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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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23-12-2015 дата публикации

Grip module for feeder

Номер: CN0204892779U
Автор: GAO XUEQIN
Принадлежит:

The utility model discloses a grip module for feeder, it includes: the clamp body, variable screw rod group includes variable screw rod of owner and the vice variable screw rod of installing lower extreme on the clamp body, is somebody's turn to do main variable screw rod and fixes with vice variable screw rod spiral, adjustable vice variable screw rod lower extreme of the main variable screw rod of order and clamp body lower extreme interval, the chuck, it is fixed with vice variable screw rod through first screw, and the chuck stretches out in clamp body lower extreme, first pull rod group, it is installed in the clamp body to be connected with vice variable screw rod lower extreme, second pull rod group, it is installed in the clamp body to be connected with vice variable screw rod lower extreme. The utility model discloses an adjust main variable screw rod, can make vice variable screw rod for the oscilaltion of clamp body to adjust the chuck, the operation is simple and easy, and vice ...

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04-07-2012 дата публикации

Application of exenatide acetate or analogue thereof in preparing drug for treating or preventing diabetes complicated with cerebral infarction

Номер: CN0101766811B
Принадлежит:

The invention discloses an application of exenatide acetate or an analogue thereof in preparing a drug for treating or preventing diabetes complicated with cerebral infarction, belonging to the field of pharmacy. The exenatide acetate or the analogue thereof can obviously improve the hemarheology index of a patient, not only effectively mitigate the diabetes manifestation of the patient, but alsoimprove a nerve function, thereby being beneficial to recovering the whole state of illness.

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16-07-2008 дата публикации

Insulin-protamine zinc injection and method for preparing the same

Номер: CN0101219209A
Принадлежит:

The invention pertains to a pharmaceutical preparation field, and in particular relates to a zinc protamine insulin ampoule injection and a preparation method thereof. The zinc protamine insulin ampoule injection comprises insulin, isotonizing agent, antiseptic agent, pH regulator, protamine sulfate and bi-distilled water for injection, wherein, the bi-distilled water for injection contains divalent zinc salt and the concentration of zinc ion is 0.01-0.04g per100000IU of insulin. The injection of the invention has the advantages that minim zinc ion is added into the insulin to form a stable polymer, which stabilizes the insulin and has a prolonged curative effect; the invention has simple, scientific and reasonable preparation and easy manipulation. The insulin can exist in two patterns: firstly, in liquor with quick effect; secondly, combining with protamine sulfate and in precipitation with action characters of both two insulin preparations, which reduces injection time and pain caused ...

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10-02-2010 дата публикации

Preparation method of pharmaceutical preparation and injection of exenatide acetate

Номер: CN0101642562A
Принадлежит:

The invention relates to a preparation method of pharmaceutical preparation and injection of exenatide acetate. The exenatide acetate pharmaceutical preparation is a stable liquid formulation appliedto a plurality of dosing manners. Per 100ml of the pharmaceutical preparation contains at least the exenatide acetate of 0.005-0.4g, preservative of 0.1-0.75g, appropriate amount of buffer and isotonic agent, wherein the preservative is chosen from one or two of chlorobutanol and phenethyl alcohol, with pH value of the pharmaceutical preparation being 3.0-7.0. The preparation method has the following steps: dissolving auxiliary materials of the preservative, the isotonic agent and the buffer according to prescription amount by using water for injection, and immigrating the dissolving solutioninto batching pot; taking the auxiliary solution or the water for injection to dissolve the exenatide acetate; and replenishing the water for injection to total volume and uniformly stirring; filtering the ...

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16-07-2008 дата публикации

Pitavastatin calcium tablet and method for preparing the same

Номер: CN0101219121A
Принадлежит:

The invention relates to a pitavastatin calcium tablet and a preparation method thereof. The pitavastatin calcium tablet comprises a tablet core and a coating. The tablet core comprises components that (by weight percent): pitavastatin 1-5, sodium bicarbonate 5-16, lactose 75-85, croscarmellose sodium 3-6, bonding agent 0.1-0.4, silicon dioxide 1.5-3.0, magnesium stearate plus French chalk 0.5-4.0. The preparation method comprises that (in sequence): raw materials are weighed according to a prescription and screened by a 100-mesh or 80-mesh sieve; the pitavastatin, part of the croscarmellose sodium and the sodium bicarbonate are added gradually with equal quantity and well mixed to obtain a powder mixture; the powder mixture is added with the bonding agent, and well mixed and made into soft material; the soft material is squeezed through a 18-20-mesh sieve to obtain wet granules which are dried under the temperature of 50-70 DEG C; the dry granules are finished with a 20-mesh sieve and ...

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27-05-2009 дата публикации

Technique for extracting mixed rhubarb and aconite

Номер: CN0101439103A
Принадлежит:

The invention relates to the blending extraction process of rhubarb and monkshood in compound Chinese medicine Xiaokening. The blending extraction process of the rhubarb and the monkshood comprises the following steps: mixed powder of the rhubarb and the monkshood is dipped in 6-15 times water for 2-8 hours; and then soak pollution is extracted twice under the assistance of microwave; after extraction liquid is centrifugal and filtered, double extractive supernatant fluids are combined and concentrated till the concentration of drug ingredients is 0.05-0.5g/ml, added with a macroporous resin column for adsorption; firstly, the macroporous resin column is washed with water, and then eluted with ethanol with gradient concentrations; ethanol eluent with 50-80 % of concentration is combined; ethanol is recycled; the blending extractive of the rhubarb and the monkshood is prepared by concentration. The blending extraction process organically combines the microwave assistance extraction process ...

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06-04-2011 дата публикации

Method for determining content of fasudil hydrochloride

Номер: CN0102004139A
Принадлежит:

The invention relates to a method for determining content of fasudil hydrochloride, comprising the following steps: using a potentiometric titrator to dissolve the fasudil hydrochloride in a solvent, adding acid liquor the volume of which is less than or equal to 5% of the total volume to the mixture, and using a titrant to determine the content of the fasudil hydrochloride, wherein the solvent is one or a mixed solvent selected from methyl alcohol, ethanol, water, dimethyl sulfoxide and N,N-dimethylformamide; the acid liquor is the alcoholic solution or aqueous solution of a acid, the acid is one or a mixed acid selected from hydrochloric acid, acetic acid, formic acid, sulphuric acid, phosphoric acid and nitric acid; and the titrant is one or a mixed titrant selected from sodium hydroxide titrant, potassium hydroxide titrant, sodium hydroxide methyl alcohol titrant, potassium hydroxide methyl alcohol titrant, sodium hydroxide ethanol titrant and potassium hydroxide ethanol titrant. The ...

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06-06-2023 дата публикации

Layered carbon fiber graphene aerogel heat-conducting framework material and preparation method thereof

Номер: CN116218483A
Принадлежит:

The invention relates to the field of heat conduction materials, and particularly discloses a layered carbon fiber graphene aerogel heat conduction framework material and a preparation method thereof.The preparation method comprises the following steps that S1, graphene oxide powder, carbon fiber powder and a complexing agent are added into water to be mixed, and carbon fiber graphene oxide dispersion liquid is obtained; s2, carrying out bidirectional freezing on the carbon fiber graphene oxide dispersion liquid by using an ice crystal template method to prepare layered carbon fiber graphene oxide hydrogel; s3, the carbon fiber graphene oxide hydrogel is subjected to freeze drying, and layered carbon fiber graphene oxide aerogel is obtained; s4, the layered carbon fiber graphene oxide aerogel is subjected to a reaction for 80 min to 120 min at the high temperature of 900 DEG C to 1100 DEG C, and the layered carbon fiber graphene aerogel is obtained. In addition, the invention further discloses ...

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07-07-2010 дата публикации

Application of exenatide acetate or analogue thereof in preparing drug for treating or preventing diabetes complicated with cerebral infarction

Номер: CN0101766811A
Принадлежит:

The invention discloses an application of exenatide acetate or an analogue thereof in preparing a drug for treating or preventing diabetes complicated with cerebral infarction, belonging to the field of pharmacy. The exenatide acetate or the analogue thereof can obviously improve the hemarheology index of a patient, not only effectively mitigate the diabetes manifestation of the patient, but also improve a nerve function, thereby being beneficial to recovering the whole state of illness.

Подробнее
23-05-2012 дата публикации

Preparation of glimepiride raw material

Номер: CN0101486674B
Принадлежит:

The invention discloses a preparation method of Glimepiride raw material, which comprises the following steps in sequence: in the presence of K2CO3, a condensation reaction is carried out between a compound A: 4-[2-(3-ethyl-4-methyl-2-keto-3-pyrroline-1-formamido)-ethyl]-benzene sulfonamide and a compound B: trans-4-methyl-cyclohexyl isocyanate of the same molar weight in an organic solvent. The mass ratio of the compound A and K2CO3 is 1:0.8-0.9; the mixture synthetic fluid of a crude Glimepiride product and K2CO3 is filtered in a suction way, and then an extract is added into pure water anddissolved to form a solution. The solution is filtered for removing impurities to obtain the aqueous solution of Glimepiride; a hydrochloric acid solution is added into the aqueous solution of the Glimepiride for acidification and then a crude product is separated; acetone is added into the crude Glimepiride product and then refined, filtered in a suction manner, dried in a vacuum environment to obtain ...

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07-07-2010 дата публикации

New use of pitavastatin calcium and drug aiming at new use

Номер: CN0101766618A
Принадлежит:

The invention relates to a new use of pitavastatin calcium and a drug aiming at the new use, in particular to a new use of pitavastatin calcium in preparing drugs for curing or preventing hyperlipidemia plus cerebral infarction, belonging to the pharmaceutical field. The drug contains 1-5 percent of active ingredient pitavastatin calcium by weight percent and auxiliary materials. Pitavastatin calcium can obviously improve hemorheological index of patients, can effectively relieve the hyperlipidemia manifestations of patients and can improve neurological functions, thereby being beneficial to overall restoration of the patients from illness.

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27-04-2011 дата публикации

Method for synthesizing DP-b99

Номер: CN0102030670A
Автор: Li Wei, Qiao Deshui, Gao Xueqin
Принадлежит:

The invention relates to a method for synthesizing DP-b99, which comprises the following steps of: adding o-nitrophonol A and potassium carbonate into a solvent, dissolving, and adding 1, 2-dibromoethane to obtain B; dissolving B into a solvent, adding into an autoclave, heating to react to obtain C under the environment of palladium, carbon and hydrogen; mixing C with diisopropylamine, sodium iodide and ethyl bromoacetate in acetonitrile, and refluxing to react at 80 to 90 DEG C to obtain D; adding D into ethanol, dropwise adding the water solution of potassium hydroxide, reacting at room temperature, controlling pH value at 2-4, and eluting E; adding E into acetic anhydride containing pyridine, heating to completely react, adding diethyl ether, and precipitating to obtain F; adding sodium into ethylene glycol at room temperature, dropwise adding 1-bromooctane, heating to completely react, adding water, and extracting by using diethyl ether to obtain I; and mixing F with I, heating to ...

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23-06-2010 дата публикации

Principle and method for forming semisolid and solid extruded circumferential self-enhanced plastic pipes

Номер: CN0101746046A
Принадлежит:

The invention relates to a principle and a method for forming semisolid and solid extruded circumferential self-enhanced plastic pipes and is characterized in that the semisolid and solid pipe extruding and forming technology is realized in the circumferential shear stress field in the environment with temperature lower than the melting point temperature of forming material. The technological steps comprise drying raw materials, plasticizing through an extruder, melting and extruding, semisolid and solid extruding, self-enhancing and forming, cooling and setting, and cutting and collecting. The plastic pipe produced by using the method of the invention has the advantages that the strength and the modulus in the circumferential direction of the pipe are obviously enhanced, the performance of the material is configured in an optimizing way, and the degree of satisfaction to the practical requirements on the performance of the material of the pipe subject to internal pressure is promoted.

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14-07-2010 дата публикации

Method for separating and measuring exenatide acetate and blended peptide therein by using liquid chromatography

Номер: CN0101776651A
Принадлежит:

The invention belongs to the field of analytical chemistry, in particular a method for separating and measuring exenatide acetate and blended peptide therein by using liquid chromatography, which is used for separating and measuring an exenatide acetate solution. In a chromatographic column used by the liquid chromatography, a solid phase is alkyl bonding silica gel, and a mobile phase is acetonitrile-phosphate solution, wherein a phosphate solution or a phosphate solution containing a proper amount of acetonitrile is used as a mobile phase A, the concentration of the phosphate solution is 0.01-0.1mol/L, acetonitrile or acetonitrile containing a proper amount of phosphate solution is used as a mobile phase B, and the acetonitrile is used for carrying out gradient elution. Based on volume ratio, the mobile phase B accounts for 10-90 percent of concentration gradient range of the whole mobile phase, and the concentration of the exenatide acetate solution is 0.1-5mg/ml. The exenatide acetate ...

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30-12-2009 дата публикации

Nateglinide tablet and preparation method thereof

Номер: CN0101612133A
Принадлежит:

The invention relates to Nateglinide tablets and a preparation method thereof; in Nateglinide, 30-60% of filler is 3-15% of starch and 10-30% of microcrystalline cellulose, bonding agent is 1-10% of low substituted hydroxypropyl methylcellulose, disintegrant is 15-50% of sodium carboxymethyl starch, fluidizer is 0.1-5% of silica, and lubricant is 0.1-1% of magnesium stearate; the preparation method comprises the following steps: sieving raw materials for standby use; weighing Nateglinide with prescription amount, adding appropriate purified water, blending to prepare soft material, pelletizing and drying to prepare granules of main drug; evenly mixing microcrystalline cellulose, starch and part of sodium carboxymethyl starch, adding substituted hydroxypropyl methylcellulose by equivalently progressive method, evenly mixing to prepare soft material, pelletizing and drying; mixing granules of main drug with granules of accessories, adding residual sodium carboxymethyl starch, magnesium stearate ...

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02-07-2014 дата публикации

Detection analysis method for impurity homopiperazine in fasudil hydrochloride

Номер: CN103901116A
Принадлежит:

The invention discloses a detection analysis method for impurity homopiperazine in fasudil hydrochloride, wherein conductivity detection and an ion chromatography method are adopted to carry out quantitative analysis on the impurity homopiperazine in fasudil hydrochloride. The method has characteristics of simpleness, high precision, good stability, and good reproducibility.

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30-09-2015 дата публикации

Formula of clamp pay -off drive mechanism for feeder

Номер: CN0204672844U
Автор: GAO XUEQIN
Принадлежит:

The utility model discloses a formula of clamp pay -off drive mechanism for feeder, this formula of clamp pay -off drive mechanism for feeder includes: a transmission main shaft, one turns to the mandrel, should turn to mandrel and the perpendicular assembly of transmission main shaft and interlock, and just should turn to the mandrel tip installs an eccentric rotor plate, one send apart from the rocker subassembly, should send to include apart from the rocker subassembly and install the first eccentric seat on eccentric rotor plate and install sending apart from the rocker on first eccentric seat with the mode of the adjustable degree of eccentricity, should send and install on first off -centre seat apart from rocker one end, a first removal pin joint of installation in the other end and the formula of the clamp feeder should be sent and carry out front and back back and forth movement along with the eccentric rotor plate rotation in order to drive first removal seat apart from the rocker ...

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16-05-2023 дата публикации

Double-end servo high-speed roller feeder

Номер: CN116119316A
Принадлежит:

The invention discloses a double-end servo high-speed roller feeding machine which comprises a fixing plate, adjusting screw rods are rotationally connected to the two ends of one side of the fixing plate correspondingly, and mounting bases slidably connected with the fixing plate are in threaded connection to the middles of the two adjusting screw rods correspondingly. The release nut slides along the release screw rod, so that the position of the upper support is adjusted, the distance between the upper gear and the lower gear is indirectly adjusted, the upper roller and the lower roller which are connected with the upper gear and the lower gear are driven to ascend and descend respectively, the release or clamping action is completed, the step of installing a clamping mechanism is replaced, and the labor amount of feeding workers is reduced; the upper rolling wheel and the lower rolling wheel are both designed to be of a single-side floating structure, the two feeding mechanisms are ...

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22-07-2009 дата публикации

Preparation of glimepiride raw material

Номер: CN0101486674A
Принадлежит:

The invention discloses a preparation method of Glimepiride raw material, which comprises the following steps in sequence: in the presence of K2CO3, a condensation reaction is carried out between a compound A: 4-[2-(3-ethyl-4-methyl-2-keto-3-pyrroline-1-formamido)-ethyl]-benzene sulfonamide and a compound B: trans-4-methyl-cyclohexyl isocyanate of the same molar weight in an organic solvent. The mass ratio of the compound A and K2CO3 is 1:0.8-0.9; the mixture synthetic fluid of a crude Glimepiride product and K2CO3 is filtered in a suction way, and then an extract is added into pure water and dissolved to form a solution. The solution is filtered for removing impurities to obtain the aqueous solution of Glimepiride; a hydrochloric acid solution is added into the aqueous solution of the Glimepiride for acidification and then a crude product is separated; acetone is added into the crude Glimepiride product and then refined, filtered in a suction manner, dried in a vacuum environment to obtain ...

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30-09-2015 дата публикации

Formula of clamp feeder is with pressing from both sides material drive mechanism

Номер: CN0204672847U
Автор: GAO XUEQIN
Принадлежит:

The utility model discloses a formula of clamp feeder is with pressing from both sides material drive mechanism, it includes: the transmission main shaft, with the turning to the mandrel, installing in the eccentric rotor plate that turns to the mandrel tip, installing cam pack and first removal seat on eccentric rotor plate of perpendicular assembly of transmission main shaft and interlock, install the thimble that can reciprocate in the first removal seat and install in the first chuck of thimble upper end, the cam pack includes the first eccentric seat installed on eccentric rotor plate, install first rocker on first eccentric seat, the pin joint in first in moving the seat first cam seat and install in the first cam of first cam seat upper end, this first rocker and the pin joint of first cam seat lower extreme, first cam and thimble lower extreme are conflicted and are reciprocated in first removal with the drive thimble. The utility model discloses a mechanical transmission's mode ...

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30-09-2015 дата публикации

Cam drive subassembly for feeder

Номер: CN0204672848U
Автор: GAO XUEQIN
Принадлежит:

The utility model discloses a cam drive subassembly for feeder, this cam drive subassembly for feeder includes: a release camshaft, cup joint in release cam epaxial driving cam axle, install in release camshaft one end and with driving cam axle end connection's release cam and install in proper order in the epaxial brake cam of driving cam, separation and reunion cam, an eccentric cam shaft flange, pay -off cam, the 2nd eccentric cam shaft flange and belt synchronizing wheel, the cut -off rule convex ridge of the oriented outer bellied and distortion of the peripheral shaping of pay -off cam, this cut -off rule convex ridge is the ring -type to separate into first contact zone and second contact zone with pay -off cam periphery. The utility model discloses the structure is comparatively simple, and it is higher to move the precision, and the drive efficiency is comparatively ideal, and work efficiency is higher, in order to cause the utility model discloses higher market competition has ...

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11-10-1995 дата публикации

Process using liquid Na as heat carrier for middle-temp. reaction

Номер: CN0001109905A
Принадлежит:

In middle-temp. reaction of pertro-chemical production, liquid Na is used as heat carrying fluid and the pump immersed in liquid Na is used as circulating power to constitute a complete reaction heat-supply system, so that the heat from heating furnace can be indirectly supplied to reactor, and the temp. needed by reactor is controlled by regulating work state of said pump. High-precision deoxidant and drying agent are chosen to prevent oxygen and water from going in Na circulation system and reasonable gas pressure in circulating system is maintained.

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16-07-2008 дата публикации

Telmisartan dispersible tablet and method for preparing the same

Номер: CN0101219120A
Принадлежит:

The invention discloses a telmisartan dispersible tablet and a preparation method thereof. The Telmisartan dispersible tablet comprises a telmisartan, an excipient, a cosolvent, a filling agent, a disintegrating agent; a bonding agent, a lubricant and a fluidizer, wherein, the fluidizer is sodium hydroxide and meglumine and the excipient is polyvidone; surfactant and emulsifier are excluded in the telmisartan dispersible tablet. The preparation method is that: the telmisartan and auxiliary materials are screened; the telmisartan, the cosolvent, and the excipient are added into a solvent in sequence to be dissolved; then the filtrate is spray-dried to obtain principal telmisartan granules; part of the filling agent, part of the lubricant and disintegrating agent are well mixed in sequence and then added with the bonding agent, and then palletized to obtain the auxiliary material granules; other auxiliary materials are added into the principal telmisartan granules and the auxiliary material ...

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25-11-2009 дата публикации

Oligonucleotide chip and application thereof

Номер: CN0101586149A
Принадлежит:

The invention discloses an oligonucleotide chip labeling a random primer PCR amplification based on a biotin-avidin-cy3 reaction system, which is made by a substrate, and CMV, HSVI, RV, EBV or TB pathogen probes, a negative control, a positive control and a blank control that are coated on the substrate in an array way, wherein the substrate is a surface aldehyde glass slide; the pathogen probes are 10 of CMV-1, CMV-2, HSVI-1, HSVI-2, RV1, RV2, EBV1, EBV2, TB1 and TB2 probes with 70mer; the positive control is a synthesized marker probe; and the blank control is double distilled water. The invention performs the biotin-11-dUTP amplified labeling to various pathogen target sequences by using the random primer and detects the pathogen by adopting a method of increasing the labeling efficiency through using a biotin-avidin-cy3 signal amplification system, has high detection sensitivity and obviously shortens the detection cost and the detection time. The technical system can be suitable to ...

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18-04-2023 дата публикации

Polymer melt composite vibration injection molding device

Номер: CN115972478A
Принадлежит:

The invention discloses a polymer melt composite vibration injection molding device which comprises an injection molding machine, a composite vibration system and an injection mold, and the biggest difference from common injection molding is the composite vibration system of the device. The composite vibration system comprises a low and medium frequency hydraulic vibration system and a high frequency ultrasonic vibration system, the hydraulic vibration system is composed of a hydraulic pump, a rotary valve, a hydraulic cylinder, vibration rods and the like, the vibration rods stretch into a polymer melt flow channel, the number of the vibration rods is even, and the vibration rods can be divided into two groups to conduct reciprocating vibration in the same direction or in the opposite directions at the same time so as to achieve pressure vibration or shear vibration of melt. The ultrasonic vibration system is composed of an ultrasonic generator, a transducer, an amplitude-change pole and ...

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16-06-2010 дата публикации

Two-phase isophane zinc recombinant human insulin injection and preparation method thereof

Номер: CN0101732245A
Принадлежит:

The invention relates to a two-phase isophane zinc recombinant human insulin injection and a preparation method thereof. A specification I comprises the following components in part by weight: 300,000IU of recombinant human insulin, 42 to 54g of isosmotic agent, 7.5 to 1.5g of preservative, 14.4 to 15.0g of pH regulator and 0.45 to 0.9g of protamine sulfate. A specification II comprises the following components in part by weight: 400,000IU of recombinant human insulin, 140 to 180g of isosmotic agent, 25 to 35g of preservative, 48 to 50g of pH regulator and 1.5 to 3.0g of protamine sulfate. Both preparation methods of both specifications of the two-phase isophane zinc recombinant human insulin comprise a step of mixing solution A and solution B, wherein the solution A is prepared by adding water for injection into the recombinant human insulin, the isosmotic agent, the preservative and the pH regulator for dissolving; then slowly adding an appropriate amount of water for injection with the ...

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02-07-2014 дата публикации

Purification and decoloration method for cinepazide

Номер: CN103896878A
Принадлежит:

The invention discloses a purification and decoloration method for cinepazide, wherein the pH value of a cinepazide hydrochloride aqueous solution is directly adjusted to achieve the weakly basic state, and the filtration operation is matched to separate pigments, water soluble impurities and the salt cinepazide. The method has characteristics of simple operation, high yield, significant color removing, and effective product quality improving so as to improve enterprise benefits.

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24-02-2010 дата публикации

Oligonucleotide chip capable of detecting five enteroviruses simultaneously and application thereof

Номер: CN0101654713A
Принадлежит:

The invention discloses an oligonucleotide chip capable of detecting five enteroviruses simultaneously and an application thereof. The chip comprises a substrate, probes of pathogens of five enteroviruses coated on the substrate, negative contrast, positive contrast and blank contrast, wherein the probes of pathogens are five 54-70mer of HAV-P, ROV-P, NOV-P, ASV-P and ADV-PV1 probes. The chip of the invention adopts multiple PCR to amplify a plurality of target sequences of pathogens simultaneously and uses the downstream primer Tamara labeling method to perform fluorescence labeling to PCR product, the labeled PCR product is hybridized with the chip to realize the accurate detection of pathogens, the detection sensitivity is equal to that of PCR and the specificity is high. The detectionefficiency and accuracy are obviously shortened. The technology system of the invention is applicable to fields such as sea water and marine life specimens monitoring, food hygiene surveillance, customs ...

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30-12-2009 дата публикации

Cilostazol capsule and preparation method thereof

Номер: CN0101612137A
Принадлежит:

The invention relates to a Cilostazol capsule and a preparation method thereof. The components comprises Cilostazol, lactose and microcrystalline cellulose as filler, hydroxypropyl methylcellulose as binding agent, Hyprolose as disintegrant, aerosil as glidant and magnesium stearate as lubricant. The preparation method is that Cilostazol is smashed into fine powder with average grain diameter of 10-15mu m followed by 100 mesh sieve, lactose, microcrystalline cellulose, hydroxypropyl methylcellulose, Hyprolose, aerosil and magnesium stearate are sieved for standby use; Cilostazol powder and 50-90% of the filler are mixed evenly, the binding agent is added for preparing into soft material, sieving is carried out for preparing wet granulation, the wet granules are dried, smashed and sieved to prepare main drug granules; the residual filler is mixed evenly, water is added fro preparing soft material, sieving is carried out for preparing wet granules, forced air drying is carried out at 60 DEG ...

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23-06-2010 дата публикации

Extrusion forming principle and method of plastic tubes for axial self-reinforcement

Номер: CN0101746045A
Принадлежит:

The invention relates to an extrusion forming principle and method of plastic tubes for axial self-reinforcement, which is characterized by realizing extruded tube forming process under an axial tensile stress field with the function of converging flow, wherein the process comprises the following steps in sequence: raw material drying, extruder plasticizing, melt extruding, forming for axial self-reinforcement, cooling shaping and cutting and collecting. The strength and modulus of the plastic tubes produced by the method are simultaneously reinforced axially, thus configuring the properties of the materials more optimally and better satisfying the practical demands of the tubes for the material properties. After the tubes are reinforced, the axial orientation degrees of the tubes are higher than the axial orientation degrees of the conventional tubes, the wafers of the reinforced tubes are thicker and the reinforced tubes have higher crystallinity, therefore the heat resistance of the ...

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11-02-2015 дата публикации

Crane and hoisting mechanism thereof

Номер: CN104340864A
Автор: MA QIANG, GAO XUEQIN
Принадлежит:

The invention discloses a crane and a hoisting mechanism thereof. The hoisting mechanism comprises a first motor, a second motor, a first speed reducer, a second speed reducer, a first coiling block, a second coiling block, a first working brake and a second working brake, wherein the first working brake brakes the first speed reducer; the second working brake brakes the second speed reducer; the first coiling block is coaxially connected with the second coiling block; and the first motor and the second motor commonly drive or independently drive the first speed reducer and the second speed reducer, so as to drive the first coiling block and the second coiling block to act. According to the hoisting mechanism, the first coiling block and the second coiling block can be respectively driven to synchronously act through a plurality of transmission chains; when any motor, speed reducer and the like break down, the first coiling block and the second coiling block still can be in a working state ...

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30-09-2015 дата публикации

Revolving stage mechanism for feeder

Номер: CN0204672849U
Автор: GAO XUEQIN
Принадлежит:

The utility model discloses a revolving stage mechanism for feeder, it includes flange assembly and installs the revolving stage on flange assembly and set up in the cam roller bearing in the revolving stage outside with rotatable mode, the mounting groove has inwards been seted up along its side level in this revolving stage upper end, and this revolving stage upper end level wears to be equipped with the fixed pin, and a rack barrel is installed to this fixed pin one end, and this rack barrel falls into in the mounting groove, first length change gear is installed to this fixed pin other end, and this first length change gear is located the opposite side of revolving stage for the mounting groove, be provided with the gear adjusting spindle that is used for adjusting feed length in the feeder, this gear adjusting spindle tip is provided with second length change gear, and this second length change gear stretch into in the mounting groove to with cydariform gear engagement, when the revolving ...

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25-06-2014 дата публикации

New use of acarbose

Номер: CN103877106A
Автор: GAO XUEQIN, QIAO DESHUI
Принадлежит:

The invention provides a use of acarbose in the preparation of medicines for treating and/or preventing diabetes combined with coronary heart disease. Clinical test researches in the invention show that acarbose has a better curative effect on diabetic patients with coronary heart disease than on non-diabetic patients with coronary heart disease, and acarbose can effectively alleviate the diabetic symptoms of patients, and can also improve the vascular nerve function, so acarbose is beneficial to recover the overall conditions of the patients, and has a significant treatment and/or prevention effect on the diabetes combined with coronary heart disease.

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25-06-2014 дата публикации

Synthetic method of Clopidogrel hydrogen sulfate of crystal form I

Номер: CN103880858A
Автор: LI WEI, QIAO DESHUI, GAO XUEQIN
Принадлежит:

The invention discloses a synthetic method of Clopidogrel hydrogen sulfate of crystal form I. Stable Clopidogrel hydrogen sulfate of crystal form I is synthesized by treating Clopidogrel hydrogen sulfate of crystal form II as a raw material and ethyl acetate as a phase transition solvent. The stable Clopidogrel hydrogen sulfate of crystal form I can be successfully synthesized by treating Clopidogrel hydrogen sulfate of crystal form II as a raw material. The method can realize easy product collection, and is suitable for industrial enlarged production.

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16-12-2015 дата публикации

Heart postoperative adjustable joint fixing device

Номер: CN0204863606U
Принадлежит:

The utility model provides a heart postoperative adjustable joint fixing device, includes around joint fixed band (1), fixed plate (2), thread gluing (3), being formed by the preparation of the textile cloth of two -layer gas permeability around joint fixed band (1), fill silk floss between two -layer cloth, two -layer cloth is at the fixed connection of edge, and lower edge around joint fixed band (1) is equipped with and is used for getting the opening of putting fixed plate (2) in joint fixed band (1) for fixed plate (2) three edge -fixed, is equipped with thread gluing (3) at the both ends around joint fixed band (1) length direction, the thread gluing includes box (31) and the son knot (32) of mutual adhesion. The utility model discloses convenient for material collection, do manual work simple, with low costs, the use wide, not only is applicable to the patient of heart postoperative guardianship, can be used to the ward heart simultaneously and get involved postoperative patient's ...

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27-04-2011 дата публикации

New purpose for compound aloes and new purpose-based medicament

Номер: CN0102028852A
Автор: Gao Xueqin, Qiao Deshui
Принадлежит:

The invention belongs to the field of pharmacy, and relates to a new purpose for compound aloes, a new purpose-based medicament, new use of the compound aloes in the preparation of medicaments for treating or preventing hyperlipidemia with cerebral infarction. The compound aloes can improve the hemorheological indexes of patients obviously, relieve the expression of the hyperlipidemia with cerebral infarction effectively, and improve the neural function, so the compound aloes are favorable for the recovery of the integral bodies of the patients from illness.

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30-01-2008 дата публикации

Roll processing flaw detecting method

Номер: CN0101113971A
Принадлежит:

The invention provides a crack detection method of roll dressing, the steps of which is that: scrapping the surface of the rolls after processing; connecting magnetic particle detector to the electricity; spraying black oil magnetic suspension on the defectoscopy of the roll surface; opening the switch of the magnetic particle detector and adjusting the angle of the two contact heads and being positioned at the black oil magnetic suspension sprayed. After observation of the roll surface, magnetic powder can be found at the crack if crack exists; then carrying on flaw inspection in a plurality of different places on the roll surface, the process should be continued if crack is observed until no crack is detected. The invention has the beneficial effects that tiny crack on the roll surface is efficiently detected after roll processing by the detection method. Then appropriate procession can be continued which not only cuts down the loss during raising the processing capacity blindly, but ...

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16-06-2010 дата публикации

Method for preparing main ester alkaloid of traditional Chinese medicine monkshood by liquid chromatography separation

Номер: CN0101732431A
Принадлежит:

The invention relates to a method for preparing main ester alkaloid of traditional Chinese medicine monkshood by liquid chromatography separation. The invention establishes and prepares the chromatogram by linear amplification and optimization based on chromatogram analysis, and the main ester alkaloid of traditional Chinese medicine monkshood is prepared by separation; six mono-ester diterpene alkaloids and three diester diterpene alkaloids are prepared by separating from the traditional Chinese medicine monkshood, wherein six mono-ester alkaloids are obtained by separation or the first time, the purity of the obtained alkaloids are more than 99.3%, in chromatographic columns for analyzing and preparing the chromatogram, all stationary phases are octadecylsilane chemically bonded silica, all mobile phases are organic phases-acetate buffer systems, the proportion of the organic phases to the mobile phases is 20-70%, the organic phase is methanol or acetonitrile, the acetate buffer systems ...

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23-07-2008 дата публикации

Colour development protein chip using BCIP/NBT as substrate as well as application in detection of autoantibody thereof

Номер: CN0101226192A
Принадлежит:

The invention discloses a color protein chip which substrate is BCIP/NBT. The invention is composed of a substrate, an array, 12 antigens coated on the array, negative contrast, positive contrast and blank contrast, wherein the substrate is a glass slide decorated by APES, the kinds and point sample densities of the 12 antigens are 520ug/ml ANA, 465ug/ml Ro-60, 530ug/ml La/SSb, 530ug/ml Jo-1, 525ug/ml Scl-70, 520ug/ml Sm, 615ug/ml Ro-52/SSa, 340ug/ml RF, 465ug/ml CCP, 410ug/ml u1RNP, 490ug/ml CENP-B, 580ug/ml dsDNA. The invention uses the alkali phosphatase coloring method whose substrate is BCIP/NBT as the final check signal of protein chip to be widely used for self antibody check, while the check sensitivity has higher coincidence rate than prior art, with reduced check cost and time. The invention can be used in clinical check, sanitary supervision, regular sanitary supervision and scientific research or the like.

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19-03-2014 дата публикации

Production of bacillus coagulans solid-state fermentation feed rich in phenyllactic acid and preparation of the feed

Номер: CN103636923A
Принадлежит:

The invention relates to production of bacillus coagulans solid-state fermentation feed rich in phenyllactic acid by utilization of a solid state fermentation technology. The bacillus coagulans is utilized to perform solid state fermentation. The yield of the phenyllactic acid in a sample is determined by controlling a fermentation process, extracting the phenyllactic acid in the late period of fermentation and exploring detection conditions. Finally, the bacillus coagulans solid-state fermentation feed having the highest yield of the phenyllactic acid is obtained by optimizing culture media and adding substrates. The feed effectively increases the laying rate of laying hens and reduces the death and culling rate and the feed-egg ratio. The optimum using concentration is 0.15%. The phenyllactic acid is a novel antibacterial substance, and has functions of improving animal immunity, improving livestock and poultry meat quality, reducing the quantity of escherichia coli in the livestock, ...

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31-08-2011 дата публикации

Colour development protein chip using BCIP/NBT as substrate as well as application in detection of autoantibody thereof

Номер: CN0101226192B
Принадлежит:

The invention discloses a color protein chip which substrate is BCIP/NBT. The invention is composed of a substrate, an array, 12 antigens coated on the array, negative contrast, positive contrast and blank contrast, wherein the substrate is a glass slide decorated by APES, the kinds and point sample densities of the 12 antigens are 520ug/ml ANA, 465ug/ml Ro-60, 530ug/ml La/SSb, 530ug/ml Jo-1, 525ug/ml Scl-70, 520ug/ml Sm, 615ug/ml Ro-52/SSa, 340ug/ml RF, 465ug/ml CCP, 410ug/ml u1RNP, 490ug/ml CENP-B, 580ug/ml dsDNA. The invention uses the alkali phosphatase coloring method whose substrate is BCIP/NBT as the final check signal of protein chip to be widely used for self antibody check, while the check sensitivity has higher coincidence rate than prior art, with reduced check cost and time. The invention can be used in clinical check, sanitary supervision, regular sanitary supervision and scientific research or the like.

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30-09-2015 дата публикации

Formula of clamp feeder

Номер: CN0204672846U
Автор: GAO XUEQIN
Принадлежит:

The utility model discloses a formula of clamp feeder, this formula of clamp feeder includes: a frame, a leading guide device, it is including installing the forestock flitch on the frame and install preceding guide roller train on the forestock flitch in proper order, be used for material surface cleaning's clean board, back guide roller train, one presss from both sides tight material feeding unit, and it is including installing in the pressing from both sides tight material and press from both sides material conveying subassembly and press from both sides material locating component with this clamps material conveying subassembly complex what the horizontal direction removed of back guide roller train rear, presss from both sides tight material and when the horizontal direction is move along, presss from both sides and expect that locating component is at loosening the state when pressing from both sides material conveying subassembly, expect when pressing from both sides that the conveying ...

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14-07-2023 дата публикации

Application of Beclin1 as Sphk1 transcriptional suppressor in preparation of adult hematopoietic regulation medicine

Номер: CN116421706A
Принадлежит:

The invention discloses an application of Beclin1 as an Sphk1 transcription inhibitor in preparation of an adult hematopoietic regulation medicine. Researches prove that in adult hematopoietic organ bone marrow, Beclin1 exists in cytoplasm and also exists in cell nuclei in quantity. Meanwhile, the Beclin1 can be combined with DNA in a cell nucleus to participate in regulation and control of expression of Sphk1, so that stable metabolism and normal function of adult stem progenitor cells are maintained, that is, in adult hematopoietic organ bone marrow, the Beclin1 can be used as a transcription inhibition factor to participate in hematopoietic generation regulation and control without depending on a classical autophagy function, and the Beclin1 is expected to be used for preparing medicines for regulating and controlling adult hematopoiesis. In addition, the research on the non-classical autophagy function of the Beclin1 can be further promoted.

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25-06-2014 дата публикации

Calcium dobesilate dispersible tablet and preparation method thereof

Номер: CN103877038A
Принадлежит:

The present invention discloses a calcium dobesilate dispersible tablet and a preparation method thereof. The calcium dobesilate dispersible tablet contains, by weight, a main drug calcium dobesilate, and auxiliary materials such as 1-42% of cross-linked povidone, 0.5-42% of microcrystalline cellulose, 2-44% of lactose and 0.01-15% of magnesium stearate. According to the present invention, a direct powder tabletting method is adopted to prepare the calcium dobesilate dispersible tablet; the method has characteristics of simple operation, time saving, reduction of times of calcium dobesilate exposed to air and light, and reduction of moisture absorption and light instability; the prepared calcium dobesilate dispersible tablet has a smooth surface morphology, and can be completely disintegrated within 2 min and screened with a 2# sieve, and the dissolution rate of the prepared calcium dobesilate dispersible tablet in water and a dilute hydrochloric acid solution within 5 min can achieve more ...

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09-02-2011 дата публикации

Febuxostat dispersible tablet and preparation method thereof

Номер: CN0101966163A
Принадлежит:

The invention relates to a febuxostat dispersible tablet and a preparation method thereof. The febuxostat dispersible tablet comprises febuxostat as a main material and a diluent, a disintegrant, a binder, a flow aid, a lubricant and other assistants as auxiliary materials, wherein the flow aid is silicone dioxide, and the lubricant is magnesium stearate. The febuxostat dispersible tablet is prepared from the following components in percentage by weight: 5-30% of the febuxostat, 20-80% of the diluent, 5-30% of the disintegrant, 0.1-5% of the binder, 1-10% of the silicone dioxide, 0.2-5% of the magnesium stearate and 2-8% of other assistants. The febuxostat dispersible tablet prepared by adding a proper amount of auxiliary materials into crushed febuxostat has the advantages of rapid and complete drug dissolution and stable quality, is suitable for long-term storage and convenient to use, and the bioavailability of human bodies on drugs is increased so as to increase curative effect.

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02-02-2011 дата публикации

Mix extraction process for radix astragali and rhubarb

Номер: CN0101961392A
Принадлежит:

The invention relates to a mix extraction process for radix astragali and rhubarb, which comprises the following steps: soaking the mixed powder of radix astragali and rhubarb for 2-8h in 6-15 times of water, extracting by carrying out microwave digestion on the soak solution twice, carrying out centrifugal filtration on the extract liquids, merging the supernatants in two extraction processes, concentrating until the drug concentration is 0.05-0.5 g/ml, adsorbing by adding the concentrated solution into macroporous resin columns, washing the macroporous resin columns with water, eluting the macroporous resin columns with ethanol with gradient concentrations for many times, merging the ethanol eluents of which the concentration is 50-80%, recycling the ethanol, and concentrating to obtain the mixed extract of radix astragali and rhubarb. By combining the microwave assisted extraction technique with macromolecule adsorption technique, the invention has the technical characteristics of high ...

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20-04-2011 дата публикации

Method for synthesizing and purifying Fasudil hydrochloride

Номер: CN0102020636A
Принадлежит:

The invention relates to a method for synthesizing and purifying Fasudil hydrochloride, comprising the following steps of: adding N,N-dimethylformamide and thionyl dichloride to 5-isoquinoline sulfonic acid to obtain a 5-isoquinoline sulfonyl chloride hydrochloride; adding the 5-isoquinoline sulfonyl chloride hydrochloride, water and sodium bicarbonate to dichloroethene to obtain a 5-isoquinoline sulfonyl chloride solution; dripping the 5-isoquinoline sulfonyl chloride solution to homopiperazine at zero DEG C to obtain a hexahydro-1-(5-sulfonyl isoquinoline)-1(H)-1,4-benzodiazepine solution; removing impurities in three steps; adjusting the pH value to be 4.5-5.5 with an acidizing fluid, extracting, and discarding an organic phase dissolved with a dipolymer impurity; adjusting the pH value to be 9.5-10.5 with alkali, extracting and discarding a water phase dissolved with homopiperazine impurities and a majority of pigments; removing the residue pigment by passing through silica gel; and ...

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23-06-2010 дата публикации

Low-temperature near-melting point extrusion molding principle and method for two-way self-reinforced plastic pipe

Номер: CN0101746040A
Принадлежит:

The invention relates to a principle and a method for producing and manufacturing various plastic pipe workpieces, which are characterized in that: an extrusion molding process is implemented under a shear stretch two-way composite stress field in a temperature environment where the melting-point temperature of the molded material is slightly higher. The method comprises the following processing steps: drying raw materials, plastifying the raw materials by using an extruder, extruding melt, low-temperature near-melting point two-way self-reinforced molding, cooling and shaping, and cutting and collecting. The strength and modulus of the plastic pipe produced by the method are both reinforced in the axial direction and the circumferential direction; weld mark defects are eliminated; the strength and modulus of the pipe in the circumferential direction can exceed or be close to those of the pipe in the axial direction, so that the material performance is optimally configured, and the actual ...

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20-05-2009 дата публикации

Glimepiride tablet and preparation method thereof

Номер: CN0101433524A
Принадлежит:

The invention relates to a Glimepiride tablet and a preparation method thereof. The Glimepiride tablet comprises the components such as Glimepiride, a filling agent or a diluting agent, an adhesive and a lubricating agent, wherein the filling agent or the diluting agent is lactose, pregelatinized starch and microcrystalline cellulose; the adhesive is hydroxypropyl methylcellulose; the lubricating agent is magnesium stearate; and the components according to weight percentage are as follows: 1 to 10 percent of the Glimepiride, 20 to 35 percent of the lactose, 13 to 30 percent of the microcrystalline cellulose, 45 to 60 percent of the pregelatinized starch, 0 to 5 percent of the hydroxypropyl methylcellulose, and 0.1 to 1 percent of the magnesium stearate. The Glimepiride tablet has few ingredients and easily obtained simple auxiliary materials, the prepared tablet can be disintegrated quickly, can be completely disintegrated within 3 minutes, can achieve even dispersing state, can be dissolved ...

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30-12-2015 дата публикации

Pay -off sliding block set spare for feeder

Номер: CN0204912530U
Автор: GAO XUEQIN
Принадлежит:

The utility model discloses a pay -off sliding block set spare for feeder, this pay -off sliding block set spare for feeder includes: but the first slide rail of fixed mounting in the feeder, install second slide rail in the feeder, cup joint slide block body and movable mounting on first, second slide rail on slide block body and the chuck seat that can reciprocate in slide block body with the luffing motion mode, mated first, the second meniscus of this chuck seat lower extreme installation, the second slide rail outside is provided with a slide bar, and this slide bar falls into between first, the second meniscus, when second slide rail luffing motion, the slide bar cooperation in this second slide rail outside is first, reciprocate on the slide block body under the second meniscus drive chuck seat. The utility model discloses can realize simultaneously pressing from both sides and foresee the pay -off, and the structure is very simple, the operation is smooth and easy, and is with low ...

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26-07-2000 дата публикации

Process for preparing sodium isooctoate

Номер: CN0001261069A
Принадлежит:

A process for preparing sodium isooctate includes the steps of reaction of isotanoic acid on alkali containing Na ions or alkaline Na salt at 40-100 deg.C to generate sodium isooctate and direct drying or spray drying. Its advantage is high purity. Said sodium isooctate can be used for medicine which is higher quality output rate and stability.

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30-12-2009 дата публикации

Preparation technique of low molecular weight sodium heparin used for injection

Номер: CN0101612130A
Принадлежит:

The invention relates to a preparation technique of low molecular weight sodium heparin used for injection, which is implemented by using water for injection to dissolve low molecular weight sodium heparin of prescription under the aseptic condition, adding into a batching tank, additionally adding the water for injection to the total volume, formulating solution and stirring uniformly; regulating pH value to 5.5-7.0 with diluted acid or diluted alkali solution; sterilizing and filtering the solution with 0.2 mu m double-layered microfiltration membrane, bulking the feed liquor and carrying out half tamponade; freezing the feed liquor to the temperature of minus 45-minus 40 DEG C, keeping the temperature for at least 3h, controlling the temperature of a condenser at minus 50-minus 45 DEG C, starting a vacuum pump, controlling at 18-20 Pa for sublimation, controlling the plate temperature at 2-4 DEG C/h and raising the temperature to 28-32 DEG C, keeping the temperature for 3-4h, carrying ...

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23-02-2011 дата публикации

Telmisartan dispersible tablet and method for preparing the same

Номер: CN0101219120B
Принадлежит:

The invention discloses a telmisartan dispersible tablet and a preparation method thereof. The Telmisartan dispersible tablet comprises a telmisartan, an excipient, a cosolvent, a filling agent, a disintegrating agent; a bonding agent, a lubricant and a fluidizer, wherein, the fluidizer is sodium hydroxide and meglumine and the excipient is polyvidone; surfactant and emulsifier are excluded in the telmisartan dispersible tablet. The preparation method is that: the telmisartan and auxiliary materials are screened; the telmisartan, the cosolvent, and the excipient are added into a solvent in sequence to be dissolved; then the filtrate is spray-dried to obtain principal telmisartan granules; part of the filling agent, part of the lubricant and disintegrating agent are well mixed in sequence and then added with the bonding agent, and then palletized to obtain the auxiliary material granules; other auxiliary materials are added into the principal telmisartan granules and the auxiliary material ...

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20-05-2009 дата публикации

Method for preparing twelve kinds of composite vitamins for injection

Номер: CN0101433547A
Принадлежит:

The invention relates to a preparation method for a compound 12-vitamin preparation, which comprises the following steps: using glycin as filling agent, using glycocholic acid and lecithin as solubilizer, adding sodium hydroxide solution into partial water for injection containing the glycocholic acid solubilizer to prepare clarifying solution, adding the clarifying solution into the water for injection containing the lecithin solubilizer under stirring, and using hydrochloric acid solution to adjust pH to be 2.5 to 3.5; adding three vitamins, namely vitamin A palmitate, racemized alpha-tocopherol and vitamin D3, into the mixture, and using the hydrochloric acid solution to adjust the mixture to be clear under stirring; finally adding nine vitamins, namely glycin and cocarboxylase tetrahydrate, riboflavin sodium phosphate, vitamin B12, vitamin B6, vitamin C, nicotinic amide, folic acid, biotin and dexpanthenol, into the mixture, and adding balanced water for injection; and adjusting pH ...

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02-12-2015 дата публикации

Correlation type speedtransmitter calibrating device

Номер: CN0204832244U
Принадлежит:

The utility model discloses a correlation type speedtransmitter time parameter calibrating device especially relates to the calibration technique field of time parameter. The utility model discloses a rated rotational frequency source, n central angle sector and position control device. N central angle sector is installed on the rotation axis of rated rotational frequency source, install correlation type speedtransmitter on the position control device, the position control device is adjusted correlation type speedtransmitter and is made its and central alignment of rated rotational frequency source rotation axis. The utility model discloses a profile rotational speed source, special n central angle sector and position control device can be realized turning into the pivot speed measurement to the space rate measurement to correlation type speedtransmitter's whole calibration, have solved the measurement that sensor portion divides, have improved accuracy, reduce and do not calibrate the ...

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02-07-2014 дата публикации

Preparation method of high purity cinepazide maleate

Номер: CN103896879A
Принадлежит:

The invention discloses a preparation method of high purity cinepazide maleate. According to the preparation method, chloroacetyl chloride is reacted with pyrrolidine so as to obtain chloracetyl pyrrole; chloracetyl pyrrole is reacted with anhydrous piperazine so as to obtain 1-piperazineacetyl pyrrolizidine; 1-piperazineacetyl pyrrolizidine is reacted with 3,4,5-trimethoxy cinnamoyl chloride so as to obtain cinepazide free alkali; and the cinepazide free alkali is subjected to acid and alkali treatment and recrystallization so as to obtain high purity cinepazide maleate products. According to the preparation method, impurities and pigments generated in reaction processes are removed based on the solubility difference of compounds in different solvents in each reaction step; the preparation method is simple; treatment is convenient; solvents with low toxicity and high safety are used; and product yield and product quality are high.

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16-07-2008 дата публикации

Method for producing pitavastatin calcium raw material

Номер: CN0101219991A
Принадлежит:

The invention relates to a method for preparing the raw materials of pitavastatin calcium, which uses an (E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-5-hydroxyl-3- carbonyl-6-heptene acid ester as a beginning raw material to generate a heptenoic acid through being reduced and reacted by adding an alkali and an acid; a D-(+) benzyl methylamine is added to generate a mixture of a benzyl methylamine salt, and crystallize to separate out a (3R, 5S)-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-6- heptenoic acid D-(+) benzyl methylamine through the different solubility of the mixtures in a separating agent, and the separating agent is a mixed liquid of a methyl isobutyl ketone and an acetone or an ethanol; finally adds lye to hydrolyze and prepare the pitavastatin calcium salt. The method of the invention is selectively reduced to a pair of isomers by using a determined reduction agent, generates salt by reacting with the D-(+) benzyl methylamine and effectively separates ...

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23-06-2010 дата публикации

Extrusion forming principle and method of plastic tubes for biaxial self-reinforcement

Номер: CN0101746044A
Принадлежит:

The invention relates to an extrusion forming principle and method of plastic tubes for biaxial self-reinforcement, which is characterized by realizing extruded tube forming process under a shear and tension biaxially compounded stress field, wherein the process comprises the following steps in sequence: raw material drying, extruder plasticizing, melt extruding, forming for biaxial self-reinforcement, cooling shaping and cutting and collecting. The strength and modulus of the plastic tubes produced by the method are simultaneously reinforced axially and circumferentially and the circumferential strength and modulus of the plastic tubes exceed or approach the axial strength and modulus, thus configuring the properties of the materials more optimally and better satisfying the practical demands of the tubes subject to internal pressure for the material properties. After the tubes are reinforced, the wafers of the tubes are thicker and the tubes have higher crystallinity, therefore the heat ...

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23-06-2010 дата публикации

Principle and method for forming semisolid and solid extruded axial self-enhanced plastic pipes

Номер: CN0101746042A
Принадлежит:

The invention relates to a principle and a method for producing all kinds of plastic pipe parts, in particular to a principle and a method for forming semisolid and solid extruded axial self-enhanced plastic pipes. The invention is characterized in that the pipe extruding and forming technology is realized in the environment with temperature lower than the melting point temperature of the forming material and in the axial tensile stress field capable of enabling the melted material to form tensile flow and convergent flow. The technological steps comprise drying raw materials, plasticizing through an extruder, melting and extruding, solid and semisolid axial self-enhancing and forming, cooling and setting, and cutting and collecting. The plastic pipe produced by using the method of the invention has the advantages that the strength and the modulus in the axial direction of the pipe are obviously enhanced, the performance of the material is configured in an optimizing way, and the practical ...

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30-09-2015 дата публикации

Swing arm structure for feeder

Номер: CN0204672845U
Автор: GAO XUEQIN
Принадлежит:

The utility model discloses a swing arm structure for feeder, but its including the swing arm seat, install in the length conversion slider of swing in the arm seat, install in length conversion slider upper end and free swing's follow -up slider and be used for driving length conversion slider and shift up the actuating mechanism who moves at the swing arm seat, this actuating mechanism is including installing the length adjustment lead screw in the swing arm seat, length is changed the slider and is cup jointed on the length adjustment lead screw, a tip stretches out outside the swing arm seat in the length adjustment lead screw, and installs length change gear on the tip, the length adjustment lead screw rotates through this length change gear external gear power device, this gear power device drive length adjustment lead screw, and this length adjustment lead screw drive length conversion slider shifts up in the swing arm seat and moves to realize the mesh of feed length transform.

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23-03-2018 дата публикации

Novel high efficiency beef cutting machine

Номер: CN0207127969U

The utility model discloses a novel high efficiency beef cutting machine, include the cutting bed and connect the support column in its four corners, be connected with the diaphragm between four the support column, install double -shaft motor on the diaphragm, double -shaft motor's first drive shaft is connected with first sprocket through first transfer line, and first sprocket is connected withtwo second sprockets through a chain drive, and first sprocket is triangular distribution with two second sprockets, and second sprocket coaxial coupling has a spiral shell rasp bar, and spiral shellrasp bar rotates and connects on the cutting bed top surface, and two spiral shell rasp bar are close to the cutting bed respectively and set up at both ends about, and spiral shell rasp bar goes up the cooperation and is connected with screw sleeve, just is connected with the push pedal between two screw sleeve. The utility model discloses but not only improve the efficiency of beef cutting, still reduced ...

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23-06-2010 дата публикации

Principle and method for forming semisolid and solid extruded bidirectional self-enhanced plastic pipes

Номер: CN0101746041A
Принадлежит:

The invention relates to a principle and a method for producing all kinds of plastic pipe parts and is characterized in that the semisolid and solid pipe extruding and forming technology is realized in the shear tensile bidirectional combined stress field in the environment with temperature lower than the melting point temperature of forming material. The technological steps comprise drying raw materials, plasticizing through an extruder, melting and extruding, semisolid and solid extruding, self-enhancing and forming, cooling and setting, and cutting and collecting. The plastic pipe produced by using the method of the invention has the advantages that the strength and the modulus of the pipe are obviously enhanced in both the axial direction and the circumferential direction, the performance of the material is configured in an optimizing way, and the degree of satisfaction to the practical requirements on the performance of the material of the pipe subject to internal pressure is obviously ...

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10-02-2010 дата публикации

New application of exenatide acetate and medicine aiming at new application

Номер: CN0101642561A
Принадлежит:

The invention relates to the field of pharmaceutical chemistry, in particular to a new application of exenatide acetate and medicine aiming at the new application. The new application of exenatide acetate is that the exenatide acetate is taken as a medicine used for preventing and curing diabetes and coronary disease. The invention also provides a medicine aiming at the new application. The medicine contains active constituent (exenatide acetate) of 0.005-0.4g/100ml and appropriate amount of isotonic agent. The invention has the advantages that the exenatide acetate has better curative effecton patients suffering from diseases of diabetes and coronary disease than on patients suffering from one or none of the two diseases of diabetes and coronary disease. The exenatide acetate not only relieves the symptom of diabetes of patients, but also ameliorates the function of nervi vascularis, thus facilitating the complete recovery of patients.

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08-07-2009 дата публикации

Human brain natriuretic non-competitive double-antibody sandwich method ELISA detection reagent kit

Номер: CN0101477127A
Принадлежит:

The invention discloses an ELISA testing reagent kit for a human brain natriuretic peptide noncompetitive double antibody sandwich method, which comprises a kit body, an ELIAS plate arranged in the kit body and a reagent arranged in the kit body, wherein each hole of the ELIAS plate is coated with capture antibodies, namely BNP-32 peptide monoclonal antibodies; and the reagent comprises BNP specific testing antibodies marked by horseradish peroxydase, a BNP-32 peptide series standard liquid, positive contrast blood serums, a sample diluent, a washing liquid, TMB colorimetric solutions A and B and a stop solution. The reagent kit has the advantages of low price, high efficiency, time and labor conversation, strong specificity, high sensitivity, easy popularization, and the like, can meet the requirements on clinical tests of different levels, and provide a high-efficiency reliable tool for the early discovery, early diagnosis and early treatment of cardiovascular diseases.

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18-04-2023 дата публикации

Polymer melt composite vibration extrusion molding device

Номер: CN115972533A
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The invention discloses a polymer melt composite vibration extrusion molding device which comprises a composite vibration system, the composite vibration system comprises a material passing mold, the material passing mold is formed by combining an upper mold and a lower mold, and the parting surface of the material passing mold is provided with a runner which penetrates through the two ends of the material passing mold and allows the polymer melt to circulate; the upper die is provided with at least one first through hole, and the lower die is provided with at least one second through hole; the first through hole and the second through hole are respectively perpendicular to and communicated with the runner; the low and medium frequency vibration module comprises a vibration rod which is mounted in the first through hole and extends into the flow channel, and a driving piece drives the vibration rod to do piston motion in the first through hole; the high-frequency ultrasonic module comprises ...

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20-05-2009 дата публикации

Chinese medicine prepared aconite root and method for establishing fingerprint of alkaloid in extract thereof

Номер: CN0101433604A
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The invention relates to a method for establishing fingerprint of alkaloid in traditional Chinese medicine aconite or extract thereof. The method adopts an opposite phase high performance liquid chromatography, uses octadecylsilane chemically bonded silica or octadsilane chemically bonded silica as a filling agent, and uses an organic phase-buffer solution as a mobile phase, wherein pH value of the organic phase-buffer solution is 3.0 to 8.0, detection wavelength is 230 to 240 nanometers, the organic phase accounts for 20 to 70 percent of volume percentage of the mobile phase, and the organic phase is acetonitrile or methanol; the buffer solution is one of ammonium acetate-acetic acid buffer solution, triethylamine-acetic acid buffer solution, triethylamine-ammonium acetate-acetic acid buffer solution and triethylamine-acetic acid ammonium-acetic acid buffer solution; and the method comprises the following steps: using proper amount of aconitine, mesaconine or hypaconitine to prepare reference ...

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23-06-2010 дата публикации

Extrusion forming principle and method of plastic tubes for circumferential self-reinforcement

Номер: CN0101746048A
Принадлежит:

The invention relates to an extrusion forming principle and method of plastic tubes for circumferential self-reinforcement, which is characterized by realizing extruded tube forming process under a circumferential shear stress field, wherein the process comprises the following steps in sequence: raw material drying, extruder plasticizing, melt extruding, forming for circumferential self-reinforcement, cooling shaping and cutting and collecting. The strength and modulus of the plastic tubes produced by the method are simultaneously reinforced circumferentially and exceed or approach the axial strength and modulus, thus configuring the properties of the materials more optimally and better satisfying the practical demands of the tubes subject to internal pressure for the material properties. After the tubes are reinforced, the wafers of the tubes are thicker and the tubes have higher crystallinity, therefore the heat resistance of the tubes is obviously improved compared with the conventional ...

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23-06-2010 дата публикации

Low-temperature near-melting point extrusion molding principle and method for circumferential self-reinforced plastic pipe

Номер: CN0101746047A
Принадлежит:

The invention relates to a low-temperature near-melting point extrusion molding principle and a low-temperature near-melting point extrusion molding method for a circumferential self-reinforced plastic pipe, which are characterized in that: an extrusion molding process is implemented under an axial shear stress field in a temperature environment of which the temperature is slightly higher than the melting point of the molded material. The method comprises the following processing steps: drying raw materials, plastifying the raw materials by using an extruder, extruding melt, low-temperature near-melting point circumferential self-reinforced molding, cooling and shaping, and cutting and collecting. The strength and modulus of the plastic pipe produced by the method are both reinforced in the circumferential direction, and can exceed or be close to those of the pipe in the axial direction, so that the material performance is optimally configured, and the actual requirements of pipes subjected ...

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16-07-2008 дата публикации

Hydrochloric acid glitazone dispersion piece and its preparation method

Номер: CN0101219122A
Принадлежит:

The invention relates to a pioglitazone hydrochloride tablet and a preparation method thereof. The pioglitazone hydrochloride tablet comprises a pioglitazone, a diluting agent, a disintegrating agent, a bonding agent, a lubricant and other auxiliary agents, wherein, the diluting agent includes one or more components selected from lactose, amylum pregelatinisatum and microcrystalline cellulose; the disintegrating agent includes one component selected from cross-linked polyvinyl pyrrolidone and microcrystalline cellulose or the combination thereof; the bonding agent comprises amylum pregelatinisatum and water or ethanol liquor of hydroxypropyl methyl cellulose; the lubricant comprises magnesium stearate. The preparation method comprises that (in sequence): the pioglitazone hydrochloride and the auxiliary materials thereof are weighed and screened according to a prescription; the diluting agent, other auxiliary agents and part of the disintegrating agent are mixed to obtain a powder mixture ...

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