Gene therapy compositions for use in the prevention and/or treatment of non-alcoholic fatty liver disease
Номер патента: EP3068889A1
Опубликовано: 21-09-2016
Автор(ы): Fatima Bosch Tubert, Laia VILÀ PRATS
Принадлежит: Universitat Autonoma de Barcelona UAB
Опубликовано: 21-09-2016
Автор(ы): Fatima Bosch Tubert, Laia VILÀ PRATS
Принадлежит: Universitat Autonoma de Barcelona UAB
Реферат: The present invention relates to the field of gene therapy and, more particularly, to methods for the prevention and/or treatment of non-alcoholic fatty liver disease (NAFLD). The viral vectors disclosed in the present invention are preferably parvoviral vector, more preferably adeno-associted vectors (AAV) containing the gene encoding Sirtuin 1 (Sirt1) in the prevention and/or treatment of NAFLD. The present invention also discloses the pharmaceutical compositions comprising the viral vector and the method of prevention and/or treatment of NAFLD and related diseases by the administration of said pharmaceutical compositions.
Gene therapy compositions for use in the prevention and/or treatment of non-alcoholic fatty liver disease
Номер патента: WO2015044292A8. Автор: Fatima Bosch Tubert,Laia VILÀ PRATS. Владелец: UNIVERSITAT AUTONOMA DE BARCELONA. Дата публикации: 2018-07-12.