틴달화 유산균 사균체를 유효성분으로 포함하는 피부 보습 또는 주름개선용 조성물
The present invention refers to a composition for skin moisturizing or wrinkle tyndall sterilising body including lactic acid active ingredient are disclosed. Always physically damaged skin with the environment external respectively mainly to protect the external organs for human body and chemicals, bacteria, mold, viruses such as amount and prevent skin, moisture loss protection barrier could be bonded each other. The structure of the skin epidermis, dermis, two layers of which the tip weight 3 two layer 3 skin is valuable 22a. responsible and protection of moisturizing the skin layer. In particular epidermal stratum corneum layer of the skin by way of letting water present which is resilient, stratum corneum of elasticity of 10% or more is necessary has been maintained moisture generally known (O. K. Jacobi, Proc. Sci. Sec. Toilet Goods Assoc. 1959, 31, 22). For example recent, more water to environmental pollution is prevented from being exposed to ultra-violet against GDNF is strong, the moisture vapor and is accelerated while skin aging skin, skin along incidence increases due to damage related diseases, maintains a force of moisturizing the skin exposed to ultra-violet and wrinkle-reducing effect for a long responds by stepwise increasing need for well as main composition are disclosed. On the other hand, play a role in human beneficial lactic acid bacteria such as lactic acid (lactic acid) per carbohydrate as fermenting generating 3339, paper has been found heretofore 400, one of the bracket 18 which is connected to the known. These lactic acid bacteria in particular the immunity, gut immunity enhancing bioactivity on to have a known, recent well-being to apply a, when good food excellent in eating right is likely to social atmosphere to prevent the composition, various cosmetic material developed for traditional culture of lactic acid bacteria is of moisturizing the skin while, for increasing the speed of stratum corneum locking device of (turn over), the mitigating effect reported but wrinkles, chamber number when the cosmetic quality by using inverted triangular screw is removed. In one embodiment, call number would be employed for cosmetic lactic acid with Korean publicized patent number 1991 - 0019600 moisturizing and active oxygen operation which disclosure, Korean publicized patent number 2013 - 0096604 call fermentation cosmetic and its manufacturing method is provided to prepare a sprouted grain fermentation extract as a main component, lactic acid fermentation cultures or cosmetic composition that is created product comprising, like a sprouted grain into the fermentation liquid of the sphingomyelin to the particular lactic acid obtained by the techniques as well as disclosure, disclosure of Korean publicized patent number 2013 - 0115943 call crushing strains of lactic acid bacteria dissolves including anti-inflammatory, skin whitening composition for anti-aging techniques known. However, the desired locus of lactic acid bacteria, such as lyophilized powder is mung beans as well as even number point at the door, door number point associated with stability of lactic acid still remains disclosed. The door number from c acid, lactic acid active ingredient of the present invention is to produce homogeneous number tyndall sterilising body properties article which, for long term custody that a freeze dried to the foothold, cladding or wrinkle skin moisturizing effect of lactic acid bacteria for sterilising tyndall reported bar free. The present invention refers to said elicited to request such as provided, or wrinkle skin moisturizing composition for perform serving as victims of the present invention, lactic acid is the loss of skin moisture by UV radiation sterilising tyndall billion and number or reducing, skin barrier protecting skin moisturizing effect excellent formate, wrinkle formation protein associated with MMP-a 9 expression dose that billion number check, the arrears of work the present invention. In order to achieve said purposes, including non-food tyndall sterilising body lactic acid active ingredient or wrinkle skin moisturizing number under public affairs substrate. In addition, the present invention refers to a cosmetic composition including skin moisturizing or wrinkle tyndall sterilising lactic acid active ingredient number under public affairs substrate. In addition, the present invention refers to a pharmaceutical composition for number tyndall sterilising body including lactic acid active ingredient skin moisturizing or wrinkle under public affairs substrate. The present invention refers to a composition for skin moisturizing or wrinkle tyndall sterilising body including lactic acid active ingredient are disclosed. The present invention according to composition number billion loss of skin moisture induced by UV radiation or reducing effect or wrinkle of moisturizing the skin are disclosed. In addition, the presence of a catalyst composition of the present invention homogeneous properties number each other, the pin is stored for a long time the main. Figure 1 billion result confirming the number of lactic acid sclerite moisture loss quantitytyndall sterilising efficacy are disclosed. * Is compared may be regulated significantly (P<0. 0001); # ultraviolet irradiation compared group which can be significantly (P<0. 0001); the CON regulated; UV ultraviolet irradiation is group; Lactob tyndall sterilising lactic acid is big group of processing. Figure 2 tyndall sterilising lactic acid does not result of skin evaluation are disclosed. * Is compared may be regulated significantly (P<0. 0001); # ultraviolet irradiation compared group which can be significantly (P<0. 0001); the CON regulated; UV ultraviolet irradiation is group; Lactob tyndall sterilising lactic acid is big group of processing. Figure 3 skin wrinkle result through assessing the effectiveness measurement are disclosed. * Is compared may be regulated significantly (P<0. 0001); # ultraviolet irradiation compared group which can be significantly (P<0. 0001); the CON regulated; UV ultraviolet irradiation is group; Lactob tyndall sterilising lactic acid is big group of processing. Figure 4 H&E dyeing wrinkles and assessing the effectiveness of the results of an disclosed. Control normal controls; Vehicle: ultraviolet irradiation controls; Lactob tyndall sterilising lactic acid is big group of processing. Figure 5 result of identifying proteins involved in expression dose tyndall sterilising lactic acid wrinkles are disclosed. The CON regulated; UV ultraviolet irradiation is group; Lactob tyndall sterilising lactic acid is big group of processing. The present invention refers to a non-food tyndall sterilising lactic acid active ingredient or wrinkle skin moisturizing including number under public affairs substrate. Said lactic acid bacteria is Streptococcus ( In addition, lactic acid fermentation process number but not relayed, saccharide yeast extract, peptone SOI and ion component, other growth factor adding a lactic acid bacterium-fermentation preferably. Said locus of lactic acid bacteria in a lactic acid bacterium as tyndall sterilising method, any method which uses known tyndall fulfillment method can be used, for purchasing process from lactic acid number it became widthtyndall sterilising body is used. In a preferred lactic acid fermentation with lactic acid bacteria ferment filtrate after fermentation broth of tyndall separating, 10 to 60 minutes in a lactic ferment 60 to 160 °C heating, in which leads to 20 to 40 °C or 20 °C hereinafter by rapidly cooling a tyndall intermittent sterilization method are disclosed. In addition, lactic acid bacteria in a powdered form lyophilized tyndall said sterilising body preferably does not limited. Included in said skin moisturizing skin moisture loss can be a number or decrease caused by limited billion does not. Health food product of the present invention either adding tyndall sterilising lactic acid can be applied to other food or food component is canceled by the body number bath, according to conventional method appropriately number bath 1308. Said lactic acid may be added as an example of the lollypop sterilising body tyndall food, meat, sausage, bread, chocolate, candy, [su[su] neck type, confectionery, pizza, if, other noodles, gum type, ice cream acid number a dairy product, various sprocket, beverage, difference, drinkable number, alcoholic drinks and vitamin composite number may be selected from the form of either a, health food comprising both in conventional meaning. I.e., said type of food is simplified and a smooth free number. Said various nutritional number health food, vitamin, mineral (electrolyte), synthesis and natural flavor number, colored number and enhancer (cheese, such as chocolate) number, [pheyk[pheyk] The [thu[thu] it buys and salts thereof, the alkyne it buys and salts thereof, organic acid, protective colloidal thickening number, pH control number, stabilizing number, antiseptic number, glycerin, alcohol, number of calcium hydroxide can be used in carbonated beverages and the like. In addition number of natural fruit juice and vegetable beverages containing pulp can be for numerical control machine. The components of the independently or can be used in combination. In addition, health food of the present invention have various flavor number or natural carbohydrate can be like additional active ingredient, said natural the carbohydrate is glucose, such as oligosaccharides monosaccharide, liver, shoe cross and such as disaccharide, and dextrin, polysaccharide such as cyclodextrin, xylitol, sorbitol, such as processes for the preparation of party alcohol[thol[thol] among others. Natural carbohydrate ratio of said large while not significant, health food of the present invention to 100g, 0. 01 - 0. 04g and preferably, more preferably 0. 02 to 0. 03 g including but not limited to. As sweetener number TAU denaturing detergent, such as Stevia extract or natural sweetener number, saccharin, etc. such as synthetic sweetener number oh [su[su] group [lu[lu] with burning, can be. In addition to the lactic acid bacteria of the present invention of said health food product may be tyndall sterilising body skin health related component which can be publicly known. Additional skin health including the health food of the present invention to the original raw material or wrinkle the skin moisturizing effect can be further will prevent, when additional raw material used for skin health, composite used according to skin safety, ease of elder brother anger number, can be consideration of the stability of the efficacy. Said additional skin moisturizing or wrinkle component is the health food of Korea Food and Drug Administration notice circle material or individual qualifying type can be highly from the raw material. Individual qualifying type raw materials such as a composite of said pine tree extract, Ginseng, secretion, whereby mixed extract, finger root extraction powder, N - acetylglucosamine, hyaluronic acid, an extract of an auxiliary device, AP collagen peptide enzymatic degradation, lithospermum erythrorhizon extract powder, such as simple mixed extract, preferably but not limited to peptides. In addition, the present invention refers to a cosmetic composition including skin moisturizing or wrinkle tyndall sterilising lactic acid active ingredient number under public affairs substrate. Said lactic acid bacteria is Streptococcus ( In addition, lactic acid fermentation process number but not relayed, saccharide yeast extract, peptone SOI and ion component, other growth factor adding a lactic acid bacterium-fermentation preferably. Said locus of lactic acid bacteria in a lactic acid bacterium as tyndall sterilising method, any method which uses known tyndall fulfillment method can be used, for purchasing process from lactic acid number it became widthtyndall sterilising body is used. In a preferred lactic acid fermentation with lactic acid bacteria ferment filtrate after fermentation broth of tyndall separating, 10 to 60 minutes in a lactic ferment 60 to 160 °C heating, in which leads to 20 to 40 °C or 20 °C hereinafter by rapidly cooling a tyndall intermittent sterilization method are disclosed. In addition, lactic acid bacteria in a powdered form lyophilized tyndall said sterilising body preferably does not limited. Included in said skin moisturizing skin moisture loss can be a number or decrease caused by limited billion does not. Cosmetic composition of the present invention solution, gel, or paste products solid anhydrous product, water phase dispersed in an oily phase emulsion, suspension, microemulsion, microcapsules, fine granulocyte or liposome-glucose, in the form of a sachet type nonionic dispersion number, cream, skin, lotion, powder, ointment, selected from the group, spray or cone thread stick in the form of ball number can be disclosed. In addition, in the form of a propellant or compressed foam (foam) preferably further contains a number aerosol form of composition as number bath 1308. In addition, lactic acid bacteria in addition to cosmetic composition of the present invention said tyndall sterilising body fatty substances, organic solvent, dissolved number, number and gelling number concentrated, softening number, antioxidant number, number of suspension, stabilizing number, foam (foaming agent) number, direction number, number surfactants, water, -glucose or nonionic emulsion number, charging number, number chelating and sequestering number, preserving number, vitamin, blocking number, number presented, essential oil, dye, pigment, hydrophilic or lipophilic active number, composition based on lipid vesicles or cosmetic component or any other size of less than normally used in the field of cosmetics such as containing auxiliary number can be. The active ingredient of the present invention tyndall sterilising body including lactic acid or wrinkle skin moisturizing cosmetic composition, a cosmetic composition of the present invention is typically contained for tyndall sterilising lactic acid 0. 01 to 15 weight %, preferably 2 to 10% by weight can be solids content of the coating. In addition to the lactic acid bacteria of the present invention said cosmetic composition for skin moisturizing or wrinkle tyndall publicly known or wrinkle skin moisturizing of sterilising body can for a component. Additional to the original raw material including the surface skin health, or wrinkle cosmetic composition of the present invention skin moisturizing effect can be further will prevent, at the time of skin health to the original raw material for composite yarn according to additional skin safety, ease of elder brother anger number, can be consideration of the stability of the efficacy. In addition, the present invention refers to a pharmaceutical composition for number tyndall sterilising body including lactic acid active ingredient skin moisturizing or wrinkle under public affairs substrate. Said lactic acid bacteria is Streptococcus ( In addition, lactic acid fermentation process number but not relayed, saccharide yeast extract, peptone SOI and ion component, other growth factor adding a lactic acid bacterium-fermentation preferably. Said locus of lactic acid bacteria in a lactic acid bacterium as tyndall sterilising method, any method which uses known tyndall fulfillment method can be used, for purchasing process from lactic acid number it became widthtyndall sterilising body is used. In a preferred lactic acid fermentation with lactic acid bacteria ferment filtrate after fermentation broth of tyndall separating, 10 to 60 minutes in a lactic ferment 60 to 160 °C heating, in which leads to 20 to 40 °C or 20 °C hereinafter by rapidly cooling a tyndall intermittent sterilization method are disclosed. In addition, lactic acid bacteria in a powdered form lyophilized tyndall said sterilising body preferably does not limited. In addition to the active of the present invention pharmaceutical compositions administration described in addition to said at least one pharmaceutically acceptable carrier including number 1 can be high pressure liquid coolant. The heater of the present invention which carrier comprises a pharmaceutically acceptable ingredient compatible and must, saline, sterile water, ringer's solution, buffer saline, lactose dextran solution, maltodextrin solution, glycerol, ethanol and of these components can be mixed at least 1 component, antioxidant number needed, buffer, addition of other usual number such as bacteriostatic number can be added. In addition, dilution number, dispersion number, number surfactants, number and lubrication number added coupled added to aqueous solution, suspension, emulsion for injection number number number under anger-such as can be. In addition, acid number, positive number, number capsule, liquid number, scan number, number ointment, syrup can be in various forms such as number number number under anger - dose or disclosed - unit dose container, for example sealed ampoule glass bottle and the like ball number can also be disclosed. Pharmaceutical compositions unexpectedly give rise permits oral or parenteral administration of the present invention. The present invention according to these routes but not confined within the pharmaceutical composition, for example, oral, intravenous, intramuscular, in artery, intramedullary, in epidural, intracardiac, transdermal, subcutaneous, intraperitoneally, Minister, sublingual or topical administration permits. The pharmaceutical compositions unexpectedly give rise publicly known clinical administration to an appropriate number of the present invention can be used technique of under anger-number number. Body weight of patients doses of the present invention composition, age, sex, health condition, dietary, administration time, method, according to the printed wiring board with a variety of diseases and to rate the severity and range, conventional art hereinafter for expert can determine. Hereinafter, the present invention broadcast receiver using more detailed in the embodiment. In the embodiment of the present invention is more specifically describe the present invention only these for the number one is a person with skill in the art that these range by not notified to the reduced in the art are disclosed. [Material and method] Preparation of lactic acid tyndall sterilising body: of stock of Lactobacillus ( [Effective and sample administration] The new variety of new resin 7 male mouse (male HR provided 1, Hairless mice, Japan SLC inc.) purchased from central effective week zero 1 after adapting as well as during the main. The general condition during an adaptation period are observed to animal testing as well as healthy state. Breeding environment is 23 ± 3 °C temperature, humidity 50 ± 5%, contrast period 12 time (07:00 - 19:00/illumination time) was maintained. The embryo during effective military North Korean Workers Party 7 have fed between tester, 5L 79 when the dedicated mouse feed (Charles river, USA) free machine for livestock feed, water glass disinfecting constant readings was free machine for livestock. Sample administration controls (control), group with UV radiation (UV), lactic acid (Lactob) total 3 divided into two tyndall sterilising body administration group the group consisting of morphine. Sample administration oral administration using his mouse treatment with respect embodiment. The total dosing period 12 mainly during main 5 was administered. [Ultraviolet irradiation] 12 main 3 times during population number external grudge-capturing ultraviolet irradiation experiments have main kind of embodiment, a UVB ultraviolet lamp (Mineralight UV Display lamp, UVP, USA) was used. The ultraviolet irradiation and 1 to 7 the daytime 60mJ/cm2, 8 to 12 to which main 12 90mJ/cm2 during visit from the police. The storehouse meter using ultraviolet irradiation (Delta OHM, Italy) by measuring the amount of light illumination times can be regulated. [Moisturizing assessing the efficacy] 1) sclerite moisture loss quantity (TEWL: transepidermal water loss) evaluation Further sclerite moisture evaporation amount, polyolefin conditions (23 °C, relative humidity 50%) (Tewameter Courage & Khazaka, Germany) in [thwu[thwu] and meter utilizing a calculated amount of moisture evaporation in skin area and over time, reads electronic sensor (g/m2/hr) humectant amount of moisture evaporation, a plurality of same force of moisturizing the skin were measured. 2) measuring skin water content The air conditioner does not skin conditions (23 °C, relative humidity 50%) (Corneometer Courage & Khazaka, Germany) receives the nose [ni[ni] in skin equipment are located were measured. Present in the amount of moisture of the skin relief ion level for moisture sensor, a plurality of vacuum force by calculation of the same amount of moisture were measured. [Skin histological observation] 10% neutral formalin-fixed resin mixed with an aqueous solution such as new skin tissue and the conventional method after washing, dehydration, transparent, then to 4 m and then formed in a thickness produced fragment penetration process paraffin tissue dyeing (Hematoxylin & Eosin; H&E) was a micro embodiment. [Electrophoretic and Western blotting] 20 to 30 mg out skin tissue using proteins selected from the, reservoir and to isolate the proteins, matching opening the same amount of protein (actin) moved from PVDF membrane by reacting protein expression dose after electrophoretic antibodies were measured. [Statistical method] The result obtained in the present invention one a-way ANOVA using controls and significance between experiments on Student t-a test group was assay (p<0. 05). In the embodiment 1. tyndall Lactic acid Sterilising bodyProcessing group Assessing the efficacy moisturizing 1) transdermal water loss amounts (TEWL: transepidermal water loss) analysis For each experimental group in skin moisturizing effects such as a new embodiment analysis was separated transdermal water loss amounts. Transdermal water loss amounts displayed in the emitted from the skin as a water amount, the higher the return electrode and regenerating skin moisturizing function is constructed, exhibits unique barrier function of skin has been damaged. The automatic transdermal water inlet pipe, polyolefin conditions (23 °C, relative humidity: 50%) [thwu[thwu] and meter (Tewameter Courage & Khazaka, Germany) in the amount of moisture evaporation in skin area and when the calculated time, evaporation amount of moisture (g/m2 /Hr) humectant reads electronic sensor, a plurality of same force of moisturizing the skin were measured. Also shown to result 1. Such as also 1, skin barrier by UV radiation to form skin moisturizing function which are not inserted cream (p<0. 0001), lactic acid (Lactob) tyndall skin moisture loss caused by ultraviolet radiation by the kind of the processing sterilising body strongly absorbing significance has been confirmed (p<0. 0001). 2) measuring skin water content Skin such as a new group for each experiment measures the amount of moisture contained separated embodiment does not result in skin skin analysis, such as ultraviolet irradiation in Figure 2 identifying the moisture amount of the skin is reduced compared to a group of regulated schedulable have (p<0. 0001), ultraviolet irradiation compared to its high moisture content and the attached group tyndall sterilising lactic acid group appeared. This result has been confirmed that the skin moisturizing effect to the second tyndall attached sterilising lactic acid based on the light into electricity. In the embodiment 2. Assessing the efficacy by thickness variations in the skin Efficacy has been confirmed through skin wrinkles billion number measurement. Skin thickness H&E dyeing embodiment texture in the stratum corneum (keratin layer) epidermal basement membrane thickness (epidermal basement membrane) were measured using a microscope mounted to bath. The disclosure herein also 3 result, ultraviolet investigation at the time of can confirm that increased epidermal thickness value, lactic acid administration reduces the thickness skin by identifying capable of schedulable tyndall sterilising body kind. In the embodiment 3. (H&E dyeing) assessing the efficacy by tissue dyeing UV-induced mouse skin tissue in order to identify new efficacy corrugation billion number stripped even through a tissue after dyeing has been confirmed. The disclosure also 4 as ultraviolet irradiation compared to controls a group of activated stratum corneum occurs, and to selectively confirming the increased epidermal thickness in addition, ultraviolet irradiation from the group consisting of lactic acid bacteria administration group not ultraviolet irradiation tyndalltyndall sterilising body relaxed as compared to administration of sterilising lactic acid group characterized in that it has the stratum corneum, epidermal thickness in addition is also used for capable of reducing. In the embodiment 4. MMP-9 (matrix Metallopeptidase 9) protein expression quantity evaluating Wrinkle formation known as MMP-a 9 protein plays an important role (matrix metallopeptidase 9) measured expression dose, the disclosure also 5 as, ultraviolet irradiation (UV) compared to the group without applying the test group (Con) protein expression dose has been increased formate, the sterilising lactic acid treated included in a test group (Lactob) compared to the enzyme expressed by the MMP-a 9 protein expression dose reduced. Said determiner determines whether the result was effective for wrinkle caused by ultraviolet light. Number attainments 1. tyndall Lactic acid A sterilising Including skin moisturizing or active ingredient Number of bath cosmetic 1) number of flexible skin water bath The active ingredient of the present invention including a flexible skin tyndall sterilising lactic acid number was high pressure liquid coolant. Lactic acid tyndall sterilising body 10. 00 parts by weight, 1, 3 - butylene glycol 1. 00 parts by weight, d small [tyum[tyum] this D mote A 0. 05 parts by weight, 0 output device is examined. 10 parts by weight, other [syum[syum] writing hour deposit number light 0. 05 parts by weight, sheet [lik[lik] Child seed [tu[tu] 0. 01 parts by weight, sodium citrate 0. 02 parts by weight, writing three [ley[ley] -26 1. 00 parts by weight, arbutin 2. 00 parts by weight, number hydrogel four motethe [tu[tu] it digs up, stub oil 1. 00 parts by weight, ethanol 30. 00 parts by weight, preservation number, colored number and flavour trace number, consisting of a high pressure liquid coolant be trillion expense positive number number number of maleic anhydride was manufactured. 2) number of encapsulated into bath tyndall sterilising body as an active ingredient of the present invention lactic acid nutritional cream number was high pressure liquid coolant. Lactic acid tyndall sterilising body 10. 0 parts by weight; 1, 3 - butylene glycol 7. 0 parts by weight; glycerin 1. 0 parts by weight; petal reel glow D - 0. 1 parts by weight; plant extract 3. 2 parts by weight; magnesium aluminum utilitarian Kate 0. 3 parts by weight; PEG provided 40 stearate 1. 2 parts by weight; [su[su] reel Oh [lik[lik] child seed [tu[tu] 2. 0 parts by weight; 60 1 2 polysorbates. 5 parts by weight; the type writing three reel [su[su] reel which it hits Oh the [ley[ley] the [thu[thu] 2. 0 parts by weight; sorbitol the grief three [su[su] ear a [thu[thu] which comes 1. 5 parts by weight; three reels biting alcohol 3. 0 parts by weight; it carries on shoulder with the oil 4. 0 parts by weight; [su[su] egg column 3. 8 parts by weight; reel [lik[lik][lik[lik] Tree oyster Scherrer id capric acid/carboxylic acid 2. 8 parts by weight; vegetable oil 1. 8 parts by weight ;-in-0. 4 parts by weight; other [syum[syum] writing tax collector deposit number light trace; alane is examined to trace; sodium oh in base four [thu[thu] trace; tocopheryl acetate returned; high pressure returned; preservation number returned; flavour number returned; and a positive and number of maleic anhydride trillion expense nutrient cream number number be made his high pressure liquid coolant. 3) number of bath selected from the group According to a composition ratio, lactic acid tyndall sterilising body, be positive number, butylated, high egg base theory it buys extract, glycerin metering in the mixing 80 ± 2 °C, water (water phase) the arrears of work. In addition, profile para, lecithin, the oily phase (oil phase) oil metering 80 ± 2 °C maca day E[...] to mixing the arrears of work. Said oily phase after phase two phases (phase) while adding to make a mixture of emulsion is disclosed, said perfume mixture selected from the group including a high pressure liquid coolant to the cooling tyndall adding lactic acid number was 35 ± 2 °C sterilising body. Lactic acid water ingredient tyndall sterilising body 8. 00 parts by weight; be positive number 7. 58 parts by weight; butylated 0. 15 parts by weight; high egg base theory it buys extract 2. 50 parts by weight; glycerin 8. 00 parts by weight of a number adapted to trillion expense. Oily ingredient profile butylated 0. 10 parts by weight; lecithin 0. 60 parts by weight; e car missing child[...] oil 10. 0 parts by weight; and additive number to perfume 0. 07 parts by weight of a number adapted to trillion expense. Number attainments 2. tyndall Lactic acid A sterilising Skin moisturizing and main active ingredientHealth food roentgen per hour at one meter improvement number bath 1) flour food number bath 0 lactic acid bacteria of the present invention tyndall sterilising body. 5 - 5. 0 parts by weight of followed by addition of flour, is by using mixture of bread, cake, cookie, a cracker and noodles in the number was high pressure liquid coolant. 2) oil number article (dairy products) number of bath 5 - 10 parts by weight of a lactic acid bacteria of the present invention followed by addition of milk tyndall sterilising body, said high pressure liquid coolant using various areas such as ice cream and butter milk wire number number his article. 3) number persimmon bath Brown rice, barley, glutinous rice, a publicly known method of drying the liquid flavoring destruct after 60 meshes the pregelatinized powder was high pressure liquid coolant number particle size distribution. Adult, assay sesame, publicly known method of particle size distribution in the range of 0.1 after drying as perilla also flavoring number 60 meshes powder was high pressure liquid coolant. A lactic acid bacteria of the present invention vacuum concentrator pressure concentrated tyndall sterilising, spray, heated-air dryer to dry flavoring agents obtained in the plane of the mesh particle size 60 manufactured dry powder are obtained. In said high pressure liquid coolant manufacture number, bell room current, and high pressure liquid coolant to the next body increases his number tyndall sterilising lactic acid. Heighten (30 parts by weight of brown rice, 15 parts by weight of destruct, 20 parts by weight of barley); (perilla 7 parts by weight, 8 parts by weight of adult, assay sesame 7 parts by weight) bell room current: tyndall sterilising body lactic acid (3 parts by weight); ganoderma lucidum (0. 5 parts by weight); new (0. 5 parts by weight) 4) number of the chocolate bath Drugs butter 30. 0 parts by weight; milk powder 30. 0 parts by weight; 41 per minute. 85 parts by weight; lecithin 0. 45 parts by weight; perfume 0. 1 parts by weight; tyndall sterilising body lactic acid 0. 6 parts by weight of one selected from a number trillion expense, including a chocolate tyndall sterilising lactic acid number was high pressure liquid coolant. 5) number of health beverage tank Liquid processes (0. 5%), oligosaccharide (2%), sugar (2%), salt (0. 5%), water (75%) of the present invention such as foods containing lactic acid lubricant after sterilisation tyndall sterilising body 5g and momentarily to a homogenizer, and vial, container enclosing a number such as one time use his gear high pressure liquid coolant. 6) vegetable juice number bath A lactic acid bacteria of the present invention applied to a high pressure liquid coolant vegetable juices carrot juice 1,000 ml tyndall sterilising body 5g making his number. 7) number of bath fruit juice A lactic acid bacteria of the present invention applied to a high pressure liquid coolant grape juices tyndall sterilising body 1g 1,000 ml apple or fruit juice his number. The present invention relates to a skin-moisturizing or anti-wrinkle composition including dead cells of tyndalized lactic acid bacteria as an effective component. The effect of dead cells of tyndalized lactic acid bacteria on the moisturizing and wrinkle-mitigating of skin, which has been degraded by ultraviolet radiation, was confirmed. As a result, it was confirmed that the amount of moisture evaporating from the skin was reduced and the amount of moisture contained in the skin was increased. In addition, it was confirmed that the epidermal thickness was reduced and the expression levels of wrinkle-related proteins were reduced. Therefore, the composition according to the present invention mitigates damage to skin barriers, which is caused by ultraviolet radiation, thereby suppressing the loss of skin moisture or wrinkle formation. Lactobacillus tyndall of stock ( According to Claim 1, relative to the weight of the total weight of said cosmetic composition of stock of Lactobacillus tyndall sterilising body 0. 01 - 15% by weight compound having at least one cosmetic composition characterized skin moisturizing and wrinkle. According to Claim 1, Lactobacillus fermentation with lactic acid bacteria ferment filtrate after separating said tyndall sterilising body of stock, of stock of 10 - 60 minutes in a Lactobacillus ferment 60 provided 160 °C heating, 20 provided 40 °C or 20 °C hereinafter characterized by rapidly cooling method which leads to skin moisturizing and wrinkle cosmetic composition prepared by the number. According to Claim 1, characterized in that said polyester tyndall sterilising body lyophilized powder form of stock of skin moisturizing and wrinkle cosmetic composition. According to Claim 1, said skin moisturizing skin moisture loss by UV radiation is characterized by skin moisturizing and wrinkle reduction billion number or cosmetic composition. According to Claim 1, said cosmetic composition fatty substance, organic solvent, dissolved number, number and gelling number concentrated, softening number, antioxidant number, number of suspension, stabilizing number, foam (foaming agent) number, direction number, number surfactants, water, -glucose or nonionic emulsion number, charging number, number chelating and sequestering number, preserving number, vitamin, blocking number, number presented, essential oil, dye, pigment, hydrophilic or lipophilic active number, characterized in further including at least one auxiliary number selected composition based on lipid vesicles skin moisturizing and wrinkle cosmetic composition. According to one of Claim 1 to Claim 6, said cosmetic composition solution, gel, or paste products solid anhydrous product, water phase dispersed in an oily phase emulsion, suspension, microemulsion, microcapsules, fine granulocyte or liposome-glucose, in the form of a sachet type nonionic dispersion number, cream, skin, lotion, powder, ointment, selected from the group, spray or cone thread characterized one of number selected from stick-skin moisturizing and wrinkle cosmetic composition. Lactobacillus tyndall of stock ( According to Claim 8, Lactobacillus fermentation with lactic acid bacteria ferment filtrate after separating said tyndall sterilising body of stock, of stock of 10 - 60 minutes in a Lactobacillus ferment 60 provided 160 °C heating, 20 provided 40 °C or 20 °C hereinafter characterized by rapidly cooling method which leads to skin moisturizing and wrinkle-reducing pharmaceutical composition prepared by the number.
