Cell-free dna for assessing and/or treating cancer.

Cell-free dna for assessing and/or treating cancer

Номер патента: US20210254152A1
Опубликовано: 19-08-2021
Автор(ы): Alessandro Leal, Jacob Fiksel, Jillian A. Phallen, Robert B. SCHARPF, Stephen Cristiano, Victor E. Velculescu, Vilmos Adleff
Принадлежит: JOHNS HOPKINS UNIVERSITY
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Рисунок 1. Взаимосвязь патентов (ближайшие 20).

Cell-free dna for assessing and/or treating cancer

Номер патента: EP3794348A1. Автор: Victor E. Velculescu,Vilmos Adleff,Jillian A. Phallen,Robert B. SCHARPF,Stephen Cristiano,Alessandro Leal,Jacob Fiksel. Владелец: JOHNS HOPKINS UNIVERSITY. Дата публикации: 2021-03-24.

Cell-free dna for assessing and/or treating cancer

Номер патента: US20200131571A1. Автор: Victor E. Velculescu,Vilmos Adleff,Jillian A. Phallen,Robert B. SCHARPF,Stephen Cristiano,Alessandro Leal,Jacob Fiksel. Владелец: JOHNS HOPKINS UNIVERSITY. Дата публикации: 2020-04-30.

Cell-free dna for assessing and/or treating cancer

Номер патента: US20210254152A1. Автор: Victor E. Velculescu,Vilmos Adleff,Jillian A. Phallen,Robert B. SCHARPF,Stephen Cristiano,Alessandro Leal,Jacob Fiksel. Владелец: JOHNS HOPKINS UNIVERSITY. Дата публикации: 2021-08-19.

Cell-free dna for assessing and/or treating cancer

Номер патента: US20220325343A1. Автор: Victor E. Velculescu,Vilmos Adleff,Jillian A. Phallen,Robert B. SCHARPF,Stephen Cristiano,Alessandro Leal,Jacob Fiksel. Владелец: JOHNS HOPKINS UNIVERSITY. Дата публикации: 2022-10-13.

CELL-FREE DNA AS A THERAPEUTIC TARGET FOR FEMALE INFERTILITY AND DIAGNOSTIC MARKER

Номер патента: US20150246103A1. Автор: HAZOUT André. Владелец: . Дата публикации: 2015-09-03.

Blood cell-free dna-based method for predicting prognosis of breast cancer treatment

Номер патента: EP4447069A1. Автор: Min Hwan Kim,Jin Mo AHN,Junnam LEE,Tae-Rim Lee,Eun-Hae CHO,Joohyuk SOHN,Gun Min Kim. Владелец: GC Genome Corp. Дата публикации: 2024-10-16.

Artificial-intelligence-based method for detecting tumor-derived mutation of cell-free dna, and method for early diagnosis of cancer, using same

Номер патента: US20240194294A1. Автор: Eun Hae CHO,Jung Kyoon Choi,Gyuhee KIM. Владелец: GC Genome Corp. Дата публикации: 2024-06-13.

Artificial-intelligence-based method for detecting tumor-derived mutation of cell-free dna, and method for early diagnosis of cancer, using same

Номер патента: EP4318493A1. Автор: Eun Hae CHO,Jung Kyoon Choi,Gyuhee KIM. Владелец: GC Genome Corp. Дата публикации: 2024-02-07.

Identification of somatic or germline origin for cell-free dna

Номер патента: EP3625341A1. Автор: Geoffrey R. Oxnard,Richard B. LANMAN. Владелец: Guardant Health Inc. Дата публикации: 2020-03-25.

Identification of somatic or germline origin for cell-free dna

Номер патента: EP4461826A2. Автор: Geoffrey R. Oxnard,Richard B. LANMAN. Владелец: Guardant Health Inc. Дата публикации: 2024-11-13.

Fragment size characterization of cell-free DNA mutations from clonal hematopoiesis

Номер патента: US12054712B2. Автор: Tingting Jiang. Владелец: Illumina Inc. Дата публикации: 2024-08-06.

Fragment size characterization of cell-free DNA mutations from clonal hematopoiesis

Номер патента: AU2020364225B2. Автор: Tingting Jiang. Владелец: Illumina Inc. Дата публикации: 2023-10-19.

Improving cell-free dna quality

Номер патента: WO2020083267A1. Автор: Peiyong Jiang,Yuk-Ming Dennis Lo,Rossa Wai Kwun Chiu,Cheuk Ho TSANG,Si Long VONG. Владелец: The Chinese University of Hong Kong. Дата публикации: 2020-04-30.

Cell-free DNA quality

Номер патента: US11926821B2. Автор: Peiyong Jiang,Yuk-Ming Dennis Lo,Rossa Wai Kwun Chiu,Cheuk Ho TSANG,Si Long VONG. Владелец: Chinese University of Hong Kong CUHK. Дата публикации: 2024-03-12.

Gut microbiomes and assessing and treating cancer

Номер патента: WO2024144862A1. Автор: Purna C. Kashyap,Thomas E. Witzig,N. Nora BENNANI. Владелец: Mayo Foundation for Medical Education and Research. Дата публикации: 2024-07-04.

Use of deoxyribonuclease i in the treatment of endometriosis in patients with an epigenetic signature of endometriosis on cell-free dna

Номер патента: CA3205788A1. Автор: Andre Hazout,Moncef BEN KHALIFA. Владелец: Endolife. Дата публикации: 2022-07-14.

An ubiquitin ligase inhibitor for use for preventing and/or treating a disease linked with cerebral hypoperfusion

Номер патента: WO2021123143A1. Автор: Thierry COUFFINHAL,Cécile DUPLAA,Jean-Luc Morel,Bruno BONTEMPI. Владелец: Universite de Bordeaux. Дата публикации: 2021-06-24.

An ubiquitin ligase inhibitor for use for preventing and/or treating a disease linked with cerebral hypoperfusion

Номер патента: EP4077673A1. Автор: Thierry COUFFINHAL,Cécile DUPLAA,Jean-Luc Morel,Bruno BONTEMPI. Владелец: Universite de Bordeaux. Дата публикации: 2022-10-26.

Compositions for preventing and/or treating an infection by an HIV-1 virus

Номер патента: US09802983B2. Автор: Vincent Vieillard,Patrice Debre. Владелец: Institut National de la Sante et de la Recherche Medicale INSERM. Дата публикации: 2017-10-31.

Methods and products for preventing and/or treating metastatic cancer

Номер патента: US09718887B2. Автор: Mark Smyth,Shaun Reuss Mccoll,Ian Comerford,Yuka Harata-Lee. Владелец: ADELAIDE RESEARCH AND INNOVATION PTY LTD. Дата публикации: 2017-08-01.

Composition for preventing and/or treating infection, caused by hiv-1

Номер патента: RU2603262C2. Автор: Патрис ДЕБР,Венсан ВЬЕЙАР. Владелец: Иннавирвакс. Дата публикации: 2016-11-27.

Lactobacillus crispatus capable of preventing and/or treating cervical squamous cell carcinoma (cscc)

Номер патента: LU502665A1. Автор: Ming Li,Yan Ma,Ruonan LI,Huiyan Wang,Xixi Chen. Владелец: Anhui Provincial Cancer Hospital. Дата публикации: 2022-08-18.

Lactobacillus crispatus capable of preventing and/or treating cervical squamous cell carcinoma (cscc)

Номер патента: LU502665B1. Автор: Huiyan Wang. Владелец: Anhui Provincial Cancer Hospital. Дата публикации: 2022-12-12.

Compositions, methods, apparatus and products comprising a stathmin/oncoprotein 18 sequence for detecting and treating cancer

Номер патента: US20040101836A1. Автор: Jing Wang,Nikhil Munshi. Владелец: Individual. Дата публикации: 2004-05-27.

An ubiquitin ligase inhibitor for use for preventing and/or treating a disease linked with cerebral hypoperfusion

Номер патента: US20230017666A1. Автор: Thierry COUFFINHAL,Cécile DUPLAA,Jean-Luc Morel,Bruno BONTEMPI. Владелец: Universite de Bordeaux. Дата публикации: 2023-01-19.

Compositions for preventing and/or treating an infection by an hiv-1 virus

Номер патента: CA2831258C. Автор: Vincent Vieillard,Patrice Debre. Владелец: Institut National de la Sante et de la Recherche Medicale INSERM. Дата публикации: 2020-07-14.

Methods and products for preventing and/or treating metastatic cancer

Номер патента: AU2018202318B2. Автор: Mark Smyth,Shaun Reuss Mccoll,Ian Comerford,Yuka Harata-Lee. Владелец: ADELAIDE RESEARCH AND INNOVATION PTY LTD. Дата публикации: 2020-02-13.

Methods for assessing cellular or tissue injury using mitochondrial and/or nuclear cell-free dna

Номер патента: EP4330425A1. Автор: Michael Mitchell,Aoy Tomita Mitchell. Владелец: MEDICAL COLLEGE OF WISCONSIN. Дата публикации: 2024-03-06.

Methods for assessing cellular or tissue injury using mitochondrial and/or nuclear cell-free dna

Номер патента: WO2022232439A1. Автор: Michael Mitchell,Aoy Tomita Mitchell. Владелец: THE MEDICAL COLLEGE OF WISCONSIN, INC.. Дата публикации: 2022-11-03.

Methods for assessing cellular or tissue injury using mitochondrial and/or nuclear cell-free dna

Номер патента: US20240175071A1. Автор: Michael Mitchell,Aoy Tomita Mitchell. Владелец: MEDICAL COLLEGE OF WISCONSIN. Дата публикации: 2024-05-30.

Molecular analyses using long cell-free dna molecules for disease classification

Номер патента: CA3239063A1. Автор: Kwan Chee Chan,Peiyong Jiang,Yuk-Ming Dennis Lo,Rossa Wai Kwun Chiu,Lok Yee Choy. Владелец: Centre For Novostics. Дата публикации: 2023-06-01.

Molecular analyses using long cell-free dna molecules for disease classification

Номер патента: AU2022395092A1. Автор: Kwan Chee Chan,Peiyong Jiang,Yuk-Ming Dennis Lo,Rossa Wai Kwun Chiu,Lok Yee Choy. Владелец: Centre For Novostics. Дата публикации: 2024-05-16.

Molecular analyses using long cell-free dna molecules for disease classification

Номер патента: AU2022395092A2. Автор: Kwan Chee Chan,Peiyong Jiang,Yuk-Ming Dennis Lo,Rossa Wai Kwun Chiu,Lok Yee Choy. Владелец: Centre For Novostics. Дата публикации: 2024-05-23.

Cell-free dna end characteristics

Номер патента: US20240376527A1. Автор: Kwan Chee Chan,Peiyong Jiang,Yuk-Ming Dennis Lo,Rossa Wai Kwun Chiu,Kun Sun,Wing Yan Chan. Владелец: Grail Inc. Дата публикации: 2024-11-14.

Methods for assessing the severity and progression of sars-cov2 infections using cell-free dna

Номер патента: US20230323455A1. Автор: Charles Chiu,Wei Gu,Iwijn De Vlaminck,Alexandre Pellan CHENG,Matthew Pellan CHENG,Donald Cuong VINH. Владелец: CORNELL UNIVERSITY. Дата публикации: 2023-10-12.

Methods for assessing the severity and progression of sars-cov2 infections using cell-free dna

Номер патента: WO2022020662A3. Автор: Charles Chiu,Wei Gu,Iwijn De Vlaminck,Alexandre Pellan CHENG,Matthew Pellan CHENG,Donald Cuong VINH. Владелец: CORNELL UNIVERSITY. Дата публикации: 2022-03-03.

Detection system and detection method of genomic carcinogenesis information based on cell-free dna

Номер патента: US20240060137A1. Автор: Qi Zhang,Weizhi Chen,Yulong Li,Yuanyuan HONG,Fang Lv,Tiancheng Han,Shunli YANG,Peiyao NIE. Владелец: Genecast (beijing) Biotechnology Co Ltd. Дата публикации: 2024-02-22.

Methods of determining tissues and/or cell types giving rise to cell-free DNA, and methods of identifying a disease or disorder using same

Номер патента: AU2022202587B2. Автор: Jay Shendure,Martin Kircher,Matthew Snyder. Владелец: UNIVERSITY OF WASHINGTON. Дата публикации: 2024-07-04.

Analysis of fragmentation patterns of cell-free dna

Номер патента: EP4279612A3. Автор: Kwan Chee Chan,Peiyong Jiang,Yuk-Ming Dennis Lo,Rossa Wai Kwun Chiu. Владелец: Chinese University of Hong Kong CUHK. Дата публикации: 2024-02-28.

Analysis of fragmentation patterns of cell-free dna

Номер патента: EP4279612A2. Автор: Kwan Chee Chan,Peiyong Jiang,Yuk-Ming Dennis Lo,Rossa Wai Kwun Chiu. Владелец: Chinese University of Hong Kong CUHK. Дата публикации: 2023-11-22.

Assessing risk with pre-operative total cell-free dna

Номер патента: US20230399697A1. Автор: Michael Mitchell,Aoy Tomita Mitchell. Владелец: MEDICAL COLLEGE OF WISCONSIN. Дата публикации: 2023-12-14.

Systems and methods for gene expression and tissue of origin inference from cell-free dna

Номер патента: EP4433611A2. Автор: Mohammad Shahrokh ESFAHANI,Mahya Mehrmohamadi,Maximiliam DIEHN,Arash Ash ALISADEH. Владелец: Leland Stanford Junior University. Дата публикации: 2024-09-25.

Analysis of cell-free DNA in urine and other samples

Номер патента: AU2024201498A1. Автор: Kwan Chee Chan,Peiyong Jiang,Yuk-Ming Dennis Lo,Rossa Wai Kwun Chiu,Hua Tse Timothy CHENG. Владелец: Chinese University of Hong Kong CUHK. Дата публикации: 2024-03-28.

Analysis of cell-free DNA in urine and other samples

Номер патента: AU2021203359B2. Автор: Kwan Chee Chan,Peiyong Jiang,Yuk-Ming Dennis Lo,Rossa Wai Kwun Chiu,Hua Tse Timothy CHENG. Владелец: Chinese University of Hong Kong CUHK. Дата публикации: 2023-12-14.

Methods of determining donor cell-free dna without donor genotype

Номер патента: US20210032692A1. Автор: Aoy Tomita Mitchell,Karl Stamm. Владелец: Tai Diagnostics Inc. Дата публикации: 2021-02-04.

Methods of determining donor cell-free dna without donor genotype

Номер патента: EP3668995A1. Автор: Aoy Tomita Mitchell,Karl Stamm. Владелец: Tai Diagnostics Inc. Дата публикации: 2020-06-24.

Methods of determining donor cell-free DNA without donor genotype

Номер патента: AU2018317875A1. Автор: Aoy Tomita Mitchell,Karl Stamm. Владелец: Tai Diagnostics Inc. Дата публикации: 2020-03-05.

Methods of determining tissues and/or cell types giving rise to cell-free dna, and methods of identifying a disease or disorder using same

Номер патента: US20230212672A1. Автор: Jay Shendure,Martin Kircher,Matthew Snyder. Владелец: UNIVERSITY OF WASHINGTON. Дата публикации: 2023-07-06.

Highly sensitive surveillance using detection of cell free dna

Номер патента: CA2870969C. Автор: Michael Mitchell,Aoy Tomita Mitchell. Владелец: MEDICAL COLLEGE OF WISCONSIN. Дата публикации: 2023-10-03.

Cell-free dna end characteristics

Номер патента: EP4300500A2. Автор: Kwan Chee Chan,Peiyong Jiang,Yuk-Ming Dennis Lo,Rossa Wai Kwun Chiu,Kun Sun,Wing Yan Chan. Владелец: Grail LLC. Дата публикации: 2024-01-03.

Compositions and methods for isolating cell-free dna

Номер патента: US20230323474A1. Автор: Andrew Kennedy,Matthew Schultz,William J. GREENLEAF,Ariel JAIMOVICH. Владелец: Guardant Health Inc. Дата публикации: 2023-10-12.

Cell-free dna end characteristics

Номер патента: EP4300500A3. Автор: Kwan Chee Chan,Peiyong Jiang,Yuk-Ming Dennis Lo,Rossa Wai Kwun Chiu,Kun Sun,Wing Yan Chan. Владелец: Grail Inc. Дата публикации: 2024-03-27.

De novo characterization of cell-free dna fragmentation hotspots in healthy and early-stage cancers

Номер патента: WO2021262770A1. Автор: Yaping Liu,Haizi ZHENG,Xionghui Zhou. Владелец: Children's Hospital Medical Center. Дата публикации: 2021-12-30.

Delfi-derived cell-free dna fragmentation patterns differentiate histologic subtypes of lung cancers in a non-invasive manner

Номер патента: WO2024173277A2. Автор: Lorenzo RINALDI,Zachary L. SKIDMORE. Владелец: Delfi Diagnostics, Inc.. Дата публикации: 2024-08-22.

Delfi-derived cell-free dna fragmentation patterns differentiate histologic subtypes of lung cancers in a non-invasive manner

Номер патента: WO2024173277A3. Автор: Lorenzo RINALDI,Zachary L. SKIDMORE. Владелец: Delfi Diagnostics, Inc.. Дата публикации: 2024-10-24.

Aorta-specific dna methylation patterns in cell-free dna from patients with bicuspid aortic valve-associated aortopathy

Номер патента: US20230265493A1. Автор: Steven GREENWAY,Paul W.M. FEDAK,Ashna Karimbhai MAREDIA,Mohammad ALEINATI. Владелец: UTI LP. Дата публикации: 2023-08-24.

Aorta-specific dna methylation patterns in cell-free dna from patients with bicuspid aortic valve-associated aortopathy

Номер патента: CA3142851A1. Автор: Steven GREENWAY,Ashna Karimbhai MAREDIA,Mohammad ALEINATI,Paul W. M. Fedak. Владелец: UTI LP. Дата публикации: 2023-06-17.

Systems and methods for distinguishing pathological mutations from clonal hematopoietic mutations in plasma cell-free dna by fragment size analysis

Номер патента: US20230114365A1. Автор: Wai Yi Tsui,Francesco MARASS,Luis Diaz, JR.. Владелец: Memorial Sloan Kettering Cancer Center. Дата публикации: 2023-04-13.

Determining cell, tissue, or lesion representations in cell-free dna

Номер патента: US20210005282A1. Автор: Kahn Rhrissorrakrai,Filippo UTRO,Chaya LEVOVITZ,Laxmi Parida. Владелец: International Business Machines Corp. Дата публикации: 2021-01-07.

Epigenetics analysis of cell-free dna

Номер патента: WO2024022529A1. Автор: Lu Ji,Kwan Chee Chan,Peiyong Jiang,Yuk-Ming Dennis Lo,Masashi Yukawa,Jinyue BAI. Владелец: Centre For Novostics. Дата публикации: 2024-02-01.

Detecting hematological disorders using cell-free dna in blood

Номер патента: EP4324937A2. Автор: Kwan Chee Chan,Yuk-Ming Dennis Lo,Rossa Wai Kwun Chiu,Kun Sun. Владелец: Chinese University of Hong Kong CUHK. Дата публикации: 2024-02-21.

Epigenetics analysis of cell-free dna

Номер патента: US20240043935A1. Автор: Lu Ji,Kwan Chee Chan,Peiyong Jiang,Yuk-Ming Dennis Lo,Masashi Yukawa,Jinyue BAI. Владелец: Centre For Novostics Ltd. Дата публикации: 2024-02-08.

Detecting hematological disorders using cell-free dna in blood

Номер патента: EP4324937A3. Автор: Kwan Chee Chan,Yuk-Ming Dennis Lo,Rossa Wai Kwun Chiu,Kun Sun. Владелец: Chinese University of Hong Kong CUHK. Дата публикации: 2024-05-15.

Quantification of transplant-derived circulating cell-free dna in the absence of a donor genotype

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Determining a physiological condition in an individual by analyzing cell-free dna fragment endpoints in a biological sample

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Cell-free dna signals as biomarkers of preeclampsia

Номер патента: WO2024173756A1. Автор: SUNG Kim,Sucheta Dhananjay BHATT,Theresa Ann BOOMER,Jean GEKAS,Weida GONG,Christina Ngoc Bich NGUYEN. Владелец: Illumina, Inc.. Дата публикации: 2024-08-22.

Fluorescence Detection of Circulating Cell Free DNA Including Within Extracellular Vesicles in Biospecimens and Liquid Biopsies

Номер патента: US20240102995A1. Автор: Massoud Motamedi,Stefan H. Bossmann,Bartosz Szczesny. Владелец: Kansas State University. Дата публикации: 2024-03-28.

Detection of somatic mutational signatures from whole genome sequencing of cell-free dna

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Determining a physiological condition in an individual by analyzing cell-free dna fragment endpoints in a biological sample

Номер патента: EP4450648A2. Автор: Jay Shendure,Matthew William SNYDER. Владелец: Bellwether Bio Inc. Дата публикации: 2024-10-23.

Systems and methods for gene expression and tissue of origin inference from cell-free dna

Номер патента: WO2023091517A3. Автор: Arash Ash Alizadeh,Maximilian Diehn,Mohammad Shahrokh ESFAHANI,Mahya Mehrmohamadi. Владелец: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY. Дата публикации: 2023-07-06.

Single molecule sequencing and methylation profiling of cell-free dna

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Systems and methods for gene expression and tissue of origin inference from cell-free dna

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Methods to predict outcomes to chimeric antigen receptor t-cells in lymphoma from cell-free dna and genetic mutations

Номер патента: US20230383361A1. Автор: Crystal Mackall,Arash Ash Alizadeh,David M. Kurtz,Maximilian Diehn,Matthew Frank,Brian SWORDER,David B. Miklos. Владелец: Leland Stanford Junior University. Дата публикации: 2023-11-30.

Improved methods for neoplasia detection from cell free dna

Номер патента: WO2023164558A2. Автор: Donald Stewart,Gad Getz,Ziao LIN. Владелец: THE BROAD INSTITUTE, INC.. Дата публикации: 2023-08-31.

Methods of determining tissues and/or cell types giving rise to cell-free dna, and methods of identifying a disease or disorder using same

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Improved methods for neoplasia detection from cell free dna

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Compositions and methods for reducing cell-free dna

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REAGENTS FOR DETECTING ALU ELEMENTS IN CELL-FREE DNA (cfDNA)

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REAGENTS FOR DETECTING ALU ELEMENTS IN CELL-FREE DNA (cfDNA)

Номер патента: US20220333182A1. Автор: Minnie M. Sarwal,Joshua Y. YANG,Tara K. SIGDEL. Владелец: UNIVERSITY OF CALIFORNIA. Дата публикации: 2022-10-20.

Determining of health status and treatment monitoring with cell-free dna

Номер патента: WO2024056720A1. Автор: Michael Speicher,Martin Kircher,Samantha HASENLEITHNER,Benjamin SPIEGL. Владелец: Medizinische Universitat Graz. Дата публикации: 2024-03-21.

Detection and quantification of donor cell-free dna in the circulation of organ transplant recipients

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Detection and quantification of donor cell-free DNA in the circulation of organ transplant recipients

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Using cell-free dna fragment size to determine copy number variations

Номер патента: EP3230469A1. Автор: Richard P. Rava,David A. COMSTOCK,Sven Duenwald,Catalin Barbacioru,Darya I. Chudova. Владелец: Verinata Health Inc. Дата публикации: 2017-10-18.

Detection of somatic mutational signatures from whole genome sequencing of cell-free dna

Номер патента: AU2022300887A1. Автор: JR. Luis A. DIAZ,Jonathan Chee Ming WAN. Владелец: Memorial Hospital for Cancer and Allied Diseases. Дата публикации: 2024-01-25.

Methods and systems for cell-free dna fragment size densities to assess cancer

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Preventing and/or treating diabetes mellitus

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Method and driver assistance system for assessing and/or maintaining the alertness of a driver of a vehicle

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