Настройки

Укажите год
-

Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

Подробнее
-

Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

Подробнее

Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Укажите год
Укажите год
Применить Всего найдено 21. Отображено 21.
29-06-2015 дата публикации

Pharmaceutical compositions having anti-metastasis activity comprising extract of bambusae caulis in taeniam

Номер: KR0101532307B1
Автор: 마진열, 김애영, 김태수, 임민주, 임남희, 정영필
Принадлежит: 한국 한의학 연구원

... 본 발명은 죽여 추출물을 유효성분으로 포함하는, 암전이 억제용 약학 조성물 및 암전이 억제용 식품 조성물에 관한 것이다. 본 발명의 죽여 추출물을 포함하는 조성물은 세포 독성이 낮고 부작용이 거의 없는 장점을 보유하면서도 전이를 억제할 수 있으므로, 전이 또는 전이 관련 질환의 치료제, 또는 전이 또는 전이 관련 질환을 예방 또는 개선할 수 있는 기능성 식품 제제로 유용하게 이용할 수 있다.

Подробнее
Номер записи: 1
16-01-2019 дата публикации

신규한 리그난 유도체 및 이의 용도

Номер: KR1020190005280A
Автор: 마진열, 이위, 이정진, 조원경, 임남희
Принадлежит:

... 본 발명은 신규한 리그난 유도체 또는 이의 약학적으로 허용 가능한 염, 또는 이의 제조방법, 또는 이를 유효성분으로 함유하는 혈전성 질환의 예방 또는 치료용 약학적 조성물, 또는 혈전성 질환의 예방 또는 개선용 건강기능식품 조성물에 관한 것이다. 본 발명에 따른 신규한 리그난 유도체 또는 이의 약학적으로 허용 가능한 염을 포함하는 조성물은 혈소판의 응집 현상을 효과적으로 억제시킴으로써 혈전성 질환의 예방 또는 치료에 우수한 효과가 있다. 따라서, 상기 조성물은 혈전성 질환의 예방 또는 치료용 약학적 조성물, 또는 혈전성 질환의 예방 또는 개선용 건강기능식품 조성물에 유용하게 적용할 수 있다.

Подробнее
Номер записи: 2
26-10-2017 дата публикации

COMPOSITION FOR PREVENTING OR TREATING DRY EYE SYNDROME COMPRISING MAPLE LEAF EXTRACT

Номер: WO2017183924A1
Автор: MA, Jin Yeul, OH, You Chang, YIM, Nam Hui, YOO, Jae Myung, CHO, Won Kyung, HWANG, Youn Hwan, KIM, Yeoun-Hee, OH, Tae Woo, PARK, Eun Hee, PARK, Kwang Il
Принадлежит:

The present invention relates to a composition for preventing or treating dry eye syndrome comprising a maple leaf extract and, specifically, to a pharmaceutical composition for preventing or treating dry eye syndrome comprising a maple leaf extract as an active ingredient, a method for preventing or treating dry eye syndrome using the pharmaceutical composition, and a food composition and a cosmetic composition for preventing or ameliorating dry eye syndrome comprising a maple leaf extract as an active ingredient. The maple leaf extract of the present invention has an effect of being capable of preventing, ameliorating, and treating dry eye syndrome to a degree similar or superior to an existing drug known as a therapeutic agent of dry eye syndrome. In addition, the composition of the present invention is derived from a natural substance, and thus can be used safely without any side effects for the prevention, treatment and amelioration of dry eye syndrome.

Подробнее
Номер записи: 3
29-10-2018 дата публикации

LACTIC ACID BACTERIA FERMENTED PRODUCT OF SAGUNJATANG HAVING PROTECTIVE ACTIVITY FOR CRANIAL NERVE CELLS AND USES THEREOF

Номер: KR1020180117251A
Автор: MA, JIN YEUL, GU, MIN JUNG, YIM, NAM HUI, PARK, HEE RA, CHO, WON KYUNG, HWANG, YOUN HWAN, OH, YOU CHANG
Принадлежит:

The present invention relates to a lactic acid bacteria fermented product of Sagunjatang (Korean medicine of four different herbs) having a protective activity for cranial nerve cells and uses thereof, and more particularly, to a pharmaceutical composition and a health functional food composition for preventing or treating cranial nerve diseases including a lactic acid bacteria fermented product of an extract of Panax ginseng, Atractylodes japonica, Poria coco, and Glycyrrhiza glabra, and a preventing or treating method. Since the extract including Panax ginseng, Atractylodes japonica, Poria coco, and Glycyrrhiza glabra, that is, a lactic acid bacteria fermented product of Sagunjatang in which Sagunjatang is fermented with Lactobacillus plantarum, shows excellent protective effect for cranial nerve cells, and thus can be usefully used for preventing or treating cranial nerve diseases. COPYRIGHT KIPO 2018 ...

Подробнее
Номер записи: 4
20-05-2010 дата публикации

PHARMACEUTICAL COMPOSITION FOR SUPPRESSING DNA METHYLTRANSFERASE, CONTAINING ARYLOXYACETYL-BASED COMPOUNDS AS ACTIVE INGREDIENTS

Номер: WO2010056048A3
Автор: LEE, Kyeong, WON, Misun, LEE, Jung Joon, CHUNG, Kyung-Sook, PARK, Song-Kyu, KWON, Byoung-Mog, YIM, Nam-Hui, KANG, Jung Eun, JIN, Yinglan, XIA, Yan, KIM, Bo Yeon, AHN, Jong Seog
Принадлежит:

The present invention relates to a pharmaceutical composition for suppressing DNA methyltransferase, containing the aryloxyacetyl-based compounds expressed in chemical formula 1 as active ingredients. The composition of the present invention can be used as a therapeutic agent for tumors, neurological brain diseases, hematologic diseases, and epigenetic diseases caused by DNA hypermethylation. Further, the present invention provides uses of aryloxyacetyl-based compounds expressed in chemical formula (1) mentioned below or pharmaceutically acceptable salts thereof to produce a DNA methyltransferase inhibitor or a DNA methylation inhibitor. The present invention provides a method for treating diseases caused by DNA hypermethylation by administering aryloxyacetyl-based compounds (LW6) expressed in chemical formula 1, or pharmaceutically acceptable salts thereof, to mammals (including humans) that require DNA methytransferase inhibition or DNA methylation inhibition.

Подробнее
Номер записи: 5
13-07-2015 дата публикации

Composition for prevention or treatment of thrombotic diseases comprising extracts or fractions of Playtcodon grandiflorum

Номер: KR0101536211B1
Автор: 마진열, 이정진, 임남희, 권혜은, 조원경, 김태수
Принадлежит: 한국 한의학 연구원

... 본 발명은 길경 추출물 또는 이의 분획물을 유효성분으로 함유하는 혈전성 질환의 예방, 치료 또는 개선용 약학적 조성물 또는 식품 조성물에 관한 것이다.

Подробнее
Номер записи: 6
20-05-2010 дата публикации

PHARMACEUTICAL COMPOSITION FOR SUPPRESSING DNA METHYLTRANSFERASE, CONTAINING ARYLOXYACETYL-BASED COMPOUNDS AS ACTIVE INGREDIENTS

Номер: WO2010056048A2
Автор: LEE, Kyeong, WON, Misun, LEE, Jung Joon, CHUNG, Kyung-Sook, PARK, Song-Kyu, KWON, Byoung-Mog, YIM, Nam-Hui, KANG, Jung Eun, JIN, Yinglan, XIA, Yan, KIM, Bo Yeon, AHN, Jong Seog
Принадлежит:

The present invention relates to a pharmaceutical composition for suppressing DNA methyltransferase, containing the aryloxyacetyl-based compounds expressed in chemical formula 1 as active ingredients. The composition of the present invention can be used as a therapeutic agent for tumors, neurological brain diseases, hematologic diseases, and epigenetic diseases caused by DNA hypermethylation. Further, the present invention provides uses of aryloxyacetyl-based compounds expressed in chemical formula (1) mentioned below or pharmaceutically acceptable salts thereof to produce a DNA methyltransferase inhibitor or a DNA methylation inhibitor. The present invention provides a method for treating diseases caused by DNA hypermethylation by administering aryloxyacetyl-based compounds (LW6) expressed in chemical formula 1, or pharmaceutically acceptable salts thereof, to mammals (including humans) that require DNA methytransferase inhibition or DNA methylation inhibition.

Подробнее
Номер записи: 7
12-01-2017 дата публикации

COMPOSITION FOR TREATING CORNEAL DISEASES OR CONJUNCTIVAL DISEASES

Номер: WO2017007273A1
Автор: MA, Jin Yeul, KIM, Jung Hyun, JEON, Jong Wook, OH, You Chang, CHO, Won Kyung, HWANG, Youn Hwan, YIM, Nam Hui, YOO, Jae Myung
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing and treating corneal diseases or conjunctival diseases, containing a maple tree leaf extract as an active ingredient. The maple tree leaf extract exhibits an effect of inhibiting hyperemia in the eyeball of which hyperemia has been induced and of inhibiting angiogenesis in the eyeball of which corneal damage has been induced, thereby being usable in a pharmaceutical composition for preventing and treating corneal diseases or conjunctival diseases.

Подробнее
Номер записи: 8
11-08-2015 дата публикации

Cosmetic composition for improving skin photoaging comprising Lespedeza cuneata LPC extract

Номер: KR0101543461B1
Автор: 정유석, 정희경, 최향자, 이종민, 임남희
Принадлежит: 재단법인 대구테크노파크, 주식회사 소리소

... 본 발명은 피부광노화 개선기능성 화장료 조성물에 관한 것으로, 더욱 상세하게는 야관문 추출물을 0.01∼30중량% 함유하는 피부 노화방지 및 주름개선용 화장료 조성물에 관한 것으로 야관문 추출물 및 야관문 추출물 함유 시제품을 제조하는 단계와; 상기 단계에서 얻은 야관문 추출물의 총 폴리페놀 및 플라보노이드를 정량하고 항산화효소 활성을 측정하는 단계와; 마우스모델로 피부광노화 유발실험을 시행하고 피부 홍반도, 유수분 함량을 측정하는 단계와; 상기 마우스모델의 조직검사를 하는 단계와; 상기 단계에서 얻은 조직에서 추출한 유전자를 RT-PCR로 증폭하여 발현량을 비교, 평가함으로써 달성하였으며 콜라겐 섬유의 재생, 항산화 효능, 피부주름 개선을 통하여 피부 노화를 방지하는 뛰어난 효과가 있다.

Подробнее
Номер записи: 9
07-10-2016 дата публикации

COMPOSITION FOR TREATING CORNEAL DISEASE OR CONJUNCTIVA DISEASE

Номер: KR101662720B1
Автор: MA, JIN YEUL, KIM, JUNG HYUN, JEON, JONG WOOK, OH, YOU CHANG, CHO, WON KYUNG, HWANG, YOUN HWAN, YIM, NAM HUI, YOO, JAE MYUNG
Принадлежит: KOREA INSTITUTE OF ORIENTAL MEDICINE

The present invention relates to a pharmaceutical composition for preventing and treating a corneal disease or a conjunctiva disease comprising an extract of maple leaves as a main component. The pharmaceutical composition exhibits an effect of suppressing congestion in the eyes induced to have eye congestion, and an effect of suppressing generation of new blood vessels in the eyes induced to have corneal damage, thereby being useful as a pharmaceutical composition for preventing and treating a corneal disease or a conjunctiva disease. COPYRIGHT KIPO 2016 (A1,A2) Before inducing eye congestion (B1,B2) After inducing eye congestion (CC) Eye congestion-induced group (DD) Low concentration group of EE (EE) Medium concentration group of EE (FF) High concentration group of EE (GG) Low concentration group of EW (HH) Medium concentration group of EW (II) High concentration group of EW ...

Подробнее
Номер записи: 10
17-08-2015 дата публикации

Pharmaceutical composition and functional food for prevention or treatment of cancer comprising herbal extracts

Номер: KR0101544470B1
Автор: 마진열, 김애영, 임남희, 임민주, 김태수, 정영필
Принадлежит: 한국 한의학 연구원

... 본 발명은 천연식물 유래의 혼합 약재 추출물을 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물 및 건강기능식품에 관한 것으로, 더욱 자세하게는 천궁, 방풍, 당귀, 작약, 연교, 박하엽, 마황, 망초, 대황, 석고, 길경, 황금, 백출, 산치자, 형개, 생강, 활석, 감초, 금은화, 음양곽, 원지 및 목향으로 구성된 혼합 약재의 추출물을 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물 및 건강기능식품에 관한 것이다. 이에 따른 혼합 약재 추출물은 암 세포에 대하여 효과적인 전이 억제, 세포 사멸 유도 및 세포 성장 억제 활성을 가짐으로써 암의 예방 또는 치료용 조성물로 약학적으로 이용 가능할 뿐 아니라 건강기능식품으로도 유용하게 이용될 수 있다.

Подробнее
Номер записи: 11
22-02-2019 дата публикации

뇌 신경세포 보호 활성을 갖는 사군자탕 유산균 발효물 및 이의 용도

Номер: KR0101951402B1
Автор: 마진열, 구민정, 임남희, 박희라, 조원경, 황윤환, 오유창
Принадлежит: 한국한의학연구원

... 본 발명은 뇌 신경세포 보호 활성을 갖는 사군자탕 유산균 발효물 및 이의 용도에 관한 것으로, 구체적으로 인삼, 백출, 복령 및 감초를 포함하는 추출물의 유산균 발효물을 포함하는 뇌 신경 질환의 예방 또는 치료용 약학적 조성물, 건강기능식품 조성물, 및 예방 또는 치료 방법에 관한 것이다. 상기 인삼, 백출, 복령 및 감초를 포함하는 추출물, 즉 사군자탕을 락토바실러스 플란타럼(Lactobacillus plantarum)으로 발효한 사군자탕 유산균 발효물은 우수한 뇌 신경세포 보호 효과를 나타내므로, 상기 발효물을 포함하는 본 발명의 조성물은 뇌 신경 질환의 예방 또는 치료에 유용하게 사용될 수 있다.

Подробнее
Номер записи: 12
14-06-2018 дата публикации

COMPOSITION CONTAINING MAPLE TREE LEAF EXTRACT OR FRACTIONS THEREOF FOR PREVENTING OR TREATING INFLAMMATORY OCULAR DISEASES

Номер: WO2018106009A1
Автор: MA, Jin Yeul, KIM, Yeoun-Hee, OH, Tae Woo, PARK, Eun Hee, CHO, Won Kyung, YIM, Nam Hui, OH, You Chang, GU, Minjung
Принадлежит:

The present invention relates to: a pharmaceutical composition containing maple tree leaf extract or fractions thereof for preventing or treating inflammatory ocular diseases; a method for treating the diseases comprising a step of administering the composition into the eye of an individual; a quasi-drug composition; a composition for an eye makeup additive; a functional health food composition; and an animal feed composition.

Подробнее
Номер записи: 13
17-08-2015 дата публикации

Composition for Prevention or Treatment of Dental Caries Comprising Extract of Gentianae macrophyllae Radix

Номер: KR0101544939B1
Автор: 마진열, 임남희, 정윤희, 이주혜, 이지혜, 김홍익, 유기종
Принадлежит: 한국 한의학 연구원, (주)비타바이오

... 본 발명은 치아우식증의 예방 또는 치료용 조성물에 관한 것으로서, 보다 상세하게는 진교 추출물을 유효성분으로 함유하는 치아우식증의 예방 또는 치료용 구강용 조성물 및 건강식품에 관한 것이다. 상기 진교 추출물은 치아우식균에 대한 항균 효과가 우수하고, 치아우식균의 생육 및 균성장시 방출되는 효소인 글루코실트랜스퍼라제의 활성을 억제하며, 그 효과도 지속적일 뿐만 아니라, 천연물인 진교로부터 추출되어 매우 안전하므로, 치아우식증을 예방 및/또는 치료하기 위한 구강용 조성물 또는 건강식품으로 유용하게 사용될 수 있다.

Подробнее
Номер записи: 14
08-10-2015 дата публикации

Compositions for inhibiting metastasis or preventing cancer comprising Illicium verum Hook.f. extract or fraction thereof

Номер: KR0101558946B1
Автор: 마진열, 김애영, 임남희, 임민주, 김태수, 조원경, 정영필
Принадлежит: 한국 한의학 연구원

... 본 발명은 팔각회향 추출물 또는 이의 분획물을 유효 성분으로 포함하는, 암 전이 억제 또는 암 예방용 약학 조성물, 및 식품 조성물에 관한 것이다. 본 발명의 팔각회향 추출물 또는 이의 분획물을 포함하는 조성물은 세포 독성이 낮고 부작용이 거의 없는 장점을 보유하면서도 암 전이를 억제할 수 있으므로, 암전이 또는 암 전이 관련 질환의 치료제, 또는 암 전이 또는 암 전이 관련 질환을 예방 또는 개선할 수 있는 기능성 식품 제제 등으로 유용하게 이용될 수 있다.

Подробнее
Номер записи: 15
18-06-2018 дата публикации

COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY EYE DISEASES COMPRISING EXTRACT OF MAPLE LEAVES OR FRACTION THEREOF

Номер: KR1020180065933A
Автор: MA JIN YEUL, YEOUN HEE KIM, TAE WOO OH, PARK EUN HEE, CHO WON KYUNG, YIM NAM HUI, OH YOU CHANG, GU MINJUNG
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating inflammatory eye diseases comprising an extract of maple leaves or a fraction thereof; a method of treating the diseases comprising a step of administering the composition to the eye of a subject; a quasi-drug composition; an eye cosmetic additive composition; a health functional food composition; and a feed composition. The extract of maple leaves or the fraction thereof are effective for the prevention, alleviation, or treatment of inflammatory eye diseases, in particular dry eye syndrome, conjunctivitis, congestion and keratitis. COPYRIGHT KIPO 2018 ...

Подробнее
Номер записи: 16
24-02-2016 дата публикации

METHOD FOR PREPARING NOODLES

Номер: KR1020160020636A
Автор: LEE, YOON NAM, LIM, NAM HEE
Принадлежит:

The present invention relates to a method for preparing noodles, which comprises the following steps of: mixing and stirring 10-40 parts by weight of wheat flour, 0.0005-0.002 part by weight of sodium hydrogen carbonate, 0.001-0.004 part by weight of a salt, 0.5-2 parts by weight of corn starch, and 4-10 parts by weight of water to make dough; aging the dough wrapped with a hemp cloth-wrapper at 0-5°C using a noodle-making machine to prepare noodles from the aged dough; cooking the noodles in a cooking oil of 120-145°C for 7-10 seconds; and drying and aging the noodles. The noodles prepared by the method of the present invention has excellent mouthfeel and good storage stability at a room temperature or under cold storage conditions to be used as noodles for a Korean dish or a Chinese dish. COPYRIGHT KIPO 2016 ...

Подробнее
Номер записи: 17
16-10-2014 дата публикации

PHARMACEUTICAL COMPOSITION AND FUNCTIONAL HEALTH FOOD FOR PREVENTING OR TREATING CANCER CONTAINING NATURAL EXTRACT AS ACTIVE INGREDIENT

Номер: WO2014168447A1
Автор: MA, Jin Yeul, KIM, Ae Yung, YIM, Nam Hui, IM, Min Ju, KIM, Tae Soo, JUNG, Young Pil
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating cancer containing a mixed medicine extract derived from natural plants as an active ingredient; to a functional health food for preventing or ameliorating cancer; to a method for preventing or treating cancer comprising a step of administering a composition containing a mixed medicine extract derived from natural plants and, more specifically, to a pharmaceutical composition for preventing or treating cancer containing an extract of mixed medicines composed of Cnidium officinale, Ledebouriella seseloides, Korean angelica, Paeonia lactiflora, Forsythia viridissima, Mentha arvensis, Ephedra sinica, Rheum palmatum, gypsum, Platycodon grandiflorum, Scutellaria baicalensis, Atractylodes japonica, Gardenia jasminoides, Schizonepeta tenuifolia, ginger, talc, licorice, Lonicera japonica, Epimedium koreanum, Polygala tenuifolia, and Inula helenium; to a functional health food for preventing or ameliorating cancer ...

Подробнее
Номер записи: 18
31-07-2017 дата публикации

COMPOSITION FOR PREVENTING OR TREATING DRY EYE CONTAINING MAPLE LEAF EXTRACT

Номер: KR101762797B1
Автор: MA, JIN YEUL, OH, YOU CHANG, YIM, NAM HUI, YOO, JAE MYUNG, CHO, WON KYUNG, HWANG, YOUN HWAN, KIM, YEOUN HEE, OH, TAE WOO, PARK, EUN HEE, PARK, KWANG IL
Принадлежит: KOREA INSTITUTE OF ORIENTAL MEDICINE

The present invention relates to a composition for preventing or treating dry eye containing a maple leaf extract. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating dry eye containing a maple leaf extract or a fraction thereof as an active ingredient, a method for preventing or treating dry eye using the pharmaceutical composition, a food composition for preventing or alleviating dry eye containing the maple leaf extract or the fraction thereof as the active ingredient, and a cosmetic composition. The maple leaf extract of the present invention can prevent, ameliorate, and treat dry eye, at a similar or higher level of previously used drugs for treating dry eye. In addition, the composition of the present invention contains natural ingredients, and thus can be safely used for preventing, treating, ameliorating dry eye without side effects. COPYRIGHT KIPO 2017 ...

Подробнее
Номер записи: 19
20-06-2019 дата публикации

COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING INFLAMMATORY DISEASES, CONTAINING, AS ACTIVE INGREDIENT, EXTRACT OF KAKI CALYX OF IMMATURE BANSI (FLAT PERSIMMONS) PRODUCED IN MIRYANG

Номер: WO2019117419A1
Автор: KANG, Young Min, PARK, Jeong Hwan, CHOI, Ji Eun, JOO, Su Ji, SHIM, Ki Shuk, YIM, Nam Hui
Принадлежит:

The present invention relates to a composition for preventing, alleviating or treating inflammatory diseases, containing, as an active ingredient, an extract of Kaki calyx of immature flat persimmons produced in Miryang. An extract, which is an active ingredient of the present invention, of Kaki calyx of immature flat persimmons produced in Miryang has an excellent ability to remove nitric oxide (NO), and thus is effective for anti-inflammation and, when Kaki calyx of immature un-dried persimmons, Kaki calyx of mature un-dried persimmons and Kaki calyx of dried persimmons of respective cultivars (Gojongsi produced in Hamyang, Danseongsi produced in Hamyang and flat persimmons produced in Miryang) are compared, the extract, which is an active ingredient of the present invention, of Kaki calyx of immature flat persimmons produced in Miryang has a relatively superior activity for removing NO, thereby being effectively usable as an anti-inflammatory pharmaceutical composition, a functional ...

Подробнее
Номер записи: 20
12-01-2017 дата публикации

COMPOSITION FOR TREATING CORNEAL DISEASES OR CONJUNCTIVAL DISEASES

Номер: WO2017007273A9
Автор: MA, Jin Yeul, KIM, Jung Hyun, JEON, Jong Wook, OH, You Chang, CHO, Won Kyung, HWANG, Youn Hwan, YIM, Nam Hui, YOO, Jae Myung
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing and treating corneal diseases or conjunctival diseases, containing a maple tree leaf extract as an active ingredient. The maple tree leaf extract exhibits an effect of inhibiting hyperemia in the eyeball of which hyperemia has been induced and of inhibiting angiogenesis in the eyeball of which corneal damage has been induced, thereby being usable in a pharmaceutical composition for preventing and treating corneal diseases or conjunctival diseases.

Подробнее
Номер записи: 21