Heterodimeric psma and cd3-binding bispecific antibodies
Номер патента: EP4255574A1
Опубликовано: 11-10-2023
Автор(ы): David Leonard BIENVENUE, Gabriela HERNANDEZ-HOYOS, Jane Gross, Lynda Misher, Peter Pavlik
Принадлежит: APTEVO RESEARCH AND DEVELOPMENT LLC
Опубликовано: 11-10-2023
Автор(ы): David Leonard BIENVENUE, Gabriela HERNANDEZ-HOYOS, Jane Gross, Lynda Misher, Peter Pavlik
Принадлежит: APTEVO RESEARCH AND DEVELOPMENT LLC
Реферат: The present disclosure relates to antibodies that specifically bind to a tumor-associated antigen (TAA) such as PSMA and/or CD3, including bispecific antibodies that bind to a TAA (e.g., PSMA( and CD3, and compositions comprising the same. These antibodies are useful for enhancing immune responses and for the treatment of disorders, including solid tumor cancers, for example, by increasing tumor localization.
Tumor-associated antigens and cd3-binding proteins, related compositions, and methods
Номер патента: US20240301086A1. Автор: David Leonard BIENVENUE,Gabriela HERNANDEZ-HOYOS,Lynda Misher,Peter Pavlik,Jane Gross. Владелец: APTEVO RESEARCH AND DEVELOPMENT LLC. Дата публикации: 2024-09-12.