COMPOSITION FOR IMPROVING MOTOR ABILITY OR MYOFUNCTION CONTAINING ADZUKI BEANS
The present invention refers to health beverage with red bean extract, health beverage with red bean proteins and health beverage with red bean derived peptide as an active ingredient a composition for improving performance a near function improving or motion are disclosed. (Muscle atrophy) RM proximal axis generated by muscle which gradually reduced, age regression (Cell, 119 (7): 907 - 910, 2004) and has the outside of the muscle. Proximal shaft inactive, and movement is promoted by oxidative stress or chronic inflammatory muscle function (Clinical Nutrition, 26 (5): 524 - 534, 2007) that attenuate the ability S.. The associated, muscle is the most important element which defines muscle function, muscle protein synthesis and degradation of a device is being maintained on the hinge. Protein degradation is synthesized than proximal axis symptoms occurs (The International Journal of Biochemistry and Cell Biology, 37 (10): 1985 - 1996, 2005) until. Muscle size (anabolism) (catabolism) muscle occurring in the anabolic agent that promotes or inducing an intracellular signal transduction (signaling pathways) and decomposition of muscle protein synthesis than controlled by inducing increased muscle protein synthesis to occur much signal transfer reaction, this increased muscle protein muscle area (hypertrophy, muscle swelling) or increasing the number (hyperplasia) according to fiber (The Korea Journal of Sports Science, 20 (3): 1551 - 1561, 2011) as shown by the other. (PI3K)/Akt pathway in which magnetic poles of phosphatidylinositol-a 3 kinase in a cell derived factors are near muscle swelling downstream protein (downstream proteins) murec2 protein synthesis by inducing substrate. One of the PI3K/Akt activity of various mammalian target of rapamycin (mTOR) by transmission signal to methods for incorporating some growth signal etc. have been major growth signal transduction. Activation of the two downstream target mTOR (downstream targets) in 4E a-binding protein (4EBP 1) and phosphorylated 70 provided kDa ribosomal S6 kinase by inducing muscle protein synthesis (p70S 6K) by activating an near can contribute to an increase of (The Korea Journal of Sports Science, 20 (3): 1551 - 1561, 2011; The International Journal of Biochemistry and Cell Biology, 43 (9): 1267 - 1276, 2011). With a reduced size, in the forhead box transcription factor (transcription factor) (FoxO) is involved in the ubiquitin E3 has also the advantage to move into the nuclear cytoplasmic protein degradation number factor (atrogin provided 1) enhance expression of art disapproved -1 (Disease Models & Mechanisms, 6:25 - 39, 2013) and MuRF provided 1. These expression dose intramuscular is promoted to thereby promote when increasing its safety are to be coated. The promoting activity of mTOR and increasing the amount of muscle protein expression is atrogin provided 1 and MuRF-a 1 billion number is equal to increase muscle. In addition, differentiation of muscle cells muscle formation can be controlled by various muscle modulators (muscle regulatory factors). One of these surfaces, myogenin MyoD is through the induction process where the myoblasts (myoblast) is stiffer and cells (myotube) to 0. The process formed over a bundled fiber forming angularly finally muscles is equal to (Cellular and Molecular Life Sciences, 70:4117 - 4130, 2013). One of health beverage with red bean representative metal gluconate ( , the present invention derived from plant extracts victims of the proximal shaft associated with the treatment of diseases such as insects and result number degradation muscle effort, health beverage with red bean extract of beans in muscle cells increase the level associated with an increase muscle protein synthesis and muscle protein expression in plants and can be phosphorylation, bean or health beverage with red bean extract of the present invention are uses for prevention and treatment of diseases, or near-confirm active ingredient composition for improved functionality can be used by, the present invention the arrears of work. The improving ability while exercising the present invention parties can provide near function improving or natural products that can be applied safely activity search results, improving ability to confirm the present invention active while exercising or function improving primitives health beverage with red bean the arrears of work. Thus, the purpose of the invention is health beverage with red bean ( Of the present invention another object is to provide, health beverage with red bean proteins or peptide for including active ingredient, or a composition for improving performance number [...] muscle disorders are disclosed. Of the present invention another object is to provide, health beverage with red bean extract including, a drug for improving composition [...] number are disclosed. Of the present invention another object is to provide, health beverage with red bean proteins or peptide active ingredient including, a drug for improving composition [...] number are disclosed. Said number and as a means for solving the above, the present invention refers to health beverage with red bean ( In addition, the present invention refers to health beverage with red bean proteins or peptide for including active ingredient, or a pharmaceutical composition for improving muscle diseases performance number [...] substrate. Said another number and as a means for solving the above, the present invention refers to health beverage with red bean ( In addition, the present invention refers to health beverage with red bean proteins or peptide active ingredient including, a drug for improving composition number [...] substrate. The present invention refers to the bean extract, health beverage with red bean proteins or health beverage with red bean derived peptide active ingredient including, for prevention and treatment of muscle diseases, near function improving for, or a composition for improving performance number [...] substrate. Bean extract muscle function in muscle cells of the present invention, mRNA transcription factors involved in the differentiation of muscle control or muscle cells to promote protein activity levels and muscle function or exercising and near the current channel to enhance, deterioration of performance caused by various diseases dyskinesia, muscle hypofunction, prevention of muscle loss, treatment or amelioration effect can exhibit. In addition, health beverage with red bean extract of the present invention, the peptide has a natural products derived from water into the body as pharmaceuticals or foods and health beverage with red bean-bean proteins side effects can be used effectively. In Figure 1 L6 muscle cells, health beverage with red bean processing according to mTOR measured beverage exhibits high activity of 2001 KIPO. In Figure 2 L6 muscle cells, health beverage with red bean protein expression on beverage exhibits high processing according to mRNA translation related biomarkers p provided p70S 6K p provided 4EBP 1 measured 2001 KIPO. In Figure 3 L6 muscle cells, health beverage with red bean protein degradation promoting beverage exhibits high mRNA expression of biomarkers MuRF-a 1 and atrogin provided 1 processing according to near measured 2001 KIPO. In Figure 4 L6 muscle cells, muscle differentiation of biomarkers on mRNA expression of MyoD myogenin beverage exhibits high health beverage with red bean processing according to measured 2001 KIPO. In Figure 5 L6 muscle cells, health beverage with red bean extract processing according to mTOR measured the activity of 2001 KIPO. In Figure 6 L6 muscle cells, measured the level of expression of a subcritical health beverage with red bean extract processing according to mTOR 2001 KIPO. In Figure 7 L6 muscle cells, health beverage with red bean protein and measured the level of expression of an enzymatic reaction by health beverage with red bean peptide processing according to mTOR 2001 KIPO. In Figure 8 L6 muscle cells, health beverage with red bean peptide processing according to mRNA translation related biomarkers measured on protein expression p provided p70S 6K p provided 4EBP 1 2001 KIPO. In Figure 9 L6 muscle cells, muscle differentiation of biomarkers on mRNA expression of MyoD myoenin bean peptide processing according to measured 2001 KIPO. In Figure 10 L6 muscle cells, beverage exhibits high activity of sword red bean processing according to mTOR measured 2001 KIPO Figure 11 COS provided 7 in kidney cells, health beverage with red bean beverage exhibits high processing according to PGC-a 1 α activity measured 2001 KIPO. In Figure 12 L6 muscle cells, health beverage with red bean processing according to beverage exhibits high mitochondrial biosynthesis of biomarkers PGC-a 1 alpha, ERR α, NRF provided 1, 2001 KIPO measured Tfam of mRNA expression. In Figure 13 L6 muscle cells, health beverage with red bean protein and enzyme reaction by health beverage with red bean peptide processing according to PGC-a 1 α activity measured 2001 KIPO. In Figure 14 L6 muscle cells, health beverage with red bean peptide processing according to mitochondrial biosynthesis of biomarkers PGC-a 1 alpha, ERR α, NRF provided 1, 2001 KIPO measured Tfam of mRNA expression. Figure 15 COS provided 7 in kidney cells, sword red bean beverage exhibits high processing according to PGC-a 1 α activity measured 2001 KIPO. Figure 16 shows a proximal shaft oil also in RAT, health beverage with red bean processing according to a beverage exhibits high strength measured 2001 KIPO. Figure 17 shows a proximal shaft oil also in RAT, health beverage with red bean processing according to a beverage exhibits high mangostin measured 2001 KIPO (a: exercise, b: movement distance). Figure 18 shows a proximal shaft oil also in RAT, health beverage with red bean weight measured beverage exhibits high processing according to foreground the muscle which boils 2001 KIPO. Hereinafter, the constitution of the invention specifically described as follows. The present invention refers to health beverage with red bean ( In the specification ' health beverage with red bean ( In the specification 'health beverage with red bean extract' big extract obtained by extracting the health beverage with red bean. Health beverage with red bean extract water from the health beverage with red bean manufacturing method, C1 To C6 Organic solvents, one or more solvent selected from the group consisting a subcritical fluid and supercritical fluid can be obtained by extracting health beverage with red bean. More specifically, 1 to 6 carbon atoms said solvent is alcohol (alcohol), acetone (acetone), ether (ether), benzene (benzene), chloroform (chloroform), ethyl acetate (ethyl acetate), methylene chloride (methylene chloride), hexane (hexane), cyclohexane (cyclohexane) and petroleum ether (petroleum ether) can be one or more selected from the group consisting of. More specifically, including manufacturing method to extract said steps of preferably but not limited to crude number by: 1) Health beverage with red bean applied to extraction solvent extracting; 2) Step 1) extract of filtering step; and 3) Step 2) filtering cream extract after drying. In said method, step 1) the number of health beverage with red bean or the like can be used without a medical products commercially available. In said method, health beverage with red bean extract extraction method include filtration, heat extraction, immersion extraction, reflux cooling extraction, ultrasound extraction, using a conventional method such as a ultra-high pressure extraction and a subcritical extraction can be the party industry. In relation to the extraction method, said extracting device to extract 100 to 500 mpa when ultra-high pressure mercury pressure preferably. In said method, step 3) the decompression of enrichment is limited using vacuum decompression thickener or vacuum rotary Eq preferably does not. In addition, drying reduced pressure drying, vacuum drying, boiling drying, preferably spray-dried or lyophilized does not limited. In addition, the present invention refers to health beverage with red bean proteins or peptide for including active ingredient, or a pharmaceutical composition for improving muscle diseases performance number [...] substrate. In the specification, ' health beverage with red bean proteins' is a i) to v) can be obtained by a method comprising the steps of: I) extracting comminuted dried health beverage with red bean cyclohexane solvent; Ii) said step i) extracted from the hexane extract number and a stand-alone, foil to pH 7 by adding water. 0 To 10. 0 Conditions the steps of; Iii) said step ii) left in solution to yield a supernatant by centrifuging; Iv) said step iii) obtained supernatant again in pH 2. 0 To 6. 0 Conditions steps; and V) said step iv) centrifuging a health beverage with red bean left in solution precipitation precipitation derived protein yield. In the specification, 'health beverage with red bean derived peptide' is isolated from health beverage with red bean-bean protein by degrading enzymes is obtained by treating meaning that the other. Specifically, health beverage with red bean derived peptides to i) to vii) can be obtained by a method comprising the steps of: I) extracting comminuted dried health beverage with red bean cyclohexane solvent; Ii) said step i) extracted from the hexane extract number and a stand-alone, foil to pH 7 by adding water. 0 To 10. 0 Conditions the steps of; Iii) said step ii) left in solution to yield a supernatant by centrifuging; Iv) said step iii) obtained supernatant again in pH 2. 0 To 6. 0 Conditions the steps of; V) said step iv) left in solution to yield a health beverage with red bean proteins centrifuging precipitation precipitation; Vi) said step v) obtained health beverage with red bean proteins without further after enzyme hydrolysis in an enzymatic reaction, filtration of the precipitate industry association step number; and Vii) said step vi) number obtain filtrate for reparing over freezing and drying the precipitate in peptides. In the specification, said 'hydrolase' is the number [...] (Alcalase), focus by step [lu person (Flavourzyme), the number (Neutrase) as new [thu, pro other [...] (Protamex) and protein hydrolase - NP selected from the group consisting of one or more protein hydrolysates (Protease-a NP) may be enzymes disclosed. The specification in muscle disease is a muscle hypofunction, muscle wasting due to a muscle disease or degeneration of these reported nitrile preferably. Muscle wasting or degradation said genetic factor, factor for treating dermatological, aging and the like caused, muscle consumption gradually muscle loss, muscle, skeletal muscle or cardiac muscle and characterized in particular outside of the voluntary muscle and degeneration. Examples of treating diseases associated tension decay (atony), proximal [...] (muscular atrophy), muscle nutrition symptoms (muscular dystrophy), degeneration, myasthenia, cachexia (cachexia) (sarcopenia) 19 and the like is cited. Muscle bottom where the composition of the present invention, muscle is not relayed type number. In the specification, the 'near' tendon, muscle, and generic gun referred, " or 'near function of muscle function' means the ability to force by the shrinkage of the eye muscles can be produced and, in order to supply a contractive force compressing the muscle resistance strength can be; muscle contraction and relaxation can be given weight how long or how many times repeatedly indicating whether a near endurance ability; and in a short time by means of a bare foot to exert a strong force capability. The proportional function is near said muscle, terms' near function improving ' can provide near the function enhancing big positive direction. In the specification, 'exercising' daily living or whether it is possible to run the operation body appearance in sports, for excellent, target, such as when swimming is detected, the power feed to the, strongly, accurately, old, can be wrought that represents an extent, while exercising the muscular strength, mangostin agility of factor defined as substrate. Terms' improving ability while exercising ' movements crack or enhancing a preset substrate. Pharmaceutical compositions of the present invention composition for improving when exercising, recuperation of prevention or treatment of diseases caused capacity can be used. Examples of degenerative disease is a disease associated with, disease, lowering endurance use, lowering a bare foot use, use enervation, like muscle waste and depression is cited. The potentiating effect where the composition of the present invention while exercising, not relayed in the form of number and types of movement. Pharmaceutical compositions of the present invention near function when, muscle wasting or degradation due to prevention or treatment of muscle diseases can be used. Muscle consumption and degradation genetic factor, factor for treating dermatological, aging and the like caused, muscle consumption gradually muscle loss, muscle, skeletal muscle or cardiac muscle and characterized in particular outside of the voluntary muscle and degeneration. Examples of treating diseases associated tension decay (atony), proximal [...] (muscular atrophy), muscle nutrition symptoms (muscular dystrophy), degeneration, myasthenia, cachexia (cachexia) (sarcopenia) 19 and the like is cited. Muscle bottom where the composition of the present invention, muscle is not relayed type number. Pharmaceutical compositions of the present invention for improving when exercising, prevention or treatment of diseases caused degradation capacity can be used. Examples of diseases associated disease, lowering endurance use, lowering a bare foot use, use enervation, like muscle waste and depression is cited. The potentiating effect where the composition of the present invention while exercising, not relayed in the form of number and types of movement. Pharmaceutical compositions unexpectedly give rise further comprises pharmaceutically acceptable carrier of the present invention can be. Pharmaceutically acceptable carrier include for example, for parenteral administration can be further includes a carrier or carrier for oral administration. For oral administration carrier lactose, starch, a cellulose derivative, magnesium stearate, stearic acid and the like can be. In addition water carrier for parenteral administration, suitable oil, saline, aqueous glucose and a glycol and the like can be. In addition, stabilizing number and preservation can be further includes a number. Suitable stabilizing number include hydrogen sulfite with sodium sulfate, antioxidant such as ascorbic acid or sodium sulfide in number flow tides. Suitable shelf number include benzalkonium chloride, methyl or propyl paraben - the pin is preparation of butanol. Other pharmaceutically acceptable carrier include the following the nucleotide can be described with reference to the (Remington's Pharmaceutical Sciences, 19th ed. , Mack Publishing Company, Easton, PA, 1995). Any method of the present invention can be a mammal including administering pharmaceutical compositions unexpectedly give rise even. E.g., oral or parenteral administration can be, but not limited to parenteral administration method include the number is one, intravenous, intramuscular, in artery, intramedullary, in epidural, intracardiac, transdermal, subcutaneous, intraperitoneally, intranasally, Minister, topical, in a menopausal or be a sublingual or rectal. Such administration provides path described above of the present invention pharmaceutical compositions can be used for oral administration or for parenteral administration can number number number according to elder brother anger. One or more buffer number (e.g., saline or PBS) number when elder brother anger, antioxidant number, bacteriostatic number, chelating number (e.g., EDTA or glutathione), filling number, a specific number, number coupled, adjuvants (e.g., aluminum hydroxide), suspension number, rich number wet number, number or disintegrating number surfactants, to a method for using dilution number number number or excipient can be. Positive number number number is solid for oral administration, ring number, acid number, granules number, number liquid, gel number, number syrup, slurry number, such as included in a suspension or capsule number, at least one excipient of the present invention is pharmaceutical compositions comprising such solid number number number for example, starch (corn starch, wheat starch, rice starch, potato starch or the like comprising), purification of calcium (calcium carbonate), sucrose (sucrose), lactose (lactose), dextran with [thu five [su, sorbitol, mannitol, xylitol, maltitol sweeteners, cellulose, methylcellulose, sodium carboxylic [...] and hydroxypropyl methyl - cellulose gum or gelatin pressure is lowered bath can be number. For example, active ingredients in combination with solid excipients on number crushed finely be enabled by the auxiliary number by adding a positive number or dragee number into granules mixture can be obtained. In addition to excipients such as talc [...] lubricating number are used are also simple number magnesium. For liquid oral suspension include number number number, number content, oil in water or liquid paraffin to a simple dilution number like number or syrup number corresponding number in addition to the commonly used various excipients, for example wet number, sweetener number, direction number or preserving number can be like. In addition, if desired the cross-linked polyvinyl pyrrolidone, agar, alginic acid or sodium alginate can be disintegrating the addition of like number, number clause cohesion, lubricating number, wet number, perfume, and bad number can be emulsion further includes a number or the like. Pharmaceutical compositions of the present invention parenterally administering a suitable carrier for injection with a number when parenteral, nasal inhalation in the form of transdermal administration method according to the publicly known elder brother anger number number number and sugar industry can be disclosed. In the case of scanning said number must be protected from contamination of microorganisms such as bacteria and fungi must sterilization should. Examples of suitable carrier in the case of scanning number but not limited to, water, ethanol, polyol (e.g., glycerol, propylene glycol and liquid polyethylene glycol and the like), mixtures thereof and/or plant oil including be a solvent or dispersing medium. More preferably, suitable carrier include hank [su solution, ringer's solution, phosphate buffered saline (PBS) containing a high pressure injection for sterilization be, 10% ethanol, 5% propylene glycol and 40% such as dextran with [thu [cu and appearing in the solution and the like can be used. Scanning said number from contamination microorganisms order to protect the paraben, chloro butanol, phenol, sorbitol empty mountain, it will live with the mote maul various antibacterial and antifungal number can be further includes a number. In addition, in order to produce sodium chloride such as number of scanning said number is further comprises a saccharide can be. In the case of transdermal administration number number ointment, cream number, number lotion, gel number, number external solution, pasta number, candle [...] number, such as in the form of air roll number multiple myelomas are included. In said 'transdermal administration' pharmaceutical composition is topically administered to a pharmaceutical compositions containing effective amounts of the active ingredients into the skin from being transferred to the big. In the case of inhalation number, a compound for use according to the present invention also relates to the propulsion number, for example, dichloro chlorofluoromethane, production with [phul base oro methane, dichloro tetra [phul base oro ethane, carbon dioxide or other suitable gas to, can be conveniently disposed about a pressurized pack or fogging machine from inside the aerosol spray form. In the case of a pressurized aerosol, the dosage unit can be determined by a valve number [...] deliver a metered amount. For example, inhaler or blowing compounds to be used in gelatin capsule and cartridge, and configured to contain a number of powder mixtures such as starch powder suitable for peak or lactoperoxidase elder brother anger number can be disclosed. For parenteral administration generally prepares a prescription number number may be publicly known all about chemistry it stands document (Remington's Pharmaceutical Science, 15th Edition, 1975. Mack Publishing Company, Easton, Pennsylvania 18042, Chapter 87: Blaug, Seymour) is disclosed. Pharmaceutical compositions unexpectedly give rise health beverage with red bean extract of the present invention, dimethyl-bean protein or peptide health beverage with red bean preferred when exercising a near function improving effect or effect can be [...] number. In the specification, referred to as' effective amount ' it voice controls than a response of the amount it is preferably near function more in order to improve or exercising an amount sufficient to saying the other. Pharmaceutical compositions of the present invention bean extract, health beverage with red bean proteins or peptides which facilitate health beverage with red bean 0. 01 To 99. 99% Can be included, the pharmaceutically acceptable carrier can be amplifiers are remaining. Pharmaceutical compositions of the present invention included in health beverage with red bean extract, health beverage with red bean protein or health beverage with red bean number which will like depending on width of the peptide composition amount is effective. Total amount is effective pharmaceutical composition of the present invention can be administered to patients in a single dose (single dose), multiple dose (multiple dose) administered long split treatment method can be administered to the patient by (fractionated treatment protocol). Diseases of the present invention pharmaceutical compositions unexpectedly give rise to varying degrees of effective ingredient content can be different. Parenteral administration hear said health beverage with red bean extract, health beverage with red bean per 1 kg body weight per day as a reference protein or health beverage with red bean peptide preferably 0. 01 To 50 mg, more preferably 0. 1 To 30 mg administered in an amount of to, and oral administration hear health beverage with red bean extract, health beverage with red bean per 1 kg body weight per day as a reference protein or health beverage with red bean peptide preferably 0. 01 To 100 mg, more preferably 0. 01 To 10 mg can be administered in an amount of from 1 to many times made in administration. However said health beverage with red bean extract, health beverage with red bean-bean protein or peptide pharmaceutical composition as well as routes and treatment times the capacity of the patient's age, weight, health, sex, disease severity, such as factor would be an effective dose for the patient dietary and excretion rate is determined not use, this having the health beverage with red bean extract NaOCl when considered was found conventional knowledge, health beverage with red bean-bean protein or peptide or a use according to specific enhance the performance function near suitable effective dose may be determining are disclosed. Effect of the invention the present invention according to pharmaceutical compositions thereof may also exhibits a number type, particularly one method and administration routes of non number without substrate. Of the present invention pharmaceutical compositions can be used alone, or surgical, radiation therapy, hormone therapy, chemotherapeutic or biological reactions using method and can be used in combination with control number. In addition health beverage with red bean extract of the present invention pharmaceutical compositions unexpectedly give rise, health beverage with red bean protein or peptide including number-number number of active ingredient can be [...] external health beverage with red bean. Number skin preparation for external use of the present invention pharmaceutical compositions when used, further fatty substance, organic solvent, dissolved number, number and gelling number concentrated, softening number, antioxidant number, number of suspension, stabilizing number, foam (foaming agent) number, direction number, number surfactants, water, ion emulsion number, nonionic emulsion number, charging number, sequestering number, chelating number, preserving number, vitamin, blocking number, number presented, essential oil, dye, pigment, hydrophilic active number, size of less lipophilic active number or any other number skin preparation for external use such as composition based on lipid vesicles or components such as normally used in dermatological field containing auxiliary number can be. In addition said components are typically used in dermatological field amount can be introduced. Medicinal compositions of the present invention to skin when excited ball number number, the number is one but not limited to, ointment, patch, gel, cream or spray number such as be a type number. In addition, a drug or a food composition of the present invention for improving while exercising number [...] substrate. When food composition of the present invention near function improving food composition which, muscle hypofunction, muscle wasting due to degeneration or muscle disease can be used for preventing or ameliorating diseases reported nitrile. Muscle wasting or degradation said genetic factor, factor for treating dermatological, aging and the like caused, muscle consumption gradually muscle loss, muscle, skeletal muscle or cardiac muscle and characterized in particular outside of the voluntary muscle and degeneration. Examples of treating diseases associated tension decay (atony), proximal [...] (muscular atrophy), muscle nutrition symptoms (muscular dystrophy), degeneration, myasthenia, cachexia (cachexia) (sarcopenia) 19 and the like is cited. Muscle bottom where the composition of the present invention, muscle is not relayed type number. The proportional function is near said muscle, terms' near function improving ' can provide near the function enhancing big positive direction. Food composition of the present invention for improving food composition which when exercising, recuperation of prevention or treatment of diseases caused capacity can be used. Examples of degenerative disease is a disease associated with, disease, lowering endurance use, lowering a bare foot use, use enervation, like muscle waste and depression is cited. The potentiating effect where the composition of the present invention while exercising, not relayed in the form of number and types of movement. (Functional food) of the present invention food composition is a functional food, nutritional supplement (nutritional supplement) number, health food (health food), food additives (food additives) and feed such as number of all types which, in taste human or livestock animals including toward the substrate. Said type of food composition according to publicly known method per industry normally a high pressure liquid coolant number can be in various forms. Said type of food composition according a method number normally publicly known contrast in various forms can be high pressure liquid coolant. It general food beverage (including alcoholic beverages) but not limited to, fruit and processed food (e.g.: fruitcanning, bottling, jam, such as e oh male id), fish, meat and processed food (e.g.: ham, sausage like cone vee [phu), (example: kneaded, buckwheat noodles, if, spine gate, such as macaroni) gain product noodles, juice, various drink, cookie, taffy, oil number article (example: butter, such as [...]), maintaining an edible plant, 80 wt, vegetable protein, retort food, frozen food, various seasoning (example: soybean paste, soy sauce, such as source) or the like can be added to said health beverage with red bean extract and health beverage with red bean peptide number high pressure liquid coolant. In addition, this deposition number nutritional supplement capsule but not limited to, tablet, ring or the like health beverage with red bean extract, health beverage with red bean-bean protein or peptide number can be added to high pressure liquid coolant. In addition, health food include but not limited to for example, said health beverage with red bean extract itself difference, high pressure liquid coolant in the form of a drinkable juice and number to the drinking (health drink) pasteurization, granulation, encapsulation and powder or can be taken. In addition, said health beverage with red bean extract, health beverage with red bean-bean protein or peptide used in form of a powder or concentrate a food additives number order number can be used to form high pressure liquid coolant. In addition, said health beverage with red bean extract, health beverage with red bean-bean protein or peptide known publicly known active ingredient when it is judged that the potentiating effect near function improving or kinetic performance number in the form of the composition can be mixed together with high pressure liquid coolant. Health beverage composition for improving composition of the present invention near function improving or kinetic performance when used, said health drink compositions contain conventional beverage is lower number or natural carbohydrate containing additional ingredients can be like flavor. The above-described natural carbohydrate glucose, oligosaccharides such as mono pathogenic agent; liver, such as shoe cross and d company kara id; dextrin, cyclodextrin such as polysaccharide; xylitol, sorbitol, such as processes for the preparation of [...][...] be. The sweetener number TAU denaturing detergent, such as Stevia extract natural sweetener number; saccharin, oh [su group [lu with burning, can be use such as synthetic sweetener number. The ratio of said natural carbohydrate of the present invention per 100 ml composition generally about 0. 01 - 0. 04 G, preferably about 0. 02 - 0. 03 G are disclosed. Health beverage with red bean extract, health beverage with red bean protein or peptide or a food composition for improving performance bean is near function can be effective ingredient, achieve a performance quantity near function improving or motion action for improving effective amount of a specifically defined but not limited to, 0 relative to the weight of the total of the overall composition. 01 To 100% by weight preferably disclosed. Food composition of the present invention is a composition for improving performance bean extract with near function improving or motion which is known to have other active ingredient are mixed together to number bath 1308. In addition to the health food of the present invention said various nutritional number, vitamin, electrolyte, flavor number, colored number, [pheyk the [thu it buys, [pheyk the [thu it buys salt, alginic acid, alginate salts, organic acid, protective colloidal thickening number, pH control number, stabilizing number, antiseptic number, glycerin, number of calcium hydroxide can be alcohol or the like. In addition to health food of the present invention natural fruit juice, fruit juice beverage, or vegetable beverage containing pulp can be number for numerical control machine. These components can be used independently or mixing. The triazines of the present invention composition 100 parts by weight ratio of added significant but not large number 0. 01 - 0. 1 Parts by weight of generally is selected from the range are disclosed. Hereinafter the present invention in the embodiment a, and positive examples attainments experiment number through the corresponding business are provided as follows. Stage, to in the embodiment, the present invention is exemplified ephemeral attainments and positive examples experiment a number, in the embodiment of the present invention to content, not the limited to experiment number attainments and positive examples. [In the embodiment 1] Health beverage with red bean extract number bath <1-1> Health beverage with red bean crude methanol extract number Dried bean ( <1-2> Health beverage with red bean extract of cervi number bath Dried bean ( <1-3> Number of health beverage with red bean crude ethyl acetate extract Dried bean ( <1-4> Of health beverage with red bean Hexane Extract number bath Dried bean ( <1-5> Of health beverage with red bean Heat Extract number bath Dried bean ( <1-6> Ultra-high pressure mercury health beverage with red bean extract number bath Dried bean ( <1-7> health beverage with red bean A subcritical Extract number bath Dried bean ( [In the embodiment 2] Health beverage with red bean proteins and Peptides Separation <2-1> Health beverage with red bean separation of proteins Dried bean ( <2-2> The number [...](Alcalase) Processing according to health beverage with red bean Peptide Number bath In the embodiment <2-1>Obtained in 1% (Novozymes, Bagsvaerd, Denmark) and number of inactivating the protein by health beverage with red bean [...] 50 with respect to the 6 hours without further application in an enzymatic reaction. 6 After time, 20 minutes at 90 by deactivating the enzyme in a stand-alone number was found to precipitate filtered to only 2 watts. Filtered liquid freeze dryer (ilShin Lab Co. Ltd. , Seoul, Korea) by the process of water stand-alone full number [...] peptide health beverage with red bean number obtained. <2-3> By step [lu person focus(Flavourzyme) Processing according to health beverage with red bean Peptide Number bath Saidin the embodiment <2-2>An equivalent method to the [lu being, [phul step by step [lu person (Novozymes) and number [...] instead focus processing process of health beverage with red bean obtained peptide. <2-4> As new [thu number(Neutrase) Processing according to health beverage with red bean Peptide Number bath Saidin the embodiment <2-2>An equivalent method to the number instead of as new [thu new [thu [...] number processing process of health beverage with red bean peptide number (Novozymes) as obtained. <2-5> Pro other [...](Protamex) Processing according to health beverage with red bean Peptide Number bath Saidin the embodiment <2-2>An equivalent method to the number [...][...] (Novozymes) instead pro other processing process of health beverage with red bean [...] pro other peptide obtained. <2-6> Number - NP proteasome (Protease-a NP) processing according to health beverage with red bean Peptide Number bath Saidin the embodiment <2-2>An equivalent method to the number number - NP (Bioland, Asan, Korea) instead [...] comprised of processing number - NP peptide comprised of process of health beverage with red bean obtained. [In the embodiment 3] Sword red bean extract number bath <3-1> Sword red bean crude methanol extract number Dried sword red bean ( <3-2> Sword red bean extract of cervi number bath Dried sword red bean ( <3-3> Ethyl acetate extract of sword red bean number bath Dried sword red bean ( <3-4> Of sword red bean Hexane Extract number bath Dried sword red bean ( <3-5> Of sword red bean Heat Extract number bath Dried sword red bean ( <3-6> Ultra-high pressure mercury sword red bean extract number bath Dried sword red bean ( <3-7> Sword red bean A subcritical Extract number bath Dried sword red bean ( [In the embodiment 4] Sword red bean proteins and Peptides Separation <4-1> Separation of sword red bean proteins Dried sword red bean ( <4-2> The number [...](Alcalase) Processing according to sword red bean Peptide Number bath In the embodiment <4-1>Sword red bean obtained in 1% (Novozymes, Bagsvaerd, Denmark) and number of inactivating the protein by [...] 50 with respect to the 6 hours without further application in an enzymatic reaction. 6 After time, 20 minutes at 90 by deactivating the enzyme in a stand-alone number was found to precipitate filtered to only 2 watts. Filtered liquid freeze dryer (ilShin Lab Co. Ltd. , Seoul, Korea) stand-alone water by the process of peptide number full number [...] sword red bean obtained. <4-3> By step [lu person focus(Flavourzyme) Processing according to sword red bean Peptide Number bath Saidin the embodiment <4-2>An equivalent method to the [lu being, [phul step by step [lu person (Novozymes) and number [...] instead focus processing process of peptide sword red bean obtained. <4-4> As new [thu number(Neutrase) Processing according to sword red bean Peptide Number bath Saidin the embodiment <4-2>An equivalent method to the number instead of as new [thu new [thu [...] number (Novozymes) is processed by the process of peptide as sword red bean number obtained. <4-5> Pro other [...](Protamex) Processing according to sword red bean Peptide Number bath Saidin the embodiment <4-2>An equivalent method to the number [...][...] (Novozymes) instead pro other processing process of peptide pro other [...] sword red bean obtained. <4-6> Number - NP proteasome (Protease-a NP) processing according to sword red bean Peptide Number bath Saidin the embodiment <4-2>An equivalent method to the number - NP (Bioland, Chaonan, Korea) instead [...] number comprised of processing number - NP treatment with the peptide comprised of sword red bean obtained. [Experiment example 1] Health beverage with red bean ethanol extract of muscle-generating active confirmation The mTOR protein phosphorylation when activated, PI3K/Akt increased muscle protein synthesis and muscle proteins that are involved in signal transduction pathway near within cells of activation are capable of known. The, health beverage with red bean beverage exhibits high generating inducing activity of muscle in order to identify, using mTOR Sandwich ELISA kit (Cell Signaling Technology, Beverly, MA, USA) has been confirmed that the activity of mTOR. The L6 cells (ATCC; Manassas, VA, USA) muscle capillary [...][...] a right [thay 10% (FBS; Hyclone, Logan, UT, USA) Dulbecco's modified Eagle's media (DMEM; Hyclone) containing 6 - well plate with 1 × 105 In such a manner that 24 hours after inoculation cell/mL him as. Culture nor post-incubation, well 2% horse serum (HS; Hyclone) stand-alone the medium containing DMEM (Hyclone) number and replaced by culturing cells to cause differentiation of L6 cells (myotube) has been further 6 is stiffer. Then, said in the embodiment <1-2>100% Ethanol at a concentration of 40 μg/mL high pressure liquid coolant in a health beverage with red bean extract ethanol from a number 12 him as time processing cells. Culture nor post-incubation, cell lysis buffer solution (cell lysis buffer) with respect to the dissolved processing cells. In pod defect in cell lysate obtained protein (Bio-a Rad Laboratories Inc. , Hercules, CA, USA) measurement method then, quantifying the concentration 1 mg/mL with 50 μl cell lysate by anti - mTOR antibodies in 2 hours 37 °C which is included in the troublesome him as. Culture nor post-incubation, washing buffer solution is washed the total 4 times (Washing buffer), liberal in citation antibody (detection antibody) in processing when the beany 1 37, total 4 times washed the back washing buffer solution, enzyme (horseradish peroxidase, HRP) peroxide free-bonded 2 difference antibodies into and out of the bean paste in 30 minutes 37 him as. Finally washing buffer solution washed the total 4 times, 10 minutes each well TMB substrate 37 into the stop buffer solution (stop solution) by applying reaction of culturing in TBM halt. 2 Minutes behind, by measuring absorbance at a wavelength 450 nm beverage exhibits high health beverage with red bean root intracellular mTOR a location measured level. Also shown to result 1. As a result, as shown in the beverage exhibits high health beverage with red bean in L6 muscle cells also 1 by a processing of the activity of the mTOR significantly (** P < 0. 01) Increases were confirmed. This ability to increase muscle generation in muscle cells of the present invention bean extract is excellent in another substrate. [Experiment example 2] Health beverage with red bean ethanol extract Muscle protein Synthesis involved factor MRNA Identifying transcription level The L6 cells (ATCC) containing 10% FBS DMEM (Hyclone) muscle capillary [...] a 6 - well plate with 2 × 105 Cell/mL so him as after inoculation. About 80 to 85% at the time when the cell density, the DMEM medium containing 2% HS and well number (Hyclone) stand-alone to cause differentiation of L6 cells (myotube) been replaced (Hyclone) root cells. After 6, said in the embodiment <1-2>Number 25, 50 or 100% ethanol extract at a concentration of 40 μg/mL high pressure liquid coolant into ethanol in DMEM medium (Hyclone) melting a health beverage with red bean to exchanging him as 24 hours. The, sample 0 instead. 01% DMSO regulated population of processing the electrodes respectively. 24 Hours later, cells at the protein hydrolase billion number number cocktail (Sigma non-Aldrich St. Louis, MO, USA) included in the buffer solution (ELPIS provided Biotech, Daejeon, Korea) dissolve NP provided 40 cell lysate obtained. 10 Minutes at 13,000 rpm comprises centrifuging the supernatant was obtained cell lysis to take. Defect in supernatant then quantifies the pod protein concentration, concentration of the protein by SDS-a PAGE heating 5 minutes 10% SDS-a PAGE gel electrophoresis was deployed to isolate the proteins in a cell. Nitrocellulose membrane was separated proteins are transferred. Then, anti - p provided p70S 6K antibodies, anti - t provided p70S 6K antibodies, anti - p provided 4EBP 1 antibodies, each antibody (Cell Signaling Technology) - α-a tubulin-positive anti - t provided 4EBP 1 2. 5% Bovine serum albumin (BSA) to 1:1000 dilution ratio 1 to nitrocellulose membrane 20 with a protein delivery time difference antibodies was reacted at ambient temperature. 1 Difference value of 28 to antibodies, (Tris-a buffer Saline Tween 20 (TBST) 10 minutes using nitrocellulose membrane was-wash 3. Then, recognizing antibody HRP 1 difference-bonded 2 difference antibodies (Bethyl Laboratories, Inc. , Montgomery, TA, USA) 2 a. 5% BSA (bioWORLD) to 1:5000 dilution to 2 hours so that the nitrocellulose membrane has been reacted at ambient temperature, using the bell 3 times 10 TBST over his cleaning. ECL reagent (Amersham, Tokyo, Japan) using the [wey the [su it shook off [...] protein band is to color it does,, G; (Syngene, Cambridge, UK) to color using a protein band BOX EF imaging system therefrom. Also shown to result 2. As a result, as shown in Figure 2, health beverage with red bean in L6 muscle cells along treating beverage exhibits high participating in the synthesis of muscle protein mRNA transfer via p provided p70S 6K and increased levels of the protein expression were confirmed p provided 4EBP 1. This muscle protein synthesis in muscle cells of the present invention bean extract is associated factor promotes mRNA translation process means other. [Experiment example 3] Health beverage with red bean ethanol extract protein degradation billion active confirmation number near L6 cells (ATCC) containing 10% FBS DMEM (Hyclone) muscle capillary [...] (Hyclone) is a 6 - well plate with 2 × 105 Cell/mL so him as after inoculation. About 80 to 85% at the time when the cell density, the DMEM medium containing 2% HS and well number (Hyclone) stand-alone (Hyclone) to cause differentiation of L6 cells (myotube) has been exchanging stiffer and cells. 2 Replaced during differentiation the matter into the fresh media at a total 6. After differentiation, saidin the embodiment of DMEM medium containing 50 ng/mL TNF a-α <1-2>100% Ethanol at a concentration of 40 μg/mL high pressure liquid coolant in a health beverage with red bean extract ethanol from a number 20 or a seam sealing, was cells. 6 Hours, total RNA using TRIzol reagent (Takara, Osaka, Japan) was separating. Total RNA is isolated nano drop (NanoDrop 1000; Thermo Fisher Scientific Inc. , Waltham, MA, USA) using his reservoir. The are provided to 16 μl RNA, reverse transcriptase premix (Reverse Transcriptase Premix, ELPIS provided Biotech) (Gene Amp PCR System 2700; Applied Biosystems, Foster City, CA, USA) by mixing it with PCR machine using 42 °C 55 minutes, at 70 °C 15 minutes-configurated to cDNA. During 4 μl of cDNA synthesized cDNA, [table 1] to a sequence from forward and reverse primer pair (Bioneer, Deajeon, Korea), and high pressure liquid coolant mixing sample after PCR PCR premix (ELPIS provided Biotech) number, 95 °C in 30 seconds, in 1 minutes 60 °C, in conducting the operation of PCR 1 72 °C component 30. A PCR amplified cDNA 1 result. 5% Direct recovery system with gel electrophoretic separation when the, G; BOX EF imaging system (Syngene) cDNA using band therefrom. Also shown to result 3. As a result, 3 as also shown in L6 muscle cells by beverage exhibits high health beverage with red bean processing of mRNA expression were added instead of reduced atrogin-a 1 and MuRF provided 1. This bean extract is muscle cells of the present invention excellent ability in Proteolysis billion number near meaning other. [Experiment example 4] health beverage with red bean ethanol extract of muscle differentiation promoting activities confirmation L6 cells (ATCC) containing 10% FBS DMEM (Hyclone) muscle capillary [...] (Hyclone) is a 6 - well plate with 2 × 105 Cell/mL so him as after inoculation. About 80 to 85% at the time when the cell density, the DMEM medium containing 2% HS and well number (Hyclone) saidin the embodiment to a stand-alone <1-2>Number 25, 50 or 100% ethanol at a concentration of 40 μg/mL high pressure liquid coolant into ethanol extract after melting in a health beverage with red bean, root canal treatment cells induced differentiation of cells. At this time, instead of sample 0. Processing matched group from the group consisting 01% DMSO was used. The process liver 3 times 2, 6 is performed after total during differentiation, using TRIzol reagent (Takara) total RNA was separating. [Experiment example 3] to said isolated RNA is the same method of MyoD and myogenin performed PCR cDNA synthesis and mRNA transcription level has been confirmed. [Table 2] to is the sequence of the primer used for PCR (Bioneer) efined appears. A PCR amplified cDNA 1 result. 5% Direct recovery system with gel electrophoretic separation when the, G; BOX EF imaging system (Syngene) cDNA using band therefrom. Also shown to result 4. As a result, as shown in also 4 MyoD and myogenin expression of mRNA in L6 muscle cells by beverage exhibits high health beverage with red bean processing increases been can be ascertained. This muscle to promote differentiation in muscle cells of the present invention bean extract is an opening through which another substrate. [Experiment example 5] health beverage with red bean extract of muscle-generating active Said method in the embodiment is the same as example 1 experiment <1-5>A high pressure liquid coolant in a health beverage with red bean extract number 40 μg/mL mTOR activity to treatment was assessed. Also shown result 5. As shown health beverage with red bean extract in L6 muscle cells also 5 by a processing of the activity of the mTOR significantly (** P < 0. 01) Increases were confirmed. This bean extract of the present invention has excellent ability to increase the muscle cells in muscle generation means other. [Experiment example 6] a subcritical health beverage with red bean extract of muscle-generating active Said method in the embodiment is the same as example 1 experiment <1-7>A subcritical health beverage with red bean extract subjected to treatment with a 5 μg/mL high pressure liquid coolant in a number mTOR activity was assessed. 6 Also shown to result. 6 Also shown in L6 muscle cells by a processing of the activity of the mTOR as a subcritical health beverage with red bean extract significantly (** P < 0. 01) Increases were confirmed. This subcritical health beverage with red bean extract in muscle cells of the present invention has excellent ability to increase muscle generation means other. [Experiment example 7] health beverage with red bean proteins and peptide of muscle-generating active Said method in the embodiment is the same as example 1 experiment <2-1>, <2-4> <2-5>, <2-6> In a health beverage with red bean protein peptide health beverage with red bean mTOR activity number 40 μg/mL into a high pressure liquid coolant was assessed. 7 Also have shown to result. As a result, 7 as also shown in L6 muscle cells significantly by a processing of the activity of the protein peptide health beverage with red bean-bean mTOR (** P < 0. 01) Increases were confirmed. This bean protein in muscle cells of the present invention peptides which health beverage with red bean muscle rectification through which another substrate. [Experiment example 8] health beverage with red bean mRNA transcription promoting activities of the peptide Said method in the embodiment is the same as in example 2 experiment <2-5>Number 50 or 100 μg/mL mTOR activity and high pressure liquid coolant in a health beverage with red bean processing peptide was assessed. 8 Also have shown to result. As a result, 8 as also shown in L6 muscle cells via peptide health beverage with red bean processing according participating in the synthesis of muscle protein mRNA transfer p provided p70S 6K can be confirmed and p-a 4EBP 1 protein expression amount increased. This muscle protein synthesis in muscle cells of the present invention peptides which facilitate health beverage with red bean mRNA to promote transfer roller means other. [Experiment example 9] health beverage with red bean muscle differentiation promoting activities of the peptide Said method was the same as experiment example 4 database. Health beverage with red bean saidin the embodiment instead of ethanol extract <2-5>High pressure liquid coolant at a concentration of 100 μg/mL or number in a health beverage with red bean 50 peptide after melting, root canal treatment cells induced cell differentiation. At this time, instead of sample 0. 01% DMSO regulated population of processing the electrodes respectively. 9 Also have shown to result. As a result, as shown in 9 also in L6 muscle cells mRNA expression of MyoD and myogenin peptide health beverage with red bean processing according increases been can be ascertained. This muscle to promote differentiation in muscle cells of the present invention peptides which facilitate health beverage with red bean opening through which another substrate. [Experiment example 10] sword red bean ethanol extract of muscle-generating active Said method in the embodiment is the same as example 1 experiment <3-2>A high pressure liquid coolant into ethanol in 100% ethanol extract subjected to treatment with 40 μg/mL sword red bean number mTOR activity was assessed. Also shown to result 10. As also shown in L6 muscle cells by a processing of the sword red bean 10 beverage exhibits high activity of mTOR significantly (** P < 0. 01) Increases were confirmed. This sword red bean extract is muscle cells of the present invention excellent in ability to increase muscle generation in another substrate. [Experiment example 11] health beverage with red bean ethanol extract improving ability while exercising active Health beverage with red bean ethanol extract while exercising as conducting [...] number analysis to evaluate PGC-a 1 alpha activity. COS7 a simian kidney cells (ATCC) 1. 5 Μ 105 Cells/well into 24 - well plate are cultured in behind, using non-modified liposomes (Aptabio, Yongin, Korea) (Addgene, Cambridge, MA, USA) plasmid pGL3-a PGC-a 1 alpha-Luc cell an transformation of his. 4 Injection time transformation, cells 24 with respect to the stabilizing time. Then, said in the embodiment <1-2>100% Ethanol at a concentration of 40 μg/mL DMEM high pressure liquid coolant in a health beverage with red bean extract ethanol from a number after melting, time was 24 cells. Final 24 hours, the cell lysis buffer solution (ELPIS provided Biotech) dissolve NP-a 40 have, as [...] number activity in cell lysate were measured. Also shown to result 11. As a result, 11 as health beverage with red bean extract is also shown in a PGC-a 1 α activity involved in exercising vector significantly (** P < 0. 01) Increases were know. The health beverage with red bean beverage exhibits high performance inhibiting motion has been confirmed. [Experiment example 12] health beverage with red bean beverage exhibits high activity of mitochondrial biosynthesis The same method as example 4 said experiments provide a of abortion. Said in the embodiment 1 - 2 in 100% ethanol at a concentration of 25, 50, 40 μg/mL ethanol from a number a health beverage with red bean extract high pressure liquid coolant after melting, treatment of myotube cells induced differentiation. At this time, instead of sample 0. 01% DMSO regulated population of processing the electrodes respectively. In addition RT a-PCR using specific primers for PCR (Bioneer) stopped when conducting. 12 Also have shown to result. As a result, as shown in 12 also beverage exhibits high health beverage with red bean along treating PGC-a 1 alpha, ERR α, NRF provided 1, Tfam increased expression of mRNA were confirmed. This screening method of the present invention bean extract is deep while exercising the content having a mitochondrial gene expression is excellent in the ability of the empty substrate. [Experiment example 13] health beverage with red bean proteins and peptide of improving ability while exercising active Said method in the embodiment is the same as experimental example 11 <2-1>, <2-2>, <2-3>, <2-4>, <2-5> and <2-6>Each peptide in a health beverage with red bean protein and health beverage with red bean number 40 μg/mL into a high pressure liquid coolant PGC-a 1 alpha activity was assessed. 13 Also shown to result. As a result, as shown in 13 also major factor involved in exercising peptides-bean protein and health beverage with red bean PGC-a 1 α activity significantly (** P < 0. 01) Increases were know. The health beverage with red bean protein and health beverage with red bean has been confirmed that the inhibiting peptide while exercising. [Experiment example 14] health beverage with red bean active biosynthesis of mitochondrial peptide Said method in the embodiment is the same as in example 4 experiment <2-5>In a health beverage with red bean number 50 or 100 μg/mL into a high pressure liquid coolant peptide biosynthesis activity promoting activities of mitochondrial peptide health beverage with red bean was assessed. 14 Also shown to result. As a result, as shown in 14 also peptide health beverage with red bean processing according to the PGC-a 1 alpha, ERR α, NRF provided 1, Tfam increased expression of mRNA were confirmed. This screening method of the present invention peptides which facilitate health beverage with red bean having a mitochondrial content deep while exercising the expression gene is excellent in the ability of the empty substrate. [Experiment example 15] ethanol extract sword red bean improving ability while exercising active Said method in the embodiment is the same as experimental example 11 <3-2>100% Ethanol extract ethanol from a number 40 μg/mL high pressure liquid coolant in a sword red bean subjected to treatment with a PGC-a 1 alpha activity was assessed. 15 Also shown to result. As a result, as shown in also 15 sword red bean extract is motion vector's performance is significantly involved in PGC-a 1 α activity (** P < 0. 01) Increases were know. The sword red bean beverage exhibits high performance inhibiting motion has been confirmed. [Experiment example 16] health beverage with red bean proximal shaft billion active number of the peptide <16-1> Animal breeding and a proximal shaft induction 7 Primary male mouse (C57BL/6N; Young Bio) to a bottom of the myelin basic protein to effective his database. The isomerase (Yonsei Laboratory Animal Reaserch Center; YLARC, Seoul, Korea) population of all animals research center has been effective so that they travel within, breeding room environment temperature 23 ± 2, 55 ± 10% with respect to the relative humidity maintained. Experiment before start, normal group 1 to 5 of total 20 mary military north korean workers party randomly mouse embryo, proximal shaft group, health beverage with red bean 300 administration group, health beverage with red bean 600 divided up the group administration. 1 Between weeks after adapting, by using a methanol (tribromoethanol, Sigma provided aldrich) abdominal cavity of tribromopyrrole 325 mg/kg induced anesthesia. After anesthesia, the kind of administration of RAT muscle (gastrocnemius muscle) with axial army health beverage with red bean to the armrests (hindlimb) pivoted proximal right and right sole skin stapler (skin stapler) (Unidus, Chungcheongbuk-a do, Korea) muscles is moved right to the armrests and damaging not using stapler core part directly after a week is with respect to the maintenance. After week, week number recorded in the stapler core fixed to a stand-alone in the embodiment a method and pivoted horizontal sole <1-2>50% Ethanol at a concentration of 600 mg/kg or 300 mg/kg in a health beverage with red bean extract daily oral administration of ethanol from a number high pressure liquid coolant induced recovery. At this time, instead of his normal group and the proximal axial army sample embodiment for oral administration saline solution. <16-2> Measuring muscular strength And oral administration period expires, (Chatillon force measurement system; Columbus Instrument, Columbus, OH, USA) of RAT strength loss prevention using strength were measured. Placing the mouse muscular strength grader's youngest until one side of RAT rounds and tail, was a successive test times per saw a total 5 embodiment. As a result, as shown in the proximal axial army strength compared to normal group 16 also significantly (# P < 0. 05) Beverage exhibits high strength is significantly reduced but health beverage with red bean along treating (* P < 0. 05) Increased to has been confirmed. This bean extract is proximal shaft of the present invention is superior in a reduced strength due to increase in another substrate. <16-3> Measuring endurance (LE8710MTS; Panlab, Barcelona, Spain) movement of the treadmill device using effective crack was assessed. First starting at a speed of 8 m/min, 1 minutes 1 m/min by speeded up. The mouse shock grid when in contact 0. When the main is set to a value of 2 mA, the mouse 10 seconds of a time stops and experiments with longer thinner electrical impact distance in time were measured. As a result, as shown in group 17 also normal movement of the proximal axial army compared a significant distance and exercise (# P < 0. 05) Beverage exhibits high health beverage with red bean but movable along treating distance and time reduced significantly (* P < 0. 05) Increased to has been confirmed. This bean extract is reduced while exercising due proximal shaft of the present invention is superior in the another substrate. <16-4> Muscle weight measurement After the end of the measuring strength and exercising, experimental animals after anesthesia by injection to the abdominal cavity through a 325 mg/kg of tribromopyrrole methanol (Sigma provided aldrich) core blood-collecting sacrifices for her children. After heartbeat stops confirming, in the armrests [...] segmented in the right damage with an aqueous weight (tibialis anterior muscle) were measured. As a result, as compared to the normal group 18 also shown in injured proximal axial army foreground the muscle which boils the significant weight exercise (# P < 0. 05) Beverage exhibits high health beverage with red bean but significantly reduced weight by processing (* P < 0. 05) Increased to has been confirmed. This bean extract is reduced due to change the proximal shaft of the present invention is superior in muscles that big. Hereinafter, the present invention according to said health beverage with red bean or a drug containing active ingredient for improving performance attainments of excellent for improving health food and pharmaceuticals are described number but, not only specifically described the present invention refers to a bending defining the same bending disclosed. Said beverage exhibits high effect near function improving effect or exercising excellent health beverage with red bean has 1 to 2 according to number and composition ratio such as pharmaceuticals and food composition composition component attainments of his high pressure liquid coolant according to conventional method number. [Attainments number 1] pharmaceuticals Acid number [attainments number 1 - 1] Said in the embodiment 1 to 4 of health beverage with red bean extract, health beverage with red bean peptide, peptide sword red bean or sword red bean extract 50 mg, mixed with conventional acid number manufacturing method by filling the acid number according to determine cellulose 2 g formed thereon a high pressure liquid coolant tight his number. Positive number [attainments number 1 - 2] Said in the embodiment 1 to 4 of health beverage with red bean extract, health beverage with red bean peptide, peptide sword red bean or sword red bean extract 50 mg, determining cellulose 400 mg, 5 mg magnesium stearic acid lubricant homogeneously mixed with conventional positive number manufacturing method by a high pressure liquid coolant according to his number positive number. [Attainments number 1 - 3] capsule number Said in the embodiment 1 to 4 of health beverage with red bean extract, health beverage with red bean peptide, peptide sword red bean or sword red bean extract 30 mg, 100 mg whey protein, determining cellulose 400 mg, 6 mg magnesium stearic acid mixed with conventional capsule filled gelatin capsule according to a high pressure liquid coolant produced his number number number manufacturing method. [Attainments number 2] food [Attainments number 2 - 1] number tank health food Said in the embodiment 1 to 4 of health beverage with red bean extract, health beverage with red bean peptide, peptide sword red bean sword red bean extract or 1000 mg, vitamin A acetate 70 μg, vitamin E 1. 0 Mg, vitamin B1 0. 13 Mg, vitamin B2 0. 15 Mg, vitamin B6 0. 5 Mg, vitamin B12 0. 2 Μg, vitamin C 10 mg, 10 μg biotin, nicotinic acid amide 1. 7 Mg, 50 μg folic acid, Pantothenic acid calcium 0. 5 Mg, iron sulfate 1 number 1. 75 Mg, zinc oxide 0. 82 Mg, magnesium carbonate 25. 3 Mg, 15 mg potassium phosphate number 1, number 2 55 mg calcium phosphate, potassium 90 mg citric acid, 100 mg calcium carbonate, magnesium chloride 24. 8 Mg number can be mixing high pressure liquid coolant, and the repairing material reflecting element and optionally modified embodiment, according to the manufacturing method of said conventional health food components may be mixed together and then, granules and high pressure liquid coolant number, number of health food composition according to conventional method can be use of the bath. [Attainments number 2 - 2] number of health beverage tank Said in the embodiment 1 to 4 of health beverage with red bean extract, health beverage with red bean peptide, peptide sword red bean sword red bean extract or 1000 mg, 1000 mg citric acid, 100 g oligosaccharide, plum concentrate 2 g, a heat treatment is performed according to said conventional health drink manufacturing method number number 1 g taurine applied then 900 ml of whole components may be mixed together, heated with agitation time about 1 85, made sterile by filtration after sterilizing solution 2 L container then health drink composition number acquires sealing quick-bath can be used. [Attainments number 2 - 3] chewing gum 20% By weight of gum base, sugar 76. 9% By weight, 2 to 4% by weight of health beverage with red bean extract 1 weight % perfume and water on said in the embodiment in the embodiment 1, health beverage with red bean peptide, peptide sword red bean or sword red bean extract 0. 1% By weight gum number to his conventional method by combining a high pressure liquid coolant. [Attainments number 2 - 4] candy 60% By weight sugar, glutinous 39. 8 Weight % and perfume 0. 1 To 4% by weight on said in the embodiment 1 of health beverage with red bean extract, health beverage with red bean peptide, peptide sword red bean or sword red bean extract 0. 1% By weight to a high pressure liquid coolant by combining a conventional method was hardly number. [Attainments number 2 - 5] 7 to 1 Force class 25. 59% By weight, gravity 1 class 22. 22% By weight, which is instantly per 4. 80% By weight, sodium chloride 0. 73 Weight %, glucose 0. 78 Weight %, the shortening selling 11. 78% By weight, ammonium 1. 54% By weight, 0 structure of jig. 17% By weight, sulfuric acid natrium bisulfite 0. 16 Weight %, rice 1. 45% By weight, vitamin B 0. 0001% By weight, milk flavor 0. 04% By weight, water 20. 6999% By weight, milk powder 1. 16% By weight, substitute powdered milk 0. 29% By weight, calcium phosphate 0 number 1. 03% By weight, spraying salt 0. 29 Weight % and atomizing oil 7. 27 On said in the embodiment 1 to 4% by weight of health beverage with red bean extract, health beverage with red bean peptide, peptide 1 sword red bean or sword red bean extract. 00% By weight by combining the conventional method was number 7 to a high pressure liquid coolant. According to the present invention, adzuki beans can promote activities and expression of protein or mRNA of a gene involved in differentiation of muscular cells or increasing muscle mass and muscular functions, thereby increasing muscle mass and improving motor ability or myofunction. In addition, adzuki beans are able to prevent, treat, or ameliorate a loss of muscles as well as reduction in motor ability due to various diseases, and thus can be effectively used for foods or drugs as a natural substance without causing side effects in body. COPYRIGHT KIPO 2017 Health beverage with red bean ( According to Claim 1, said composition containing the, C1 To C6 Organic solvents, supercritical fluid a subcritical fluid and at least one solvent selected from the group consisting the obtained by extracting health beverage with red bean characterized, muscle disorders or a pharmaceutical composition for improving performance. Health beverage with red bean proteins or peptide for including active ingredient, or a pharmaceutical composition for improving performance muscle diseases. According to Claim 3, said health beverage with red bean proteins is a i) to v) and obtained by a method comprising the steps of, said health beverage with red bean derived peptides to i) to vii) obtained by the method consisting of the steps characterized, or a pharmaceutical composition for improving performance muscle diseases: i) cyclohexane solvent extracting comminuted dried health beverage with red bean; ii) said step i) extracted from the hexane extract number and a stand-alone, foil to pH 7 by adding water. 0 To 10. 0 Conditions steps; iii) said step ii) left in solution to yield a supernatant by centrifuging; iv) said step iii) obtained supernatant again in pH 2. 0 To 6. 0 Conditions steps; v) said step iv) left in solution precipitation precipitation to obtain a health beverage with red bean proteins centrifuging; vi) said step v) obtained health beverage with red bean proteins without further after enzyme hydrolysis in an enzymatic reaction, filtration of the precipitate industry association step number; and vii) said step vi) number obtain filtrate for reparing over freezing and drying the precipitate in peptides. According to Claim 4, said step vi) and hydrolysis of the enzyme (Alcalase) number [...], focus by step [lu person (Flavourzyme), as new [thu and number (Neutrase), pro other [...] (Protamex) and protein hydrolase - NP consisting of one or more selected from the group consisting (Protease-a NP) protein hydrolysates characterized enzyme composition comprising, muscle disorders or a pharmaceutical composition for improving performance. According to one of Claim 1 to Claim 5, said health beverage with red bean is health beverage with red bean ( According to one of Claim 1 to Claim 5, said muscle disease is a muscle hypofunction, muscle wasting due to degeneration or muscle disease characterized, muscle disorders or a pharmaceutical composition for improving performance. According to Claim 7, said treating muscle disease is tension decay (atony), proximal [...] (muscular atrophy), muscle nutrition symptoms (muscular dystrophy), myasthenia, cachexia (cachexia) and 19 (sarcopenia) least one selected from the group consisting characterized, muscle disorders or a pharmaceutical composition for improving performance. According to one of Claim 1 to Claim 5, while exercising the improvement is degenerative disease, disease, lowering endurance use, lowering a bare foot use, use enervation, muscle waste and depression consists of one or more selected from the group consisting of preventing or treating a disease characterized by Department, muscle disorders or a pharmaceutical composition for improving performance. Health beverage with red bean ( According to Claim 10, said composition containing the, C1 To C4 Organic solvents, supercritical fluid a subcritical fluid and at least one solvent selected from the group consisting the obtained by extracting health beverage with red bean characterized, a drug or a food composition for improving ability while exercising. Health beverage with red bean proteins or peptide active ingredient including, a drug or a food composition for improving ability while exercising. According to Claim 12, said health beverage with red bean proteins is a i) to v) and obtained by a method comprising the steps of, said health beverage with red bean derived peptides to i) to vii) obtained by the method consisting of the steps characterized, while exercising a drug or a food composition for improving ability: i) extracting comminuted dried health beverage with red bean cyclohexane solvent; ii) said step i) and a stand-alone number extracted from the hexane extract, foil to pH 7 by adding water. 0 To 10. 0 Conditions steps; iii) said step ii) left in solution to yield a supernatant by centrifuging; iv) said step iii) obtained supernatant again in pH 2. 0 To 6. 0 Conditions steps; v) said step iv) left in solution precipitation precipitation to obtain a health beverage with red bean proteins centrifuging; vi) said step v) obtained health beverage with red bean proteins without further after enzyme hydrolysis in an enzymatic reaction, filtration of the precipitate industry association step number; and vii) said step vi) number obtain filtrate for reparing over freezing and drying the precipitate in peptides. According to Claim 13, said step vi) and hydrolysis of the enzyme (Alcalase) number [...], focus by step [lu person (Flavourzyme), as new [thu and number (Neutrase), pro other [...] (Protamex) and protein hydrolase - NP consisting of one or more selected from the group consisting (Protease-a NP) protein hydrolysates characterized enzyme composition comprising, a drug or a food composition for improving ability while exercising. According to one of Claim 10 to Claim 14, said health beverage with red bean is health beverage with red bean ( According to one of Claim 10 to Claim 14, said muscle disease is a muscle hypofunction, muscle wasting due to degeneration or muscle disease characterized, a drug or a food composition for improving ability while exercising. According to Claim 16, said treating muscle disease is tension decay (atony), proximal [...] (muscular atrophy), muscle nutrition symptoms (muscular dystrophy), myasthenia, cachexia (cachexia) and 19 (sarcopenia) least one selected from the group consisting characterized, a drug or a food composition for improving ability while exercising. According to one of Claim 10 to Claim 14, while exercising the improvement is degenerative disease, disease, lowering endurance use, lowering a bare foot use, use enervation, muscle waste and depression consists of one or more selected from the group consisting of preventing or treating a disease characterized by Department, a drug or a food composition for improving ability while exercising. Gene amplification Sequence name Sequence number Sequence Direction Atrogin-a 1 Atrogin_F Sequence number 1 5 'A-GTCCAGAGAGTCGGCAAGTC-a 3' Forward Atrogin_R Sequence number 2 5 'A-GTCGGTGATCGTGAGACCTT-a 3' Reverse MuRF-a 1 MuRF_F Sequence number 3 5 'A-TCTACTCGGCCACAGGCGCT-a 3' Forward MuRF_R Sequence number 4 5 'A-CTTGACAGCTCCCGCCGCAA-a 3' Reverse Β-a Actin Actin_F Sequence number 5 5 'A-CTGTGTGGATTGGTGGCTCTAT-a 3' Forward Actin_R Sequence number 6 5 'A-GTGTAAAACGCAGCTCAGTAACA3' Reverse Gene amplification Sequence name Sequence number Sequence Direction MyoD MyoD_F Sequence number 7 5 'A-GGATGGTGCCCCTGGGTCCT-a 3' Forward MyoD_R Sequence number 8 5 'A-TGGCCTTCGCTGTGAGTCGC-a 3' Reverse Myogenin Myogenin_F Sequence number 9 5 'A-TGGGCTGCCACAAGCCAGAC-a 3' Forward Myogenin_R Sequence number 10 5 'A-CAGCCCAGCCACTGGCATCA-a 3' Reverse Β-a Actin Actin_F Sequence number 5 5 'A-CTGTGTGGATTGGTGGCTCTAT-a 3' Forward Actin_R Sequence number 6 5 'A-GTGTAAAACGCAGCTCAGTAACA3' Reverse Gene amplification Sequence name Sequence number Sequence Direction PGC-a 1 alpha PGC_F Sequence number 11 5 'A-ATGTGTCGCCTTCTTGCTCT-a 3' Forward PGC_R Sequence number 12 5 'A-ATCTACTGCCTGGGGACCTT-a 3' Reverse ERR α ERR_F Sequence number 13 5 'A-AAGGGGATGGAGACCACAGT-a 3' Forward ERR_R Sequence number 14 5 'A-TGAGGTGGGAGCTGATAGGG-a 3' Reverse NRF-a 1 NRF_F Sequence number 15 5 'A-TGGACCCAAGCATTACGGAC-a 3' Forward NRF_R Sequence number 16 5 'A-GGTCATTTCACCGCCCTGTA-a 3' Reverse Tfam Tfam_F Sequence number 17 5 'A-GCTTCCAGGAGGCTAAGGAT-a 3' Forward Tfam_R Sequence number 18 5 'A-CCCAATCCCAATGACAACTC-a 3' Reverse Β-a Actin Actin_F Sequence number 5 5 'A-CTGTGTGGATTGGTGGCTCTAT-a 3' Forward Actin_R Sequence number 6 5 'A-GTGTAAAACGCAGCTCAGTAACA3' Reverse
