VACCINE COMPOSITION FOR PREVENTING STAPHYLOCOCCUS AUREUS INFECTION
14-11-2013 дата публикации
Номер:
WO2013168965A2
Автор: LEE, Bok Luel, KENJI, Kurokawa, JUNG, Dong-Jun, AN, Jang-Hyun, JEON, Yu-Jin, KIM, Na Hyang, KAZUE, Takahashi, KIM, Eunmi, AHN, Dong Ho
Принадлежит: 목암생명공학연구소, 부산대학교 산학협력단
Контакты:
Номер заявки: KR39-00-201357
Дата заявки: 07-05-2013
The present invention relates to a vaccine composition for preventing staphylococcus aureus infection containing, as an active ingredient, a ribitol-phosphate which has been modified only by a β-configuration in N-Acetylglucosamine (GlcNAc), a repeating unit of the ribitol-phosphate, or a wall teichoic acid (WTA) containing the repeating unit. The composition according to the present invention contains a coupling motif (an epitope) for an anti-WTA antibody, and thus can be effectively used as a vaccine composition or to prevent staphylococcus aureus infection by generating anti-WTA antibody.[0000][1]