Traditional Chinese medicine for treating ichthyosis

Technical Field

The invention belongs to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine for the treatment of ichthyosis.

Background Art

In China and on medical world recognized as within the range of is a kind of high Atopy, current medical experts, researchers have a system and method for the understanding of the treatment, no specific drugs or good treatment method, only can be used as passive infirmary; the disease is a skin disorder keratinization, common with ordinary type ichthyosis, the nature unites ichthyosis, plate lamellar ichthyosis, the above-mentioned three kinds of disease time after birth generally 2 months to 30 months disease, accounting for more than ninety percent of patients fish; acguired ichthyosis and the partner sends the nature ichthyosys occupied kazunari left and right, are extremely rare. The current common methods of treatment have the following conservative conservation therapy: external an emollient and 10% lactic acid ointment, ointment the card anchors mellowly three , the 10% [...] 15% urea frost and ointment, presses acid ointment, he grips Luo Ting , adapalene, cod-liver oil ointment, 40% propylene glycol aqueous solution, -dimensional A the external use scratches acid, and the like, and, for the prevention of skin moisture evaporation, the moisture content of the stratum corneum, oral has different Uygur A acid or Arvie A acid, in accordance with curve for ester , in accordance with curve acid substitution, conservative treatment of serious patients of application; for treating effect is not is not ideal.

Content of the invention

The aim of the invention is to improve the disadvantages of the prior art and provides a traditional Chinese medicine theory according to the past, scientific matching, complementary, to the itch governs itches , principles, and adjust the medical stimulation of skin, muscles, and kill skin epidermal the virus for the treatment of ichthyosis of traditional Chinese medicine.

The purpose of this invention is realized like this, a traditional Chinese medicine for the treatment of ichthyosis, is composed of a weight are 10-20 portions of leaf, 7-17 portions of hydnocarpic, 13-23 mannosan of, 5-15 parts of sulfur, 9-19 portions of fructus cnidii, 8-18 of, 5-15 portions of honeycomb, 11-21 selinum of, 10-20 portions of said sub-composition.

The invention for treating ichthyosis the pharmacological prescription of Chinese traditional Chinese medicine is the basis of the basic theory, principles, in order to offset governing bias, remedy defects and rectify errors, complement each other.

Mugwort leaf: bitter, kissin, sexual temperature. turns over to the liver , sple, the of the kidney. Has dispersing hemostasia, expelling cold tiaojinghuoxue, the efficacy of miscarriage.

Hydnocarpic: kissin, hot, toxic, turns over to the liver , sple, the of the kidney. External brachydanio insectcidal, dampness wind, for leprosis acariases, syphilis.

Fructus Xanthii: kissin, myoporum, wet, with few poisons , on lung through. Wind-dehumidification, treating Tongqiao obtunding. Use for urticarias pruritus, pain, Mange, Leprosy, rheumatism, the four limbs of limbs.

Sulphury: acid, wet, toxic, quai kidney, the large intestine. Detoxifying insectcidal itch stopping, to regulate penetrating pressure defaecations. Use for scabies, sore, eczema, ringworm.

Fructus cnidii: kissin, myoporum, temperature, is for kidney. The itch stopping of parasite killing, spcialized factory. Use for eczema, Mange, unless the rheumatism was mad , Leigh joint, wwe low.

Flavescent sophora root: myoporum, cold. Centering, liver, stomach, colon, bladder through. Heat and drying damp, insecticidal, diuresis. Because of the, blood, jaundice anuresis, leukorrhea, swells cloudy itches cloudy , eczema, eczema, skin pruritus, Mange leprosis; treating trichomonas Vaginitis.

Cellular: Ganong, flat, quai consumed. Brachydanio insectcidal, wind and relieving pain. External yu Yong , gangrene, ringworm, sore, exanthems, pruritus.

Selinum: kissin, heat, Guipi, stomach, kidney through. Windsong pain, itch stopping of parasite killing.

Summer cypress sub-: myoporum, cold, quai bladderscan through. Clearing away heat and promoting diuresis itch stopping. For the external skin urticarias, eczema, pruritus body.

Pharmacological prescription leaf thereof is, warming hemostasia, using cold tiaojinghuoxue; hydnocarpic, toxic, brachydanio insectcidal, dampness wind; fructus Xanthii, wind-dehumidifying, tongluozhitong; sulphury, toxic, and toxic materials insectcidal, antipruritic, to regulate penetrating pressure; fructus cnidii, insectcidal antipruritic, spcialized factory; flavescent sophora root, heat and drying damp, insectcidal diuresis; cellular, tapping poisoning gehin, wind and obtunding; selinum, windsong pain, itch stopping of parasite killing; fructus Kochiae, clearing away heat and promoting diuresis, itch stopping diuresis, in dispels the skin heat.

This invention is by the traditional Chinese herbal medicines made, according to the characteristics of ichthyosis, season the role the law of food and, on this basis and on. Ichthyosis have a common characteristic, that is, excessive keratinization a superficial sraps the grinding, the cell proliferation of epidermal keratinocyte, epidermal replacement time is shortened, or because of the keratinocyte cohesin abnormal, the cells of the stratum corneum can not normally fall off accumulated on the table surface, around the dermis blood lymphocytes or the infiltration of inflammatory cells.

Traditional Chinese medicine of the present invention to the role of the disease can be completely solved the problem of these the most basic, and can promote the growth of new skin, medication 6 days on the layer of the epidermis, thorn level , hair follicle wrangle bolt sraps even automatically fall off the 30% [...] 50% ; 12-15 days basically removed; 15 day -20 days to begin the growth of a human normal gloss sanguineness fine sliding skin. Lighter the 30 [...] 40 days, in the 60 [...] 70 days the patient can obtain a body of normal skin.

The invention is for external use, to a part of the toxic drug, is based on the traditional Chinese medicine theory and, scientific matching, complementary, to the itch governs itches , principles, and adjust the medical stimulation of skin, muscles, and kill skin epidermal the virus. Medication for several years without any poisonous negative role of the patient, the patient after cure to the three levels of a hospital blood-test all indices are all normal, and no recurrence.

The of the Chinese medicine of the invention SUMMARY of the toxicological experiment animals: purpose: of the external observation of the RAT acute and long-term toxicity. Method: SD RAT is a tested object, the 4 a dose (40, 20, 10, 5 ml/kg), RAT iqSD at the same time, continuously wash decoction to 80 days, observation administration 40d-80d the growth of the RAT, blood, blood biochemical, histopathogical change and stop 30d of the above-mentioned index changes when, as a result, dosing 40d-80d stop and 30d rear, RAT body weight, food intake, activities, peripheral hemograms, important zoki coefficient are normal, biochemical inspection: all in the group the same blank group is reduced compared with the albumin (p > 0.05), total protein and creatinine rise (p > 0.05), alkaline phosphatase (ALP) rise (p > 0.05), pathological check each group of all zoki have not found significant change. Conclusion: the toxicological experiment of said-: through said granules in the prescription medication process, various indicators observation of the reaction, no obvious toxic side effects, a comprehensive analysis of view: in the prescribed dosage of the prescription, application is safe and reliable.

Prescription of the present invention multiple patients regardless of the 1 [...] 3 days with instant effect, a itch, the sraps, granular layer and the beginning of the falling of large area [...] use the 10 [...] 15 escapesday completely , 15 days to 20 days the grow out fresh skin, one to two full cure of course, a course of treatment to one month.

The clinical application of traditional Chinese medicine for the treatment of the present invention 100 patients, therapy unit 100 an example, control 100 example, whether the total efficiency and the effective rate, the treatment compared to the control group, the difference is prominent, the statistics bunri P < 0.05; the total efficiency for treating doses and 97%, control group 81% ; for treating sloping efficiency 80%, control 60%. Below is a list of group curative effect is evaluated after treatment the control group:

P < 0.05