Процессор для обработки данных электропроводности кожи и устройство для обнаружения по меньшей мере одной стадии синдрома выгорания и/или синдрома хронической усталости живого существа

Группа изобретений относится к медицине. Способ обработки данных осуществляют с помощью устройства для обнаружения стадий стрессового состояния живого существа. Устройство содержит измерительный блок для измерения данных электропроводности кожи за промежуток времени и процессор (10) для обработки данных электропроводности кожи живого существа. Процессор содержит блок (12) ввода для приема сигнала (13) данных электропроводности кожи, содержащего пиковые данные, вычислительный блок (14) и анализирующий блок (16). Вычислительный блок (14) осуществляет вычисление сигнала данных пиковых значений электропроводности кожи за день путем получения характеристики, связанной с указанными пиками данных, и формирования суммы значений указанной характеристики за единицу времени. Анализирующий блок (16) анализирует среднее значение и/или абсолютное значение сигнала данных пиковых значений электропроводности кожи за часть указанного периода времени для получения информации о стадии стрессового состояния ...

ЧУВСТВИТЕЛЬНЫЙ К ДАВЛЕНИЮ ЗОНД С ВЫСОКОЙ ЧУВСТВИТЕЛЬНОСТЬЮ

... 1. Медицинский зонд, содержащий: ! вводимую трубку, имеющую продольную ось и имеющую дистальный конец; ! дистальный кончик, который расположен на дистальном конце вводимой трубки и сконфигурирован для введения в контакт с тканью тела; ! стык, который соединяет дистальный кончик с дистальным концом вводимой трубки; и ! датчик стыка, заключенный внутри зонда, для распознавания положения дистального кончика относительно дистального конца вводимой трубки, причем датчик стыка содержит первый и второй подузлы, которые расположены внутри зонда на противоположных соответствующих сторонах стыка, и каждый подузел содержит один или более магнитных измерительных преобразователей. ! 2. Зонд по п.1, в котором магнитный измерительный преобразователь содержит катушки, и где первый подузел содержит первую катушку, имеющую ось первой катушки, параллельную продольной оси вводимой трубки, и где второй подузел содержит две или более вторых катушек в разных соответствующих радиальных местоположениях в пределах ...

Optischer Kraftsensor

Optischer Kraftsensor mit (a) einem Verformungskörper (30), (b) einem Lichtwellenleiter (26), (c) einem Reflektor (36), der so am Verformungskörper (30) angeordnet ist, dass ein aus dem Lichtwellenleiter (26) kommender Lichtstrahl (38) reflektiert wird und eine auf dem Verformungskörper (30) wirkende Messkraft (F ) oder ein Moment (M ) zu einer Bewegung des Reflektors (36) führt, (d) wobei der Lichtwellenleiter (26) angeordnet ist zum Leiten eines multichromatischen Lichtstrahls (38) auf den Reflektor (36), so dass ein reflektierter Lichtstrahl (42) entsteht, der zumindest teilweise in den Lichtwellenleiter (26) zurückläuft, so dass der reflektierte Lichtstrahl (42) zu einem Messausgang des Lichtwellenleiters (26) leitbar ist, und (e) einem optischen Element (40), das eine chromatische Aberration bewirkt und so angeordnet ist, dass vom Lichtwellenleiter (26) kommendes Licht so auf den Reflektor (36) fokussiert wird, dass sich ein Spektrum (24) des reflektierten Lichtstrahls (42) am Messausgang ...

Digestive profiling system

REGULATABLE INTRAORAL MANDIBULAR ADVANCEMENT DEVICE, FOR PREVENTING SNORING AND SLEEP APNOEA

The invention relates to a regulatable intraoral mandibular advancement device that can be used to prevent snoring and sleep apnoea. Said device comprises two splints connected by a central screw (1) inserted into a sheath (2) comprising an upper ring (3), said sheath being used as a guiding housing (4) for an upper bar (5) of an upper plate (6), and the lower part of the sheath comprising a longitudinal groove (8) enabling the course of an inner mobile threaded (10) ring (9) that is displaced by the screw (1), and on which a lower displacement ring (11) is arranged, open or closed, said ring being provided with a perpendicular hole (12) with elipsoidal conicity, in which the lower bar (13) fixed to the lower maxillary plate (14) is inserted. Said screw (1) is locked to the sheath (2) on its rear part.

The invention relates to a method for broadcasting by a watch an information message relating to an assessment of the quality of life of a wearer of said watch.

L'invention concerne un procédé de diffusion par une montre d'un message informatif relatif à une évaluation de la qualité de vie d'un porteur de ladite montre, le procédé comportant les étapes suivantes : enregistrement (10) par une unité de traitement de données descriptives d'au moins un épisode événementiel d'au moins un type d'événement environnemental relevé durant une période déterminée ; identification (11) d'au moins un type d'événement environnemental perturbateur de la qualité de vie du porteur à partir d'un traitement desdites données descriptives ; estimation (16) d'un indice d'évaluation de la qualité de vie du porteur en fonction d'un indicateur de perturbation de la qualité de vie relatif à chaque type d'événement environnemental perturbateur de la qualité de vie identifié, et conception (17) du message informatif comprenant l'indice d'évaluation estimé en prévision de sa diffusion à destination du porteur.

ФАРМАЦЕВТИЧЕСКАЯ ЛЕКАРСТВЕННАЯ ФОРМА ДЛЯ НЕМЕДЛЕННОГО ВЫСВОБОЖДЕНИЯ ПРОИЗВОДНОГО ИНДОЛИНОНА

В заявке описана фармацевтическая лекарственная форма для доставки с немедленным профилем высвобождения, содержащая активное вещество моноэтансульфонат 3-Z-[1-(4-(N-((4-метилпиперазин-1-ил)метилкарбонил)-N-метиламино)анилино)-1-фенилметилен]-6-метоксикарбонил-2-индолинона.

PHARMACEUTICAL DOSAGE FORM FOR IMMEDIATE RELEASE OF AN INDOLINONE DERIVATIVE

Device for preventing myopia and cervical spondylosis

The invention discloses a device for preventing myopia and cervical spondylosis, which comprises a data acquisition module (1), a main control module (2), a warning module (3) and a power module (4), wherein the data acquisition module (1) is connected with the main control module (2); the main control module (2) is connected with the warning module (3); the power module (4) is used for supplying power and managing charging for the device; each module receives and sends data or instructions through a data bus; and the main control module (2) determines the using state of a user by processing the data acquired by the acquisition module and the dependence and training data of a posture and motion decision tree algorithm. The device determines whether to give a warning or not by performing logic operation on different configurable standard data and the acquired data in different using states. The device not only can judge the using state of the user, but also adjusts the standard parameter ...

SYSTEM FOR PROVIDING SUBJECT-INDEPENDENT BRAIN-COMPUTER INTERFACE AND METHOD THEREOF

Body Balance Measuring System

MONITORING THE USE OF LANGUAGE OF A PATIENT FOR IDENTIFYING POTENTIAL SPEECH AND RELATED NEUROLOGICAL DISORDERS

A method and associated computer system and computer program product for monitoring the use of language of a patient that may enable the identification, analysis and reporting on of the natural progression of various neurological or speech disorders, is provided. The method includes obtaining a verbal response of the patient to a stimulus, converting the verbal response into text and the generating of verbal and textual response data by analyzing the verbal response and response text, respectively. A response vector may be formed base on the verbal and textual response data, which may then be used to determine a reply to the patient. Improved accuracy and consistency of monitoring the use of language associated with neurological and speech disorders is achieved, leading to a greater rate of success in the treatment of these conditions.

РЕГУЛИРУЕМОЕ ВНУТРИРОТОВОЕ УСТРОЙСТВО ВЫДВИЖЕНИЯ НИЖНЕЙ ЧЕЛЮСТИ ВПЕРЕД ДЛЯ ПРЕДОТВРАЩЕНИЯ ХРАПА И АПНОЭ СНА

Изобретение относится к области медицинской техники и может использоваться для предотвращения храпа и апноэ сна. Внутриротовое регулируемое устройство выдвижения нижней челюсти вперед для предотвращения храпа и апноэ сна состоит из соединенных шин или пластин, повторяющих форму челюстей пациента. Устройство содержит винт, расположенный в полигональном цилиндрическом корпусе, в передней части которого имеется верхнее подвижное кольцо, разомкнутое или сомкнутое и сужающееся к центру, выступающее в качестве направляющей для верхней штанги, прикрепленной к верхнечелюстной пластине. В нижней части корпуса выполнена продольная канавка, обеспечивающая перемещение внутреннего подвижного кольца с резьбой, которое соединено с и перемещается винтом и на котором расположено нижнее подвижное разомкнутое или сомкнутое кольцо, в котором имеется перпендикулярное отверстие в форме эллиптического конуса, в которое вставляется нижняя штанга, прикрепленная к нижнечелюстной пластине. Вышеуказанный винт фиксируется ...

GERUCHSSENSOR

Regulatable intraoral mandibular advancement device, for preventing snoring and sleep apnoea

The invention relates to a regulatable intraoral mandibular advancement device that can be used to prevent snoring and sleep apnoea. Said device comprises two splints connected by a central screw (1) inserted into a sheath (2) comprising an upper ring (3), said sheath being used as a guiding housing (4) for an upper bar (5) of an upper plate (6), and the lower part of the sheath comprising a longitudinal groove (8) enabling the course of an inner mobile threaded (10) ring (9) that is displaced by the screw (1), and on which a lower displacement ring (11) is arranged, open or closed, said ring being provided with a perpendicular hole (12) with elipsoidal conicity, in which the lower bar (13) fixed to the lower maxillary plate (14) is inserted. Said screw (1) is locked to the sheath (2) on its rear part.

Plurality of lamination for soft tissue compression support, protection and bracing intelligent textile for equine and equestrian sports or activities

Described here is a plurality of laminations and elements for constructing an improved Equestrian soft tissue compression support and intelligent textile for Equine, Equestrian Sports or Activities including but not limited to bracing. Scientific research and testing cites the inherent flaws to Prior Art which may make them undesirable to use. Prior Art has been shown to introduce allergies, heat damage, mechanical injuries and joint interference from material binding, bunching and migrating. Due to inherent flaws of Prior Art, they are not suitable for the plurality of laminations and elements to include fibertronics; organic electronics and other forms of e- textiles. Intelligent textiles can aid in expanding the working knowledge of equine or human sports related, repetitive use, occupational and mechanical injuries, rehabilitation treatment and prevention. The intelligent textile pertains generally to monitoring of joint and soft tissues that support a joint of a human or animal body ...

DETECTION OF NUTRIENT DEFICIENCIES INFLUENCING OCULAR HEALTH

The present invention provides methods for identifying and treating subjects having nutrient deficiencies. A method for scoring nutritional deficiency in a subject's eye is also provided.

METHOD FOR INTEGRATED SIGNAL PROCESSING OF BCI SYSTEM

Pharmaceutical dosage form for immediate release of an indolinone derivative

The present invention relates to a pharmaceutical dosage form delivering an immediate release profile containing the active substance 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)- methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbony1-2-in dolinone-monoethanesulphonate.

DEVICE FOR PREVENTING MYOPIA AND CERVICAL SPONDYLOSIS

Disclosed is a device for preventing myopia and cervical spondylosis, comprising a data acquisition module (1), a main control module (2), a warning module (3) and a power module (4). The data acquisition module (1) is connected to the main control module (2), the main control module (2) is connected to the warning module (3), and the power module (4) provides the power supply and charge management. Each module receives and transmits data or instructions via a data bus. The main control module (2) processes the data acquired by the data acquisition module (1) and the dependence and training data of an attitude and motion decision tree algorithm to determine the usage state of a user. A logic operation is performed, according to different configurable standard data under different usage states and acquired data, to determine whether to give an alarm. The device for preventing myopia and cervical spondylosis can judge the usage state of a user, regulates standard parameters, which an alarm ...

DEVICE AND METHOD TO DETERMINE OBJECTIVELY VISUAL MEMORY OF IMAGES

Apparatus, system, and computer readable media determine the probability of visual recognition of an image by a subject using electroencephalography (EEG) corresponding to a Visual Evoked Potential (VEP). The apparatus comprises means for presenting a series of visual stimuli corresponding to said image to evoke EEG signals. The visual stimuli of the image are presented in an orientation sequence based on a timing cycle. At least one prism is provided for placement in front of the series of visual stimuli corresponding to said image. The EEG signals evoked in response to said visual stimuli and said prism placed in front of said visual stimuli are recorded and processed by a processor. VEP is generated corresponding to the presence of a shift and thereby provides object statistic reliability of the visual recognition of the image by the subject.

Particle beam therapy system

The objective is to eliminate the effect of the hysteresis of a scanning electromagnet and resume high-accuracy beam irradiation from an irradiation position where it has been interrupted, even in the case where emergency-stop processing is performed during therapy. There are provided an irradiation management apparatus that controls a scanning electromagnet; and an interlock information inputting device that generates an interlock signal for stopping irradiation of the charged particle beam, when a contingency occurs. When irradiation of the charged particle beam is resumed, the irradiation management apparatus performs idle operation in which the scanning electromagnet is controlled, with the charged particle beam unirradiated, from a start step, which is situated prior to a stop step and is different from the initial step in actual irradiation, to the stop step, and then irradiates the charged particle beam from the desired irradiation position coordinates corresponding to the stop step ...

Способ и система для многопараметрической оценки влияния погоды, магнитного поля Земли и состояния воздуха на функционирование различных систем организма человека

Группа изобретений относится к медицине и может быть использована для прогнозирования состояния человека в зависимости от параметров окружающей среды. Группа изобретений представлена способом и системой многопараметрической оценки влияния параметров окружающей среды на функционирование систем организма человека. Пользователь компьютерного устройства (2) задает личные данные, геолокацию. Передают указанные данные в процессорный блок (4). Осуществляется запрос процессорным блоком (4) прогнозных данных об окружающей среде: прогноз погоды, прогноз геомагнитного фона и прогноз состояния воздуха в соответствии с геолокацией у метеосервера (5). Метеосервер (5) передает прогнозные данных в процессорный блок (4). Передают данные пользователя и прогнозные данные в шифратор (8). Формируют единый хеш-код, содержащий данные пользователя и прогнозные данные. Передают хеш-код в дешифратор (9) и его сопоставляют с базой данных (10) зависимостей функционирования систем организма человека от параметров погоды ...

Verfahren zur Feststellung der Händigkeit

Das Verfahren kann in zwei Ausführungsvarianten umgesetzt werden, wobei im ersten Ausführungsbeispiel bestimmt wird, mit welcher Körperseite eine Person mehr Tastenanschläge auf einem oder mehreren Tastengeräten erzielt. In dem Verfahren werden Tippbewegungen aufgezeichnet, die eine Person mit Fingern, Händen und/oder Füßen durchführt, indem Tasten auf einer Tastatur, zwei Handtastengerät und einem Doppel-Fußtastengerät gedrückt werden. Die Tastenanschläge sollen gemäß vorgegebener Muster in einer bestimmten Reihenfolge durchgeführt werden. Das Tippen wird mittels eines Computers sowie eines geeigneten Softwareprogrammes erfasst und ausgewertet. Bei der Auswertung werden die gemäß den vorgegebenen Mustern korrekten Tastenanschläge sowie die gemachten Fehler ausgezählt. Zur Bestimmung einer motorisch dominanten Körperseite einer Person werden die Ergebnisse (Anzahl der korrekten Tastenanschläge und Anzahl der fehlerhaften Anschläge) je Körperseite getrennt erfasst, gegenübergestellt sowie ...

Method and system for selecting inhaler

SMELL SENSOR

Regulatable intraoral mandibular advancement device, for preventing snoring and sleep apnoea

The invention relates to a regulatable intraoral mandibular advancement device that can be used to prevent snoring and sleep apnoea. Said device comprises two splints connected by a central screw (1) inserted into a sheath (2) comprising an upper ring (3), said sheath being used as a guiding housing (4) for an upper bar (5) of an upper plate (6), and the lower part of the sheath comprising a longitudinal groove (8) enabling the course of an inner mobile threaded (10) ring (9) that is displaced by the screw (1), and on which a lower displacement ring (11) is arranged, open or closed, said ring being provided with a perpendicular hole (12) with elipsoidal conicity, in which the lower bar (13) fixed to the lower maxillary plate (14) is inserted. Said screw (1) is locked to the sheath (2) on its rear part.

Organism data processing method and device, storage medium and program

Provided is an organism data processing method and device, storage medium and program that is able to predict and control changes in the state of an organism. The level of expression of molecules in an organism is measured over a set time interval; the measured time-series data is divided into a periodic component, an environmental stimulus response component and a baseline component; a constant region of the time-series data is identified from variations in the baseline component or from the amplitude or periodic variations of the periodic component; and causal relationships within the identified constant region are identified. The relationship between the external environment and variations in the internal environment is identified and from the causal relationships within the identified constant region, changes in the state of the organism are inferred. Further, from the relationship between the external environment and variations in the internal environment, inferring disease onset in ...

SYSTEM AND METHOD FOR MEASURING BODY CHANGE ACCORDING TO PRESENTATION OF STIMULATION FOR CLASSIFICATION OF SEX CRIMES

Disclosed are a system and a method for measuring a body change according to presentation of stimulation for classification of sex crimes. According to the present invention, sensors of an apparatus for measuring a body change for classification of sexual crimes are attached to the body of a subject. A penis diameter change measuring unit, an electrocardiogram measuring unit, and various sensors (for example, skin conductivity detecting unit, skin conduction and visual deviation detecting unit, safety measuring circuit) for measuring psycho physiological reactions are attached, wherein the penis diameter change measuring unit uses a strain gauge which measures a change amount in the diameter of a penis of a subject according to auditory stimulation and visual stimulation of presenting pictures of children or adults by imitating a virtual sexual situation. Measured biosignals are transmitted to a computer, and the type and stimulation source database of sex offenders are constructed. In ...

혈중 암모니아 모니터링을 위한 실시간 모니터링 시스템 및 그 방법

... 본 발명은 혈중 암모니아 모니터링을 위한 실시간 모니터링 시스템 및 그 방법에 관한 것으로, 본 발명의 일 실시예에 따른 혈중 암모니아 모니터링을 위한 실시간 모니터링 시스템은 환자의 혈중 암모니아 농도를 측정하여 그 결과의 신호를 출력하는 혈중 암모니아 농도 측정장치; 블루투스 기능을 통해 상기 혈중 암모니아 농도 측정장치로부터 입력된 데이터를 표시, 저장, 관리하며, 그 결과의 신호를 출력하는 스마트폰; 상기 스마트폰으로부터 입력된 환자에 관한 여러가지 종류의 데이터를 데이터베이스화하는 빅 데이터 서버; 인터넷을 통해 상기 스마트폰으로부터 입력된 환자에 관한 여러가지 종류의 데이터 및 상기 빅 데이터 서버로부터 입력된 데이터에 근거하여 환자의 건강 상태 및 원격 진료 결과를 나타내는 신호를 상기 스마트폰으로 다시 전송하는 병원 서버를 포함한다. 또한, 본 발명에 따른 혈중 암모니아 모니터링을 위한 실시간 모니터링 방법은 혈중 암모니아 농도 측정장치에 의해 환자의 혈중 암모니아 농도를 측정하여 그 결과의 신호를 출력하는 단계; 블루투스 기능을 통해 상기 혈중 암모니아 농도 측정장치로부터 입력된 데이터를 스마트폰에 의해 표시, 저장, 관리하며, 그 결과의 신호를 출력하는 단계; 상기 스마트폰으로부터 입력된 환자에 관한 여러가지 종류의 데이터를 빅 데이터 서버에 의해 데이터베이스화하는 단계; 인터넷을 통해 상기 스마트폰으로부터 입력된 환자에 관한 여러가지 종류의 데이터 및 상기 빅 데이터 서버로부터 입력된 데이터에 근거하여 환자의 건강 상태 및 원격 진료 결과를 나타내는 신호를 병원 서버에 의해 상기 스마트폰으로 다시 전송하는 단계를 포함한다.

A DEVICE FOR MEASURING A PLURALITY OF PARAMETERS IN PATIENT SUBJECT TO A TREATMENT WITH RADIOPHARMACEUTICALS

APPARATUS AND METHOD OF MEASURING FATIGUE

An apparatus for measuring the fatigue of a user includes a first sensor configured to sense a factor causing the fatigue of a user; a second sensor configured to sense a brain wave signal of the user; and a processor configured to calculate a primary fatigue of the user based on the factor sensed by the first sensor, to calculate a secondary fatigue of the user based on the brain wave signal sensed by the second sensor, and to measure the fatigue of the user by using the primary fatigue and the secondary fatigue.

SYSTEMS, DEVICES, AND METHODS INCLUDING PARAMAGNETIC OSCILLATION, ROTATION, AND TRANSLATION OF HEMOZOIN ASYMMETRIC NANOPARTICLES IN RESPONSE TO DARK-FIELD OR RHEINBERG DETECTION OF THE PRESENCE OF HEMOZOIN

Systems, devices, and methods are described for providing a monitor/treatment device configured to, for example, detect hemozoin, as well as to monitor or treat a malarial infection.

DEVICES AND METHODS FOR DETERMINING A DISEASE STATE BASED TOTAL LENS FLUORESCENCE

A device is provided that may include an illuminator operable to interrogate at least a lens of an eye. The illuminator may include at least one light source and a lens positioned with respect to the light source to produce interrogating radiation. The device also may include a detector operable to image the total autofluorescence response of the lens of the eye as viewable through a pupil of the eye, the detector comprising an image sensor. The device can also include a controller operable to control operation of the illuminator and the detector. The controller may interrogate at least the lens of the eye by activating the illuminator for a select time, obtain at least one image of the total autofluorescence response of the lens at the detector during or immediately subsequent to the select time, and transmit the at least one image to a remote device.

РЕГУЛИРУЕМОЕ ВНУТРИРОТОВОЕ УСТРОЙСТВО ВЫДВИЖЕНИЯ НИЖНЕЙ ЧЕЛЮСТИ ВПЕРЕД ДЛЯ ПРЕДОТВРАЩЕНИЯ ХРАПА И АПНОЭ СНА

... 1. Внутриротовое регулируемое устройство выдвижения нижней челюсти вперед для предотвращения храпа и апноэ сна, состоящее из соединенных шин или пластин, повторяющих форму челюстей пациента, и предназначенное для протезирования в области одонтологии, задача которого заключается в выдвижении вперед нижней челюсти с целью предотвращения блокады циркуляции воздуха по дыхательным путям, отличающееся тем, что оно содержит винт (1), расположенный в полигональном цилиндрическом корпусе (2), в передней части которого имеется верхнее подвижное кольцо (3), разомкнутое или сомкнутое и сужающееся к центру, выступающее в качестве направляющей (4) для верхней штанги (5), прикрепленной к верхнечелюстной пластине (6), а в нижней части корпуса (2) выполнена продольная канавка (8), обеспечивающая перемещение внутреннего подвижного кольца (9) с резьбой (10), которое соединено с и перемещается винтом (1) и на котором расположено нижнее подвижное разомкнутое или сомкнутое кольцо (11), в котором имеется перпендикулярное ...

System und Verfahren zur Reduzierung eines Kinetose-Effekts bei mindestens einem Passagier eines Fahrzeugs

Die Erfindung betrifft ein System zur Reduzierung eines Kinetose-Effekts bei mindestens einem Passagier (1) eines Fahrzeugs (2), umfassend mindestens einen Kopfhörer (3) mit zwei Lautsprechern (6.1, 6.2) und mit mindestens einem ersten Ohrstecker (4.1), wobei der mindestens eine Kopfhörer (3) dazu eingerichtet ist, zumindest mittels einer in dem ersten Ohrstecker (4.1) integrierten Sensorvorrichtung (5) den Kinetose-Effekt im Gehörkanal des jeweiligen Passagiers (1) zu erfassen und mittels der beiden Lautsprecher (6.1. 6.2) in Abhängigkeit des erfassten Kinetose-Effekts akustische Signale zur Reduzierung des Kinetose-Effekts des jeweiligen Passagiers (1) bereitzustellen. Ferner betrifft die Erfindung auch ein Verfahren zum Betrieb eines solchen Systems.

Organism data processing method and device, storage medium and program

Provided is an organism data processing method and device, storage medium and program that is able to predict and control changes in the state of an organism. The level of expression of molecules in an organism is measured over a set time interval; the measured time-series data is divided into a periodic component, an environmental stimulus response component and a baseline component; a constant region of the time-series data is identified from variations in the baseline component or from the amplitude or periodic variations of the periodic component; and causal relationships within the identified constant region are identified. The relationship between the external environment and variations in the internal environment is identified and from the causal relationships within the identified constant region, changes in the state of the organism are inferred. Further, from the relationship between the external environment and variations in the internal environment, inferring disease onset in ...

HIGH-SENSITIVITY PRESSURE-SENSING PROBE

COMPUTER SYSTEM FOR DETERMINING A STATE OF MIND AND PROVIDING A SENSORY-TYPE ANTIDOTE TO A SUBJECT

Computer implemented method and system for achieving a preferred state of mind of a user are disclosed. In a first aspect, the method comprises detecting a biological marker (biomarker) of a user utilizing one or more sensors; and inferring a state of mind of the user based upon data received from the one or more sensors that are provided to computational hardware. Finally the method includes providing an antidote to the user if the inferred state of mind is different than the preferred state of mind utilizing an actuator. In a second aspect, the system comprises one or more sensors for detecting a biological marker (biomarker) of the user and computational hardware for inferring a state of mind of the user based upon data received from the one or more sensors. Finally the system includes an actuator for providing an antidote to the user if the inferred state of mind is different than a preferred state of mind.

FLUID FILLED IMPLANTS FOR TREATING OBSTRUCTIVE SLEEP APNEA

An implant (20) for treating obstructive sleep apnea includes a flexible chamber (22), a fluid reservoir (24) in fluid communication with the flexible chamber, and a fluid transfer assembly (26) in communication with the fluid reservoir and the flexible chamber for transferring fluid therebetween for selectively modifying the rigidity of the flexible chamber. The flexible chamber is implantable within the soft tissue of an oropharyngeal airway of a patient, such as within the tongue, the soft palate, or the pharyngeal wall. The fluid reservoir and the fluid transfer assembly are implantable within the inf ramandibular region of the patient. The fluid transfer assembly is selectively engageable by the patient for transferring fluid between the two chambers for modifying the rigidity, flexibility, and/or shape of the flexible chamber with minimal or no change to the volume of the implant.

BIOLOGICAL INFORMATION PROCESSING METHOD AND DEVICE, RECORDING MEDIUM AND PROGRAM

Provided is an organism data processing method and device, storage medium and program that is able to predict and control changes in the state of an organism. The level of expression of molecules in an organism is measured over a set time interval; the measured time-series data is divided into a periodic component, an environmental stimulus response component and a baseline component; a constant region of the time-series data is identified from variations in the baseline component or from the amplitude or periodic variations of the periodic component; and causal relationships within the identified constant region are identified. The relationship between the external environment and variations in the internal environment is identified and from the causal relationships within the identified constant region, changes in the state of the organism are inferred. Further, from the relationship between the external environment and variations in the internal environment, inferring disease onset in ...

Body Balance Measuring System

SYSTEM FOR MEASURING FAVORABLE IMPRESSIONDEGREE OF COUPLE

METHOD FOR SELECTING PATIENT WITH ARTHRITIS USING SELF-EXAMINATION

Disclosed is a method for selecting a patient with inflammatory arthritis and a patient with osteoarthritis using self-examination. The method comprises the steps of: providing a user with an inflammatory arthritis diagnostic questionnaire; determining a possibility of inflammatory arthritis of the user using an answer to the inflammatory arthritic diagnostic questionnaire; providing an osteoarthritis diagnostic questionnaire to the user and receiving an answer to the osteoarthritic diagnostic questionnaire according to a determination result of the possibility of inflammatory arthritis; and determining a possibility of osteoarthritis of the user by using the answer to the osteoarthritic diagnosis questionnaire. COPYRIGHT KIPO 2018 (S110) Providing a user with an inflammatory arthritis diagnostic questionnaire (S120) Determining a possibility of inflammatory arthritis of the user using an answer to the inflammatory arthritic diagnostic questionnaire (S130) Providing an osteoarthritis diagnostic ...

ODOUR SENSOR

A personnel recognition sensor comprises a multiplicity of differentially responding chemo-resistor elements, each element comprising a non-conductive substrate, a plurality of electrodes disposed on the substrate and one or more layers of a conductive polymer overlaying the electrodes, the conductive polymers of at least two of the elements being different; a detector responsive to signals provided by the multiplicity of elements and arranged to provide an output signal characteristic of the multiplicity of signals; the elements being disposed in a housing having an inlet arranged so that a gaseous sample passing into or through the inlet contacts all of the elements in use.

ЧУВСТВИТЕЛЬНЫЙ К ДАВЛЕНИЮ ЗОНД С ВЫСОКОЙ ЧУВСТВИТЕЛЬНОСТЬЮ

Изобретение относится к инвазивным медицинским устройствам. Медицинский зонд содержит вводимую трубку, имеющую продольную ось и дистальный конец, дистальный кончик, расположенный на дистальном конце вводимой трубки и сконфигурированный для введения в контакт с тканью тела, стык, который соединяет дистальный кончик с дистальным концом вводимой трубки, и датчик стыка, заключенный внутри зонда, для распознавания положения дистального кончика относительно дистального конца вводимой трубки, причем датчик стыка содержит первый и второй подузлы, которые расположены внутри зонда на противоположных соответствующих сторонах стыка, и каждый подузел содержит один или более магнитных измерительных преобразователей. Стык содержит упругий элемент, который сконфигурирован, чтобы деформироваться в ответ на давление, прикладываемое на дистальный кончик, когда он входит в соприкосновение с тканью, при этом упругий элемент содержит трубчатую деталь из эластичного материала, имеющую винтовой срез вдоль части ...

Methods for treating hyperbilirubinemia with stannsoporfin

I. Some embodiments relate to methods of treating hyperbilirubinemia comprising administrating a therapeutic amount of a metalloporphyrin to an infant. Administration may occur when the infant's measured total serum bilirubin levels are at or below about the level suggested by the AAP nomogram for initiating phototherapy, when the infant's measured total serum bilirubin levels are at about the level suggested for initiating phototherapy in an infant, or when the infant's measured total serum bilirubin levels are at about the level suggested for initiating phototherapy. Administration may occur without regard to the total serum bilirubin level of the infant. In some embodiments, administration of the metalloporphyrin does not cause QT prolongation. -1 17. WO 20131082559 PCTIUS2012/067484 *- T t4i i A-4 ---- 4 OW Eve 24 AD P A Op7o k* " Vo sna eAwam TOJ& 0 NaMA 'tst3eetaismi-'w-ar H-wa Red tFGR 1 ...

HIGH-SENSITIVITY PRESSURE-SENSING PROBE

A medical probe includes an insertion tube, having a longitudinal axis and having a distal end. A distal tip is disposed at the distal end of the insertion tube and is configured to be brought into contact with a body tissue. A joint couples the distal tip to the distal end of the insertion tube. A joint sensor, contained within the probe, senses a position of the distal tip relative to the distal end of the insertion tube. The joint sensor includes first and second subassemblies, which are disposed within the probe on opposite, respective sides of the joint and each include one or more magnetic transducers.

Pig growth prediction system based on ICT information based pig farm environment change

METHOD FOR MEASURING ACCURACY AND BALANCE OF LEFT AND RIGHT BIO-SIGNAL

The present invention relates to a method for measuring accuracy and balance of a left bio-signal and a right bio-signal. The objective of the method according to the present invention is to evaluate accuracy of a measured signal and left and right body balance, by measuring and comparing bio-signals like PPG and ECG of two channels measured at both hands such as a left finger, a right finger, a palm, and a wrist of an examinee at the same time. The objective of the present invention is achieved by including: a process of measuring each bio-signal through a sensor attached to a part of a left-side and right-side body of the examinee; a process of detecting R-R intervals (RRI) from each bio-signal measured through the sensor; and a process of calculating left and right balance and accuracy of the examinee in accordance with the detected RRI value. COPYRIGHT KIPO 2016 (AA) Start (BB) Starting to measure bio-signal (CC) Collecting signal (DD) Detecting each RRI (EE) Four RRI values are equal ...

MONITORING METHOD AND APPARATUS SIMULTANEOUSLY PERFORMING TAGET'S STATE SENSING AND INFORMATION OBTAINING

METHODS AND DEVICE ARRANGEMENT FOR PHYSICAL ACTIVITY THRESHOLDS REDUCING RISKS OF DIABETES, CARDIOVASCULAR DISEASES, INFLAMMATIONS, DEMENTIA, CANCERS AND MORTALITY IN SEDENTARY SUBJECTS

Systems, devices, and methods including a dark-field reflected-illumination apparatus

Systems, devices, and methods are described that modulate a specimen-background dark-field micrograph contrast.

Speech analysis algorithmic system and method for objective evaluation and/or disease detection

Systems and methods use patient speech samples as inputs, use subjective multi-point ratings by speech-language pathologists of multiple perceptual dimensions of patient speech samples as further inputs, and extract laboratory-implemented features from the patient speech samples. A predictive software model learns the relationship between speech acoustics and the subjective ratings of such speech obtained from speech-language pathologists, and is configured to apply this information to evaluate new speech samples. Outputs may include objective evaluation of the plurality of perceptual dimensions for new speech samples and/or evaluation of disease onset, disease progression, or disease treatment efficacy for a condition involving dysarthria as a symptom, utilizing the new speech samples.

Система содействия сердечно-легочной реанимации и способ мониторинга сердечно-легочной реанимации

Группа изобретений относится к медицинской технике. Система содействия сердечно-легочной реанимации (СЛР) содержит датчик, выполненный с возможностью измерения физиологического параметра для выработки сигнала датчика, передающего данные, касающиеся момента времени, в который завершен венозный возврат. Процессор выполнен с возможностью обработки сигнала датчика для определения моментов времени, в которые следует выполнять циклы компрессионных сжатий СЛР, на основании момента времени, в который завершен венозный возврат. Устройство вывода обеспечивает визуальные или звуковые выходные данные, относящиеся к моментам времени, в которые следует выполнять циклы компрессионных сжатий СЛР. Раскрыты устройство мониторинга для неотложной помощи и автоматизированное устройство сердечно-легочной реанимации. Технический результат состоит в обеспечении оптимальной частоты сжатий автоматизированным устройством СЛР с учетом физиологии конкретного пациента. 3 н. и 7 з.п. ф-лы, 8 ил.

Система содействия сердечно-легочной реанимации и способ мониторинга сердечно-легочной реанимации

Pharmaceutical dosage form for immediate release of an indolinone derivative

The present invention relates to a pharmaceutical dosage form delivering an immediate release profile containing the active substance 3-Z-[l-(4-(N-((4-methyl-piperazin-l-yl)- methylcarbonyl)-N-methyl-amino)-anilino)- 1 -phenyl-methylene] -6-methoxycarbonyl-2- indolinone-monoethanesulphonate.

Fluid filled implants for treating obstructive sleep apnea

An implant (20) for treating obstructive sleep apnea includes a flexible chamber (22), a fluid reservoir (24) in fluid communication with the flexible chamber, and a fluid transfer assembly (26) in communication with the fluid reservoir and the flexible chamber for transferring fluid therebetween for selectively modifying the rigidity of the flexible chamber. The flexible chamber is implantable within the soft tissue of an oropharyngeal airway of a patient, such as within the tongue, the soft palate, or the pharyngeal wall. The fluid reservoir and the fluid transfer assembly are implantable within the inf ramandibular region of the patient. The fluid transfer assembly is selectively engageable by the patient for transferring fluid between the two chambers for modifying the rigidity, flexibility, and/or shape of the flexible chamber with minimal or no change to the volume of the implant.

PLURALITY OF LAMINATION FOR SOFT TISSUE COMPRESSION SUPPORT, PROTECTION AND BRACING INTELLIGENT TEXTILE FOR EQUINE AND EQUESTRIAN SPORTS OR ACTIVITIES

Described here is a plurality of laminations and elements for constructing an improved Equestrian soft tissue compression support and intelligent textile for Equine, Equestrian Sports or Activities including but not limited to bracing. Scientific research and testing cites the inherent flaws to Prior Art which may make them undesirable to use. Prior Art has been shown to introduce allergies, heat damage, mechanical injuries and joint interference from material binding, bunching and migrating. Due to inherent flaws of Prior Art, they are not suitable for the plurality of laminations and elements to include fibertronics; organic electronics and other forms of e- textiles. Intelligent textiles can aid in expanding the working knowledge of equine or human sports related, repetitive use, occupational and mechanical injuries, rehabilitation treatment and prevention. The intelligent textile pertains generally to monitoring of joint and soft tissues that support a joint of a human or animal body ...

Pig growth prediction system based on ICT information based pig farm environment change

SLEEPINESS INDEX MONITERING APPARATUS USING BRAIN WAVE MEASUREMENT OF TEMPORAL LOBE

APPARATUS AND METHOD FOR EVALUATING DRIVER ACCEPTANCE

An apparatus and a method for evaluating driver acceptance are disclosed. The apparatus for evaluating driver acceptance comprises: a parameter collection unit for collecting a parameter according to driver acceptance; a sensitivity measurement unit for measuring sensitivity of the parameter by using the parameter collected by the parameter collection unit; an available acceptance range measurement unit for measuring an available acceptance range of the parameter by using the parameter collected by the parameter collection unit; and a driver acceptance evaluation unit for evaluating driver acceptance by using the available acceptance range measured by the available acceptance measurement unit and the sensitivity measured by the sensitivity measurement unit. By objectively evaluating the driver acceptance, the apparatus can simultaneously perform a product performance evaluation and a driver acceptance evaluation. COPYRIGHT KIPO 2018 (10) Parameter collection unit (20) Sensitivity measurement ...

DETECTION OF NUTRIENT DEFICIENCIES INFLUENCING OCULAR HEALTH

The present invention provides methods for identifying and treating subjects having nutrient deficiencies. A method for scoring nutritional deficiency in a subject's eye is also provided.

Device and method for liveness detection

A device for liveness detection is disclosed. The liveness detecting device has a simplest structure that principally comprises a light sensing unit and a signal processing module. Particularly, the signal processing module is configured for having a physiological feature extracting unit and a liveness detecting unit therein. The physiological feature extracting unit is adopted for extracting a first physiological feature from a PPG signal, or extracting a second physiological feature from the PPG signal that has been applied with a signal process. As such, through the first and second physiological features, the liveness detecting unit is able to determine whether a subject is a living body or not. The liveness detecting device does not use any camera unit and iPPG technology, such that the liveness detecting device has advantages of simple structure, low cost and immediately completing liveness detection.

Fluid filled implants for treating obstructive sleep apnea

An implant (20) for treating obstructive sleep apnea includes a flexible chamber (22), a fluid reservoir (24) in fluid communication with the flexible chamber, and a fluid transfer assembly (26) in communication with the fluid reservoir and the flexible chamber for transferring fluid therebetween for selectively modifying the rigidity of the flexible chamber. The flexible chamber is implantable within the soft tissue of an oropharyngeal airway of a patient, such as within the tongue, the soft palate, or the pharyngeal wall. The fluid reservoir and the fluid transfer assembly are implantable within the inf ramandibular region of the patient. The fluid transfer assembly is selectively engageable by the patient for transferring fluid between the two chambers for modifying the rigidity, flexibility, and/or shape of the flexible chamber with minimal or no change to the volume of the implant.

METHODS FOR TREATING HYPERBILIRUBINEMIA WITH STANNSOPORFIN

Some embodiments relate to methods of treating hyperbilirubinemia comprising administrating a therapeutic amount of a metalloporphyrin to an infant. Administration may occur when the infant's measured total serum bilirubin levels are at or below about t level suggested by the AAP nomogram for initiating phototherapy, when the infant's measured total serum bilirubin levels are at about the level suggested for initiating phototherapy in an infant, or when the infant's measured total serum bilirubin levels are at about the level suggested for initiating phototherapy. Administration may occur without regard to the total serum bilirubin level of the infant. In some embodiments, administration of the metalloporphyrin does not cause QT prolongation.

PLURALITY OF LAMINATION FOR SOFT TISSUE COMPRESSION SUPPORT, PROTECTION AND BRACING INTELLIGENT TEXTILE FOR EQUINE AND EQUESTRIAN SPORTS OR ACTIVITIES

Described here is a plurality of laminations and elements for constructing an improved Equestrian soft tissue compression support and intelligent textile for Equine, Equestrian Sports or Activities including but not limited to bracing. Scientific research and testing cites the inherent flaws to Prior Art which may make them undesirable to use. Prior Art has been shown to introduce allergies, heat damage, mechanical injuries and joint interference from material binding, bunching and migrating. Due to inherent flaws of Prior Art, they are not suitable for the plurality of laminations and elements to include fibertronics; organic electronics and other forms of e- textiles. Intelligent textiles can aid in expanding the working knowledge of equine or human sports related, repetitive use, occupational and mechanical injuries, rehabilitation treatment and prevention. The intelligent textile pertains generally to monitoring of joint and soft tissues that support a joint of a human or animal body ...

METHOD FOR FAST MAPPING ABILITY MEASUREMENT USING A QUICK INCIDENTAL LEARNING, RECORDING MEDIUM AND APPARATUS FOR PERFORMING THE METHOD

Wireless transmission medical device with a plurality of brainwave collection sensors of multichannel ECoG electrodes using F-TFTA for brain disease treatment

Method for generating breast masses according to the lesion characteristics and the system thereof

Systems, devices, and methods including paramagnetic oscillation, rotation and translation of hemozoin asymmetric nanoparticles in response to multi-harmonic optical detection of the presence of hemozoin

Systems, devices, and methods are described for providing a monitor/treatment device configured to, for example, detect hemozoin, as well as to monitor or treat a malarial infection.

DETERMINING A DOMINANT HAND OF A USER OF A COMPUTING DEVICE

In one example, a method includes determining, by a computing device, a plurality of features. Each feature from the plurality of features may be usable to determine a dominant hand of a user of the computing device. The method also includes receiving, by the computing device, a plurality of input values, each input value from the plurality of input values corresponding to the respective plurality of features, and determining, using a probabilistic model and based at least in part on at least one input value from the plurality of input values corresponding to the respective feature from the plurality of features, a hand of the user as a dominant hand of the user. The method also includes generating, based at least in part on the determined dominant hand of the user, a graphical user interface for display at a presence-sensitive display operatively coupled to the computing device.

METHOD AND SYSTEM FOR PREDICTING CHILDHOOD OBESITY

A method of predicting likelihood for childhood obesity, comprises: obtaining a plurality of parameters, wherein at least a few of the parameters characterize an infant or toddler subject. A machine learning procedure trained for predicting likelihoods for childhood obesity is feed with the plurality of parameters. An output indicative of a likelihood that the infant or toddler subject is expected to develop childhood obesity is received from the procedure. The output is related non-linearly to the parameters.

Device and method to determine objectively visual memory of images

Apparatus, system, and computer readable media determine the probability of visual recognition of an image by a subject using electroencephalography (EEG) corresponding to a Visual Evoked Potential (VEP). The apparatus comprises means for presenting a series of visual stimuli corresponding to said image to evoke EEG signals. The visual stimuli of the image are presented in an orientation sequence based on a timing cycle. At least one prism is provided for placement in front of the series of visual stimuli corresponding to said image. The EEG signals evoked in response to said visual stimuli and said prism placed in front of said visual stimuli are recorded and processed by a processor. VEP is generated corresponding to the presence of a shift and thereby provides object statistic reliability of the visual recognition of the image by the subject.

METHOD FOR SENSING OF BIOMETRIC DATA AND USE THEREOF FOR BIDIRECTIONAL COMMUNICATION WITH NETWORKED DEVICES

A method of using a sensor platform of a garment of a wearer in order to interact with a remote networked device using a plurality of sensed biometric data, the method comprising: receiving from the sensors a set of the plurality of biometric data; comparing the set to a data model including a plurality of model data parameters; determining whether said comparing indicates a need for a command to be sent to the remote networked device in order to effect a change in an operational characteristic of the networked device; sending the command to the networked device; receiving a further set of the plurality of biometric data; further comparing the further set to the data model; and determining whether said further comparing indicates a need for a further command to be sent to the remote networked device in order to further effect a change in an operational characteristic of the networked device.

METHOD, SYSTEM, AND COMPUTER READABLE MEDIUM FOR GENERATING PULSE OXIMETRY PREDICTIVE SCORES (POPS) FOR PREDICTING ADVERSE OUTCOMES IN PRETERM INFANTS

A method and system for generating pulse oximetry predictive scores for predicting adverse outcomes in preterm infants.

CPR ASSISTANCE SYSTEM AND CPR MONITORING METHOD

A CPR assistance system comprises a sensor for making a physiological measurement to generate a sensor signal which conveys information concerning the point in time at which venous return is completed. Time points are then determined at which CPR compression cycles should be administered, and output information is provided relating to the determined time points. The output information may be visual or audible advice to a person giving CPR or it may be control information for controlling an automated CPR system.

PROCESSOR FOR PROCESSING SKIN CONDUCTANCE DATA AND DEVICE FOR DETECTING AT LEAST ONE STAGE OF BURNOUT AND/OR CHRONIC FATIGUE SYNDROME OF A LIVING BEING

The present invention relates to a processor for processing skin conductance data of a living being, comprising an input unit (12) for receiving a skin conductance data signal (13) comprising a plurality of data peaks, a calculating unit (14) for computing a skin conductance peak data signal over a long-term period by deriving a feature related to said data peaks from said skin conductance data signal (13) and forming a summation of said feature per time unit and an analyzing unit (16) for analyzing an average and/or an absolute value of said skin conductance peak data signal over at least a portion of said period to get information on at least one stage of burnout and/or chronic fatigue syndrome of said living being.

PHARMACEUTICAL DOSAGE FORM FOR IMMEDIATE RELEASE OF AN INDOLINONE DERIVATIVE

The present invention relates to a pharmaceutical dosage form delivering an immediate release profile containing the active substance 3-Z-[l-(4-(N-((4-methyl-piperazin-l-yl)- methylcarbonyl)-N-methyl-amino)-anilino)- 1 -phenyl-methylene] -6-methoxycarbonyl-2- indolinone-monoethanesulphonate.

Functional cloths

Computer system for determining a state of mind and providing a sensory-type antidote to a subject

Computer implemented method and system for achieving a preferred state of mind of a user are disclosed. In a first aspect, the method comprises detecting a biological marker (biomarker) of a user utilizing one or more sensors; and inferring a state of mind of the user based upon data received from the one or more sensors that are provided to computational hardware. Finally the method includes providing an antidote to the user if the inferred state of mind is different than the preferred state of mind utilizing an actuator. In a second aspect, the system comprises one or more sensors for detecting a biological marker (biomarker) of the user and computational hardware for inferring a state of mind of the user based upon data received from the one or more sensors. Finally the system includes an actuator for providing an antidote to the user if the inferred state of mind is different than a preferred state of mind.

BIO-INFORMATION-MESSEINRICHTUNG

In der Biologische-Information-Messeinrichtung der vorliegenden Erfindung beinhaltet eine Spange (30) ein erstes Plattenteil (35), welches eine Plattenform besitzt, und wobei es an dem anderen Endteil (h) eines zweiten Plattenrahmengliedes (30b) fixiert ist, und ein zweites Plattenteil (36), welches eine Plattenform besitzt und drehbar ist. Das zweite Plattenteil (36) besitzt ein herausragendes Teil (36h), welches sich unterhalb des ersten Plattenteils (35) erstreckt, wenn das zweite Plattenteil (36) eine äußere Oberfläche des ersten Plattenteils (35) überlappt. Ein erstes Fixierelement (32) ist auf einer Seite des herausragenden Teils (36h) bereitgestellt, welches eine innere Oberfläche wird, wenn das zweite Plattenteil (36) die äußere Oberfläche des ersten Plattenteils (35) überlappt. Ein zweites Fixierelement (25), welches mit dem ersten Fixierelement (32) einrastbar ist, ist auf der äußeren Oberfläche des Frontendteils des Armbandes bereitgestellt. Ein erster Einrastvorsprung (35c) ...

Methods for treating hyperbilirubinemia with stannsoporfin

I. Some embodiments relate to methods of treating hyperbilirubinemia comprising administrating a therapeutic amount of a metalloporphyrin to an infant. Administration may occur when the infant's measured total serum bilirubin levels are at or below about the level suggested by the AAP nomogram for initiating phototherapy, when the infant's measured total serum bilirubin levels are at about the level suggested for initiating phototherapy in an infant, or when the infant's measured total serum bilirubin levels are at about the level suggested for initiating phototherapy. Administration may occur without regard to the total serum bilirubin level of the infant. In some embodiments, administration of the metalloporphyrin does not cause QT prolongation. -114- WO 20h13/082559PCY SO /O~~ -- --->$ ckk '. ~4 4:. . >~ *P44>&f'4>r ' 4 z~W4'4. 44 k~ 4 t -m-N1$ 9k ~%~ ...

METHOD, SYSTEM, AND COMPUTER READABLE MEDIUM FOR GENERATING PULSE OXIMETRY PREDICTIVE SCORES (POPS) FOR PREDICTING ADVERSE NEUROLOGICAL DEVELOPMENT IN PRETERM INFANTS

A method for generating pulse oximetry predictive scores for adverse preterm infants.

Virtual health assistant for promotion of well-being and independent living

An electronic device for providing health information or assistance includes an input configured to receive at least one type of signal selected from sound signals, verbal signals, non-verbal signals, and combinations thereof, a communication module configured to send information related to the at least one user and his/her environment to a remote device, including the sound signals, non-verbal signals, and verbal signals, the remote device being configured to analyze a condition of the at least one user and communicate condition signals to the electronic device, a processing module configured to receive the condition signals and to cause the electronic device to engage in a passive monitoring mode or an active engagement and monitoring mode, the active engagement and monitoring mode including, but not limited to, verbal communication with the at least one user, and an output configured to engage the at least one user in verbal communication.

Biological information processing method and device, recording medium and program

Provided is a biological information processing method and a device, a recording medium and a program that are able to predict and control changes in the state of an organism. The expression level of molecules in an organism is measured over a specific time interval; the measured time-series data is divided into a periodic component, an environmental stimulus response component and a baseline component; constant regions of the time-series data are identified from variations in the baseline component or from the amplitude or periodic variations of the periodic component; and causal relation between the identified constant regions is identified. The relation between the external environment and variations in the internal environment is identified and from the identified causal relation between the constant regions, changes in the state of the organism are inferred.

Methods for treating hyperbilirubinemia with stannsoporfin

I. Some embodiments relate to methods of treating hyperbilirubinemia comprising administrating a therapeutic amount of a metalloporphyrin to an infant. Administration may occur when the infant's measured total serum bilirubin levels are at or below about the level suggested by the AAP nomogram for initiating phototherapy, when the infant's measured total serum bilirubin levels are at about the level suggested for initiating phototherapy in an infant, or when the infant's measured total serum bilirubin levels are at about the level suggested for initiating phototherapy. Administration may occur without regard to the total serum bilirubin level of the infant. In some embodiments, administration of the metalloporphyrin does not cause QT prolongation. -114- WO 20h13/082559PCY SO /O~~ -- --->$ ckk '. ~4 4:. . >~ *P44>&f'4>r ' 4 z~W4'4. 44 k~ 4 t -m-N1$ 9k ~%~ ...

FLUID FILLED IMPLANTS FOR TREATING OBSTRUCTIVE SLEEP APNEA

An implant (20) for treating obstructive sleep apnea includes a flexible chamber (22), a fluid reservoir (24) in fluid communication with the flexible chamber, and a fluid transfer assembly (26) in communication with the fluid reservoir and the flexible chamber for transferring fluid therebetween for selectively modifying the rigidity of the flexible chamber. The flexible chamber is implantable within the soft tissue of an oropharyngeal airway of a patient, such as within the tongue, the soft palate, or the pharyngeal wall. The fluid reservoir and the fluid transfer assembly are implantable within the inf ramandibular region of the patient. The fluid transfer assembly is selectively engageable by the patient for transferring fluid between the two chambers for modifying the rigidity, flexibility, and/or shape of the flexible chamber with minimal or no change to the volume of the implant.

DEVICE FOR ELECTROMAGNETIC STRUCTURAL CHARACTERIZATION

HEIGHT ADJUSTABLE SMART PILLOW

생체 상태 조절 장치 및 이를 이용한 조절 방법

... 제안기술은 생체 상태 조절 장치 및 이를 이용한 조절 방법에 관한 것으로, 더욱 상세하게는 병사의 생존성 극대화를 위해 필요한 여러 가지 장치들을 하나의 통합시스템으로 구성하여 착용함으로써 병사의 생체 신호를 기반으로 생체 상태를 확인하고 처리할 수 있는 조절 장치 및 이를 이용한 조절 방법에 관한 발명이다.

Peripheral neural interface via nerve regeneration to distal tissues

At least partial function of a human limb is restored by surgically removing at least a portion of an injured or diseased human limb from a surgical site of an individual and transplanting a selected muscle into the remaining biological body of the individual, followed by contacting the transplanted selected muscle, or an associated nerve, with an electrode, to thereby control a device, such as a prosthetic limb, linked to the electrode. Simulating proprioceptive sensory feedback from a device includes mechanically linking at least one pair of agonist and antagonist muscles, wherein a nerve innervates each muscle, and supporting each pair with a support, whereby contraction of the agonist muscle of each pair will cause extension of the paired antagonist muscle. An electrode is implanted in a muscle of each pair and electrically connected to a motor controller of the device, thereby simulating proprioceptive sensory feedback from the device.

Systems and methods for monitoring and detecting symptoms of infectious conditions

Systems and methods may include a first monitoring device positioned at a first location to monitor a monitored environment; and a second monitoring device positioned at a second location to monitor the monitored environment, wherein the first and second monitoring devices calibrate each other based on respective fiducial markers; wherein the first and second monitoring devices each comprise a processor and a memory coupled to the processor, the memory storing a plurality of instructions, which when executed by the processor, cause the processor to perform the operations of: detecting presence of the individual in the monitored environment; determining whether the condition of interest of the individual exceeds a determined threshold; based on the condition of interest of the individual exceeding the determined threshold, transmitting the condition of interest to a remote server to determine at least one of a social distancing breach and an identification of another person whom the individual ...

Biological information measurement device, biological information measurement method, and body composition measurement device

To accurately acquire body composition information using data acquired by another device. Thus, there is provided a body composition monitor with scale including a communication unit for allowing input of biological component information (cross-sectional area, site length, subcutaneous fat percentage, visceral fat percentage, etc.) of a living body measured with another device such as an MRI, where step of calculating the body composition of the living body based on the biological component information, an impedance detected by an impedance detection unit, and a weight measured by a load detection unit is executed.

Устройство визуализации поверхностных вен

Настоящая полезная модель относится к медицинской технике и медицинскому оборудованию, а именно к неинвазивному портативному устройству для визуализации подкожных вен с использованием источников света в видимом световом диапазоне. Предлагаемое устройство может быть использовано для неинвазивной визуализации периферийных подкожных вен при проведении таких венозных манипуляций, как: введение внутривенных инъекций, забор крови из вены, установка внутривенных катетеров, проведение склеротерапии.Сущность полезной модели заключается в том, что визуализатор вен состоящий из корпуса в форме рукояти для хвата, двух элементов крепления печатной платы управления, проводного соединения, аккумуляторной батареи, коммутационного элемента, оптической линзы и крышки, имеет в своем составе печатную плату со светодиодами и токоограничивающими резисторами, изготовленную из алюминия. Использование алюминия позволяет предотвратить повышение температуры рабочей поверхности устройства свыше 46°С за счет отведения тепла от светодиодов, а также позволяет предотвратить перегрев светодиодов. Корпус имеет рабочую область подсветки в форме разомкнутого овала с прорезью 10-16 мм для проведения внутривенных инъекций, установки катетеров или забора крови. Светодиоды находятся в параллельном включении, каждый светодиод последовательно соединен с токоограничивающим резистором, что позволяет сформировать пороговое напряжение для каждого светодиода, которое не будет зависеть от пороговых напряжений других светодиодов в цепи, а также позволяет ограничить рабочий ток каждого светодиода. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 205 830 U1 (51) МПК A61B 5/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ (52) СПК A61B 5/0059 (2021.05); A61B 5/0077 (2021.05); A61B 5/489 (2021.05) (21)(22) Заявка: 2021110499, 15.04.2021 (24) Дата начала отсчета срока действия патента: (73) Патентообладатель(и): Общество с ограниченной ответственностью "МЭЙДЖИК ВЬЮ" (RU) ...

Устройство для визуализации вен в инфракрасном диапазоне

Настоящая полезная модель относится к медицинской технике и медицинскому оборудованию, а именно к неинвазивному портативному устройству для визуализации подкожных вен с использованием источников света в инфракрасном (ИК) диапазоне и ИК-камеры. Предлагаемое устройство может быть использовано для неинвазивной визуализации периферийных подкожных вен при проведении таких венозных манипуляций, как: введение внутривенных инъекций, забор крови из вены, установка внутривенных катетеров, проведение склеротерапии, проведение диагностики и исследования сосудов и сосудистых нарушений. За счет использования длин волн ближнего ИК-диапазона происходит контрастная визуализация вен, так как свет с длиной волны более 700 нм проникает глубже в кожу. При этом ближний ИК-свет минимально поглощается меланином (высокомолекулярный пигмент кожи), но сильно поглощается кровью в венах. Это позволяет дифференцировать кровеносные сосуды и окружающие ткани. В частности, ближний ИК-свет, попадающий на участок тела человека, поглощается кровеносными сосудами. Чем больше ближний ИК-свет поглощается, тем меньше происходит его отражение, которое фиксирует ИК-камера. Чем меньше поглощают ближний ИК-свет окружающие ткани, тем больше они его отражают. Поэтому, изображение вен, полученное ИК-камерой, имеет темную контрастную структуру, а окружающие ткани имеют более светлый оттенок. Сущность полезной модели заключается в том, что устройство для визуализации вен в инфракрасном диапазоне, состоящее из принимающего устройства, корпуса, инфракрасной камеры с инфракрасными светодиодами и датчиком освещенности, соединенных между собой первой печатной платой, микроконтроллера, контроллера аккумуляторной батареи и драйвера инфракрасных светодиодов, соединенных между собой второй печатной платой, кнопки включения и аккумуляторной батареей, соединенных со второй печатной платой проводным соединением, передает изображение вен по беспроводному соединению Wi-Fi принимающему устройству (планшету, монитору, ...

Systems, devices, and methods for monitoring an under foot load profile of a patient during a period of partial weight bearing

Systems, devices, and methods for measuring an under foot load profile of a patient during a period of partial weight bearing are described. The system may include a walking boot cast. A housing, including an inner surface and an upper surface that cooperate to define an inner cavity, may be oriented with respect to a patient's leg. The upper surface may be slidably received within the inner cavity in a piston and cylinder configuration or may be otherwise configured. The system may include a pressure sensor configured to monitor the load profile of a patient during the desired period of partial weight bearing. The pressure sensor may be located below the upper surface. The system may include a noncompressible force transmitter positioned within the inner cavity and at least partially encapsulating an upper portion of the pressure sensor to transmit pressure within the housing to the pressure sensor.

Apnea type determining apparatus and method

An apnea classification system provides for apnea monitoring and differentiation based on several sleep apnea related parameters for diagnostic and therapeutic purposes. Monitoring of such sleep apnea related parameters allows the apnea classification system to differentiate among the different types of apnea and hypopnea and to identify an occurrence of periodic respiration. This information may then be used to determine the best method of therapy, or adjust current therapy parameters to more effectively treat a subject.

Automated detection of sleep and waking states

Determining low power frequency range information from spectral data. Raw signal data can be adjusted to increase dynamic range for power within low power frequency ranges as compared to higher-power frequency ranges to determine adjusted source data valuable for acquiring low power frequency range information. Low power frequency range information can be used in the analysis of a variety of raw signal data. For example, low power frequency range information within electroencephalography data for a subject from a period of sleep can be used to determine sleep states. Similarly, automated full-frequency spectral electroencephalography signal analysis can be useful for customized analysis including assessing sleep quality, detecting pathological conditions, and determining the effect of medication on sleep states.

Seizure detection using coordinate data

A seizure detection device includes a coordinate data interface configured to receive coordinate data for a human, a memory to store coordinate data for a defined location of the human, and a seizure detector configured to identify a seizure event responsive to the coordinate data.

Medical device and methods of monitoring a patient with renal dysfunction

Embodiments relate to a method of monitoring physiological parameters of a patient with renal dysfunction. The method includes electrically connecting one or more medical device electrodes with a measurement site of a patient, generating one or more first stimulation signals sufficient to provide input physiological parameters specific to the patient, measuring one or more first bioimpedance values from the generated signals, analyzing at least one of the input physiological parameters within the one or more first bioimpedance values and generating a personalized dialysis program. The systems and methods can further provide essentially real-time data of patient undergoing treatment and control of treatment to a patient.

Devices and methods for respiratory variation monitoring by measurement of respiratory volumes, motion and variability

This invention is directed to devices and methods for assessing a patient. The devices have at least one impedance measuring element functionally connected to a programmable element, programmed to analyze an impedance measurement, and to provide an assessment of at least one respiratory parameter of the patient. Preferably the device includes electronics which aid in calibration, signal acquisition, conditioning, and filtering.

Apparatus, System and Method for Ultrasound Powered Neurotelemetry

The present embodiments provide an apparatus, system, and method for ultrasound powered neurotelemetry. In one embodiment, the apparatus includes a piezoelectric element configured to receive an ultrasonic pulse and convert the electronic pulse into an electric potential. A diode may be coupled to the piezoelectric element, the diode configured to cause an electric current to flow in response to the electric potential. The apparatus may additionally include a reference electrode and a stimulating electrode coupled to the diode. The reference electrode may sense bioelectric activity in a region of body tissue located in proximity to the reference diode. The stimulating electrode may emit a carrier signal, wherein the carrier signal is modulated in response to the bioelectric activity sensed by the reference electrode.

Multiple section parenteral drug delivery apparatus

The invention relates to a parenteral therapeutic agent delivery device. The therapeutic agent delivery device has a disposable section and an implant section suitable for long term implantation within the tissue of a subject. When necessary, the disposable section can be detached from the implant section, and a new disposable section can be attached. The disposable section may contain a reservoir containing the therapeutic agent, a pump for dispensing the therapeutic agent, controlling circuitry for regulating the dispensing of the therapeutic agent, and transceiver circuitry and an antenna for wireless communication with external devices.

Medical device for glucose monitoring or regulation

A medical device comprising a pressure generating means adapted to displace a liquid, a sensor adapted to measure a flow resistance, and an implantable member comprising an analyte responsive porous membrane which reversibly changes its porosity subject to changes in analyte concentration occurring in the solution surrounding the implantable member. The analyte may in particular be glucose. The medical device may also be used for drug administration.

Device and method for biasing lung volume

A device and method is provided for biasing lung volume by electrically stimulating tissue associated with the diaphragm or phrenic nerve at a low level.

Method and System For Patient-Specific Modeling of Blood Flow

Embodiments include a system for planning treatment for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of an anatomical structure of the patient, create a three-dimensional model representing at least a portion of the anatomical structure of the patient based on the patient-specific data, and determine a first fractional flow reserve within the anatomical structure of the patient based on the three-dimensional model and information regarding a physiological condition of the patient. The at least one computer system may be further configured to receive input from a user regarding a plan of treatment, modify the physiological condition of the patient based on the received input, and determine a second fractional flow reserve within the anatomical structure of the patient based on the modified physiological condition of the patient.

Method and device for monitoring and improving arteriogenesis

A method for determining an arteriovascular condition of a subject having an arterial blood flow is shown. The method involves determining a temporal progression of an instantaneous blood flow condition of the arterial blood flow as well as deriving a slew rate of the temporal progression during an increase of the temporal progression. In addition, an arteriovascular condition indicator device is shown, which comprises: an input for receiving an input signal representing an instantaneous arterial blood flow condition of a subject and a slew rate monitor connected to the input. A corresponding control device for providing an activation signal is also shown. The control device comprises a maximum detector connected to the slew rate monitor. A method for stimulation of arteriogenesis is also shown, wherein a temporal progression of an instantaneous blood flow condition is monitored, a slew rate of the temporal progression is derived, and the maximum of the slew rate is determined. An external pressure is applied repeatedly to the arteriovascular section in synchronization with the occurrence of the determined maximum.

Communication System Incorporated in an Ingestible Product

The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can also be associated with food and communicate data about ingestion of food material to a receiver.

Optical measurement apparatus

An optical measurement apparatus has a light source section, a light receiving section, and a light guiding section. The light source section has a light emitting surface that emits light. The light receiving section has a light receiving surface that receives the light emitted by the emitting surface of the light source to be incident into a body through a surface of the body and which is emitted out of the body after propagating inside the body, the receiving surface facing a direction orthogonal to the emitting surface of the light source, and the receiving section outputting a signal indicative of an amount of the light received by the receiving surface. The light guiding section is provided on a path of the light emitted from the emitting surface and received by the receiving surface to change a traveling direction of the light.

System and method for physiological monitoring

Apparatus, systems, and methods for monitoring a sensor module mounted in a sensor platform, wherein the sensor platform includes an adhesive side and a pocket, wherein the pocket is designed to receive the sensor module, to facilitate sensing by the sensor module of physiological attributes, and to allow insertion and removal of the sensor device from the pocket.

Metrics and algorithms for interpretation of muscular use

A muscle assessment method utilizing a computing system, surface electromyometry (sEMG) sensors, and other sensors to gather data for one or more subjects engaged in an activity through operably coupling the one or more sensors to the computing system, and directing a computing system to select one or more muscle assessment protocols related to a number of different metrics. For a user subject engaged in a physical activity, assessing muscle condition, the muscle activity, and statistically related averages provide information to the user and about muscle and whole body fitness.

Blood Flow Monitoring

The present invention relates to a method of utilizing photoplethysmography obtained from a central site and a non-central site to detect a low blood flow or low blood volume condition. Also disclosed are apparatuses and systems designed to acquire and process physiological information based on photoplethysmograpy signal information from dual sites.

Method and Apparatus of Neural Signal Determination and Therapy Enhancement

A method and device are provided that detect and identify a neural signal by type and optionally or automatically provide a signal that affects a nerve carrying the neural signal. A plurality of electrodes is positioned along a nerve and monitors the electrical activity of the nerve. The invented system analyzes the monitored data to determine when the monitored activity can be identified as a known type of bioelectric signal, e.g., a pain nerve signal. The system may optionally attempt to affect, disrupt, diminish, nullify or block transmission of bioelectric signals along the nerve, e.g., by directing electrical energy through an electrode to nullify a bioelectric signal along a pain nerve.

Method and apparatus for corrective secondary saccades analysis with video oculography system

A video oculography system for calculation and display of Corrective Secondary Saccades Analysis is disclosed. A method for Objective Diagnostics of at least one of traumatic brain injury, Internuclear Opthalmopligia, Ocular Lateral Pulsion, Progressive Supernuclear Palsy And Glissades comprises the steps of using a VOG system to calculate corrective saccades. The video oculography based system for the subject is configured to collect eye images of the patient in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion. The video oculography based system collects eye movement data wherein at least one fixation target is presented to the subject in a defined position configured to yield a voluntary saccadic eye response from at least one eye of the patient. The latency, amplitude, accuracy and velocity of each respective corrective saccade and totals latency and accuracy is calculated.

Diagnostic device and method for sensing hydration state of a mammalian subject

Timed sensing of collection of saliva in a liquid collection element of predetermined volumetric capacity may be used to determine salivary secretion rate, as may be indicative of state of euhydration or dehydration. Sensing of salivary flow rate may be further augmented by sensing concentration of at least one analyte in saliva (e.g., with an immunochromatographic assay performed in a lateral flow device) in order to determine a state of euhydration or dehydration. Production of saliva may be stimulated, and collected saliva may be analyzed to generate an analyte detection signal that indicative of presence and/or correlative of concentration of at least one analyte in the collected saliva to sense a state of euhydration or dehydration.

Biological signal display apparatus

A biological signal display apparatus includes: a stimulation unit which performs stimulation on a living body; a measurement unit which measures an evoked response evoked by the stimulation; a calculator which calculates a feature amount of the evoked response; a display unit; and a display controller which, based on the feature amount calculated by the calculator, displays a bar-shaped image on the display unit, each time when the stimulation is performed, the bar-shaped image corresponding with the evoked response on the display unit.

Management Method And System For Implementation, Execution, Data Collection, and Data Analysis Of A Structured Collection Procedure Which Runs On A Collection Device

A collection device for performing a structured collection procedure may include a processor that executes program instructions communicably coupled to at least one memory. The processor can initiate a schedule of events of the structured collection procedure upon one or more entry criterions being met and segregate the at least one memory into a primary data store and a secondary data store. The processor can write structured patient data collected in accordance to the schedule of events to the secondary data store. The processor can transform a relevant portion of the structured patient data into an evaluated data object. The processor can generate a data abstraction based in part upon the evaluated data object. The processor can link the primary data store and the secondary data store with the data abstraction.

Agents and methods for denervation

Various agents are described to denerve, modulate, or otherwise affect the renal nerves and other neural tissue. Also, various delivery devices are described to deliver an agent locally to the renal nerves. The delivery devices are positioned in the renal artery and penetrate into the wall of the renal artery to deliver the agent to the renal nerves. The delivery devices may be used to deliver the agent according to longitudinal position, radial position, and depth of the renal nerves relative to the renal artery. In addition, various methods are described to denervate, modulate, or otherwise affect the renal nerves and other neural tissue.

In Vivo 1H Magnetic Resonance Spectroscopy For The Diagnosis Of Testicular Function And Disease

This invention relates to the use of 1 H magnetic resonance spectroscopy for the diagnosis of testicular function and disease.

Enhancement of Biological Functioning by the use of Electromagnetic and Magnetic Fields

Systems and methods are provided for treating a living being with multiple, concurrent, superimposed non-phase-locked signals, at physiologically acceptable intensities and duty cycles such that the signals entrain the tissue. Preferred signals are electromagnetic, and at least one of the frequencies is selected from the list consisting of 7.6 Hz +/−2 Hz. 70.25 Hz+/−0.25 Hz, 71.25 Hz+/−0.25 Hz, and 3040 Hz +/−10 Hz. Among other things, it is contemplated that the signals can be used to create a subjective reduction in pain, mood improvement, to treat osteoporosis, to enhance cardiac function, and/or affect the hypothalamic pituitary axis.

Automated adaptive muscle stimulation method and apparatus

An automated adaptive muscle stimulation system and method are disclosed. The stimulation system includes at least one electrode assembly adapted to deliver a muscle stimulation signal to the tissue of a user, a sensor system adapted to detect a muscle response, and an electrical stimulation device operably coupled to the at least on electrode assembly and the sensor system, the electrical stimulation device including a control system operable to automatically diagnose at least one characteristic of a muscle from the detected muscle response and adjust at least one parameter of the muscle stimulation signal in response thereto to deliver an adjusted muscle stimulation signal. A dual mode muscle stimulation system adapted to accept first and second data sets and provide first and second levels of treatment data is also disclosed.

Methods and means for clinical investigations

Described are methods for testing at least one effect of a pharmaceutical substance in a subject, which include administering a pharmaceutical substance to the subject, measuring with at least one sensor contained within a mobile sensor system, at the subject or in close proximity to the subject, at least one parameter value indicative of a the subject's body function, transmitting at least one sensor system signal associated with the at least one parameter value to a receiver contained within a mobile base unit, the receiver being provided with a means for wireless transmission, and wirelessly transmitting a mobile base unit signal associated with the at least one sensor system signal from the receiver to a back-end system, wherein at least the back-end system correlates the at least one parameter value with and/or displays a representation of the at least one effect of the pharmaceutical substance.

Real-Time Evaluation of CPR Performance

A computer-implemented method for providing summary information for lifesaving activities is disclosed. The method involves sensing one or more activities that are repeatedly and cyclically performed on a victim by a rescuer; identifying a cyclical timing interval over which performance is to be analyzed for a integer number of cycles of the one or more activities, and gathering data from the sensing of the one or more activities during the time interval; generating, from analysis of the one or more activities, summary data that condenses data sensed for the one or more activities into a summary of the one or more activities; and providing, for display to a user, a visual summary of the performance of the one or more activities over the identified time interval.

Devices for creating passages and sensing blood vessels

Devices and methods are disclosed for creating passages in tissue and detecting blood vessels in and around the passages. The devices may be used to create channels for altering gaseous flow within a lung to improve the expiration cycle of an individual, particularly individuals having Chronic Obstructive Pulmonary Disease (COPD). In addition, the devices may be used to sample tissue during biopsy or other medical procedures where perforating a blood vessel could result in injury to a patient.

Devices for diagnosing sleep apnea or other conditions and related systems and methods

A system includes a sensor device having a body configured to be inserted into an airway of a patient and one or more sensors mounted in or on the body. The one or more sensors are configured to collect sensor data associated with the airway of the patient. The system also includes a signal analyzer configured to analyze the sensor data. The one or more sensors could include one or more microphones. The signal analyzer could identify volume and/or pitch characteristics of the sensor data, perform pattern recognition to identify one or more patterns using the volume and/or pitch characteristics, and use the one or more patterns to identify a type, a location, and/or a degree of airway obstruction. This could be done, for instance, to determine if the patient suffers from obstructive sleep apnea or other condition that affects his or her airway.

Determination and application of glucose sensor reliability indicator and/or metric

Disclosed are a system and method for determining a metric and/or indicator of a reliability of a blood glucose sensor in providing glucose measurements. In one aspect, the metric and/or indicator may be computed based, at least in part, on an observed trend associated with signals generated by the blood glucose sensor.

Orifice probe apparatus and a method of use thereof

An orifice probe, particularly for detecting if a patient has or has a risk of having cauda equina syndrome and a method for using same, the probe having a body for insertion into the anus of a patient, a sensing device for measuring at least one of the rectal tone and perianal or rectal sensation, and an output device for yielding at least one of the measurement of the rectal tone of the patient and whether the patient has perianal or rectal sensation.

Detection and treatment of autoimmune disorders

Disclosed herein are methods of treatment of autoimmune diseases such as systemic lupus erythematosus (SLE) as well as clinical assays for detection of autoimmune disease activity in patients utilizing a PD1 ligand.

System and Method for Pain Reduction

Systems and methods for treating pain are described. Systems and methods for treating pain using video games, tilt tables and bio-sensors are described wherein the level of the video game is controlled by a computer based on the feedback from a patient. Corresponding systems are also disclosed.

Focal medication titration system

A system is provided for implantation into the skull of a patient including a device to detect the onset and/or existence of a neurological condition and deliver a medication to prevent the neurological condition, and/or to improve or sustain normal neurological function. Methods for utilizing the system and device are also provided.

Device, system and method for meal detection for interfacing with and controlling auxiliary devices associated therewith

The present invention relates to a device, system and method for detecting meal event in a subject and in particular to such a device, system and method for communicating and controlling auxiliary devices and/or systems associated therewith.

System and method for facial nerve monitoring during facial surgery

An apparatus for monitoring the activity of a surgeon. At least one wireless sensing unit is provided for monitoring potential damage to a nerve and is located at a first location of a body being operated on by a surgeon. The wireless sensing unit senses a change in the body at the first location resulting from potential damage to the nerve occurring at a second location of the body remote from the first location. The wireless sensing unit produces a wireless sensed change output signal indicative of the change in the body which is received by a receiver and generates a corresponding received output signal. An analyzer unit receives and analyzes the received output signal to determine the change in the body. An indicator responsive to the output of said analyzer unit indicates the change in the body to indicate the potential damage to the nerve the surgeon.

Handheld excitation terminal and emf emitter providing dynamic optimization of emission and therapeutic effect and remote therapeutic system

A cell excitation terminal and a therapeutic system using customized electromagnetic (EM) waves varying dynamically with time for excitation include one or more EM wave generators, each of the EM wave generators is connected to a central processing unit (CPU), and the CPU controls, according to a signal detected by a human body status detection device, the EM wave generator to send EM waves corresponding to a detected status or subject patient. The therapeutic system can perform remote management. A remote server optimizes and updates therapeutic waveforms of a patient constantly according to a therapeutic effect of the patient, thereby improving the therapeutic effect constantly.

Vacuum prosthesis with force sensing member

A prosthetic device includes a socket assembly defining a cavity and configured to receive a portion of a residual limb of a user within the cavity, a force sensing member configured to detect forces applied to the residual limb at a plurality of locations about the portion of the residual limb and generate signals based on the detected force, a vacuum system in fluid communication with the socket and configured to control an amount of vacuum applied to the cavity, and a controller coupled to the force sensing member and the vacuum system. The controller is configured to receive the signals from the force sensing member and control operation of the vacuum system during use of the prosthetic device by the user based at least in part on the signals received from the force sensing member.

Movement Monitoring Device For Action Sports, And Associated Methods

A movement monitoring device (MMD) for action sports has a detector for sensing motion associated with action sports, a processor for processing data from the detector to determine one or more movement metrics, and a communications port for wirelessly relaying the movement metrics to a remote location. A method collects motion data within action sports, including: detecting motion of a person or object engaged in action sports; determining one or more events associated with the motion; and wirelessly relaying the events to a remote network. One MMD for action sports is formed within a cell phone having a detector for sensing motion associated with action sports and a processor for processing data from the detector to determine one or more movement metrics for (a) display to a person using carrying the cell phone during action sports or (b) relaying the movement metrics to an external network for review by others.

Method and System for Monitoring Nutritional Uptake as a Function of Microflora Intestinal Gas Levels

Systems and methods for monitoring nutritional uptake of an individual are disclosed. The method can include monitoring microflora intestinal gas concentration levels associated with a patient and adjusting the volume of nutrient provided by the patient with an artificial feeding device based at least in part on the microflora intestinal gas levels associated with the patient. A microflora intestinal gas sensor can be used to monitor the microflora intestinal gas associated with the patient. The microflora intestinal gas sensor can monitor the microflora intestinal gas in a patient's exhaled breath or in the patient's digestive tract. The microflora intestinal gas sensor be included as part of an enteral feeding system at the distal end or outside end of an enteral feeding tube. Systems and methods for monitoring nutritional uptake of an infant based on microflora intestinal gas levels associated with the infant are also disclosed.

Method for assessing the susceptibility of a human individual suffering from a psychiatric or neurological disorder to neuromodulation treatment

Method for assessing the susceptibility of a human individual suffering from a psychiatric or neurological disorder, in particular with depressed mood as a predominant feature, to neuromodulation treatment, in particular repetitive Transcranial Magnetic Stimulation (rTMS), the method comprising: a) Providing a dataset comprising electroencephalographic (EEG) activity and Event Related Potentials (ERP) data of said human individual; b) Assessing the susceptibility of said human individual to neuromodulation treatment based on said dataset.

Optogenetic magnetic resonance imaging

Disclosed herein are systems and methods involving the use of magnetic resonance imaging and optogenetic neural stimulation. Aspects of the disclosure include modifying a target neural cell population in a first region of a brain to express light-responsive molecules. Using a light pulse, the light-responsive molecules in the target neural cell population are stimulated. Multiple regions of the brain are scanned via magnetic resonance imaging. The scans allow for observation of a neural reaction in response to the stimulation in at least one of the multiple regions of the brain.

Reagents and methods for modulating cone photoreceptor activity

The present invention provides reagents and methods for modulating cone photoreceptor activity, and devices for assessment of cone photoreceptor activity.

Glycemic health metric determination and application

Disclosed are methods, apparatuses, etc. for determination and application of a unidimensional metric for assessing a patient's glycemic health. In one particular implementation, a computed metric may be used to balance short-term and long-term risks associated with a particular therapy. In another implementation, a computed unidimensional metric may be used to balance risks of hyperglycemia and hypoglycemia.

Patient monitoring device

A patient monitoring device to be worn on a limb of a patient. Some embodiments of the patient monitoring device include at least one sensor assembly configured to detect a measurement indicating a distance around the patient's limb and a communications subassembly configured to transmit the measurement to at least one external computing device. Other embodiments of the patient monitoring device include at least one sensor assembly configured to detect a measurement indicating a distance around the patient's limb and at least one processor configured to detect whether the distance around the patient's limb has increased indicating edema. Some embodiments include an accelerometer configured to detect device orientation and/or patient activity information. The patient activity information may be analyzed by an external computing device and/or the patient monitoring device to determine whether the patient's activity level has declined indicating a medical problem.

Imaging-guided joint injection system

Systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, an intra-articular space, include a handpiece assembly having a proximal end and a distal end, a needle extending from the distal end of the handpiece assembly, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medications, formulations and/or other fluids or materials contained within vials that are secured to the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.

System for tandem bed communication

This disclosure concerns a communication system adapted to communicate between a handheld remote control and a first adjustable bed controller of a first adjustable bed facility, and a second communication system adapted to communicate between the first adjustable bed controller of the first adjustable bed facility and a second adjustable bed controller of a second adjustable bed facility.

Pain tracking and management device

A system, method and apparatus for real time measurement and monitoring of various personal health parameters including controlled delivery of drugs/medications by intelligent pump appliances, intelligent inhalation appliances and intelligent skin patch appliances used in a standalone manner or in a wired or wireless networked configuration, in conjunction with various peripheral devices, other intelligent appliances, servers, RF ID Tags and stationary/mobile devices. The intelligent appliances relate to the measurement, monitoring and delivery of insulin/other drugs for the treatment of diabetes and other diseases. The method also additionally includes the application of intelligent appliances for pain management including visualization of organs and body locations exhibiting pain.

System and Method for Detecting a Clinically-Significant Pulmonary Fluid Accumulation Using an Implantable Medical Device

Techniques are provided for detecting a clinically-significant pulmonary fluid accumulation within a patient using a pacemaker or other implantable medical device. Briefly, the device detects left atrial pressure (LAP) within the patient and tracks changes in the LAP values over time that are indicative of possible pulmonary fluid accumulation within the patient. The device determines whether the changes in LAP values are sufficiently elevated and prolonged to warrant clinical intervention using, e.g., a predictor model-based technique. If the fluid accumulation is clinically significant, the device then generates warning signals, records diagnostics, controls therapy and/or titrates diuretics. False positive detections of pulmonary edema due to transients in LAP are avoided with this technique. Pulmonary artery pressure (PAP)-based techniques are also described.

Robotically-controlled surgical instrument with force-feedback capabilities

A surgical instrument. Various embodiments of the surgical instrument include an end effector that has a moveable cutting implement. A main drive shaft assembly operably interfaces with the end effector for transmitting an actuation motion to the movable cutting implement therein. A gear drive train is connected to the main drive shaft assembly. The gear drive train is actuated by a motor that is configured to receive control signals from a robotic system. Various embodiments include a sensor arrangement that operably interfaces the end effector to communicate forces experienced by the end effector to the robotic system.

Systems for remote generation of electrical signal in tissue based on time-reversal acoustics

A time-reversal acoustics system includes a transmitter configured to send a high intensity acoustic waveform signal focused on an implantable receiver. The receiver includes a piezoelectric transducer configured to convert received acoustic energy to an electrical signal used to energize an internal electrical circuit. Such circuit may be used to operate at least one tissue stimulating electrode, at least one sensor such as an ECG sensor, charge an internal battery or perform another useful function. The system of the invention may be used as a wireless cardiac pacemaker or a neurostimulator.

Test phantom for tomographic imaging and notably for breast tomosynthesis

A test phantom for tomographic imaging, the phantom comprising an assembly of elementary structures defining a 3D mesh, wherein each elementary structure comprises a chief constituent material corresponding to an X-ray attenuation simulating a glandularity, wherein the elementary structures are in at least two types of chief constituent materials corresponding to different X-ray attenuations.

Sleep element for improving the sleep of a person

The invention relates to a sleep element ( 1 ) like a heating blanket for improving the sleep of a person. The sleep element comprises a property determination unit ( 2, 5 ) for determining a property of a person, a thermal energy unit ( 3 ) for transferring thermal energy to or away from the person, and a thermal energy control unit ( 4 ) for controlling the thermal energy unit depending on the determined property of the person. Since the sleep element comprises the property determination unit, the thermal energy unit, and the thermal energy control unit, the temperature of the person can be controlled depending on a determined property of the person, while the person is sleeping, such that the sleep of the person is improved. Moreover, the temperature control can simply be used within a bed by placing the sleep element in the bed. The handling of the temperature control is therefore very simple.

Particle beam therapy system

The objective is to eliminate the effect of the hysteresis of a scanning electromagnet and resume high-accuracy beam irradiation from an irradiation position where it has been interrupted, even in the case where emergency-stop processing is performed during therapy. There are provided an irradiation management apparatus that controls a scanning electromagnet; and an interlock information inputting device that generates an interlock signal for stopping irradiation of the charged particle beam, when a contingency occurs. When irradiation of the charged particle beam is resumed, the irradiation management apparatus performs idle operation in which the scanning electromagnet is controlled, with the charged particle beam unirradiated, from a start step, which is situated prior to a stop step and is different from the initial step in actual irradiation, to the stop step, and then irradiates the charged particle beam from the desired irradiation position coordinates corresponding to the stop step.

Feedback Systems and Methods for Communicating Diagnostic and/or Treatment Signals to Enhance Obesity Treatments

Feedback systems and methods communicate implanted sensor-based feedback signals to promote behavior modifications that ameliorate obesity and other eating disorders. The system and methods described may also be applicable to any treatment in which presenting feedback regarding patients' eating and exercise habits is desired. The present invention provides a method and system for treating a patient by collecting ingestion and exercise information about the patient from an implanted sensor and communicating the collected information to the patient, his or her physician and/or other health care providers. In some embodiments, stimulation of the patient's stomach is also provided to reduce caloric intake. In some embodiments, the collected data is transmitted to a central server. Further embodiments may provide access to additional information in conjunction with the collected patient information, such as a calorie database, an exercise planner, and so forth, with the data optionally being used within a social networking system.

Noninvasive cutaneous blood flow assessment as a response predictor for visible light therapy on segmental vitiligo

Visible light is a treatment option for Segmental Vitiligo (SV), and visible light-induced repigmentation is associated normalization of sympathetic. Currently it is difficult to predict individual patient's response to visible light therapy. Therefore, the present invention uses the Laser Doppler Flowmeter to serve as a response predictor for visible light on treating SV. The present invention recruited 14 Segmental Vitiligo patients for evaluating clinical information. FirstLaser Doppler Flowmeter was used to evaluate the cutaneous blood flow of SV lesion and contralateral normal skin, and then treated them with visible light irradiate, cold-stress, rewarmed, and recorded the change of skin blood flow, finally the patients received regular visible light treatment for 3 months, and patients have a sign of repigmentation after the treatment.

Medical device

A modular medical device includes a core module housing. The core module housing includes a treatment module interface configured to couple to any one of a plurality of treatment modules, and each of the plurality of treatment modules includes a treatment assembly configured to apply a medical treatment. The core housing module contains one or more processing devices coupled to the treatment module interface and configured to determine which particular treatment module, from the plurality of treatment modules, is coupled to the treatment module interface. The one or more processing devices are configured to select, based on the determination, a set of control instructions for the particular treatment module from a plurality of control instructions, and control the particular treatment module using the selected control instructions such that the treatment assembly of the particular treatment module applies the medical treatment for which the treatment assembly is configured.

Device, Methods, and Control for Sonic Guidance of Molecules and Other Material Utilizing Time-Reversal Acoustics

The present invention provides for a method of controlling mass movement of fluid material within a field of interest comprising using time reversal acoustic focusing. The time reversal acoustic focusing can be is used for simultaneous spatial and temporal focusing of acoustic energy to control the duration of localization and/or direction of movement of material within tissue or liquid within tissue. Both delivery of material and persistence with respect to target locations can be enhanced by focusing of sonic waveforms or transmissions towards targeted areas in a field of interest, such as within a patient.

Automated Caregiving Device with Prompting Based on Caregiver Progress

A device for assisting a caregiver in delivering therapy to a patient, the device comprising a user interface configured to deliver prompts to a caregiver to assist the caregiver in delivering therapy to a patient; at least one sensor configured to detect the caregiver's progress in delivering the therapy, wherein the sensor is other than an electrode in an electrical contact with the body; a memory in which a plurality of different prompts are stored; a processor configured to determine which of the different prompts should be selected for delivery based on the progress detected by the sensor.

Bodily fluid composition analyzer with disposable cassette

Disclosed is an apparatus for analyzing the composition of bodily fluid. The apparatus can include a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient and a pump unit in operative engagement with the fluid handling network. The pump unit can have an infusion mode, in which the pump unit is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode, in which the pump unit is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus can include a spectroscopic analyzer positioned to analyze at least a portion of the sample; a processor in communication with or incorporated into the spectroscopic analyzer; and stored program instructions executable by the processor to obtain measurements of two or more properties of the sample.

ECG Artifact Reduction System

An ECG signal processing system which removes the CPR-induced artifact from measured ECG signals obtained during the administration of CPR.

Nerve treatment system

In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another. In some examples, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents or the agents are enhanced by the energy sources.

Drug Delivery Method Via Brain Extracellular Space and a Device Thereof

The present invention relates to a method for drug delivery via brain extracellular space (ECS). It includes putting head of patient in an imaging apparatus; generating dynamic images of the brain via the imaging apparatus; delivering drugs into brain ECS of the patient according to the dynamic images and the drugs get to the therapeutic target by simple diffusion along concentration gradient. The present invention also relates to a device for drug delivery via brain ECS. Basing on the self-diffusion delivery (SDD) of drugs in brain ECS, the present invention can deliver drug into the ECS of the brain's relatively safe area in low speed, with small amounts of doses and without extra stress. Therefore, the present invention can reduce delivery time and dose of drugs, relieve injection pressure, decrease damages on normal brain tissue, and reduce the cost of treatment observably.

Apparatus and method for treating obstructive sleep apnea

The present invention describes an apparatus, a system and a method for the treatment of obstructive sleep apnea. The treatment involves monitoring the position of the tongue and/or the force exerted by the tongue and electrical stimulation of the hypoglossal nerve to move the tongue into an anterior position or to maintain the tongue in an anterior position.

Health monitoring appliance

A heart monitoring system for a person includes one or more wireless nodes; and a wearable appliance in communication with the one or more wireless nodes, the appliance monitoring vital signs. Other implementations can monitor heart rate, heart rate variability, respiratory rate, fluid status, posture and activity.

Controlled titration of neurostimulation therapy

Described herein are methods and devices that utilize electrical neural stimulation to treat heart failure by modulating a patient's autonomic balance in a manner that inhibits sympathetic activity and/or augments parasympathetic activity. Because other therapies for treating heart failure may also affect a patient's autonomic balance, a device for delivering neural stimulation is configured to appropriately titrate such therapy in either an open-loop or closed-loop fashion.

Method of diagnosing, prognosing and monitoring alzheimer's disease

The present invention provides a system and method for diagnosing, monitoring or prognosing Alzheimer's disease using at least one sensor comprising carbon nanotubes coated with cyclodextrin or derivatives thereof and/or at least one sensor comprising metal nanoparticles coated with various organic coatings in conjunction with a learning and pattern recognition algorithm.

Stimulatory effect estimation device, sleep depth estimation device, stimulatory effect estimation method, and vehicle control device

A stimulatory effect estimation device includes a stimulus generator 3 which applies a stimulus to a back seat passenger, an electroencephalogram 2 which measures the brain waves of the back seat passenger, a memory 4 , and an ECU 5 which specifies the brain wave indexes of stimulatory effects which surface in response to the stimuli both when the passenger is awake and when the passenger is asleep from the brain waves measured by the electroencephalogram 2 when a stimulus is applied from the stimulus generator 3 while the passenger is awake and the brain waves measured by the electroencephalogram 2 when a stimulus is applied from the stimulus generator 3 while the passenger is asleep. The ECU 5 estimates stimulatory effects when the passenger is asleep from stimulatory effects when the passenger is awake using a conversion model for converting the stimulatory effect when the passenger is awake and the stimulatory effects when the passenger is asleep on the basis of the brain wave indexes which surface when the same stimulus is applied when the passenger is awake and when the passenger is asleep, and selects a stimulus which is applied to the back seat passenger on the basis of the relationship between the stimulatory effects and the changes in sleep depth.

Non-invasive, vibrotactile medical device to restore normal gait for patients suffering from peripheral neuropathy

Provided is a comfortable and discrete device wearable by a patient to restore balance and gait. The device re-establishes the sensorimotor loop by providing the patient with a secondary signal to healthy nerves around the knee to alert the patient that the patient's heel has just struck the ground. In this regard, the device monitors the patient's leg movements to detect when the patient's heel strikes the ground and sends the secondary signal, i.e., vibrotactile stimulation, in response to the detected heel strike. The central nervous system incorporates the new signal and the motor system responds as if there is not loss of sensation in the foot and returns to its normal gait.

Goal-directed fluid therapy

A method includes setting a hydration goal and administering a diuretic to the patient to induce increased urine flow and collecting urine expelled by the patient. The amount of urine expelled by the patient is determined based on the collected urine. The patient is infused with fluid from a fluid source. The amount of fluid infused into the patient is determined. Diuresis is induced by automatically and continuously adjusting the amount of fluid infused into the patient from the fluid source to meet the hydration goal based on the set hydration goal, the determined amount of urine expelled by the patient and the fluid infused.

Dosage regimen of an s1p receptor modulator

S1P receptor modulators are administered following a dosage regimen providing a positive benefit-risk profile.

Advanced analyte sensor calibration and error detection

Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

Diagnostic Method

This is a diagnostic method to determine and predict disease and observe the development of a disease by using a dual-arm blood pressure monitor that measures the balance of relationship between human organs and functions. This method uses the dialectical theory of “the balance of yin and yang’ in traditional Chinese medicine and is combined with modern blood pressure measuring tools, and is able to forecast and observe the process and effects of treatment of a disease. The method makes it possible for efficacy of Chinese medicine diagnosis go out of fuzzy situation, and is a breakthrough in disease forecast, diagnosis, and treatment which is also considered a significant contribution to Western medicine for diagnostics.

Energetic modulation of nerves

A system to modulate an autonomic nerve in a patient utilizing transcutaneous ultrasound energy delivery includes a processor comprising an input for receiving information regarding energy and power to be delivered to a treatment region containing the nerve, and an output for outputting a signal, wherein the processor is configured to determine a position of a reference target from outside the patient to localize the nerve relative to the reference target, a therapeutic energy device comprising a transducer for delivering ultrasound energy from outside the patient, a controller to control an aiming of the transducer based at least in part on the signal from the processor, and an imaging system coupled to the processor or the therapeutic energy device.

Surgically Implantable Electrodes

The present inventions provide for paddle lead electrodes that are capable of performing peripheral nerve stimulation, thereby modulating, controlling and/or reducing neuropathic pain in a patient, that are also surgically implantable, and that will remain fixed in place at the site of implantation when in use. More specifically, one or more embodiments of the electrodes of the present inventions are capable of being surgically implanted underneath a sheath of protective connective tissue that covers electrically excitable tissues and are adapted to electrically stimulate those tissues. Electrodes contemplated by embodiments of the present inventions are particularly well suited for perineurial implantation. Embodiments of the present inventions include methods of use associated with the electrodes.

Method and apparatus for real time monitoring of tissue layers

The disclosed method and apparatus employ ultrasound beams to monitor the tissue type composition of body tissue that is to be treated and the temperature at each body tissue type or layer in real time. Additionally, the disclosed method and apparatus also provides ultrasound-based thermo-control of an aesthetic body treatment session.

Systems for intravenous drug monitoring

A system for monitoring a concentration of an anesthetic drug using a patient's breath is provided. The system comprises a sampling subsystem for processing the patient's breath to form a breath sample, one or more sensors to measure drug concentration in the breath sample, one or more sensors to measure a concentration of gases in the breath sample; and one or more microprocessors for determining a concentration of the drug in a plasma of the patient using a transfer function and the concentration of the drug in the breath sample. A system for monitoring propofol concentration in patient's breath sample is also provided.

Methods for detecting enhanced risk of opioid-induced hypoxia in a patient

Methods for detecting enhanced risk of opioid-induced respiratory dysfunction in patients with normal levels of oxygen saturation. The method may comprise: (1) assaying blood of the patient for a normal level of oxygen saturation; (2) measuring the patient's respiration rate at rest for a normal rate; and (3) correlating the normal level of oxygen saturation and the normal rate of respiration with enhanced risk of opioid-induced respiratory dysfunction if: (a) the patient is at an altitude of about 1000 feet above sea level or greater; or (b) the patient's oxygen saturation level is normal but no greater than about 95%; or (c) the patient received prior dosing with intravenous opioid and is converted to dosing with an oral opioid. The method may further comprise administering opioids to a patient after detecting whether there is an enhanced risk of opioid-induced respiratory dysfunction.

Vessel pulse wave measurement system conducting vessel pulse wave measurement by obtaining pulsation waveform of blood vessel

A vessel pulse wave measurement system performs vessel pulse wave measurement using an optical probe circuit provided with an optical probe including a light emitting element and a light receiving element, a drive circuit, and a detection circuit. A measurement device directly and synchronously feeds back an electrical signal from the optical probe to the drive circuit as a drive signal to generate a self-oscillation signal from the detection circuit, and measures the self-oscillation signal as a vessel pulse wave signal. A controller controls an operating point of at least one of the detection circuit and the drive circuit such that the self-oscillation signal substantially reaches a maximum level thereof.

Respiratory muscle endurance training device and method for the use thereof

A respiratory muscle endurance training device (RMET) includes a chamber and a patient interface. In one implementation, one or both of a CO 2 sensor or a temperature sensor can be coupled to the chamber or patient interface to provide the user or caregiver with indicia about the CO 2 level in, or the temperature of, the chamber or patient interface, and/or the duration of use of the device. In another implementation, the RMET may have a fixed volume portion adjustable to contain a measured portion of a specific patient's inspiratory volume capacity. Methods of using the device are also provided.

Method and apparatus for monitoring sleep apnea severity

Disclosed embodiments include a method and an apparatus for monitoring sleep apnea severity that comprise: (a) analyzing an oxygen saturation signal to extract a plurality of time-domain and frequency-domain metrics; (b) calculating an oxygen saturation-based Apnea Hyponea Index (AHI) by employing a predetermined functional mapping between said metrics and polysomnography (PSG)-based AHI; and (c) displaying an oxygen saturation-based AHI to enable a specialist to monitor sleep apnea severity without requiring PSG. According to a particular embodiment, the oxygen saturation signal is nocturnal oxygen saturation and the functional mapping is a multilinear regression model (MLR) or a multilayer perceptron network (MLP).

Transducer mountings and wearable monitors

A transducer mounting comprising a compliant elongate support member having a skin engaging surface, adhering means to adhere the skin engaging surface to a wearer's head, and a plurality of transducers longitudinally spaced on the skin engaging surface. A wearable monitor comprising adhering means for adhering the wearable monitor to skin, a skin-facing surface with a transducer thereon for either or both stimulating a physiological response and measuring a physiological parameter, and display means or audio output means integral to the wearable monitor for displaying a signal related to a measured physiological parameter on the wearable monitor or transmitting a sound related to a measured physiological parameter from the wearable monitor, respectively.

Integrated delivery device for continuous glucose sensor

Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.

Biometric healthcare data system

A biometric healthcare data system has biometric data collection stations and a network management system. Each station has several biometric data measurement devices including a bioelectrical impedance analysis system. Each station has a gateway that connects to the devices and that connects the station through the internet to the network management system. The network management system has a communications manager that tracks the stations, a content manager that provides content to the stations and a data manager that retrieves and stores data from the data collection stations.

System and method for spo2 instability detection and quantification

The disclosed embodiments relate to a system and method for analyzing data. An exemplary method comprises the acts of receiving data corresponding to at least one time series, and computing a plurality of sequential instability index values of the data. An exemplary system comprises a source of data indicative of at least one time series of data, and a processor that is adapted to compute at least one of a plurality of sequential instability index values of the data.

Medication management and reporting technology

Medication management and reporting technology, in which output from at least one sensor configured to sense physical activity in a building in which medication of a patient is located is monitored and a determination is made to capture one or more images of the medication based on the monitoring. A camera is used to capture an image of the medication and the captured image is analyzed to detect a state of the medication. Information regarding a schedule by which the medication should be taken by the patient is accessed and an expected state of the medication is determined. The detected state is compared with the expected state and a determination is made that the patient has departed from the schedule based on the comparison revealing that the detected state does not match the expected state. A message indicating the departure from the schedule is sent based on the determination.

Systems and methods for providing biometric related to performance of a physical movement

A biometric feedback system for providing biometric feedback to a subject while the subject performs a controlled physical movement includes an applied-force-recording interface and at least one controller electrically coupled to the applied-force-recording interface. The at least one controller receives applied force from the subject during the controlled physical movement and the applied-force-recording interface records data related to the applied force. The biometric feedback system also includes a dynamic surface electromyograph (“sEMG”) device that detects muscle tension along at least one muscle group of the subject while the subject performs the controlled physical movement and records data related to the muscle tension. A hub receives and processes data from the applied-force-recording interface and the dynamic sEMG device. A visual display displays the processed data from the hub.

Power management in a data-capable strapband

Embodiments of the invention relates generally to electrical and electronic hardware, computer software, wired and wireless network communications, and computing devices, and more specifically to structures and techniques for managing power generation, power consumption, and other power-related functions in a data-capable strapband. Embodiments relate to a wearable band including sensors, a controller coupled to the sensors, an energy storage device, a power port configured to receive power and control signals, and a power manager. The power manager includes at least a transitory power manager configured to control an application of power to one or more components of the wearable band in one or more power modes. The band can be configured as a wearable communications device and sensor platform.

Method and system for detecting electrophysiological changes in pre-cancerous and cancerous breast tissue and epithelium

A method and system are provided for determining a condition of a selected region of epithelial and stromal tissue in the human breast. A plurality of measuring electrodes are used to measure the tissue and transepithelial electropotential of breast tissue. Surface electropotential and impedance are also measured at one or more locations. An agent may be introduced into the region of tissue to enhance electrophysiological characteristics. The condition of the tissue is determined based on the electropotential and impedance profile at different depths of the epithelium, stroma, tissue, or organ, together with an estimate of the functional changes in the epithelium due to altered ion transport and electrophysiological properties of the tissue. Devices for practicing the disclosed methods are also provided.

Ventilation mask with integrated piloted exhalation valve

In accordance with the present invention, there is provided a mask for achieving positive pressure mechanical ventilation (inclusive of CPAP, ventilator support, critical care ventilation, emergency applications), and a method for a operating a ventilation system including such mask. The mask of the present invention includes a piloted exhalation valve that is used to achieve the target pressures/flows to the patient. The pilot for the valve may be pneumatic and driven from the gas supply tubing from the ventilator. The pilot may also be a preset pressure derived in the mask, a separate pneumatic line from the ventilator, or an electro-mechanical control. The mask of the present invention may further include a heat and moisture exchanger (HME) which is integrated therein.

Health monitoring appliance

A heart monitoring system for a patient includes one or more wireless nodes forming a wireless network; a wearable appliance having a wireless transceiver to communicate with the one or more wireless nodes; and an analyzer to determine vital signs, the analyzer coupled to the wireless transceiver to receive patient data over the wireless network.

Visceral fat measurement device

A visceral fat measurement device includes a current-applying electrode pair including a first current-applying electrode and a second current-applying electrode, and a voltage measurement electrode pair including a first voltage measurement electrode and a second voltage measurement electrode. The current-applying electrode pair is arranged on a projected line obtained by projecting the body trunk axis of a measured body to the body surface of an abdominal part of the measured body. The first and second current-applying electrodes are separated from each other at a predetermined interval determined so that a current path connecting the first current-applying electrode, visceral fat, and the second current-applying electrode is formed. The voltage measurement electrode pair is arranged between the first and second current-applying electrodes in a direction along the body trunk axis of the measured body.

System and method for evaluating physiological parameter data

Embodiments disclosed herein may include systems and methods for evaluating physiological parameter data. Embodiments of methods may include monitoring a patient to produce a signal comprising a sequence of numerical values for a physiological parameter over a time period, calculating an index from the signal, comparing the index to a reported index, and if the index is greater than the reported index, setting the reported index to the value of the index. Embodiments of methods may include calculating a modulation of the signal, comparing the modulation to a previous valise of the modulation to identity a trend in the modulation and if the trend corresponds to an undesirable condition, using a first function, to increase the reported index. Embodiments of methods may include providing an indication of a physiological status based on the reported index.

Systems and Methods for Alcohol Consumption Monitoring

Various embodiments of the present inventions are related to monitoring physical characteristics of a monitored individual including, but not limited to, alcohol consumption by the monitored individual.

Electronic device and method for assisting correction of walking styles

An electronic device receives real-time data in relation to plantar pressures of a user. The real-time data is detected by pressure sensors, which is installed within insoles in a pair of shoes of the user, and sent to the electronic device via a wireless communication module installed in the insoles or the shoes. The electronic device then generates a real-time image in relation to real-time plantar pressure distributions of the user according to the real-time data, compares the real-time image with a pre-stored image stored in a storage device, and determines if a comparison result satisfies a preset requirement. The pre-stored image is in relation to standard plantar pressure distributions produced from a standard walking style. If the comparison result does not satisfy the preset requirement, the electronic device displays alert information via an output device to prompt the user to adjust the user's walking style.

Devices, systems and methods to analyze evoked responses to pre-pacing pulses to predict imminent vt/vf, estimate ischemic burden and/or characterize electrical substrates

Described herein are implantable systems, and methods for use therewith, to predict whether ventricular tachycardia (VT) or ventricular fibrillation (VF) is imminent, estimate ischemic burden and/or characterize an electrical substrate of the LV chamber. For each of a plurality of cardiac cycles, a pacing vector comprising a first set of electrodes is used to deliver a pre-pacing pulse at a site within the LV chamber (wherein the pre-pacing pulse is delivered prior to an intrinsic activation of the LV chamber), and a sensing vector comprising a second set of electrodes is used to detect an evoked response to the pre-pacing pulse. The detected evoked responses to the pre-pacing pulses are analyzed, and results of the analysis are used predict whether VT or VF is imminent, estimate ischemic burden and/or characterize an electrical substrate of the LV chamber.