Amorphous form of chelating agents and process for preparing them
Опубликовано: 11-08-2021
Автор(ы): Antonio Parreira, Rafael ANTUNES, Sara SEQUEIRA, Susana SALDANHA
Принадлежит: Hovione Scientia Ltd
Реферат: An amorphous form of a chelating agent is provided, in particular wherein the chelating agent comprises ethylenediaminetetraacetic acid/edetic acid (EDTA), diethylenetriaminepentaacetic acid/pentetic acid (DTPA), nitrilotriacetic acid (NTA), amino tris(methylenephosphonic acid) (ATMP), ethylenediamine tetramethylene phosphonic acid (EDTMP), 1-hydroxyethane 1,1-diphosphonic acid (HEDP), ethylenediaminedisuccinic acid (EDDS), iminodisuccinic acid (IDS), hydroxamic acid, oxalic acid, galactaric acid, metaphosphoric acid, or phytic acid, or a salt of any one or more of the above acids, or a mixture of two or more of any of the above acids or salts thereof. A process for preparing an amorphous form of a chelating agent comprises the steps of: a) Dissolving the chelating agent in a suitable solvent; b) Optionally purifying the solution; c) Isolating an amorphous form of the chelating agent; d) Optionally post drying or conditioning the amorphous form of the chelating agent.
Amorphous Form of Chelating Agents and Process for Preparing them
Номер патента: US20220002226A1. Автор: Rafael ANTUNES,Antonio Parreira,Sara SEQUEIRA,Susana SALDANHA. Владелец: Hovione Scientia Ltd. Дата публикации: 2022-01-06.