Apol1 inhibitors and methods of use
Номер патента: CA3179178A1
Опубликовано: 25-08-2022
Автор(ы): Adam Neil REID, Birong Zhang, Christopher Joseph Sinz, David John Morgans Jr., Maarten HOEK, Patrick Sang Tae LEE, Sarah M. BRONNER, Todd Jonathan August EWING, Victoria Anne ASSIMON
Принадлежит: Maze Therapeutics Inc
Опубликовано: 25-08-2022
Автор(ы): Adam Neil REID, Birong Zhang, Christopher Joseph Sinz, David John Morgans Jr., Maarten HOEK, Patrick Sang Tae LEE, Sarah M. BRONNER, Todd Jonathan August EWING, Victoria Anne ASSIMON
Принадлежит: Maze Therapeutics Inc
Реферат: Provided herein are compounds of formula (A'): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein X1, X2, X3, X4, Ra, Rb, Rc, L, Q, and Y are as defined herein. Also provided are methods of inhibiting APOL1 and methods of preparing compounds of formula (A'). Also provided are methods of inhibiting APOL1 and methods of treating an APOL1 -mediated disease, disorder, or condition in an individual.
Apol1 inhibitors and methods of use
Номер патента: WO2022178315A1. Автор: Christopher Joseph Sinz,Birong Zhang,Sarah M. BRONNER,David John Morgans Jr.,Patrick Sang Tae LEE,Todd Jonathan August EWING,Adam Neil REID,Maarten HOEK,Victoria Anne ASSIMON. Владелец: Maze Therapeutics, Inc.. Дата публикации: 2022-08-25.