Depletion of activated hepatic stellate cells (hscs) and uses thereof
Номер патента: EP4363443A1
Опубликовано: 08-05-2024
Автор(ы): Chris Xiangyang Lu, Minhua Zhang, Ruipeng ZHANG, Xiang-Ju Justin Gu
Принадлежит: Laekna Therapeutics Shanghai Co Ltd
Опубликовано: 08-05-2024
Автор(ы): Chris Xiangyang Lu, Minhua Zhang, Ruipeng ZHANG, Xiang-Ju Justin Gu
Принадлежит: Laekna Therapeutics Shanghai Co Ltd
Реферат: A binding molecule comprising a binding domain that binds to an antigen expressed on an activated hepatic stellate cells (HSC), and a functional domain that is capable of enhancing an antibody effector function such as antibody-dependent cell-mediated cytotoxicity (ADCC) toward activated HSCs. Uses of such binding molecule are also provided herein.
Depletion of activated hepatic stellate cells (hscs) and uses thereof
Номер патента: CA3222788A1. Автор: Chris Xiangyang Lu,Minhua Zhang,Xiang-Ju Justin Gu,Ruipeng ZHANG. Владелец: Laekna Therapeutics Shanghai Co Ltd. Дата публикации: 2023-01-05.