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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 46. Отображено 46.
31-01-2019 дата публикации

신규 스트렙토코커스 균주를 이용한 강도다리의 세균성 질병 예방용 불활성화 백신

Номер: KR0101944233B1
Принадлежит: 주식회사 코미팜

... 본 발명은 연쇄구균증에 감염된 강도다리로 부터 분리된 알파-용혈성 스트렙토코커스 파라우베리스 HFTC0045 Streptococcus parauberis (미생물 기탁번호KCTC18522P), 알파-용혈성 스트렙토코커스 파라우베리스 HFTC0049 Streptococcus parauberis (미생물 기탁번호KCTC18523P) 균주를 포함하는 연쇄구균증 예방용 혼합 불활성화백신 및 이를 이용하여 어류를 면역시키는 방법에 대한 것이다.

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25-08-2016 дата публикации

황칠나무, 섬오갈피나무 및 인삼이 포함된 복합물의 추출물을 유효성분으로 포함하는 미백 개선용 조성물, 및 이를 이용하여 제조되는 기능성 식품 및 한방 화장품

Номер: KR0101650410B1

... 본 발명은 황칠나무, 섬오갈피나무 및 인삼이 포함된 복합물의 추출물을 유효성분으로 포함하는 미백 개선용 조성물, 및 이를 이용하여 제조되는 기능성 식품 및 한방 화장품에 관한 것으로서, 본 발명의 실시예에 의하면 황칠나무, 섬오갈피나무 및 인삼이 포함된 복합물의 추출물은 멜라닌 합성을 저해, 티로시나아제(tyrosinase) 활성도 저해, tyrosinase 단백질의 발현 감소 및 TRP1, MITF, TRP2 mRNA 발현 감소효과를 통해 미백 개선에 탁월한 효과를 보였다. 따라서 본 발명에 따른 조성물은 미백 개선용 기능성 식품 및 한방 화장품에 유용하게 사용될 수 있다.

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02-10-2018 дата публикации

유연성 반도체 필름 및 그 제조 방법

Номер: KR0101903848B1
Принадлежит: 포항공과대학교 산학협력단

... 본 발명은 유연성 반도체 필름 및 그 제조 방법에 관한 것이다. 본 발명의 일 실시예에 따르면, 본 발명의 일 실시예에 따르면, 유연성 금속 필름, 상기 유연성 금속 필름 상에 배치되며, 이차원 층상 재료를 포함하는 중간층, 및 상기 중간층 상에 배치되며, 에피택시얼 성장으로 이루어진 반도체층을 포함하는, 유연성 반도체 필름을 제공한다.

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29-04-2016 дата публикации

COMPOSITION FOR PREVENTING AND TREATING OBESITY OR HYPERLIPIDEMIA, CONTAINING CURCUMA LONGA AND DENDROPANAX MORBIFERA LEV. AS ACTIVE INGREDIENT

Номер: KR1020160046446A
Принадлежит:

The present invention relates to a composition for preventing and treating obesity and hyperlipidemia, containing Curcuma longa and Dendropanax morbifera LEV. as an active ingredient. More specifically, provided is a composition composed of 30-40% of roots and stems of Curcuma longa, 30-40% of burdock roots, 10-20% of onion, and 5-15% of Dendropanax morbifera LEV. The composition of the present invention exhibits synergistic weight reducing effects in vivo. The composition also exhibits total cholesterol inhibitory effects and also influences on hyperlipidemia. Thus, the composition of the present invention can be useful as a pharmaceutical composition or a functional health food for preventing or treating obesity or arteriosclerotic vascular disease including hypercholesterinemia. COPYRIGHT KIPO 2016 ...

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02-02-2017 дата публикации

COMPOSITION OF MITIGATING, CURING, OR PREVENTING CONSTIPATION BY INCLUDING FERMENTED CASSIA SEEDS AS EFFECTIVE COMPONENT

Номер: KR1020170011391A
Принадлежит:

The present invention relates to health functional food of mitigating, curing, or preventing constipation by including fermented cassia seeds as an effective component, a pharmaceutical composition of curing or preventing constipation, and a manufacturing method of fermented cassia seeds increasing the water content and the weight of excrement. According to the present invention, cassia seeds are used for a long time, have high stability, and include small probability of side-effect occurrence as an herb medicine. The fermented cassia seeds exhibit an effect of increasing the moisture content and weight of excrement equivalent to that of Dulcolax-S, commercialized by using sennoside, or bisacodyl and sodium docusate as an effective component, which are a stimulant constipation banned from being used in health functional food due to a side-effect problem, so as to be used as a pharmaceutical composition for curing or preventing constipation, or health functional food for mitigating or preventing ...

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17-10-2018 дата публикации

COMPOSITION FOR TREATING OR PREVENTING OSTEOPOROSIS, CONTAINING CASSIA SEED EXTRACT

Номер: KR1020180113956A
Принадлежит:

The present invention relates to a composition for preventing and treating osteoporosis, containing a cassia seed extract. The composition containing the cassia seed extract, according to the present invention, has beneficial effects on abnormal skeleton metabolism taking place after ovariosteresis such as suppression of body weight gain, suppression of bone replacement rate, hormone change, recovery of antioxidant renal functions, and suppression of cancellous bone loss, thereby preventing osteoporosis shown in menopausal women clinically. Thus, it is possible to bring beneficial effects on bone metabolism in postmenopausal women. COPYRIGHT KIPO 2018 ...

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13-02-2019 дата публикации

오스문다락톤 및/또는 3,5-디히드록시-감마-카프로락톤을 포함하는 항염증용 조성물

Номер: KR1020190014764A
Принадлежит:

... 본 발명은 오스문다락톤(osmundalactone), 3,5-디히드록시-감마-카프로락톤(3,5-dihydroxy-γ-caprolactone), 또는 이들 화합물의 염을 유효성분으로 포함하는 항염증용 조성물에 관한 것으로, 상기 화합물은 세포 독성이 없고 염증을 예방, 치료 또는 개선하는 효과가 우수하므로 항염증용 의약품, 화장품, 또는 식품에 유용하게 사용할 수 있다.

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04-07-2016 дата публикации

COMPOSITION FOR ALLEVIATING INFLAMMATORY DISEASES, COMPRISING GREEN FERMENTED TEA EXTRACT AS ACTIVE INGREDIENT

Номер: KR1020160077407A
Принадлежит:

The present invention relates to a composition for alleviating inflammatory diseases, comprising a green fermented tea extract as an active ingredient, on the basis of the test results with respect to anti-inflammatory effects of the green fermented tea extract. According to an embodiment of the present invention, a hot water extract of green fermented tea exhibits excellent effects in alleviating inflammatory diseases. According to the present invention, the composition can be efficiently used for the formulation of inflammatory diseases by replacing the conventional substance. COPYRIGHT KIPO 2016 ...

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21-08-2015 дата публикации

Composition for improvement and treatment of inflammatory diseases comprising Alopecurus aequalis Sobol. extract as active componet

Номер: KR0101546021B1
Принадлежит: 조정희

... 본 발명은 뚝새풀 추출물을 유효성분으로 포함하는 것을 특징으로 하는 염증성 질환 개선용 조성물에 관한 것으로서, 본 발명에 따른 뚝새풀 추출물을 이용하여 염증성 질환 관련연구를 진행한 결과, 뚝새풀 추출물(유효농도 100 ~ 200 ㎍/㎖)이 RAW 264.7 세포에서 NF-κB 전사 활성을 억제함으로써 LPS에 의해 유도되는 iNOS 그리고 COX-2 단백질과 pro-inflammatory cytokine인 TNF-α및 IL-6의 발현을 효과적으로 저해하였다. 따라서,뚝새풀 추출물은 대식세포를 매개로한 염증반응의 작용기전 연구에 중요한 기초 자료가 될 수 있을 뿐만 아니라, 향 후 염증성 질환의 예방과 치료에 효과적으로 사용할 수 있을 것으로 기대된다.

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29-10-2015 дата публикации

CONSTIPATION PREVENTION AND ALLEVIATION AGENT USING CASSIA TORA L. AND PREPARATION METHOD THEREFOR

Номер: KR1020150121362A
Принадлежит:

The present invention relates to: a constipation prevention and alleviation agent using Cassia tora L., which prevents and alleviates constipation by a method for inoculating Cassia tora L. powder or Cassia tora L. extract with lactic acid bacteria and fermenting the same; and a preparation method therefor. The method comprises the steps of: (a) supplying Cassia tora L. powder and an antifoaming agent to distilled water so as to make a Cassia tora L. aqueous solution; (b) supplying the Cassia tora L. aqueous solution with a growth medium for lactic acid bacteria; (c) sterilizing the Cassia tora L. aqueous solution supplied with the growth medium for lactic acid bacteria; (d) inoculating the sterilized Cassia tora L. aqueous solution with lactic acid bacteria; (e) fermenting the Cassia tora L. aqueous solution inoculated with lactic acid bacteria; and (f) centrifuging the fermented solution to obtain a supernatant. COPYRIGHT KIPO 2016 ...

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12-01-2018 дата публикации

FLEXIBLE SEMICONDUCTOR FILM AND MANUFACTURING METHOD THEREOF

Номер: KR1020180004583A
Принадлежит:

The present invention relates to a flexible semiconductor film, and a manufacturing method thereof. According to one embodiment of the present invention, the flexible semiconductor film comprises: a flexible metal film; an intermediate layer disposed on the flexible metal film, including a two dimensional layered material; and a semiconductor layer disposed on the intermediate layer, and formed by epitaxial growth, thus capable of strengthening stiffness, intensity of illumination, and weak spots with respect to heat and moisture. COPYRIGHT KIPO 2018 (AA) Semiconductor material (BB) Secondary raw material ...

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04-06-2020 дата публикации

VACCINE COMPOSITION FOR PREVENTING OR TREATING PORCINE EDEMA DISEASE, COMPRISING STX2EA-C-TERMINAL FRAGMENT-STX2EB-PENTAMERIC RECOMBINANT PROTEIN AS ANTIGEN

Номер: WO2020111885A1
Принадлежит:

In the present invention, in order to overexpress a Stx2eA-C-terminal fragment-Stx2eB-pentameric recombinant protein, a Stx2eA-C-terminal fragment gene and a Stx2eB gene, among Stx2e toxins which are one of the causes of porcine edema disease, were cloned into pTWIN1 and pET30a, respectively, and then the vectors were transformed into E.coli BL21(DE3)pLysS. When five Stx2eB monomers expressed from a Stx2eB gene are gathered, monomers form a pentagon structure so as to form a Stx2eB pentamer, and the Stx2eB pentamer and a Stx2eA-C-terminal fragment are coupled so that a stable Stx2eA-C-terminal fragment-Stx2eB-pentameric recombinant protein is produced. A recombinant protein thus produced and an Alum adjuvant were mixed and inoculated, as an antigen of a vaccine for preventing edema disease, in various concentrations into the muscles when piglets were 5 days old and 4 weeks old. After inoculation, in the piglets from groups inoculated with 50 ug and 100 ug of the Stx2eA-C-terminal fragment-Stx2eB-pentameric ...

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03-11-2015 дата публикации

Compositions for Prevention or Treating Autoimmune Thyroid Diseases

Номер: KR0101565029B1

... 본 발명은 연방(nelumbo nucifera Gaerth) 추출물을 유효성분으로 포함하는 자가면역성 갑상선 질환(Autoimmune Thyroid Diseases)의 예방 또는 치료용 약제학적 조성물 또는 자가면역성 갑상선 질환의 완화 또는 개선용 식품조성물에 관한 것이다. 본 발명의 조성물은 히알루로난(Hyaluronan)의 생성, 지방의 분화 및 염증반응을 유의하게 억제함으로써 갑상선 자가항체에 의해 발생하는 다양한 병리적 상태, 예를 들어 갑상선 안구병증을 효과적으로 치료 또는 개선할 수 있다.

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08-03-2018 дата публикации

COMPOSITION FOR PREVENTION OR TREATMENT OF INFLAMMATORY DISEASES COMPRISING SEDUM TAKESIMENSE EXTRACT

Номер: KR1020180024470A
Принадлежит:

The present invention relates to a use of a Sedum takesimense extract having anti-inflammatory activity, and specifically, to a composition for prevention, treatment or alleviation of inflammatory diseases comprising the Sedum takesimense extract as an active ingredient. The Sedum takesimense extract of the present invention inhibits the activation of NF-κB transcription by inhibiting the degradation of IκB-α, and effectively inhibits LPS-induced iNOS and the expression of COX-2 and the proinflammatory cytokines TNF-a and IL-6, IL-lβ at the gene and protein levels to have an excellent anti-inflammatory effect, and thus the composition comprising the Sedum takesimense extract as the active ingredient can be usefully used for inflammation-related diseases. COPYRIGHT KIPO 2018 ...

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08-03-2018 дата публикации

MASTOPARAN PEPTIDE TO PRODUCE KILLED VACCINE, AND KILLED VACCINE USING SAME

Номер: KR1020180024734A
Принадлежит:

The present invention relates to a peptide to produce killed vaccines, and a killed vaccine using the same. More specifically, the present invention relates to a mastoparan peptide to produce killed vaccines, and a method for producing the killed vaccine using the same. According to the present invention, the killed vaccine produced by treating the mastoparan peptide is safe and excellently induces immunity compared to chemical agents such as formalin. COPYRIGHT KIPO 2018 ...

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07-02-2017 дата публикации

ORIENTAL MEDICINAL PAINT COMPOSITION FOR PREVENTING AND AMELIORATING ATOPIC DERMATITIS AND ECO-FRIENDLY ORIENTAL MEDICINAL PAINT USING SAME

Номер: KR1020170013511A
Принадлежит:

The present invention relates to an oriental medicinal paint composition for preventing and ameliorating atopic dermatitis, and to an eco-friendly oriental medicinal paint using the same. According to the present invention, the eco-friendly oriental medicinal paint does not aggravate symptoms of atopic dermatitis, and does not increase in the number of inflammatory cytokine or IgE in blood. Accordingly, the eco-friendly oriental medicinal paint can be useful for alleviating and preventing symptoms of atopic dermatitis. To this end, the oriental medicinal paint composition consists of an eco-friendly resin solution, a first oriental medicinal solution, a second oriental medicinal solution, an eco-friendly acrylic thickener, and distilled water. COPYRIGHT KIPO 2017 ...

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12-12-2017 дата публикации

LACTOBACILLUS CASEI FLORA FOR IMPROVING OR PREVENTING CONSTIPATION BY FERMENTING CASSIA SEEDS

Номер: KR101808306B1

The present invention relates to Lactobacillus casei flora for improving or preventing constipation by fermenting a diluted cassia seed solution and a method of manufacturing a cassia seed Lactobacillus fermentation product by using the same. According to the present invention, Lactobacillus casei K2 flora is effective to improve or prevent constipation only with the diluted cassia seed solution, not a hot cassia seed water extract. Thus, the cassia seed Lactobacillus fermentation product which is prepared using the novel strain to improve or prevent constipation has high stability because of a long use and lowers the generation of side effects from the herb medicine as well as increasing at least one among the volume of excrement, a moisture content of excrement, and weight to the same level as sennoside or Bisacodyl, which is prohibited from being applied to health functional products because of negative side effects, and Dulcolax-S which is now commercialized and contains docusate sodium ...

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28-02-2019 дата публикации

신규 스트렙토코커스 파라우베리스 균주의 방어 혈청형을 포함하는 강도다리 세균성 질병 예방용 불활성화 백신의 제조방법 및 투여방법

Номер: KR0101953460B1
Принадлежит: 주식회사 코미팜

... 본 발명은 연쇄구균증에 감염된 강도다리로부터 분리된 알파-용혈성스트렙토코커스 파라우베리스 HFTC0045 스트렙토코커스 파라우베리스(Streptococcus parauberis) (미생물 기탁번호 KCTC 18522P), HFTC0049 스트렙토코커스 파라우베리스(Streptococcus parauberis) (미생물 기탁번호KCTC18523P), J101 스트렙토코커스 파라우베리스(Streptococcus parauberis) (미생물 기탁번호KCTC18525P), 방어혈청형 균주를 포함하는 연쇄구균증 예방용 혼합 불활성화백신 및 이를 이용하여 어류를 면역시키는 방법에 대한 것이다.

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12-07-2017 дата публикации

VACCINE COMPOSITION FOR PREVENTING OR TREATING PORCINE PROLIFERATIVE ENTERITIS AND SALMONELLOSIS SIMULTANEOUSLY COMPRISING ATTENUATED SALMONELLA MUTANT AS EFFECTIVE COMPONENT

Номер: KR1020170081569A
Принадлежит:

The present invention relates to a vaccine composition for preventing or treating porcine proliferative enteritis and salmonellosis simultaneously comprising an attenuated Salmonella mutant as an effective component. The present invention is a vector developed for increasing the secretion of Lawsonia intracellularis-originated antigens, OptA, OptB, FliC, or Hly, and has transformed an attenuated Salmonella, and in the present invention, it was confirmed that humoral and cell-mediated immune responses to the antigens have been induced in mice administered with a mixture of the transformed attenuated Salmonella mutant. Accordingly, the mutant strain of the present invention can be expected to be beneficially used as a vaccine which is safe, economical, and easy to be administered to a pig for preventing or treating porcine proliferative enteritis and salmonellosis simultaneously. COPYRIGHT KIPO 2017 ...

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21-02-2017 дата публикации

COMPOSITION FOR PREVENTING OR TREATING OBESITY OR HYPERLIPIDEMIA, CONTAINING PEUCEDANI RADIX EXTRACT AS ACTIVE INGREDIENT

Номер: KR1020170019125A
Принадлежит:

The present invention relates to a composition for preventing or treating obesity or hyperlipidemia, containing a Peucedani Radix extract as an active ingredient. The Peucedani Radix extract used as the active ingredient of the present invention suppresses expression of genes associated with fat production and differentiation into adipocytes, and also significantly decreases amounts of adiponectin, leptin, blood lipid, and weight of animal models with obesity and hyperlipidemia, thereby showing efficacy of preventing or treating obesity or hyperlipidemia. Since the Peucedani Radix extract does not cause cytotoxicity, the Peucedani Radix extract is safe to be used in pharmaceutical or food compositions. COPYRIGHT KIPO 2017 ...

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20-05-2015 дата публикации

COMPOSITION FOR IMPROVEMENT OF INFLAMMATORY DISEASES, CONTAINING ALOPECURUS AEQUALIS SOBOL. EXTRACT AS ACTIVE COMPONENT

Номер: KR1020150054038A
Принадлежит:

The present invention relates to a composition for improvement of inflammatory diseases, containing an alopecurus aequalis Sobol. extract as an active component. A result of an inflammatory disease related study using the alopecurus aequalis Sobol. extract shows that by the alopecurus aequalis Sobol. extract (active concentration 100-200 μg/ml) suppressing NF-κB transcription activity in RAW 264.7 cells, transcription of iNOS induced by LPS and COX-2 protein and TNF-α which is a pro-inflammatory cytokine, and IL-6 is effectively inhibited. Therefore, the alopecurus aequalis Sobol. extract can be an important fundamental material for action mechanism studies of inflammatory reaction via macrophage, and effectively used for prevention and treatment of inflammatory diseases in the future. COPYRIGHT KIPO 2015 ...

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06-09-2017 дата публикации

COSMETIC COMPOSITION FOR REDUCING ROSACEA OR IMPROVING WHITENING COMPRISING MEDICINAL HERB EXTRACT

Номер: KR1020170101698A
Принадлежит:

The present invention relates to a cosmetic composition for reducing rosacea or improving whitening, comprising a medicinal herb extract and having excellent functions of reducing rosacea or improving whitening. According to the present invention, by producing a cosmetic product using a medicinal herb extract, it is possible to improve symptoms of skin erythema induced by rosacea. In addition, according to the present invention, by producing a cosmetic product using a medicinal herb extract, it is possible to inhibit the production of melanin and reduce the content of melanin, thereby improving the whitening function. COPYRIGHT KIPO 2017 ...

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01-10-2018 дата публикации

PREPARATION METHOD OF INACTIVATED VACCINE FOR PREVENTION OF STARRY FLOUNDER BACTERIAL DISEASE INCLUDING PROTECTIVE SEROTYPE OF NEW STREPTOCOCCUS PARAUBERIS STRAIN AND ADMINISTRATION METHOD THEREOF

Номер: KR1020180106570A
Принадлежит:

The present invention relates to an alpha-hemolytic Streptococcus parauberis HFTC0045 strain (microorganism deposition number KCTC 18522P), an alpha-hemolytic Streptococcus parauberis HFTC0049 strain (microorganism deposition number KCTC18523P and an alpha-hemolytic Streptococcus parauberis J101 strain (microorganism deposition number KCTC18525P), which are separated from starry flounder infected with streptococcosis, a mixed inactivated vaccine for preventing streptococcosis including a protective serotype strain and a method for immunizing fish by using the same. COPYRIGHT KIPO 2018 (AA) Check a specific band for each S. parauberis serotype ...

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08-03-2018 дата публикации

생약재 추출물을 포함하는 기미개선용 또는 미백용 화장품 조성물

Номер: KR0101835039B1
Принадлежит: 신지현

... 본 발명은 생약재 추출물을 포함하는 기미개선용 화장품 조성물 및 이를 이용한 화장품에 관한 것으로서, 보다 상세하게는 기미개선 및 미백기능이 뛰어난 생약재 추출물을 포함하는 기미개선용 또는 미백용 화장품 조성물에 관한 것이다. 본 발명에 따르면, 생약재 추출물을 이용하여 화장품을 제조함으로써 기미로 인하여 유도된 피부의 색소침착 증상을 완화시킬 수 있는 효과가 있다. 또한 본 발명에 따르면, 생약재 추출물을 이용하여 화장품을 제조함으로써 멜라닌의 생성을 저해하고 멜라닌의 함량을 감소시켜 미백 기능을 향상시킬 수 있는 효과가 있다.

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15-03-2018 дата публикации

COMPOSITION FOR PREVENTING AND TREATING OSTEOPOROSIS INCLUDING CASSIA SEED EXTRACT

Номер: KR1020180027902A
Принадлежит:

The present invention relates to a composition for preventing and treating osteoporosis including a cassia seed extract. The composition including a cassia extract according to the present invention has a beneficial effect against the abnormality of skeletal metabolism occurring after ovariectomy, such as suppression of a weight gain, inhibition of a bone turnover rate, a hormone change, restoration of an antioxidant renal function, and suppression of reduction of cancellous bones, thereby suggesting that osteoporosis in menopausal women can be clinically prevented, and also the present invention is expected to have a beneficial effect on postmenopausal women′s bone metabolism. COPYRIGHT KIPO 2018 ...

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12-01-2018 дата публикации

SELECTIVE REGIONAL GROWTH METHOD OF BORON NITRIDE COMPOUND SEMICONDUCTOR THROUGH METAL SUBSTRATE PATTERNING

Номер: KR1020180004551A
Принадлежит:

According to the present invention, a method injects raw material gas including boron or nitrogen or both boron and nitrogen onto a metal pattern after forming the metal pattern so as to induce a chemical reaction between the boron and the nitrogen on the metal pattern through a catalyst effect of metal, thereby selectively forming a boron nitride compound on the metal pattern. Therefore, the method can be compatible with a microprocessing technology used for microelectronics without using the existing lithography method after growth, and a boron nitride thin film can be obtained without exposure to the remaining organic material. COPYRIGHT KIPO 2018 (A1,A2) Metal thin film (B1,B2,B3) Substrate (CC) Metal thin film deposition (DD) Metal pattern formation (EE) h-BN selective growth ...

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10-06-2016 дата публикации

manufacturing method of preventing and ameliorating constipation thereof

Номер: KR0101628962B1

... 본 발명은 결명자분말 또는 결명자추출물에 유산균을 접종하고 발효시키는 방법으로 변비를 예방하고 개선할 수 있도록 한 결명자를 이용한 변비 예방 및 개선제와 그 제조방법에 관한 것으로, 그 구성은, ⒜ 증류수에 결명자분말, 소포제를 공급하여 결명자수용액을 만드는 단계; ⒝ 상기 결명자수용액에 유산균성장배지를 공급하는 단계; ⒞ 상기 유산균성장배지가 공급된 결명자수용액을 멸균처리하는 단계; ⒟ 상기 멸균처리된 결명자수용액에 유산균을 접종하는 단계; ⒠ 상기 유산균이 접종된 결명자수용액을 발효시키는 단계; ⒡ 상기 발효된 발효액을 원심분리하여 상등액을 수득하는 단계;로 이루어진다 ...

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09-03-2016 дата публикации

COMPOSITION FOR ALLEVIATING, PREVENTING, AND TREATING CONSTIPATION BY USING SENNA TORA FERMENTED WITH LACTIC ACID BACTERIA AS ACTIVE INGREDIENT

Номер: KR101600884B1

The present invention relates to a dietary supplement product for preventing and alleviating constipation by using Senna tora fermented with lactic acid bacteria, a pharmaceutical composition for the same, and a method for preparing the fermented Senna tora in order to increase the weight and moisture content of excrement. The Senna tora fermented with lactic acid bacteria is used for a long time to ensure safety and show little side effects as herbal medicine while showing weight and moisture increasing effects similar to that of Dulcolax-S which uses sennoside, docusate sodium, and bisacodyl as active ingredients and is prohibited from being used as a dietary supplement product due to side effects. Accordingly, the present invention can be used as the pharmaceutical composition for the prevention and treatment of constipation or the dietary supplement product for preventing and alleviating constipation. COPYRIGHT KIPO 2016 (AA) Comparative example 1 (BB) Comparative example 2 (CC) Example ...

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31-03-2017 дата публикации

COMPOSITION FOR ALLEVIATING OR PREVENTING CONSTIPATION CONTAINING DENDROBIUM PLANT EXTRACTS AS EFFECTIVE COMPONENT

Номер: KR1020170035731A
Принадлежит:

The present invention relates to a composition for alleviating or preventing constipation containing Dendrobium plant extracts as an effective component. Since a Dendrobium speciosum extract or a Dendrobium moniliforme extracts, which are used as effective components, exhibit effects of increasing the number and weight of excrement in a constipation animal model, increasing the water content in the excrement to smoothen defecation, and improving intestinal mobility to increase the moving distance of excrement inside intestines while suppressing the changes in fed intakes and weight of the animal model. Therefore, the Dendrobium speciosum extract, Dendrobium moniliforme extract, or a mixture thereof can be helpfully used as compositions for alleviating or preventing constipation. In addition, the Dendrobium speciosum extract or Dendrobium moniliforme extract have no side effects against the human body and are therefore safely used for food or medicines. COPYRIGHT KIPO 2017 ...

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06-09-2017 дата публикации

COSMETIC COMPOSITION FOR WHITENING OR REDUCING FRECKLES CONTAINING MEDICINAL HERB EXTRACT

Номер: KR1020170101694A
Принадлежит:

The present invention relates to a cosmetic composition for reducing freckles containing a medicinal herb extract, and a cosmetic product using the same. More specifically, the present invention relates to a cosmetic composition for whitening or reducing freckles containing a medicinal herb extract excellent in whitening and reducing freckles. According to the present invention, by producing the cosmetic products using the medicinal herb extract, it is possible to alleviate symptoms of pigmentation on skin caused by freckles. In addition, by producing the cosmetic products using the medicinal herb extract, whitening functions can be improved by reducing content of melanin and suppressing melanin production. COPYRIGHT KIPO 2017 ...

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14-12-2015 дата публикации

CITRUS GRANDIS OSBECK EXTRACT HAVING SKIN WHITENING ACTIVITIES AND COSMETIC COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT

Номер: KR1020150139688A
Принадлежит:

The present invention relates to a Citrus grandis Osbeck extract having skin whitening effects, and to a cosmetic composition for skin whitening, containing the extract as an active ingredient. According to the present invention, the Citrus grandis Osbeck extract not only effectively suppresses melanin production by inhibiting activities of tyrosinase which is an essential enzyme involving in a melanin production mechanism, but also shows no cytotoxicity in an application on skin by containing natural ingredients. Furthermore, the composition exhibits excellent skin whitening effects even when adding the composition into a cosmetic base as the active ingredient, thereby being useful as a natural cosmetic composition for skin whitening. COPYRIGHT KIPO 2016 (A1,A2) Citrus tenuissima H_2O (µg,ml) (B1,B2) Citrus tenuissima skin H_2O (µg,ml) ...

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08-08-2017 дата публикации

COMPOSITION FOR PREVENTING OR TREATING NERVE DISORDER CONTAINING LUTEOLIN 5-GLUCOSIDE AS ACTIVE INGREDIENT

Номер: KR101766233B1

The present invention relates to a composition for preventing or treating nerve disorder comprising one or more compounds selected from the group consisting of luteolin 5-glucoside and salts thereof. The compounds selected from the group consisting of luteolin 5-glucoside and salts thereof have no cytotoxicity to nerve cells, and inhibit damage of nerve cells caused by peroxide and formation of reactive oxygen species (ROS) in nerve cells, thereby being safely used in a pharmaceutical or food composition for preventing or treating nerve disorder. COPYRIGHT KIPO 2017 ...

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18-06-2018 дата публикации

INACTIVATED VACCINE FOR PREVENTING BACTERIAL DISEASE IN STARRY FLOUNDER USING NOVEL STREPTOCOCCUS STRAIN

Номер: KR1020180065718A
Принадлежит:

The present invention relates to a mixed inactivated vaccine for preventing streptococcosis, containing an alpha hemolytic Streptococcus parauberis HFTC0049 (microorganism deposit number KCTC18523P) strain and alpha hemolytic Streptococcus parauberis HFTC0045 (microorganism deposit number KCTC18522P) isolated from starry flounder infected with streptococcosis. The present invention further relates to a method for immunizing fish using the same. COPYRIGHT KIPO 2018 (AA) Identify S. parauberis common bands ...

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03-07-2018 дата публикации

METHOD FOR MANUFACTURING NITRIDE SEMICONDUCTOR MATERIAL

Номер: KR101874225B1
Принадлежит: POSTECH ACADEMY-INDUSTRY FOUNDATION

The present invention relates to a method for manufacturing a nitride semiconductor material. The present invention provides the method for manufacturing a nitride semiconductor material, which includes the steps of: arranging a substrate in a chamber; and injecting vapor materials including boron and nitride, respectively, into the chamber and forming hexagonal boron nitride of a two-dimensional layered structure on the substrate by using a chemical reaction according to a process condition set for forming a nitrogen vacancy. Accordingly, the present invention can control the electrical conductivity of the hexagonal boron nitride to improve the degree of freedom in design. COPYRIGHT KIPO 2018 (AA) Start (BB) End (S100) Arranging a substrate in a chamber (S200) Forming hexagonal boron nitride ...

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08-03-2018 дата публикации

PEPTIDE FOR PRODUCTION OF KILLED VACCINE AND KILLED VACCINE USING SAME

Номер: WO2018044018A1
Принадлежит:

The present invention relates to a peptide for the production of an inactivated vaccine and an inactivated vaccine using the same and, more particularly, to a mastoparan peptide for the production of an inactivated vaccine and a method for producing an inactivated vaccine using the same. The inactivated vaccine prepared by treating the mastoparan peptide according to the present invention is safe as compared to an inactivated vaccine prepared by chemical treatment of formalin, etc. and also has an immunity inducing ability equal to or superior to that of a live vaccine.

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08-03-2018 дата публикации

생약재 추출물을 포함하는 주사개선용 또는 미백용 화장품 조성물

Номер: KR0101835040B1
Принадлежит: 신지현

... 본 발명은 주사증 개선 및 미백기능이 뛰어난 생약재 추출물을 포함하는 주사개선용 또는 미백용 화장품 조성물에 관한 것이다. 본 발명에 따르면, 생약재 추출물을 이용하여 화장품을 제조함으로써, 주사증으로 인해 유도된 피부 홍반증상을 개선할 수 있는 효과가 있다. 또한 본 발명에 따르면, 생약재 추출물을 이용하여 화장품을 제조함으로써, 멜라닌의 생성을 저해하고 멜라닌 함량을 감소시켜 미백 기능을 향상시킬 수 있는 효과가 있다.

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22-10-2015 дата публикации

CONSTIPATION PREVENTION AND ALLEVIATION AGENT USING CASSIA TORA L. AND PREPARATION METHOD THEREFOR

Номер: WO2015160043A1
Принадлежит:

The present invention relates to: a constipation prevention and alleviation agent using Cassia tora L., which prevents and alleviates constipation by a method for inoculating Cassia tora L. powder or Cassia tora L. extractwithlactic acid bacteria and fermenting the same; and a preparation method therefor. The method comprises the steps of: (a) supplying Cassia tora L. powder and an antifoaming agent to distilled water so as to make a Cassia tora L. aqueous solution; (b) supplying the Cassia tora L. aqueous solution with a growth medium for lactic acid bacteria; (c) sterilizing the Cassia tora L. aqueous solution supplied with the growth medium for lactic acid bacteria; (d) inoculating the sterilized Cassia tora L. aqueous solution with lactic acid bacteria; (e) fermenting the Cassia tora L. aqueous solution inoculated with lactic acid bacteria; and (f) centrifuging the fermented solution to obtain a supernatant.

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27-01-2016 дата публикации

COMPOSITION COMPRISING WILD DENDROBIUM MONILIFORME EXTRACT AS ACTIVE INGREDIENT FOR SKIN WHITENING AND WRINKLE ALLEVIATION, AND FUNCTIONAL FOOD AND HERBAL COSMETICS MANUFACTURED BY USING SAME

Номер: KR1020160009752A
Принадлежит:

The present invention relates to a composition comprising a wild Dendrobium moniliforme extract as an active ingredient for skin whitening and wrinkle alleviation; and to a functional food and herbal cosmetics manufactured by using the composition. According to an embodiment of the present invention, the wild Dendrobium moniliforme extract shows an excellent effect on improvement in skin whitening due to an inhibitory effect of melanin synthesis, an inhibitory effect of tyrosinase activity, a reducing effect of tyrosinase protein expression, and a reducing effect of mRNA expression of TRP1, MITF, and TRP2. In addition, the wild Dendrobium moniliforme extract according to the present invention increases the biosynthesis rate of type 1 procollagen in fibroblasts derived from the human body, and has inhibited mRNA expression of MMP-1 and MMP-3 caused by TNF-a. Therefore, the composition according to the present invention can be practically used to manufacture a functional food and herbal cosmetics ...

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11-10-2018 дата публикации

COMPOSITION FOR PREVENTING, AMELIORATING AND TREATING MALE MENOPAUSAL SYNDROME COMPRISING COMPLEX EXTRACT OF CORNUS OFFICINALIS, PUERARIA LOBATA ROOT AND LESPEDEZA CUNEATA AS ACTIVE INGREDIENT

Номер: KR1020180111317A
Принадлежит:

The present invention relates to a use of a complex extract of Cornus officinalis, Pueraria lobate, and Lespedeza cuneate having anti-inflammatory activity. Specifically, the present invention relates to a composition for preventing, treating or ameliorating male menopausal syndrome, which comprises a complex extract of Cornus officinalis, Pueraria lobate, and Lespedeza cuneate as an active ingredient. The complex extract of Cornus officinalis, Pueraria lobate, and Lespedeza cuneate of the present invention enhances the NO concentration and vascular relaxation factor, cGMP, which are involved in relaxation and expansion of blood vessels, and exerts an excellent male menopausal syndrome relaxation effect through a mechanism of increasing the secretion amount of testosterone male hormone. Therefore, the composition of the present invention, which comprises a complex extract of Cornus officinalis, Pueraria lobate, and Lespedeza cuneate as an active ingredient, can be usefully used in a pharmaceutical ...

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26-06-2015 дата публикации

Cosmetic composition comprising YeonWooJuanbang and Yeonbang for skin whitening

Номер: KR0101529227B1
Принадлежит: 대한민국(보건복지부장관)

... 본 발명은 연우주안방 및 연방의 추출물을 함유하는 미백 개선용 화장품 조성물, 및 이를 이용하여 제조되는 미백 개선용 화장품으로서, 연화, 연근 및 연자로 구성된 연우주안방과 연방의 물 또는 에탄올 추출물은, 연우주안방과 연방을 건조한 다음, 건조 중량의 10배의 정제수를 포함한 물로 80 내지 100℃의 추출 온도에서 3시간 동안 3회 반복하여 열수 추출, 또는 에탄올 용매로 60 내지 80℃의 추출 온도에서 3시간 동안 3회 반복하여 환류냉각 추출하여 추출물을 수득한 후, 감압여과하고 동결 건조하여 최종 추출물을 수득하는 것을 특징으로 한다. 본 발명에 따른 미백 개선용 화장품은 피부흑화를 개선하고 피부탄력손실 및 피부노화를 방지하는 효과가 있다.

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07-06-2017 дата публикации

COMPOSITION FOR SKIN WHITENING COMPRISING EXTRACT OF CASTANOPSIS SIEBOLDII OR CINNAMOMUM JAPONICUM AS ACTIVE INGREDIENT

Номер: KR1020170061802A
Принадлежит:

The present invention relates to a composition for skin whitening comprising an extract of Castanopsis sieboldii or Cinnamomum japonicum as an active ingredient. The extract of Castanopsis sieboldii or Cinnamomum japonicum can inhibit activity of tyrosinase, inhibit production of melanin, and inhibit the expression of melanin synthesis-related factors, thereby being usefully used as the composition for skin whitening. In addition, the extract of Castanopsis sieboldii or Cinnamomum japonicum has little toxicity to cells, so as to be safely applied to a cosmetic composition for skin whitening. COPYRIGHT KIPO 2017 (AA) CCL: Extract of Castanopsis sieboldii leaf (BB) CCB: Extract of Castanopsis sieboldii branch (CC) CJL: Extract of Cinnamomum japonicum leaf (DD) CJB: Extract of Cinnamomum japonicum branch ...

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05-07-2018 дата публикации

VACCINE COMPOSITION CONTAINING ATTENUATED SALMONELLA MUTANT AS ACTIVE INGREDIENT FOR SIMULTANEOUSLY PREVENTING OR TREATING PORCINE PROLIFERATIVE ENTEROPATHY AND SALMONELLA

Номер: WO2018124407A1
Принадлежит:

The present invention relates to a vaccine composition containing an attenuated Salmonella mutant as an active ingredient for simultaneously preventing or treating porcine proliferative enteropathy and Salmonella. The present invention was confirmed to induce humoral and cell-mediated immune responses to antigens in a mouse vaccinated with a mixture of the attenuated Salmonella mutant, when the attenuated salmonella was transformed using a vector developed to increase secretion of Lawsonia intracellularis-derived OptA, Optb, FliC or Hly antigens. Therefore, the mutant according to the present invention is expected to be useful as a vaccine for simultaneously preventing or treating porcine proliferative enteropathy and Salmonella, which is safe, economical, and safely inoculated.

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13-07-2015 дата публикации

COMPOSITION CONTAINING CHUNGTAEJEON EXTRACT AS ACTIVE INGREDIENT FOR HAVING ANTI-OBESITY EFFECT AND REDUCING BODY FAT

Номер: KR1020150080970A
Принадлежит:

The present invention relates to a composition for reducing a body fat wherein the composition contains a chungtaejeon extract as an active ingredient based on a verification result on the anti-obesity effect of the chungtaejeon extract. Chungtaejeon literally means a blue moss and is a type of a green tea. According to one embodiment of the present invention, the chungtaejoen extract has excellent anti-obesity and weight loss effects and shows an excellent effect of suppressing obesity. Accordingly, the composition of the present invention can be usefully used as an obesity treatment agent by replacing a conventional material. COPYRIGHT KIPO 2015 ...

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29-10-2018 дата публикации

MANUFACTURING METHOD OF ORAL PREPARATION COATED WITH CALCIUM CHLORIDE AND LEVAN

Номер: KR101912525B1
Принадлежит: JUNWON GBI CO., LTD.

The present invention relates to a manufacturing method of an oral preparation coated with calcium chloride and levan. The oral preparation coats a target material supported on an alginic acid with calcium chloride and levan. According to the present invention, probiotics such as lactobacillus in which activity is easily inhibited due to various drugs and stomach acids, which are prevented from being absorbed in a gastrointestinal, are emitted in a small intestine, thereby manufacturing the oral preparation having excellent selective drug transmissibility. The manufacturing method comprises: a first step of preparing an alginic acid solution, a calcium chloride solution and a levan solution on which the target material is supported; a second step of mixing the calcium chloride solution and the levan solution to manufacture a coating solution, and dropping the alginic acid solution on which the target material is supported to the coating solution; and a third step of collecting and drying ...

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15-09-2015 дата публикации

COMPOSITION CONTAINING ALLIUM HOOKERI EXTRACT AS ACTIVE INGREDIENT FOR IMPROVING LIVER FUNCTION OR PROTECTING LIVER DAMAGE

Номер: KR101552970B1

The present invention relates to a composition for preventing, alleviating or treating liver disease, and a health functional food for alleviating liver damage, containing an Allium hookeri extract as an active ingredient. When applied to animal models with liver toxicity, the Allium hookeri extract according to the present invention significantly decreases aspartate aminotransferase (ALT) and alanine aminotransferase (AST) values, which are widely known as liver damage indicators, and increases the expression of an anti-oxidizing enzyme such as catalase and glutathione peroxidase, thereby effectively protecting the liver form oxidative stress caused by liver damage. Therefore, the composition containing the extract as an active ingredient, according to the present invention, can be usefully used in preventing, alleviating or treating liver damage. Particularly, the Allium hookeri extract is an edible medicinal plant, so the composition containing the extract as an active ingredient can ...

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11-12-2015 дата публикации

SKIN-WHITENING COMPOSITION INCLUDING COMPOSITE EXTRACT OF PANAX GINSENG, DENDROPANAX MORBIFERA LEVEILLE, AND ACANTHOPANAX KOREANUM NAKAI AS ACTIVE INGREDIENT, FUNCTIONAL FOOD COMPOSITION PREPARED BY USING SAME, AND ORIENTAL COSMETIC PRODUCT THEREOF

Номер: KR1020150138875A
Принадлежит:

The present invention relates to a skin-whitening composition including a composite extract including Dendropanax morbifera Leveille, Acanthopanax koreanum Nakai, and Panax ginseng as an active ingredient, a functional food product prepared by using the same, and an oriental cosmetic product thereof. The composite extract exhibits an excellent skin-whitening effect by inhibiting the activity of tyrosinase and melanin synthesis and reducing the expression of the tyrosinase proteins and the expression of TRP1, MITF, and TRP2 mRNA. Accordingly, the composition can be used in the skin-whitening functional food product and the oriental cosmetic product. COPYRIGHT KIPO 2016 ...

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