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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 87. Отображено 87.
15-01-2016 дата публикации

Apparatus for Treating Bulk Ore from Conveyer

Номер: KR0101585677B1
Автор: 황재관, 육심주, 윤영희, 김영수
Принадлежит: 주식회사 포스코

... 컨베이어에 적재되는 괴광과 같은 비정상(크기의) 적재물을 처리 가능하게 한 컨베이어의 비정상 적재물 처리장치가 제공된다. 상기 컨베이어의 비정상 적재물 처리장치는, 비정상 적재물을 포함하는 적재물을 운송하는 이송 컨베이어에 연계 배치된 슈트; 상기 슈트의 일측에 배치되면서 이송 컨베이어로부터 불출되는 비정상 적재물을 감지토록 제공된 감지유닛; 상기 감지유닛의 일측으로 슈트에 배치되면서 감지된 비정상 적재물을 선별토록 제공된 선별유닛; 및, 상기 선별유닛의 일측으로 슈트에 배치되면서 선별된 비정상 적재물을 정상 적재물의 크기로 파쇄하는 괴광 파쇄유닛;을 포함하고, 상기 비정상 적재물은 괴광으로 이루어 지고, 상기 정상 적재물은 소결광으로 이루어지며, 상기 슈트는, 상기 이송 컨베이어의 출측으로 높이차를 갖고 배치되되, 상기 괴광 감지유닛, 괴광 선별유닛과, 괴광 파쇄유닛을 구분 배치하도록 한 격벽이 상기 괴광파쇄유닛 측으로 제공되고, 상기 선별유닛은, 상기 슈트에 구비된 프레임에 간격이 조정된 상태로 설치되어 정상 적재물인 소결광은 상기 선별유닛 하측으로 통과시키고 비정상 적재물인 괴광만을 선별 이동토록 제공된 회동아암; 및, 상기 회동아암 사이에 배치되고, 상기 회동아암에 의해 선별된 비정상 적재물인 괴광을 상기 괴광 파쇄유닛측으로 안내하는 가이드바;를 포함하여 구성된 컨베이어의 비정상 적재물 처리장치를 제공한다. 이와 같은 본 발명에 의하면, 괴광과 같은 비정상(크기의) 적재물이 이송 컨베이어에 적재되면 그 불출단계에서 감지, 선별 또는 파쇄의 일련의 작동을 구현하여 괴광 처리를 효과적으로 수행 가능하게 하고, 이에 따라 괴광에 의한 슈트 막힘이나 적재물 운송 중단 등을 방지하고, 이를 처리하기 위한 추가적인 조업이나 작업자의 안전사고 등도 예방 가능하게 하는 개선된 효과를 얻을 수 있다.

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Номер записи: 1
09-11-2017 дата публикации

COMPOSITION FOR IMPROVING MUSCULAR FUNCTION OR FOR ENHANCING EXERCISE PERFORMANCE COMPRISING VIGNA ANGULARIS VAR. ANGULARIS

Номер: WO2017192013A1
Автор: HWANG, Jae Kwan, LEE, Se In, KIM, Mi Bo, KIM, Chang Hee
Принадлежит:

Vigna angularis var. angularis according to the present invention is capable of increasing muscle mass and enhancing muscular function or exercise performance through an effect of promoting mRNA or protein expression and the activity of a gene involved in muscle functions, muscle mass increase or differentiation of muscle cells; can prevent, treat or ameliorate a decline in exercise performance, a decline in muscle function, muscle loss, etc. caused by various diseases; and may be effectively used for medicines or food products, etc., since it has no side effects in the body as a natural substance.

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Номер записи: 2
06-12-2016 дата публикации

COMPOSITION FOR PREVENTING AND TREATING MUSCLE DISEASE OR IMPROVING MUSCULAR FUNCTIONS, CONTAINING BALLOON-FLOWER EXTRACT

Номер: KR1020160138927A
Автор: HWANG, JAE KWAN, KIM, MI BO, KIM, CHANG HEE, KIM, DO UN, CHUNG, HEE CHUL
Принадлежит:

The present invention relates to a composition for preventing and treating muscle disease or improving muscular functions, containing a balloon-flower extract. More specifically, the present invention relates to a pharmaceutical composition for preventing and treating muscle disease containing a balloon-flower extract, a food composition for preventing muscle disease or improving muscular functions, or a cosmetic ingredient for improving muscular functions. The balloon-flower extract can promote muscle formation by inducing differentiation of muscle cells as well as myoprotein synthesis, and is derived from natural substances, thereby being safe without side effects. In addition, the balloon-flower extract can be used as an effective component in pharmaceutical, food, or cosmetic compositions showing excellent efficacy on preventing and treating muscle disease or improving muscular functions. COPYRIGHT KIPO 2016 (AA) Balloon-flower extract (10 μg/ml) ...

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Номер записи: 3
24-12-2015 дата публикации

COMPOSITION FOR REDUCING BODY FAT COMPRISING XANTHORRHIZOL OR JAVA TUMERIC EXTRACT AS ACTIVE INGREDIENT

Номер: KR1020150144160A
Автор: HWANG, JAE KWAN, KIM, MI BO
Принадлежит:

The present invention relates to a composition for reducing body fat of xanthorrhizol or a Java turmeric extract comprising the same. The xanthorrhizol or the Java turmeric extract comprising the same of the present invention shows an excellent body fat reducing effect by reducing weight of visceral adipose tissues and adipocyte size in an obesity animal model. Therefore, the composition shows an outstanding effect in decreasing the body fat and can be safely without side effects since the composition is based on natural substances. COPYRIGHT KIPO 2016 (AA,DD) High fat diet(Control group) (BB,EE) High fat diet + Xanthorrhizol (CC) Size of fat cell(Control group %) ...

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Номер записи: 4
27-02-2020 дата публикации

COMPOSITION FOR PREVENTING OR TREATING MUSCULAR DISEASES, OR FOR IMPROVING MUSCULAR FUNCTIONS, CONTAINING GAGNLIOSIDE

Номер: WO2020040615A1
Автор: HWANG, Jae Kwan, SU, Seung Tae, KIM, Jong Wook, KIM, Chang Hee, YOO, Ji Hee
Принадлежит:

The present invention relates to a composition for preventing or treating muscular diseases, or for improving muscular functions, containing gagnlioside. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating muscular diseases, a food composition for preventing or alleviating muscular diseases, or a cosmetic composition for preventing or alleviating muscular diseases, all of which comprise gagnlioside, which can increase the expression of proteins associated with muscle protein synthesis and muscle mass growth in muscle cells and inhibit the expression of enzymes involved in muscle protein degradation at the mRNA level.

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Номер записи: 5
10-08-2017 дата публикации

메이스리그난 또는 육두구 추출물을 유효성분으로 하는 가려움증 완화 또는 피부손상 개선용 조성물

Номер: KR0101767261B1
Автор: 김도언, 황재관
Принадлежит: (주)뉴트리, (주)앗코스텍

... 본 발명은 메이스리그난 또는 육두구 추출물의 새로운 용도에 관한 것으로, 보다 상세하게는 메이스리그난 또는 이의 염 또는 육두구 추출물을 유효성분으로 포함하는 가려움증 완화 또는 피부손상 개선용 식품 조성물, 화장료 조성물 및 가려움증 또는 피부손상 치료용 약학적 조성물에 관한 것이다. 본 발명의 조성물은 비만세포의 탈과립이나 히스타민의 분비를 현저하게 저해함으로써 가려움증을 완화하는 데에 효과적이며, 피부 손상 부위에 작용하여 정상 표피로 회복시키도록 하므로 매우 유용한 피부 손상 또는 가려움증 예방/치료/개선/경감용 조성물을 제공한다.

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Номер записи: 6
03-08-2015 дата публикации

COMPOSITION CONTAINING FUCOSTEROL FOR SKIN WHITENING OR MOISTURIZING

Номер: KR1020150088750A
Автор: HWANG, JAE KWAN, KIM, CHANG HEE, KIM, MI BO, WOO, SEON WOOK
Принадлежит:

The present invention relates to a novel use of fucosterol and, more particularly, to a composition for skin whitening or moisturizing, which is characterized by containing fucosterol. Fucosterol of chemical formula 1 has an excellent whitening effect of inhibiting melanin generation and tyrosinase activity, and thus can be used as an active ingredient of a cosmetic composition for whitening, a food composition or a pharmaceutical composition. In addition, the fucosterol of chemical formula 1 has an excellent moisturizing function by forming dead skin cell membranes, promoting the differentiation of dead skin cells, and generating natural moisturization factors. Therefore, the fucosterol can be used as an active ingredient of a cosmetic composition for moisturizing, a food composition or a pharmaceutical composition. COPYRIGHT KIPO 2015 (AA) Melanin content compared with control group (%) (BB) Sample (CC) Fucosterol ...

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Номер записи: 7
24-05-2018 дата публикации

METHOD FOR PREPARING CURCUMA XANTHORRHIZA ROXB. EXTRACT

Номер: WO2018093077A1
Автор: KWON, Jin Hyouk, YOON, Mann-Seok, LEE, Jin Woo, SHIM, Jae Seok, PARK, Young Min, KIM, Jin Hak, SUNG, Na Hye, HWANG, Jae Kwan, PARK, Jin Woo, CHOI, Su Young
Принадлежит:

The present invention relates to a method for preparing a Curcuma xanthorrhiza Roxb. extract. The present invention provides a method for preparing a Curcuma xanthorrhiza Roxb. extract comprising: a step of extracting Curcuma xanthorrhiza Roxb. by supercritical extraction to thereby obtain an extract comprising xanthorrhizol as an active ingredient; a step of extracting the residue of the supercritical extraction by alcohol extraction or supercritical extraction to thereby obtain an extract comprising curcumin as an active ingredient; a step of subjecting the residue of the alcohol extraction or supercritical extraction to an enzyme treatment to thereby obtain immunopolysaccharides having an average molecular weight of 33,000 Da; and a step of obtaining an insoluble dietary fiber in the residue of the enzyme treatment, and provides an extract comprising xanthorrhizol, curcumin, immunopolysaccharides, and insoluble dietary fibers obtained by the method described above, and general food, ...

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Номер записи: 8
20-07-2017 дата публикации

키레놀 또는 희첨 추출물을 포함하는 근 기능 개선용 조성물

Номер: KR0101759779B1
Автор: 황재관, 김미보, 김창희
Принадлежит: 연세대학교 산학협력단

... 본 발명은 키레놀(kirenol), 이를 함유하는 희첨(Hui Chum, Siegesbeckia spp.) 추출물 또는 이의 분획물을 유효성분으로 포함하는 근기능 개선용 조성물에 관한 것이다. 본 발명에 따른 키레놀(kirenol), 또는 이를 함유하는 희첨 추출물 또는 이의 분획물은 근기능에 관여하는 주요 유전자 p-mTOR의 단백질 발현을 증가시킴에 따라, 근기능을 탁월하게 증강하는 효과가 있다. 또한, 본 발명은 천연물이므로 부작용 없이 안전하게 사용될 수 있어, 의약품 또는 식품으로 사용될 수 있다.

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Номер записи: 9
09-08-2017 дата публикации

COMPOSITION FOR INCREASING EXERCISE CAPACITY COMPRISING EXTRACT OF SIEGESBECKIA SPP.

Номер: KR1020170091564A
Автор: HWANG, JAE KWAN, KIM, MI BO, KIM, CHANG HEE
Принадлежит:

The present invention relates to a composition for increasing exercise capacity, especially endurance comprising kirenol or an extract of Hui Chum (Siegesbeckia spp.) containing the same as an active ingredient. The kirenol, the extract of Siegesbeckia spp. or fractions thereof increase protein expression of main genes associated with improvement in endurance to significantly increase exercise capacity, and can be safely used without side effects as natural materials to be used as medicines or foods. COPYRIGHT KIPO 2017 (AA) Control group (BB) Siegesbeckia glabrescens 10 ppm (CC) Siegesbeckia pubescens 10 ppm (DD) Siegesbeckia orientalis 10 ppm (EE) Kirenol 10 μM ...

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Номер записи: 10
31-05-2017 дата публикации

COMPOSITION COMPRISING MORUSIN, KUWANON G, OR MORI CORTEX RADICIS, FOR PREVENTING AND TREATING MUSCULAR DISEASES OR IMPROVING MUSCULAR FUNCTIONS

Номер: KR1020170059941A
Автор: HWANG, JAE KWAN, KIM, MI BO, KIM, CHANG HEE, KIM, DO UN, CHUNG, HEE CHUL
Принадлежит:

The present invention relates to a composition for preventing and treating muscular diseases or improving muscular functions, comprising at least one selected from the group consisting of morusin, kuwanon G, and an extract of Mori Cortex Radicis as an active ingredient. The extract of Mori Cortex Radicis, morusin, or kuwanon G according to the present invention has an excellent effect of enhancing muscular functions by increasing the expression of p-mTOR protein involved in muscle protein synthesis, inhibiting the expression of mRNAs of MuRF-1 and atrogin-1 involved in muscle protein breakdown, and increasing the expression of mRNAs of MyoD and myogenin involved in muscle differentiation. Also, the present invention is a natural product that can be used safely without side effects, and thus can be used as a drug, food product, or cosmetic product. COPYRIGHT KIPO 2017 (AA) Control group (BB) Morucin 5μM (CC) Kuwanon G 5μM (DD) Hot-water extract of Mori Cortex Radicis 20μg/ml (EE) Ethanol ...

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Номер записи: 11
05-10-2018 дата публикации

퓨코스테롤을 유효성분으로 포함하는 피부주름 개선 또는 피부탄력 증진용 화장료 조성물

Номер: KR0101904501B1
Автор: 황재관, 김명석, 오가희
Принадлежит: (주)앗코스텍

... 본 발명은 퓨코스테롤의 새로운 용도에 관한 것으로, 더욱 상세하게는 퓨코스테롤을 유효성분으로 포함하는 피부주름 또는 피부노화 개선용 화장료 조성물에 관한 것이다. 본 발명의 조성물은 콜라겐 분해효소를 억제하고, 콜라겐의 생성을 촉진하는 효능이 뛰어나 피부의 주름 개선, 피부노화 및 피부 탄력 증진에 효과적이고, 이를 이용한 건강기능식품 조성물 및 치료용 약학적 조성물에 관한 것이다.

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Номер записи: 12
10-08-2017 дата публикации

길경 추출물을 함유하는 근육 질환 예방 및 치료용 또는 근 기능 개선용 조성물

Номер: KR0101767244B1
Автор: 황재관, 김미보, 김창희, 김도언, 정희철
Принадлежит: (주)뉴트리

... 본 발명은 길경 추출물을 함유하는 근육 질환 예방 및 치료용 또는 근 기능 개선용 조성물에 관한 것으로, 보다 상세하게는 길경 추출물을 포함하는 근육 질환 예방 및 치료용 약학 조성물, 근육 질환 예방용 또는 근 기능 개선용 식품 조성물 또는 근 기능 개선용 화장료에 관한 것이다. 본 발명의 길경 추출물은 근 단백질 합성 및 근육세포의 분화를 일으켜 근육 형성을 증가시킨다. 따라서 천연물이므로 부작용 없이 안전하게 사용될 수 있으며, 근육 질환 예방 및 치료 또는 근 기능 개선에 탁월한 효과를 보이는 약학적, 식품 또는 화장료 조성물의 유효한 성분으로 이용될 수 있다.

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Номер записи: 13
13-03-2018 дата публикации

자바강황 추출물 또는 잔소리졸을 유효성분으로 함유하는 타액 분비 증강용, 또는 구강건조증 예방, 개선 또는 치료용 조성물

Номер: KR0101838379B1
Автор: 황재관, 이선규
Принадлежит: 연세대학교 산학협력단

... 본 발명의 잔소리졸 또는 자바강황(Curcumaxanthorrhiza) 추출물을 유효성분으로 포함하는 조성물에 관한 것으로, 상기 조성물은 침샘세포에서 타액분비와 관련된 유전자 및 단백질의 활성을 촉진하고, 세포 내 Ca2+의 농도를 증가시켜 액체의 전해질 분비를 증가시켜 타액분비증강을 통한 구강건조 또는 타액분비이상을 예방, 치료 또는 개선할 수 있고, 천연물로서 부작용 없이 안전하게 사용될 수 있어 의약품, 의약외품 또는 식품 등의 제조에 효과적으로 사용될 수 있다.

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Номер записи: 14
10-11-2017 дата публикации

COMPOSITION FOR IMPROVING MOTOR ABILITY OR MYOFUNCTION CONTAINING ADZUKI BEANS

Номер: KR1020170124473A
Автор: HWANG, JAE KWAN, LEE, SE IN, KIM, MI BO, KIM, CHANG HEE
Принадлежит:

According to the present invention, adzuki beans can promote activities and expression of protein or mRNA of a gene involved in differentiation of muscular cells or increasing muscle mass and muscular functions, thereby increasing muscle mass and improving motor ability or myofunction. In addition, adzuki beans are able to prevent, treat, or ameliorate a loss of muscles as well as reduction in motor ability due to various diseases, and thus can be effectively used for foods or drugs as a natural substance without causing side effects in body. COPYRIGHT KIPO 2017 (AA) Relative mTOR activity (% of control) (BB) Sample (μ g / mL) (CC) Red bean ethanol extract ...

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Номер записи: 15
12-12-2016 дата публикации

SKIN ANTI-AGING FOOD COMPOSITION COMPRISING β-SITOSTEROL OR BROWN RICE EXTRACT

Номер: KR1020160142030A
Автор: HWANG, JAE KWAN, JEONG, JAE HONG, KIM, CHANG HEE, RHIM, DONG BIN
Принадлежит:

The present invention relates to a novel use of β-sitosterol or a brown rice extract and, more specifically, to a skin anti-aging food composition through PPARα by containing a brown rice extract. The brown rice extract has excellent skin anti-aging activity through interrupting the decomposition of collagen and promoting the synthesis of collagen, thereby being used as an effective component of a skin anti-aging food composition. COPYRIGHT KIPO 2016 (A1,A2,A3,A4) Control group ...

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Номер записи: 16
15-02-2016 дата публикации

COMPOSITION FOR SKIN WHITENING COMPRISING KIRENOL OR SIGESBECKIA PUBESCENS L. EXTRACT

Номер: KR1020160015502A
Автор: HWANG, JAE KWAN, KIM, MI BO, LEE, SUN AH
Принадлежит:

The present invention relates to a new usage of kirenol, a Sigesbeckia pubescens L. extract, or a fraction thereof and, more specifically, to a composition for skin whitening containing kirenol or a Sigesbeckia pubescens L. extract containing the same. The extract can be extracted by one or more solvent selected from a group including water, a C1 to C6 organic solvent, subcritical fluid, and supercritical fluid. According to the present invention, the kirenol or a Sigesbeckia pubescens L. extract containing the same controls melanin generation and tyrosinase activity, thereby having an excellent skin whitening effect. Also, the skin whitening composition in the present invention is a natural material, thereby being safely used without side effects and being used as cosmetics or foods. COPYRIGHT KIPO 2016 (AA) Melanin contents in comparison with a control group (BB) Specimen (CC) Kirenol ...

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Номер записи: 17
02-07-2020 дата публикации

COMPOSITION FOR PREVENTING AND TREATING MUSCLE DISEASE OR IMPROVING MUSCLE FUNCTION, COMPRISING ILLICIUM VERUM EXTRACT OR SHIKIMIC ACID

Номер: WO2020139057A3
Автор: HWANG, Jae Kwan, KIM, Changhee, YOO, Ji Hee
Принадлежит:

The present invention relates to a composition for preventing and treating a muscle disease or improving muscle function, comprising an Illicium verum extract and shikimic acid. The Illicium verum extract and shikimic acid according to the present invention have the effect of increasing activity of mTOR involved in muscle protein synthesis and reducing the mRNA expression of MuRF-1 and atrogin-1 involved in muscle protein degradation, and increase muscle mass and enhance muscle function, thereby being useful for preventing, treating, or alleviating various muscle diseases such as atony, muscular atrophy, muscular dystrophy, muscular degeneration, myasthenia, cachexia, and sarcopenia.

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Номер записи: 18
30-07-2015 дата публикации

COMPOSITION CONTAINING FUCOSTEROL FOR SKIN WHITENING OR MOISTURIZING

Номер: WO2015111953A1
Автор: HWANG, Jae Kwan, WOO, Seon Wook, KIM, Chang Hee, KIM, Mi Bo
Принадлежит:

The present invention relates to a novel use of fucosterol and, more specifically, to a composition for skin whitening or composition for skin moisturizing, which is characterized by containing fucosterol. Fucosterol of chemical formula 1 below has an excellent whitening effect of inhibiting melanin generation and tyrosinase activity, and thus can be used as an active ingredient of a cosmetic composition for whitening, a food composition, or a pharmaceutical composition. Furthermore, the fucosterol of chemical formula 1 below has an excellent moisturizing function by forming dead skin cell membranes, promoting the differentiation of dead skin cells, and generating natural moisturization factors, and thus can be used as an active ingredient of a cosmetic composition for moisturizing, a food composition, or a pharmaceutical composition. [Chemical formula 1] ...

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Номер записи: 19
21-11-2013 дата публикации

USE OF KAEMPFERIA PARVIFLORA WALL. EX. BAKER EXTRACTS OR FLAVONE COMPOUND FOR PREVENTING OR TREATING MUSCLE DISEASES, OR IMPROVING MUSCLE FUNCTION

Номер: WO2013172681A1
Автор: HWANG, Jae-Kwan, SA, Bo Kyung, KIM, Tae Yoon
Принадлежит:

The present invention relates to a pharmaceutical composition containing Kaempferia parviflora Wall. Ex. Baker extracts for treating muscle diseases, and more specifically to a pharmaceutical composition containing, as an active ingredient, Kaempferia parviflora Wall. Ex. Baker extracts or flavone compound isolated therefrom for treating muscle diseases or a dietary composition for improving muscle function. Kaempferia parviflora Wall. Ex. Baker extracts or flavone compound isolated therefrom according to the present invention reduces protein catabolism in the muscles and increases muscle cell differentiation and anbolism, and is thus effective for producing pharmaceutical composition for treating muscle diseases and dietary composition for improving muscle function.

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Номер записи: 20
28-05-2018 дата публикации

METHOD FOR PRODUCING CURCUMA XANTHORRHIZA ROXB. EXTRACT

Номер: KR1020180056209A
Автор: KWON, JIN HYOUK, YOON, MANN SEOK, LEE, JIN WOO, SHIM, JAE SEOK, PARK, YOUNG MIN, KIM, JIN HAK, SUNG, NA HYE, HWANG, JAE KWAN, PARK, JIN WOO, CHOI, SU YOUNG
Принадлежит:

The present invention relates to a method for producing a Curcuma xanthorrhiza Roxb. extract; an extract including xanthorrhizol, curcumine, immunopolysaccharide, and insoluble edible fiber, which is obtained by the method; and a general food, health functional food, cosmetic product, or pharmaceutical composition including the extract as an active ingredient. The method comprises the steps of: obtaining an extract having xanthorrhizol as an active ingredient by performing supercritical extraction on Curcuma xanthorrhiza Roxb.; obtaining an extract having curcumine as an active ingredient by performing liquor extraction or supercritical extraction on the supercritical extraction residue; obtaining immunopolysaccharide having an average molecular weight of 33,000 Da by enzymatically treating the liquor extraction or supercritical extraction residue; and obtaining insoluble edible fiber from the enzymatically treated residue. The method according to the present invention gradually applies ...

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Номер записи: 21
08-02-2018 дата публикации

COMPOSITION CONTAINING SQUALENE FOR IMPROVING MUSCLE FUNCTION AND PREVENTING MUSCLE DAMAGE

Номер: WO2018026211A1
Автор: HWANG, Jae Kwan, LEE, Se In, KIM, Mi Bo, KIM, Chang hee
Принадлежит:

The present invention relates to a composition for preventing, treating, improving a muscle disease or regenerating muscle damage, containing squalene. More specifically, the squalene of the present invention increases the expression of proteins involved in muscle protein synthesis and muscle mass increase in muscle cells, inhibits an expression of enzymes involved in myoprotein degradation at the level of mRNA, and has an effect of restoring the recovery of damaged muscle quickly. Also, the present invention is a natural product so as to be safely used without side effects, and thus can be used as medicine, food, or cosmetics.

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Номер записи: 22
30-04-2020 дата публикации

COMPOSITION FOR ALLEVIATION OF SKIN IRRITATION INDUCED BY ENVIRONMENTAL POLLUTION FACTORS OR FOR SKIN PROTECTION, CONTAINING NUTMEG EXTRACT OR MACELIGNAN AS ACTIVE INGREDIENT

Номер: WO2020085826A1
Автор: HWANG, Jae Kwan, PARK, Jihye, KANG, Haneul, KIM, Chang Hee, CHUNG, Hee Chul, KIM, Do Un
Принадлежит:

The present invention relates to a composition for the alleviation of skin irritation induced by environmental pollution factors or for skin protection, containing a nutmeg extract or macelignan as an active ingredient. A nutmeg extract and macelignan of the present invention have reduced the expression of gene CYP1A1 mediated by XRE, and have alleviated skin damaged by fine dust, thereby having excellent effects in the alleviation of skin irritation induced by environmental pollution factors and in skin protection. In addition, the composition of the present invention is a natural material, and thus can be safely used without side effects, thereby being usable as food and a cosmetic composition.

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Номер записи: 23
08-09-2017 дата публикации

COMPOSITION COMPRISING PANDURATIN OR FINGERROOT (BOESENBERGIA PANDURATA) EXTRACT FOR TREATING, PREVENTING, OR AMELIORATING BONE LOSS DISEASE

Номер: WO2017150934A1
Автор: HWANG, Jae Kwan, KIM, Si Yeon, KIM, Mi Bo
Принадлежит:

The present invention relates to a composition comprising a panduratin derivative or a boesenbergia pandurata extract as an effective ingredient, which suppresses the differentiation of osteoclasts to exhibit the effect of treating, preventing or ameliorating bone loss diseases and which can be used safely as a natural material without side effects, thus finding effective applications in drugs, quasi-drugs, or foods.

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Номер записи: 24
15-06-2015 дата публикации

Composition for prevention and treatment of muscular disorder or improvement of muscular functions comprising Kaempferia parviflora extract or flavone compounds

Номер: KR0101528023B1
Автор: 황재관, 사보경, 김태윤
Принадлежит: 연세대학교 산학협력단

... 본 발명은 캠페리아 파비플로라(Kaempferia parviflora Wall. ex Baker) 추출물 또는 플라본계 화합물을 함유하는 근육 질환 치료용 약학적 조성물에 관한 것으로, 보다 상세하게는 캠페리아 파비플로라 추출물 또는 이로부터 분리된 화학식 4로 표시되는 플라본계 화합물을 유효성분으로 포함하는 근육 질환 치료용 약학적 조성물, 근 기능 개선용 식품 조성물 및 운동수행능력 증강용 식품 조성물에 관한 것이다. 본 발명은 캠페리아 파비플로라 추출물과 이로부터 분리된 플라본계 화합물은 근육 내 단백질의 이화 작용을 감소시키고 근육 세포 분화 및 동화 작용을 증가시키므로, 근육 질환 치료용 약학적 조성물 또는 근 기능 개선용 식품 조성물을 제조하는데 효과적이다.

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Номер записи: 25
10-03-2017 дата публикации

퓨코스테롤을 함유하는 피부 미백 또는 보습용 조성물

Номер: KR0101714434B1
Автор: 황재관, 김창희, 김미보, 우선욱
Принадлежит: 연세대학교 산학협력단

... 본 발명은 퓨코스테롤(fucosterol)의 신규한 용도에 관한 것으로, 보다 상세하게는 퓨코스테롤을 함유하는 것을 특징으로 하는 피부 미백 또는 보습용 조성물에 관한 것이다. 하기 화학식 1의 퓨코스테롤은 멜라닌 생성 및 티로시나제 활성을 억제하는 탁월한 미백 효과가 있으므로 미백용 화장료 조성물, 식품 조성물 또는 약학적 조성물의 유효한 성분으로 이용될 수 있다. 또한, 하기 화학식 1의 퓨코스테롤은 각질세포막을 형성, 각질세포의 분화 촉진 및 천연보습인자를 생성함으로써 탁월한 보습기능이 있으므로 보습용 화장료 조성물, 식품 조성물 또는 약학적 조성물의 유효한 성분으로 이용될 수 있다. [화학식 1] ...

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Номер записи: 26
01-12-2016 дата публикации

COMPOSITION FOR PREVENTING AND TREATING MUSCLE DISEASES OR IMPROVING MUSCULAR FUNCTION, CONTAINING PLATYCODON GRANDIFLORUM EXTRACT

Номер: WO2016190683A1
Автор: HWANG, Jae-Kwan, KIM, Mi-Bo, KIM, Changhee, CHUNG, Heechul
Принадлежит:

The present invention relates to a composition for preventing and treating muscle diseases or improving muscular function, containing a Platycodon grandiflorum extract. More specifically, the present invention relates to: a pharmaceutical composition for preventing and treating muscle diseases, containing a Platycodon grandiflorum extract; a food composition for preventing muscle diseases or improving muscular function; or a cosmetic for improving muscular function. The Platycodon grandiflorum extract of the present invention increases muscle formation by inducing muscular protein synthesis and muscle cell differentiation. Therefore, the extract is a natural product so as to be used safely without side effects, thereby being usable as an active ingredient of a pharmaceutical, food, or cosmetic composition exhibiting an excellent effect in preventing and treating muscle diseases or improving muscular function.

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Номер записи: 27
12-09-2019 дата публикации

FUNCTIONAL FOOD COMPOSITION FOR ENHANCING MUSCULAR FUNCTION AND MOBILITY AND COMPRISING LOTUS LEAF EXTRACT, AND METHOD FOR PREPARING SAME

Номер: WO2019172712A1
Автор: KIM, Jin Hak, JANG, Ji Hwan, GEUM, Jeong Ho, KWEON, Min Son, CHOI, Su Young, KIM, Sang Woo, HWANG, Jae Kwan
Принадлежит:

The present invention relates to a functional food composition for enhancing muscular function and mobility and a method for preparing same. According to the present invention, provided is a composition which enables increased generation of factors associated with myogenesis and energy metabolism and thus enhances mobility and muscular function. More particularly, mitochondria and muscle cell synthesis is increased and muscular atrophy is inhibited, and thus muscle exercise effects can be increased and fatigue is reduced. The composition can be applied as a health function composition to various fields such as foods.

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Номер записи: 28
19-01-2017 дата публикации

판두라틴 유도체 또는 보에센베르기아 판두라타 추출물을 포함하는 근육 증가 촉진, 항-피로 및 운동수행능력 향상용 조성물

Номер: KR0101698201B1
Автор: 황재관, 김도언
Принадлежит: (주)뉴트리, (주)앗코스텍

... 본 발명은 판두라틴 유도체 또는 이의 염 또는 보에센베르기아 판두라타 추출물을 유효성분으로 포함하는 근육 증가 촉진, 항-피로 및 운동수행능력 향상용 조성물에 관한 것으로, 보다 상세하게는 4-히드록시판두라틴 A, 판두라틴 A 및 이소판두라틴 A로 이루어진 군에서 선택된 판두라틴 유도체 또는 이의 염 또는 보에센베르기아 판두라타 추출물을 유효성분으로 포함하는 근육 증가, 피로 회복 및 운동량 증가 효과를 가지는 운동수행능력 향상용 조성물에 관한 것이다. 본 발명의 판두라틴 유도체 또는 보에센베르기아 판두라타 추출물은 부작용 없이 안전하게 사용할 수 있고, 근육 내 PPARδ의 발현을 증가시켜 근육량 증가, 피로회복 및 운동성 증가 등 운동수행능력 향상에 우수한 효과를 가진다.

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Номер записи: 29
08-10-2015 дата публикации

COMPOSITION CONTAINING ALLIUM HOOKERI EXTRACT AS ACTIVE INGREDIENT FOR ENHANCING EXERCISE PERFORMANCE CAPABILITY

Номер: KR1020150113702A
Автор: HWANG, JAE KWAN, KIM, MI BO, SONG, YOUNG WOO, KU, HA RA
Принадлежит:

The present invention relates to a novel use of an Allium hookeri extract. More specifically, the present invention relates to a composition for enhancing an exercise performance capability, which contains an Allium hookeri extract. The Allium hookeri extract shows an excellent effect in improving an exercise performance capability by increasing the binding expression amount of PGC-1α and SIRT1 which are main factors in charge of biosynthesis of mitochondria. Accordingly, the Allium hookeri extract is a natural material to be safely used without side effects, and can be used as a useful component of a food and pharmaceutical composition having an excellent effect in improving exercise performance capability. COPYRIGHT KIPO 2016 (AA) Relative expression amount of PGC -1 α binding activity (BB) Control group (CC) Allium hookeri extract (ppm) ...

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Номер записи: 30
30-12-2015 дата публикации

ANTI-PERIODONTITIS COMPOSITION COMPRISING FLAVONE COMPOUNDS OR KAEMPFERIA PARVIFLORA EXTRACTS

Номер: KR1020150145332A
Автор: HWANG, JAE KWAN, SONG, YOUNG WOO
Принадлежит:

The present invention relates to a composition for preventing, alleviating, or treating periodontitis containing kaempferia parviflora extracts or fractions thereof as an active ingredient, and a composition for preventing, alleviating, or treating periodontitis containing at least one flavone compounds selected from a group comprising compounds expressed as chemical formula 1 to 3 or pharmaceutically acceptable salts thereof as an active ingredient. The active ingredients can be effectively used for managing oral and periodontal diseases by suppressing generation of collagen-degrading enzymes and bone resorption enzymes. COPYRIGHT KIPO 2016 (AA) kaempferia parviflora ethanol extract (μg/ml) ...

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Номер записи: 31
13-02-2018 дата публикации

COMPOSITION FOR PREVENTING MUSCLE DAMAGE AND IMPROVING MUSCULAR FUNCTIONS CONTAINING SQUALENE

Номер: KR1020180015594A
Автор: HWANG, JAE KWAN, LEE, SE IN, KIM, MI BO, KIM, CHANG HEE
Принадлежит:

The present invention relates to a composition for regenerating damaged muscles or preventing, treating, and ameliorating muscle disease containing squalene. More specifically, squalene increases expression of proteins associated with an increase in muscle mass, and synthesis of myoprotein in muscle cells, inhibits expression of enzymes involved in degradation of myoprotein at an mRNA level, and also quickly helps recover damaged muscles. In addition, squalene is derived from nature, is safe without side effects, and can be used as cosmetic products, foods, or drugs. COPYRIGHT KIPO 2018 (AA) Squalene ...

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Номер записи: 32
01-12-2016 дата публикации

COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING MUSCLE DISEASES OR IMPROVING MUSCULAR FUNCTION

Номер: WO2016190689A3
Автор: HWANG, Jae Kwan, KIM, Chang Hee, KIM, Mi-Bo
Принадлежит:

The present invention relates to a composition for preventing or treating muscle diseases or improving muscular function, containing fucosterol, Sargassum fulvellum, a Sargassum fulvellum ground product, a Sargassum fulvellum extract, Sargassum fusiforme, a Sargassum fusiforme ground product or a Sargassum fusiforme extract. According to the present invention, fucosterol, Sargassum fulvellum, a Sargassum fulvellum ground product, a Sargassum fulvellum extract, Sargassum fusiforme, a Sargassum fusiforme ground product or a Sargassum fusiforme extract increases the protein expression of p-mTOR, which is a main gene involved in muscle protein synthesis, inhibits the mRNA expression of MuRF-1 and atrogin-1 involved in muscle protein degradation, and increases the mRNA expression of MyoD and myogenin involved in muscle differentiation, thereby having an effect of remarkably increasing muscular function. In addition, since the composition of the present invention is a natural product, the composition ...

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Номер записи: 33
24-11-2011 дата публикации

NOVEL USE OF PANDURATIN DERIVATIVES OR AN EXTRACT OF BOESENBERGIA PANDURATA FOR PROMOTING MUSCLE MASS GROWTH, FIGHTING FATIGUE, AND ENHANCING EXERCISE PERFORMANCE CAPABILITY

Номер: WO2011145909A3
Автор: HWANG, Jae-Kwan, KIM, Do Un
Принадлежит:

The present invention relates to the novel use of panduratin derivatives or an extract of Boesenbergia pandurata for promoting muscle mass growth, fighting fatigue, and enhancing exercise performance capability. More particularly, the present invention relates to a composition for enhancing exercise performance capability, promoting muscle mass growth, and fighting fatigue, which comprises panduratin derivatives or salts thereof, or an extract of Boesenbergia pandurata, as active ingredients, and which promotes muscle mass growth and recovery from fatigue to improve mobility. The present invention also relates to a method for improving exercise performance capability, promoting muscle mass growth, and fighting fatigue, which involves injecting panduratin derivatives or salts thereof, or an extract of Boesenbergia pandurata, into an individual requiring same. The panduratin derivatives or the extract of Boesenbergia pandurata of the present invention can be used safely with no adverse effects ...

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Номер записи: 34
10-07-2018 дата публикации

COMPOSITION CONTAINING 3, 5-DICAFFEOYLQUINIC ACID OR CHRYSANTHEMUM EXTRACT FOR PREVENTING OR TREATING MUSCULAR DISEASES OR IMPROVING MUSCULAR FUNCTIONS

Номер: KR1020180079174A
Автор: HWANG JAE KWAN, YUN JUN GON, KIM MI BO, KIM CHANG HEE, LEE JOON HYUNG, KWON JIN HYOUK, YOON MANN SEOK, LEE JIN WOO, LIM JAE YOUN, KO DONG HYEON, DOWAN KWON
Принадлежит:

The present invention relates to a composition containing a chrysanthemum extract and 3, 5-dicaffeoylquinic acid as active ingredients for preventing or treating muscular diseases, and more specifically, to a composition which reduces expression of mRNA of atrogin-1 and MuRF-1, which are major biomarkers involved in muscle protein degradation in muscle cells, and reduces muscle loss by increasing expression of an mTOR protein, which is a major biomarker involved in formation of a muscle protein, and expression of mRNA of myogenin and MyoD, which are biomarkers related to muscle differentiation, thereby being used for preventing and treating muscular diseases, or improving muscular functions. In addition, the chrysanthemum extract or 3, 5-dicaffeoylquinic increases activity of SIRT1 and PCG-1α, which are major biomarkers involved in exercise performance, thereby remarkably improving exercise performance. In addition, the composition of the present invention is a natural material and can ...

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Номер записи: 35
12-09-2019 дата публикации

FUNCTIONAL FOOD COMPOSITION FOR ENHANCING MUSCULAR FUNCTION AND MOBILITY AND COMPRISING CHAMOMILE EXTRACT, AND METHOD FOR PREPARING SAME

Номер: WO2019172714A1
Автор: KIM, Jin Hak, JANG, Ji Hwan, GEUM, Jeong Ho, KWEON, Min Son, CHOI, Su Young, KIM, Sang Woo, HWANG, Jae Kwan
Принадлежит:

The present invention relates to a functional food composition for enhancing muscular function and mobility and a method for preparing same. According to the present invention, provided is a composition which enables increased generation of factors associated with myogenesis and energy metabolism and thus enhances mobility and muscular function. More particularly, mitochondria and muscle cell synthesis is increased and muscular atrophy is inhibited, and thus muscle exercise effects can be increased and fatigue is reduced. The composition can be applied as a health function composition to various fields such as foods.

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Номер записи: 36
26-07-2012 дата публикации

NOVEL USE OF FLAVONE-BASED COMPOUND

Номер: WO2012099449A3
Автор: HWANG, Jae-Kwan, KIM, Jaekyung
Принадлежит:

The present invention relates to a novel use of a flavone-based compound or Kaempferia parviflora extract, and more particularly, to a composition for anti-wrinkle, anti-aging and improvement of skin elasticity, comprising a flavone-based compound or Kaempferia parviflora extract, as an active ingredient. The composition of the present invention has superior effects of inhibiting collagenases and promoting collagen production, and therefore, may be effective in preventing skin wrinkles and aging and improving skin elasticity, and has superior effects of inhibiting loss of skin moisture and thus is effective in skin moisturizing.

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Номер записи: 37
01-12-2016 дата публикации

COMPOSITION FOR PREVENTING AND TREATING MUSCLE DISEASES OR IMPROVING MUSCULAR FUNCTION, CONTAINING MORUSIN, KUWANON G, OR MORI CORTEX RADICIS

Номер: WO2016190682A3
Автор: HWANG, Jae-Kwan, KIM, Mi-Bo, KIM, Changhee, KIM, Doun, CHUNG, Heechul
Принадлежит:

The present invention relates to a composition for preventing and treating muscle diseases or improving muscular function, containing, as an active ingredient, at least one selected from the group consisting of morusin, kuwanon G, and a Mori Cortex Radicis extract. The Mori Cortex Radicis extract, morusin, or kuwanon G, according to the present invention, has an effect of remarkably enhancing muscular function by increasing the expression of p-mTOR protein involved in muscular protein synthesis, inhibiting the expression of mRNAs of MuRF-1 and atrogin-1 involved in muscular protein degradation, and increasing the expression of mRNAs of MyoD and myogenin involved in muscle differentiation. In addition, the present invention is a natural product so as to be used safely without side effects, thereby being usable in drugs, food, or cosmetics.

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Номер записи: 38
06-12-2016 дата публикации

COMPOSITION FOR PREVENTING, IMPROVING OR TREATING MUSCULAR DISEASES OR FOR IMPROVING MUSCULAR FUNCTIONS

Номер: KR1020160138926A
Автор: HWANG, JAE KWAN, KIM, MI BO, KIM, CHANG HEE
Принадлежит:

The present invention relates to a composition for preventing or treating muscular diseases or for improving muscular functions, which comprises fucosterol, Sargassum fulvellum, pulverized Sargassum fulvellum, a Sargassum fulvellum extract, Hijikia fusiforme Okamura, pulverized Hijikia fusiforme Okamura or a Hijikia fusiforme Okamura extract. According to the present invention, the fucosterol, the Sargassum fulvellum, the pulverized Sargassum fulvellum, the Sargassum fulvellum extract, the Hijikia fusiforme Okamura, the pulverized Hijikia fusiforme Okamura or the Hijikia fusiforme Okamura extract increases expression of protein of the main genes p-mTOR involved in synthesis of muscular protein, inhibits expression of mRNA of MuRF-1 and atrogin-1 involved in decomposition of muscular protein and increases expression of mRNA of MyoD and myogenin involved in muscular differentiation, and thus enhances muscular functions significantly. In addition, the composition according to the present invention ...

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Номер записи: 39
01-12-2016 дата публикации

COMPOSITION FOR PREVENTING AND TREATING MUSCLE DISEASES OR IMPROVING MUSCULAR FUNCTION, CONTAINING PLATYCODON GRANDIFLORUM EXTRACT

Номер: WO2016190683A8
Автор: HWANG, Jae-Kwan, KIM, Mi-Bo, KIM, Changhee, KIM, Doun, CHUNG, Heechul
Принадлежит:

The present invention relates to a composition for preventing and treating muscle diseases or improving muscular function, containing a Platycodon grandiflorum extract. More specifically, the present invention relates to: a pharmaceutical composition for preventing and treating muscle diseases, containing a Platycodon grandiflorum extract; a food composition for preventing muscle diseases or improving muscular function; or a cosmetic for improving muscular function. The Platycodon grandiflorum extract of the present invention increases muscle formation by inducing muscular protein synthesis and muscle cell differentiation. Therefore, the extract is a natural product so as to be used safely without side effects, thereby being usable as an active ingredient of a pharmaceutical, food, or cosmetic composition exhibiting an excellent effect in preventing and treating muscle diseases or improving muscular function.

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Номер записи: 40
08-10-2015 дата публикации

COMPOSITION FOR SKIN WHITENING CONTAINING ALLIUM HOOKERI EXTRACT AS ACTIVE INGREDIENT

Номер: KR1020150113709A
Автор: HWANG, JAE KWAN, LEE, SUN AH, RHIM, DONG BIN
Принадлежит:

The present invention relates to a novel use of an Allium hookeri extract and, more specifically, to a composition for skin whitening containing an Allium hookeri extract. The Allium hookeri extract exhibits excellent whitening effects by inhibiting an activity of tyrosinase and production of melanin, thereby being applied for an active ingredient in a cosmetic composition for skin whitening, a food composition, or a pharmaceutical composition. COPYRIGHT KIPO 2016 (AA) Melanin contents in comparison with a control group(%) (BB) Specimen (CC) Allium hookeri extract (µg/ml) ...

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Номер записи: 41
10-08-2017 дата публикации

모루신, 구와논 지 또는 상백피를 함유하는 근육 질환 예방 및 치료용 또는 근 기능 개선용 조성물

Номер: KR0101767248B1
Автор: 황재관, 김미보, 김창희, 김도언, 정희철
Принадлежит: (주)뉴트리

... 본 발명은 모루신(morusin), 구와논 지(kuwanon G) 및 상백피(Mori Cortex Radicis) 추출물로 이루어진 군에서 선택된 하나 이상을 유효성분으로 포함하는 근육 질환 예방 및 치료용 또는 근 기능 개선용 조성물에 관한 것이다. 본 발명에 따른 상백피 추출물, 모루신, 또는 구와논 지는 근 단백질 합성에 관여하는 p-mTOR의 단백질 발현 증가, 근 단백질 분해에 관여하는 MuRF-1과 atrogin-1의 mRNA 발현 억제, 근육 분화에 관여하는 MyoD와 myogenin의 mRNA 발현을 증가시킴에 따라, 근 기능을 탁월하게 증강하는 효과가 있다. 또한, 본 발명은 천연물이므로 부작용 없이 안전하게 사용될 수 있어, 의약품, 식품 또는 화장품으로 사용될 수 있다.

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Номер записи: 42
22-09-2016 дата публикации

잔소리졸을 유효성분으로 함유하는 당뇨 예방 및 치료용 조성물

Номер: KR0101658873B1
Автор: 황재관, 조근애, 김대영, 한성화
Принадлежит: 주식회사 뉴트리사이언스

... 본 발명은 잔소리졸을 함유하는 당뇨 예방 및 치료용 조성물에 관한 것으로 잔소리졸은 AMPK 효소를 활성화시킴으로서 포도당의 세포 내 흡수를 유도하여 혈당강하 효능이 우수하며, 당뇨병의 예방, 억제 및 치료에 우수한 효능을 갖는 식품, 의약품 및 사료첨가제로서 유용하다.

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Номер записи: 43
10-11-2017 дата публикации

COMPOSITION FOR PREVENTION AND TREATMENT OF MUSCULAR DISORDERS OR IMPROVEMENT OF MUSCULAR FUNCTIONS COMPRISING EXTRACTS OF AMARANTH OR CEREALS

Номер: KR1020170124426A
Автор: HWANG, JAE KWAN, LEE, SE IN, KIM, MI BO, KIM, CHANG HEE
Принадлежит:

The present invention relates to a composition for prevention and treatment of muscular disorders or the improvement of muscular functions comprising extracts of amaranth or cereals as an effective component. More particularly, the present invention relates to a pharmaceutical composition for the prevention and treatment of muscular disorders containing extracts of amaranth or cereals, to health functional food for the prevention and treatment of muscular disorders, and to a cosmetic composition for improving muscular functions. COPYRIGHT KIPO 2017 (AA) Control group (BB) Ethanol extract of amaranth 1 μg/ ml (CC) Ethanol extract of amaranth 10 μg/ ml ...

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Номер записи: 44
08-10-2015 дата публикации

COMPOSITION CONTAINING ALLIUM HOOKERI EXTRACT AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING OSTEOPOROSIS

Номер: KR1020150113687A
Автор: HWANG, JAE KWAN, KIM, MI BO, KIM, CHANG HEE
Принадлежит:

The present invention relates to a composition for preventing and treating/alleviating osteoporosis, which contains an Allium hookeri extract as an active ingredient. The Allium hookeri extract of the present invention increases expression of osteoblast differentiation adjustment genes (ALP and ColA1) to exhibit excellent effects of preventing and treating osteoporosis. Accordingly, the composition is a natural material, thereby being safely used without side effects. Osteoblast differentiation genes are adjusted, so the composition exhibits an excellent effect of preventing and treating/alleviating osteoporosis. COPYRIGHT KIPO 2016 (AA) Allium hookeri extract (ppm) ...

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Номер записи: 45
21-01-2016 дата публикации

COMPOSITION COMPRISING KIRENOL OR EXTRACT OF SIGESBECKIA SPP. FOR INCREASING FUNCTION OF MUSCLES

Номер: KR1020160008109A
Автор: HWANG, JAE KWAN, KIM, MI BO, KIM, CHANG HEE
Принадлежит:

The present invention relates to a composition comprising kirenol, an extract of Siegebeckia spp. (Huichum) containing the same, or a fraction of the same as an active component for increasing the function of muscles. The kirenol, an extract of Siegebeckia spp. containing the same, or a fraction of the same increases the function of muscle by increasing protein expression of a main gene p-mTOR involved in the function of muscles. The composition in the present invention is a natural material, thereby being safely used without side effects, and being used as a medicine or food. COPYRIGHT KIPO 2016 (AA) Control group (BB) Siegebeckia glabrescens 10ppm (CC) Siegebeckia pubescens 10ppm (DD) Siegebeckia orientalis 10ppm (EE) Kirenol 10µM ...

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Номер записи: 46
27-12-2016 дата публикации

COMPOSITION CONTAINING ALLIUM HOOKERI EXTRACT FOR IMPROVING EXERCISE CAPACITY

Номер: KR1020160148886A
Автор: HWANG, JAE KWAN, KIM, CHANG HEE
Принадлежит:

The present invention relates to a composition containing an Allium hookeri extract as an active ingredient for improving exercise capacity. The Allium hookeri extract according to the present invention enhances expression and activation of PGC-1alpha protein and mRNA, thereby excellently enhancing exercise capacity. Also, the present invention uses a natural product which can be used safely without side effects, thereby being used as a pharmaceutical product or a food product. COPYRIGHT KIPO 2017 (AA) Control group (BB) Allium hookeri root ethanol extract ...

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Номер записи: 47
24-11-2011 дата публикации

NOVEL USE OF PANDURATIN DERIVATIVES OR AN EXTRACT OF BOESENBERGIA PANDURATA FOR PROMOTING MUSCLE MASS GROWTH, FIGHTING FATIGUE, AND ENHANCING EXERCISE PERFORMANCE CAPABILITY

Номер: WO2011145909A2
Автор: HWANG, Jae-Kwan, KIM, Do Un
Принадлежит:

The present invention relates to the novel use of panduratin derivatives or an extract of Boesenbergia pandurata for promoting muscle mass growth, fighting fatigue, and enhancing exercise performance capability. More particularly, the present invention relates to a composition for enhancing exercise performance capability, promoting muscle mass growth, and fighting fatigue, which comprises panduratin derivatives or salts thereof, or an extract of Boesenbergia pandurata, as active ingredients, and which promotes muscle mass growth and recovery from fatigue to improve mobility. The present invention also relates to a method for improving exercise performance capability, promoting muscle mass growth, and fighting fatigue, which involves injecting panduratin derivatives or salts thereof, or an extract of Boesenbergia pandurata, into an individual requiring same. The panduratin derivatives or the extract of Boesenbergia pandurata of the present invention can be used safely with no adverse effects ...

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Номер записи: 48
03-08-2016 дата публикации

ANTI-OBESITY COMPOSITION COMPRISING SIEGESBECKIA ORIENTALIS L. EXTRACT

Номер: KR1020160091869A
Автор: HWANG, JAE KWAN, KIM, MI BO, KIM, TAE YOON
Принадлежит:

The present invention relates to a composition for preventing, alleviating, or treating obesity, comprising a Siegesbeckia orientalis L. extract as an active ingredient. According to the present invention, a fraction thereof reduces the expression of main transcription factors (PPARγ, C/EBPα, and SREBP-1c) related to the differentiation of adipocytes inside the adipocytes, thereby having excellent effects with respect to the obesity. In addition, the composition of the present invention as a natural substance can be safely used without side effects, and can be used as a drug or a food. COPYRIGHT KIPO 2016 (AA) Weight (g) (BB) Feeding period (weeks) of an experimental diet (CC) Control group fed with a normal diet (DD) Normal diet + a Siegesbeckia orientalis L. ethanol extract (EE) Control group fed with a high-fat diet (FF) High-fat diet + the Siegesbeckia orientalis L. ethanol extract ...

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Номер записи: 49
21-01-2016 дата публикации

COMPOSITION COMPRISING KIRENOL OR EXTRACT OF SIGESBECKIA SPP. FOR INCREASING EXERCISE CAPACITY

Номер: KR1020160008108A
Автор: HWANG, JAE KWAN, KIM, MI BO, KIM, CHANG HEE
Принадлежит:

The present invention relates to a composition comprising kirenol or Siegesbeckia spp. (Huichum) containing the same for increasing exercise capacity. The kirenol, Siegesbeckia spp. extract containing the same, or a fraction of the same increases exercise capacity by increasing protein expression of main genes involved in exercise capacity. Also, the composition in the present invention is a natural material, thereby being safely used without side effects, and being used as a medicine or food. COPYRIGHT KIPO 2016 (AA) Control group (BB) Siegesbeckia glabrescens 10ppm (CC) Siegesbeckia pubescens 10ppm (DD) Siegesbeckia orientalis 10ppm (EE) Kirenol 10µM ...

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Номер записи: 50
01-12-2016 дата публикации

COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING MUSCLE DISEASES OR IMPROVING MUSCULAR FUNCTION

Номер: WO2016190689A2
Автор: HWANG, Jae Kwan, KIM, Chang Hee, KIM, Mi-Bo
Принадлежит:

The present invention relates to a composition for preventing or treating muscle diseases or improving muscular function, containing fucosterol, Sargassum fulvellum, a Sargassum fulvellum ground product, a Sargassum fulvellum extract, Sargassum fusiforme, a Sargassum fusiforme ground product or a Sargassum fusiforme extract. According to the present invention, fucosterol, Sargassum fulvellum, a Sargassum fulvellum ground product, a Sargassum fulvellum extract, Sargassum fusiforme, a Sargassum fusiforme ground product or a Sargassum fusiforme extract increases the protein expression of p-mTOR, which is a main gene involved in muscle protein synthesis, inhibits the mRNA expression of MuRF-1 and atrogin-1 involved in muscle protein degradation, and increases the mRNA expression of MyoD and myogenin involved in muscle differentiation, thereby having an effect of remarkably increasing muscular function. In addition, since the composition of the present invention is a natural product, the composition ...

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Номер записи: 51
06-12-2016 дата публикации

COMPOSITION FOR PREVENTING AND TREATING MUSCULAR DISEASES OR FOR IMPROVING MUSCULAR FUNCTIONS COMPRISING MORUSIN, KUWANON G OR MORI CORTEX RADICIS

Номер: KR1020160138929A
Автор: HWANG, JAE KWAN, KIM, MI BO, KIM, CHANG HEE, KIM, DO UN, CHUNG, HEE CHUL
Принадлежит:

The present invention relates to a composition for preventing or treating muscular diseases or for improving muscular functions, which comprises at least one selected from the group consisting of morucin, kuwanon G and Mori Cortex Radicis extract as an active ingredient. According to the present invention, Mori Cortex Radicis extract, morucin or kuwanon G increases expression of protein of the main genes p-mTOR involved in synthesis of muscular protein, inhibits expression of mRNA of MuRF-1 and atrogin-1 involved in decomposition of muscular protein and increases expression of mRNA of MyoD and myogenin involved in muscular differentiation, and thus enhances muscular functions significantly. In addition, the composition according to the present invention comprises naturally occurring materials and can be used safely without side effects, and thus can be useful for pharmaceuticals, foods, cosmetics, livestock feed or feed additives. COPYRIGHT KIPO 2016 (AA) Control group (BB) Morucin 5μM ...

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Номер записи: 52
30-08-2017 дата публикации

COMPOSITION FOR TREATING, PREVENTING OR REDUCING BORN LOSS DISEASE COMPRISING XANTHORRHIZOL OR CURCUMA XANTHORRHIZA EXTRACT

Номер: KR101772804B1
Автор: HWANG, JAE KWAN, KIM, SI YEON, KIM, MI BO
Принадлежит: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

The present invention relates to a composition comprising a xanthorrhizol or Curcuma xanthorrhiza extract as an active ingredient, wherein the composition has an effect of inhibiting osteoclast differentiation and treating, preventing or reducing bone loss diseases, and as a natural product, can be safely used without side effects, thereby being effectively used for medicines, quasi-drugs or food. COPYRIGHT KIPO 2017 ...

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Номер записи: 53
02-11-2018 дата публикации

퓨코스테롤을 유효성분으로 포함하는 피부 보습용 화장료 조성물

Номер: KR0101914441B1
Автор: 황재관
Принадлежит: (주)앗코스텍

... 본 발명은 퓨코스테롤의 새로운 용도에 관한 것으로, 더욱 상세하게는 퓨코스테롤을 유효성분으로 포함하는 피부주름 또는 피부노화 개선용 화장료 조성물에 관한 것이다. 본 발명의 조성물은 콜라겐 분해효소를 억제하고, 콜라겐의 생성을 촉진하는 효능이 뛰어나 피부의 노화 개선 및 피부보습력 증진에 효과적이다.

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Номер записи: 54
20-11-2015 дата публикации

ANTI-OBESITY COMPOSITION INCLUDING JAVA TURMERIC POLYSACCHARIDES

Номер: KR1020150129343A
Автор: HWANG, JAE KWAN
Принадлежит:

The present invention relates to an anti-obesity composition, and more specifically, to a new usage of a composition containing java turmeric polysaccharides, wherein the java turmeric polysaccharides provide a food composition or a pharmaceutical composition with an anti-obesity activity by reducing weight and body fat. COPYRIGHT KIPO 2016 (AA) Weight (g) (BB) High fat diet (HFD) (CC) High fat diet (HFD)+Polysaccharide complex ...

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Номер записи: 55
06-12-2012 дата публикации

COMPOSITION FOR TREATING OBESITY AND DIABETES AND FOR INCREASING MUSCLE MASS AND IMPROVING CAPACITY FOR EXERCISE, COMPRISING EXTRACTS OF PIPER RETROFRACTUM VAHL. FRUITS AS ACTIVE INGREDIENTS

Номер: WO2012165888A3
Автор: KIM, Kyung-Jin, KIM, Min-Sun, HWANG, Jae-Kwan
Принадлежит:

The present invention relates to a food composition, and to a pharmaceutical composition, which exhibit anti-obesity effects by means of a thermogenesis produced by an activity of a UCP of fat cells, which exhibit anti-diabetes effects by means of an improved insulin resistance, increase muscle mass, and improve capacity for exercise. More particularly, the present invention relates to a novel use of a composition containing extracts of piper retrofractum, and to the food composition or pharmaceutical composition which exhibit anti-obesity effects by means of decreased body weight and body fat, exhibit anti-diabetes effects by means of ameliorated insulin resistance through the reduction of blood glucose and blood insulin, increase muscle mass by increasing an energy source being supplied to the muscles, and improve the capacity for exercise including increased endurance.

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Номер записи: 56
05-07-2018 дата публикации

COMPOSITION FOR PREVENTION AND TREATMENT OF MUSCULAR DISEASES OR FOR IMPROVEMENT OF MUSCLE FUNCTION CONTAINING 3,5-DICAFFEOYLQUINIC ACID OR CHRYSANTHEMUM EXTRACT

Номер: WO2018124508A1
Автор: HWANG, Jae Kwan, YUN, Jun Gon, KIM, Mi Bo, KIM, Chang Hee, LEE, Joon Hyung, KWON, Jin Hyouk, YOON, Mann Seok, LEE, Jin Woo, LIM, Jae Youn, KO, Dong Hyeon, KWON, Do Wan
Принадлежит:

The present invention relates to a composition for preventing or treating muscular diseases, which contains an extract of chrysanthemum and 3,5-dicaffeoylquinic acid as active ingredients. Specifically, since the present invention reduces mRNA expression of atrogin-1 and MuRF-1, which are major biomarkers involved in muscle protein degradation in muscle cells, and reduces muscle loss by increasing mRNA expression of mTOR protein, which is a major biomarker involved in muscle protein formation, and myogenin and MyoD, which are biomarkers associated with muscle differentiation, the present invention can be used for preventing and treating muscular diseases or improving muscle function. In addition, the chrysanthemum extract or the 3,5-dicaffeoylquinic acid has an effect of excellently improving exercise performance by increasing the activity of SIRT1 and PCG-1α which are major biomarkers involved in exercise performance. Moreover, since the present invention is a natural product, the present ...

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Номер записи: 57
06-10-2016 дата публикации

COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING OSTEOPOROSIS, CONTAINING SIEGESBOCKIA HERB EXTRACT

Номер: KR1020160115889A
Автор: HWANG, JAE KWAN, KIM, MI BO, SONG, YOUNG WOO
Принадлежит:

The present invention relates to a composition for preventing, ameliorating, or treating osteoporosis, containing a Sigesbeckia orientalis (Hui Chum,Siegesbeckiaspp.) extract as an active ingredient. According to the present invention, the siegesbockia herb extract or a fraction thereof can promote differentiation of osteoblast, and inhibits production of osteoclast, thereby preventing, ameliorating, and treating osteoporosis. In addition, the composition contains natural ingredients, and thus is safe without side effects, thereby being useful as drugs or foods. COPYRIGHT KIPO 2016 (AA) Control group (BB) Siegesbeckia orientalis 10 ppm (CC) Siegesbeckia glabrescens 10 ppm (DD) Siegesbeckia pubescens 10 ppm ...

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Номер записи: 58
07-09-2017 дата публикации

COMPOSITION FOR TREATING, PREVENTING OR ALLEVIATING BONE LOSS CONTAINING PANDURATIN OR FINGERROOT (BOESENBERGIA PANDURATA) EXTRACT

Номер: KR101776001B1
Автор: HWANG, JAE KWAN, KIM, SI YEON, KIM, MI BO
Принадлежит: NEWTREE CO., LTD.

The present invention relates to a composition for treating, preventing or alleviating bone loss containing panduratin or a fingerroot (Boesenbergia pandurata) extract as an effective component. The composition inhibits osteoclast differentiation, thereby having a therapeutic, preventive or ameliorative effect on bone loss; and can be safely used as a natural product without side effects, so that the composition can be effectively used for medicines, quasi-drugs or foods. COPYRIGHT KIPO 2017 ...

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Номер записи: 59
30-12-2015 дата публикации

COMPOSITION FOR IMPROVING MUSCULAR FUNCTION OR ENHANCING EXERCISE PERFORMANCE, CONTAINING KIRENOL OR HUI CHUM EXTRACT

Номер: WO2015199516A1
Автор: HWANG, Jae-Kwan, KIM, Mi-Bo, KIM, Chang Hee
Принадлежит:

The present invention relates to a composition improving a muscular function or enhancing an exercise performance, the composition containing, as an active ingredient, kirenol, a Hui Chum (Siegesbeckia spp.) extract containing the same, or a fraction thereof. The kirenol, the Hui Chum (Siegesbeckia spp.) extract containing the same, or the fraction thereof, according to the present invention, increases the protein expression of p-mTOR, which is a main gene involved in the muscular function, thereby significantly enhancing the muscular function. The kirenol, the Hui Chum (Siegesbeckia spp.) extract containing the same, or the fraction thereof, according to the present invention, increases the protein expression of PGC-1α, which is a main gene involved in the exercise performance, thereby significantly enhancing the exercise performance. Furthermore, the present invention can be safely used without side effects since it is a natural material, and thus can be used as a medicinal product or ...

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Номер записи: 60
08-10-2015 дата публикации

SKIN ANTI-AGING COMPOSITION CONTAINING ALLIUM HOOKERI EXTRACT AS ACTIVE INGREDIENT

Номер: KR1020150113717A
Автор: HWANG, JAE KWAN, JEONG, JAE HONG, WOO, SEON WOOK
Принадлежит:

The present invention relates to a novel use of an Allium hookeri extract and, more specifically, to a composition for wrinkle amelioration and anti-aging containing an Allium hookeri extract. The Allium hookeri extract inhibits degradation of collagen, stimulates collagen synthesis, and thus exhibits excellent anti-aging activities and outstanding effects of ameliorating, preventing, or treating wrinkles, thereby being used as an active ingredient in a cosmetic composition, a food composition, or a pharmaceutical composition. COPYRIGHT KIPO 2016 (A1,A2) Extract (µg/ml) (B1,B2) Ultraviolet ray (20mJ/cm^2) (C1) Collagenase-1 (C2) Collagenase-1 mRNA ...

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Номер записи: 61
11-08-2016 дата публикации

플라본계 화합물 또는 캠페리아 파비플로라 추출물을 함유하는 치주질환 개선 조성물

Номер: KR0101647495B1
Автор: 황재관, 송영우
Принадлежит: 연세대학교 산학협력단

... 본 발명은 캠페리아 파비플로라 (Kaempferia parviflora) 추출물 또는 이의 분획물을 유효성분으로 포함하는 치주질환의 예방, 개선 또는 치료용 조성물, 및 하기 화학식 1 내지 3으로 표시되는 화합물로 이루어진 군으로부터 선택된 하나 이상의 플라본계 화합물 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 치주질환의 예방, 개선 또는 치료용 조성물에 관한 것으로, 이들 유효성분은 교원질 분해효소 및 골흡수효소의 생성을 억제하여 치주질환 및 구강 관리에 매우 유용하게 사용될 수 있다: [화학식 1] ,[화학식 2] , 및[화학식 3] .

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Номер записи: 62
02-07-2020 дата публикации

COMPOSITION FOR PREVENTING AND TREATING MUSCLE DISEASE OR IMPROVING MUSCLE FUNCTION, COMPRISING ILLICIUM VERUM EXTRACT OR SHIKIMIC ACID

Номер: WO2020139057A2
Автор: HWANG, Jae Kwan, KIM, Changhee, YOO, Ji Hee
Принадлежит:

The present invention relates to a composition for preventing and treating a muscle disease or improving muscle function, comprising an Illicium verum extract and shikimic acid. The Illicium verum extract and shikimic acid according to the present invention have the effect of increasing activity of mTOR involved in muscle protein synthesis and reducing the mRNA expression of MuRF-1 and atrogin-1 involved in muscle protein degradation, and increase muscle mass and enhance muscle function, thereby being useful for preventing, treating, or alleviating various muscle diseases such as atony, muscular atrophy, muscular dystrophy, muscular degeneration, myasthenia, cachexia, and sarcopenia.

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Номер записи: 63
25-07-2018 дата публикации

Composition for enhancing muscle function and exercise capacity comprising Vigna angularis

Номер: KR0101882006B1
Автор: 황재관, 이세인, 김미보, 김창희, 김도언, 정희철, 김형민
Принадлежит: (주)뉴트리

... 본 발명에 따른 팥은 근육의 기능, 근육량 증대 또는 근육세포의 분화에 관여하는 유전자의 mRNA 또는 단백질 발현 및 활성을 촉진시키는 효과를 통해서, 근육량의 증대, 근 기능 또는 운동수행능력의 향상을 가능하게 하고, 각종 질병에 의하여 유발되는 운동수행능력 저하, 근육의 기능 저하, 근육의 손실 등을 예방, 치료 또는 개선할 수 있으며, 천연물질로서 체내 부작용이 없어 의약품 또는 식품 등에 효과적으로 사용될 수 있다.

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Номер записи: 64
15-04-2010 дата публикации

NOVEL USE OF PANDURATIN DERIVATIVE OR BOESENBERGIA PANDURATA EXTRACT

Номер: KR2010041908A2
Автор: HWANG, Jae-Kwan
Принадлежит:

The present invention relates to a novel use of panduratin derivative or Boesenbergia pandurata extract. More specifically, the present invention relates to: a composition containing panduratin derivative or Boesenbergia pandurata extract denoted by chemical formulas 1 to 3 as an active ingredient for preventing and treating/relieving metabolic disease; a method for treating metabolic disease characterized by administering effective amount of panduratin derivative or Boesenbergia pandurata extract to a needed individual; a use of the panduratin derivative or Boesenbergia pandurata extract to manufacture a formulation for preventing and treating/relieving metabolic diseases. The metabolic disease is selected from the group consisting of obesity, hyperlipidemia, hypercholesterolemia, and diabetes. The present invention provides a novel use of the panduratin derivative or Boesenbergia pandurata extract. The panduratin derivative or Boesenbergia pandurata extract of the present invention has ...

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Номер записи: 65
01-12-2016 дата публикации

COMPOSITION FOR PREVENTING AND TREATING MUSCLE DISEASES OR IMPROVING MUSCULAR FUNCTION, CONTAINING MORUSIN, KUWANON G, OR MORI CORTEX RADICIS

Номер: WO2016190682A2
Автор: HWANG, Jae-Kwan, KIM, Mi-Bo, KIM, Changhee, KIM, Doun, CHUNG, Heechul
Принадлежит:

The present invention relates to a composition for preventing and treating muscle diseases or improving muscular function, containing, as an active ingredient, at least one selected from the group consisting of morusin, kuwanon G, and a Mori Cortex Radicis extract. The Mori Cortex Radicis extract, morusin, or kuwanon G, according to the present invention, has an effect of remarkably enhancing muscular function by increasing the expression of p-mTOR protein involved in muscular protein synthesis, inhibiting the expression of mRNAs of MuRF-1 and atrogin-1 involved in muscular protein degradation, and increasing the expression of mRNAs of MyoD and myogenin involved in muscle differentiation. In addition, the present invention is a natural product so as to be used safely without side effects, thereby being usable in drugs, food, or cosmetics.

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Номер записи: 66
30-12-2021 дата публикации

COMPOSITION FOR ALLEVIATING, TREATING, OR PREVENTING MUSCULAR DISEASES, OR IMPROVING MUSCULAR FUNCTIONS, CONTAINING KOREAN MINT EXTRACT OR TILIANIN AS ACTIVE INGREDIENT

Номер: WO2021261707A1
Автор: HWANG, Jae Kwan, KIM, Changhee, WOO, Yu Kyong
Принадлежит:

The present invention relates to a composition for alleviating, treating, or preventing muscular diseases, or improving muscular functions, containing, as an active ingredient, a Korean mint extract or tilianin. Korean mint or tilianin according to the present invention has effects of increasing the activity of mTOR, which is involved in muscle protein synthesis and reducing mRNA expression of MuRF-1 and atrogin-1 which are involved in muscle protein degradation, and increases muscle mass and improves muscle functions, and thus can be effectively used in preventing, treating or alleviating various muscular diseases, such as sarcopenia, muscular atrophy, muscular dystrophy, atony, muscle degeneration, myasthenia and cachexia.

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Номер записи: 67
21-11-2013 дата публикации

USE OF FLAVONE COMPOUND FOR PREVENTION OR TREATMENT OF OBESITY

Номер: WO2013172682A1
Автор: HWANG, Jae-Kwan, KIM, Myung Suk, OH, Ga Hui
Принадлежит:

The present invention relates to a pharmaceutical composition containing flavone compound as an active ingredient for treating obesity, and more specifically to a pharmaceutical composition for preventing or treating obesity and a dietary composition for preventing or reducing obesity containing 5,7-dimethoxyflavone or 5,7,4'-trimethoxyflavone. The compound according to the present invention inhibits adiopogenesis, and reduces expressions of the key transcription factors (SREBP1c and C/EBP) related to lipogenesis and of enzyme proteins (FAS and ACC) related to adiopogenesis, and thus is effective in preventing or treating obesity.

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Номер записи: 68
22-06-2018 дата публикации

커큐마 잔소리자 추출물 제조방법

Номер: KR0101870248B1
Автор: 권진혁, 윤만석, 이진우, 심재석, 박영민, 김진학, 성나혜, 황재관, 박진우, 최수영
Принадлежит: 주식회사 뉴트리사이언스

... 본 발명은 커큐마 잔소리자(Curcumaxanthorrhiza Roxb.) 추출물의 제조방법에 관한 것으로, 커큐마 잔소리자를 초임계 추출하여 잔소리졸을 유효성분으로 하는 추출물을 얻는 단계; 상기 초임계 추출 잔사를 주정 추출 또는 초임계 추출하여 커큐민을 유효성분으로 하는 추출물을 얻는 단계; 상기 주정 추출 또는 초임계 추출 잔사를 효소 처리하여 평균 분자량 33,000 Da인 면역다당을 얻는 단계; 상기 효소처리 잔사에서 불용성 식이섬유를 얻는 단계를 포함하는 것을 특징으로 하는 커큐마 잔소리자 추출물의 제조방법, 이러한 제조방법에 의해 얻어진 잔소리졸, 커큐민, 면역다당, 불용성 식이섬유를 포함하는 추출물, 이러한 추출물을 유효성분으로 포함하는 일반식품, 건강기능성식품, 화장품, 약학 등의 조성물을 제공한다. 본 발명에 따른 커큐마 잔소리자 추출법은 다양한 추출법을 단계적으로 적용하여 한가지 원료로부터 다양한 종류의 천연 추출물을 수득할 수 있어 천연물을 이용한 추출물 제조에 매우 유용하게 사용될 수 있다.

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Номер записи: 69
15-11-2017 дата публикации

COMPOSITION FOR INCREASING SECRETION OF SALIVA, OR PREVENTING, IMPROVING, OR TREATING XEROSTOMIA COMPRISING CURCUMA XANTHORRHIZA EXTRACT OR XANTHORRHIZOL

Номер: KR1020170125481A
Автор: HWANG, JAE KWAN, LEE, SUN KYU
Принадлежит:

The present invention relates to a composition comprising a Curcuma xanthorrhiza extract or xanthorrhizol, wherein the composition promotes the activity of genes and proteins associated with salivary secretion in salivary gland cells, increases intracellular Ca^2+ concentration to increase electrolyte secretion, so that it is possible to prevent, treat or ameliorate oral dryness or salivary secretion abnormality through enhancement of saliva secretion, and the composition of the present invention can be safely used as a natural product without side effects to be effectively used for the production of medicines, quasi-drugs or food, and the like. COPYRIGHT KIPO 2017 (AA) Curcuma xanthorrhiza extract (μg /mL) ...

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Номер записи: 70
28-04-2016 дата публикации

Composition containing Curcuma xanthorrhiza for preventing skin aging

Номер: KR0101615900B1
Автор: 조남훈, 김정기, 이지해, 김완기, 이상준, 황재관
Принадлежит: (주)아모레퍼시픽, 연세대학교 산학협력단

... 본 발명은 커큐마 잔소리자(Curcuma xanthorrhiza)를 유효성분으로 함유하는 피부 노화 방지용 조성물에 관한 것으로 더욱 상세하게는 커큐마 잔소리자(Curcuma xanthorrhiza)의 에탄올 추출물을 유효성분으로 하는 약학 조성물, 건강보조식품 및 화장품 조성물에 관한 것이다. 본 발명은 생약 추출물로 섭취 시 인체에 부작용이 없으면서 광노화 억제 작용으로 피부 노화를 방지하여 주름완화, 건조개선 등의 우수한 피부개선 효과가 있어 피부 광노화 예방 또는 개선용 건강보조식품 및 화장품으로 다양하게 이용할 수 있다.

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Номер записи: 71
12-05-2017 дата публикации

COSMETIC COMPOSITION FOR ALLEVIATING SKIN AGING OR SKIN MOISTURIZING, COMPRISING FUCOSTEROL AS ACTIVE INGREDIENT

Номер: KR1020170052556A
Автор: HWANG, JAE KWAN
Принадлежит:

The present invention relates to a novel use of fucosterol and, more specifically, to a cosmetic composition for alleviating skin wrinkles or skin aging, comprising fucosterol as an active ingredient. The composition of the present invention inhibits collagenase and has excellent efficacy of promoting the production of collagen, thereby being effective in alleviating skin aging and improving skin moisturizing power. COPYRIGHT KIPO 2017 (AA) MMP-1 biosynthesis (Comparison with a control group %) (BB) Sample (μ M) (CC) Fucosterol ...

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Номер записи: 72
06-12-2012 дата публикации

COMPOSITION FOR TREATING OBESITY AND DIABETES AND FOR INCREASING MUSCLE MASS AND IMPROVING CAPACITY FOR EXERCISE, COMPRISING EXTRACTS OF PIPER RETROFRACTUM VAHL. FRUITS AS ACTIVE INGREDIENTS

Номер: WO2012165888A9
Автор: KIM, Kyung-Jin, KIM, Min-Sun, HWANG, Jae-Kwan
Принадлежит:

The present invention relates to a food composition, and to a pharmaceutical composition, which exhibit anti-obesity effects by means of a thermogenesis produced by an activity of a UCP of fat cells, which exhibit anti-diabetes effects by means of an improved insulin resistance, increase muscle mass, and improve capacity for exercise. More particularly, the present invention relates to a novel use of a composition containing extracts of piper retrofractum, and to the food composition or pharmaceutical composition which exhibit anti-obesity effects by means of decreased body weight and body fat, exhibit anti-diabetes effects by means of ameliorated insulin resistance through the reduction of blood glucose and blood insulin, increase muscle mass by increasing an energy source being supplied to the muscles, and improve the capacity for exercise including increased endurance.

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Номер записи: 73
27-02-2018 дата публикации

모루신, 구와논 지 또는 상백피를 함유하는 근육 질환 예방 및 치료용 또는 근 기능 개선용 조성물

Номер: KR0101832897B1
Автор: 황재관, 김미보, 김창희, 김도언, 정희철
Принадлежит: (주)뉴트리

... 본 발명은 모루신(morusin), 구와논 지(kuwanon G) 및 상백피(Mori Cortex Radicis) 추출물로 이루어진 군에서 선택된 하나 이상을 유효성분으로 포함하는 근육 질환 예방 및 치료용 또는 근 기능 개선용 조성물에 관한 것이다. 본 발명에 따른 상백피 추출물, 모루신, 또는 구와논 지는 근 단백질 합성에 관여하는 p-mTOR의 단백질 발현 증가, 근 단백질 분해에 관여하는 MuRF-1과 atrogin-1의 mRNA 발현 억제, 근육 분화에 관여하는 MyoD와 myogenin의 mRNA 발현을 증가시킴에 따라, 근 기능을 탁월하게 증강하는 효과가 있다. 또한, 본 발명은 천연물이므로 부작용 없이 안전하게 사용될 수 있어, 의약품, 식품 또는 화장품으로 사용될 수 있다.

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Номер записи: 74
14-12-2017 дата публикации

시게스벡키아 오리엔탈리스 추출물을 포함하는 항비만용 조성물

Номер: KR0101809143B1
Автор: 황재관, 김미보, 김태윤
Принадлежит: (주)앗코스텍

... 본 발명은 시게스벡키아 오리엔탈리스(Siegesbeckia orientalis L.) 추출물을 유효성분으로 포함하는 비만 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명에 따른 이의 분획물은 지방세포 내에서 지방세포 분화에 관여하는 주요 전사인자(PPARγ, C/EBPα, 및 SREBP-1c)의 발현을 감소시킴에 따라, 비만에 우수한 효과가 있다. 또한, 본 발명은 천연물이므로 부작용 없이 안전하게 사용될 수 있어, 의약품 또는 식품으로 사용될 수 있다.

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Номер записи: 75
07-09-2016 дата публикации

키레놀 또는 시게스벡키아 오리엔탈리스 추출물을 포함하는 항비만용 조성물

Номер: KR0101654977B1
Автор: 황재관, 김미보, 김태윤
Принадлежит: 연세대학교 산학협력단

... 본 발명은 키레놀(kirenol) 또는 이를 함유하는 시게스벡키아 오리엔탈리스(Siegesbeckia orientalis L.) 추출물을 유효성분으로 포함하는 비만 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명에 따른 키레놀(kirenol), 또는 이를 함유하는 시게스벡키아 오리엔탈리스 추출물 또는 이의 분획물은 지방세포 내에서 지방세포 분화에 관여하는 주요 전사인자(PPARγ, C/EBPα, 및 SREBP-1c)의 발현을 감소시킴에 따라, 비만에 우수한 효과가 있다. 또한, 본 발명은 천연물이므로 부작용 없이 안전하게 사용될 수 있어, 의약품 또는 식품으로 사용될 수 있다.

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Номер записи: 76
15-12-2017 дата публикации

키레놀 또는 희첨 추출물을 포함하는 골다공증 예방, 개선 또는 치료용 조성물

Номер: KR0101809151B1
Автор: 황재관, 김미보, 송영우
Принадлежит: (주)앗코스텍

... 본 발명은 키레놀(kirenol) 또는 이를 함유하는 시게스벡키아 오리엔탈리스(Hui Chum, Siegesbeckia spp.) 추출물을 유효성분으로 포함하는 골다공증 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명에 따른 키레놀(kirenol), 또는 이를 함유하는 희첨 추출물 또는 이의 분획물은 조골세포 분화를 촉진하고, 파골세포 생성을 억제함에 따라, 골다공증 예방, 개선 또는 치료에 우수한 효과가 있다. 또한, 본 발명은 천연물이므로 부작용 없이 안전하게 사용될 수 있어, 의약품 또는 식품으로 사용될 수 있다.

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Номер записи: 77
26-07-2012 дата публикации

NOVEL USE OF FLAVONE-BASED COMPOUND

Номер: WO2012099449A2
Автор: HWANG, Jae-Kwan, KIM, Jaekyung
Принадлежит:

The present invention relates to a novel use of a flavone-based compound or Kaempferia parviflora extract, and more particularly, to a composition for anti-wrinkle, anti-aging and improvement of skin elasticity, comprising a flavone-based compound or Kaempferia parviflora extract, as an active ingredient. The composition of the present invention has superior effects of inhibiting collagenases and promoting collagen production, and therefore, may be effective in preventing skin wrinkles and aging and improving skin elasticity, and has superior effects of inhibiting loss of skin moisture and thus is effective in skin moisturizing.

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Номер записи: 78
20-02-2018 дата публикации

스쿠알렌을 함유하는 근기능 향상 및 근육 손상 예방용 조성물

Номер: KR0101830395B1
Автор: 황재관, 이세인, 김미보, 김창희
Принадлежит: (주)앗코스텍

... 본 발명은 스쿠알렌을 함유하는 근육 질환 예방, 치료, 개선 또는 손상 근육 재생용 조성물에 관한 것으로, 보다 상세하게는 본 발명의 스쿠알렌은 근육 세포에서 근단백질 합성 및 근육량 증가와 관련된 단백질의 발현을 증가시키며, 근 단백질 분해에 관여하는 효소의 발현을 mRNA 수준에서 억제하고, 손상 근육의 회복을 빠르게 회복시키는 효과가 있다. 또한, 본 발명은 천연물이므로 부작용 없이 안전하게 사용될 수 있어, 의약품, 식품 또는 화장품으로 사용될 수 있다.

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Номер записи: 79
14-12-2017 дата публикации

퓨코스테롤을 포함하는 근육 질환 예방, 개선 또는 치료용 또는 근 기능 개선용 조성물

Номер: KR0101809156B1
Автор: 황재관, 김미보, 김창희
Принадлежит: (주)앗코스텍

... 본 발명은 퓨코스테롤(fucosterol), 모자반, 모자반 분쇄물, 모자반 추출물, 톳, 톳 분쇄물 또는 톳 추출물을 포함하는 근육 질환 예방 또는 치료용 또는 근 기능 개선용 조성물에 관한 것이다. 본 발명에 따른 퓨코스테롤, 모자반, 모자반 분쇄물, 모자반 추출물, 톳, 톳 분쇄물 또는 톳 추출물은 근 단백질 합성에 관여하는 주요 유전자 p-mTOR의 단백질 발현 증가, 근 단백질 분해에 관여하는 MuRF-1과 atrogin-1의 mRNA 발현 억제, 근육 분화에 관여하는 MyoD와 myogenin의 mRNA 발현을 증가시킴에 따라, 근 기능을 탁월하게 증강하는 효과가 있다. 또한, 본 발명의 조성물은 천연물이므로 부작용 없이 안전하게 사용될 수 있어, 의약품, 식품, 화장품 또는 가축 사료 또는 사료첨가제 등으로 사용될 수 있다.

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Номер записи: 80
10-01-2018 дата публикации

COMPOSITION FOR RELIEVING HANGOVER COMPRISING EXTRACT OF CURCUMA XANTHORRHIZA ROXB.

Номер: KR1020180003992A
Автор: KWON, JIN HYOUK, YOON, MANN SEOK, LEE, JIN WOO, SHIM, JAE SEOK, PARK, YOUNG MIN, HWANG, JAE KWAN, PARK, JIN WOO, CHOI, SU YOUNG
Принадлежит:

The present invention relates to a composition for relieving hangover, which increases activity of an alcohol dehydrogenase and reduces the concentration of alcohol in the blood and acetaldehyde by comprising an extract of Curcuma xanthorrhiza Roxb., thereby being effective in for relieving hangover. COPYRIGHT KIPO 2018 (AA) Curcuma xanthorrhiza Roxb. (BB) Hot water extract 10 ppm (CC) Alcohol extract 10 ppm (DD) Supercritical extract 10 ppm (EE) Xanthorrhizol 10 μM (FF) Curcuma longa extract 10 ppm (GG) EtOH + Hot water extract 10 ppm of Curcuma xanthorrhiza Roxb. (HH) EtOH + Alcohol extract 10 ppm of Curcuma xanthorrhiza Roxb. (II) EtOH + Supercritical extract 10 ppm of Curcuma xanthorrhiza Roxb. (JJ) EtOH + Xanthorrhizol 10 μM (KK) EtOH + Curcuma longa extract 10 ppm ...

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Номер записи: 81
15-04-2010 дата публикации

NOVEL USE OF PANDURATIN DERIVATIVE OR BOESENBERGIA PANDURATA EXTRACT

Номер: WO2010041908A3
Автор: HWANG, Jae-Kwan, KIM, Do Un
Принадлежит:

The present invention relates to a novel use of panduratin derivative or Boesenbergia pandurata extract. More specifically, the present invention relates to: a composition containing panduratin derivative or Boesenbergia pandurata extract denoted by chemical formulas 1 to 3 as an active ingredient for preventing and treating/relieving metabolic disease; a method for treating metabolic disease characterized by administering effective amount of panduratin derivative or Boesenbergia pandurata extract to a needed individual; a use of the panduratin derivative or Boesenbergia pandurata extract to manufacture a formulation for preventing and treating/relieving metabolic diseases. The metabolic disease is selected from the group consisting of obesity, hyperlipidemia, hypercholesterolemia, and diabetes. The present invention provides a novel use of the panduratin derivative or Boesenbergia pandurata extract. The panduratin derivative or Boesenbergia pandurata extract of the present invention has ...

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Номер записи: 82
04-12-2017 дата публикации

COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING MUSCULAR DISORDERS, OR IMPROVING MUSCULAR FUNCTIONS

Номер: KR1020170132705A
Автор: HWANG JAE KWAN, KIM CHANG HEE, KIM MI BO
Принадлежит:

The present invention relates to a composition for preventing or treating muscular disorders, or improving muscular functions, which comprises fucosterol, Sargassum fulvellum, Sargassum fulvellum crushed material, Sargassum fulvellum extract, Sargassum fusiforme, Sargassum fusiforme crushed material, or Sargassum fusiforme extract. Specifically, fucosterol, Sargassum fulvellum, Sargassum fulvellum crushed material, Sargassum fulvellum extract, Sargassum fusiforme, Sargassum fusiforme crushed material, or Sargassum fusiforme extract according to the present invention has the effect of dramatically enhancing muscular functions by increasing the protein expression of p-mTOR, which is a major gene involved in muscle protein synthesis; suppressing the mRNA expression of MuRF-1 and atrogin-1 involved in muscle protein breakdown; and increasing the mRNA expression of MyoD and myogenin involved in muscle cell differentiation. Additionally, the composition of the present invention is a natural substance ...

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Номер записи: 83
06-12-2012 дата публикации

COMPOSITION FOR TREATING OBESITY AND DIABETES AND FOR INCREASING MUSCLE MASS AND IMPROVING CAPACITY FOR EXERCISE, COMPRISING EXTRACTS OF PIPER RETROFRACTUM VAHL. FRUITS AS ACTIVE INGREDIENTS

Номер: WO2012165888A2
Автор: KIM, Kyung-Jin, KIM, Min-Sun, HWANG, Jae-Kwan
Принадлежит:

The present invention relates to a food composition, and to a pharmaceutical composition, which exhibit anti-obesity effects by means of a thermogenesis produced by an activity of a UCP of fat cells, which exhibit anti-diabetes effects by means of an improved insulin resistance, increase muscle mass, and improve capacity for exercise. More particularly, the present invention relates to a novel use of a composition containing extracts of piper retrofractum, and to the food composition or pharmaceutical composition which exhibit anti-obesity effects by means of decreased body weight and body fat, exhibit anti-diabetes effects by means of ameliorated insulin resistance through the reduction of blood glucose and blood insulin, increase muscle mass by increasing an energy source being supplied to the muscles, and improve the capacity for exercise including increased endurance.

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Номер записи: 84
09-05-2018 дата публикации

희첨 추출물을 포함하는 운동수행능력 증강용 조성물

Номер: KR0101855962B1
Автор: 황재관, 김미보, 김창희
Принадлежит: (주)앗코스텍

... 본 발명은 키레놀(kirenol) 또는 이를 함유하는 희첨(Hui Chum, Siegesbeckia spp.) 추출물을 유효성분으로 포함하는 운동수행능력 증강용, 특히 지구력 향상용 조성물에 관한 것이다. 본 발명에 따른 키레놀(kirenol), 또는 이를 함유하는 희첨 추출물 또는 이의 분획물은 운동수행능력, 특히 지구력 항샹에 관여하는 주요 유전자의 단백질 발현을 증가시킴에 따라, 운동수행능력을 탁월하게 증강하는 효과가 있다. 또한, 본 발명은 천연물이므로 부작용 없이 안전하게 사용될 수 있어, 의약품 또는 식품으로 사용될 수 있다.

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Номер записи: 85
02-05-2017 дата публикации

WHOLE-GRAIN POWDER AND PRODUCTION METHOD THEREOF

Номер: KR101732125B1
Автор: HWANG, JAE KWAN, LEE, SE IN, KIM, CHANG HEE
Принадлежит: MOTHERLOVE CO., LTD., INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

The present invention relates to a whole-grain powder composition for improving or preventing weight gain, comprising whole grains in an amount of greater than 51% by weight of a whole-grain powder composition, and a production method thereof, wherein the whole-grain powder composition for improving or preventing weight gain can be used in foods for improving or preventing weight gain using whole grains which are harvested. COPYRIGHT KIPO 2017 (AA) Weight (g) (BB) Feeding period (Weeks) of an experimental diet (CC) Control group fed with normal diet (DD) Control group fed with high-fat diet (EE) High-fat diet + Powder (Weight control improvement effect test group) ...

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Номер записи: 86
20-11-2015 дата публикации

ANTI-OBESITY AND ANTI-DIABETIC COMPOSITION CONTAINING FINGERROOT POLYSACCHARIDES AS ACTIVE INGREDIENT

Номер: KR1020150129344A
Автор: HWANG, JAE KWAN
Принадлежит:

The present invention relates to an anti-obesity and anti-diabetic composition, and more specifically, to a novel use of a composition containing fingerroot polysachharides. The fingerroot polysaccharides reduce weight and body fat and significantly lower glucose and insulin concentration in blood. Therefore, provided is a food composition or a pharmaceutical composition with anti-obesity and anti-diabetic activities. COPYRIGHT KIPO 2016 (AA) Weight (g) (BB) High fat diet(HFD) (CC) High fat diet(HFD) + Polysaccharide complex(FPC) ...

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Номер записи: 87