ОМЕГА-ГИДРОФТОРАЛКИЛОВЫЕ ЭФИРЫ, СПОСОБ ИХ ПОЛУЧЕНИЯ, ИСХОДНЫЕ КАРБОНОВЫЕ КИСЛОТЫ И ИХ ПРОИЗВОДНЫЕ И СПОСОБЫ С ИСПОЛЬЗОВАНИЕМ ЭФИРОВ (ВАРИАНТЫ)

Изобретение относится к новым жидким в нормальных условиях омега-гидрофторалкиловым эфирам, которые обладают свойствами поверхностно-активных веществ и могут быть использованы для вытеснения воды с поверхности, в композициях для удаления загрязнителя с изделия, в композициях для пожаротушения, для изготовления пенопласта, при пайке в паровой фазе. Эфиры соответствуют общей формуле I F-Rf-O(Rf'-O)nRf''-H, где Н - атом водорода в концевой группе СF3, Rf, Rf' и Rf'' - независимо выбраны из группы, состоящей из линейных незамещенных или замещенных перфторалкилом перфторалкиленовых групп, причем Rf имеет 4-9 атомов углерода в цепи, Rf' имеет 1-6 атомов углерода в цепи, Rf'' имеет 2-6 атомов углерода в цепи, n - целое число от 0 до 7, или при n, равном 0, Rf означает перфторциклоалкилзамещенную перфторалкиленовую группу с 6-10 атомами углерода, в которой один или более атомов углерода в Rf могут быть замещены атомами кислорода, Rf', Rf'' независимо выбраны из группы линейных незамещенных перфторалкиленовых ...

СПОСОБ ПОЛУЧЕНИЯ НИЗКОМОЛЕКУЛЯРНЫХ ЙОДИРОВАННЫХ ОРГАНИЧЕСКИХ ВЕЩЕСТВ И НИЗКОМОЛЕКУЛЯРНЫЕ ЙОДИРОВАННЫЕ ОРГАНИЧЕСКИЕ ВЕЩЕСТВА

Изобретение относится к способу получения низкомолекулярных йодированных органических веществ и полимеров, включающих эти вещества. Техническая задача - разработка более дешевого и безопасного способа получения низкомолекулярных йодированных органических веществ. Предложен способ получения одного или более йодированных органических веществ с молекулярной массой меньше 2000 (вещество S) с использованием (А) по меньшей мере одного вещества, генерирующего свободные радикалы, которое выбирают из пероксидов, диазосоединений, диалкилдифенилалканов, веществ, полученных из тетрафенилэтана, боранов и веществ-передатчиков цепи, содержащих по меньшей мере одну тиурамдисульфидную группу, (В) ненасыщенного вещества с этиленовой двойной связью, способного к присоединению свободного радикала к его этиленовой двойной связи и (С) молекулярного йода, который включает стадии, на которых по меньшей мере часть (А), по меньшей мере часть (В) и по меньшей мере часть (С) вводят в реактор и затем содержимое реактора ...

Способ получения гексафторизопропанола и фторметилгексафторизопропилового эфира (севофлурана)

Настоящее изобретение относится к способу получения фторметилгексафторизопропилового эфира (севофлурана), применяемого в качестве ингаляционного анастетика, а также к способу получения гексафторизопропанола. Один из вариантов способа получения севофлурана включает следующие стадии: (a) очистка смеси, содержащей гексафторацетон и более 120 ppm 1,1,1-трифтор-2,2-дихлорэтана в качестве примеси, с получением очищенного гексафторацетона, содержащего 120 ppm или менее 1,1,1-трифтор-2,2-дихлорэтана; (b) приведение водорода (Н) в контакт с очищенным гексафторацетоном в присутствии катализатора, посредством чего осуществляют гидрирование гексафторацетона с получением гексафторизопропанола, и (c) проведение реакции гексафторизопропанола, формальдегида и фторида водорода в присутствии кислоты Льюиса или кислоты Бренстеда. Настоящее изобретение позволяет получить целевые продукты за более короткий период времени. 3 н. и 20 з.п. ф-лы, 4 табл., 25 пр.

СПОСОБ ПОЛУЧЕНИЯ ПРОСТЫХ ПОЛИФТОРАЛКИЛОВЫХ ЭФИРОВ

Изобретение относится к способу получения простых полифторалкиловых эфиров формулы H(CF2)nCH2OR (n=2, 4, 6; R=н-Pr, н-Bu, изо-Bu, н-С5Н11, изо-С5Н11, н-С6Н13, С6Н11(циклогексил), RF (где RF=H(CF2)nCH2, n=2, 4, 6, 8), Ph, ArCH2 (где Ar=Ph, п-Cl-Ph, п-СН3О-Ph, м-NO2-Ph)) реакцией соответствующих спиртов или фенола с полифторалкилхлорсульфитами в присутствии растворителя при смешении реагентов при температуре -10 - -5°С. При этом спирты или фенол дозируют в раствор полифторалкилхлорсульфита в смеси с катализатором N,N-диметилформамидом при их мольном соотношении, равном 1:(1-1,1):(0,005-0,1) соответственно, реакцию ведут при 40-50°С в течение 4-6 ч, а выделяющиеся диоксид серы и хлористый водород отдувают инертным газом. Способ позволяет получить полифторалкиловые эфиры с высоким выходом и упростить процесс. 1 табл.

СПОСОБ ПОЛУЧЕНИЯ ПОЛИФТОРИРОВАННЫХ ЭФИРОВ

Изобретение относится к получению полифторированных эфиров формулы ROCF2CF2H, где R = CH3- или HCF2CF2CH2-. Способ осуществляют путем взаимодействия алифатического спирта с тетрафторэтиленом в присутствии катализатора. Процесс ведут в присутствии воды в количестве 30-40% от массы катализатора. В качестве катализатора используют гидроксид калия в количестве 1,2-2,0% от массы используемого спирта. Температура процесса 50-110oС, давление 9-16 кгс/см2. При получении тетрафторэтилтетрафторпропилового эфира HCF2CF2OCH2CF2CF2H процесс ведут в присутствии 2-10 мас.% метанола. Технический результат - увеличение выхода целевого продукта, сокращение количества используемого катализатора. 1 з.п. ф-лы.

ФИЗИОЛОГИЧЕСКИ ПРИЕМЛЕМЫЕ ЭМУЛЬСИИ, СОДЕРЖАЩИЕ ГИДРИДЫ ПЕРФТОРУГЛЕРОДНОГО ЭФИРА, И СПОСОБЫ ИХ ИСПОЛЬЗОВАНИЯ

Изобретение относится к области химико-фармацевтической промышленности и касается физиологически совместимых эмульсий, содержащих гидриды перфторуглеводородных эфиров. Изобретение заключается в том, что эмульсии имеют различные медицинские применения. В особенности они полезны как контрастная среда для таких способов медико-биологических исследований, как способы ядерного и19F-магнитного резонансов, ультразвукового и рентгеновского способов, способа компьютерной томографии, в качестве переносчиков кислорода или "искусственной" крови при лечении болезней сердца и сосудистых заболеваний, в качестве адьювантов при коронарной ангиопластике и в лучевой и химиотерапии рака. Изобретение обеспечивает желаемый уровень переноса кислорода, достаточно стабильно в жидком или незамороженном состоянии, быстро выводится из организма, чтобы избежать токсикации. 13 з.п. ф-лы, 1 табл.

СПОСОБ ПОЛУЧЕНИЯ (ГАЛО)ФТОРУГЛЕВОДОРОДА, α-ФТОРЭФИРЫ, СПОСОБ ИХ ПОЛУЧЕНИЯ

Изобретение относится к способу получения (гало) фторуглеводородов, используемых как охлаждающие агенты, вспенивающие агенты, растворители и пропелленты. Способ включает нагревание соответствующего α-фторэфира в первой фазе при повышенной температуре. α-Фторэфиры получают реакцией не-енолизируемого альдегида с образованием промежуточного соединения с реакцией последнего со спиртом или галогенирезующим агентом. Предлагаются также новые α-фторэфиры. Способ прост в осуществлении. Изобретение способствует поиску подходящих заменителей хлорфторуглеводородов. 4 с. и 24 з.п.ф-лы, 8 ил., 3 табл.

СПОСОБ ПОЛУЧЕНИЯ КОМПОЗИЦИИ, СОДЕРЖАЩЕЙ ОЧИЩЕННОЕ ФТОРСОДЕРЖАЩЕЕ ПРОСТОЕ ЭФИРНОЕ СОЕДИНЕНИЕ

Изобретение предлагает способ получения композиции, содержащей очищенное фторсодержащее простое эфирное соединение. Способ получения композиции, содержащей очищенное фторсодержащее простое эфирное соединение, предусматривает (A) реакцию в присутствии фторсодержащего простого эфирного соединения и фторсодержащего олефинового соединения. Фторсодержащее простое эфирное соединение представлено формулой (1): CHX1X2CF2OX3, где X1 и X2 являются одинаковыми или различными. Каждый представляет собой атом водорода, атом фтора или трифторметильную группу. X3 представляет C1-6 алкильную группу при условии, что оба X1 и X2 не являются трифторметильными группами. Фторсодержащее олефиновое соединение представлено формулой (2): CX1X2=CF(CF2)nOX3, где n равно 0 или 1, и X1, X2 и X3 являются такими, как определено выше, при условии, что когда X1 или X2 представляет собой трифторметильную группу, n равно 0. Оба X1 и X2 не являются трифторметильными группами, с галогенирующим агентом и/или окислителем для ...

СПОСОБ ПОЛУЧЕНИЯ ПЕРФТОР-2-МЕТИЛ-3-ПЕНТАНОНА И ПРОМЕЖУТОЧНЫХ СОЕДИНЕНИЙ

... 1. Способ получения перфтор-2-метил-3-пентанона, отличающийся тем, что в присутствии солей фторида и соединений простых эфиров, перфтор-2,3-эпоксид-2-метил-пентан превращают в перфтор-2-метил-3-пентанон путем реакции каталитической перегруппировки при температуре реакции 10-70°С;соль фторида выбирают из одного или из комбинации двух или более чем трех фторида лития, фторида натрия, фторида калия, фторида цезия и фторида алюминия;соединение простого эфира выбирают из одного или из комбинации двух или более чем трех диэтилового эфира, сульфолана, 15-краун-5 и 18-краун-6;мольное соотношение соединения простого эфира и солей фторида составляет 0,5~5,0:1;мольное отношение солей фторида и перфтор-2,3-эпокси-2-метил-пентана составляет 0,02~0,5:12. Способ получения перфтор-2-метил-3-пентанона по п. 1, отличающийся тем, что соль фторида выбирают из одного, двух или трех фторида калия, фторида цезия и фторида алюминия.3. Способ получения перфтор-2-метил-3-пентанона по п. 1 или 2, отличающийся тем ...

Способ получени перфторированных органических соединений

... 1. Способ получения перфторированных органических соединений электрохимическим фторированием их углеводородных аналогов в жидком фтороводороде на никелевых анодах в присутствии органической электролитической добавки, отличающийся тем, что в качестве органической электролитической добавки в электролит добавляют третичный алифатический и/или ароматический амин в количестве не менее 25% от исходного соединения. 2. Способ по п.1, отличающийся тем, что в качестве третичного алифатического амина берут амин общей формулы (RH)3 N, где RH - предельный или непредельный радикал, имеющий от 2 до 4 углеродных атомов и взятый из группы C2H5, С3Н7, С4Н9, С3Н5, а в качестве ароматического амина – C5H5N или его алкильное производное. 3. Способ по пп.1 и 2, отличающийся тем, что в качестве углеводородных аналогов перфторированных органических соединений берут соединения из группы алкилсульфофторидов, простых алкиловых эфиров, ароматических соединений. 4. Способ по пп.1-3, отличающийся тем, что в качестве ...

СПОСОБ ПОЛУЧЕНИЯ ФТОРУГЛЕВОДОРОДОВ ИЗ АЛЬФА ФТОРЭФИРОВ АЛЬФА -ФТОРЭФИРЫ И СПОСОБ ИХ ПОЛУЧЕНИЯ

Раскрывается способ получения (гало)фторуглеводорода, который включает нагревание альфа-фторэфира в паровой фазе при повышенной температуре. альфа-фторэфиры получают реакцией не-енолизируемого альдегида с фторводородом, чтобы образовать промежуточное соединение, и реакцией промежуточного соединения со спиртом или галогенирующим агентом. Предлагаются также новые альфа-фторэфиры.

СПОСОБ ПОЛУЧЕНИЯ ПРОСТОГО БИС (ФТОРМЕТИЛОВОГО) ЭФИРА И СПОСОБ ПОЛУЧЕНИЯ ДИФТОРМЕТАНА

Способ получения простого бис(фторметилового) эфира, при осуществлении которого предусмотрено взаимодействие формальде- гида с фтористым водородом в присутствии практически несмеши- вающегося с водой растворителя для этого эфира. Простой бис (фторметиловый) эфир можно подвергать конверсии в дифторметан, необязательно после отделения от растворителя, предпочтительнее нагреванием бис(фторметилового) эфира до повышенной температуры в присутствии металлического, металлоксидного, металлфторидного или металлоксифторидного катализатора.

Способ получения хлорметиловых эфиров спиртов

Оксиэтилированные -дигидроперфторспирты для синтеза морозостойких полиакрилатов

Способ получения хлорсодержащих ненасыщенных олигоэфиров

Способ получения простых хлорэфиров

Способ получения альфа,бета-диброметилалкиловых эфиров бромированием винилалкиловых эфиров

Способ получения альфа,бета,бета,бета-тетрахлорэтилариловых эфиров

Способ получения бромзамещенных эфиров гликолей

CПOCOБ ПOЛУЧEHИЯ ПOЛИФTOPAЛKИЛOBЫX ЭФИPOB ЭTИЛEHГЛИKOЛЯ

Способ получения дихлоргидринового эфира дифенилолпропана

Способ получения 2-бром-перфторэтилгипофторита

Способ получения 2-бром-перфторэтил- гипофторита Использование для производства фторэластомеров, которые вулканизируются перекисями. Продукт 2-бром-пер- фторэтилгипофторит БФ C2F5 ОВг. Реагент 1: бромдифторацетилфторид БФ С 2F 30 Вг реагент 2: фтор. Условия: комн. темп., жидкая фаза, инертный разбавитель, катализатор - фторид цезия, суспендированный в перфтор полиэфирном масле Выход 100% (ГЖХ) ...

Способ получения моно- или диполифторалкиловых эфиров гликолей

Способ получения хлорфторалкиловых эфиров

Flouro-halo-ethers of general formula: (R)nC(F)m-O-CAF-CAF2 wherein R is a partly or completely halogenated hydrocarbon, alkyl monoether or alkyl polyether radical, A is either chlorine or bromine, n is an integer selected between 1 and 2, m is an integer equal to 3-in. The value n = 2 comprises the compounds wherein C is a part of a cyclic ring.

Herstellung von Difluoressigsäurefluoride und von Ester der Difluoressigsäure

HERSTELLUNG VON BIS (FLUORMETHYL)ETHER UND/ODER DIFLUORMETHAN AUS FORMALDEHYD UND FLUORWASSERSTOFF

IN HOHEM MASSE FLUORIERTE, CHLORSUBSTITUIERTE ORGANISCHE VERBINDUNGEN ENTHALTENDE EMULSIONEN UND METHODEN ZU DEREN HERSTELLUNG UND VERWENDUNG

VERFAHREN ZUR DEHALOGENIERUNG VON ETHERN

VERFAHREN ZUR HERSTELLUNG SUBSTITUIERTER CYCLOPROPANCARBALDEHYDE.

METHODS OF SYNTHESIZING HEXAFLUOROISOPROPANOL FROM IMPURE MIXTURES AND SYNTHESIS OF A FLUOROMETHYL ETHER THEREFROM

Hydrofluorether mit mindenstens einer hydrierten (-ocfx'ch3)-Endgruppe (x'=f,cf3), Verfahren zur ihrer Herstellung

Verfahren zur Herstellung eines 1, 1, 3-Tributoxy-2-halogenpropans

Verfahren zur Herstellung von Perfluoropolyethern von kontrollierbarem Molekulargewicht, welche Perfluoralkyl- oder Perfluorchloralky-Endgruppen enthalten.

VERFAHREN ZUR HERSTELLUNG VON FLUORMETHYLHEXAFLUORISOPROPYLETHER

Verfahren zur Herstellung von 1,2,2,2-Tetrafluorethyl-Difluormethyläther.

1.2.4-TRIAZOLIDINE-3.5-DIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

SCHAEDLINGSBEKAEMPFUNGSMITTEL

PROCESS FOR PREPARING ADDUCTS OF ALCOHOLS, ETHERS AND ESTERS WITH 1,2-DICHLORODIFLUOROETHYLENE

POLYHALOMETHYL ETHYL ETHERS, THEIR PRODUCTION, AND THEIR USE AS ANAESTHETICS

... 1285110 Inhalation anaesthetic AIRCO Inc 4 Dec 1970 57730/70 Heading A5B [Also in Division C2] An inhalant anaesthetic composition comprises oxygen and a compound of the general formula: in which one X radical is Cl and the other is H.

Process of preparing 1,2,2,2-tetrafluoroethyl-difluoromethyl ether

CF3CHFOCHF2 useful as an anaesthetic is formed by fluorinating CF3CHXOCHF2, wherein X is a halogen atom other than fluorine atom, by an alkali metal fluoride in an aprotic polar solvent in the presence of a phase-transfer catalyst such as tetramethylammonium chloride or 18-crown-6-ether. The reaction proceeds under mild conditions, and the selectivity to the aimed compound is very high. The aimed compound can easily be separated from unreacted starting compound since the boiling point of the starting compound sufficiently differs from that of the aimed compound.

HEMIACETALS OF BROMAL AND HYDROXY COMPOUNDS AND A METHOD OF PREPARING THEM

... 1361134 Bromal hemiacetals KAZANSKY VETERINARNY INSTITUT IMENI NE BAUMANA 17 Aug 1972 38317/72 Heading C2C Novel bromal hemiacetals of the general formula [Br 3 CCH(OH)O] n R, wherein R is an alkyl group substituted by an aryl, nitro, cyano, hydroxyl, vinyl or #-hydroxyethoxy group or a cycloalkyl group and n is 1 or R is a dihydric alcohol residue and n is 2, are prepared by reacting bromal with an alcohol of the general formula R(OH) n at a temperature not exceeding 70‹ C. Pharmaceutical compositions having bactericidal and fungicidal activity comprise, as active ingredient, a bromal hemiacetal of the above general formula, together with a suitable carrier.

Fire and explosion suppression

Improvements in or relating to difunctional ethylenic compounds

Novel compounds of the formula ROCH2CH(R1)-A1(Z-A11)n-R11 wherein R represents hydrogen, C1- 6 alkyl or C2- 7 alkanoyl; R1 represents hydrogen or C1- 6 alkyl; A1 and A11 represent -CS-, -CO-, -SO-, -SO2- or R111 represents a substituted or unsubstituted alkyl or aralkyl radical; Z represents alkylene, aralkylene, (in which Y is a divalent organic radical), the residue of a heterocyclic diamine (in which the two nitrogen atoms are part of the heterocyclic ring D). n is 0 or 1; and R11 is -C(R1)=CHR1, are prepared by reacting a compound of the formula (where X represents a halogen atom) with an alkali compound having a dissociation constant greater than 10-5. Alternatively, some of the above compounds may be obtained by reacting a compound of the formula CH(R1)=C(R1)COX with compounds of the formula ROCH2CH(R1)CON(R1)-Yf-NH(R1) (where b is 0 or 1) or ROCH2CH(R1)SO2NH(R1); or by reacting a compound ...

15-SUBSTITUTED PROSTANOIC ACIDS AND ESTERS

... 1421946 Prostaglandins AMERICAN CYANAMID CO 29 June 1973 [24 July 1972] 31235/73 Heading C2C] The invention comprises prostaglandins of the Formula A wherein m is 3 to 9, R 1 is C 2-7 alkyl, R 2 is H or C 1-12 alkyl, X is halogen, SH, -N 3 , NH 2 , -SCN, C 1-4 alkanoylthio, or C 1-4 alkylsulphonyloxy, with the proviso that when X is C 1-4 alkylsulphonyloxy then R 2 is C 1-12 alkyl, and pharmaceutically acceptable salts thereof when R 2 is H and their preparation. The compounds are prepared by reacting compounds of the Formula IV wherein R1 2 is C 1-12 alkyl with C 1-4 alkylsulphonyl halides, reacting the resulting compounds of Formula A above in which R 2 is C 1-12 alkyl and X is C 1-4 alkylsulphonyloxy with metal halides sodium azide, potassium thiocyanate or potassium thiolalkanoates to give compounds of the above A in which R 2 is C 1-12 alkyl and X is halogen, C 1-4 alkanoylthio, -N 3 or -SCN, and if desired catalytically hydrogenating the compounds in which X is -N 3 to obtain ...

Process for Recovering Heptafluoroisopropyl 2'-Iodotetrafluoroethyl Ether

... 1,195,857. Recovering heptafluoro-isopropyl- 21-iodo-tetrafluoroethyl ether. ALLIED CHEMICAL CORP. 25 Sept., 1967 [27 Sept., 1966], No. 43573/67. Addition to 1,165,912. Heading C2C. Heptafluoro - isopropyl - 21- iodotetrafluoroethyl ether is recovered from a mixture thereof with acetonitrile in which the molar ratio of the acetonitrile to the other component is at least 2 : 1, by (i) fractionally distilling an azeotrope of the two components from the mixture and (ii) washing with water the distillate from (i) to extract the acetonitrile therefrom.

Process for the production of fluoromethyl hexafluoroisopropyl ether

NOVEL 2-ALKYL-4-OXA-STEROIDS AND A PROCESS FOR THE MANUFACTURE THEREOF

... 1,207,048. 2-Alkyl-4-oxa-steroids. F. HOFFMAN-LA ROCHE & CO. A.G. 1 Nov., 1968 [2 Nov., 1967], No. 51935/68. Heading C2C. The invention comprises compounds of formula wherein m is 1 or 2, R1 is C 1-5 primary alkyl, R3, R4, R7 and R8 are each H or C 1-8 alkyl, R5 is C 1-8 alkyl, R2 is H, R6 is OH, or R2 and R6 together represent an extra bond, Z is carbonyl or C(#-OR9)(-R10) wherein R9 is H or C 1-7 acyl and R10 is H or C 1-5 hydrocarbyl, and the wavy lines indicate or #-configurations. The compounds wherein R2 + R6 represent an extra bond are prepared by acid cyclization of compounds of formula wherein R11 is C 1-8 alkoxy, and are converted to the compounds wherein R2 is H and R6 is OH by treatment with aqueous acid. The conversion of compounds of Formula I into steroids and the preparation of compounds of Formula II are ...

POLYOXYETHYLENE GLYCOL DIHALIDES

... 1508511 Polyoxyethylene dihalides GAF CORP 13 Jan 1976 [5 June 1975] 01263/76 Heading C2C [Also in Division C3] Mixtures of polyoxyethylene dihalides comprises components each of which corresponds to the general formula XCH 2 CH 2 (OCH 2 CH 2 ) n OCH 2 CH 2 X (I) in which n is 3-600, x is halogen and the mixture has an average molecular weight of 275- 30,000. X is preferably Cl or Br. I may be prepared by reacting thionyl chloride with polyethylene glycols.

PROCESS FOR PREPARING PERFLUORINATED ETHERS

Selective fluorination

Some at least of the bromine atoms in a compound AB (as defined below) are replaced by fluorine by treating AB with BrF3 plus liquid bromine at a temperature not above 60 DEG C.; A is C1- 5 aliphatic residue containing at least one bromine atom, the remaining substituents being H, F or Cl; and B is H. Cl, NO2, CN, COF, CHO, -OCOR, -COOR, -OR or -COR, where R is C1- 3 alkyl. Examples prepare (1) CF2Br.CHBrF or CF3.CHBrF from CF2Br.CHBr2; (2) CH3.CHBrF from CF3.CHBr2; CF3.CH2F from CF3.CH2Br; CF3.CHBrF and CF3.CHF3 from CHBrF.CBr2F; CHF2.CHBr2 and CHBrF.CHBr2 from CHBr2.CHBr2; (3) CH2F. CH2F from CH2Br.CH2Br; (4) CH3.CH2F from CH3.CH2Br; (5) CHClF.CHClF from CHBrCl.CHBrCl; (6) CF2Cl (CH2)4F from CF2Cl(CH2)4Br; (7) CH3OCF2.CHBrF and CH3OCF2.CHF2 from CH3OCF2.CHBr2; (8), (9) CF2Br.NO2 and CFBr2.NO2 from CBr3.NO2; (10) CHBrF.COOCH3 from CHBr2.COOCH3. Other starting materials are listed.

Processes for the preparation of derived from the dihydrotriazine.

MORE PERFLUOROPOLYETHER

PROCEDURE FOR THE PRODUCTION OF HYDROFLUORETHERN

PROCEDURE FOR THE PRODUCTION OF NEW ONES ARYLATHERN

PROCEDURE FOR the PRODUCTION OF 1-CHLOR-2,2,2-TRIFLUORATHYLDIFLUORMETHYLATHER

PROCEDURE FOR the PRODUCTION OF NEW ONE 1,2,2,2-TETRAFLUORATHYLATHERN

PROCEDURE FOR THE PRODUCTION OF NEW SUBSTITUTED ISOXAZOLEN AND OF CIS AND/OR TRANS ISOMERS OF IT

CHIRALE 1,5-DIIODO-2-METHOXY OR BENZYLOXY INTERMEDIATE PRODUCTS

OIL IN WATER EMULSION, WHICH CONTAINS MORE PERFLUOROPOLYETHER, COMPOSITION THESE CONTAINS, MANUFACTURING METHOD AND KOSMETOLOGI AND DERMATOLOGI USE

STABILIZATION OF FLUORINE CARBON EMULSIONS

PRODUCTION OF TO (FLUORINE METHYL) ETHER AND/OR DIFLUORMETHAN FROM FORMALDEHYDE AND HYDROGEN FLUORIDE

PROCEDURE FOR THE PRODUCTION OF PERFLUORIERTEN BROMINE ALKANES OR ETHERGRUPPEN ABSTENTION PERFLUORIERTEN BROMINE ALKANES

PROCEDURE FOR in-SITu-PRODUCTION OF NSUBSTITUIERTEN 2-HALOACETANILIDEN.

PROCEDURE FOR THE PRODUCTION OF FLUORCARBONPOLYÄTHERN.

META SUBSTITUTING DIOXYALKYLCARBONSAEUREN, ESTER, - AMIDES AND - SALTS OF DIPHENYLAETHERN.

NEW AMINODERIVATE the 5 (2-HYDROXYSTYRYL) ISOXAZOLS, PROCEDURES FOR YOUR PRODUCTION AND THESE CONTAINING THERAPEUTIC MEANS.

SYNTHESIS OF DIFLUORMETHYLMETHYLETHER

PROCEDURE FOR AUFREINIGUNG OF FLUORINE METHYL HEXAFLUORISOPROPYL ETHER

PROCEDURE FOR the PRODUCTION OF NEW ONE 1,2,2,2-TETRAFLUORATHYLATHERN

PROCEDURE FOR the PRODUCTION OF NEW ONE 2,2,2-TRIFLUOR-1-CHLORATHYL-ATHERN

A PROCEDURE FOR THE PRODUCTION OF HALOGENIERTEN ETHERN

PROCEDURE FOR THE PRODUCTION OF FLUOROCARBONS, USE AS COOLING AGENTS AS WELL AS LUBRICANT FOR MAGNETIC RECORDING MEDIA

USE OF TO A LARGE EXTENT FLUORIDATED CONNECTIONS AS HEAT DISTRIBUTION MEDIA

AS CLEANING AGENT USABLE SOLVENTS

POLYMERISING PERFLUOROPOLYETHERS BY METAL COMPOUNDS

CHEMICAL PROCESSES

COTELOMERS OF VINYLIDENE FLUORIDE WITH FLUORINATED OLEFINS, AND PROCESS FOR THEIR PREPARATION

PROSTANOIC AND PROSTENOIC ACID DERIVATIVES AND INTERMEDIATES

Process for preparing hydrofluoroethers

NOVEL ETHER

Fluoroiodocarbon blends as CFC and halon replacements

Compositions useful as refrigerants

POLYOL MONOETHERS OF DICYCLOPENTADIENE

Compositions useful as refrigerants

INSECT CONTROL.

PRODUCTION OF FLUOROMETHYL 2,2,2-TRIFLUORO-1-(TRIFLUOROMETHYL)ETHYL ETHER

An improved process for preparing flouromethyl2,2,2-trifluoro-1- (trifluoromethyl) ethyl ether (sevoflurane) by reacting 1,1,1,3,3,3-hexafluoro-2-propanol with formaldehyde and hydrogen fluoride either (a) under distillation conditions or (b) in the presence of or with the subsequent addition of a solvent capable of selectively extracting sevoflurane.

ANESTHETIC COMPOSITION AND METHOD OF USING THE SAME

The present invention is directed to an anesthesia inducing composition comprising a mixture of oxygen gas and an anesthesia inducing effective amount of a compound 2-(difluoro- methoxy)-1,1,1,2-tetrafluoroethane having the formula The present invention is also directed to methods of inducing and/or maintaining anesthesia by administering the composition in sufficient amounts to warm blooded animals.

METHOD FOR THE DEHALOGENATION OF ETHERS

Methods for the dehalogenation or various haloethers are disclosed, comprising providing a haloether having the formula CX'3-(CY2)n-O-CZ2-CX3 in which X', Y, Z and X are specifically disclosed combinations of hydrogen, fluorine chlorine and bromine such that the molecule includes at least one reducible group, but where both portions of any ethyl groups present are not reducible. Dehalogenation of these haloethers is carried out by contacting same with a hydrogen donor comprising an amine, preferably a primary or secondary amine or a primary, secondary or tertiary alkanol amine. The amine is preferably used in combination with a catalyst, such as a varivalent metal or a salt thereof, such as copper or a copper salt.

AMINO DERIVATIVES OF 5-(2-HYDROXYSTYRYL)-ISOXAZOLE, THEIR PREPARATION AND THERAPEUTIC FORMULATIONS CONTAINING THESE COMPOUNDS

The prevent invention is directed to novel aminopropanol derivatives of 5-(2-hydroxystyryl)-isoxazole of the formula (I) (I) where n is 1 or 2, o is 1, 2 or 3, R1 and R2 are each hydrogen or straight-chain or branched alkyl of 1 to 5 carbon atoms, R3 is hydrogen, hydroxyl, halogen alkyl, alkoxy or alkylthio of 1 to 5 carbon atoms, (the last-mentioned three groups each being unsubstituted, or mono-, di or tri-substituted by halogen or mono-substituted by hydroxyl or alkoxy of 1 to 3 carbon atoms), alkenyl, alkynyl, alkynyloxy or cycloalkoxy, each of 2 to 6 carbon atoms in the alkyl and of 3 to 8 carbon atoms in the ring or amino which is unsubstituted or is monoor di-substituted by alkyl of 1 to 5 carbon atoms, and if o is 2 or 3, the R3's may be identical or different, or R3 is methylenedioxy or alkylene of 3 or 4 carbon ? o , and R4 is alkyl of 1 to 4 carbon atoms, and their addition salts with acids. This invention is also concerned with the preparation of said novel compounds, ...

PROCESS FOR THE IN-SOLVENT, IN-SITU GENERATION OF HALOALKYL ALKYL ETHERS USEFUL TO PRODUCE N- SUBSTITUTED-2-HALOACETANILIDES

The present invention is directed to a process for the preparation of certin N-substituted -2-haloacetanilides via the reaction of a secondary 2-haloacetanilide with a haloalkyl ether, particularly, halomethyl ethers, which comprises forming the ether in situ by the in-solvent reactin of an alcohol, formaldehyde or other aldehyde and an acid halide to produce high purity haloalkyl ethers, while decreasing the concentration of undesirable bis by products, as for example bis(chloromethyl) ether. The ether formed in situ thereafter reacts with the secondary 2-haloacetanilide in the presence of a phase transfer catalyst and base to form the N-substituted-2-haloacetanilide.

2,2,2-TRIFLUORO-1-CHLOROETHYL ETHERS AND PROCESS FOR PREPARING THEM

2,2,2-TRIFLUORO-1-CHLOROETHYL ETHERS AND PROCESS FOR PREPARING THEM Abstract of the disclosure: 2,2,2-Trifluoro-1-chloroethyl ethers and process for pre-paring them; the compounds are useful inhalation anesthetics which are distinguished by shorter recovery times.

2-CHLORO-1,2,2-TRIFLUOROETHYL DIFLUOROMETHYL ETHER

STABLE ETHYLENE INHIBITING COMPOUNDS AND METHODS FOR THEIR PREPARATION

A method to inhibit the ethylene response in plants with cyclopropene compounds by first generating stable cyclopropane precursor compounds and then converting these compounds to the gaseous cyclopropene antagonist compound by use of a reducing or nucleophilic agent.

FLUORINATED COMPOUNDS CONTAINING FUNCTIONAL GROUPS

THE USE OF SUBSTANTIALLY FLUORINATED COMPOUNDS AS HEAT TRANSFER AGENTS

... of the disclosure The use of substantially fluorinated compounds as heat transfer agents Non-flammable, substantially fluorinated compounds from the series of alkanes and/or dialkyl ethers are suitable as heat transfer agents, in particular as coolant or insulating medium, especially for evaporative cooling. These compounds can also be employed in a mixture with small amounts of intrinsically flammable liquids, in which case lower alkanols are preferred.

MORPHOLINYL DERIVATIVES OF DOXORUBICIN AND PROCESS FOR THEIR PREPARATION

Morpholinyl derivatives of doxorubicin having formula (A), in which X represents a linear or branched C2-C6 alkyl group or a benzyl group -CH2C6H5 and which have (S) or (R) configuration at carbon atom C-2" of the morpholino ring, are antitumor agents.

FLUOROIODOCARBON BLENDS AS CFC AND HALON REPLACEMENTS

A new set of effective, environmentally safe, nonflammable, low-toxicity refrigerants, solvents, foam blowing agents, propellants, and firefighting agents is disclosed. The agents are clean, electrically nonconductive, and have short atmospheric lifetimes, zero ozone-depletion potential, and low global warming potentials. The agents comprise at least one fluoroiodocarbon agent satisfying the general formula: CaHbBrcCldFeIfNgOh, wherein a is between and including 1 and 8; b is between and including 0 and 2; c, d, g and h are each between and including 0 and 1; e is between and including 1 and 18; and f is between and including 1 and 2, either neat or mixed with additives selected from the group consisting of: alcohols, esters, ethers, fluoroethers, hydrocarbons, hydrofluorocarbons, and perfluorocarbons.

PROCESS FOR THE SYNTHESIS OF HEXAFLUOROISOPROPYL ETHERS

A method of synthesizing 1,1,1,3,3,3-hexafluoroisopropyl ether compounds, including, or such as sevoflurane, from methoxymalononitrile, a compound also known as .alpha.,.alpha.-dicyanomethyl methyl ether, and having the formula (CN)2CHOCH3, and having the chemical structure (I).

FLUORINATED ETHER COMPOUND, FLUORINATED ETHER COMPOSITION, COATING LIQUID, ARTICLE AND ITS PRODUCTION METHOD

To provide a fluorinated ether compound capable of forming a surface layer excellent in initial water/oil repellency, fingerprint stain removability, abrasion resistance and light resistance; a fluorinated ether composition and a coating liquid containing the fluorinated ether compound; an article having a surface layer excellent in initial water/oil repellency, fingerprint stain removability, abrasion resistance and light resistance and a method for producing it. A fluorinated ether compound having a poly(oxyperfluoroalkylene) chain having a unit (α) which is an oxyperfluoroalkylene unit having 5 or 6 carbon atoms, and a unit (β) which is an oxyperfluoroalkylene unit having at most 4 carbon atoms, and having at least one of a hydrolysable silyl group and a silanol group on at least one terminal of the poly(oxyperfluoroalkylene) chain via a linking group. 1. A fluorinated ether compound having a poly(oxyperfluoroalkylene) chain having a unit (α) which is an oxyperfluoroalkylene unit having 5 or 6 carbon atoms , and a unit (β) which is an oxyperfluoroalkylene unit having at most 4 carbon atoms , and having at least one of a hydrolysable silyl group and a silanol group on at least one terminal of the poly(oxyperfluoroalkylene) chain via a linking group.2. The fluorinated ether compound according to claim 1 , wherein in the poly(oxyperfluoroalkylene) chain claim 1 , the proportion of the number of the unit (α) to the total number of the unit (α) and the unit (β) is from 0.02 to 0.5.3. The fluorinated ether compound according to claim 1 , wherein the poly(oxyperfluoroalkylene) chain contains a structure having the unit (α) and the unit (β) alternately arranged.4. The fluorinated ether compound according to claim 1 , wherein the unit (α) is (CFCFCFCFCFO) or (CFCFCFCFCFCFO).5. The fluorinated ether compound according to claim 1 , wherein the unit (β) is (CFO) or (CFCFO).6. The fluorinated ether compound according to claim 1 , which is a compound represented by the ...

METHODS, SYSTEMS, AND ASSEMBLIES FOR COOLING AN ELECTRONIC COMPONENT

Methods, systems, and assemblies for cooling an electronic component are disclosed. A heat sink assembly includes first and second substrates. The first substrate is in thermal contact with the electronic component. A primary channel is formed in the second surface of the first substrate. The primary channel is configured to direct cooling fluid for cooling the electronic component. An array of primary cooling fluid fins is positioned within the primary channel. The array of primary cooling fluid fins includes upstream solid fins and downstream open fins each having an upstream opening and downstream sidewalls. The secondary channel is formed within the second surface of the second substrate and is configured to direct partially heated cooling fluid away from the electronic component. An array of secondary cooling fluid fins is positioned within the secondary channel downstream. An enclosing layer seals the secondary channel. 1. A heat sink assembly for cooling an electronic component , said assembly comprising:a first substrate including first and second surfaces, said first surface being in thermal contact with said electronic component;a primary channel formed in said second surface of said first substrate, said primary channel being configured to direct cooling fluid for cooling said electronic component;an array of primary cooling fluid fins positioned within said primary channel, said array of primary cooling fluid fins including upstream solid fins and downstream open fins each including an upstream opening and downstream sidewalls;a second substrate including first and second surfaces with said first surface of said second substrate positioned in thermal contact with said second surface of said first substrate, said second substrate including cooling fluid conduits having upstream and downstream ends and each being formed through said second substrate from said upstream end at said first surface to said downstream end at said second surface;a secondary ...

BIS(1,1-DICHLORO-3,3,3-TRIFLUOROPROPYL) ETHER AND PROCESS FOR PREPARING THE SAME

The present invention provides a symmetrical ether compound which is chlorinated in the α position and which is useful as an intermediate for medicine and pesticides and as a raw material or a synthetic intermediate for producing a fluorine-containing compound, in particular a bis(1,1-dichloro-3,3,3-trifluoropropyl)ether represented by formula [1] which is obtained by chlorinating a bis(3,3,3-trifluoropropyl)ether. This bis(1,1-dichloro-3,3,3-trifluoropropyl)ether is produced by chlorinating, preferably under ultraviolet light irradiation, a bis(3,3,3-trifluoropropyl)ether. This invention relates to bis(1,1-dichloro-3,3,3-trifluoropropyl) ether and a process for preparing the same.Non-patent documents 1 to 3 below disclose an ether compound having a 1,1,3,3,3-pentafluoropropyl group which is analogous to the ether compound of the invention. However, these documents have no mention of a symmetrical ether compound having its α-positions chlorinated like the ether compound of the invention.Non-patent document 1: 71, 2432 (1949)Non-patent document 2: 72, 1860 (1950)Non-patent document 3: 52(1), 71-85 (1978)An object of the present invention is to provide a symmetrical ether compound having the α-positions chlorinated that is useful as an intermediate of pharmaceuticals and agricultural chemicals or a starting material or an intermediate for synthesizing fluorine-containing compounds.The inventor has conducted extensive study to solve the above problem and as a result succeeded in synthesizing a novel symmetrical ether compound having the α-positions chlorinated and found that the ether compound accomplishes the above object of the invention. The invention has been completed based on this finding.The invention provides bis(1,1-dichloro-3,3,3-trifluoropropyl) ether represented by formula (1):The invention also provides a process for preparing bis(1,1-dichloro-3,3,3-trifluoropropyl) ether represented by formula (1). The process comprises chlorinating bis(3,3,3- ...

Cryo-Light Microscope and Immersion Medium for Cryo-Light Microscopy

Ethoxy-nonafluorobutane (CFOCH) is used as an immersion medium for immersing an immersion objective of a cryo-light microscope. The cryo-light microscope comprising an immersion objective, a front lens mount holding a front lens of the immersion objective, a sample holder and a cold stage carrying the sample holder further has a heating device coupling a heat flow into the front lens mount. 1. An immersion medium for immersing an immersion objective in light microscopy , wherein the immersion medium is essentially made of hydrofluoroether.2. The immersion medium of claim 1 , wherein the hydrofluoroether is selected from ethoxy-nonafluorobutane (CFOCH) and methoxy-nonafluorobutane (CFOCH).3. The immersion medium of claim 2 , wherein the ethoxy-nonafluorobutane (CFOCH) is made of at least one of (CF)CFCFOCH(CAS No. 163702-06-5) and CFCFCFCFOCH(CAS No. 163702-05-4).4. A use of a cryogenic liquid essentially made of hydrofluoroether as an immersion medium for immersing an immersion objective in light microscopy.5. The use of claim 4 , wherein the hydrofluoroether is selected from ethoxy-nonafluorobutane (CFOCH) and methoxy-nonafluorobutane (CFOCH).6. The use of claim 5 , wherein the ethoxy-nonafluorobutane (CFOCH) is made of at least one of (CF)CFCFOCH(CAS No. 163702-06-5) and CFCFCFCFOCH(CAS No. 163702-05-4).7. The use of claim 4 , wherein a sample to be imaged is kept at a cryogenic temperature in the light microscopy.8. The use of claim 7 , wherein the sample to be imaged is kept at a cryogenic temperature in a range from −130° C. to −145° C.9. The use of claim 4 , wherein a heat flow is coupled into the immersion fluid at a front lens mount for a front lens of the immersion objective.10. The use of claim 9 , wherein a backside of the front lens is purged with dry nitrogen.11. The use of claim 9 , wherein the heat flow is directed into a cold stage carrying a sample holder holding the sample.12. A cryo-light microscope comprising:an immersion objective,a sample ...

Production Method for 1,2,2,2-Tetrafluoroethyl Difluoromethyl Ether (Desflurane)

Fluoral is obtained by gas-phase fluorination of chloral in the presence of a catalyst and then reacted with trimethyl orthoformate, thereby readily forming 1,2,2,2-tetrafluoroethyl methyl ether as an intermediate for production of desflurane. 1,2,2,2-Tetrafluoroethyl difluoromethyl ether (desflurane) is produced with high yield from the thus-formed 1,2,2,2-tetrafluoroethyl methyl ether by chlorination and fluorination. This method enables efficient industrial-scale production of desflurane useful as an inhalation anesthetic 2. The production method according to claim 1 , wherein the catalyst used in the first step is a metal compound-supported catalyst having claim 1 , supported on a metal oxide or activated carbon claim 1 , a metal compound containing at least one metal selected from the group consisting of chromium claim 1 , titanium claim 1 , manganese claim 1 , iron claim 1 , nickel claim 1 , cobalt claim 1 , magnesium claim 1 , zirconium and antimony.3. The production method according to claim 2 , wherein the metal compound is at least one kind of metal halide or metal oxyhalide selected from the group consisting of a fluoride claim 2 , a chloride claim 2 , a fluorochloride claim 2 , an oxyfluoride claim 2 , an oxychloride and an oxyfluorochloride of the at least one metal.4. The production method according to claim 2 , wherein the metal oxide is at least one kind selected from the group consisting of alumina claim 2 , zirconia claim 2 , titania claim 2 , chromia and magnesia.5. The production method according to claim 1 , wherein the 2 claim 1 ,2 claim 1 ,2-trifluoroacetaldehyde obtained in the first step is used as it is claim 1 , without purification operation claim 1 , as a raw material in the second step.6. The production method according to claim 1 , wherein claim 1 , in the second step claim 1 , the reacting is conducted without the use of an organic solvent.7. The production method according to claim 1 , wherein the radical initiator used in the third ...

Synthesis of Fluorinated Ethers

데스플루란과 같은 불소화된 에테르를 제조하는 방법은 크로미아 촉매의 존재하에 증기상으로 이소플루란과 같은 상응하는 염소화된 에테르를 무수 불화수소와 반응시킴을 포함한다. 본 요약서는 조사자 또는 기타 독자가 기술 명세서의 대상물을 빨리 확인할 수 있는 요약서를 요구하는 규칙을 충족시키기 위해 제공되는 것임을 강조한다. 첨부된 청구항의 범위 또는 의미를 해석하거나 제한하는데 사용되지 않는 것으로 이해하면서 제출된 것이다. 37 CFR § 1.72(b) Methods of preparing fluorinated ethers such as desflurane include reacting a corresponding chlorinated ether such as isoflurane with anhydrous hydrogen fluoride in the vapor phase in the presence of a chromia catalyst. It is emphasized that this summary is provided to satisfy the rules requiring an investigator or other reader to quickly identify the subject matter of the technical specification. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the appended claims. 37 CFR § 1.72 (b)

Refining method of chloromethyl hexafluoroisopropyl ether

本发明涉及一种氯甲基六氟异丙醚的精制方法。具体而言，该方法包括在蒸馏时加入稳定剂，以防止产品氯甲基六氟异丙醚的降解。由于阻止了酸性气体等降解产物的产生，精制产品的纯度提高，精制设备免于腐蚀，生产成本降低，生产效率得到提高。

Bis(1,1-dichloro-3,3,3-trifluoropropyl)ether and method for producing same

본 발명은 의약·농약의 중간체로서, 또한 함불소 화합물의 제조 원료 또는 합성 중간체로서 유용한, α위치가 염소화된 대칭 에테르 화합물을 제공하는 것이며, 구체적으로는 비스(3,3,3-트리플루오로프로필)에테르를 염소화함으로써 얻어지는, 하기 식[1]로 표시되는 비스(1,1-디클로로-3,3,3-트리플루오로프로필)에테르를 제공하는 것이다. 상기 비스(1,1-디클로로-3,3,3-트리플루오로프로필)에테르는 비스(3,3,3-트리플루오로프로필)에테르를 염소화, 바람직하게는 자외선 조사하에서 염소화함으로써 제조된다. The present invention provides a symmetrical ether compound which is chlorinated at the? -Position, which is useful as a raw material for synthesis of a fluorinated compound or as an intermediate for medicines and pesticides and also as a synthetic intermediate, and specifically includes bis (3,3,3-trifluoro (1,1-dichloro-3,3,3-trifluoropropyl) ether represented by the following formula [1], which is obtained by chlorinating an ether represented by the following formula [1]. The bis (1,1-dichloro-3,3,3-trifluoropropyl) ether is prepared by chlorinating bis (3,3,3-trifluoropropyl) ether, preferably under ultraviolet irradiation.

METHOD FOR PRODUCTION OF FLUORINATED HYDROCARBONS FROM α FLUOROETHERS, a-FLUOROETHER AND METHOD FOR PRODUCTION THEREOF

Раскрывается способ получения (гало)фторуглеводорода, который включает нагревание альфа-фторэфира в паровой фазе при повышенной температуре. альфа-фторэфиры получают реакцией не-енолизируемого альдегида с фторводородом, чтобы образовать промежуточное соединение, и реакцией промежуточного соединения со спиртом или галогенирующим агентом. Предлагаются также новые альфа-фторэфиры.

Novel oxahydrofluoroether compound, preparation method and application

本发明涉及氧杂氢氟醚化合物和制备新型氧杂氢氟醚化合物的方法以及氧杂氢氟醚化合物的应用。所述氧杂氢氟醚化合物是用通式CF 3 O(CF 2 O) m CF 2 CF 2 R表示的化合物，所述R为OR 1 、(OCF(CF 3 )CF 2 ) n OR 2 或OCF 2 CF 2 OR 3 ，R 1 、R 2 、R 3 为C 1 ‑C 3 直链或支链烷基。本发明设计的新型氧杂氢氟醚结构中含氧元素高，具有极低的表面张力，比其他氢氟醚溶剂具有更强的渗透性，应用于清洗剂可确保彻底清洁；同时，氧杂氢氟醚由于其含氧量高，大气寿命短，容易降解为CO 2 和氟化盐，GWP值(温室效应潜值)较低。新型氧杂氢氟醚在防指纹液稀释剂、稀释含氟处理剂、设备部件中除去污染物、制备泡沫塑料、蒸汽相焊接、传递热、在基底上沉积涂层、切割或研磨加工方面有良好的应用。

Process for the production of halogenated, aliphatic compounds from compounds with polymethylene oxide rings

Preparation method hybrid-fluorinated non-ionic surfactant

According to the present invention, disclosed is a method for producing a hybrid fluorine-based nonionic surfactant, capable of producing a high-purity material in a high yield.

Method for producing fluorohalogen ether

Novel alkylhalide compounds and method for preparing the same

The present invention relates to a novel alkyl halide compound and a process for preparing the same. The alkyl halide compound according to the present invention is applied to all polymers and monomers used in organic semiconductors, and thus the organic semiconductor material into which the novel alkyl group is introduced has a solubility And various solvents are added to facilitate the production of devices through solution processes such as spin coating, die casting, and printing, and the device characteristics can be improved by controlling the shape and crystallinity of the film.

FLUORURATION PROCESS IN LIQUID PHASE OF UNSATURATED COMPOUNDS

New perfluoropolyethers

New perfluoropolyethers, such as perfluoro-4,7,10-trioxa-5-methyleicosane, are useful as vapor phase soldering fluids and convection cooling liquids.

Novel perfluoropolyethers

Novel perfluoropolyethers, such as perfluorodipentaerythritol hexaethyl ether, and their intermediates exhibit excellent chemical and thermal stability and are useful as vapor phase soldering fluids and convection cooling liquids.

12222tetrafluoroethyll fluoromethilether and its preparation

Novel perfluorinated polyethers and process for their preparation

Perfluorinated polyethers having the formula R.sub.f O--(CF.sub.2 CF.sub.2 O).sub.n --R'.sub.f wherein n is and integer of 1-11 and each of R f and R' f is a perfluorinated C 1 -C 5 -alkyl radical, dimers of such polyethers and carbon to carbon intramolecularly coupled cyclic derivatives of such polyethers are produced by direct fluorination of the polyethers in an inert solvent. Compositions of the perfluorinated polyethers and their derivatives are useful as functional fluids.

Process for manufacturing oxygenated fluorinated organic compounds

New fluorinated polyethers obtained from perfluoroolefin epoxides and their preparation process

Poly-halogenated ethers inhalation anaesthetics - which are potent ,safe, and non-flammable

Inhalation anaesthetic compsn. contains (a) a life-maintaining amount of oxygen and (b) a cpd. CF2ClOCF2-CHFBr (Ia) or CHF2OCF2cfbrCl (Ib) in an amount suitable for causing anaesthesia. (Ia) and (Ib) are prepd. by chlorinating CH3OCF2CHFBr to give CCl3OCF2CHFBr or CHCl2OCF2CFClBr and fluorinating this to give (Ia) or (Ib). (Ia, Ib) have excellent anaesthetic potency, are non-flammable, and are stable to sodium carbonate. They ensure good muscle-relaxation, and permit the degree of anaesthesia to be readily controlled.

Process for the purification of alpha-methoxy-alpha.alpha-difluoro-beta.beta-dichloro-ethane

Perfluoroolefin epoxy polymers

Patent FR2310747B1

NEW HALOGENOCYCLOPROPYLHALOGENOMETHYLETHERS USEFUL AS ANESTHESICS AND THEIR PREPARATION PROCESS

PROCESS FOR PREPARING PERFLUORATED ETHERS

2-chloro-1,2,2-trifluoroethyl difluoromethyl ether

ABSTRACT OF THE DISCLOSURE The compound 2-chloro-1,2,2-trifluoroethyl difluoromethyl ether, processes for its manufacture, compositions containing it and its use as an inhalation anaesthetic.

Methods of making fluorinated ethers, fluorinated ethers, and uses thereof

플루오르화 에테르의 제조 방법은, 극성 비양성자성 용매 중에서 화학식 X-R f 1 CH 2 OH로 나타내어지는 플루오르화 알코올 및 화학식 R f 2 CH 2 OS(=O) 2 R f 3 으로 나타내어지는 플루오르화 설포네이트 에스테르, 및 염기를 조합하는 단계; 및 화학식 Y-Rf 1 CF 2 OCF 2 Rf 2 -Y로 나타내어지는 플루오르화 에테르를 얻는 단계를 포함한다. R f 1 은 1 내지 10개의 탄소 원자를 갖는 퍼플루오르화 C 1 -C 10 알킬렌 기 및 부분 플루오르화 C 1 -C 10 알킬렌 기, 및 카테나형 헤테로원자(들)를 갖는 그 유도체로부터 선택된다. X는 H, F 또는 HOCH 2 - 기를 나타낸다. R f 2 는 퍼플루오르화 C 1 -C 10 알킬 기 및 부분 플루오르화 C 1 -C 10 알킬 기, 및 카테나형 헤테로원자(들)를 갖는 그 유도체로부터 선택된다. R f 3 은 C 1 -C 4 알킬 기이다. Y는 H, F 또는 R f 2 CH 2 OCH 2 - 기를 나타낸다. 대칭 플루오르화 에테르를 제조하는 데 유용한 변형된 방법이 또한 개시된다. 본 발명은 또한 상기 방법에 따라 제조할 수 있는 플루오르화 에테르를 제공한다. 다양한 응용으로의 플루오르화 에테르의 용도가 또한 개시된다. The process for preparing the fluorinated ether comprises reacting a fluorinated alcohol represented by the formula XR f 1 CH 2 OH and a fluorinated sulfonate represented by the formula R f 2 CH 2 OS (= O) 2 R f 3 in a polar aprotic solvent An ester, and a base; And a fluorinated ether represented by the formula Y-Rf 1 CF 2 OCF 2 Rf 2 -Y. R f 1 is selected from perfluorinated C 1 -C 10 alkylene groups having 1 to 10 carbon atoms and partially fluorinated C 1 -C 10 alkylene groups and derivatives thereof having catenary heteroatom (s) do. X represents H, F or HOCH 2 - group. R f 2 is selected from perfluorinated C 1 -C 10 alkyl groups and partially fluorinated C 1 -C 10 alkyl groups, and derivatives thereof having catenary heteroatom (s). R f 3 is a C 1 -C 4 alkyl group. Y represents H, F or R f 2 CH 2 OCH 2 - group. A modified process useful for preparing symmetrical fluorinated ethers is also disclosed. The present invention also provides a fluorinated ether which can be prepared according to the process. The use of fluorinated ethers in a variety of applications is also disclosed.

Process for the manufacture of dichloralkyl ethers

MONOETHERS OF DICYCLOPENTADIENE-DERIVED POLYOLS AND THEIR PREPARATION

Procédé de préparation de mono-éthers par addition entre un polyol et le dicyclopentadiène, avec un rapport molaire polyol/dicyclopentadiène de 1 : 4 à 2 :1, en présence d'un catalyseur acide, ce mono-éther répondant à la formule : Process for the preparation of monoethers by addition between a polyol and dicyclopentadiene, with a polyol / dicyclopentadiene molar ratio of 1: 4 to 2: 1, in the presence of an acid catalyst, this mono-ether corresponding to the formula:

New fluorinated compounds and their preparation process.

Method for fluorode carboxylation

The present invention is directed to a method for replacing a carboxylic acid group with a fluorine group in a halogenated aliphatic carboxylic acid compound having the formula, R-COOH, to prepare a fluorinated product having the formula, R-F, wherein R is a halogenated aliphatic group including straight- and branched-chain aliphatic groups selected from the group consisting of halogenated aliphatic and halogenated alkoxy-substituted aliphatic groups, wherein the method comprises the steps of (a) reacting the halogenated aliphatic carboxylic acid compound with bromine trifluoride, and (b) recovering the fluorinated product.

Process for the preparation of alkoxy-ethoxy-ethyl chlorides

Method for producing difluoromethylmethyl ether

M 2 CO 3 (M은 알카리 금속)의 구조식을 갖는 염기의 존재 하에서 클로로디플루오로메탄(CHF 2 Cl)과 메탄올을 반응시켜 디플루오로메틸메틸에테르(CF 2 HOCH 3 )를 제조하는 방법을 제공한다.

Process for chlorinating dimethyl ether

Cyclopropane esters

Esters of cyclopropyl substituted carboxylic acids, syntheses thereof, compositions thereof, and use for the control of mites and ticks.

Preparation of alkoxy halides

ABSTRACT OF THE DISCLOSURE Preparation of alkoxy halides Alkyl, aryl or alkylaryl alkoxy halides are prepared by reacting the corresponding alkoxy alcohol with a halogenating agent, e.g. thionyl chloride, in the presence of a quaternary ammonium compound as catalyst. In addition to being faster, the catalysed reaction results in an increased yield of desired product and a decrease in the tendency of the polyoxyalkylene chain to cleave.

Process for preparing perfluorinated ethers

PROCESS FOR PREPARING PERFLUORINATED ETHERS Abstract of the Disclosure: Perfluorinated ethers containing carboxylic acid fluoride groups and optionally units derived from hexafluoropropene epoxide or tetrafluoroethylene epoxide are reacted with fluorine at temperatures of from 50 to 350°C in the presence of metallic catalysts. During the reaction carbonyl difluoride is splitt off and an ether is obtained in high yield which is free of carboxylic acid fluoride groups. Metallic silver is well suited as catalyst.

Process for the production of bis(fluoromethyl)ether and difluoromethane

A process for the production of bis(fluoromethyl)ether by contacting formaldehyde with hydrogen fluoride in a reaction/distillation vessel. The reaction/distillation vessel is preferably a reaction/distillation column through which formaldehyde and hydrogen fluoride preferably flow in counter current. The bis(fluoromethyl)ether may be converted to difluoromethane, preferably by heating the bis(fluoromethyl)ether to elevated temperature in the presence of a metal, metal oxide, metal fluoride or metal oxyfluoride catalyst.

Method of producing fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether

A novel process for preparing fluoromethyl 1,1,1,1,3,3,3 hexafluoroisopropyl eth er, which comprises bringing a polyether represented by the following general formula (1): R1 O(CH2 O)n R2 into contact with hydrogen fluoride and a medium comprising a reaction accelerator (wherein R1 and R2 are each independently hydrogen, C1-C10 alkyl or haloalkyl (w herein the halogen is fluorine, chlorine or bromine); and n is an integer of 1 to 10, with the proviso that both R1 and R2 do not repr esent hydrogen at the same time).

FLUORINATED TELOGENES WITH CCL3 TERMINATION, THEIR PREPARATION AND BISEQUENCY COTELOMERS DERIVATIVE

Process for the preparation of beta-halogen ethers

USE OF PERFLUOROBROMOALKYL ETHERS AS X-RAY CONTRAST AGENTS

Preparation of compounds containing CF3O groups

Gegenstand der vorliegenden Erfindung ist ein Verfahren zur Herstellung von CF3O-Gruppen enthaltenden Verbindungen unter Verwendung von Verbindungen, enthaltend mindestens eine Gruppe Y, worin Y = -Hal, -OSO2(CF2)zF, -OSO2CzH2z+1(z =1-10), -OSO2F, -OSO2Cl, -OC(O)CF3- oder -OSO2Ar ist, ein Verfahren zur Herstellung von CF3O-Gruppen enthaltenden Verbindungen unter Verwendung von KOCF3 und/oder RbOCF3 und neue CF3O-Gruppen enthaltenden Verbindungen und deren Verwendung. The present invention relates to a process for the preparation of compounds containing CF3O groups using compounds containing at least one Y group, in which Y = -Hal, -OSO2 (CF2) zF, -OSO2CzH2z + 1 (z = 1-10) , -OSO2F, -OSO2Cl, -OC (O) CF3- or -OSO2Ar, is a process for producing CF3O group-containing compounds using KOCF3 and / or RbOCF3 and novel compounds containing CF3O groups and their use.

Process for preparing fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether

A novel process for preparing fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether, which comprises bringing a polyether represented by the following general formula (1): R1O(CH2O)nR2 into contact with hydrogen fluoride and a medium comprising a reaction accelerator (wherein R?1 and R2¿ are each independently hydrogen, C¿1?-C10 alkyl or haloalkyl (wherein the halogen is fluorine, chlorine or bromine); and n is an integer of 1 to 10, with the proviso that both R?1 and R2¿ do not represent hydrogen at the same time).

SPHERICAL PERFLUORINE

Fluorqvinyl ethers

Method of making halogenated ethers

Process for preparing perfluorinated ethers

Abstract of the Disclosure: Process for preparing perfluorinated ethers by exposing perfluorocarbonyl compounds of the formula

Sulfinate-initiated addition of perfluorinated iodides to olefins

Chlorofluoroether compositions and preparation thereof

α-BROMO-ω-HALOGEN PERFLUOROPOLYETHERS AS A BASIS OF GAS-TRANSPORT COMPOSITIONS OF MEDICAL-BIOLOGICAL PURPOSE

Настоящее изобретение относится к соединению общей формулы где X=CF 3 , Y=Вr, n=1, 2, 3; X=Y=Br, n=2; X=Br, Y=Cl, n=1, которое может быть использовано в качестве основы газотранспортных композиций медико-биологического назначения. 1 з.п. ф-лы, 14 пр. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 707 081 C1 (51) МПК C07C 43/12 (2006.01) A61K 31/08 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК C07C 43/12 (2019.08); A61K 31/08 (2019.08) (24) Дата начала отсчета срока действия патента: 29.03.2019 Дата регистрации: 22.11.2019 Приоритет(ы): (22) Дата подачи заявки: 29.03.2019 (45) Опубликовано: 22.11.2019 Бюл. № 33 Адрес для переписки: 119991, Москва, В-334, ГСП-1, ул. Вавилова, 28, ИНЭОС РАН, отдел интеллектуальной собственности (73) Патентообладатель(и): Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) (RU), Федеральное государственное бюджетное учреждение науки Институт теоретической и экспериментальной биофизики Российской академии наук (ИТЭБ РАН) (RU) C 1 (56) Список документов, цитированных в отчете о поиске: Hung, Ming-H. et al. Synthesis of Perfluorovinyl Ether Monomers. Journal of Organic Chemistry, 1994, 59(15), 4332-4335. Database CA [online], RN 1262415-94-0, Entered STN: 09 Feb 2011. RU 2497801 C1, 10.11.2013. US 4640833 A1, 03.02.1987. (54) α-БРОМ-ω-ГАЛОГЕНПЕРФТОРПОЛИЭФИРЫ В КАЧЕСТВЕ ОСНОВЫ ГАЗОТРАНСПОРТНЫХ КОМПОЗИЦИЙ МЕДИКО-БИОЛОГИЧЕСКОГО НАЗНАЧЕНИЯ (57) Реферат: Настоящее изобретение относится к X=CF3, Y=Вr, n=1, 2, 3; X=Y=Br, n=2; X=Br, Y=Cl, соединению общей формулы n=1, которое может быть использовано в качестве R U где Стр.: 1 основы газотранспортных композиций медикобиологического назначения. 1 з.п. ф-лы, 14 пр. C 1 2 7 0 7 0 8 1 (72) Автор(ы): Маевский Евгений Ильич (RU), Игумнов Сергей Михайлович (RU), Стерлин Сергей Рафаилович (RU), Тютюнов Андрей Александрович (RU) 2 7 0 7 0 8 1 2019109182 ...

Process for preparing chf2ochfcf3 and chf2ochclcf3 and novel intermediate compounds employed thereby

Methods of making fluorinated ethers, fluorinated ethers, and uses thereof

A method of making a fluorinated ether includes combining, in a polar aprotic solvent: a fluorinated alcohol represented by the formula X—R f 1 CH 2 OH, and a fluorinated sulfonate ester represented by the formula R f 2 CH 2 OS(═O) 2 R f 3 , and base; and obtaining a fluorinated ether represented by the formula Y—R f 1 CH 2 OCH 2 R f 2 —Y. R f 1 is selected from perfluorinated C 1 -C 10 alkylene groups having from 1 to 10 carbon atoms and partially fluorinated C 1 -C 10 alkylene groups, and derivatives thereof having catenated heteroatom(s). X represents H, F, or an HOCH 2 — group. R f 2 is selected from perfluorinated C 1 -C 10 alkyl groups and partially fluorinated C 1 -C 10 alkyl groups, and derivatives thereof having catenated heteroatom(s). R f 3 is a C 1 -C 4 alkyl group. Y represents H, F, or an R f 2 CH 2 OCH 2 — group. A variant method, useful for preparing symmetric fluorinated ethers, is also disclosed. The present disclosure also provides fluorinated ethers preparable according to the methods. Use of fluorinated ethers in various applications is also disclosed.

Preparation of chlorotrifluoroethylene telomers with fluoroxytrifluoromethane and bisfluoroxydifluoro methane

Telomers of formula CF3O - (CFCl - CF2)n - X where n is 1-10 and X is F or OCF3, are formed by reacting chlorotrifluoroethylene with fluoroxytrifluoromethane or bisfluoroxydifluoromethane. The telomerization reaction is conducted either in liquid chlorotrifluoroethylene without a solvent or in solution. The telomers thus formed can optionally befluorinated (e.g. with ClF3) to improve their stability by replacing some or all of the chlorine by fluorine.

PROCESS FOR PREPARING MONOETHERS FROM DICYCLOPEN TADIENE.

Fluorinated ethers as inhalation convulsants

THIS APPLICATION RELATES TO THE USE OF CERTAIN FLUORINATED ETHERS AS INHALATION CONVULSANTS AND TO CERTAIN OF THESE ETHERS WHICH ARE NOVEL PER SE.

Halocyclopropyl halomethyl ethers

ABSTRACT OF THE DISCLOSURE The following halocyclopropyl halomethyl ethers have been synthesized and found to posses utility as general inhalation anesthetics: 1-chloro-2-chlorofluoromethoxy-1,2,3,3-tetrafluorocyclopropane, 1-chloro-2-difluoro-methoxy-1,2,3,3-tetrafluorocyclopropane, 1-bromo-2-chloro-fluoromethoxy-1,2, 3,3-tetrafluorocyclopropane and 1-bromo-2-difluoromethoxy-1,2,3,3-tetrafluoro-cyclopropane.

Fluorinated telogens possessing a CCl`` end group, the preparation thereof and double-sequence cotelomers derived therefrom

Synthesis of 2-¬1-(2,5-dimethylphenyl) ethylsulfonyl|pyridine-1-oxide herbicide and intermediates therefor

Abstract Hydrogen chloride is passed into p-xylene actaldehyde to form bis-1-chloroethyl ether; the latter is converted to 2-(1-chloro-ethyl)-1,4-dimethlbenzend by the action of sulfuric acid and hy-drogen chloride. Alkali metal hydrogen sulfide in aqueous methanol or ethanol converts the 2-(1-chlorethyl)-1,4-dimethylbenzene to alpha,2,5-trimethlbenzenemethanethiol; the sodium salt of the latter reacted with 2-chloropyridine-1-oxide yields 2-[1-(2,5 dimethylphenyl)ethylthio]pyridine-1-oxide yields 2-[1-2,5-with hydrogen peroxide and alkali metal tungstate or tungstic acid to form 2-[1-2,5-dimethylphenyl)ethylsulfonl]pyridine-1-oxide.

Inhalation anesthetic or analgesic method and composition

THE PRESENT INVENTION RELATES TO THE NOVEL COMPOUND 1,1,2,2-TETRAFLUOROETHYL FLUOROMETHYL ETHER (CHF2CF2OCH2F) THE COMPOUND IS PREPARED THROUGH SELECTIVE STEPWISE CHLORINATION AND FLUORINATION OF 1,1,2,2-TETRAFLUOROETHYL METHYL ETHER. THE COMPOUND IS USEFUL AS AN ANESTHETIC AND AS A SOLVENT AND DISPERSANT FOR FLUORINATED MATERIALS. THE COMPOUND HAS THE UNUSUAL PROPERTY OF CAUSING AN ANALGESIC EFFECT ON MAMMALS AT SUBANESTHETIC CONCENTRATIONS.

Biscfluoromethy ether, its producing process and use for production of difluoromethane

包含二(氟甲基)醚和比它摩尔数少的水的组合物，此组合物的制备方法包括将甲醛和HF接触并从二(氟甲基)醚中分离至少一些副产物水，及使用此组合物制备二氟甲烷。

Preparation of bis-chloromethyl ether

Method for the preparation of sevoflurane

본 발명은 (CF 3 ) 2 CHOCH 2 Cl, 포타슘 플루오라이드, 물 및 상전이촉매의 혼합물을 제공하고, 상기 혼합물을 반응시켜서 (CF 3 ) 2 CHOCH 2 F을 형성하는 (CF 3 ) 2 CHOCH 2 F(세보플루란)의 제조방법을 나타낸다. The present invention provides a mixture of (CF 3 ) 2 CHOCH 2 Cl, potassium fluoride, water and a phase transfer catalyst, and reacting the mixture to form (CF 3 ) 2 CHOCH 2 F (CF 3 ) 2 CHOCH 2 F The manufacturing method of (Sevoflurane) is shown.

Chlorofluoroether compositions and preparation thereof

Normally liquid chlorofluoroether compositions consisting or consisting essentially of one or a selected mixture of perhalogenated chlorofluoroether compounds are provided by direct fluorination of the corresponding chloroether or chlorofluoroether precursors. The compositions are useful, for example, as heat transfer agents, blood substitutes, and solvents.

Novel halogenated ether useful as an inhalation anaesthetic

1,141,099. Halogenated ether. ALLIED CHEMICAL CORP. 9 Jan., 1968 [10 Jan., 1967], No. 1327/68. Heading C2C. Novel 1 - chloro - 1,1,3,3,3 - pentafluoro - 2 - propyl methyl ether is produced by the reaction of 1 - chloro - 1,1,3,3,3 - pentafluoro propan - 2-ol with dimethyl sulphate. 1 - Chloro - 1,1,3,3,3 - pentafluoro -propan - 2 - ol is prepared from NaBH 4 , diethylene glycol dimethyl ether and gaseous pentafluoromonochloroacetone, to which reaction mixture was added ice water and concentrated hydrochloric acid.

Process for preparing perhaloethers from perhaloolefins and new perhaloethers thereby obtained

The invention relates to a process for preparing perhaloethers from perhaloolefins and to a few "per se" new classes of perhaloethers thereby obtained. The process consists in reacting a perhalomonoolefin with a fluoroxy compound R x --OF (wherein R x represents a perhalogenated alkyl radical) at a temperature not exceeding 20° C. in a liquid reaction medium and in the presence of inert gases.

Compositions and methods for producing anesthesia

The present invention relates to anesthetic compositions containing 1,1,2-trifluoro-2-chloro-2-bromoethyl difluoromethyl ether and 1,1,2-trifluoro-2-bromoethyl difluorochloromethyl ether, and to the method of anesthetizing warm blooded air breathing mammals by administering an effective amount of each anesthetic composition.

Fluoride alkyl glycerin derivatives, preparation method therefor and use thereof

본 발명은 분자 구조 내 관능기 및 탄소수가 조절되어 우수한 계면활성제로서 사용 가능한 불화알킬글리세린 유도체, 이의 제조방법 및 계면활성제 용도를 개시한다. The present invention discloses a fluorinated alkylglycerin derivative that can be used as an excellent surfactant by controlling the number of functional groups and carbon atoms in the molecular structure, a preparation method thereof, and use of a surfactant.

Inhalant anesthetic compositions and method

The novel compounds 2,2-difluoroethyl difluoromethyl ether and its 1-chloro derivative having the formula CHF2CHCl-O-CHF2 are disclosed. The latter compound can be prepared through chlorination of 2,2-difluoroethyl difluoromethyl ether which in turn can be made by reaction of 2,2-difluoroethanol and difluorochloromethane in the presence of aqueous sodium hydroxide. The novel compounds are useful as inhalation anesthetics and as solvents and dispersants for fluorinated materials.

APPLICATION OF PERFLUORO BROMALCULATORS AS A RONTGEN CONTRACTING AGENT

Process for obtaining tetrahydro-1, 4-oxazines substituted in 2, 4 and in 2, 2, 4

TELOGENES FLUORES WITH TERMINATION CCL3, THEIR PREPARATION AND COTELOMERES BISQUENCES BY DERIVING

For the Contracting States : BE, CH, DE, GB, LT, LI, LU, NL, SE 1. Fluorinated telogens possessing a CCl3 end group, characterized in that they correspond to the general formula : Rf-Q-CII3 in which Rf denotes a linear or branched perfluoroalkyl radical containing from 2 to 20 carbon atoms and Q denotes a linkage group chosen from those of formulae : -(CH2 )r -OCO-(CH2 )S - see diagramm : EP0188952,P23,F1 -(CH2 )r' -COO-(CH2 )s' - see diagramm : EP0188952,P23,F2 or Rf and Q denote together a group of formula : see diagramm : EP0188952,P24,F3 in which : r and s' are integers ranging from 1 to 12, r' and s are integers ranging from 0 to 12, X denotes a hydrogen, chlorine or bromine atom, X denotes a -CH2 -, -CH2 -CCl2 -, -CH2 -CCl2 -CH2 - or -CH2 CCl2 -CF2 - bridge, R denotes a hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms, Y denotes an oxygen or sulphur atom, Z denotes a -CH2 -, -CH2 -C6 H4 - or -COO-(CH2 )t - bridge, t being an integer ranging from 0 to 9, R' denotes a hydrogen atom or a methyl group, W' denotes a direct bond or a -CCl2 -, -CCl2 -CH2 - or -CCl2 -CF2 - bridge, and u is a number ranging from 2 to 100. For the Contracting State : AT 1. Process for the preparation of fluorinated telogens of general formula : Rf-Q-CCl3 in which Rf denotes a linear or branched perfluoroalkyl radical containing from 2 to 20 carbon atoms and Q denotes a linkage group chosen from those of formulae : -(CH2 )r -OCO-(CH2 )S - see diagramm : EP0188952,P25,F1 -(CH2 )r' -COO-(CH2 )s' - see diagramm : EP0188952,P25,F2 or Rf and Q denote together a group of formula : see diagramm : EP0188952,P26,F3 in which : r and s' are integers ranging from 1 to 12, r' and s are integers ranging from 0 to 12, X denotes a hydrogen, chlorine or bromine atom, W denotes a -CH2 -, -CH2 -CCl2 -, -CH2 -CCl2 -CH2 - or -CH2 CCl2 -CF2 - bridge, R denotes a hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms, Y denotes an oxygen ...

Process for the purification of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane)

A process for purifying crude fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane). The crude sevoflurane is repeatedly washed with water under conditions and for a time sufficient to reduce the level of 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) to no more than 200 ppm or no more than 100 ppm.

Preparation of isoflurane by reaction of 2,2,2-trifluoroethyl difluoromethyl ether and chlorine in added water, at low temperatures and/or at higher conversions

A process for preparing isoflurane (1-chloro-2,2,2-trifluoroethyl difluoromethyl ether) by reacting PFE (2,2,2-trifluoroethyl difluoromethyl ether) with chlorine in the presence of ultraviolet light and added water, at a low temperature and/or at a high conversion.

Improvements to the process for preparing chloromethyl-methyl ether

Patent TW218004B

Production of surface-active ether sulfonates

Anesthetically active fluorinated methyl ethers

Production of hyrofluorocarbons

A process for the production of a hydro(halo)fluorocarbon which comprises heating an α-fluoroether in the vapor phase at elevated temperature. α-fluoroethers are obtained by reacting a non-enolisable aldehyde with hydrogen fluoride to form an intermediate and reacting the intermediate with an alcohol or a halogenating agent. Novel α-fluoroethers are also provided.

Preparation of isoflurane by reaction of 2,2,2-trifluoroethyl difluoromethyl ether and chlorine in added water, at low temperatures and/or at higher conversions

A process for preparing isoflurane (1-chloro-2,2,2-trifluoroethyl difluoromethyl ether) by reacting PFE (2,2,2-trifluoroethyl difluoromethyl ether) with chlorine in the presence of ultraviolet light and added water, at a low temperature and/or at a high conversion.

PROCESS FOR THE PREPARATION OF THE NEW 2-CHLORO -1,2,2- TRIFLUORATHYL - DIFLUOROMETHYLATHER

Process for the uniform coating of cylinders, in particular printing form cylinders, with light-sensitive materials

Alpha omega bis (fluoroperhaloisopropoxy)- - perfluoroalkanes

Process for producing perhaloether from perhaloolefin and novel perhaloether obtained thereby

Preparation of isoflurane by reaction of 2,2,2-trifluoroethyl difluoromethyl ether and chlorine in added water, at low temperatures and/or at higher conversions

A process for preparing isoflurane (1-chloro-2,2,2-trifluoroethyl difluoromethyl ether) by reacting PFE (2,2,2-trifluoroethyl difluoromethyl ether) with chlorine in the presence of ultraviolet light and added water, at a low temperature and/or at a high conversion.

Process for synthesizing hydroxymethyl-dihalo-dialkylphenol

A hydroxymethyl-dihalo-dialkylphenol is synthesized by contacting a halomethyl-dihalo-dialkylphenol with a substantial excess of water in a water-miscible organic solvent at a temperature of less than 55 DEG C. The obtained product can be used to form epoxy resins useful as electrical components.

Hydrolysis of halo- and alkyl-substituted phenols

A hydroxymethyl-dihalo-dialkylphenol is synthesized by contacting a halomethyl-dihalo-dialkylphenol with a substantial excess of water in a water-miscible organic solvent at a temperature of less than 55 DEG C. The obtained product can be used to form epoxy resins useful as electrical components.

FOR X-RAY RADIATION AND IMPERMEABLE MEDIUM.

Process for preparing fluorohalogenethers

Process for the purification of fluromethyl 1,1,1,3,3,3,-hexafluoroisopropyl ether (sevoflurane)

A process for purifying crude fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane). The crude sevoflurane is repeatedly washed with water under conditions and for a time sufficient to reduce the level of 1,1, 1,3,3, 3-hexafluoroisopropanol (HFIP) to no more than 200 ppm or no more than 100 ppm.

Perfluoropolyether compound

The present compound is a novel perfluoropolyether represented by the following general formula: <IMAGE> wherein m is an integer of 1 to 3 and n is an integer of 2 to 6. This compound is quite useful as an inert liquid used as a heat transfer mediums in the filed of electronic materials.

Polyfluoroethers

A polyether of the formula: wherein m is a number of 2 to 5, n is a number of 1 to 5, R f ¹ is a perfluoroalkyl group having 7 to 11 carbon atoms, and R f ² is a perfluoroalkyl group having 3 to 11 carbon atoms, which has a high boiling point and is chemically and thermally stable.

Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of making and using them

This invention relates to compositions comprising highly fluorinated, chloro-substituted, non-cyclic organic compounds having 7 to 9 carbon atoms and to processes of using them. More particularly, this invention relates to emulsions comprising those highly fluorinated, chloro-substituted organic compounds in a sufficiently high concentration to be effective in the desired level of oxygen transport, which emulsions are capable of sterilization; have long term stability, persist for sufficiently long times in the bloodstream to deliver useful quantities of oxygen, yet be eliminated rapidly enough from the body to avoid toxicity arid retention in body parts and organs. This invention also relates to emulsions comprising non-cyclic perfluorochloroethers having 7 to 10 carbon atoms, preferably 7 to 9 carbon atoms, especially perfluoro-bis-chlorobutyl ether. These novel emulsions have various medical and oxygen transport applications, such as "artificial blood" and preserving organs.

Process for the preparation of 1, 4-dichlorobutane and 4, 4'-dichlorodibutyl ether

ALKANE HALOGEN ETHER, ITS OBTAINING AND ANESTHESIC COMPOSITION CONTAINING IT

Halogen-containing ethers

Abstract of the disclosure Halogen-containing ethers The invention relates to compounds of the formula (I)