Improvements in and relating to the production of the antibiotic micrococcin
Номер патента: GB711593A
Опубликовано: 07-07-1954
Автор(ы): Brendan Kevin Kelly, George Arthur Miller, John Marshall Whitmarsh
Принадлежит: National Research Development Corp UK
Опубликовано: 07-07-1954
Автор(ы): Brendan Kevin Kelly, George Arthur Miller, John Marshall Whitmarsh
Принадлежит: National Research Development Corp UK
Реферат: A sterilized medium for the cultivation of a micrococcin-producing micro-organism comprises one or more of the following substances in an aqueous medium, namely: corn steep liquor, Maggi's Bouillon Powder (gelatin, meat extract and hydrolysed casein), soya bean flour hydrolysate, meat meal hydrolysate and a yeast extract (or autolysate or distiller's residue containing yeast), carbohydrates being absent. The yeast extract may be a soluble yeast extract. Casein hydrolysate, fish meal hydrolysate and dried blood may also be present. The nitrogen concentration should be a minimum of 2400 mgms per litre. It is preferred to use a cultivation temperature of 30 DEG C., an initial pH of 6 to 7 and to ferment 2 to 4 days. Tri-amyl citrate may be used as antifoaming agent. The culture is aerated and stirred. Micrococcus NCTC 7128 is the microorganism cultivated in the examples.
Antibiotic 76-11, process for the production thereof, anticoccidiosis agent and domestic animals growth accelerator comprising the same as an effective ingredient
Номер патента: CA1183789A. Автор: Shigeo Fujita,Kiyoshi Isono,Goto Nakamura. Владелец: Kaken Chemical Co Ltd. Дата публикации: 1985-03-12.