Alzheimer's disease early diagnosis and/or prognosis in circulating immune cells based on heparan sulfates and/or of heparan sulfate sulfotransferases
Номер патента: EP3430408A1
Опубликовано: 23-01-2019
Автор(ы): Alexandre FIFRE, Bruno Dubois, Dulce PAPY-GARCIA, Francis NYASSE, Mohand Ouidir OUIDJA, Patricia Albanese, Sandrine CHANTEPIE-LABORDE
Принадлежит: Assistance Publique Hopitaux de Paris APHP, Universite Paris Est Creteil Paris 12
Опубликовано: 23-01-2019
Автор(ы): Alexandre FIFRE, Bruno Dubois, Dulce PAPY-GARCIA, Francis NYASSE, Mohand Ouidir OUIDJA, Patricia Albanese, Sandrine CHANTEPIE-LABORDE
Принадлежит: Assistance Publique Hopitaux de Paris APHP, Universite Paris Est Creteil Paris 12
Реферат: The present invention relates to a method of prognosis and/or diagnosis of Alzheimer's disease by determining the level and/or cellular distribution of heparan sulfates (HS) and/or heparan sulfate sulfotransferases (HSSTs) from isolating circulating immune cells in said circulating immune cells.
Cortical neuron cell model of alzheimer's disease based on bmi1 deficiency, and uses thereof
Номер патента: US20190203254A1. Автор: Gilbert Bernier,Anthony Flamier. Владелец: 9636137 Canada Inc. Дата публикации: 2019-07-04.