Peptides derivatives possessing therapeutic activity
Номер патента: MD1591B2
Опубликовано: 31-01-2001
Автор(ы): John E Taylor, Sun Hyuk Kim, Susan Riley Keyes, Sylviane Moreau, Zhengxin Dong
Принадлежит: Biomeasure, Inc.
Опубликовано: 31-01-2001
Автор(ы): John E Taylor, Sun Hyuk Kim, Susan Riley Keyes, Sylviane Moreau, Zhengxin Dong
Принадлежит: Biomeasure, Inc.
Реферат: The invention refers to biologically active peptides derivatives, utilized in medicine, in particular, in oncology.The problem of the invention consists in obtaining of some peptides derivatives possessing high biologic and prolongation activity used for cancer treatment.The biologic peptides derivatives according to the invention, contain one or more cyclic or acyclic substituents including radicals of different chemical nature, where at least one of peptides is linked to each of substituents by the link CO-N, CH2-N or SO2-N between substituent and nitrogen atom either of N-termination or of one of peptides lateral chain.The derivatives modified in a such manner possess a more enchanced and prolonged biologic activity and may be used in the therapeutic quantities for cancer treatment.
Peptide derivative, method of treatment of cancer patient
Номер патента: RU2133252C1. Автор: Сун Хьюк Ким,Женксин Дон,Джон Э. Тейлор,Силвиан Моро,Сьюзан Райли Киз. Владелец: Байомежер, Инк.. Дата публикации: 1999-07-20.