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TARGETING THE mTOR PATHWAY IN NEUROLOGICAL DISEASE

Номер патента: WO2014145857A1
Опубликовано: 18-09-2014
Автор(ы): Joseph A. Gogos, Maria Karayiorgou, Sander MARKX
Принадлежит: The Trustees of Columbia University in the City of New York
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Рисунок 1. Взаимосвязь патентов (ближайшие 20).

Therapeutic targeting of the mtor pathway in neurodevelopmental and neuropsychiatric disease

Номер патента: US20160089377A1. Автор: Maria Karayiorgou,Joseph A. Gogos,Sander MARKX. Владелец: Columbia University in the City of New York. Дата публикации: 2016-03-31.

Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the pi3k-akt mtor pathway

Номер патента: CA2815363A1. Автор: Che-Leung Law,Timothy S. Lewis,Julie A. Mcearchern. Владелец: Seattle Genetics Inc. Дата публикации: 2012-04-26.

Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the pi3k-akt mtor pathway

Номер патента: US20240131176A1. Автор: Che-Leung Law,Timothy S. Lewis,Julie A. Mcearchern. Владелец: Seagen Inc. Дата публикации: 2024-04-25.

COMBINATION THERAPY COMPRISING GSPT1-DIRECTED MOLECULAR GLUE DEGRADERS AND PI3K/AKT/mTOR PATHWAY INHIBITORS

Номер патента: WO2024015855A1. Автор: Silvia Buonamici,Michael Song,Ralph TIEDT,Agustin CHICAS,Gerald GAVORY. Владелец: Monte Rosa Therapeutics, Inc.. Дата публикации: 2024-01-18.

SYNERGISTIC EFFECTS BETWEEN AURISTATIN-BASED ANTIBODY DRUG CONJUGATES AND INHIBITORS OF THE PI3K-AKT MTOR PATHWAY

Номер патента: US20160220693A1. Автор: Law Che-Leung,Lewis Timothy S.,McEarchern Julie A.. Владелец: . Дата публикации: 2016-08-04.

Synergistic Effects Between Auristatin-Based Antibody Drug Conjugates And Inhibitors Of The PI3K-AKT mTOR Pathway

Номер патента: US20130209496A1. Автор: Che-Leung Law,Timothy S. Lewis,Julie A. Mcearchern. Владелец: Seattle Genetics Inc. Дата публикации: 2013-08-15.

SYNERGISTIC EFFECTS BETWEEN AURISTATIN-BASED ANTIBODY DRUG CONJUGATES AND INHIBITORS OF THE PI3K-AKT MTOR PATHWAY

Номер патента: US20190184029A1. Автор: Law Che-Leung,Lewis Timothy S.,McEarchern Julie A.. Владелец: . Дата публикации: 2019-06-20.

Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the p13k-akt mtor pathway

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Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the pi3k-akt mtor pathway

Номер патента: WO2012054748A2. Автор: Che-Leung Law,Timothy S. Lewis,Julie A. Mcearchern. Владелец: Seattle Genetics, Inc.. Дата публикации: 2012-04-26.

Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the pi3k-akt mtor pathway

Номер патента: EP2629801B1. Автор: Che-Leung Law,Timothy S. Lewis,Julie A. Mcearchern. Владелец: Seattle Genetics Inc. Дата публикации: 2019-05-15.

Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the pi3k-akt mtor pathway

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Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the PI3K-AKT mTOR pathway

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Use of small molecule inhibitors targeting the interaction between rac gtpase and p67 (phox)

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THERAPEUTIC TARGETING OF THE MTOR PATHWAY IN NEURODEVELOPMENTAL AND NEUROPSYCHIATRIC DISEASE

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combinations and pharmaceutical compositions comprising a P13K/mTOR pathway inhibiting compound

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Target the method in the transcription control in super enhancer region

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Compounds targeting the vegf and/or hif pathway such as sorafenib or vatalanib for use in the treatment of otitis media

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The target system will be made up of a dry fire training gun, a mother target and slave target and importantly the phone Ap. When you fire at the target the Ap will call out your score. If you hit the 10 the target will full backwards and reset it’s self. When the laser from the gun hits the outer rings on the target other than the 10 (bullseye) the Ap will call and record the score on the Ap.

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D40 or CASC5, or a gene encoding the splicing isoform protein of the cancer / testis antigen protein, a method of inducing cancer cell proliferation / mitosis inhibition and cell death targeting the gene product, and Screening method for substances that induce cell division and cell death

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