Self-adaptive control skin surface electrical stimulation device and method

The invention discloses a self-adaptive control skin surface electrical stimulation device, which uses a stimulation electrode to act on skin surfaces. The device is characterized by comprising a voltage regulating circuit, an electric pulse generation circuit, a stimulation electrode, a current measuring circuit and a skin resistance calculating unit, wherein a human body is stimulated by manually regulating the initial voltage value of the stimulation circuit; the current measuring circuit detects a current input into the human body; the current voltage and current are used to calculate the resistance of the skin; the voltage is regulated according to the relationship between feeling and a stimulation strength, so that the feeling of a person can keep constant. Compared with the prior art, the system has the advantages that: as a body surface electrical stimulation mode is adopted, when the device is used, an electrical stimulation electrode is contacted with the body surface, namely ...

Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine

GINKGO BILOBA LEAVE EXTRACT CAPSULE AND PREPARATION METHOD THEREFOR

The present disclosure provides a ginkgo biloba ketone ester capsule. The present disclosure further provides a method for preparing ginkgo biloba ketone ester capsule and use thereof. The present disclosure provides a ginkgo biloba ketone ester capsule and a preparation method thereof. Through optimized preparation operations and conditions, a high-quality ginkgo biloba ketone ester capsule can be obtained. Compared with the ginkgo biloba ketone ester capsule prepared by traditional methods, the ginkgo biloba ketone ester capsule of the present disclosure has stable quality and a low unqualified rate. The consistency of different batches of ginkgo biloba ketone ester capsules is good. In particular, the ginkgo biloba ketone ester capsule can effectively control ginkgolic acids, preventing the use of high-ginkgolic-acid raw materials in the ginkgo biloba ketone ester capsules, so as to effectively improve the safety of ginkgo biloba ketone ester capsules. 1. A ginkgo biloba ketone ester capsule , prepared by mixing ginkgo biloba ketone ester raw materials and excipients , granulating and filling into capsules , wherein the ginkgo biloba ketone ester capsule , based on a loading weight of each capsule being 0.2 g , meets the following conditions:1) a content of rutin is less than or equal to 1.60 mg/capsule;2) a content of quercetin is less than or equal to 0.160 mg/capsule.3) a content of bilobalide is 1.04-2.08 mg/capsule;4) a content of ginkgolide J is 0.04-0.20 mg/capsule;5) a residual content of ethanol is less than or equal to 0.2 mg/capsule;6) a content of biflavonoids is less than or equal to 0.008 mg/capsule, the biflavonoids include Amentoflavone, Bilobetin, and Ginkgetin; and7) a content of Genistin is 0, and a content of ginkgolide M is 0.2. The ginkgo biloba ketone ester capsule according to claim 1 , wherein a content of total flavonoids in the ginkgo biloba ketone ester capsule is 14.08-26.40 mg/capsule calculated as rutin; a content of terpene ...

Mono-lysine salts of azole compounds

Crystalline form of methyl ((1s)-1-(((2s)-2-(5-(4'-(2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt

Extract of ginkgo biloba leaves and dipyridamole composite and preparation method and application thereof

The invention relates to an extract of ginkgo biloba leaves and dipyridamole composite with platetet inhibition function and a preparation method and an application thereof; the composite comprises extract of ginkgo biloba leaves and dipyridamole in a weight ratio of 1-10:1, wherein, extract of ginkgo biloba leaves comprises 60-78% of ginkgo flavone, 2.5-10% of ginkgolides, 2.5-10% of bilobalide and 0.1-5ppm of ginkgoic acid; ginkgolides comprise ginkgolide A, B, C and J. the ginkgo biloba leaves and dipyridamole composite of the invention has higher curative effect for platetet inhibition and dilating coronary artery and less adverse reaction compared with common ginkgo leaf extract and dipyridamole preparation.

消旋和光活胡桐素A及其类似物的制备方法

The present invention discloses the preparation process of racemized and optically active Calanolide A and its analog 11-norcalnolide A.

Intermediate of flavonoid compound and preparation method and application thereof

The invention discloses an intermediate of a flavonoid compound shown in a formula K and a preparation method thereof. In the heterogeneous solution of a non-protonic solvent and water, under the action of an alkaline reagent and a phase transfer catalyst, the compound shown in the formula L reacts with 2,3,4,6-tetraphenyl formyloxy bromo-glucose shown in the formula H, wherein R1 is -CO(CH2)nCH3 or benzoyl; n ranges from 0 to 8; and Bz is the benzoyl. The invention also relates to application of the intermediate of the flavonoid compound shown in the formula K in preparation of the flavonoid compound shown in the formula A. Compared with the conventional method for separating and extracting the flavonoid compound shown in the formula A from the plant, the method for preparing the flavonoid compound shown in the formula A from the intermediate of the flavonoid compound shown in the formula K can realize large-scale industrialized production, and has the advantages of simple steps, no special ...

Intermediate of flavonoid compound and preparation method and application thereof

The invention discloses an intermediate of a flavonoid compound shown in a formula J and a preparation method thereof. In the mixed solvents of a non-protonic solvent and an alcohol solvent, under the action of an alkaline reagent, the compound shown in the formula K undergoes selective dehydroxylation protecting group reaction, wherein R1 is -CO(CH2)nCH3 or benzoyl; n ranges from 0 to 8; and Bz is the benzoyl. The invention also relates to application of the intermediate of the flavonoid compound shown in the formula J in preparation of the flavonoid compound shown in the formula A. Comparedwith the conventional method for separating and extracting the flavonoid compound shown in the formula A from the plant, the method for preparing the flavonoid compound shown in the formula A from the intermediate of the flavonoid compound shown in the formula J can realize large-scale industrialized production, and has the advantages of simple steps, no special reagent or harsh requirements on reaction ...

Mono-lysine salts of azole compounds

Mono-lysine salts of triazole compounds having a secondary or tertiary hydroxy group are provided. More particularly, the new water-soluble triazole antifungal mono-lysine salt compounds, or solvates thereof, are provided having the general formula I: wherein A in formula I represents the non-hydroxy portion of a triazole antifungal compound of the type containing a secondary or tertiary hydroxyl group. R and R1 in formula I can each be a hydrogen atom or an alkyl group having one to six carbon atoms. The novel water-soluble azole compounds are useful for the treatment of fungal infections and can be administered orally, topically and parenterally.

Intermediate of flavonoid compound and preparation method and application thereof

The invention discloses an intermediate of a flavonoid compound shown in a formula E and a preparation method thereof. In the mixed solvents of a non-protonic solvent and an alcohol solvent, under the action of an alkaline reagent, the compound shown in the formula F undergoes selective dehydroxylation protecting group reaction, wherein R1 is -CO(CH2)nCH3 or benzoyl; n ranges from 0 to 8; and Bn is the benzyl. The invention also relates to application of the intermediate of the flavonoid compound shown in the formula E in preparation of the flavonoid compound shown in the formula A. Compared with the conventional method for separating and extracting the flavonoid compound shown in the formula A from the plant, the method for preparing the flavonoid compound shown in the formula A from the intermediate of the flavonoid compound shown in the formula E can realize large-scale industrialized production, and has the advantages of simple steps, no special reagent or harsh requirements on reaction ...

Running method of urban ground public transport

The invention discloses a running method of urban ground public transport, which adopts the technical scheme that: the present A-N station platform mode of the urban public transport is improved to a network station-free mode. One straight road and one bus are arranged on the criss-cross trunk, a long route line is segmented and overlapped, and the density can be adjusted, so passengers can go on bus only by waving hands and can take off the bus by speaking in advance. The bus is designed into a mode with two ends being provided with a cab. When at the crossing of red light or in road blockage for other reasons as well as the segmentation terminal, the bus is free from turning around for going back (bus cannot be blocked), and the passengers can take off the bus (walking is faster than the bus) to avoid the blocking point and to transfer other buses which are not blocked.

Composition from ginkgo biloba leaves, preparation and uses

Method for preparing flavonoid compound and used medium thereof

The invention discloses a method for preparing a flavonoid compound shown as a formula B, which comprises the following steps: dissolving a compound shown as a formula E in non-protonic solvent, dropwise adding the solution into the alcoholic solution of sodium alkoxide to react, and thus preparing the compound shown as a formula B, wherein R is-O(CH2)n'CH3 or benzoyl, and n' is equal to 0 to 6. The invention also discloses a novel medium compound shown as E and F, wherein R is-CO(CH2)4CH3.

Preparation method of biological lube base oil and preparation device thereof

The invention discloses a preparation method of biological lube base oil and a preparation device thereof. The method comprises the following steps: firstly, liquid low carbon alcohol is input to a carburetor for vaporization and is heated up to reaction temperature; the vaporized low carbon alcohol is input to a guide shell via a distributor, gas phase low carbon alcohol is mixed with reaction solutions in a reaction kettle and is shattered and boosted by a stirrer and the mixed liquid flows circularly and reacts continuously to generate base oil which is discharged from the bottom of the reaction kettle. The preparation device comprises the reaction kettle, a low carbon alcohol feeding device connected with the reaction kettle and a low carbon alcohol carburetor arranged between the reaction kettle and the low carbon alcohol feeding device. The guide shell inside the reaction kettle is provided with the distributor for evenly spraying low carbon alcohol into an internal cavity of the ...

Construction method of primary oil long-distance pipeline electric heating membrane safety heating system

Composition from ginkgo biloba leaves, preparation and uses

Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorohphenyl)- 1,2,3,4-tetrahydroisoquinoline and use thereof

Novel [1,2,4]triazolo[1,5-]pyridinyl-6-yl-substituted tetrahydroisoquinolines are described in the present invention. These compounds and crystalline forms SA1 and N-2 are used in the treatment of various neurological and physiological disorders. Methods of making these compounds and crystalline forms SA-1 and N-2 are also described in the present invention.

Titanium alloy with thin sheet layer microstructure and manufacturing method thereof

The invention provides a titanium alloy with a thin sheet layer microstructure and a manufacturing method thereof. The titanium alloy is characterized in that: 1) a certain amount of Si element is added into the alloy so that Ti5Si3 or Ti2Si type silicide can be dissolved out from the alloy under a certain condition; 2) controlling the adding amount of alloying elements, namely Zr, Sn and beta stable elements, which affect the dissolving temperature of the silicide so as to guarantee that the alpha + beta/beta transformation temperature of the titanium alloy is lower than the dissolving temperature of the silicide; 3) fully deforming the alloy at the temperature of below the dissolving temperature of the silicide, and finally properly deforming the alloy in the alpha + beta phase area over 1 to 2 fire, wherein the primary beta crystallite dimension of the alloy after thermal treatment is less than 200 mu m and the alloy has a thin sheet lamellar structure. The invention also provides a ...

Jet-extrusion type washing machine

The utility model relates to a jet-extrusion type washing machine. The utility model is provided with a machine casing; a water tank is arranged below the machine casing, and the inner part of the machine casing is provided with a water receiving bucket. A drainage pipe on the bottom of the water receiving bucket is communicated with the water tank through a drainage electromagnetic valve. A washing drum is sheathed in the water receiving bucket. The bottom of a washing box is connected with a rotary driving device. The inner part of the washing drum is provided with a water jetting pipe, and the input end of the jetting pipe is communicated with a water inlet pipe and the water tank through a water pump. The utility model adopts the method of the combining water jetting and cloth rotary extrusion, so the utility model has the advantages of small damage to washed clothes, high cleanness degree and water saving.

Crystalline form of 6-[(4s)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine

The present disclosure generally relates to a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. The present disclosure also generally relates to pharmaceutical compositions comprising the crystalline form, as well of methods of using a crystalline form in the treatment of depression and other conditions and methods for obtaining such crystalline form.

MONO-LYSINE SALTS OF AZOLE COMPOUNDS

Method for preparing dimer acid and dimer acid methyl ester

The invention relates to an improvement of a method for preparing dimer acid and dimer acid methyl ester by using unsaturated fatty acid and corresponding fatty acid methyl ester thereof, which is characterized in that a catalyst for reaction is sulfonate ionic liquid which contains SO3H functional groups and accounts for not less than 0.5% in parts by weight, the reaction is carried out at the temperature of 150-300 DEG C, the iodine value of products are controlled to be 65-80%, and the products and the catalyst are stratified by standing after the reaction is complete. The method has the advantages of high polymerization reaction activity, fast reaction speed and relatively mild reaction conditions, and the reaction can be carried out at atmospheric pressure and relatively low temperature, thereby not only reducing the reaction energy consumption and having low requirements on equipment, but also greatly reducing the preparation cost. The catalyst has good stability and small usingquantity ...

Schistosoma japonicum 23kDa membrane protein big hydrophilic peptide segment fusion protein and application thereof in schistosome infection immune diagnosis

The invention relates to schistosoma japonicum 23kDa membrane protein big hydrophilic peptide segment fusion protein and application thereof in schistosome infection immune diagnosis and belongs to the technical field of immunological diagnosis of parasitic diseases. The invention relates to fusion protein of schistosoma japonicum 23kDa membrane protein big hydrophilic peptide segment (Sj23HD) and human serum albumin (HAS). The fusion protein comprises two polypeptide regions, wherein the first region is the Sj23HD; the second region is the HAS; the C tail end of the first region is directly connected with the N tail end of the second region without any connecting peptide; and the structural formula is Sj23HD-HAS. The Sj23HD-HAS fusion protein remains the reactogenicity of the Sj23HD and has higher stability. The Sj23HD-HAS fusion protein, serving as a detecting antigen to diagnose the schistosome infection by the Western blot, has higher sensitivity and specificity.

Method for preparing flavonoid dimeric compound as well as medium and preparation method thereof

The invention discloses a compounding method for preparing a flavonoid dimeric compound of formula D. In the mixed solvent of non-protonic solvent and alcoholic solvent, under the action of catalytic hydrogenation reaction catalyst, the compound of formula A is debenzylated by catalytic hydrogenation reaction, and the flavonoid dimeric compound of formula D can be prepared, wherein n is equal to 1 to 9, and Bn is the phenmethyl. The invention also discloses a novel medium compound A used for the method and a preparation method thereof. Compared with the prior method for synthesizin the flavonoid dimeric compound sof formula D, the method has the advantages of simpler operation, shorter route and higher yield.

Method for preparing flavonoid compound and used intermediate thereof

The invention discloses a method for preparing a flavonoid compound shown as a formula B, which comprises the following steps: dissolving a compound shown as a formula E in non-protonic solvent, dropwise adding the solution into the alcoholic solution of sodium alkoxide to react, and thus preparing the compound shown as a formula B, wherein R is-O(CH2)n'CH3 or benzoyl, and n' is equal to 0 to 6. The invention also discloses a novel intermediate compound shown as E and F, wherein R is-CO(CH2)4CH3.

Method for preparing flavonoid compounds, used intermediate and preparation method thereof

The invention discloses a method for preparing flavonoid compounds shown in formula A, which comprises the following step: performing dehydroxylation protecting group reaction of the compounds shown in a formula B in a mixed solvent of a non-protonic solvent and an alcohol solvent under the action of an alkaline reagent to form the flavonoid compounds shown in the formula A, wherein R1 is -CO (CH2)n CH3 or benzoyl, n is 0 to 8, and Bz is benzoyl. The invention also relates to a new intermediate compound shown in the formula B and a preparation method thereof. Compared with the conventional method for extracting the flavonoid compounds shown in the formula A by separating from plants, the synthesis method of the invention makes the large-scale industrialized production of the compounds become possible; and the method of the invention has simple steps, has no strict requirements on a special reagent and reaction conditions, and has higher yield and purity.

Fusion protein of insulin secretion accelerating peptide and human serum albumin, and preparation method thereof

A fusion protein for insulinotropic hormone secretion peptide and human blood serum albumin, and preparation thereof, which pertains to long-acting recombinant fusion protein technical field. The invention relates to fusion protein for insulinotropic hormone secretion peptide (Exendin-4) and human blood serum albumin (HSA), which contains two polypeptide area, wherein the first area comprises a plurality of insulinotropic hormone secretion peptide Exendin-4 repeats, the second area comprises human blood serum albumin HSA. The first area is directly connected to N-terminal of the second area through C-terminal thereof, without any connecting peptide therebetween. The formula is: (Exendin-4)n-HSA, wherein n is repeat times of Exendin-4 repeats, which is 2-8. Application of the (Exendin-4)n-HSA fusion protein can stabilize blood glucose level of mammals, so that it can be used in preparation of remedies for non-insulin-dependent diabetes mellitus and obesity, which has higher stability and ...

Method and device for modulating electromagnetic stirring and rotating magnetic field based on permanent magnet

The invention relates to a method and a device for modulating an electromagnetic stirring and rotating magnetic field based on a permanent magnet. In the method, a magnetic field the magnetic induction of which changes in accordance with the following equation of B=B0cos(2*pi*omega*t+phi) can be generated, wherein the magnetic field amplitude B0, the magnetic field frequency omega and the magnetic field phase position phi can be modulated independently or jointly. The device adopts the magnetic field modulation method and structurally comprises a stirrer wrapped on the periphery of a crystallizer, and the internal structure thereof is characterized in that a permanent magnet is inlaid in a toroidal core; the toroidal core is connected with a programmable stepping motor and is driven by the stepping motor to rotate; and the magnetic field generated by the stirrer always keeps the same rotating mode with the stepping motor. The invention can modulate the amplitude, the frequency and the phase ...

Mono-lysine salts of azole compounds

Mono-lysine salts of triazole compounds having a secondary or tertiary hydroxy group are provided. More particularly, the new water-soluble triazole antifungal mono-lysine salt compounds, or solvates thereof, are provided having the general formula I: wherein A in formula I represents the non-hydroxy portion of a triazole antifungal compound of the type containing a secondary or tertiary hydroxylgroup. R and R1 in formula I can each be a hydrogen atom or an alkyl group having one to six carbon atoms. The novel water-soluble azole compounds are useful for the treatment of fungal infections and can be administered orally, topically and parenterally.

EXTRACT OF GINKGO BILOBA LEAVES AND PREPARATION METHOD THEREFOR

The present disclosure provides a Ginkgo biloba ketone ester bulk drug. The present disclosure further provides a method for preparing Ginkgo biloba ketone ester bulk drug and use thereof. The present disclosure provides a Ginkgo biloba ketone ester and a preparation method thereof. Through optimized preparation operations and conditions, high-quality Ginkgo biloba ketone ester bulk drug can be obtained. Compared with the Ginkgo biloba ketone ester prepared by traditional methods, the Ginkgo biloba ketone ester of the present disclosure has stable quality, low unqualified rate, and good consistency of different batches of bulk drugs.

Method for designing guide roller of slab caster

The invention relates to a method for designing a guide roller of a slab caster, which is characterized in that the guide roller comprises a rotating joint, a central spindle and roll sleeves, wherein 3 to 9 through water holes are processed in the roll sleeve, two radial through water holes are processed at the two ends of the central spindle corresponding to the roll sleeves, a through water ring is arranged between the roll sleeves and the central spindle, and a seal ring is used for sealing a water route; cooling water feeds in the central spindle from the rotating joint, then enters the roll sleeve from the radial water holes on the central spindle, after performed with circulation cooling in the radial water holes of the roll sleeve, the cooling water flows back to a central hole of the central spindle from the other radial water hole in the central spindle, then enters the other roll sleeve to carry out cooling so as to achieve the purpose of completely cooling the central spindle ...

Card type wideband access management system

The invention relates to a card-type broadband network access management system, comprising: a card-reading terminal for authenticating a user terminal accessing the broadband network, reporting timing information of the card-reading terminal to a user terminal and working state information of the card-reading terminal after the authentication is passed; network management modules for receiving the timing information and working state information reported by the card-reading terminal, receiving clock information that checks clocks of each card-reading terminal; a network management server for receiving the timing information and working state information transmitted by the network management module in fixed time, uniformly managing and maintaining the received information, and transmitting unified clock information to each network management module. The card-type broadband network access management system provided by the invention is capable of manage and maintain a card-type broadband ...

Chinese medicine preparation for treating respiratory tract infection and virus flu, preparing method thereof

Forma cristalina de la sal diclorhidrato de ((1s)-1-(((2s)-2-(5-(4'-(2-((2s)-1-((2s)-2-((metoxicarbonil)amino)-3-metilbutanoil)-2-pirrolidinil)-1h-imidazol-5-il)-4-bifenilil)-1h-imidazol-2-il)-1-pirrolidinil)carbonil)-2-metilpropil)carbamato de metilo; composición y combinacion farmacéutica; y su uso para tratar la hepatitis c.

LA PRESENTE REVELACIÓN SE REFIERE, EN GENERAL A UNA FORMA CRISTALINA DE SAL DICLORHIDRATO DE ((15)-1-((25)-2-(5-(4'-(2-( (25)-1-((25)-2-( (METOXICARBONIL)AMINO)-3-METILBUTANOIL)-2- PI RROLIDI NI1)-LH- IMIDAZOL- S-I 1) -4-BIFEN ILI 1)-LH- IMIDAZOL-2-I 1) -L-PI RROL ID INI I)CARBON I1)-2-METIIPROPIL) CARBAMATO DE METILO. LA PRESENTE REVELACIÓN SE REFIERE TAMBIÉN, EN GENERAL, A UNA COMPOSICIÓN FARMACÉUTICA QUE COMPRENDE UNA FORMA CRISTALINA, ASÍ COMO A PROCEDIMIENTOS DE USO DE UNA FORMA CRISTALINA EN EL TRATAMIENTO DE HEPATITIS.

Method for detecting and identifying plasmodium sperozoites in mosquito medium

The invention discloses a method for detecting and identifying plasmodium sperozoites in a mosquito medium. The method comprises the following steps of: 1) designing a pair of primers; 2) extracting a plasmodium sperozoite genome deoxyribonucleic acid (DNA) in anopheles serving as a medium; 3) performing amplification on the plasmodium sperozoite genome DNA in the mosquito medium by a fluorescent quantitative polymerase chain reaction (PCR); and 4) melting an amplification product to obtain a melting curve, and comparing with positive control and negative control. The method has the advantages that: through the method for detecting and identifying plasmodium sperozoites in the mosquito medium and application thereof, plasmodia in the mosquito medium can be quantitatively detected, and can be qualitatively identified according to plasmid DNA standard substances of four constructed human plasmodia (which are shown as the figure 2), the sensibility and specificity of the detection and identification ...

Fusion protein of insulin secretion accelerating peptide and human serum albumin, and preparation method thereof

The present invention relates to a fusion protein for insulinotropic hormone secretion peptide and human blood serum albumin, and preparation thereof, belonging to the long-acting recombinant fusion protein technical field. The invention relates to fusion protein for insulinotropic hormone secretion peptide (Exendin-4) and human blood serum albumin (HSA), which contains two polypeptide area, wherein the first area comprises a plurality of insulinotropic hormone secretion peptide Exendin-4 repeats, the second area comprises human blood serum albumin HSA. The first area is directly connected to N-terminal of the second area through C-terminal thereof, without any connecting peptide therebetween. The formula is: (Exendin-4)n-HSA, wherein n is repeat times of Exendin-4 repeats, which is 2-8. Application of the (Exendin-4)n-HSA fusion protein can stabilize blood glucose level of mammals, so that it can be used in preparation of remedies for non-insulin-dependent diabetes mellitus and obesity ...

Extra-cellular polysaccharide of aerobic Ruthia sp. strain metabolin and preparation and application thereof

The invention relates to an extra-cellular polysaccharide of aerobic Ruthia sp. strain metabolin and preparation and application thereof. An aerobic strain ZHT4-13 is separated from adhesive sludge of wild Ruditapes philippinarums in the Bohai sea offshore of China and is identified as a Ruthia sp. The aerobic strain is treated by seed culture and amplification culture, and a fermentation broth of the aerobic strain is precipitated with ethanol and separated centrifugally to obtain the extra-cellular polysaccharide MBF4-13. The extra-cellular polysaccharide MBF4-13 is measured to have high flocculation activity, the FR value to kaolin reaches over 80 percent, and the removal rate to hexavalent chromium ions reaches 69.3 percent; the extra-cellular polysaccharide MBF4-13 has high activity to decolorize high-concentration wastewater, and the decolorization ratios to methylene blue, ink blue, malachite green and crystal violet reach 86.11 percent, 99.49 percent and 97.84 percent; and the extra-cellular ...

Card type broadband network access system and method

The invention relates to a card type broadband network access system and a method thereof. The system comprises a card reading terminal for authenticating subscriber terminals accessing the broadband network and forwarding DHCP requests of the subscriber terminals and IP addresses distributed to the subscriber terminals; a two-layer switch for forwarding the DHCP requests of the subscriber terminals and the IP addresses distributed to the subscriber terminals, and for uploading / downloading data information desired by the subscribers; a three-layer switch for distributing IP addresses to the subscriber terminals. The method comprises steps of the carding reading terminal authenticating subscriber terminals accessing the broadband network, receiving the DHCP requests of the subscriber terminals after the authentication is passed; the two-layer switch receiving the DHCP requests forwarded by the two-layer switch and sending them to the three-layer switch; the three-layer switch distributing ...

Use of ginkgoic acid in preparation of biological pesticide for killing Oncomelania snail and preventing schistosomiasis

Intermediate of flavonoid compound and preparation method and application thereof

The invention discloses an intermediate of a flavonoid compound shown in a formula K and a preparation method thereof. In the heterogeneous solution of a non-protonic solvent and water, under the action of an alkaline reagent and a phase transfer catalyst, the compound shown in the formula L reacts with 2,3,4,6-tetraphenyl formyloxy bromo-glucose shown in the formula H, wherein R1 is -CO(CH2)nCH3or benzoyl; n ranges from 0 to 8; and Bz is the benzoyl. The invention also relates to application of the intermediate of the flavonoid compound shown in the formula K in preparation of the flavonoidcompound shown in the formula A. Compared with the conventional method for separating and extracting the flavonoid compound shown in the formula A from the plant, the method for preparing the flavonoid compound shown in the formula A from the intermediate of the flavonoid compound shown in the formula K can realize large-scale industrialized production, and has the advantages of simple steps, no special ...

Method for preparing flavonoid dimeric compound as well as medium and preparation method thereof

The invention discloses a compounding method for preparing a flavonoid dimeric compound of formula D. In the mixed solvent of non-protonic solvent and alcoholic solvent, under the action of catalytic hydrogenation reaction catalyst, the compound of formula A is debenzylated by catalytic hydrogenation reaction, and the flavonoid dimeric compound of formula D can be prepared, wherein n is equal to1 to 9, and Bn is the phenmethyl. The invention also discloses a novel medium compound A used for the method and a preparation method thereof. Compared with the prior method for synthesizin the flavonoid dimeric compound sof formula D, the method has the advantages of simpler operation, shorter route and higher yield.

Crystalline form of methyl ((1s)-1-(((2s)-2-(5-(4'-(2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1h-imidazol-5-yl)-4-biphenylyl)-1h-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt

The present disclosure generally relates to a crystalline form of methyl ((1S)-1-(((2S>2-(5-(4'-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)- 1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt. The present disclosure also generally relates to a pharmaceutical composition comprising a crystalline form, as well of methods of using a crystalline form in the treatment of Hepatitis C and methods for obtaining such crystalline form.

Schistosome infectious oncomelania detection kit and detection method thereof

A blood fluke infectious oncomelania detection kit and a detection method thereof belongs to the verminosis transmission medium detecting field. The invention provides a kit and a detection method for detecting blood fluke infectious oncomelania based on a loop-mediated isothermal DNA amplification technology (LAMP). According to the LAMP technology principle, six pairs of specific primers for amplifying a DNA fragment between the 20bp and 231bp of the schistosoma japonicum non-long terminal repeated inverse transcription transposon gene (AF412214) are designed. The LAMP method is constructed for detecting blood fluke gene in the body of the infectious oncomelania and the objective for distinguishing the blood fluke infectious oncomelania from the non-infectious oncomelania is reached. Comparing to the conventional blood fluke infectious oncomelania detection method the method of the invention has advantages of easy and fast operation, sensitive and specific without especial equipment and ...

Ginkgo flavone internal ester extract and preparation process thereof

Infrared phase-changing material and preparation method thereof

The invention relates to an infrared phase-changing material, which relates to an optoelectronic material. The infrared phase-changing material comprises an inner shell, an outer shell, and a core material, the inner shell comprises a copolymer containing styrene and methylacrylic acid, the outer shell comprises conductive polyaniline, and the core material comprises various kinds of paraffins. The preparation method comprises the following steps: uniformly mixing the paraffins, styrene, methylacrylic acid, dodecyl mercaptan and azobisisobutyronitrile according to a certain proportion; dissolving a certain amount of sodium dodecyl sulfate and TritonX-100 in de-ionized water; completely mixing the two solutions together, moving the solutions in a four-hole bottle after ultrasonic emulsification in ice-bath, filling nitrogen, heating and agitating; after six hours, obtaining a powder sample through cooling, emulsion breaking, filtration, washing and drying; uniformly mixing a certain proportion ...

Novel security inspection door

The invention belongs to the technical field of detection and in particular discloses a novel security inspection door. In the security inspection door, a radioactive detection system is arranged in a metal detection system, wherein a radioactive detector is arranged in a small coil or arranged between a big coil and the small coil and outside the magnetic lines between the big coil and the smallcoil or arranged between the big coil and the small coil and coated with a screening layer. The security inspection door smartly solves the problem of the interference of the radioactive detection system with and realizes the integration of the metal detection and radioactive detection of the security inspection door.

Method for preparing flavonoid compounds, used intermediate and preparation method thereof

The invention discloses a method for preparing flavonoid compounds shown in formula A, which comprises the following step: performing dehydroxylation protecting group reaction of the compounds shown in a formula B in a mixed solvent of a non-protonic solvent and an alcohol solvent under the action of an alkaline reagent to form the flavonoid compounds shown in the formula A, wherein R1 is -CO (CH2)n CH3 or benzoyl, n is 0 to 8, and Bz is benzoyl. The invention also relates to a new intermediate compound shown in the formula B and a preparation method thereof. Compared with the conventional method for extracting the flavonoid compounds shown in the formula A by separating from plants, the synthesis method of the invention makes the large-scale industrialized production of the compounds become possible; and the method of the invention has simple steps, has no strict requirements on a special reagent and reaction conditions, and has higher yield and purity.

Method for improving bioactivity of exendin fusion protein

The invention discloses a method for improving the bioactivity of an exendin fusion protein, which belongs to the technical field of biopharmaceuticals. In the method, an Exendin-4 and GLP-1 are connected in series first and then are connected with human serum albumin HSA or human immunoglobulin Fc to form the fusion protein, so as to increase the bioactivity of the exendin fusion protein. The fusion protein is expressed as: (Exendin-4-GLP-1)n-HSA, (GLP-1-Exendin-4)n-HSA, (Exendin-4-GLP-1)n-Fc or (GLP-1-Exendin-1)n-Fc, wherein the value of n ranges from 1 to 5. The fusion protein prepared by the method has higher bioactivity than a fusion protein Exendin-4-HSA or a GLP-1-HSA protein. The fusion protein of the invention can be used for preparing medicaments for treating non-insulin-dependent diabetes, various symptoms of the non-insulin-dependent diabetes and obesity.

Infrared phase-changing material and preparation method thereof

The invention relates to an infrared phase-changing material, which relates to an optoelectronic material. The infrared phase-changing material comprises an inner shell, an outer shell, and a core material, the inner shell comprises a copolymer containing styrene and methylacrylic acid, the outer shell comprises conductive polyaniline, and the core material comprises various kinds of paraffins. The preparation method comprises the following steps: uniformly mixing the paraffins, styrene, methylacrylic acid, dodecyl mercaptan and azobisisobutyronitrile according to a certain proportion; dissolving a certain amount of sodium dodecyl sulfate and TritonX-100 in de-ionized water; completely mixing the two solutions together, moving the solutions in a four-hole bottle after ultrasonic emulsification in ice-bath, filling nitrogen, heating and agitating; after six hours, obtaining a powder sample through cooling, emulsion breaking, filtration, washing and drying; uniformly mixing a certain proportion ...

Display driver system and method for driving displays

Elevator power generation

The invention discloses a power generation device of an 'elevator'. In the prior elevator, going upstairs and downstairs needs electricity. The invention is as follows: when the elevator loads downstairs, the elevator needs to generate power. Therefore, a high-rise is built; a ladder-type exhibition hall is arranged; a three-dimensional walking street is built; and a customer goes to the high-rise while shopping unconsciously. A parking lot is arranged on the high-rise; if the customer needs to park, the customer can drive along a spiral type track and go upstairs for parking. The customer and an automobile are guided to the high-rise; the customer and the automobile can go downstairs by the elevator, which is similar to the head drop of water with potential energy; and the reconstructed 'elevator' is used to generate power.

Primary oil long-distance pipeline electric heating membrane safety heating system and construction method

The invention relates to a crude oil long-distance pipeline electric heating membrane safe heating system for preventing coagulation when crude oil long-distance pipeline transport is stopped, and a construction method thereof is also disclosed. A rare earth electric heating membrane (3) is coated between a solvent-free liquid epoxy paint external anticorrosive layer (2) and solvent-free liquid epoxy paint waterproof layer (4), and an insulation resistance between the rear earth electric heating membrane (3) and a conduit is more than 400 M omega; the electric heating membrane (3) is disposed on the conduit as a plurality of heating units with identical intervals, an electrode (5) is provided at each of the two ends of each heating unit, the heating units are connected one by one in parallel by power supply lines (6), a set of buried transformer and rectifier is provided with each two heating units, output AC voltage is supplied to the heating units, and 220-1000V AC voltage is supplied ...

Outside arc surface film coating method of bent tempered glass and low emissivity coated glass prepared by same

The invention relates to an outside arc surface film coating method of bent tempered glass and a low emissivity coated glass prepared by same, belonging to the field of the preparation of the low emissivity glass. The outside arc surface film coating method of the bent tempered glass is characterized by comprising the following steps: (1) performing bent tempering treatment to the float glass substrate to obtain bent glass; and (2) placing the bent glass in an off-line vacuum plating device to perform horizontal film coating, wherein before the step 2, a polishing glass machine is used to polish the bent outside arc surface and then a cleaning step is performed; the polishing powder used in polishing is cerium oxide with the grain size which is not more than 0.9mu m, and the polishing slurry comprises the following components by weight percent: 30-50% of cerium oxide and the balance water. The method of the invention overcomes the problems of outside arc surface coated glass and obtains ...

Method for preparing ruthenium-containing corrosion resistant titanium alloy

A method for preparing ruthenium-containing corrosion-resistant titanium alloy relates to a method for adding the element ruthenium to the titanium ingot smelting, and is applied to the procedure of preparing titanium and titanium alloy in the fields, such as nuclear power, metallurgy, petrochemical engineering and the like. The method, which adopts the materials of sponge titanium and master alloy to press electrodes and the preparation method of vacuum arc smelting, is characterized in that the alloy composition ruthenium is added in the form of powder when the electrodes are pressed. All you need to do for realizing the new smelting process for preparing the ruthenium-containing titanium alloy without changing the original process for preparing the titanium and the titanium alloy is to add the ruthenium powder in a certain amount to the procedure of pressing the electrodes, and the prepared element ruthenium is evenly distributed without metallurgical defects, such as inclusion and the ...

Method for detecting errors of and automatically resetting encryption chip in encryption card

The invention provides a method for detecting errors of and automatically resetting an encryption chip in an encryption card. The method is characterized by comprising a monitoring control chip and comprises the following steps: high-level application software sends an encryption/decryption command or data to the encryption chip via the monitoring control chip; the monitoring control chip automatically adds a chip monitoring command to the head of the encryption/decryption command; after the monitoring command enters into the encryption chip, the encryption chip returns own inner state information; the monitoring control chip judges the inner state information of the encryption chip, sends a reset command and resets the encryption chip if the inner state information is inconsistent with the expected value and continuously carries out encryption/decryption if the inner state information is consistent with the expected value; and in the encryption/decryption process, the monitoring control ...

Intermediate of flavonoid compound and preparation method and application thereof

The invention discloses an intermediate of a flavonoid compound shown in a formula L and a preparation method thereof. In the mixed solvents of a non-protonic solvent and an alcohol solvent, under the action of an alkaline reagent, the compound shown in the formula M undergoes selective dehydroxylation protecting group reaction, wherein R1 is -CO(CH2)nCH3 or benzoyl; and n ranges from 0 to 8. Theinvention also relates to application of the intermediate of the flavonoid compound shown in the formula L in preparation of the flavonoid compound shown in the formula A. Compared with the conventional method for separating and extracting the flavonoid compound shown in the formula A from the plant, the method for preparing the flavonoid compound shown in the formula A from the intermediate of the flavonoid compound shown in the formula L can realize large-scale industrialized production, and has the advantages of simple steps, no special reagent or harsh requirements on reaction conditions,and ...

Novel pleuromutilin derivate, preparation method and medical use thereof

The invention discloses a pleuromutilin derivate, a preparation method and medical use thereof. The pleuromutilin derivate is a compound, which is obtained by coupling pleuromutilin to alkyl acylamino-thiazole-4-methyl merecaptan with 2-different substitutional amino. Pharmacological experimental results show that: compared with the pleuromutilin, the pleuromutilin derivate disclosed by the invention has better antimicrobial and antibiotic resistant bacteria activities; and therefore, the compound is possibly applicable for curing a plurality of infection and inflammatory diseases on clinic.

Modulation method of continuous casting electromagnetic stirring magnetic field generator

The invention relates to a modulation method of a continuous casting electromagnetic stirring magnetic field generator, which is realized by modulating an induction coil in a water cooling jacket shell. The method comprises the steps of: introducing current, the frame/ frequency/ phase of which can be singly modulated or modulated along with each other, into an induction coil so as to generate a magnetic field, the frame/ frequency/ phase of which can be singly modulated or modulated along with each other, in molten metal within the control range of the metal coil, in order to correspondingly and independently or simultaneously adjust the magnitude, the action point and the direction of electromagnetic force acting on the molten metal, thereby accurately controlling the molten metal to flow in order to control the solidification process of continuous casting metal, and further achieve the purpose of improving casting blank quality.

Method for preparing epoxy fatty acid methyl ester

The invention relates to an improved method for preparing epoxy fatty acid methyl ester, which is characterized in that a solid catalyst or a sodium bisulfate solid catalyst obtained by mixing 30-90 parts of sodium bisulfate, 10-50 parts of ferric sulfate and 0-20 parts of calcium sulfate is adopted in an epoxidation reaction. By using the solid catalyst, when catalytic activity of the solid catalyst corresponds to that of sulfuric acid, the reaction condition is temperate; the production safety is good; the obtained product has high epoxy value which can reach more than 3.5; the epoxidation temperature is reduced to a certain degree, for example, the reaction temperature can be reduced by about 10 DEG C; and because too high temperature is needless, the fatty acid eater is not easy to becarbonized; the obtained product has light and bright color and luster and can be directly used for a light-color product without a decolorization process; the yield is also enhanced; and particularly the ...

Self-healing capacitor component having internal protection

The invention relates to the manufacturing field of a self-healing power capacitor, in particular to a self-healing capacitor element with internal protection function. The self-healing capacitor element comprises a case body and a cylinder body formed by winding at least two layers of metallized films on a hollow tube, a first pole plate lead and a second pole plate lead are led out from the two ends of the cylinder body, and the cylinder body is encapsulated in the case body. The self-healing capacitor element with the internal protection function is characterized in that the second pole plate lead is led out to the other end of the cylinder body by the hollow tube, the middle of the second pole plate lead is serially connected with fuses and the fuses are arranged in the hollow tube.

Microbial inoculum for bioremediating coastline polluted by oil spilling and preparation method thereof

The invention discloses a microbial inoculum for bioremediating a coastline polluted by oil spilling and a preparation method thereof. The microbial inoculum for bioremediating the coastline polluted by oil spilling is made of mixed fermentation liquor and a fixed carrier as raw materials, wherein the mixed fermentation liquor comprises bacillus pumilus CGMCCnO.3384 fermentation liquor, Venice acinetobacter CGMCCnO.3385 fermentation liquor and/or Doxa pseudomonad CGMCCnO.3386 fermentation liquor and/or Ralstonia pickettii CGMCCnO.3387 fermentation liquor. By using the synergic action of different strains on the degradation of various petroleum hydrocarbons, the microbial inoculum improves the degradation speed of petroleum hydrocarbon pollutants and thoroughly degrades various petroleum hydrocarbon pollutants; in addition, a flora formed by a plurality of strains of bacteria has more stable structure and can better adapt to various petroleum-polluted environments. The microbial inoculum ...

Intermediate of flavonoid compound and preparation method and application thereof

The invention discloses an intermediate of a flavonoid compound shown in a formula D and a preparation method thereof. In a non-protonic solvent, under the action of a reagent for condensation, the compound shown in the formula E reacts with 2,3,4-triphenyl formyloxy rhamnose shown in the formula I, wherein R1 is -CO(CH2)nCH3 or benzoyl; n ranges from 0 to 8; Bn is the benzyl; and Bz is the benzoyl. The invention also relates to application of the intermediate of the flavonoid compound shown in the formula D in preparation of the flavonoid compound shown in the formula A. Compared with the conventional method for separating and extracting the flavonoid compound shown in the formula A from the plant, the method for preparing the flavonoid compound shown in the formula A from the intermediate of the flavonoid compound shown in the formula D can realize large-scale industrialized production, and has the advantages of simple steps, no special reagent or harsh requirements on reaction conditions ...

THE CRYSTALLINE FORM OF THE DIHYDROCHLORIDE SALT (1 - (1S) - ((2 - (2S) - (5 - (4' - (2 - ((2S) - 1 - ((2S) -2 ((METHOXYCARBONYL) AMINO-) - 3 A-METILBUTANOIL) 2 P-I-R-R OR L-I-I D-N-L-) -1 OF H-I'M-I-D TO Z OR L-5 I-I) 4 A-BIPHENYLYL) - 1H-IMIDAZOLE-A 2-YL) - 1-PYRROLIDINYL) CARBONYL) - 2 A-METHYLPROPYL) METHYL CARBAMATE

Una forma cristalina de sal diclorhidrato de ((1S)-1-(((2S)-2-(5-(4-(2-((2S)-1-((2S)-2-((metoxicarbonil)amino)-3-metilbutanoil)-2-pirrolidinil)-1H-imidazol-5-il)-4-bifenilil)-1H-imidazol-2-il)-1-pirrolidinil)carbonil)-2-metilpropil)carbamato de metilo. También, a una composición farmacéutica que comprende una forma cristalina, así como a procedimientos de uso de una forma cristalina en el tratamiento de hepatitis C y a procedimientos para obtener dicha forma cristalina. Reivindicación 1: Forma N-2 caracterizada por ser un compuesto de fórmula (1).

Novel security inspection door

The invention belongs to the technical field of detection and in particular discloses a novel security inspection door. In the security inspection door, a radioactive detection system is arranged in a metal detection system, wherein a radioactive detector is arranged in a small coil or arranged between a big coil and the small coil and outside the magnetic lines between the big coil and the small coil or arranged between the big coil and the small coil and coated with a screening layer. The security inspection door smartly solves the problem of the interference of the radioactive detection system with and realizes the integration of the metal detection and radioactive detection of the security inspection door.

REVERSE-JET SWIRL PULVERIZED COAL BURNER WITH MULTI-STAGE RECIRCULATIONS

A reverse-jet swirl pulverized coal burner with multi-stage recirculations includes a pre-combustion housing, a primary coal-air structure, a rich-lean output structure, an inner secondary air structure, and an outer secondary air structure. The pre-combustion housing has a pre-combustion chamber and a housing outlet. The primary coal-air structure is configured to separate a primary coal-air flow into a fuel-rich coal-air flow and a fuel-lean coal-air flow. The rich-lean output structure is configured to output the fuel-lean coal-air flow and block the fuel-rich coal-air flow to make the fuel-rich coal-air flow reversely flow to the pre-combustion chamber. The inner secondary air structure is configured to introduce an inner secondary air into the pre-combustion chamber, thereby forming a first-stage recirculation zone in the pre-combustion chamber and forming a second-stage recirculation zone. The outer secondary air structure is configured to form a third-stage recirculation zone at the housing outlet. 1. A reverse-jet swirl pulverized coal burner with multi-stage recirculations , comprising:a pre-combustion housing, the pre-combustion housing having a pre-combustion chamber and a housing outlet located on one side of the pre-combustion chamber;a primary coal-air structure passing through the pre-combustion housing and extending into the pre-combustion chamber, the primary coal-air structure being configured to separate a primary coal-air flow into a fuel-rich coal-air flow and a fuel-lean coal-air flow, and an outlet end of the primary coal-air structure extending toward the housing outlet;a rich-lean output structure disposed at the outlet end of the primary coal-air structure, the rich-lean output structure being configured to output the fuel-lean coal-air flow and block the fuel-rich coal-air flow to make the fuel-rich coal-air flow reversely flow to the pre-combustion chamber;an inner secondary air structure disposed on the pre-combustion housing and around ...

Extra-cellular polysaccharide of aerobic Ruthia sp. strain metabolin and preparation and application thereof

The invention relates to an extra-cellular polysaccharide of aerobic Ruthia sp. strain metabolin and preparation and application thereof. An aerobic strain ZHT4-13 is separated from adhesive sludge ofwild Ruditapes philippinarums in the Bohai sea offshore of China and is identified as a Ruthia sp. The aerobic strain is treated by seed culture and amplification culture, and a fermentation broth ofthe aerobic strain is precipitated with ethanol and separated centrifugally to obtain the extra-cellular polysaccharide MBF4-13. The extra-cellular polysaccharide MBF4-13 is measured to have high flocculation activity, the FR value to kaolin reaches over 80 percent, and the removal rate to hexavalent chromium ions reaches 69.3 percent; the extra-cellular polysaccharide MBF4-13 has high activity to decolorize high-concentration wastewater, and the decolorization ratios to methylene blue, ink blue, malachite green and crystal violet reach 86.11 percent, 99.49 percent and 97.84 percent; and theextra-cellular ...

Method for obtaining image of human faces by using active light source

A method for obtaining man-face image by active light source is to apply an active light source to radiate the man-face zone by the active light source, shoot the man-face with an electronic image collection device to acquire a related image and transfers said image to related electronic computing process device to identify the man-face image, among which, the image energy generated on the man-face part by the active light source is far more larger than that by environmental light source, which effectively reduces influence of light variance on image of man-face under different radiation environments, so as to get high accurate man-face identification.

银杏叶组合物及制备方法与应用

... 本发明提供了由银杏叶中提取出的不同的组合物，所述的组合物含有新的活性成份，本发明同时提供组合物及该组合物中单个成份的制备方法，本发明提供了该组合物不同的应用。 ...

Intermediate of flavonoid compound and preparation method and application thereof

The invention discloses an intermediate of a flavonoid compound shown in a formula D and a preparation method thereof. In a non-protonic solvent, under the action of a reagent for condensation, the compound shown in the formula E reacts with 2,3,4-triphenyl formyloxy rhamnose shown in the formula I, wherein R1 is -CO(CH2)nCH3 or benzoyl; n ranges from 0 to 8; Bn is the benzyl; and Bz is the benzoyl. The invention also relates to application of the intermediate of the flavonoid compound shown in the formula D in preparation of the flavonoid compound shown in the formula A. Compared with the conventional method for separating and extracting the flavonoid compound shown in the formula A from the plant, the method for preparing the flavonoid compound shown in the formula A from the intermediate of the flavonoid compound shown in the formula D can realize large-scale industrialized production, and has the advantages of simple steps, no special reagent or harsh requirements on reaction conditions ...

Method for preparing biological diesel oil from waste animals and plants grease

The improved continuous esterification process of waste animal and vegetable oil and grease with low carbon alcohol to prepare biodiesel oil features that liquid low carbon alcohol is introduced into the liquid comprising liquid waste animal and vegetable oil and grease in 95-99.9 wt% and acid catalyst in 0.1-5 wt% to produce esterification reaction at normal pressure and the temperature from vaporizing temperature to 95 deg.c while the vapor mixture comprising the resultant, water vapor and low carbon alcohol vapor is discharged from the top of the reactor and separated in a fractionating tower to obtain product, separated water and liquid low carbon alcohol for reuse. The process has high reaction speed, high reaction conversion rate and other advantages, and the product has acid value capable of being controlled below 2 mgKOH/g.

Nutrient cellulose floss and processing method thereof

The nutrient floss contains lean pork-meat, soya bean, potato, carrot, kelp, Xianggu mushroom, Jinzhen mushroom, vegetable and seasoning. Its processing method includes extracting of animal-plant fiber, refining, dewatering of raw material, synthesizing of raw material, puffing of raw-material fiber, taste preparing, puffing of mixed fiber floss, sterilizing and packing. Said product has nutrition and health-care function, and can be used as cooked dishes etc..

Schistosome infectious oncomelania detection kit and detection method thereof

A blood fluke infectious oncomelania detection kit and a detection method thereof belongs to the verminosis transmission medium detecting field. The invention provides a kit and a detection method for detecting blood fluke infectious oncomelania based on a loop-mediated isothermal DNA amplification technology (LAMP). According to the LAMP technology principle, six pairs of specific primers for amplifying a DNA fragment between the 20bp and 231bp of the schistosoma japonicum non-long terminal repeated inverse transcription transposon gene (AF412214) are designed. The LAMP method is constructedfor detecting blood fluke gene in the body of the infectious oncomelania and the objective for distinguishing the blood fluke infectious oncomelania from the non-infectious oncomelania is reached. Comparing to the conventional blood fluke infectious oncomelania detection method the method of the invention has advantages of easy and fast operation, sensitive and specific without especial equipmentand ...

Method for adjusting bent air grid of parallel bent toughening furnace

The invention relates to a method for adjusting a bent air grid of a parallel bent toughening furnace and belongs to the technical field of glass machining. The method comprises adjustment of a lower air grid and adjustment of an upper air grid. In the adjustment of the lower air grid, a template is arranged between the lower air grid and the upper air grid, and one side of the template is a plane and the opposite side of the template is a cambered surface the radius of which is same with the theoretical radius of bent toughened glass, the plane is fixed on a support plate, and the lower air grid is fixed on the cambered surface. In the invention, the template with the cambered surface the radius of which is same with the theoretical radius of the bent toughened glass is made, and the lower air grid is fixed on the curved surface of the template, so that the adjustment of the whole bent air grid becomes simple and can be easily controlled; and the bent toughened glass produced by the invention ...

Double-column gantry numerical control milling machine device

The invention relates to a double-column gantry numerical control milling machine structure which comprises a machine body, a numerical control workbench, a left stand column, a right stand column, a sliding box, a mainshaft box, a mainshaft, a transmission mechanism and a linear motor; wherein the machine body is connected with the ground through anchor bolts; the stand columns are connected with the machine body through bolts; the sliding box slides on a guide rail connected with the stand columns; the mainshaft box slides up and down on the guide rail inside the sliding box; the mainshaft is connected with the mainshaft box through bolts; the numerical control workbench moves along a direction X; the sliding box moves along a direction Y; the mainshaft box moves along a direction Z; and the mainshaft rotates at high speed around an axis through the motor which is integrated with the mainshaft. When the double-column gantry numerical control milling machine structure works, a workpiece ...

Method for realizing webpage fading-in and fading-out in browser

The invention relates to a method for reazlizing webpage fading-in and fading-out in a browser, which comprises the following steps: coding a page element needing the effect, setting a unique identifier, and coding areas to be realized into a DOM layer in a unified way; judging the type of the browser of a terminal user, and responding to a corresponding user mouse roller event; responding to the mouse roller through JavaScript and an event handler; setting initial testing value variables of the roller and event variables; setting a parameter representing a roller rolling distance for an roller rolling event; calculating a fading-in and fading-out degree according to the roller rolling distance; calculating the value of color or transparency to be reached for the control according to the fading-in and fading-out degree to be reached; obtaining the color to be reached for the control according to the transmission value of the roller rolling event and the background color of the upper-layer ...

Intermediate of flavonoid compound and preparation method and application thereof

The invention discloses an intermediate of a flavonoid compound shown in a formula E and a preparation method thereof. In the mixed solvents of a non-protonic solvent and an alcohol solvent, under the action of an alkaline reagent, the compound shown in the formula F undergoes selective dehydroxylation protecting group reaction, wherein R1 is -CO(CH2)nCH3 or benzoyl; n ranges from 0 to 8; and Bn is the benzyl. The invention also relates to application of the intermediate of the flavonoid compound shown in the formula E in preparation of the flavonoid compound shown in the formula A. Compared with the conventional method for separating and extracting the flavonoid compound shown in the formula A from the plant, the method for preparing the flavonoid compound shown in the formula A from theintermediate of the flavonoid compound shown in the formula E can realize large-scale industrialized production, and has the advantages of simple steps, no special reagent or harsh requirements on reaction ...

Intermediate of flavonoid compound and preparation method and application thereof

The invention discloses an intermediate of a flavonoid compound shown in a formula C and a preparation method thereof. In the mixed solvents of a non-protonic solvent and an alcohol solvent, under the action of a catalyst for catalytic hydrogenation, the compound shown in the formula D undergoes catalytic hydrogenation to remove benzyl, wherein R1 is -CO(CH2)nCH3 or benzoyl; n ranges from 0 to 8; Bn is the benzyl; and Bz is the benzoyl. The invention also relates to application of the intermediate of the flavonoid compound shown in the formula C in preparation of the flavonoid compound shown in the formula A. Compared with the conventional method for separating and extracting the flavonoid compound shown in the formula A from the plant, the method for preparing the flavonoid compound shown in the formula A from the intermediate of the flavonoid compound shown in the formula C can realize large-scale industrialized production, and has the advantages of simple steps, no special reagent or ...

Flavonoids compound and synthesis method and application thereof

The invention discloses a flavonoids compound shown as a formula B, wherein R4 is H, glucose group, galactosyl or rhamnose group, and the glucose group, galactosyl or rhamnose group are connected with a mother nucleus through a first-position carbon atom in a group. The invention still discloses a preparation method and application of the compound in preparing a medicine for preventing and controlling cardiovascular and cerebrovascular diseases. The invention also discloses a new midbody compound in preparing the compound. The compound has better dissolubility, has deoxidized glucose in the seventh position so as not to be degraded easily, better activity for controlling cardiovascular and cerebrovascular diseases and lower toxicity. In addition, the compound can be prepared by organic synthesis and greatly reduces cost compared with the condition that most flavonoid glycosides can only be extracted from natural plants, thereby being beneficial to industrialized production.

Method for inserting advertisement in live video advertisement management system

The invention relates to a method for inter-cutting advertisements in a live video advertisement management system, which comprises the following steps: (1) initializing a program list; (2) controlling the program list; and (3) coding and transmitting streams. The method has the advantages of performing 'seamless' switch between advertisement contents and live video contents.

CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROPHENYL)-1,2,3,4- TETRAHYDROISOQUINOLINE AND USE THEREOF

Novel [1,2,4]triazolo[1,5-a]pyridinyl-6-yl-substituted tetrahydroisoquinolines are described in the present invention. These compounds and crystalline forms SA1 and N-2 are used in the treatment of various neurological and physiological disorders. Methods of making these compounds and crystalline forms SA-1 and N-2 are also described in the present invention.

Mono-lysine salts of azole compounds

Card type wideband access management system

The invention relates to a card-type broadband network access management system, comprising: a card-reading terminal for authenticating a user terminal accessing the broadband network, reporting timing information of the card-reading terminal to a user terminal and working state information of the card-reading terminal after the authentication is passed; network management modules for receiving the timing information and working state information reported by the card-reading terminal, receiving clock information that checks clocks of each card-reading terminal; a network management server forreceiving the timing information and working state information transmitted by the network management module in fixed time, uniformly managing and maintaining the received information, and transmitting unified clock information to each network management module. The card-type broadband network access management system provided by the invention is capable of manage and maintain a card-type broadband network ...

Polypropylene soft core-welding method, welder and special-purpose shaping tool thereof

The invention discloses a polypropylene soft core-welding method, a welder and a special-purpose shaping tool thereof. The polypropylene soft core-welding method is characterized in that the ends of broken polypropylene soft cores are first machined, so that the breaking planes are smooth; and the welder depends on two transversely pushing cylinders to respectively clamp the broken polypropylene soft cores, and depends on two longitudinally pushing cylinders to transversely clamp and push the breaking planes of the polypropylene soft cores to get close until the two breaking planes are contacted with a heating plate of the welder, the heating plate is then drawn out, the longitudinal pushing cylinders continue to push the heated breaking planes until the breaking planes are contacted witheach other, and apply pressure on the breaking planes, thereby welding is finished, and the polypropylene soft core is taken out of the welder and cooled to the room temperature. The invention can weld ...

Five-finger independently-driven mechanical artificial hand

The invention discloses a five-finger independently-driven mechanical artificial hand, which comprises five fingers and a wrist and is characterized in that the fingers and the wrist commonly have 19 degrees of freedom, wherein each finger is respectively provided with three joints, i.e. a distal interphalangeal joint, a proximal interphalangeal joint and a metacarprophalangeal joint; three joints of each finger are connected with a drive motor through a first line and a second line so as to draw each finger to move; the wrist is provided with three joints, i.e. a joint rotating around a z shaft, a joint rotating around an x shaft and a joint, which is arranged between the joint rotating around the z shaft and the joint rotating around the x shaft, rotates around a y shaft; and the joints of the wrist are provided with windings of the drive motor for driving the wrist to rotate. Compared with the prior art, five fingers of the mechanical artificial hand have similar joint structures to ...

Anti-schistosoma japonicum Sj14-3-3 protein monoclonal antibody and application thereof in immune diagnosis

The invention discloses an anti-schistosoma japonicum Sj14-3-3 protein monoclonal antibody and application thereof in immune diagnosis, and belongs to the technical field of immune diagnosis of parasitic diseases. The monoclonal antibody against recombinant Sj14-3-3 protein is generated by hybridoma JYQ5C6-1 which has the collection number of CCTCCC201118. The monoclonal antibody against recombinant Sj14-3-3 protein is applied to the detection of an antibody used by schistosoma infected patients or circulating antigen Sj14-3-3 protein in animal blood in schistosoma infected immune diagnosis. The prepared anti-Sj14-3-3 protein molecular specific monoclonal antibody can be used for establishing various immunological diagnosis methods for detecting anti-Sj14-3-3 protein circulating antigens. The time fluorescence resolution method for detecting circulating antigen Sj14-3-3 protein, established by using the anti-Sj14-3-3 protein specific monoclonal antibody, can further improve the accuracy ...

Self-healing capacitor component having internal protection

The invention relates to the manufacturing field of a self-healing power capacitor, in particular to a self-healing capacitor element with internal protection function. The self-healing capacitor element comprises a case body and a cylinder body formed by winding at least two layers of metallized films on a hollow tube, a first pole plate lead and a second pole plate lead are led out from the twoends of the cylinder body, and the cylinder body is encapsulated in the case body. The self-healing capacitor element with the internal protection function is characterized in that the second pole plate lead is led out to the other end of the cylinder body by the hollow tube, the middle of the second pole plate lead is serially connected with fuses and the fuses are arranged in the hollow tube.

Post-edging method of sandwich glass

The invention relates to a post-edging method of sandwich glass, which belongs to the glass processing technology. The post-edging method of sandwich glass comprises the following methods of: (1) selecting the mesh size of diamond wheels, wherein the mesh size of diamond wheel No.1is 120 meshes, and the mesh size of diamond wheel No.2 is 140-180 meshes; (2) adjusting edging quantities, wherein the edging quantity of the diamond wheel No.1is 2-3 mm, and the edging quantity of the diamond wheel No.2 is 0.2-0.4 mm; and (3) adjusting the cooling water quantity, wherein the flow of the sectional area of a general water inlet of cooling water needs to be greater than that of the accumulated total area of the water inlets of all branched pipes, and the total flow of a water pump is greater than 300 L/min. The finished glass processed by the post-edging method has good appearance quality and has no arrisdefect, no edge crack, no blast and so on through selecting the mesh size of the diamond wheels ...

Display assembly of electronic device

Method for switching master mode and slave mode of encryption card and encryption card

The invention provides a method for switching a master mode and a slave mode of an encryption card and the encryption card. The encryption card comprises a power module, a detection module and a mode switching module, wherein the power module detects the power supply situation of a peripheral component interconnect (PCI) or a PCI express (PCIE) interface, and automatically supplies power to the encryption card if the PCI or the PCIE interface cannot be supplied with power; the detection module detects whether a host fails or not, and if the host fails, transmits a mode switching request to the mode switching module; after receiving the mode switching request from the detection module, the mode switching module switches the operating mode of the encryption card from the slave mode to the master mode; and the encryption card independently works in the master mode and continues providing a service for application. Under the condition of normal working of the host, the encryption card exchanges ...

Ginkgo leaves composition and preparation method and uses

Method, device, system and host for three-layer switching

The invention discloses a method, a device, a system and a host for three-layer switching. The method comprises the following steps of: receiving a network message sent by a source virtual machine; according to three-layer switching information acquired in advance, carrying out the three-layer switching treatment of the network message, and generating the network message undergoing the three-layer switching treatment, a virtual link of a destination virtual machine and a three-layer destination address of the destination virtual machine; and according to the three-layer destination address of the destination virtual machine, sending the network message undergoing the three-layer switching treatment to the destination virtual machine by the virtual link of the destination virtual machine. In the technical proposal, the host completes the three-layer switching treatment of the network message according to the three-layer switching information acquired in advance, and sends the network message ...

Card type broadband network access system and method

The invention relates to a card type broadband network access system and a method thereof. The system comprises a card reading terminal for authenticating subscriber terminals accessing the broadband network and forwarding DHCP requests of the subscriber terminals and IP addresses distributed to the subscriber terminals; a two-layer switch for forwarding the DHCP requests of the subscriber terminals and the IP addresses distributed to the subscriber terminals, and for uploading / downloading data information desired by the subscribers; a three-layer switch for distributing IP addresses to thesubscriber terminals. The method comprises steps of the carding reading terminal authenticating subscriber terminals accessing the broadband network, receiving the DHCP requests of the subscriber terminals after the authentication is passed; the two-layer switch receiving the DHCP requests forwarded by the two-layer switch and sending them to the three-layer switch; the three-layer switch distributing ...

Method for preparing biological diesel oil from waste animals and plants grease

The improved continuous esterification process of waste animal and vegetable oil and grease with low carbon alcohol to prepare biodiesel oil features that liquid low carbon alcohol is introduced into the liquid comprising liquid waste animal and vegetable oil and grease in 95-99.9 wt% and acid catalyst in 0.1-5 wt% to produce esterification reaction at normal pressure and the temperature from vaporizing temperature to 95 deg.c while the vapor mixture comprising the resultant, water vapor and low carbon alcohol vapor is discharged from the top of the reactor and separated in a fractionating tower to obtain product, separated water and liquid low carbon alcohol for reuse. The process has high reaction speed, high reaction conversion rate and other advantages, and the product has acid value capable of being controlled below 2 mgKOH/g.

Intermediate of flavonoid compound and preparation method and application thereof

The invention discloses an intermediate of a flavonoid compound shown in a formula L and a preparation method thereof. In the mixed solvents of a non-protonic solvent and an alcohol solvent, under the action of an alkaline reagent, the compound shown in the formula M undergoes selective dehydroxylation protecting group reaction, wherein R1 is -CO(CH2)nCH3 or benzoyl; and n ranges from 0 to 8. The invention also relates to application of the intermediate of the flavonoid compound shown in the formula L in preparation of the flavonoid compound shown in the formula A. Compared with the conventional method for separating and extracting the flavonoid compound shown in the formula A from the plant, the method for preparing the flavonoid compound shown in the formula A from the intermediate of the flavonoid compound shown in the formula L can realize large-scale industrialized production, and has the advantages of simple steps, no special reagent or harsh requirements on reaction conditions, and ...

Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1h-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1h-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine

The instant disclosure provides crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine, salts and solvates thereof. The present disclosure also generally relates to pharmaceutical compositions comprising the crystalline form(s), as well of methods of using the crystalline form(s) in the treatment of HIV and/or AIDS, and methods for obtaining such crystalline form(s).

Outside arc surface film coating method of bent tempered glass and low emissivity coated glass prepared by same

The present invention relates to an outside arc surface film coating method of bent tempered glass and a low emissivity coated glass prepared by same, belonging to the field of the preparation of the low emissivity glass. The outside arc surface film coating method of the bent tempered glass is characterized by comprising the following steps: (1) performing bent tempering treatment to the float glass substrate to obtain bent glass; and (2) placing the bent glass in an off-line vacuum plating device to perform horizontal film coating, wherein before the step 2, a polishing glass machine is used to polish the bent outside arc surface and then a cleaning step is performed; the polishing powder used in polishing is cerium oxide with the grain size which is not more than 0.9mu, and the polishing slurry comprises the following components by weight percent: 30-50% of cerium oxide and the balance water. The method of the invention overcomes the problems of outside arc surface coated glass and obtains ...

银杏叶组合物及制备方法与应用

The invention refers to a kind of compound material which is extracted from gingko leaf, especially refers to the method for certifying and analyzing the flavone, terpene ester, gingko acid, total flavone, flavone alcohol glucoside in the compound.

Method for preparing epoxy fatty acid methyl ester

The invention relates to an improved method for preparing epoxy fatty acid methyl ester, which is characterized in that a solid catalyst or a sodium bisulfate solid catalyst obtained by mixing 30-90 parts of sodium bisulfate, 10-50 parts of ferric sulfate and 0-20 parts of calcium sulfate is adopted in an epoxidation reaction. By using the solid catalyst, when catalytic activity of the solid catalyst corresponds to that of sulfuric acid, the reaction condition is temperate; the production safety is good; the obtained product has high epoxy value which can reach more than 3.5; the epoxidation temperature is reduced to a certain degree, for example, the reaction temperature can be reduced by about 10 DEG C; and because too high temperature is needless, the fatty acid eater is not easy to be carbonized; the obtained product has light and bright color and luster and can be directly used for a light-color product without a decolorization process; the yield is also enhanced; and particularly ...

Square rule

The utility model relates to a square gauge which is suitable for drawing square figures. The utility model is composed of two ruler strips 1, a line drawing pen 2, an orbit 3, a line pull pen 4, a button 5, etc., wherein the two ruler strips are connected by a pin shaft and can be doubled over into a right angle, and the line drawing pen can be pulled to a predetermined position in advance; when the button is pressed, the line drawing pen is pulled back, and thus, two square sides can be drawn; after the foregoing operation is repeated for one time, the square figure can be drawn. The square gauge can be used as a teaching aid, or stationery, or other tools.

Method and system for using a virtualization system to identify deadlock conditions in multi-threaded programs by controlling scheduling in replay

A method and system for determining potential deadlock conditions in a target multi-threaded software application. The target application is first run in a virtual machine and the events within the application are recorded. The recorded events are replayed and analyzed to identify potential lock acquisition conflicts occurring between threads of the application. The potential lock acquisition conflicts are identified by analyzing the order in which resource locks are obtained and pairs of resources that have respective locks obtained in different orders are analyzed. These analyzed pairs are used to define a different order of events in the target application that, when the target application is re-run with the second order of events, may trigger a deadlock condition. The target application is then re-run with the different order of events in an attempt to trigger and then identify potential deadlock situations.

PREPARATION METHOD OF HIGH-PURITY TOTAL GINKGO FLAVONOL GLYCOSIDE AND APPLICATION OF SAME

The present disclosure relates to the field of pharmacology, and in particular, to a preparation method of high-purity total ginkgo flavonol glycoside. The preparation method of high-purity total ginkgo flavonol glycoside includes: (1) mixing extract powder and a first alkaline solution, subjecting to dissolution and centrifugation to obtain a supernatant; (2) subjecting the supernatant to separation with an acid-polar coupled macroporous resin column and to purification with a polyamide column, to obtain high-purity total ginkgo flavonol glycoside. The purity of the total ginkgo flavonol glycoside prepared by the preparation method of high-purity total ginkgo flavonol glycoside according to the present disclosure is ≥90%, and has good clinical application prospects; the preparation process does not require organic reagents such as petroleum ether and ethyl acetate, which is environmentally friendly; the transfer rate of the total flavonol glycoside is high. 1. A method for preparing a total ginkgo flavonol glycoside , comprising the following operations:{'i': 'Ginkgo biloba', '(1) mixing extract powder with a first alkaline solution, subjecting to dissolution and centrifugation to obtain a supernatant;'}(2) subjecting the supernatant to separation and purification by an acid-polar coupled macroporous resin column and a polyamide column, to obtain a high-purity total ginkgo flavonol glycoside.2. The preparation method according to claim 1 , wherein the dissolution in operation (1) is an ultrasonic treatment claim 1 , and an ultrasonic time is 30˜60 minutes.3. The preparation method according to claim 1 , wherein the first alkaline solution is a NaCOaqueous solution with a mass fraction of 0.1˜0.4%.4. The preparation method according to claim 1 , wherein operation (2) comprises: loading the supernatant onto the acid-polar coupled macroporous resin column claim 1 , and eluting with a second alkaline solution to obtain an eluent; drying the eluent to obtain a solid ...

COMPOSITION FOR INHIBITING RESPIRATORY VIRUSES AND RESPIRATORY VIRUS PREVENTION AND TREATMENT METHOD

A composition inhibits respiratory viruses and a method prevents and treats a respiratory. Respiratory viral infections are extremely common clinically, but the current therapeutic drugs for viral infections still cannot meet the treatment needs. An inhalant inhibits respiratory viruses and adopts a method of inhaling high-temperature acetic acid steam for prevention and treatment. Acetic acid in the high-temperature steam can release hydrogen ions to inactivate viruses in the respiratory tract, so as to prevent the onset of the disease and provide a therapeutic effect. In addition, the composition can be used to inhibit fungi and bacteria in vitro and prevent skin diseases and respiratory diseases caused by bacteria and fungi. The prevention and treatment method is easy to implement and has low costs and important clinical application value. 1. A composition for inhibiting respiratory viruses , wherein acetic acid is used as an active ingredient in the composition; the active ingredient for inhibiting respiratory viruses in the composition is high-temperature steam of an acetic acid solution; and the steam acting on viruses is at 50° C. or above2. The composition for inhibiting respiratory viruses according to claim 1 , wherein the composition further comprises one or any mixture of ethanol and oxygen; further claim 1 , the composition comprises acetic acid;or, the composition comprises acetic acid and oxygen;or, the composition comprises acetic acid and ethanol;or, the composition comprises acetic acid, oxygen and ethanol;or, the composition also comprises anti-inflammatory drugs, antiviral drugs and immunomodulatory drugs.3. An inhalant for inhibiting respiratory viruses claim 1 , wherein the inhalant comprises the composition according to .4. The inhalant for inhibiting respiratory viruses according to claim 3 , wherein the inhalant comprises an acetic acid solution claim 3 , and the concentration of the acetic acid solution is 0.01%-10%;or, the inhalant is a ...

DATA MIGRATION BETWEEN DIFFERENT TYPES OF STORAGE SYSTEMS

Data migration from a source data storage system to a target data storage system, where the source and target data storage systems are of two different types, using a virtual file system to store the data at the target data storage system, with the target data storage system being configured to store data in the manner of the source data storage system. In some embodiments, more convenient and efficient data migration can be provided without changing the architecture of an existing data storage system as far as possible. 1. A method for data migration , the method comprising:receiving a migration request for data migration from a source storage system to a target storage system, with the source storage system and the target storage system being of different types of storage systems;building a virtual file system for reading data blocks in the source storage system; andmigrating a plurality of data blocks in the source storage system to the target storage system via the virtual file system.2. The method according to claim 1 , wherein the building of the virtual file system for reading data blocks in the source storage system comprises:obtaining a source file system description of the source storage system and a target file system description supported by the target storage system; andbuilding the virtual file system on the basis of the source file system description and the target file system description.3. The method according to claim 1 , wherein the virtual file system is implemented in the target storage system.4. The method of further comprising:in response to detecting an access request of a client to the source storage system, guiding the access request to the target storage system; andproviding, by the target storage system, a data block requested by the access request.5. The method of wherein the migrating of data blocks in the source storage system to the target storage system via the virtual file system comprises:with respect to data blocks in the source ...

INTEGRIN INHIBITOR AND USES THEREOF

Provided herein are integrin inhibitors, compositions thereof, and methods of their uses. Crystalline forms of salts of the inhibitors are also described, along with methods of preparing the crystalline forms. X-ray powder diffraction data, thermogravimetric analysis, and differential scanning calorimetry data are provided for the crystalline forms. The integrin inhibitors are useful for treatment of, inter alia, fibrotic diseases. 1. A crystalline form of a salt of (S)-4-((2-methoxyethyl)(4-(5 ,6 ,7 ,8-tetrahydro-1 ,8-naphthyridin-2-yl)butyl)amino)-2-(quinazolin-4-ylamino)butanoic acid or a solvate thereof.2. The crystalline form of claim 1 , wherein the crystalline form is a crystalline form of a phosphate salt of the (S)-4-((2-methoxyethyl)(4-(5 claim 1 ,6 claim 1 ,7 claim 1 ,8-tetrahydro-1 claim 1 ,8-naphthyridin-2-yl)butyl)amino)-2-(quinazolin-4-ylamino)butanoic acid.3. The crystalline form of claim 2 , wherein the crystalline form is characterized as having an X-ray powder diffraction (XRPD) pattern comprising:a. peaks at angles 2-theta of about 4.31, about 6.76, about 18.89, about 21.29, and about 23.16 degrees,b. peaks at angles 2-theta of about 4.31, about 6.76, about 11.25, about 12.75, about 18.89, about 20.38, about 21.29, about 23.16, about 23.97, and about 24.68 degrees, orc. peaks at angles 2-theta of about 4.31, about 6.76, about 8.55, about 10.04, about 11.25, about 12.75, about 13.76, about 17.20, about 18.02, about 18.89, about 20.38, about 21.29, about 23.16, about 23.97, about 24.68, about 25.50, about 26.18, about 29.88, and about 33.49 degrees.4. The crystalline form of claim 2 , wherein the crystalline form is characterized as having an XRPD pattern comprising peaks at angles 2-theta of about 4.31 and about 6.76 degrees.5. The crystalline form of claim 2 , wherein the crystalline form is characterized as having an XRPD pattern comprising a peak at an angle 2-theta of about 4.31 degrees.6. The crystalline form of claim 2 , wherein the ...

RADIOTHERAPY SYSTEM

A radiotherapy system includes radiotherapy equipment and at least one source storage tank. The radiotherapy equipment includes a treatment head and a radioactive source component, the treatment head includes a first opening and an accommodation space, and the radioactive source component is located in the accommodation space of the treatment head; the source storage tank includes a tank body and a tank cover, the tank body includes a second opening and an accommodation space capable of accommodating the radioactive source component, and the tank cover is configured to close the second opening; the second opening of the source storage tank is connected to the first opening of the radiotherapy equipment, and the radioactive source component is movable between the treatment head and the source storage tank. 1. A radiotherapy system , comprising radiotherapy equipment and at least one source storage tank , wherein the radiotherapy equipment includes a treatment head and a radioactive source component , the treatment head includes a first opening and an accommodation space , and the radioactive source component is located in the accommodation space of the treatment head;the source storage tank includes a tank body and a tank cover, the tank body includes a second opening and an accommodation space capable of accommodating the radioactive source component, and the tank cover is configured to close the second opening; andthe second opening of the source storage tank is configured to connect to the first opening of the radiotherapy equipment, and the radioactive source component is able to move between the treatment head and the source storage tank.2. The radiotherapy system according to claim 1 , wherein the source storage tank is fixedly disposed on the radiotherapy equipment.3. The radiotherapy system according to claim 1 , wherein the second opening includes a first sub-opening and a second sub-opening disposed oppositely the first sub-opening is configured to connect ...

REVERSAL-POINT-BASED DETECTION AND RANKING

In an example embodiment, a model is trained to specifically identify reversal points in data and then to rank these reversal points in order of importance. A reversal point shall be defined as a point in which a particular metric, specifically a first order derivative, crosses over from positive to negative or vice-versa. Users are more likely to be interested in abnormal and significant changes in data, and thus the machine-learned model is trained to evaluate a reversal point based on two dimensions: abnormality and significance. 1. A system for training and using a machine learned model , comprising:a computer-readable medium having instructions stored thereon, which, when executed by a processor, cause the system to perform operations comprising:obtaining time series data, the time series data including a value for a first metric at each of a plurality of time points separated by time intervals;identifying, in the time series data, a plurality of reversal points, a reversal point being a time point at which the value for the first metric changed from positive to negative or vice-versa;obtaining training data from one or more databases; [ determining a difference between a length of a trend, prior to the input reversal point, in a segment of the time series containing the input reversal point and a total number of reversal points in a plurality of reversal points in the segment, wherein a trend is a sequence of time points at which the value for the first metric maintained a same sign;', 'dividing the difference by a value computed based on a total number of time points in the segment;, 'calculating an abnormality score by, 'determining a maximum absolute value of differences between a magnitude change at the input reversal point and those magnitude changes in the trend in the segment prior to the input reversal point;', 'calculating a significance score by, 'applying a first weight to the abnormality score and a value related to the first weight to the ...

Plasma Doping Using A Solid Dopant Source

A method of processing a workpiece is disclosed, where the interior surfaces of the plasma chamber are first coated using a conditioning gas that contains the desired dopant species. A working gas, which does not contain the desired dopant species, is then introduced and energized to form a plasma. This plasma is used to sputter the desired dopant species from the interior surfaces. This dopant species is deposited on the workpiece. A subsequent implant process may then be performed to implant the dopant into the workpiece. The implant process may include a thermal treatment, a knock in mechanism, or both. 1. A method of depositing a dopant species on a workpiece , comprising: introducing a conditioning gas into a plasma chamber of an ion source, the conditioning gas comprising a dopant species; and', 'ionizing the conditioning gas in said plasma chamber so as to form a coating, which comprises the dopant species in solid form, on interior surfaces of the plasma chamber; and, 'performing a conditioning process, the conditioning process comprising introducing a working gas into the plasma chamber after the coating is formed, wherein the working gas does not comprise the dopant species; and', 'ionizing the working gas in said plasma chamber to create ions and sputter the coating, such that the dopant species is deposited on the workpiece., 'performing a deposition process after the conditioning process, the deposition process comprising2. The method of claim 1 , wherein the workpiece is not disposed in the plasma chamber during the conditioning process.3. The method of claim 1 , wherein the working gas comprises an inert gas.4. A method of implanting a dopant species in a workpiece claim 1 , comprising: introducing a conditioning gas into a plasma chamber of an ion source, the conditioning gas comprising a dopant species; and', 'ionizing the conditioning gas in said plasma chamber so as to form a coating, which comprises the dopant species in solid form, on interior ...

Radioactive source removing and introducing tooling, smart cart and source removing and introducing system

A radioactive source removing and introducing tooling includes a first support frame, a shield door disposed on the first support frame, a shield cover located on the shield door, and a first pull rod device. The shield door includes a movable first shield block. The shield cover is able to be separated from the shield door, and the shield cover includes one opening and one accommodation space. The first pull rod device includes a pull rod and a first connection portion disposed on the pull rod, and the pull rod is able to extend into the shield cover and drive the first connection portion to move inside the accommodation space of the shield cover.

PIPE MATERIAL

The present invention discloses a pipe material including the pipe body. Spacers are set inside the pipe body. The outer wall of the spacer is in close fit with the inner wall of the pipe body. In the present invention, the spacer set inside the pipe material can well support the pipe wall and better enhance the mechanical strength and anti-bending performance of the pipe. Due to the close fit between the outer wall of the spacer and the inner wall of the pipe body, the bonding between the spacer with certain thickness and the pipe body enhances its force in any direction and improves the stress performance of the pipe body. The interaction of multiple spacers ensures the local stability of the pipe body between spacers. The interaction between the spacer and the pipe wall ultimately improves various performances of the pipe, especially its anti-bending performance. 1. A pipe material including the pipe body , wherein spacers are set inside the pipe body that are in close fit with the inner wall of the pipe.2. A pipe material according to claim 1 , wherein the cross section of the spacer is impeller-shaped.3. A pipe material according to claim 1 , wherein an adhesive layer is set between the outer wall of the spacer and the inner wall of the pipe body.4. A pipe material according to claim 1 , wherein the end face of the spacer is concave.5. A pipe material according to claim 1 , wherein a control handle is set on the end face of the spacer.6. A pipe material according to claim 1 , wherein multiple spacers are set at a connecting rod to form a spacer string.7. A pipe material according to claim 1 , wherein a reinforcing ring which is in close fit with the outer wall of the pipe body is set outside the pipe body.8. A pipe material according to claim 7 , wherein the reinforcing ring corresponds with the spacer set inside the pipe body.9. A pipe material according to claim 8 , wherein the reinforcing ring is in magnetic connection with the spacer set inside the pipe ...

METHOD FOR PREPARING HIGH-PURITY TOTAL GINKGOLIDE AND USE THEREOF

The present disclosure relates to the field of pharmacy, specifically to a method for preparing a high-purity ginkgolide and a use thereof. The method for preparing total ginkgolide includes the following steps: (1) mixing a extract powder with an alkali solution, obtaining a precipitate by dissolving and centrifuging; (2) obtaining a total ginkgolide concentrate through purifying the precipitate by silica gel column and recrystallizing. The preparation method of total ginkgolide provided in the present disclosure can improve the purity of total ginkgolide, and the purity of the prepared total ginkgolide is ≥80%, which has good clinical application prospect; and the preparation process does not require complicated multi-step recrystallization step, and the total ginkgolide yield is high. 1. A method for preparing total ginkgolide , comprising the following steps:{'i': 'Ginkgo biloba', '(1) mixing a extract powder with an alkali solution, obtaining a precipitate by dissolving and centrifuging;'}(2) obtaining a total ginkgolide concentrate through purifying the precipitate by a silica gel column and recrystallizing.2. The preparation method as in claim 1 , whereinthe filler in the silica gel column is silica gel.3. The preparation method as in claim 2 , whereinthe filler in the silica gel column is pretreated with chloroform:methanol=(10:1) to (100:1).4. The preparation method as in claim 2 , whereinthe filler in the silica gel column has a mesh number of 100 to 300.5. The preparation method as in claim 1 , whereinthe silica gel column has a diameter to height ratio of 1:4 to 1:10.6. The preparation method as in claim 1 , whereinthe absorption ratio of the silica gel column is 1:30 to 1:50.7. The preparation method as in claim 1 , whereinstep (2) comprises: dissolving the precipitate in dichloromethane:methanol=(1:1) to (3:1), and loading the silica gel column.8. The preparation method as in claim 7 , whereinafter loading the silica gel column, a first elution is ...

APPARATUS FOR ASSESSING MEDICAL DEVICE QUALITY

The present invention relates to an apparatus for assessing medical device quality. It is described to provide () at least one report associated with at least one medical image acquired by a medical device, wherein a report is associated with a corresponding medical image. The at least one report is analyzed and at least one image quality parameter is generated (), wherein an image quality parameter is associated with a 5 corresponding report. The at least one image quality parameter is assessed and generating alert information relating to the medical device is generated (). 1. An apparatus for assessing medical device quality , comprising:an input unit; anda processing unit;wherein, the input unit is configured to provide the processing unit with at least one report associated with at least one medical image acquired by a medical device, wherein a report is associated with a corresponding medical image;wherein, the processing unit is configured to implement a classifier module to analyze the at least one report and generate at least one image quality parameter, wherein an image quality parameter is associated with a corresponding report, wherein the classifier module is configured to apply a natural language algorithm to the at least one report to generate the at least one image quality parameter, wherein the natural language algorithm comprises a learning algorithm, wherein the learning algorithm is configured to generate a value for an image quality parameter on the basis of at least one training data; andwherein, the processing unit is configured to implement an assessment module to assess the at least one image quality parameter and generate alert information relating to the medical device.2. The apparatus according to claim 1 , wherein a report of the at least one report comprises text and wherein the classifier module is configured to analyze at least one portion of the text to generate an image quality parameter.3. The apparatus according to claim 2 , ...

DATA QUALITY CHECKING BASED ON DERIVED RELATIONS BETWEEN TABLE COLUMNS

In an electronic data processing method, a first column and a second column of at least one table are identified which have a one-to-one or one-to-many relationship with fewer than a threshold number of violations of the one-to-one or one-to-many relationship. On a display, possible data errors in the at least one table corresponding to the violations of the one-to-one or one-to-many relationship are indicated. The identifying of the violations may include generating a weighted bipartite graph representing the first and second columns, and detecting the violations using the bipartite graph. The method may further include displaying, on the display, a user interface whereby a user accepts or rejects each indicated violation of the one-to-one or one-to-many relationship. 1. An electronic data processing system comprising:an electronic processor; and performing pairwise comparisons of columns of at least one table to associate a first column and a second column with a one-to-N relationship by detecting violations of the one-to-N relationship for data of the first and second columns and determining that a count of the violations of the one-to-N relationship for the first and second columns is less than a threshold; and', 'indicating, on a display, possible data errors corresponding to the violations of the one-to-N relationship for data of the first and second columns;', 'wherein the performing and the indicating are performed for the one-to-N relationship being a one-to-one relationship and/or for the one-to-N relationship being a one-to-many relationship., 'a non-transitory storage medium storing instructions readable and executable by the electronic processor to perform an electronic data processing method including2. The electronic data processing system of wherein the comparison of the first and second columns is performed by operations including:generating a weighted bipartite graph representing the first and second columns; anddetecting the violations of the one- ...

MAINTENANCE HISTORY VISUALIZER TO FACILITATE SOLVING INTERMITTENT PROBLEMS

A non-transitory computer readable medium () stores instructions readable and executable by at least one electronic processor () operatively connected with a display () and at least one user input device () to perform a device service support method (). The method includes: identifying attribute values () for attributes () of a plurality of previous service cases () from a service log (); identifying a set of relevant service cases () from the plurality of previous service cases by comparing the identified attribute values for the previous service cases with attribute values for a current service case () using a comparison metric () and a relevance threshold (); plotting, on the display, a timeline () of relevant service cases () of the set of relevant service cases as a function of calendar dates of the relevant service cases; providing a relevance graphical user interface (GUI) dialog () for user adjustment of the relevance threshold via the at least one user input device; and responsive to user adjustment of the relevance threshold via the relevance GUI dialog, repeating the identifying and plotting to dynamically update the plotted timeline on the bases of the user adjustment of the relevance threshold. 1. A non-transitory computer readable medium storing instructions readable and executable by at least one electronic processor operatively connected with a display and at least one user input device to perform a device service support method , the method comprising:identifying attribute values for attributes of a plurality of previous service cases from a service log;identifying a set of relevant service cases from the plurality of previous service cases by comparing the identified attribute values for the previous service cases with attribute values for a current service case using a comparison metric and a relevance threshold;plotting, on the display, a timeline of relevant service cases of the set of relevant service cases as a function of calendar dates of ...

MN-CU-Based Damping Alloy Powder For Use In Selective Laser Melting Process And Preparation Method Thereof

The present invention belongs to the technical field of metal materials for additive manufacturing, and relates to a Mn—Cu-based damping alloy powder for use in a selective laser melting (SLM) process and a preparation method thereof. The powder has chemical components in percent by weight as follows: C: ≤0.15%, Ni: 4.9-5.2%, Si: ≤0.15%, Fe: 1.8-5.0%, Cu: 20-23%, P: ≤0.03%, S: ≤0.06%, and the balance being Mn and inevitable impurities. The preparation method includes: preparation of master alloy, powdering by vacuum induction melting gas atomization (VIGA), mechanical vibrating and air classification screening under protection of an inert gas and collecting. Compared with the prior art, the powder of the present invention has a high sphericity, a high apparent density, a small angle of repose, a desired fluidity and a relatively high yield of fine powders having a size of 15-53 μm. 1. A Mn—Cu-based damping alloy powder for use in a selective laser melting (SLM) process , comprising chemical components in percent by weight as follows: C: ≤0.15% , Ni: 4.9-5.2% , Si: ≤0.15% , Fe: 1.8-5.0% , Cu: 20-23% , P: ≤0.03% , S: ≤0.06% , and the balance being Mn and inevitable impurities.2. A 3D printed manufactured part comprising:{'sup': '−1', 'an alloy comprising chemical components in percent by weight as follows: C: ≤0.15%, Ni: 4.9-5.2%, Si: ≤0.15%, Fe: 1.8-5.0%, Cu: 20-23%, P: ≤0.03%, S: ≤0.06%, and the balance being Mn and inevitable impurities, wherein based on the above components in percent by weight, the 3D printed manufactured part obtained after selective laser melting (SLM) additive manufacturing and heat treatment has a tensile strength >560 MPa at room temperature, a yield strength >300 MPa, an elongation rate of more than 20% and a damping performance Qof above 0.028 at room temperature.'}3. A method of preparing the Mn—Cu-based damping alloy powder for use in an SLM process according to claim 1 , comprising the steps of:preparing a master alloy with vacuum ...

PARTS CO-REPLACEMENT RECOMMENDATION SYSTEM FOR FIELD SERVICING OF MEDICAL IMAGING SYSTEMS

At a service device (), a user interface () is provided via which a user submits an order request () to order a requested part (X) via the at least one user input device (). Co-replacement information () for the requested part (X) is identified using a co-replacements database (), and is displayed on the display. For example, a second part (Y) commonly co-replaced with requested part (X) may be identified and recommended for replacement with part (X); or, if two parts (X) and (Y) are ordered then the co-replacement information may be to recommend ordering only one of these parts. At a server hosting the database (), the order request is received from a service device and the co-replacement information () for the requested part is generated using the co-replacements database (), and the co-replacement information is sent to the service device. 1. A service device comprising:a display;at least one user input device;an electronic processor operatively connected with the display and the at least one user input device; and providing a user interface via which a user submits an order request to order a requested part via the at least one user input device;', 'receiving co-replacement information for the requested part from a server that accesses a co-replacements database;', 'displaying, on the display, the co-replacement information., 'a non-transitory storage medium storing instructions readable and executable by the electronic processor to perform a parts ordering method including2. The service device of wherein:the receiving of co-replacement information for the requested part includes receiving an identification of a second part associated with the requested part, andthe displaying includes recommending co-ordering the second part together with the requested part.3. The service device of wherein the parts ordering method further includes:via the user interface, updating the order request to include the requested part and the second part; andplacing the updated order ...

Enrollment Data Visualization Using Enhanced Graphical User Interface Elements

Various examples are described for enrollment data visualization using enhanced graphical user interface elements. In one example, a management service can receive device data from devices enrolled with the management service, where the management service is configured to remotely oversee operation of the devices. The management service can determine operational metrics using the device data describing operation of the client devices and generate a metric visualization region for display in a user interface. In some examples, the metric visualization region can include a graph plotting the operational metrics over a predefined period of time and a circle having a predefined width circumscribing the graph, where at least a portion of the circle is filled based on the operational metrics.

DEFINING AUTOMATIONS FOR ENROLLED USER DEVICES

Various examples are described for defining automations for client devices enrolled with a management service. A computing environment can cause one or more user interfaces to be shown in a display of an administrator device that include at least one field for receiving a conditional statement to generate an automation associated with client devices enrolled with the management service. The computing environment can validate the conditional statement based on validation criteria and, in an instance in which the conditional statement has been validated, generate the automation based on the conditional statement, the automation causing the computing environment to perform a predetermined action automatically when the conditional statement is satisfied. 1. A system , comprising:at least one computing device comprising at least one hardware processor; and enroll a plurality of client devices with a management service;', 'cause a user interface to be shown in a display of an administrator device, wherein the user interface comprises at least one field for receiving a conditional statement to generate an automation associated with the client devices enrolled with the management service;', 'validate the conditional statement based at least in part on validation criteria; and', 'in an instance in which the conditional statement has been validated, generate the automation based at least in part on the conditional statement that causes the at least one computing device to perform an action automatically when the conditional statement is satisfied., 'program instructions stored in memory and executable in the at least one computing device that, when executed, direct the at least one computing device to2. The system of claim 1 , wherein the at least one computing device is further directed to claim 1 , upon receipt of a device profile corresponding to one of the client device claim 1 , compare the device profile to the automation to determine whether the device profile ...

PROCESS FOR THE PREPARATION OF N,N-DICYCLOPROPYL-4-(1,5-DIMETHYL-1H-PYRAZOL-3-YLAMINO)-6-ETHYL-1-METHYL-1,6-DIHYDROIMIDAZO[4,5-d]PYRROLO[2,3-b]PYRIDINE-7-CARBOXAMIDE

The invention relates to an improved process for synthesizing N,N-dicyclopropyl-4-(1,5-dimethyl-1H-pyrazol-3-ylamino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide of the formula: (I) Compound (I) is currently in clinical trials for the treatment of myeloproliferative disorders, such as polycythaemia vera, thrombocythaemia and primary myelofibrosis. 3. (canceled)4. (canceled)5. (canceled)6. (canceled)7. (canceled)8. (canceled)9. (canceled)10. (canceled)11. (canceled)12. (canceled)14. The method of wherein the suitable palladium source is a PdClsource claim 13 , or Pd(OAc).15. The method of where the suitable potassium source is KOPiv.16. The method of where the suitable phosphine ligand is Xantphos.17. The method of where the optional organic base is Hunig's base.18. (canceled)19. (canceled)20. (canceled)22. (canceled)24. (canceled)25. (canceled) This application claims priority from U.S. Provisional Application No. 61/871,510 filed Aug. 29, 2013, the disclosure of which is incorporated herein by reference in its entirety.The invention generally relates to several improved processes for the preparation of N,N-dicyclopropyl-4-(1,5-dimethyl-1H-pyrazol-3-ylamino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide, a JAK2 inhibitor currently in clinical trials for the treatment of myeloproliferative disorders, which include polycythaemia vera, thrombocythaemia and primary myelofibrosis.There are disclosed significantly improved processes for the preparation of N,N-dicyclopropyl-4-(1,5-dimethyl-1H-pyrazol-3-ylamino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide, of formula I:Compound I, compositions comprising Compound I, and methods of using Compound I are disclosed in U.S. Pat. No. 8,202,881 B2, which is assigned to the present assignee and is incorporated herein by reference in its entirety.In a first aspect, the invention provides a process for preparing Compound I of the ...

PASSENGER COMMUNICATION OUTPUT CONTROL CIRCUIT FOR UNMANNED METRO TRAIN

The present disclosure relates to a passenger communication output control circuit for an unmanned metro train. The unmanned metro train is installed with passenger emergency communication units each having a communication button and a communication relay. The communication relay has a normally-closed contact pair and is linked with the communication button in a one-to-one correspondence. When the communication button is pushed down, the communication relay is energized to disconnect the normally-closed contact pair. The normally-closed contact pairs of all the coaches are connected in series to form an emergency communication circuit. Two terminals of the emergency communication circuit are respectively connected to a train power supply and an input/output module of a TCMS in the coach. When the passenger information system works normally, both a communication network and hardwire can transmit the communication signal. When the two communication signals are inconsistent, the communication signal transmitted by hardwire shall prevail. 1. A passenger communication output control circuit for an unmanned metro train , the unmanned metro train being installed with passenger emergency communication units , each of the passenger emergency communication units having a communication button ,wherein the passenger emergency communication units further comprise communication relays, the communication relays each have a normally-closed contact pair linked to the communication button in a one-to-one correspondence, when the communication button is pushed down, a corresponding communication relay is energized to disconnect the normally-closed contact pair, the normally-closed contact pairs of the communication relays of all coaches of the metro train are connected in series to form an emergency communication circuit, and two terminals of the emergency communication circuit are respectively connected to a train power supply and an input/output module of a train control management ...

CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF

Novel [1,2,4]triazolo[1,5-a]pyridinyl-6-yl-substituted tetrahydroisoquinolines are described in the present invention. These compounds and crystalline forms SA1 and N-2 are used in the treatment of various neurological and physiological disorders. Methods of making these compounds and crystalline forms SA-1 and N-2 are also described in the present invention. 2. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of the crystalline form according to .3. A method of treating a disorder which is created by or is dependent upon decreased availability of norepinephrine claim 1 , dopamine claim 1 , or serotonin claim 1 , said method comprising: administering to a patient in need of such treatment a therapeutically effective amount of a crystalline form according to or a pharmaceutically acceptable salt thereof.4. The method according to claim 3 , wherein the disorder is selected from the group consisting of attention deficit hyperactivity disorder (ADHD) claim 3 , cognition impairment claim 3 , anxiety disorders claim 3 , generalized anxiety disorder (GAD) claim 3 , panic disorder claim 3 , bipolar disorder or manic depression or manic-depressive disorder claim 3 , obsessive compulsive disorder (OCD) claim 3 , posttraumatic stress disorder (PTSD) claim 3 , acute stress disorder claim 3 , social phobia claim 3 , simple phobias claim 3 , pre-menstrual dysphoric disorder (PMDD) claim 3 , social anxiety disorder (SAD) claim 3 , major depressive disorder (MDD) claim 3 , postnatal depression claim 3 , dysthymia claim 3 , depression associated with Alzheimer's disease claim 3 , Parkinson's disease claim 3 , or psychosis claim 3 , supranuclear palsy claim 3 , eating disorders claim 3 , obesity claim 3 , anorexia nervosa claim 3 , bulimia nervosa claim 3 , binge eating disorder claim 3 , diabetes claim 3 , ischemic diseases claim 3 , pain claim 3 , substance abuse disorders claim 3 , chemical dependencies claim 3 , ...

VIDEO RECOMMENDATION METHOD AND APPARATUS

The present disclosure provides a video recommendation method and a video recommendation apparatus, a computer device and a storage medium. The video recommendation method includes: acquiring a target short video; identifying, from candidate long videos, a target long video that the target short video is from based on a video fingerprint feature of the target short video and video fingerprint features of the candidate long videos; and recommending the target long video. 1. A video recommendation method , comprising:acquiring a target short video;identifying, from candidate long videos, a target long video that the target short video is from based on a video fingerprint feature of the target short video and video fingerprint features of the candidate long videos; andrecommending the target long video.2. The video recommendation method according to claim 1 , wherein recommending the target long video comprises:displaying a prompt message of the target long video on a playing page for playing the target short video, wherein the prompt information comprises at least one of an identifier of the target long video, a link of resources of the target long video, and an identifier of a long video set comprising the target long video.3. The video recommendation method according to claim 2 , further comprising:in response to detecting a target operation performed on the prompt message of the target long video, displaying a playing page for playing the target long video to play the target long video.4. The video recommendation method according to claim 2 , wherein displaying the prompt message of the target long video on the playing page for playing the target short video comprises:in response to detecting that the target short video is played in a full screen mode on the playing page, displaying a floating control on the playing page, wherein the floating control is configured to display the prompt message of the target long video and to respond to the target operation ...

CRYSTALLINE FORM OF 6-[(4S)-2-METHYL-4-(2-NAPHTHYL)-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL]PYRIDAZIN-3-AMINE

The present disclosure generally relates to a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. The present disclosure also generally relates to pharmaceutical compositions comprising the crystalline form, as well of methods of using a crystalline form in the treatment of depression and other conditions and methods for obtaining such crystalline form. 2. The method of wherein the mammal is a human. This divisional application claims the benefit of U.S. Ser. No. 13/845,919 filed Mar. 18, 2013, now allowed, which is a divisional application which claims the benefit of U.S. Ser. No. 12/995,771 filed Dec. 2, 2010, now U.S. Pat. No. 8,445,494, which is the 371 National Stage of International Application No. PCT/US2009/046256 filed Jun. 4, 2009 which claims the benefit under 35 U.S.C. §119(e) of 61/058,717 filed Jun. 4, 2008, now expired, which are herein incorporated by reference in their entirety.The present disclosure generally relates to a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. The present disclosure also generally relates to a pharmaceutical composition comprising a crystalline form, as well of methods of using a crystalline form in the treatment of depression and other conditions and methods for obtaining such crystalline form.Major depression (unipolar depression) is a condition of high prevalence and very high global burden. The prevalence of the disease in the US was estimated at over 6% in a twelve month period and 16% over a lifetime (See, Kessler R. C. et al., “Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication”, 62:617-627 (2005)). According to the World Health Organization, the impact of the disorder is high with depression being the fourth leading cause of disease burden (See, Ustun, J. L. et al., “Global burden of depressive disorders in the year 2000. Psychiatry, 184:386-392 ( ...

POLYMER, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC EL DISPLAY DEVICE, AND ORGANIC EL LIGHTING DEVICE

The object of the present invention is to provide a polymer capable of being insolubilized at a low temperature in a short time, having a high hole injecting and transporting ability and a high durability, and a composition for organic electroluminescent element comprising the polymer. The polymer of the present invention comprises a specific crosslinkable group. 5. The polymer according to claim 1 , which has a weight-average molecular weight (Mw) of 20 claim 1 ,000 or more claim 1 , and a degree of dispersion (Mw/Mn) of 2.5 or less.6. A composition for organic electroluminescent element claim 1 , which comprises the polymer of .7. An organic electroluminescent element comprising a substrate claim 6 , an anode and a cathode provided on the substrate claim 6 , and an organic layer provided between the anode and the cathode claim 6 , wherein the organic layer contains a layer formed by a wet film formation method using the composition for organic electroluminescent elements of .8. The organic electroluminescent element according to claim 7 , wherein the layer formed by a wet film formation method is at least one of a hole injection layer and a hole transport layer.9. The organic electroluminescent element according to claim 7 , which comprises a hole injection layer claim 7 , a hole transport layer and a light-emitting layer between the anode and the cathode claim 7 , wherein the hole injection layer claim 7 , the hole transport layer claim 7 , and the light-emitting layer are all formed by a wet film formation method.10. An organic EL display device comprising the organic electroluminescent element of .11. An organic EL lighting device comprising the organic electroluminescent element of . The present invention relates to a polymer, particularly to a polymer useful as a hole injection layer and a hole transport layer of organic electroluminescent element, and to a composition for organic electroluminescent element containing the polymer. The invention also relates ...

POSITIONING STUD FOR RADIOACTIVE THERAPY AND STEREOTACTIC DEVICE

A positioning stud for radioactive therapy includes a stud rod, a stud tip, and an insulating component. The insulating component is connected between the stud rod and the stud tip, and is used to prevent contact between the stud rod and the stud tip. 1. A positioning stud for radioactive therapy , comprising: a stud rod , a stud tip , and an insulating component; andthe insulating component being connected between the stud rod and the stud tip, and being configured to prevent contact between the stud rod and the stud tip.2. The positioning stud for radioactive therapy according to claim 1 , wherein the insulating component is an electrically insulating spacer.3. The positioning stud for radioactive therapy according to claim 2 , wherein the electrically insulating spacer is connected to the stud rod by bonding claim 2 , welding or plug-in type claim 2 , and the electrically insulating spacer is connected to the stud tip by bonding claim 2 , welding or plug-in type.4. The positioning stud for radioactive therapy according to claim 2 , whereineach of two opposite surfaces of the electrically insulating spacer are provided with a first connecting portion,a surface of the stud rod connected to the electrically insulating spacer is provided with a second connecting portion correspondingly, and a surface of the stud tip connected to the electrically insulating spacer is provided with a second connecting portion correspondingly, andthe second connecting portion on the stud rod is connected to a corresponding first connecting portion on the electrically insulating spacer, and the second connecting portion on the stud tip is connected to a corresponding first connecting portion on the electrically insulating spacer.5. The positioning stud for radioactive therapy according to claim 4 , wherein the first connecting portion is a raised step and/or a recess hole claim 4 , and the second connecting portion is a corresponding recess hole and/or a corresponding raised step.6. The ...

Previewing impacted entities in automated device definitions

Various examples are described for defining automations for client devices enrolled with a management service. A computing environment can cause one or more user interfaces to be shown in a display of an administrator device that include at least one field for generating an automation that includes a trigger, a condition, and an action to automatically be performed when the condition is satisfied. The trigger defines a time at which the management service compares the condition to device profiles generated for client devices enrolled with the management service. The user interface can forecast a number of client devices that will be affected or subject to an automation, and can display results of the automation as it is executed in real time.

TECHNIQUES FOR IMPROVED LOW DIELECTRIC CONSTANT FILM PROCESSING

A method may include providing a substrate having, on a first surface of the substrate, a low dielectric constant layer characterized by a layer thickness. The method may include heating the substrate to a substrate temperature in a range of 200° C. to 550° C.; and directing an ion implant treatment to the low dielectric constant layer, while the substrate temperature is in the range of 200° C. to 550° C. As such, the ion implant treatment may include implanting a low weight ion species, at an ion energy generating an implant depth equal to 40% to 175% of the layer thickness.

Crystalline form of methyl ((1s)-1-(((2s)-2-(5-(4'-(2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1h-imidazol-5-yl)-4-biphenylyl)-1h-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt

The present disclosure generally relates to a crystalline form of methyl ((1S)-1-(((2S>2-(5-(4'-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)- 1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt. The present disclosure also generally relates to a pharmaceutical composition comprising a crystalline form, as well of methods of using a crystalline form in the treatment of Hepatitis C and methods for obtaining such crystalline form.

Crystalline form of methyl ((1S)-1-((25)-2-(5-(4'-(2-((25)-1((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt

The present disclosure generally relates to a crystalline form of methyl ((1S)-1-(((2S)-2-(5-(4′-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt. The present disclosure also generally relates to a pharmaceutical composition comprising a crystalline form, as well of methods of using a crystalline form in the treatment of Hepatitis C and methods for obtaining such crystalline form.

Crystalline form of methyl ((1s)-1-(((2s)-2-(5-(4'-(2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt

The present disclosure generally relates to a crystalline form of methyl ((1S)-1-(((2S>2-(5-(4'-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-

Hepatitis C Virus Inhibitors

The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.

Fuel cell pack fixing structure with damping function

本实用新型涉及燃料电池技术领域，尤其是一种具备减震功能的燃料电池组固定结构，包括安装板，所述安装板正上方设有支撑板，所述支撑板底面四角均竖直固定有伸缩杆，每个所述伸缩杆表面均套装有第一减震弹簧，所述移动板两侧面中部均固定有移动块，每个所述长条卡槽内均固定有穿过通孔的滑杆，所述滑杆上套装有两个第二减震弹簧，所述移动板顶面连接有三个燃料电池本体，所述安装板上设有连接机构。本实用新型可以使燃料电池本体免于受到震动的伤害，延长了燃料电池本体的使用寿命。

Crystalline form of methyl ((1s)-1-(((2s)-2-(5-(4'-(2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1h-imidazol-5-yl)-4-biphenylyl)-1h-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt

The present disclosure relates to a crystalline form of methyl ((1S)-1-(((2S>2-(5-(4'-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt. The disclosure also relates to a pharmaceutical composition comprising a crystalline form, as well of methods of using a crystalline form in the treatment of Hepatitis C and methods for obtaining such crystalline form.

Crystalline form of 6-[(4s)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine

The present disclosure generally relates to a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. The present disclosure also generally relates to pharmaceutical compositions comprising the crystalline form, as well of methods of using a crystalline form in the treatment of depression and other conditions and methods for obtaining such crystalline form.

Process for the preparation of N,N-dicyclopropyl-4-(1,5-dimethyl-1H-pyrazol-3-ylamino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide

The invention relates to an improved process for synthesizing N,N-dicyclopropyl-4-(1,5-dimethyl-1H-pyrazol-3-ylamino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide of the formula: (I) Compound (I) is currently in clinical trials for the treatment of myeloproliferative disorders, such as polycythaemia vera, thrombocythaemia and primary myelofibrosis.

The use of ginkgo biloba extract in preparation of a composition for lowering cholesterol

Storage box of hand tool

Composition from ginkgo biloba leaves, preparation and uses

The invention relates to an inproved extract composition from Ginkgo biloba leaves and said compositions comprise some new active component. The invention also provides methods of preparation of such compositions and single component and various uses of such compositions.

PROCESS FOR THE PREPARATION OF N,N-DICYCLOPROPYL-4-(1,5-DIMETHYL-1H-PYRAZOL-3-YLAMINO)-6-ETHYL-1-METHYL-1,6-DIHYDROIMIDAZO[4,5-d]PYRROLO[2,3-b]PYRIDINE-7-CARBOXAMIDE

The invention relates to an improved process for synthesizing N , N -dicyclopropyl-4-(1,5-dimethyl-1 H -pyrazol-3-ylamino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide of the formula: (I) Compound (I) is currently in clinical trials for the treatment of myeloproliferative disorders, such as polycythaemia vera, thrombocythaemia and primary myelofibrosis.

Building supporting frame

Computer memory card connector

Lectin-macromolecule carrier coupling complex for separating glycosylated exosome in clinical sample

The present invention relates to a lectin-macromolecular carrier coupling complex for separating glycosylated exosomes from a clinical sample, which comprises a macromolecular carrier and lectins coupled to the outer side of the macromolecular carrier. The complex may simply, conveniently, rapidly, and accurately separate glycosylated exosomes from a clinical sample with a high separation efficiency and a good repeatability; and the separated exosomes are intact in morphology without rupturing or cracking, may be directly used for liquid detection of glycosylated exosomes, or directly used for immunology-related detection, or directly used for gene detection or analysis after extracting related nucleic acids from the exosomes.

Mono-lysine salts of azole compounds

Mono-lysine salts of triazole compounds having a secondary or tertiary hydroxy group are provided. More particularly, the new water-soluble triazole antifungal mono-lysine salt compounds, or solvates thereof, are provided having the general formula I: wherein A in formula I represents the non-hydroxy portion of a triazole antifungal compound of the type containing a secondary or tertiary hydroxyl group. R and R1 in formula I can each be a hydrogen atom or an alkyl group having one to six carbon atoms. The novel water-soluble azole compounds are useful for the treatment of fungal infections and can be administered orally, topically and parenterally.

Crystalline form of methyl ((1s)-1-(((2s)-2-(5-(4'-(2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1h-imidazol-5-yl)-4-biphenylyl)-1h-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt

The present disclosure generally relates to a crystalline form of methyl ((1S)-1-(((2S>2-(5-(4'-(2-((2S)-1-((2S)-2--((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt. The present disclosure also generally relates to a pharmaceutical composition comprising a crystalline form, as well of methods of using a crystalline form in the treatment of Hepatitis C and methods for obtaining such crystalline form.

Touch substrate, method for manufacturing the same, and touch display device

A touch substrate, a method for manufacturing a touch substrate, and a touch display device are provided. The touch substrate includes: a base substrate having a first surface; a first over coat layer on the first surface; a first touch electrode on the first over coat layer; and a second over coat layer on the first touch electrode, wherein the first touch electrode is located between the first over coat layer and the second over coat layer, and the second over coat layer covers at least the first touch electrode, and wherein an area of at least one of the first over coat layer and the second over coat layer is less than an area of the first surface in the touch area.

Systems and methods for extracting diagnostic and resolution procedures from heterogenous information sources

A non-transitory computer readable medium (26) stores instructions executable by at least one electronic processor (20) to perform a medical device servicing method (100) for a medical device (12), including: deriving a representation (36) of a base diagnostic procedure for diagnosing a malfunction of the medical device from one or more service manuals (32); analyzing historical service records (34) to extract diagnostic procedures applied in historical service cases for diagnosing the malfunction of the medical device; adding the extracted diagnostic procedures to the representation of the base diagnostic procedure to generate an updated representation (40) of the base diagnostic procedure; calculating likelihood of success scores (42) for each path of the updated representation of the base diagnostic procedure based on statistics of outcomes of the historical service cases; and outputting the updated representation of the base diagnostic procedure on an electronic processing device (18) operable by a service engineer (SE).

Crystalline form of 6-ý(4s)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl¨pyridazin-3-amine

Use of ginkgolic acids in preparing biotic pesticide for killing snails and preventing schistomiasis

The invention provides a new use of 6-alkylsalicylic acids known as ginkgolic acids in preparing biotic pesticide. Particularly, it is directed to the use of ginkgolic acids for killing snails and preventing schistomiasis. The invention makes the most of ginkgo leaves. The invention also relates to a killing-snail agent comprising ginkgolic acids, by which high activity and low toxicity can be achieved. The invention provides furthermore a pesticidal composition for killing snails, which comprises 20-50% ginkgolic acids, 0.1-10%niclosamide, 0.01-1%copper sulfate, and adjuvants. The composition can kill effectively Oncomelania snails as the only host of schistomiasis in china, thus controlling schistomiasis.

Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione

The instant invention provides crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione; processes for the production of such crystalline materials; pharmaceutical compositions comprising such crystalline materials; and methods of treating HIV or AIDS with such crystalline materials or such pharmaceutical compositions.

Time series anomaly ranking

In an example embodiment, a machine-learned model is trained to rank anomaly points in time series data. The model is capable of being applied in parallel to many different time series simultaneously, allowing for a scalable solution for large scale online networks. The model outputs a ranking score for an input anomaly and allows for ranking of anomalies not just in the same time series but anomalies across multiple time series as well. This ranking can then be used to determine how best to present the ranked anomalies to users in a graphical user interface.

System and method for improved spare part search for maintenance services using topic modelling

A recommendation method (200) includes: querying a knowledge base (130) of maintenance cases using the text query to retrieve a ranked list (138) of maintenance cases relating to a text query; performing topic modeling (140) on the maintenance cases of the ranked list of maintenance cases to group the maintenance cases into N topics; for each topic, ranking the replaced part identifiers associated to the maintenance cases grouped into that topic to generate a ranked replaced part identifiers list (142) for that topic; displaying summarizations (144) of the N topics on the display of the user interface and receiving a selection of a selected topic of the N topics via the user interface device; and displaying a list (150) of recommended parts for replacement comprising at least a top portion of the ranked replaced part identifiers list for the selected topic on the display of the user interface device.

Method and apparatus for resource transmission

本發明揭露了一種資源傳輸方法及裝置。所述方法包括：第一即時通訊IM用戶端接收第二IM用戶端發送的多媒體檔，播放所述多媒體檔，在播放多媒體檔的播放介面中顯示資源傳輸控制項，當監測到使用者對資源傳輸控制項的操作時，將第一IM用戶端對應的資源發送給第二IM用戶端。藉由本方法，當第一IM用戶端接收到了第二IM用戶端所發送的多媒體檔並進行播放後，將在播放該多媒體檔的播放介面中顯示資源傳輸控制項，從而，使用第一IM用戶端的使用者要想發起資源傳輸操作，無需進行介面的切換，只需對當前的播放介面中所顯示出的資源傳輸控制項進行操作，就可實現向第二IM用戶端傳輸資源。顯然，這種方式有效簡化了操作過程，便於使用者操作。

Inhibidor de integrina y usos de este

Refiere a formas cristalinas de sales de inhibidores de integrina, las cuales son sales del acido (S)-4-((2-metoxietil)(4-(5,6,7,8-tetrahidro-1,8-naftiridin-2-il)butil)amino)-2-(quinazolin-4-ilamino)butanoico, sales de fosfato o fumarato. Dichas formas se caracterizan por presentar un patron de difraccion de polvo de rayos X (XRPD) con picos en angulos 2-theta de 4.31-6.76 grados; picos endotermicos de 88.3 °C - 197.6 °C determinados por calorimetria diferencial de barrido (DSC); y una perdida de peso de aproximadamente 13.02 % despues de calentarse a 26.0°C - 125.0°C determinada por un analisis termogravimetrico (TGA). Asimismo, se mencionan metodos para la preparacion de las formas cristalinas; y composiciones farmaceuticas a base de dichas formas y un portador o excipiente farmaceuticamente aceptables, para el tratamiento de enfermedades fibroticas.

Identifying the cause of a problem with a medical imaging device

:A mechanism for generating a technical description of a fault of a medical imaging device. A questionnaire for a respondent is tailored based on at least a user profile of the respondent. The response of the respondent to the questionnaire is used to identify features of the fault, which is in turn used to generate and output the fault description.

Culture of Eupenicillium brefeldianum

Certain novel 1H-cycloundeca[1,2-b:5,6-b']biscyclohepta(b)pyran analogs are useful as antitumor agents.

Use of gp73 inhibitor in preparation of medicine for treating diabetes

Monolysinsalze von azolverbindungen

Vehicle body contour-based derailment detection method for rail vehicle

A vehicle body contour-based derailment detection method for a rail vehicle, including: measuring distances between measuring points and rails through a range finder mounted on an underframe of a vehicle body, and calculating a transverse displacement of the current vehicle body in a vehicle body coordinate system; measuring an inclination angle of the current vehicle body in the vehicle body coordinate system through an inclination sensor on the vehicle body; with reference to a size of the vehicle body and distribution positions of the measuring points, as well as the transverse displacement of the current vehicle body in the vehicle body coordinate system and the inclination angle of the vehicle body in the vehicle body coordinate system, obtaining a dynamic outer contour of the vehicle body in the vehicle body coordinate system and converting it into a dynamic outer contour in the rail coordinate system.

Thermally detachable multilayer compositions bonded with thermoplastic primers

Multilayer compositions include a substrate having a surface energy of 35 dynes/cm or greater; one or more thermoplastic primer layers comprising 55 wt% to 100 wt% of a maleic anhydride grafted chlorinated polyolefin and a glass transition temperature in the range of 50 °C to 120 °C; and one or more thermoset adhesive layers.

Sequential plasma and thermal treatment

Methods of manufacturing memory devices are provided. The methods improve the quality of a selectively deposited silicon-containing dielectric layer. The method comprises selectively depositing a silicon-containing dielectric layer in a recessed region of a film stack. The selectively deposited silicon-containing dielectric layer is then exposed to a high-density plasma annealed at a temperature greater than 800 ℃ to provide a silicon-containing dielectric film having a wet etch rate of less than 4 Å/min.

System and method for automated or semi-automated identification of malfunction area(s) for maintenance cases

A method (100) of automated identification of one or more malfunction areas of a set (S) of malfunction areas for a service case in which a medical device (12) is serviced includes: generating an output probability vector (40) of probabilities for the set of malfunction areas of the medical device by operations including applying at least one classifier (42, 46) to at least one of (1) text descriptions of parts ordered for the service case and/or (2) a text description of the service case; and displaying a list (56) of one or more most probable malfunction areas for the service case wherein the one or more most probable malfunction areas are the one or more most malfunction areas of the set of malfunction areas having highest probability in the output probability vector.

Maintenance history visualizer to facilitate solving intermittent problems

A non-transitory computer readable medium (107, 127) stores instructions readable and executable by at least one electronic processor (101, 113) operatively connected with a display (105) and at least one user input device (103) to perform a device service support method (200). The method includes: identifying attribute values (120) for attributes (122) of a plurality of previous service cases (124) from a service log (130); identifying a set of relevant service cases (128) from the plurality of previous service cases by comparing the identified attribute values for the previous service cases with attribute values for a current service case (126) using a comparison metric (132) and a relevance threshold (134); plotting, on the display, a timeline (150) of relevant service cases (140) of the set of relevant service cases as a function of calendar dates of the relevant service cases; providing a relevance graphical user interface (GUI) dialog (160) for user adjustment of the relevance threshold via the at least one user input device; and responsive to user adjustment of the relevance threshold via the relevance GUI dialog, repeating the identifying and plotting to dynamically update the plotted timeline on the basis of the user adjustment of the relevance threshold.

Thermally triggered primer and thermosetting adhesive multilayer composition for detachment of ev battery pack

Methods may include detaching a battery pack adhered to a substrate by a multilayer composition, including: heating the multilayer composition to a detachment temperature above 60℃, the multilayer composition comprising one or more thermoplastic primer layers having a transition temperature in the range of 60 ℃ to 120 ℃, and one or more thermoset adhesive layers; and separating one or more layers of the multilayer composition to detach the battery pack from the substrate, wherein the substrate has a surface energy of 35 dynes/cm or greater.

Integrin inhibitor and uses thereof

Provided herein are integrin inhibitors, compositions thereof, and methods of their uses. Crystalline forms of salts of the inhibitors are also described, along with methods of preparing the crystalline forms. X-ray powder diffraction data, thermogravimetric analysis, and differential scanning calorimetry data are provided for the crystalline forms. The integrin inhibitors are useful for treatment of, inter alia, fibrotic diseases.

Two-dimensional embedding of a hierarchical menu for easy navigation

An apparatus (10) for navigating a hierarchical electronic questionnaire (12) includes at least one electronic processor (20) programmed to: provide (102) a user interface (UI) (27) via which: at least a portion of the hierarchical electronic questionnaire is presented on a display device (24) represented as a tree-based questionnaire map (30) with a plurality of nodes (32) connected by a plurality of branches (34), the nodes of the plurality of nodes corresponding to questions; a user input is received, via at least one user input device (22), indicative of a selection of at least one of the nodes; and the question corresponding to the selected node is displayed and a user input indicative of an answer to the question corresponding to the selected node is received via the at least one user input device; and populate (104) one or more nodes other than the selected node based on the selected node and/or the answer to the question corresponding to the selected node.

Parts co-replacement recommendation system for field servicing of medical imaging systems

At a service device (102), a user interface (106) is provided via which a user submits an order request (117) to order a requested part (X) via the at least one user input device (103). Co-replacement information (116) for the requested part (X) is identified using a co-replacements database (114), and is displayed on the display. For example, a second part (Y) commonly co-replaced with requested part (X) may be identified and recommended for replacement with part (X); or, if two parts (X) and (Y) are ordered then the co-replacement information may be to recommend ordering only one of these parts. At a server hosting the database (114), the order request is received from a service device and the co-replacement information (116) for the requested part is generated using the co-replacements database (114), and the co-replacement information is sent to the service device.

水流發電機之弧形柱垂直軸式渦輪裝置

Isolated antigen binding protein and use thereof

An isolated antigen binding protein, which includes at least one CDR of a heavy chain variable region and at least one CDR of a light chain variable region and a method to encode an isolated nucleic acid molecule. A vector with the nucleic acid molecule. A cell with the nucleic acid molecule. A pharmaceutical composition with the isolated antigen binding protein. A method for preventing, alleviating or treating a CS-related disease or disorder. A method for detecting C5 in a sample.

Lectin-macromolecule carrier coupling complex for separating glycosylated exosome in clinical sample

Information processing device, information processing method, information processing system, robot system, and program

An information processing device ( 10 ) includes: a first acquisition section ( 12 ) that acquires input data; a generation section that generates, from the input data, reservoir input data which is to be input to a quantum reservoir ( 20 ) having a plurality of layers of sub-reservoirs; a second acquisition section ( 12 ) that acquires an output result of the quantum reservoir to which the reservoir input data has been input; and an output data generation section ( 14 ) that generates output data with reference to the output result.

Formas cristalinas, composições que contêm as mesmas, e métodos de uso das mesmas

ormas cristalinas, composições que contêm as mesmas, e métodos de uso das mesmas. a presente invenção se refere a formas cristalinas do composto da estrutura (i) ou um sal de sulfato, um sal de hemissulfato, ou um sal de sulfato de hidrogênio do mesmo, ou um hidrato do mesmo. também são divulgados sais de sulfato, sais de hemissulfato e sais de sulfato de hidrogênio do composto da fórmula (i), e hidratos do mesmo. (i)

Composition for inhibiting respiratory virus and respiratory virus prevention and treatment method

Composition for inhibiting respiratory virus and respiratory virus prevention and treatment method

The present disclosure specifically relates to a composition for inhibiting respiratory viruses and a method for preventing and treating a respiratory virus. Respiratory viral infections are extremely common clinically, yet the current therapeutic drugs for viral infections cannot meet the treatment needs. The present disclosure provides an inhalant for inhibiting respiratory viruses and adopts a method of inhaling high-temperature acetic acid steam for prevention and treatment. Acetic acid in the high-temperature steam can release hydrogen ions to inactivate viruses in the respiratory tract, so as to prevent the onset of the disease and provide a therapeutic effect. In addition, the composition can be used to inhibit fungi and bacteria in vitro and prevent skin diseases and respiratory diseases caused by bacteria and fungi. The prevention and treatment method of the present disclosure is easy to implement and has low costs and important clinical application value.

Context-aware interactive exploration of maintenance service reports

A non-transitory computer readable medium (107, 127) stores a database of historical service reports (130) on previous service cases for medical devices (120); and instructions readable and executable by at least one electronic processor (101, 113) to receive a query providing details of a current service case for a medical device undergoing service; retrieve, from the database and based on the query, one or more historical service reports; analyze the retrieved historical service reports to identify information of the retrieved historical service reports belonging to facets (132) of a set of facets; and display, on a display device (105), a user interface (UI) (138) configured to present a set of facet windows (136) corresponding to the set of facets with each facet window configured to present a summary of the information identified as belonging to the corresponding facet.

Crystalline forms of squalamine

This disclosure provides crystalline polymorphs of squalamine phosphate, methods of making the same, and methods of treatment using the same.

Maintenance history visualizer to facilitate solving intermittent problems

A non-transitory computer readable medium (107, 127) stores instructions readable and executable by at least one electronic processor (101, 113) operatively connected with a display (105) and at least one user input device (103) to perform a device service support method (200). The method includes: identifying attribute values (120) for attributes (122) of a plurality of previous service cases (124) from a service log (130); identifying a set of relevant service cases (128) from the plurality of previous service cases by comparing the identified attribute values for the previous service cases with attribute values for a current service case (126) using a comparison metric (132) and a relevance threshold (134); plotting, on the display, a timeline (150) of relevant service cases (140) of the set of relevant service cases as a function of calendar dates of the relevant service cases; providing a relevance graphical user interface (GUI) dialog (160) for user adjustment of the relevance threshold via the at least one user input device; and responsive to user adjustment of the relevance threshold via the relevance GUI dialog, repeating the identifying and plotting to dynamically update the plotted timeline on the basis of the user adjustment of the relevance threshold.

Parts co-replacement recommendation system for field servicing of medical imaging systems

At a service device (102), a user interface (106) is provided via which a user submits an order request (117) to order a requested part (X) via the at least one user input device (103). Co-replacement information (116) for the requested part (X) is identified using a co-replacements database (114), and is displayed on the display. For example, a second part (Y) commonly co-replaced with requested part (X) may be identified and recommended for replacement with part (X); or, if two parts (X) and (Y) are ordered then the co-replacement information may be to recommend ordering only one of these parts. At a server hosting the database (114), the order request is received from a service device and the co-replacement information (116) for the requested part is generated using the co-replacements database (114), and the co-replacement information is sent to the service device.

System and method for improved spare part search for maintenance services using topic modelling

A recommendation method (200) includes: querying a knowledge base (130) of maintenance cases using the text query to retrieve a ranked list (138) of maintenance cases relating to a text query; performing topic modeling (140) on the maintenance cases of the ranked list of maintenance cases to group the maintenance cases into N topics; for each topic, ranking the replaced part identifiers associated to the maintenance cases grouped into that topic to generate a ranked replaced part identifiers list (142) for that topic; displaying summarizations (144) of the N topics on the display of the user interface and receiving a selection of a selected topic of the N topics via the user interface device; and displaying a list (150) of recommended parts for replacement comprising at least a top portion of the ranked replaced part identifiers list for the selected topic on the display of the user interface device.

System and method for improved spare part search for maintenance services using topic modelling

A recommendation method ( 200 ) includes: querying a knowledge base ( 130 ) of maintenance cases using the text query to retrieve a ranked list ( 138 ) of maintenance cases relating to a text query; performing topic modeling ( 140 ) on the maintenance cases of the ranked list of maintenance cases to group the maintenance cases into N topics; for each topic, ranking the replaced part identifiers associated to the maintenance cases grouped into that topic to generate a ranked replaced part identifiers list ( 142 ) for that topic; displaying summarization ( 144 ) of the N topics on the display of the user interface and receiving a selection of a selected topic of the N topics via the user interface device; and displaying a list ( 150 ) of recommended parts for replacement comprising at least a top portion of the ranked replaced part identifiers list for the selected topic on the display of the user interface device.

High-toughness ultrahigh-strength steel and manufacturing method therefor

The present application discloses a high-toughness ultrahigh-strength steel and a manufacturing method thereof, and belongs to the technical field of metal materials. The present application is intended to solve the problem that the existing low-alloy ultrahigh-strength steel has poor toughness and poor hardenability. The high-toughness ultrahigh-strength steel includes the following elements in mass percentages: C: 0.27% to 0.35%; Si: 1.10% to 1.70%; Mn: 0.70% to 1.10%; Cr: 1.00% to 1.40%; Ni: 0.10% to 0.50%; Mo: 0.05% to 0.50%; W: 0.05% to 0.10%; Nb: 0.01% to 0.04%; and iron and unavoidable impurities: the balance. The high-toughness ultrahigh-strength steel of the present application has excellent strength, toughness and hardenability.

CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF

Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1h-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione

The instant invention provides crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione; processes for the production of such crystalline materials; pharmaceutical compositions comprising such crystalline materials; and methods of treating HIV or AIDS with such crystalline materials or such pharmaceutical compositions.

Crystalline forms, compositions containing same, and methods of their use

Disclosed are crystalline forms of the compound of the following structure (I): or a sulfate salt, a hemi-sulfate salt, or a hydrogen sulfate salt thereof, or a hydrate thereof. Also disclosed are sulfate salts, hemi-sulfate salts, and hydrogen sulfate salts of the compound of formula (I), and hydrates thereof.

Ion implantation for reduced hydrogen incorporation in amorphous silicon

Exemplary methods of semiconductor processing may include forming a layer of amorphous silicon on a semiconductor substrate. The layer of amorphous silicon may be characterized by a first amount of hydrogen incorporation. The methods may include performing a beamline ion implantation process or plasma doping process on the layer of amorphous silicon. The methods may include removing hydrogen from the layer of amorphous silicon to a second amount of hydrogen incorporation less than the first amount of hydrogen incorporation.

多功能電磁爐裝置

金属亜鉛二次電池用電解液

【課題】亜鉛金属負極の高度な反応可逆性を実現できる、亜鉛二次電池用の新規水系電解液を提供することを課題とする。【解決手段】溶媒として水を含有する亜鉛二次電池用電解液であって、ｐＨ７以下のｐＨを有し、かつ前記電解液の還元分解電位以上の亜鉛析出溶解電位を有する、電解液。【選択図】なし

Multi-criteria fair queueing of alerts

A method (100) of generating a ranked list (42) of alerts (30) from files (32) of electronic devices (12) includes: applying predictive models (34) to data of the files to generate maintenance alerts for the electronic devices; assigning discrete values for a set of criteria (36) to each maintenance alert whereby the maintenance alert has a share computed as a product of the assigned discrete values; performing a credit-based queuing process (38) to assign the maintenance alerts to slots of a ranked list, wherein in the credit-based queuing process the maintenance alerts accumulate credits in accord with the shares computed for the respective maintenance alerts; and displaying, on a display device (24) operatively connected with the at least one electronic processor, the maintenance alerts as the ranked list in accordance with the assignments of the maintenance alerts to the slots of the ranked list.

Automatic construction of fault-finding trees

A non-transitory computer readable medium (107, 127) stores instructions executable by at least one electronic processor (101, 113) to perform a method (200, 300) of generating a recommendation engine for recommending actions during performance of a fault-finding task. The method comprises: converting a collection of historical fault-finding process sequences (140) into a fault-finding tree (130) having nodes (132), action edges (135) and outcome edges (137) connecting the nodes. The action edges are labeled with actions of the historical fault-finding process sequences and the outcome edges are labeled with outcomes of the historical fault-finding process sequences. The nodes include terminal nodes (133) labeled with root causes or solutions identified by the historical fault-finding process sequences. A visualization (142) of the fault- finding tree is provided on a user interface (UI) (120) on a service device (102) operable by a field service engineer (FSE).

Primer composition in thermally detachable multilayer structure bonded with thermosetting adhesives

Thermoplastic primer compositions may include a high surface energy thermoplastic resin having a surface energy of 37 dynes/cm or greater, at a percent by weight (wt%) of 55 wt%to 90 wt%; a low surface energy thermoplastic resin having a surface energy of less than 37 dynes/cm, at 10 wt%to 45 wt%; wherein the thermoplastic primer composition has a glass transition temperature in the range of 60 ℃ to 120 ℃. Multilayer compositions may include a substrate having a surface energy of 37 dynes/cm or greater; a primer layer containing a thermoplastic primer composition; and one or more thermoset adhesive layers.

Multi-criteria fair queueing of alerts

A method (100) of generating a ranked list (42) of alerts (30) from files (32) of electronic devices (12) includes: applying predictive models (34) to data of the files to generate maintenance alerts for the electronic devices; assigning discrete values for a set of criteria (36) to each maintenance alert whereby the maintenance alert has a share computed as a product of the assigned discrete values; performing a credit-based queuing process (38) to assign the maintenance alerts to slots of a ranked list, wherein in the credit-based queuing process the maintenance alerts accumulate credits in accord with the shares computed for the respective maintenance alerts; and displaying, on a display device (24) operatively connected with the at least one electronic processor, the maintenance alerts as the ranked list in accordance with the assignments of the maintenance alerts to the slots of the ranked list.

Automatic construction of fault-finding trees

A non-transitory computer readable medium ( 107, 127 ) stores instructions executable by at least one electronic processor ( 101, 113 ) to perform a method ( 200, 300 ) of generating a recommendation engine for recommending actions during performance of a fault-finding task. The method comprises: converting a collection of historical fault-finding process sequences ( 140 ) into a fault-finding tree ( 130 ) having nodes ( 132 ), action edges ( 135 ) and outcome edges ( 137 ) connecting the nodes. The action edges are labeled with actions of the historical fault-finding process sequences and the outcome edges are labeled with outcomes of the historical fault-finding process sequences. The nodes include terminal nodes ( 133 ) labeled with root causes or solutions identified by the historical fault-finding process sequences. A visualization ( 142 ) of the fault-finding tree is provided on a user interface (UI) ( 120 ) on a service device ( 102 ) operable by a field service engineer (FSE).

Vehicle body contour-based derailment detection method for rail vehicle

A vehicle body contour-based derailment detection method for a rail vehicle, including: measuring distances between measuring points and rails through a range finder mounted on an underframe of a vehicle body, and calculating a transverse displacement of the current vehicle body in a vehicle body coordinate system; measuring an inclination angle of the current vehicle body in the vehicle body coordinate system through an inclination sensor on the vehicle body; with reference to a size of the vehicle body and distribution positions of the measuring points, as well as the transverse displacement of the current vehicle body in the vehicle body coordinate system and the inclination angle of the vehicle body in the vehicle body coordinate system, obtaining a dynamic outer contour of the vehicle body in the vehicle body coordinate system and converting it into a dynamic outer contour in the rail coordinate system.

Microwave cookware

Systems and methods for recommending diagnostic actions for medical device diagnostic tools

A database stores summaries of historical service cases. A request for assistance is received for a current service case for a medical device. A context of the current service case is identified based at least on the received request. Candidate filter value combinations are generated for a plurality of filters for use in searching the summaries of historical service cases. The candidate filter combinations are generated based on the identified context of the current service case. The candidate filter value combinations are simulated by filtering the database using the candidate filter combinations. A recommended combination of filter values or a recommended service action is identified based on the simulating. On a display device of an electronic processing device operable by a service engineer (SE), the recommended combination of filter values or recommended service action is output.

Crystalline forms of squalamine

This disclosure provides crystalline polymorphs of squalamine phosphate, methods of making the same, and methods of treatment using the same.