19-10-2017 дата публикации
Номер: US20170298092A1
Принадлежит:
CLARCOR Inc.
A functionalized fine fiber is provided. In an embodiment, the functionalized fine fiber is usable in chromatography. The functionalized fine fiber includes a matrix of fine fiber. The fine fibers preferably have an average diameter of less than 2 micron, and each fine fiber preferably has a length of at least 1 millimeter. The fine fibers carry and immobilize functional molecules. 1. A functionalized fine fiber , usable in chromatography , comprising:a matrix of fine fiber, the fine fiber having an average diameter of less than 2 micron, each fine fiber having a length of at least 1 millimeter; andfunctional molecules carried and immobilized by the fine fiber.2. The functionalized fine fiber of claim 1 , wherein the functional molecules are ligands.3. The functionalized fine fiber of claim 2 , wherein the ligands are selected from the group consisting of antibodies specific to target proteins.4. The functionalized fine fiber of claim 1 , further wherein the fine fiber is formed of at least one polymer selected from the group consisting of polytetrafluoroethylene claim 1 , polyvinylidene fluoride claim 1 , other fluoropolymers claim 1 , polyamide claim 1 , polyester claim 1 , cellulose claim 1 , polysulfone claim 1 , polyethylene claim 1 , polypropylene claim 1 , polystyrene claim 1 , and poly(4-vinylpyridine).5. The functionalized fine fiber of claim 1 , wherein the functional molecules comprise at least one metal ion claim 1 , the metal of the at least one metal ion selected from the group consisting of: cobalt claim 1 , nickel claim 1 , copper claim 1 , iron claim 1 , zinc claim 1 , and gallium.6. The functionalized fine fiber of claim 1 , wherein the functional molecules are hydrophobic groups.7. The functionalized fine fiber of claim 6 , wherein the hydrophobic groups include one or more of a phenyl group claim 6 , an octyl group claim 6 , and a butyl group.8. The functionalized fine fiber of claim 1 , wherein the fine fiber is contained in a fibrous web ...
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