Methods for modulation of and sensitization to serine and glycine limitation
Номер патента: CA3205385A1
Опубликовано: 23-06-2022
Автор(ы): Karen Vousden, Oliver D. K. MADDOCKS
Принадлежит: Cancer Research Technology LTD, Faeth Therapeutics Inc
Опубликовано: 23-06-2022
Автор(ы): Karen Vousden, Oliver D. K. MADDOCKS
Принадлежит: Cancer Research Technology LTD, Faeth Therapeutics Inc
Реферат: Disclosed herein are formulations and methods of administering formulations to starve cells of nutrients, such as amino acids. The formulations of the present invention can be substantially be devoid of one or more amino acid. The formulations of the present invention can be administered in a combination with an amino acid biosynthesis inhibitor or radiotherapy. A method disclosed herein can sensitize a cell to serine and/or glycine depletion.
Methods for modulation of and sensitization to serine and glycine limitation
Номер патента: EP4262787A1. Автор: Karen Vousden,Oliver D.K. Maddocks. Владелец: Faeth Therapeutics Inc. Дата публикации: 2023-10-25.