Antithrombotic Azacycloalkylalkanoyl peptides and pseudopeptides.

24-11-2000 дата публикации
Номер:
AP0000000904A
Принадлежит: Aventis Pharmaceuticals Products Inc
Контакты:
Номер заявки: 01-00-1999452
Дата заявки: 15-08-1997

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The invention is directed to a non-hygroscopic stable crystalline form of the antithrombotic compound N-[N-[N-(4-piperdin-4-yl)butanoyl)-N-ethylglycyl]-(;)-aspartyl]-(L)-b-cyclohexyl-alanine amide, to processes for preparing said stable crystalline form, to a pharmaceutical composition thereof, and intermediates thereof, and the invention is directed also to processes and intermediates for preparing a compound of formula (II) wherein: A, B, Z, EL, E1, G, R, m, n and p are as defined herein.