05-04-2018 дата публикации
Номер: US20180092940A1
Принадлежит:
Compositions are described that contain treated chitosan, modified chitosan and/or modified and treated chitosan for use in formulations for skin, hair and nails, and in compositions and methods of reducing topical agent-induced skin irritation and inflammation. 1. A composition comprising: (a) at least one topical irritating agent that causes skin irritation and/or IL-1α secretion , and (b) at least one chitosan covalently modified with an alkyl sulfonic acid via a sulfonamide linkage.2. The composition of claim 1 , wherein the at least one topical irritating agent comprises at least one cosmetic agent claim 1 , therapeutic agent claim 1 , cleansing agent claim 1 , detergent claim 1 , disinfectant claim 1 , antiseptic claim 1 , antimicrobial agent claim 1 , anti-fungal agent claim 1 , anti-parasitic agent claim 1 , anti-bacterial agent claim 1 , anti-viral agent claim 1 , solvent claim 1 , fragrance claim 1 , dye claim 1 , adhesive claim 1 , paint remover claim 1 , preservative claim 1 , sterilizing agent claim 1 , transdermal-delivery agent claim 1 , transdermal delivery device claim 1 , mineral claim 1 , or a composition or a combination of two or more thereof.3. The composition of claim 2 , wherein the at least one cosmetic or therapeutic agent comprises an anti-aging agent claim 2 , lightening agent claim 2 , darkening agent claim 2 , beautifying agent claim 2 , retinoid claim 2 , retinoid derivative claim 2 , retinoid precursor claim 2 , retinoid active metabolite claim 2 , acne therapeutic agent claim 2 , rosacea therapeutic agent claim 2 , actinic keratosis therapeutic agent claim 2 , anti-inflammatory agent claim 2 , anti-bacterial agent claim 2 , anti-fungal agent claim 2 , anti-viral agent claim 2 , anti-parasitic agent claim 2 , anti-wart agent claim 2 , or a composition or a combination of two or more thereof.4. The composition of claim 1 , wherein the at least one topical irritating agent comprises an insecticide.5. The composition of claim 1 , wherein ...
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