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Nmr quantification of tmao

Номер патента: EP2859338A1
Опубликовано: 15-04-2015
Автор(ы): Dennis W. Bennett, Elias J. Jeyarajah, James D. Otvos, Justyna E. WOLAK-DINSMORE, Steven P. Matyus, Thomas M. O'CONNELL
Принадлежит: Liposcience Inc

Реферат: A defined peak region residing between about 3.2 and 3.4 ppm of a proton NMR spectrum of an in vitro biosample is electronically evaluated to determine a level of trimethylamine-N-oxide ("TMAO"). The biosamples may be any suitable biosamples including human serum with a normal biologic range of between about 1-50 µM or urine with a normal biologic range of between about 0-1000 µM.

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