A process for improving polypeptide expression in mammalian cell culture
Номер патента: EP4413150A1
Опубликовано: 14-08-2024
Автор(ы): Ghanshyam Madhabhai Patel, Kaumil Bhupendra bhai BHAVSAR, Parth Hitarthbhai Vaishnav
Принадлежит: Kashiv Biosciences LLC
Опубликовано: 14-08-2024
Автор(ы): Ghanshyam Madhabhai Patel, Kaumil Bhupendra bhai BHAVSAR, Parth Hitarthbhai Vaishnav
Принадлежит: Kashiv Biosciences LLC
Реферат: The present invention relates to a process of improving the production of anti-IgE antibody specifically Omalizumab with improved titer and reduced galactosylation and/or reduced acidic variant expressed in mammalian cell culture in suitable culture condition for an example using fed batch mode by maintaining specific temperature 36.5° C ± 0.5 throughout the duration of cells culture.
A process for improving polypeptide expression in mammalian cell culture
Номер патента: AU2023223660A1. Автор: Kaumil Bhupendra bhai BHAVSAR,Ghanshyam Madhabhai Patel,Parth Hitarthbhai Vaishnav. Владелец: Kashiv Biosciences LLC. Дата публикации: 2024-08-01.