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Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-like Proteins

Номер патента: US20110256064A1
Опубликовано: 20-10-2011
Автор(ы): Andreas Muhs, Cotinica Hamel, Heiko Kroth, NAMPALLY Sreenivasachary, Pascal Benderitter, Wolfgang Froestl
Принадлежит: AC IMMUNE SA
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Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated diseases

Номер патента: US09388149B2. Автор: Jérome Aubert,Branislav Musicki,Laurence Clary,Patricia Rossio,Marlene Schuppli-Nollet,Jean-Guy BOITEAUX. Владелец: Galderma Research and Development SNC. Дата публикации: 2016-07-12.

Novel compounds for use in the treatment of Clostridium Difficile and associated diseases

Номер патента: GB2482501A. Автор: James Edward KITULAGODA,Colin Richard Dorgan,Francis Xavier Wilson,Richard Vickers,Stephen Paul Wren,Lauren Jayne Sudlow. Владелец: Summit Corp Plc. Дата публикации: 2012-02-08.

The use of compounds such as pyridoxal derivatives for the treatment of diabetes or diseases associated with the metabolic syndrome

Номер патента: WO2009005469A3. Автор: Olov Sterner,David Erlinge,Albert S Salehi,Stefan Amisten,Sandra Meidute-Abaravecien,Johan Wingstrand. Владелец: Sandra Meidute-Abaravecien. Дата публикации: 2009-02-26.

Compounds and methods for the diagnosis and treatment of amyloid associated diseases

Номер патента: US8741883B2. Автор: Jerry Yang,Petra Inbar. Владелец: University of California San Diego UCSD. Дата публикации: 2014-06-03.

Compounds and methods for the diagnosis and treatment of amyloid associated diseases

Номер патента: US20100178282A1. Автор: Jerry Yang,Petra Inbar. Владелец: UNIVERSITY OF CALIFORNIA. Дата публикации: 2010-07-15.

Compounds and methods for the prevention and treatment of tumor metastasis and tumorigenesis

Номер патента: US09663521B2. Автор: Wei Zheng,Sui Huang,Juan Jose Marugan,Samarjit Patnaik,Kevin Frankowski,Frank J. Schoenen,John Norton,Noel Terrence Southall,Steven Titus. Владелец: US Department of Health and Human Services. Дата публикации: 2017-05-30.

Compounds for use in the treatment of hyperproliferative disorders

Номер патента: US20240208998A1. Автор: Xavier BARRIL ALONSO,Josep TABERNERO CATURLA,Carlos GALDEANO CANTADOR,Héctor GARCíA PALMER,Diego MUÑOZ-TORRERO LÓPEZ-IBARRA,Isabel PUIG BORREIL,Sergio RUIZ CARMONA. Владелец: Fundacio Privada Institut dInvestigacio Oncologica Vall dHebron VHIO. Дата публикации: 2024-06-27.

Compositions and Methods for the Prevention and Treatment of Hearing Loss

Номер патента: US20230330097A1. Автор: Jian Zuo,Jeff North. Владелец: Ting Therapeutics LLC. Дата публикации: 2023-10-19.

Compositions and methods for the prevention and treatment of hearing loss

Номер патента: EP4214193A1. Автор: Jian Zuo,Marisa Laura Zallocchi,Santanu Hati,Jeff North. Владелец: Ting Therapeutics LLC. Дата публикации: 2023-07-26.

Compositions and methods for the prevention and treatment of hearing loss

Номер патента: WO2022060811A1. Автор: Jian Zuo,Marisa Laura Zallocchi,Santanu Hati,Jeff North. Владелец: Ting Therapeutics LLC. Дата публикации: 2022-03-24.

Compositions and methods for the prevention and treatment of hearing loss

Номер патента: US12070465B2. Автор: Jian Zuo,Marisa Laura Zallocchi,Santanu Hati,Jeff North. Владелец: Ting Therapeutics LLC. Дата публикации: 2024-08-27.

4{4-[3-(4-chloro-3-trifluoromethylphenyl)-ureido]-3-fluorophenoxy}-pyridine-2-carboxylic acid methylamide and metabolites for the treatment and prevention of diseases and conditions

Номер патента: NZ544920A. Автор: Stephen Boyer,Jacques Dumas,Bernd Riedl,Scott Wilhelm. Владелец: Bayer HealthCare LLC. Дата публикации: 2009-11-27.

Compounds for use in the treatment of mycobacterial infections

Номер патента: US09920042B2. Автор: Benoit Deprez,Nicolas Willand,Alain Baulard,Priscille Brodin,Vincent Villeret,Baptiste Villemagne,Olivier Sperando. Владелец: Universite Lille 2 Droit et Sante. Дата публикации: 2018-03-20.

Estrogen receptor beta ligands for the prevention and treatment of multiple sclerosis (ms) and other demyelinating, inflammatory and neurodegenerative diseases

Номер патента: WO2019226936A1. Автор: Sung Hoon Kim,John A. Katzenellenbogen,Benita KATZENELLENBOGEN,Seema K. TIWARI-WOODRUFF. Владелец: The Board of Trustees of the University of Illinois. Дата публикации: 2019-11-28.

Estrogen receptor beta ligands for the prevention and treatment of multiple sclerosis (ms) and other demyelinating, inflammatory and neurodegenerative diseases

Номер патента: US20210230121A1. Автор: Sung Hoon Kim,John A. Katzenellenbogen,Benita KATZENELLENBOGEN,Seema K. TIWARI-WOODRUFF. Владелец: University of Illinois. Дата публикации: 2021-07-29.

Estrogen receptor beta ligands for the prevention and treatment of multiple sclerosis (ms) and other demyelinating, inflammatory and neurodegenerative diseases

Номер патента: EP3796905A1. Автор: Sung Hoon Kim,John A. Katzenellenbogen,Benita KATZENELLENBOGEN,Seema K. TIWARI-WOODRUFF. Владелец: University of Illinois. Дата публикации: 2021-03-31.

Estrogen receptor beta ligands for the prevention and treatment of multiple sclerosis (ms) and other demyelinating, inflammatory and neurodegenerative diseases

Номер патента: US20230357161A1. Автор: Sung Hoon Kim,John A. Katzenellenbogen,Benita KATZENELLENBOGEN,Seema K. TIWARI-WOODRUFF. Владелец: University of Illinois. Дата публикации: 2023-11-09.

Substituted 11-phenyl-dibenzazepine compounds useful for the treatment or prevention of diseases characterized by abnormal cell proliferation

Номер патента: CA2310748C. Автор: Minghua Sun,Jose Halperin,Ying-Duo Gao,Adel M. Moussa,Carlo Brugnara,Emile M. Bellott, Jr.,John J. Clifford,Reem M. Haidar,Eugene W. Kelleher,Yesh P. Sachdeva,Heather N. Taft,Rudolf Fluckiger,Richard John Lombardy,Michael H. Zeldin. Владелец: Nuchem Pharmaceuticals Inc. Дата публикации: 2008-07-22.

Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment or prevention of diseases characterized by abnormal cell proliferation

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Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment or prevention of diseases characterized by abnormal cell proliferation

Номер патента: EP1047411A4. Автор: Minghua Sun,Jose Halperin,Ying-Duo Gao,Adel M Moussa,Carlo Brugnara,Rudolf Fluckiger,Richard John Lombardy,Yesh P Sachdeva,John J Clifford,Reem M Haidar,Eugene W Kelleher,Heather N Taft,Emile M Bellott Jr. Владелец: Nuchem Pharmaceuticals Inc. Дата публикации: 2000-12-06.

Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment or prevention of diseases characterized by abnormal cell proliferation

Номер патента: EP1047411A1. Автор: Minghua Sun,Jose Halperin,Ying-Duo Gao,Adel M. Moussa,Carlo Brugnara,Emile M. Bellott, Jr.,John J. Clifford,Reem M. Haidar,Eugene W. Kelleher,Yesh P. Sachdeva,Heather N. Taft,Rudolf Fluckiger,Richard John Lombardy. Владелец: Nuchem Pharmaceuticals Inc. Дата публикации: 2000-11-02.

Heterocyclic compounds for use in the treatment of cancer

Номер патента: AU2022374050A1. Автор: Robert Heald,Harry Finch,Owen Davis,Martin Stockley,Sam MANN. Владелец: Artios Pharma Ltd. Дата публикации: 2024-05-02.

Heterocyclic compounds for use in the treatment of cancer

Номер патента: WO2023067356A1. Автор: Robert Heald,Harry Finch,Owen Davis,Martin Stockley,Sam MANN. Владелец: Artios Pharma Limited. Дата публикации: 2023-04-27.

Heterocyclic compounds for use in the treatment of cancer

Номер патента: EP4419526A1. Автор: Robert Heald,Harry Finch,Owen Davis,Martin Stockley,Sam MANN. Владелец: Artios Pharma Ltd. Дата публикации: 2024-08-28.

Heterocyclic compounds for use in the treatment of cancer

Номер патента: EP4419527A1. Автор: Robert Heald,Harry Finch,Owen Davis,Martin Stockley,Sam MANN. Владелец: Artios Pharma Ltd. Дата публикации: 2024-08-28.

Oxadiazaspiro compounds for use in the treatment of motoneuron degeneration or in neuroprotection

Номер патента: EP4404933A1. Автор: Jose-Miguel Vela-Hernandez,Manuel Merlos-Roca,Xavier NAVARRO-ACEBES,Mireia HERRANDO-GRABULOSA. Владелец: Esteve Pharmaceuticals SA. Дата публикации: 2024-07-31.

Heterocyclic compounds for use in the treatment of cancer

Номер патента: EP4419525A1. Автор: Johannes Wilhelmus Maria Nissink,Robert Heald,Harry Finch,Owen Davis,Martin Stockley,Sam MANN. Владелец: Artios Pharma Ltd. Дата публикации: 2024-08-28.

Novel compounds and compositions for the inhibition of nampt

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Novel compounds and compositions for the inhibition of nampt

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Imidazo[1,2-a]pyridinyldiacid compounds for cognitive enhancement and for treatment of cognitive disorders and neutrotoxic injury

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2-oxo-thiazole derivatives as A2A inhibitors and compounds for use in the treatment of cancers

Номер патента: US10995101B2. Автор: Stefano Crosignani,Bruno Gomes,Erica Houthuys. Владелец: Iteos Therapeutics SA. Дата публикации: 2021-05-04.

Compound for use in the treatment of neurogenic orthostatic hypotension

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Compound for use in the treatment of neurogenic orthostatic hypotension

Номер патента: MY194181A. Автор: Sharathchandra S Hegde. Владелец: Theravance Biopharma R&D Ip Llc. Дата публикации: 2022-11-17.

Compounds for the prevention and treatment of cardiovascular diseases

Номер патента: CA2676984C. Автор: Henrik Hansen. Владелец: Resverlogix Corp. Дата публикации: 2015-03-17.

Compound for use in the treatment of neurogenic orthostatic hypotension

Номер патента: NZ750392A. Автор: Sharathchandra S Hegde. Владелец: Theravance Biopharma R&D Ip Llc. Дата публикации: 2020-08-28.

Novel disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated diseases

Номер патента: AU2012328198A1. Автор: Jérome Aubert,Branislav Musicki,Laurence Clary,Patricia Rossio,Marlene Schuppli-Nollet,Jean-Guy BOITEAUX. Владелец: Galderma Research and Development SNC. Дата публикации: 2014-04-03.

Lipidic furan, pyrrole, and thiophene compounds for use in the treatment of atrophic vaginitis

Номер патента: US20210106551A1. Автор: Samuel Richard Huber. Владелец: AVOSCIENCE LLC. Дата публикации: 2021-04-15.

Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of disorders related thereto

Номер патента: US20230277505A1. Автор: Hongmei Li,Sonja Strah-Pleynet,Bradley Teegarden,Peter I. Dosa,Honnappa Jayakumar. Владелец: Arena Pharmaceuticals Inc. Дата публикации: 2023-09-07.

Diaryl and arylheteroaryl urea derivatives as modulators of the 5-HT2A serotonin receptor useful for the prophylaxis and treatment of disorders related thereto

Номер патента: US09775829B2. Автор: Hongmei Li,Sonja Strah-Pleynet,Bradley Teegarden,Peter I. Dosa,Honnappa Jayakumar. Владелец: Arena Pharmaceuticals Inc. Дата публикации: 2017-10-03.

Compounds for use in the treatment of filariasis

Номер патента: US20140073688A1. Автор: Alexander Schmitz,Kenneth Michael Pfarr,Andrea Schiefer,Stefan Kehraus,Achim Hoerauf,Gabriele Maria Koenig,Sabine Specht,Till Friedrich Schaeberle. Владелец: Rheinische Friedrich Wilhelms Universitaet Bonn. Дата публикации: 2014-03-13.

Compounds for use in the treatment of filariasis

Номер патента: US20150182498A1. Автор: Alexander Schmitz,Kenneth Michael Pfarr,Andrea Schiefer,Stefan Kehraus,Achim Hoerauf,Gabriele Maria Koenig,Sabine Specht,Till Friedrich Schaeberle. Владелец: Rheinische Friedrich Wilhelms Universitaet Bonn. Дата публикации: 2015-07-02.

Compounds for use in the treatment of hyperproliferative disorders

Номер патента: EP4326262A1. Автор: Xavier BARRIL ALONSO,Josep TABERNERO CATURLA,Carlos GALDEANO CANTADOR,Héctor GARCíA PALMER,Diego MUÑOZ-TORRERO LÓPEZ-IBARRA,Isabel PUIG BORREIL,Sergio RUIZ CARMONA. Владелец: Fundacio Privada Institut dInvestigacio Oncologica Vall dHebron VHIO. Дата публикации: 2024-02-28.

Compounds for use in the treatment of hyperproliferative disorders

Номер патента: CA3216090A1. Автор: Xavier BARRIL ALONSO,Josep TABERNERO CATURLA,Carlos GALDEANO CANTADOR,Héctor GARCíA PALMER,Diego MUÑOZ-TORRERO LÓPEZ-IBARRA,Isabel PUIG BORREIL,Sergio RUIZ CARMONA. Владелец: Fundacio Privada Institut dInvestigacio Oncologica Vall dHebron VHIO. Дата публикации: 2022-10-27.

Compounds for use in the treatment of hyperproliferative disorders

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Compounds for use in the treatment of filariasis

Номер патента: US20150182497A1. Автор: Alexander Schmitz,Kenneth Michael Pfarr,Andrea Schiefer,Stefan Kehraus,Achim Hoerauf,Gabriele Maria Koenig,Sabine Specht,Till Friedrich Schaeberle. Владелец: Rheinische Friedrich Wilhelms Universitaet Bonn. Дата публикации: 2015-07-02.

Compounds for use in the treatment of filariasis

Номер патента: EP2704708A1. Автор: Alexander Schmitz,Achim Hörauf,Kenneth Michael Pfarr,Andrea Schiefer,Stefan Kehraus,Sabine Specht,Gabriele Maria König,Till Friedrich Schäberle. Владелец: Rheinische Friedrich Wilhelms Universitaet Bonn. Дата публикации: 2014-03-12.

Compounds for use in the treatment of filariasis

Номер патента: US9168244B2. Автор: Alexander Schmitz,Kenneth Michael Pfarr,Andrea Schiefer,Stefan Kehraus,Achim Hoerauf,Gabriele Maria Koenig,Sabine Specht,Till Friedrich Schaeberle. Владелец: Rheinische Friedrich Wilhelms Universitaet Bonn. Дата публикации: 2015-10-27.

Compounds for use in the treatment of filariasis

Номер патента: WO2012150340A1. Автор: Alexander Schmitz,Achim Hörauf,Kenneth Michael Pfarr,Andrea Schiefer,Stefan Kehraus,Sabine Specht,Gabriele Maria König,Till Friedrich Schäberle. Владелец: RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT BONN. Дата публикации: 2012-11-08.

Imidazopyridine amides and related compounds for use in the treatment of bacterial infections

Номер патента: CA3234515A1. Автор: José Manuel Bartolomé-Nebreda,María Luz Martín-Martín,Katie Ingrid Eduard Amssoms,Bart Henri Theresia STOOPS,Dirk Antonie LAMPRECHT,Guido Alfons F Verniest. Владелец: Janssen Sciences Ireland ULC. Дата публикации: 2023-05-04.

Compounds and methods for the prevention and treatment of tumor metastasis and tumorigenesis

Номер патента: US20170260192A1. Автор: Wei Zheng,Sui Huang,Juan Jose Marugan,Samarjit Patnaik,Kevin Frankowski,Frank J. Schoenen,John Norton,Noel Terrence Southall,Steven Titus. Владелец: US Department of Health and Human Services. Дата публикации: 2017-09-14.

Compounds and methods for the prevention and treatment of tumor metastasis and tumorigenesis

Номер патента: EP2791142A1. Автор: Wei Zheng,Sui Huang,Juan Jose Marugan,Samarjit Patnaik,Kevin Frankowski,Frank J. Schoenen,Noel Southall,John Norton,Steven Titus. Владелец: US Department of Health and Human Services. Дата публикации: 2014-10-22.

Aryl hydrocarbon receptor ligands and their analogues for the prevention and treatment of inflammatory disorders

Номер патента: US20230357261A1. Автор: Peng Lu,Peter Wipf,David HACKAM,Chhinder P. Sodhi,David Kornfilt. Владелец: JOHNS HOPKINS UNIVERSITY. Дата публикации: 2023-11-09.

Compound for use in the treatment of dry mouth

Номер патента: US20230321085A1. Автор: Michiel Henricus de Vries,Dorien Groenendaal. Владелец: Asahi Pharma Co Ltd. Дата публикации: 2023-10-12.

Oxadiazaspiro compounds for use in the treatment of motoneuron degeneration or in neuroprotection

Номер патента: CA3230908A1. Автор: Jose-Miguel Vela-Hernandez,Manuel Merlos-Roca,Xavier NAVARRO-ACEBES,Mireia HERRANDO-GRABULOSA. Владелец: Esteve Pharmaceuticals SA. Дата публикации: 2023-03-23.

Oxadiazaspiro compounds for use in the treatment of motoneuron degeneration or in neuroprotection

Номер патента: AU2022346825A1. Автор: Jose-Miguel Vela-Hernandez,Manuel Merlos-Roca,Xavier NAVARRO-ACEBES,Mireia HERRANDO-GRABULOSA. Владелец: Esteve Pharmaceuticals SA. Дата публикации: 2024-03-07.

Heterocyclic compounds for use in the treatment of cancer

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Bioactive fractions and compounds from dalbergia sissoo for the prevention or treatment of osteo-health related disorders

Номер патента: WO2012147102A4. Автор: RAKESH Maurya,Girish Kumar Jain,Avinash Kumar,Ritu Trivedi,Naibedya Chattopadhyay,Preety DIXIT,Divya Singh,Vikram KHEDGIKAR,Jyoti GAUTAM,Sheelendra Pratap SINGH,Wahajuddin. Владелец: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH. Дата публикации: 2012-12-27.

Bioactive fractions and compounds from dalbergia sissoo for the prevention or treatment of osteo-health related disorders

Номер патента: WO2012147102A1. Автор: RAKESH Maurya,Girish Kumar Jain,Avinash Kumar,Ritu Trivedi,Naibedya Chattopadhyay,Preety DIXIT,Divya Singh,Vikram KHEDGIKAR,Jyoti GAUTAM,Sheelendra Pratap SINGH,Wahajuddin. Владелец: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH. Дата публикации: 2012-11-01.

Compound for the prophylaxis or treatment of organ damage

Номер патента: CA2986300A1. Автор: Robert Henk Henning,Adrianus Cornelis Van Der Graaf,Leo Edwin DEELMAN,Gerrit Jan Willem Euverink. Владелец: Sulfateq Bv. Дата публикации: 2016-12-01.

Compound for the prophylaxis or treatment of organ damage

Номер патента: CA2986300C. Автор: Robert Henk Henning,Adrianus Cornelis Van Der Graaf,Leo Edwin DEELMAN,Gerrit Jan Willem Euverink. Владелец: Sulfateq Bv. Дата публикации: 2024-02-20.

Substituted benzfurochromenes and related compounds for the prevention and treatment of bone related disorders

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Substituted benzfurochromenes and related compounds for the prevention and treatment of bone related disorders

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Substituted benzfurochromenes and related compounds for the prevention and treatment of bone related disorders

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Anticoronavirus therapeutic agent - substituted 7-hydroxy-3,4,12,12a-tetrahydro-1h-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione for the prevention and treatment of covid-19

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Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of disorders related thereto

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Inositol derivatives for the detection and treatment of alzheimer' s disease and related disorders

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Novel derivatives of psammaplin a, a method for their synthesis and their use for the prevention or treatment of cancer

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Novel Derivatives of Psammaplin A, A Method For Their Synthesis And Their Uses For The Prevention Or Treatment Of Cancer

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Derivatives of psammaplin a, a method for their synthesis and their use for the prevention or treatment of cancer

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Pim kinase inhibitors for treatment of myeloproliferative neoplasms and fibrosis associated with cancer

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Methods and systems for the diagnosis and treatment of androgen disorders

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Medicinal natural product from alternanthera sessilis for the prevention and treatment of anemia and other hematologic disorders, and process for the preparation thereof

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Agent for the prevention and treatment of liver diseases containing pyrazolopyrimidinone derivative

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Process for isolating and producing antibodies for the prevention and treatment of covid-19 and related diseases from blood plasma containing said antibodies

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Novel composition and methods for the treatment of psoriasis

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ANTAGONIST ANTIBODIES AGAINST GDF-8 AND USES IN TREATMENT OF ALS AND OTHER GDF-8 ASSOCIATED DISORDERS

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