Process for the preparation of optically-active compounds
Номер патента: EP1773799A1
Опубликовано: 18-04-2007
Автор(ы): Georg Frater, Urs Mueller
Принадлежит: Givaudan SA
Опубликовано: 18-04-2007
Автор(ы): Georg Frater, Urs Mueller
Принадлежит: Givaudan SA
Реферат: A method of preparing enatiomerically enriched 3a,6,6,9a-tetramethyl-dodecahydro-naphtho[2,1-b]furan, formula (I), from (E,E)-homofarnesic acid or (E)-monocyclohomofarnesic acid by (a) reacting firstly with a chiral alcohol, (b) reacting the product of (a) with an acid to cause a first cyclization, (c) producing an alcohol by reacting the product of (b) with a reducing agent and (d) causing a second cyclization by reacting the product of (c) with an acid. The product of this process gives a mixture of both enantiomers with one in excess.
Optically active chiral compounds, process for their preparation and use of these compounds in the protection of functional -oh, -sh, -nh- groups, in the separation of racemates, in the preparation of optically active imidoester hydrochlorides and of optically active esters, in the preparation of optically enriched alcohols and in the preparation of optically active compounds by asymmetric induction
Номер патента: EP0083335B1. Автор: Christian Dipl.-Ing. Dr. Noe. Владелец: Christian Dipl.-Ing. Dr. Noe. Дата публикации: 1987-08-12.