Tropomyosin receptor kinase (trk) degradation compounds and methods of use
Номер патента: EP4110772A1
Опубликовано: 04-01-2023
Автор(ы): Chengwei Zhang, Jialiang Wang, Jing Liu, Liqun Chen, Michael Bruno Plewe, Xiaoran HAN
Принадлежит: Cullgen Shanghai Inc
Опубликовано: 04-01-2023
Автор(ы): Chengwei Zhang, Jialiang Wang, Jing Liu, Liqun Chen, Michael Bruno Plewe, Xiaoran HAN
Принадлежит: Cullgen Shanghai Inc
Реферат: This disclosure relates to bivalent compounds (e.g., bi-functional small molecule compounds), compositions comprising one or more of the bivalent compounds, and to methods of use the bivalent compounds for the treatment of certain disease in a subject in need thereof. The disclosure also relates to methods for identifying such bivalent compounds.
Tropomyosin receptor kinase (TRK) degradation compounds and methods of use
Номер патента: AU2021225981A1. Автор: Jing Liu,Michael Bruno Plewe,Liqun Chen,Jialiang Wang,Xiaoran HAN,Chengwei Zhang. Владелец: Cullgen Shanghai Inc. Дата публикации: 2022-09-29.