Immortalized human cell lines containing exogenous cytochrome P450 gene
Номер патента: AU6914594A
Опубликовано: 12-12-1994
Автор(ы): Andrea M.A. Pfeifer, Curtis C. Harris, Frank J Gonzalez, Harry V Gelboin, Katharine C Mace
Принадлежит: Nestec SA, US Department of Health and Human Services
Опубликовано: 12-12-1994
Автор(ы): Andrea M.A. Pfeifer, Curtis C. Harris, Frank J Gonzalez, Harry V Gelboin, Katharine C Mace
Принадлежит: Nestec SA, US Department of Health and Human Services
Реферат: Non-tumorigenic, stable, human bronchial and liver epithelial cell lines are provided wherein the cell lines are capable of expressing human cytochrome P450 genes which have been inserted into the cell lines. Also provided are methods and kits for identifying potential mutagens, cytotoxins, carcinogens, chemotherapeutic and chemo-preventive agents utilizing these cell lines.
Cell lines expressing inserted secretable reporter genes at multiple stages of differentiation
Номер патента: US20220002822A1. Автор: James M. Stafford,Michael R. Rountree. Владелец: Nzumbe Inc. Дата публикации: 2022-01-06.