03-01-2013 дата публикации
Номер: US20130000378A1
Methods and devices for correcting sensing device signals, e.g., for point of care immunoassay devices. In one embodiment, the invention is to a method of correcting a signal in a sensing device, comprising the steps of: providing a sensing device comprising a sensor, a first electrical pad, a second electrical pad, and a continuous polymer layer contacting at least a portion of the first and second electrical pads; applying a potential across the first and second electrical pads; measuring an electrical property associated with the continuous polymer layer; determining a correction factor associated with the measured electrical property; and applying the correction factor to a signal generated by the sensor to produce a corrected signal. 1. A method of correcting a signal in a sensing device , comprising the steps of:providing a sensing device comprising a sensor, a first electrical pad, a second electrical pad, and a continuous polymer layer contacting at least a portion of the first and second electrical pads;applying a potential across the first and second electrical pads;measuring an electrical property associated with the continuous polymer layer;determining a correction factor associated with the measured electrical property; andapplying the correction factor to a signal generated by the sensor to produce a corrected signal.2. The method of claim 1 , wherein the correction factor is selected from the group consisting of an amperometric correction value claim 1 , a potentiometric correction value claim 1 , a coulombic correction value and a conductivity correction value.3. The method of claim 1 , wherein said sensor is selected from the group consisting of a pH sensor claim 1 , an oxygen sensor claim 1 , a carbon dioxide sensor claim 1 , a hematocrit sensor claim 1 , a glucose sensor claim 1 , a lactate sensor claim 1 , a creatinine sensor claim 1 , a sodium sensor claim 1 , a potassium sensor claim 1 , a chloride sensor claim 1 , a calcium sensor claim 1 , a ...
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