이다.

A kind of preparation method of bismuth ferrate nano hollow ball

本发明公开了一种铁酸铋纳米空心球的制备方法，包括以下步骤：室温下将十二烷基苯磺酸钠和苯乙烯加入到装有去离子水的加热容器中，搅拌下加入过硫酸钾恒温反应2h；加入苯乙烯、丙烯酸、过硫酸钾和碳酸氢钠，反应2～5h后离心，得到聚(苯乙烯‑丙烯酸)纳米球；超声分散使聚(苯乙烯‑丙烯酸)纳米球完全分散在水中，加入聚乙烯吡咯烷酮，同时加入摩尔比为1:1的九水硝酸铁和五水硝酸铋，超声分散成悬浊液；加入尿素水溶液，恒温反应后抽滤得到聚(苯乙烯‑丙烯酸)铁酸铋复合纳米球，高温煅烧后得到铁酸铋纳米空心球。本发明所制备的铁酸铋纳米空心球，尺寸均匀，分散性较好，无团聚，比表面积较大，对可见光吸收效果比较明显，是一种新型的光催化和光伏新材料。

Method for Preparing Acetylenic Alcohols by Continuous Process

본 발명은 불균일계 강염기성 음이온 교환수지를 사용한 에티닐화 반응 (Ethynylation)을 통해 아세틸렌 알코올 화합물을 연속적으로 제조하는 방법에 관한 것으로, 좀 더 상세하게는 기체 상태의 아세틸렌, 하기 화학식 2로 표시되는 -CH 2 -CO-CH 2 -기를 포함하는 케톤 및 비양자성 용매를 혼합하여, 강염기성인 4차 수산화암모늄 음이온 교환수지가 충진된 반응기에 공급하여 -20∼20℃의 온도범위 및 1∼10㎏/㎠의 압력범위 하에서 반응시키며, 여기서 상기 케톤과 아세틸렌의 반응몰비는 1.0 : 2.0∼15.0이고, 케톤과 용매의 반응 부피비는 1.0 : 2.0∼6.0 범위이며, LHSV는 0.1∼5.0 범위인 아세틸렌 알코올 화합물의 연속 제조방법에 관한 것이다. 본 발명은 케톤들의 전환율이 95%이상을 유지하며 아세틸렌 알코올의 선택도를 97%이상으로 유지할 수 있다. The present invention relates to a method for continuously preparing an acetylene alcohol compound through an ethynylation reaction using heterogeneous strong base anion exchange resin, more specifically, a gaseous acetylene, represented by the following formula (2): Ketones containing a CH 2 -CO-CH 2 -group and aprotic solvents were mixed, and fed to a reactor filled with a strong basic quaternary ammonium hydroxide anion exchange resin, and a temperature range of -20 to 20 ° C and 1 to 10 kg / The reaction molar ratio of ketone and acetylene is 1.0: 2.0-15.0, the reaction volume ratio of ketone and solvent is 1.0: 2.0-6.0, and LHSV is 0.1-5.0. It relates to a continuous manufacturing method. The present invention can maintain the conversion of ketones of 95% or more and maintain the selectivity of acetylene alcohol of 97% or more. 아세틸렌, 케톤, 음이온 교환수지, 비양성자성 용매, 아세틸렌 알코올 Acetylene, ketone, anion exchange resin, aprotic solvent, acetylene alcohol

Aromatic composition with jasmine zambak aroma

FIELD: food industry. SUBSTANCE: aromatic composition includes a base composition and an additional ingredient. The base composition contains benzyl acetate and cis-jasmone. The additional ingredient is chosen from 2.6-dimethyl-1.7-octadiene-3.6-diol and dehydrolinalool. Preferably, the aromatic composition additionally includes 3.7-dimethyl-1.5-octadiene-3.7-diol. Preferably, the total quantity of aromatic ingredients is equal to 0.01 - 20 % of the aromatic composition total weight. EFFECT: invention allows to produce an aromatic composition with a soft, fresh and natural aroma of flowering jasmine. 4 cl, 6 tbl, 2 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2 472 850 (13) C2 (51) МПК C11B 9/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21)(22) Заявка: 2010110471/13, 01.09.2008 (24) Дата начала отсчета срока действия патента: 01.09.2008 (73) Патентообладатель(и): ШИСЕЙДО КОМПАНИ ЛТД. (JP) (43) Дата публикации заявки: 10.10.2011 Бюл. № 28 2 4 7 2 8 5 0 (45) Опубликовано: 20.01.2013 Бюл. № 2 2 4 7 2 8 5 0 R U (85) Дата начала рассмотрения заявки PCT на национальной фазе: 05.04.2010 C 2 C 2 (56) Список документов, цитированных в отчете о поиске: ITO, Y et al."Identification of Potent Odorants in Chinese Jasmine Green Tea Scented with Flowers of Jasminum sambac", Journal of Agricultural and Food Chemistry, 2002, Vol.50, N17, p.4878-4884. JP 2002275494 A, 25.09.2002. JP 58-140009 A, 19.08.1983. (86) Заявка PCT: JP 2008/065696 (01.09.2008) (87) Публикация заявки РСТ: WO 2009/031505 (12.03.2009) Адрес для переписки: 191186, Санкт-Петербург, а/я 230, "АРСПАТЕНТ", пат. пов. В.В.Дощечкиной (54) АРОМАТИЧЕСКАЯ КОМПОЗИЦИЯ С АРОМАТОМ ЖАСМИНА САМБАК (57) Реферат: Изобретение относится к ароматической композиции, обладающей натуральным ароматом жасмина самбак. Ароматическая композиция включает основную композицию и дополнительный ингредиент. Основная композиция содержит бензилацетат и цисжасмон. Дополнительный ингредиент выбирают из ...

How to separate the mixed components from the butynediol solution

본 발명은 아세틸렌, 포름알데히드, 프로파길 알코올이나 이와 비슷한 용액, 부틴디올-합성물에서 증류된 생-부틴디올액과 같이 혼합 성분들을 분리하는 방법이며, 여기에서 혼합 성분들은 과열 증기 스트립핑으로 생-부틴디올액에서 분리된다. 이때 과열 증기 시트립핑에 운반된 수증기는 105℃내지 140℃범위의 온도와 1.2bar 내지 1.5bar 범위의 압력을 나타낸다.

Specific α, the method for β unsaturated aldehydes are produced by rearrangement process

本发明涉及改进的生产特定α，β‑不饱和醛的方法。

Monomer for preparing cement admixture and method for preparing the same

본 발명은 시멘트 혼화제 제조용 모노머 및 이의 제조 방법에 관한 것이다. 상기 시멘트 혼화제 제조용 모노머는 디카르복실산에서 유래한 말단부를 포함하는 것을 특징으로 한다. 본 발명에 따른 모노머로 제조한 시멘트 혼화제는 분산성과 작업성 유지 성능이 모두 우수한 모르타르를 형성할 수 있다. The present invention relates to a monomer for producing a cement admixture and a method for producing the same. The monomer for preparing a cement admixture is characterized by containing a terminal portion derived from a dicarboxylic acid. The cement admixture prepared from the monomer according to the present invention can form a mortar having both excellent dispersibility and workability.

Prepration method of cross-linking compound

본 발명은 고흡수성 수지의 제조를 위해 사용 가능한 가교제 화합물을 간단한 방법으로, 보다 높은 수율로 얻을 수 있는 가교제 화합물의 제조 방법에 관한 것이다. 이러한 방법으로 얻어진 가교제 화합물은 고흡수성 수지의 제조 과정에서, 열 분해 가능한 내부 가교제로서 바람직하게 사용될 수 있다. The present invention relates to a method for preparing a cross-linking agent compound that can be used for the production of a super absorbent polymer by a simple method and in a higher yield. The cross-linking agent compound obtained in this way can be preferably used as a thermally decomposable internal cross-linking agent in the manufacturing process of the super absorbent polymer.

A Method for Preparation of Allyl Alcohol

본 발명은 알릴알콜의 제조방법에 관한 것으로서, 보다 상세하게는 글리세롤과 포름산을 특수한 합성 조건에서 반응시켜, 액상 반응생성물 중의 알릴알콜의 함량을 획기적으로 높일 수 있고, 부산물인 알릴 포메이트 및 미반응 포름산을 최소화시킬 수 있는, 새로운 알릴 알콜의 제조 방법에 관한 것이다.

Use of 1, 2-dialkoxyalkane and -alkene

(57)【要約】本公報は電子出願前の出願データであるた め要約のデータは記録されません。

A kind of tobacco aromaticss formula of fresh breath and preparation method thereof

本发明提供一种清新口气的烟用香料配方及其制备方法，其烟用香料配方成分包括：茶叶提取物、黄连素、香芹菜素、香菜素、薄荷脑、陈皮粉、新植二烯、丙二醇、丁酸乙酯、乙酸乙酯、康酿克油、y‑癸内酯、丁香油、朗姆醚、乙基香兰素、云叶酊，剩余成分由食用酒精补足。由于茶叶提取物中茶多酚、黄连素、香芹菜素和香菜素的香味、薄荷脑、陈皮粉的芳香性挥发油均具有清新口气、清除口腔异味的效果，因此，本发明的烟用香料可以减少吸烟者口腔异味，达到清新口气的效果，避免造成他人困扰、影响自身形象。

Ruthenium/carbon-hydrogenation catalysts, their preparation and their use in the selective hydrogenation of unsaturated carbonyl compounds

Purification of hydroxy isobutylic acid

본 발명은 β-히드록시이소부티르산의 새로운 정제 방법에 관한 것으로, (a) β-히드록시이소부티르산을 포함하는 수성용액을 pH1.5~3.5에서 유기용매로 추출하여 유기용매층을 분리하는 공정; (b)분리된 유기용매층을 알카리용액으로 중화시켜 수층을 분리하는 공정; (c) 분리된 수층을 pH1.0~7.0에서 유기용매로 세척하는 공정; (d)세척한 수층을 pH1.5~3.5에서 유기용매로추출하여 유기용매층을 분리한 후 농축하여 β-히드록시이소부티르산의 농축액을 얻는 공정; (e)얻어진 β-히드록시이소부티르산 농축액을, 유기용매 중에서 또는 소량의 물이 혼재하는 유기 용매 중에서, 무기염기로 중화시켜 β-히드록시이소부티르산의 금속결정염을 제조하는 공정을 포함하여 구성되는 β-히드록시이소부티르산의 정제 방법에 관한 것이다. The present invention relates to a novel purification method of β-hydroxyisobutyric acid, which comprises: (a) extracting an aqueous solution containing β-hydroxyisobutyric acid with an organic solvent at a pH of 1.5 to 3.5 to separate an organic solvent layer. ; (b) neutralizing the separated organic solvent layer with an alkaline solution to separate the aqueous layer; (c) washing the separated aqueous layer with an organic solvent at pH 1.0-7.0; (d) extracting the washed aqueous layer with an organic solvent at pH 1.5-3.5, separating the organic solvent layer, and then concentrating to obtain a concentrate of β-hydroxyisobutyric acid; (e) comprising the step of neutralizing the obtained β-hydroxyisobutyric acid concentrate in an organic solvent or in an organic solvent in which a small amount of water is mixed with an inorganic base to prepare a metal crystal salt of β-hydroxyisobutyric acid It relates to a method for purifying β-hydroxyisobutyric acid. 본 발명에 의하면, 비교적 단순한 공정에 의하여 고순도의 β-히드록시이소부티르산을 금속염의 결정형태로 정제할 수 있으며, 정제된 β-히드록시이소부티르산은 금속 염의 형태로 산성 부위가 보호되어 있으므로 보존성이 개선되어 있고, 그대로 또는 간단한 산처리를 거쳐 β-히드록시이소부티르산으로 전환되어 합성 원료로 사용될 수 있다. According to the present invention, it is possible to purify high-purity β-hydroxyisobutyric acid in the form of a metal salt by a relatively simple process, and the purified β-hydroxyisobutyric acid is protected from acidic sites in the form of a metal salt, so that the preservability It is improved and can be converted to β-hydroxyisobutyric acid as it is or as a simple acid treatment and used as a synthetic raw material.