СПОСОБ ПОЛУЧЕНИЯ 2-(ФУРИЛ-2)-1,3-ДИОКСАНОВ

Использование: в качестве регулятора роста растений. Сущность изобретения: способ получения 2-(фурил-2)-1,3-диоксанов в ф-лы I где R1 = H или C1-C4 алкил, R2 = H, C1-C4 алкил, гидрокси C1-C4 алкил, R3, R4 и R5 = H или C1 - C4 алкил, взаимодействием многоатомного спирта, ф-лы II где R1 - R5 имеют вышуказанные значения, с фурфуролом при молярном соотношении компонентов, равном 1,1 : 1 соответственно, при комнатной температуре в присутствии 10% серной кислоты, взятой в количестве 10 мл на 1 моль фурфурола, с последующим охлаждением реакционной смеси и добавлением к ней воды в момент начала кристаллизации для выделения целевого продукта охлаждением из водной суспензии или эмульсии. 2 табл.

СПОСОБ ПОЛУЧЕНИЯ ФУРАНА ИЗ ФУРФУРОЛА

РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2016 142 388 A (51) МПК C07D 307/36 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2016142388, 26.03.2015 (71) Заявитель(и): ШЕЛЛ ИНТЕРНЭШНЛ РИСЕРЧ МААТСХАППИЙ Б.В. (NL) Приоритет(ы): (30) Конвенционный приоритет: 31.03.2014 EP 14162689.5 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 31.10.2016 R U (43) Дата публикации заявки: 03.05.2018 Бюл. № 13 (72) Автор(ы): ЛАНЖ Жан Поль Андре Мари Жозеф Гислен (NL), ВАДМАН Сипке Хидде (NL) (86) Заявка PCT: (87) Публикация заявки PCT: WO 2015/150241 (08.10.2015) A Адрес для переписки: 129090, Москва, ул. Б.Спасская, 25, строение 3, ООО "Юридическая фирма Городисский и Партнеры" R U (57) Формула изобретения 1. Способ получения фурана, при этом указанный способ включает стадии: контактирования фурфурола с катализатором декарбонилирования в реакторе декарбонилирования для получения газообразного потока продукта реакции декарбонилирования, содержащего фуран и угарный газ; контактирования указанного газообразного потока продукта реакции декарбонилирования с потоком растворителя, содержащим фурфурол; абсорбции по меньшей мере части фурана, присутствующего в газообразном потоке продукта реакции декарбонилирования, потоком растворителя для обеспечения содержащего фуран потока растворителя и газообразного потока, содержащего угарный газ; выделения фурана из содержащего фуран потока растворителя путем дистилляции для обеспечения первого потока фурана; и использования по меньшей мере части остающегося потока растворителя, содержащего фурфурол, в качестве по меньшей мере части фурфурола, подаваемого в реактор декарбонилирования. 2. Способ по п. 1, в котором поток после реакции декарбонилирования подвергается охлаждению и/или сжатию перед контактированием с потоком растворителя на стадии ii), при этом отделяется любая сконденсированная жидкость. 3. Способ по п. 1 или 2, в котором способ дополнительно включает стадии: Стр.: 1 ...

СПОСОБЫ БЕЗ ПРИМЕНЕНИЯ МЕТАЛЛИЧЕСКОГО КАТАЛИЗАТОРА И ГАЗООБРАЗНОГО ВОДОРОДА ДЛЯ СЕЛЕКТИВНОГО ВОССТАНОВЛЕНИЯ АЛЬДЕГИДНОЙ ГРУППЫ ДО МЕТИЛЬНОЙ ГРУППЫ В РАЗЛИЧНЫХ ЗАМЕЩЕННЫХ ФУРАНАХ

Изобретение относится к способу селективного восстановления альдегидной группы до метильной группы в замещенных фуранах с получением 5-метил-замещенных фуранов общей формулы (I), где R1 выбран из группы, состоящей из следующих: атом водорода, гидроксиметил, алкил, гидрокси-группа, альдегидная группа, атом галогена, сложноэфирная группа, карбоксил, нитро-группа, амино-группа, амид, замещенная амино-группа, алкокси/простоэфирные мостики, производные серы, производные фосфора, и арильная и гетероарильная функциональная группа; и R2 и R3 выбраны из группы, состоящей из следующих: атом водорода, алкил и арил, где указанный способ включает стадии: i) реакция аминного соединения и неорганического основания с замещенным фурфуралем формулы (II) в растворителе, с получением in situ соответствующего иминного соединения; ii) восстановление in situ сгенерированного имина со стадии (i) в основных условиях в растворителе, с получением 5-метил-замещенных фуранов общей формулы (I); iii) выделение метил-замещенных ...

Катализатор для декарбонилирования фурфурола в фуран

Изобретение касается каталитической химии. Цель изобретения - повышение активности катализатора. Для этого используют состав, содержащий, масД: палладий 0,8-1,2; цезий 0, носитель - остальное. В качестве носителя применяют уголь марки Сибу- нит. Этот катализатор по активности превосходит известный (без цезия) . В процессе декзрбонилировзния фурфурола достигается конверсия до 99% при выходе фурана 97-99% и стабильности в течение 387-397 ч, 1 табл.

Способ получения алкилпроизводных фурана

Способ получения сильвана

Способ получения сильвана

Способ получения 2,4-диалкилфуранов

CПOCOБ PAЗДEЛEHИЯ ЦИC-3-AMИHO-4-[2-(2-ФУPИЛ)-ЭT-1-ИЛ]-1-METOKCИKAPБOHИЛMETИЛ-AЗETИДИH-2-OHA HA EГO ЭHAHTИOMEPHЫE KOMПOHEHTЫ

Способ получения 2-метилфурана

Соли 3-метил-(5-фур-2)-ил-2,4-пентадиеновых кислот, обладающие антитранспирантной активностью

Изобретение относится к гетероциклическим соединениям, в частности к солям 3-метил-5(фУр-2 ил)-2, тадиеновых кислот ф-лы сн, R О СООМ Где R Н и М - ион Na, в виде Z, F или Е,Е изомера, R - СЬЦи И - ион Na в виде Z, Е или Е,Е изомера, R - Н и М - ион Ш4 в виде ZjE-изомера или R - СНЭ и М - ион NH4, в виде 2,С-изо- мера, которые обладают антитоанспи- рантной активностью,, Цель - выявление Сюлее активных соединений„ Получение ведут декарбоксилированием соответственно -карбокси 3 метил-5 (фур-2-ил)- и 4-карбокси 3-метил-Ь ...

Способ получения 2,5-диметилфурана

Способ получения -(гетероарилметил)дезоксинорморфинов или -норкодеинов

Способ получения 2-пропил-4,5-диалкилфуранов

Способ получения алкилфуранов

Способ получения алкилпроизводных 2-метилфурана

Способ получения 2-фурилметил/-6,7бензоморфанов

Способ получения 2-(фурилметил)-6,7-бензоморфанов

NEUE N-(HETEROARYLMETHYL)-DESOXYNORMORPHINE UND -NORCODEINE, DEREN SAEUREADDITIONSSALZE, VERFAHREN ZU DEREN HERSTELLUNG SOWIE DEREN VERWENDUNG ALS ARZNEIMITTEL

PROCESS FOR THE CONVERSION OF AN ALDEHYDE INTO AN ALKENE, ESPECIALLY OF PHENOLIC ALDEHYDES INTO CORRESPONDING ALKENES

ALKENE ALKYNE/CYCLOALKYLENE DERIVATIVES

Furan Flavouring Agents

... 1,156,480. Furan derivatives. R. FIRMENICH, G. FIRMENICH, R. E. FIRMENICH, and F. H. FIRMENICH, [trading as FIRMENICH & CIE.]. 2 May, 1966 [30 April, 1965; 18 April, 1966], No. 2381/69. Divided out of 1,156,472. Heading C2C. [Also in Division A2] 2-Isopropenyl-benzofuran.-According to the method described in J.A.C.S. 73, 754 (1951), 2-acetyl-benzofuran is reacted with methylmagnesium bromide to form 2-(2-hydroxyisopropyl)-benzofuran which is converted to its acetate. Pyrolysis of the acetate yields 2-isopropenyl-benzofuran of b.p. 81-83‹ C./0À001 mm. Hg. 7-Ethyl-benzofuran is prepared by the method described in J. Chem. Soc. 1920, 1534, but using o-ethylphenol instead of o-cresol. The MS. of the product thus obtained shows the following ion peaks with the relative intensities given within brackets: 131 (100%), 146 (38%) and 77 (10%). 2,7 - Dimethyl - benzofuran.-7 - Methylbenzofuran is subjected to a WILSMEYER reaction to form 7-methyl-benzofuran-2-aldehyde which is converted into 2,7-dimethylbenzofuran ...

Fluorene-based alternating copolymers and electroluminescence elements

Fluorene-based alternating copolymers to be used as light emitting materials of electroluminescent elements have the following formula (I). Electroluminescent elements may have an anode/luminescent layer/cathode structure, in which the fluorene-based alternating copolymer is used as light emitting materials of the luminescent layer, or may have a transporting and/or reflection layer added thereto, if necessary. where ```R and R' are each H, alkyl, cycloalkyl, aryl, alkoxy, cyclalkoxy or aryloxy ```X is H or CN ```Ar is alkylene or arylene, optionally substituted.

Improvements in or relating to photographic reproduction

... 2-Vinyl-4:5-diaryl-oxazoles are made by reacting acrylonitrile with benzoin or the appropriately-substituted benzoin, i.e. 4-dimethylamino, 4-diethylamino, 4-dimethylamino-41-chloro, and 4-dialkylamino-2-chloro where alkyl is methyl, ethyl, propyl and butyl. 2-Vinyl-quinoline and 3-vinyl-dibenzofuran are made by dehydration of the corresponding carbinols. 2-(a -hydroxyethyl)-9-methyl-carbazole and 3-(a -hydroxyethyl)-dibenzofuran are obtained by reducing the corresponding acetyl compounds with Raney nickel. 3-(a -hydroxyethyl)-9-ethyl-carbazole is prepared by reducing the 3-acetyl compound with sodium borohydride or treating the 3-aldehyde with methyl magnesium iodide. 3-Acetyl-9-ethyl-carbazole is obtained by N-ethylation with diethyl sulphate. 9-Isopropyl-carbazole - 3 - aldehyde and 9 -(p-methoxyphenyl)-carbazole-3-aldehyde are made by introduction of the aldehyde group with N-methyl-formanilide. 9-Isopropyl-carbazole is prepared from potassium carbazole and isopropyl bromide. 9-(p-methoxyphenyl ...

Methods for the synthesis of heteroaromatic compounds

PROCESS FOR THE SYNTHESIS OF 3-KETO-CYCLOPENTENE-5-OXY DERIVATIVES HAVING INSECTICIDE ACTIVITY

Process for the manufacture of furan

... 553,175. Catalysts. WILSON. C. L., and IMPERIAL CHEMICAL INDUSTRIES, Ltd. Nov. 7, 1941. No. 14348. [Class 1 (i)] [Also in Group IV] A nickel-containing solid catalyst for the hydrogenation of furfural to furane may be deposited on pumice &c. or used as wire clippings, or gauze, e.g. as an alloy of nickel and copper, and may be activated by heating to 550‹C. and subjecting to chlorine, subjecting alternately to hydrogen at 350‹C. and to air at 550‹C. until no hydrogen chloride is evolved. In an alternative preparation of catalyst, a nickel-aluminium alloy is granulated and reacted with hydrogen chloride, aluminium chloride sublimed off, and the catalyst oxidized with air at 550‹C. and reduced with hydrogen at 350‹C.

Heterocyclic ethanols

Novel compounds of the formulae where n is 0, 1, or 2, Y is an oxygen or sulphur atom, R4 is a halogen or C1- 5 alkyl radical, R1 is a C1- 5 alkylidene radical, R11 is a hydrogen atom or a C1- 5 alkyl radical, R6 is a hydrogen atom or an alkyl radical and R3 is a radical where R10 is a hydrogen atom or a hydroxy, C1- 5 alkoxy or benzyloxy radical with the proviso that R3 is not adjacent to the group and that when Y is oxygen the R3 and groups are not in a 2,4-position to each other, are obtained by reducing a compound of the formula with an alkali metal aluminium hydride or alkaline earth metal aluminium hydride in an inert solvent and then either reacting the product with a compound having an active hydrogen atom and a dilute mineral acid or with a mineral acid only to produce a compound wherein R6 represents H, and if desired treating ...

Pyrrole Aldehydes

... 1,156,477. Pyrrole aldehydes. R. FIRMENICH, G. FIRMENICH, R. E. FIRMENICH, and F. H. FIRMENICH, [trading as FIRMENICH & CIE.]. 2 May, 1966 [30 April, 1965; 18 April, 1966], No. 2378/69. Divided out of 1,156,472. Heading C2C. [Also in Division A2] The invention relates to compounds having the formulµ where R represents an amyl, alpha-methylbuty or thenyl group; and where R1 represents a butyl, amyl, alphamethylbutyl or furfuryl group. Examples describe the preparation of all the above compounds.

Derived 3 (butted-1', 3 ' - diényl) substituted cyclopropane-1-carboxylic acid, their application against the parasites of the plants and the warm-blooded animals, corresponding compositions as well as the scenting compositions containing them, their pre

New derivatives of the carboxylic acid cyclopropane their preparation, their application to the fight against the parasites of the plants, of the animals and the buildings, the compositions containing them and new intermediaries obtained.

New derivatives of pyridazin and weedkillers compositions the container.

Derived from 2-cyclohexene-1-one.

NEW ONE TETRAHYDRONAPHTHALIN AND INDANDERIVATE

VERFAHREN ZUR HERSTELLUNG VON NEUEN SUBSTITUIERTEN ALFA-AMINOOXYHYDROXAMSAUREDERIVATEN

VERFAHREN ZUR HERSTELLUNG NEUER N-(HETEROARYLMETHYL)-DESOXY-NORMORPHINE UND -NORCODEINE UND DEREN SAEUREADDITIONSSALZE

DERIVATIVES OF ALPHA PHENYLTHIOCARBONUND ALPHAPHENYLOXYCARBONSÄUREN, WHICH ARE SUITABLE FOR THE TREATMENT BY ON THE ACTIVATION OF PPAR ALPHA RESPONDING DISEASES

PROCEDURE FOR the PRODUCTION OF NEW ONE 2-CYCLOHEXEN-1-ON-DERIVATEN

PROCEDURE FOR the PRODUCTION of NEW n (HETERO ARYL METHYL) - DESOXY NORMORPHINE ONES AND - NORCODEINE AND THEIR ACID ADDITION SALTS

PRODUCTION PROCEDURE OF A UNVERSEIFBAREN AVOCADOFRAKTION WITH A HIGHER ONE FURANLIPIDENGEHALT

ALKOXYIMINOACETAMID DERIVATIVES AND YOUR USE AS MUSHROOM-KILLING MEANS

PROCEDURE FOR THE SHIFTING OF AN ALDEHYDE INTO AN ALKENE, IN PARTICULAR OF FURFURAL INTO FURFURYLIDENE.

TO MANUFACTURE PROCEDURE FOR DECARBONYLIERUNG OF FURFURAL AROUND FURAN.

NEW ONE TETRAHYDRONAPHTHALIN AND INDANDERIVATE

CYCLOPROPAN CARBOXYLSAEURE DERIVATIVES, YOUR PRODUCTION AND APPLICATION WITH THE FIGHT AGAINST PARASITS AGAINST PLANTS, ANIMALS AND RESTAURANTS, YOUR COMPOSITIONS AND INTERMEDIATE PRODUCTS.

PROCEDURE FOR the PRODUCTION of NEW n (HETERO ARYL METHYL) - DESOXY NORMORPHINE ONES AND - NORCODEINE AND THEIR ACID ADDITION SALTS

Procedure for the production of Furanen

NEW 1,3-BENZODIOXOL AND 1,2-DIALKOXYBENZOL of DERIVATIVES AS AUGEND-JERK-LOWERING MEANS

4-ARYLBUT-3-EN-2-OL DERIVATIVES

4-ARYL BUT-3-EN-2-OL DERIVATIVES

Process for the oxidation of butadiene and butene with cobalt and molybdenum oxide based catalysts

Phenylacetic acid derivatives, preparation thereof and intermediates therefor, and compositions containing them

Salvinorin derivatives and uses thereof

Vapor phase decarbonylation process

A process is provided for the synthesis of furan and related compounds by vapor phase decarbonylation of furfural and derivatives. The reaction rate, conversion, and selectivity are enhanced by adding water to the feed. The process can be run at lower temperatures than in similar processes run with essentially dry furan and related compounds.

Phenyl acetic acid derivatives, process and intermediate products for their production and agents containing them

NOVEL CYCLOPROPANECARBOXYLATES

NOVEL CYCLOPROPANECARBOXYLATES

GLUCOCORTICOID-SELECTIVE AGENTS

Compounds having Formula (I) are useful for modulating the glucocorticoid receptor in a mammal. Also disclosed are pharmaceutical compositions comprising compounds of Formula (1) and methods of treating immune, autoimmune, inflammatory, adrenal imbalance, cognitive and behavioral diseases in a mammal.

SUBSTITUTED TETRACYCLINE COMPOUNDS

The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.

INSECTICIDAL COMPOUNDS

The present invention relates to bis-amide derivatives of formula (I), to processes and intermediates for preparing them, to methods of using them to control insect, acarine, nematode and mollusc pests, and to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising them.

HETEROCYCLIC COMPOUNDS CONTAINING ETHYLENE DOUBLE BONDS AND PROCESSES FOR THEIR MANUFACTURE

CYCLOPROPANE CARBOXYLIC ACID DERIVATIVES; PROCESS FOR PREPARING THE SAME AND THEIR USE FOR CONTROLLING PLANT AND INDOOR PESTS; COMPOSITIONS THEREOF AND NEW INTERMEDIATES PRODUCED

... : L' invention concerne les composés (I') : (I') où la double liaison est E ou Z, A' est un reste d'alcool et R est un alcoyl (C1-C18) substitué par un ou plusieurs groupements fonctionnels identiques ou différents ou un aryl (C6-C14) ou un hétérocycle, éventuellement substitué par un ou plusieurs groupements fonctionnels identiques ou différents. L'invention concerne également la préparation des composés (I'), leur application à la lutte contre les parasites des végétaux et des locaux, les compositions les renfermant et les nouveaux intermédiaires obtenus.

METHOD OF LITHIATING FIVE-MEMBERED HETEROCYCLES

The invention relates to a method of lithiating CH-acidic five-membered heterocycles whereby the five-membered heterocylce is reacted with metallic lithium in an ether-containing solvent in the presence of an H acceptor.

2-(FURYLMETHYL)-6,7-BENZOMORPHANES, THE ACID ADDITION SALTS AS WELL AS PROCESSES FOR THE PRODUCTION THEREOF

NOVEL 3,4-DIARYL THIOPHENES AND ANALOGS THEREOF HAVING USE AS ANTIINFLAMMATORY AGENTS

A class of 3, 4-diary substituted thiophene, furan and pyrole derivatives and analogs thereof pharmaceutical compositions containing them and methods of using them to treat inflammation and inflammation-related disorders. Compounds of particular interes t are defined by formula (I), (see fig. I) wherein Y is selected from O. S and NR1; wherein R1 is selected from hydrido and lower alkyl; wherein X is one or two substituents selected from hydrido, halo, lower alkcoxyc arbonyl and carboxyl; wherein R2 and R3 are independently aryl or heteroaryl and wherein R2 and R3 are optionally substituted at a substitutable position with one or more radicals sel ected from sulfamyl, alkylsulfonyl, halo, lower alkcoxy and lower alkyl; or a pharmaceutically accept able slat thereof.

Verfahren zur Herstellung von Sylvan.

Verfahren zur Herstellung von cyclischen Verbindungen mit gesättigten Seitenketten.

Verfahren zur Herstellung von 2-Äthyl-furan.

Verfahren zur Umlagerung von Salzen heterocyclischer Carbonsäuren

Verfahren zur Herstellung von Furan aus Furfurol

Verfahren zur Herstellung eines Cyclopentenonderivates

Verfahren zum Oxydieren primärer und sekundärer Alkohole

Procédé pour la préparation de composés carbonylés

Procédé de préparation d'une tétrahydrobenzothiénodiazépininone

Verfahren zur Herstellung von Furanen

Verfahren zur Herstellung von heterocyclischen, Asthylendoppelbindungen enthaltenden Verbindungen

Photoleiterschicht, insbesondere für elektrophotographische Zwecke

Procédé pour la préparation d'aldéhydes non saturés

Procédé pour la préparation d'aldéhydes non saturés

Procédé pour la préparation d'(alcényl-2')-2-méthyl-3-cyclopenténones, notamment la cis-jasmone

Cns-depressant anticonvulsant tetrahydro-

CNS-depressant anticonvulsant tetrahydrobenzothienodiazepinones 6,7,8,9-Tetrahydro-5-Ar-1-R1-1H- 1 benzothieno 2,3-e 1,4 diazepin-2(3H)-ones, where Ar is Ph, o-F/Cl-Ph or 2-thienyl; R1 is H or Me are CNS-depressants & anticonvulsants.

Synthetic flavour - modifying agents for coffee and other beverages and foods

Soluble coffee material containing as flavour modifying agent a cpd. selected from substituted pyrazines, substd. pyridines, subst. furans, and subst. phenols. The agents are readily synthesized and may also be added to fruit juices tea, cocoa, etc., and to cereals, flours, confections and meats. Typical cpds. are of formula (I): (where n = 0, 1 or 2; R1 = H, alkyl; acyl or furfuryl and R2 = H or CH3, but R1 is not = R2 = CH3 if n = o).

Cns-depressant anticonvulsant tetrahydro-

CNS-depressant anticonvulsant tetrahydrobenzothienodiazepinones 6,7,8,9-Tetrahydro-5-Ar-1-R1-1H- 1 benzothieno 2,3-e 1,4 diazepin-2(3H)-ones, where Ar is Ph, o-F/Cl-Ph or 2-thienyl; R1 is H or Me are CNS-depressants & anticonvulsants.

Procédé de préparation d'esters d'acides cyclopropane-carboxyliques

Synthetic flavour - modifying agents for coffee and other beverages and foods

Soluble coffee material containing as flavour modifying agent a cpd. selected from substituted pyrazines, substd. pyridines, subst. furans, and subst. phenols. The agents are readily synthesized and may also be added to fruit juices tea, cocoa, etc., and to cereals, flours, confections and meats. Typical cpds. are of formula (I): (where n = 0, 1 or 2; R1 = H, alkyl; acyl or furfuryl and R2 = H or CH3, but R1 is not = R2 = CH3 if n = o).

PROCEDEPOUR LA PREPARATION D'UN FURANNIQUECOMPOSE.

PROCEDURE FOR THE PRODUCTION OF CYCLOPROPANVERBINDUNGEN AND THESE CONNECTIONS CONTAINING INSECTICIDES.

CHEMICAL TRANSFORMATION OF LIGNOCELLULOSIC BIOMASS INTO FUELS AND CHEMICALS

A method for converting a carbohydrate to a furan in a polar aprotic solvent in the presence of a chloride, bromide, or iodide salt or a mixture thereof and optionally in the presence of an acid catalyst, a metal halide catalyst and/or an ionic liquid (up to 40 wt %). The method can be employed in particular to produce furfural or 5-hydroxymethylfurfural. 1. A method for converting a carbohydrate to a furan which comprises the steps of:(a) preparing a mixture of the carbohydrate in a polar aprotic solvent containing a chloride, bromide, or iodide salt;(b) heating the mixture to obtain a furan.2. The method of wherein the reaction is carried out to produce greater than 30 wt % of the furan product in the reaction mixture.3. The method of wherein the concentration of the salt ranges from 0.5 wt % to 15 wt %.4. (canceled)5. (canceled)6. (canceled)7. The method of wherein the furan is HMF or furfural.8. (canceled)9. (canceled)10. (canceled)11. The method of wherein the carbohydrate is or comprises cellulose.12. The method of wherein the carbohydrate is a lignocellulosic feedstock.13. The method of wherein the solvent is DMA.14. (canceled)15. The method of further comprising adding a metal catalyst to the solvent before or after adding the carbohydrate.16. (canceled)17. (canceled)18. (canceled)19. (canceled)20. The method of wherein the ionic liquid is selected an alkylimidazolium ionic liquid claim 39 , an alkylimidazolium halide ionic liquid claim 39 , an alkylimidazolium chloride ionic liquid claim 39 , an alkylpyridinium ionic liquid claim 39 , an alkylpyridinium halide ionic liquid claim 39 , an an alkylpyridinium chloride ionic liquid or a combination thereof.21. The method of wherein the ionic liquid is selected from [EMIM]Cl claim 20 , [BMIM]Cl claim 20 , [EMIM]Br claim 20 , 1-ethyl-2 claim 20 ,3-dimethylimidazolium chloride claim 20 , 1-ethylpyridinium chloride claim 20 , 1-butyl-4-methylpyridinium chloride claim 20 , or a mixture thereof.22. (canceled)23. A ...

METHOD FOR PRODUCING FURAN COMPOUND AND FURFURAL COMPOSITION

The present invention is aimed to provide an industrially advantageous method for producing a furan compound, in which a furan compound can be efficiently obtained in a high selectivity from a furfural compound. The present invention is concerned with a method for producing a furan compound including feeding, as a raw material, a furfural composition containing a furfural compound into a reactor and subjecting to a decarbonylation reaction in the presence of a catalyst to obtain a furan compound as a product, wherein a furfural dimer concentration in the furfural composition is 1,000 ppm by weight or less, and a peroxide value in the furfural composition is 0.01 mEq/kg or more and 1.0 mEq/kg or less. 1. A method for producing a furan compound comprising feeding , as a raw material , a furfural composition containing a furfural compound into a reactor and subjecting to a decarbonylation reaction in the presence of a catalyst to obtain a furan compound as a product , wherein a furfural dimer concentration in the furfural composition is 1 ,000 ppm by weight or less , and a peroxide value in the furfural composition is 0.01 mEq/kg or more and 0.90 mEq/kg or less.2. The method for producing a furan compound according to claim 1 , wherein concentration of a compound containing nitrogen in the furfural composition as a raw material is 0.1 ppm by weight or more and 50 ppm by weight or less.3. The method for producing a furan compound according to claim 1 , wherein a concentration of the furfural compound in the furfural composition as a raw material is 99.00% by weight to 99.97% by weight.4. The method for producing a furan compound according to claim 1 , wherein a 2-acetylfuran concentration in the furfural composition as a raw material is 120 ppm by weight or more and 1 claim 1 ,000 ppm by weight or less.5. A furfural composition havinga concentration of a furfural compound of 99.00% by weight to 99.97% by weight,a concentration of a furfural dimer of 1,000 ppm by weight ...

Functionalized Bifuran and Synthesis Thereof

wherein each R1 is independently an unsubstituted or substituted 5- or 6-member 1,3-dioxo-2-yl ring radical. Processes for making the bifuran include coupling 2-(protected)-furfural. Processes for using the bifuran include deprotection, functionalization, and/or polymerization to form a polyester. The polyester can be a renewable, high-performing polyester offering a combination of low cost of production, high sustainability, and excellent performance

FRAGRANCE MIXTURE

A fragrance mixture and its applications, in particular perfume oils, cosmetic agents, application agents or washing and cleaning agents, containing a sensory effective amount of (i) (E)-2-methyl-but-2-endicarboxylic acid diethyl ester, (ii) (Z)-2-methyl-but-2-endicarboxylic acid diethyl ester or (iii) 2-methylenebutanedicarboxylic acid diethyl ester and mixtures thereof and analogous esters derived from these compounds and mixtures. 2. A fragrance mixture according to claim 1 , wherein Rand Rin the compounds of formula (i) claim 1 , formula (ii) and formula (iii) are each the same radical.3. A fragrance mixture according to claim 1 , wherein Rand Rare each independently selected from the group consisting of: linear or branched methyl claim 1 , ethyl claim 1 , propyl claim 1 , and butyl alkyl radicals.4. A fragrance mixture according to claim 1 , wherein the compounds of formula (i) claim 1 , formula (ii) and formula (iii) are each as follows:(i) (E)-2-methyl-but-2-endicarboxylic acid diethyl ester,(ii) (Z)-2-methyl-but-2-endicarboxylic acid diethyl ester, and(iii) 2-Methylenebutanedicarboxylic acid diethyl ester.5. A fragrance mixture according to claim 1 , characterized in that it contains the compound of formula (i) claim 1 , relative to the sum of the compounds of formula (i) claim 1 , formula (ii) and formula (iii) claim 1 , in an amount of 50 to 100% by weight.6. A fragrance mixture according to claim 1 , characterized in that it contains the compounds selected from the group consisting of formula (i) claim 1 , formula (ii) and formula (iii) that together amount to 0.001 to 99.999 wt. % based on the fragrance mixture.7. A fragrance mixture according to claim 1 , characterized in that it contains one or more further fragrances selected from the group consisting of:(1) Hydrocarbons;(2) Aliphatic alcohols;(3) Aliphatic aldehydes and their acetals;(4) Aliphatic ketones and their oximes;(5) Aliphatic sulphur-containing compounds;(6) Aliphatic nitriles;(7) Esters of ...

METHOD TO CONVERT MONOSACCHARIDES TO 5-(HYDROXYMETHYL) FURFURAL (HMF) USING BIOMASS-DERIVED SOLVENTS

Described is a process to produce hydroxymethyl furfural (HMF) from biomass-derived sugars. The process includes the steps of reacting a C5 and/or C6 sugar-containing reactant derived from biomass in a monophasic or biphasic reaction solution comprising water and a co-solvent. The co-solvent can be beta-, gamma-, and/or delta-lactones derived from biomass, tetrahydrofuran (THF) derived from biomass, and/or methyltetrahydrofuran (MTHF) derived from biomass. The reaction takes place in the presence of an acid catalyst and a dehydration catalyst for a time and under conditions such that at least a portion of glucose or fructose present in the reactant is converted to HMF. 1. A process to produce 5-hydroxymethylfurfural (HMF) , the process comprising:reacting a C6 sugar-containing reactant in a monophasic reaction solution comprising (i) an organic solvent selected from the group consisting of beta-, gamma-, and delta-lactones, hydrofurans, hydropyrans, and combinations thereof, and (ii) at least about 1 wt % water; in the presence of a heterogenous acid catalyst for a time and under conditions wherein at least a portion of the C6 sugar present in the reactant is converted to HMF.2. The method of claim 1 , wherein the organic solvent is miscible with water.3. The method of claim 1 , wherein the organic solvent can dissolve from 2 wt % to 25 wt % water.4. The method of claim 1 , wherein the organic solvent is a combination of two or more solvents claim 1 , wherein at least one of the solvents is miscible with water and at least one of the other solvents is not miscible with water.5. The method claim 1 , further comprising subjecting the HMF to a hydrogenolysis reaction in the presence of a suitable catalyst claim 1 , for a time and under conditions wherein at least a portion of the HMF is converted to dimethylfuran.6. The method claim 1 , further comprising oxygenating the HMF in the presence of an oxygenation catalyst claim 1 , for a time and under conditions wherein at ...

LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR TREATMENT OF CANCER, NEUROLOGICAL DISORDERS, AND FIBROTIC DISORDERS

Compounds, methods, and compositions are provided for the treatment of cancer, neurological disorders, and fibrotic disorders. Specifically, the invention includes administering an effective amount of a compound of Formula I, II, or III, or a pharmaceutically acceptable composition, salt, isotopic analog, prodrug, or combination thereof, to a subject suffering from a cancer, neurological disorder, or fibrotic disorder. 2. The method of claim 1 , wherein Ris an alkyl radical claim 1 , an alkenyl radical claim 1 , or an alkynyl radical having a carbon chain comprising C-C.3. The method of claim 1 , wherein Ris an alkyl radical claim 1 , an alkenyl radical claim 1 , or an alkynyl radical having a carbon chain comprising C-C.6. The method of claim 1 , wherein the subject is a human.17. The method of claim 16 , wherein the subject is a human. This application is a continuation of U.S. application Ser. No. 15/162,074, filed May 23, 2016, which is a continuation of U.S. application Ser. No. 14/229,130, filed Mar. 28, 2014, which claims the benefit of U.S. Provisional Application No. 61/853,163, filed Mar. 29, 2013, the contents of which are incorporated by reference in their entireties.The present invention is directed to compounds, methods, and compositions for the treatment of cancer, neurological disorders, and fibrotic disorders.Every year, cancer claims the lives of more than half a million Americans. Cancer is the second leading cause of death in the United States, exceeded only by heart disease. One of every four deaths in the United States is cancer-related.Cancers arise from cells that have undergone genetic alterations, leading to abnormal proliferation on a clonal basis. These genetic alterations can include activation of oncogenes or inactivation of tumor suppressors. Different types of cancers have been found to have a wide range of underlying genetic alterations and vary in their pathological progression to the cancerous state, including in their ability to ...

METHOD FOR PRODUCING FURFURAL, AND METHOD FOR PRODUCING FURAN

A problem is to provide an industrially advantageous method in which in purifying a furfural composition, the formation of a solid matter which have been unable to be controlled so far is stably reduced, and furfural is purified with high efficiency wherein the problem has been solved by a method for producing furfural including distilling a composition containing furfural by a distillation column to obtain furfural, wherein a concentration of a furfural dimer in a column bottom liquid of the distillation column is controlled to 20 ppm by mass to 5,000 ppm by mass. 1. A method for producing furfural comprising distilling a composition comprising furfural by a distillation column to obtain furfural , wherein a concentration of a furfural dimer in a column bottom liquid of the distillation column is 20 ppm by mass to 5 ,000 ppm by mass.2. The method for producing furfural according to claim 1 , wherein a concentration of furancarboxylic acid in the column bottom liquid of the distillation column is 50 ppm by mass to 8 claim 1 ,000 ppm by mass.3. The method for producing furfural according to claim 1 , including a step of prior to distilling the composition comprising furfural by the distillation column claim 1 , concentrating a compound having a higher boiling point than furfural in crude furfural obtained after bringing the crude furfural into contact with an anion exchange resin and/or a basic compound in advance claim 1 , to obtain the composition comprising furfural.4. The method for producing furfural according to claim 1 , wherein a concentration of furfural in the composition comprising furfural is 87.0% by mass or more and 99.0% by mass or less.5. The method for producing furfural according to claim 1 , wherein a temperature of the column bottom liquid of the distillation column for distilling the composition comprising furfural is 60 to 180° C.6. The method for producing furfural according to claim 1 , wherein an acid value of the column bottom liquid of the ...

Oligomeric (TH)FP, production and uses therefor

A method for the isolation of oligomeric 2, 2-difurylpropane (DTHFP) suitable for use on an industrial scale. A method can include using oligomeric 2, 2-difurylpropane, in particular, its use can be as a polar modifier for butadiene and styrene butadiene polymerisation so is to produce rubber. Utilising the material as an alternative to DTHFP in rubber production avoids subsequent leaching of the DTHFP into the environment as the oligomeric 2, 2-difurylpropane (DTHFP) gives rise to much lower levels of leaching.

METHODS OF PRODUCING ALKYLFURANS

Provided herein are methods of producing dialkylfurans, such as 2,5-dimethylfuran, and other alkyl furans, such as 2-methylfuran. For example, 2,5-dimethylfuran may be produced by reducing (5-methylfuran-2-yl)methanol or 2-(chloromethyl)-5-methylfuran. 2. The method of claim 1 , wherein the basic solid support comprises a basic metal oxide.3. The method of claim 1 , wherein the basic solid support comprises a solid support modified by an alkali metal or an alkali earth metal.4. The method of claim 1 , wherein the basic solid support comprises a solid support modified by a base.5. The method of claim 1 , wherein the basic solid support comprises BeO claim 1 , MgO claim 1 , CaO claim 1 , SrO claim 1 , BaO claim 1 , ZnO claim 1 , AlO claim 1 , YO claim 1 , LaO claim 1 , CeO claim 1 , ThO claim 1 , TiO claim 1 , ZrOor SnO claim 1 , or any combinations thereof.739-. (canceled)4143-. (canceled) This application claims priority to U.S. Provisional Patent Application No. 62/037,806, filed Aug. 15, 2014, which is incorporated herein by reference in its entirety.The present disclosure relates generally to methods of producing dialkylfurans and other alkylfurans, and more specifically to methods of producing 2,5-dimethylfuran and 2-methylfuran.Dialkylfurans, such as 2,5-dimethylfuran (DMF), and other alkylfurans have potential applications for use as biofuels. Several methods are known in the art to produce 2,5-dimethylfuran. Current methods known in the art to produce 2,5-dimethylfuran from other furan compounds have been challenging with respect to minimizing the furan ring reduction. Thus, what is needed in the art are methods of selectively reducing furan compounds to produce 2,5-dimethylfuran and other alkylfurans.Provided herein are methods to reduce furan compounds to produce alkylfurans. In some aspects, provided is a method of producing a compound of formula (I′):wherein:wherein:In some embodiments, the compound of formula (A) is reduced to produce the compound of ...

PROCESSES FOR THE PREPARATION OF ALKYL FURANS USING BIFUNCTIONAL COPPER CATALYSTS

The present disclosure relates to the selective hydrodeoxygenation (HDO) of bio-based furanic ketones with a bifunctional copper-based catalyst in the presence of a solvent to prepare alkyl furans with high yield, purity, and scalability. The alkyl furans prepared herein are useful in the preparation of surfactants. 2. The method of claim 1 , wherein said bifunctional copper-based catalyst is a heterogeneous catalyst selected from the group consisting of 10% Cu/SiO claim 1 , 10% Cu/PERLKAT 46-10 claim 1 , 10% Cu/PERLKAT 79-3 claim 1 , 10% Cu/HZSM5 claim 1 , and 10% Cu/zeolite Y.3. The method of claim 2 , wherein said bifunctional copper-based catalyst is a heterogeneous catalyst selected from the group consisting of 10% Cu/zeolite Y claim 2 , 10% Cu/HZSM-5 claim 2 , and 10% Cu/PERLKAT 79-3.4. The method of claim 1 , wherein the compound of Formula II is present in an amount of about 5 to about 10 moles relative to 1 mole of the bifunctional copper-based catalyst.5. The method of claim 1 , wherein said solvent is selected from the group consisting of hexane claim 1 , cyclohexane claim 1 , dimethylformamide (DMF) claim 1 , dimethyl sulfoxide (DMSO) claim 1 , dichloromethane claim 1 , pentane claim 1 , tetrahydrofuran (THF) claim 1 , and acetone.6. The method of claim 5 , wherein the solvent is hexane.7. The method of claim 1 , wherein the method is performed at a temperature in the range of about 160° C. to about 240° C.8. The method of claim 7 , wherein the method is performed at a temperature of about 220° C.9. The method of claim 1 , wherein said alkyl is linear or branched Calkyl.11. The method of claim 9 , wherein said alkyl is linear Calkyl.12. The method of claim 1 , wherein the method achieves at least 75% selective hydrodeoxygenation of the ketone moiety.13. The method of claim 1 , wherein the method achieves at least 95% selective hydrodeoxygenation of the ketone moiety.14. The method of claim 1 , wherein the method achieves at least 98% selective ...

HYDROPHOBIC PALLADIUM/METAL ORGANIC FRAMEWORK MATERIAL, PREPARATION METHOD THEREOF, AND APPLICATION THEREFOR FOR USE IN SYNTHESIZING 2,5-DIMETHYLFURAN

A hydrophobic palladium/metal organic framework (MOF) material, which is a solid catalyst material obtained by taking a porous MOF as a carrier, introducing elementary palladium by means of an immersion-reduction method, and performing polydimethylsiloxane coating layer processing. A method which uses hydrophobic palladium/MOF material to selectively catalyze hexoses to prepare 2,5-dimethylfuran comprises: dissolving a hexose into an alcohol; using the hydrophobic palladium/MOF material as a catalyst and polymethylhydrosiloxane as a hydrogen donor, reacting at 70 to 130° C. for 0.25 to 12 h under the action of an acidic additive; the concentration of the hexose in the alcohol is 0.2 to 10 wt %, and the total amount of Pd contained in the hydrophobic palladium/MOF material relative to a hexose is 0.1 to 5 mol %. The hydrophobic palladium/MOF material has a stable structure, and under the same conditions, has a catalyzing efficiency which is significantly higher than that of commercially available palladium on carbon and common palladium/MOF materials. 1. A hydrophobic palladium/metal organic framework (MOF) material , which is obtained by immersing an MOF serving as a carrier to obtain a palladium/MOF material , reducing the palladium/MOF material in a hydrogen atmosphere at 200 to 300° C. for 2 to 5 h , and finally performing polydimethylsiloxane coating layer processing.2. The hydrophobic palladium/MOF material according to claim 1 , wherein the MOF is obtained by dissolving a transition metal salt and an equivalent mole number of terephthalic acid in deionized water or N claim 1 ,N-dimethylformamide claim 1 , performing hydrothermal treatment at 120 to 220° C. for 12 to 72 h claim 1 , and then performing filtering claim 1 , washing and vacuum drying; wherein the transition metal salt is chloride salt or nitrate of Cu claim 1 , Al claim 1 , Cr claim 1 , Fe or Zr.3. The hydrophobic palladium/MOF material according to claim 1 , wherein immersing the MOF comprises ...

PROCESSES FOR SELECTIVE EXTRACTION OF UNSAPONIFIABLE MATERIALS FROM RENEWABLE RAW MATERIALS BY REACTIVE TRITURATION IN THE PRESENCE OF A COSOLVENT

A method for extracting an unsaponifiable fraction from a renewable raw material, includes the reactive trituration of the raw material dehydrated in the presence of at least one polar organic solvent including at least one light alcohol, at least one non-polar cosolvent immiscible with the light alcohol and at least one catalyst, resulting in the formation of a polar organic phase enriched with lipids functionalized with one or more function(s) chosen from hydroxyl, epoxide, ketone, thiol, aldehyde, ether and amine functions, and of a non-polar organic phase enriched with lipids containing no or few hydroxyl, epoxide, ketone, thiol, aldehyde, ether and amine function(s), and thereafter the concentration of the organic phases. 111-. (canceled)12. A method for extracting an unsaponifiable fraction from a renewable raw material comprising lipids functionalized with one or more function(s) chosen from hydroxyl , epoxide , ketone , thiol , aldehyde , ether and amine functions , comprising the following steps:a) dehydration optionally preceded or followed with a conditioning of the renewable raw material,b) reactive trituration of the raw material dehydrated and optionally conditioned, in the presence of at least one polar organic solvent comprising at least one light alcohol, at least one non-polar cosolvent immiscible with said light alcohol and at least one catalyst, resulting in the formation of a polar organic phase enriched with lipids functionalized with one or more function(s) chosen from hydroxyl, epoxide, ketone, thiol, aldehyde, ether and amine functions,c) concentration of the polar organic phase to obtain a mixture enriched with an unsaponifiable fraction, optionally preceded, accompanied or followed with a heat treatment at a temperature higher than or equal to 75° C., preferably higher than or equal to 80° C.,and comprising optionally the following steps:d) saponification of the mixture enriched with the unsaponifiable fraction,e) extraction of the ...

LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR TREATMENT OF CANCER, NEUROLOGICAL DISORDERS, AND FIBROTIC DISORDERS

Compounds, methods, and compositions are provided for the treatment of cancer, neurological disorders, and fibrotic disorders. Specifically, the invention includes administering an effective amount of a compound of Formula I, II, or III, or a pharmaceutically acceptable composition, salt, isotopic analog, prodrug, or combination thereof, to a subject suffering from a cancer, neurological disorder, or fibrotic disorder. 2. The method of claim 1 , wherein the compound is suitable for topical administration.4. The method of claim 3 , wherein the compound is suitable for topical administration.6. The method of claim 5 , wherein the compound is suitable for topical administration. This application is a continuation of U.S. patent application Ser. No. 16/721,638, filed Dec. 19, 2019, which is a continuation of U.S. patent application No. Ser. No. 16/110,778, filed Aug. 23, 2018, which is a continuation of U.S. patent application Ser. No. 15/782,535, filed Oct. 12, 2017, which is a continuation of U.S. patent application Ser. No. 15/162,074, filed May 23, 2016, which is a continuation of U.S. patent application Ser. No. 14/229,130, filed Mar. 28, 2014, which claims the benefit of U.S. Provisional Application No. 61/853,163, filed Mar. 29, 2013, the contents of which are incorporated by reference in their entireties.The present invention is directed to compounds, methods, and compositions for the treatment of cancer, neurological disorders, and fibrotic disorders.Every year, cancer claims the lives of more than half a million Americans. Cancer is the second leading cause of death in the United States, exceeded only by heart disease. One of every four deaths in the United States is cancer-related.Cancers arise from cells that have undergone genetic alterations, leading to abnormal proliferation on a clonal basis. These genetic alterations can include activation of oncogenes or inactivation of tumor suppressors. Different types of cancers have been found to have a wide range ...

FURAN MONOMER HAVING BIFUNCTIONAL HYDROXYMETHYL GROUP AND PREPARATION METHOD THEREFOR

The present disclosure relates to a method of preparing a furan monomer having a bifunctional hydroxymethyl group (2, 5-bis(hydroxymethyl) furan (BHMF)). The method includes converting furfuryl alcohol to a low-molecular weight furan mixture extracting and purifying the furan monomer having a bifunctional hydroxymethyl group from the low-molecular weight furan mixture. 1. A method of preparing a furan monomer having a bifunctional hydroxymethyl group (2 , 5-bis(hydroxymethyl) furan (BHMF)) , the method comprising:converting furfuryl alcohol to a low-molecular weight furan mixture; andextracting and purifying the furan monomer having a bifunctional hydroxymethyl group from the low-molecular weight furan mixture.2. The method of claim 1 , wherein converting comprises hydroxymethylating the furfuryl alcohol by mixing the furfuryl alcohol claim 1 , solid-phase formaldehyde claim 1 , and an acid catalyst.3. The method of claim 2 , wherein the solid-phase formaldehyde comprises paraformaldehyde.4. The method of claim 3 , wherein the hydroxymethylating allows the furfuryl alcohol to be associated with monomeric formaldehyde produced by thermal degradation of the paraformaldehyde.5. The method of claim 2 , wherein the hydroxymethylating is conducted at a temperature of 100° C. to 150° C.6. The method of claim 2 , wherein the furfuryl alcohol is mixed at a 2- to 30-fold greater molar ratio to the formaldehyde.7. The method of claim 2 , wherein the acid catalyst is mixed in an amount of 0.05 phr to 0.3 phr relative to the furfuryl alcohol.8. The method of claim 2 , wherein the acid catalyst is an organic acid with a pKa of 3.0 to 6.4 and is selected from the group consisting of acetic acid claim 2 , acetoacetic acid claim 2 , adipic acid claim 2 , azelaic acid claim 2 , benzoic acid claim 2 , citric acid claim 2 , cyclohexanecarboxylic acid claim 2 , enolpyruvic acid claim 2 , formic acid claim 2 , fumaric acid claim 2 , galactaric acid claim 2 , galactonic acid claim 2 , ...

PROCESSES FOR SELECTIVE EXTRACTION OF UNSAPONIFIABLE MATERIALS FROM RENEWABLE RAW MATERIALS BY LIQUID-LIQUID EXTRACTION IN THE PRESENCE OF A COSOLVENT

A method for extracting an unsaponifiable fraction from a solid renewable raw material, includes the extraction of the fats from the solid renewable raw material, leading to the production of an oil, the concentration of the oil so as to obtain a mixture enriched in unsaponifiable fraction, and the liquid-liquid extraction of the mixture enriched in unsaponifiable fraction, in the presence of at least one polar organic solvent and at least one non-polar cosolvent immiscible with the polar organic solvent, resulting in the formation of an organic polar phase enriched in lipids functionalized with one or more function(s) chosen from hydroxyl, epoxide, ketone, thiol, aldehyde, ether and amine functions, and to the formation of a non-polar organic phase enriched in lipids containing no or few hydroxyl, epoxide, ketone, thiol, aldehyde, ether and amine function(s), then the concentration of the organic phases. 111-. (canceled)12. A method for extracting an unsaponifiable fraction from a solid renewable raw material comprising fats , and in particular lipids functionalized with one or more function(s) chosen from hydroxyl , epoxide , ketone , thiol , aldehyde , ether and amine functions , comprising the following steps:a) optional dehydration possibly preceded or followed with a conditioning of the renewable raw material,b) extraction of the fats from the raw material optionally dehydrated and optionally conditioned to obtain an oil,c) concentration of the oil resulting from step b) so as to obtain a mixture enriched in unsaponifiable fraction,d) liquid-liquid extraction of the mixture enriched in unsaponifiable fraction in the presence of at least one polar organic solvent and at least one non-polar cosolvent immiscible with said polar organic solvent, leading to the formation of an organic polar phase enriched in lipids functionalized with one or more function(s) chosen from hydroxyl, epoxide, ketone, thiol, aldehyde, ether and amine functions,and optionally comprising ...

CRYSTALLINE MICROPOROUS MATERIAL MEDIATED CONVERSION OF C1-3 OXYGENATE COMPOUNDS TO C4 OXYGENATE COMPOUNDS

A process for the preparation of Coxygenate compounds such as threose, erythrose or erythrulose starting from a composition comprising Coxygenate compounds such as formaldehyde, glycolaldehyde, glyoxal, pyruvaldehyde or acetol, wherein the process is carried out in the presence of a crystalline microporous material having a ring pore structure selected from an eight-membered ring pore structure or a ten-membered ring pore structure. 1. A process for the preparation of one or more Coxygenate compounds from a composition comprising Coxygenate compounds , wherein the process is carried out in the presence of a crystalline microporous material comprising a ring pore structure selected from one or more of the group consisting of an eight-membered ring pore structure and a ten-membered ring pore structure.2. A process according to claim 1 , wherein the Coxygenate compounds are compounds selected from one or more of the group consisting of threose claim 1 , erythrose and erythrulose.3. A process according to claim 1 , wherein the composition comprising Coxygenate compounds comprises one or more compounds selected from the group consisting of formaldehyde claim 1 , glycolaldehyde claim 1 , glyoxal claim 1 , pyruvaldehyde and acetol.4. A process according to claim 1 , wherein the composition comprising Coxygenate compounds is obtainable from the pyrolysis of biomass or one or more oxygenate compounds selected from the group consisting of fructose claim 1 , glucose claim 1 , sucrose claim 1 , xylose or isomers thereof.5. A process according to claim 1 , wherein the composition comprising Coxygenate comprises a solvent selected from one or more of the groups consisting of water claim 1 , alcohol and a water and alcohol mixture.6. A process according to claim 1 , wherein the alcohol is selected from one or more of the group consisting of methanol and ethanol.7. A process according to claim 1 , wherein the crystalline microporous material comprising a small or medium pore ...

PROCESS FOR THE PRODUCTION OF FURAN AND ITS DERIVATIVES

The present invention provides a process for the production of furan, said process comprising the steps of: i) contacting furfural with a decarbonylation catalyst in a decarbonylation reactor to produce a gaseous decarbonylation reaction product stream comprising furan and carbon monoxide; ii) contacting said gaseous decarbonylation reaction product stream with a solvent stream comprising furfural; iii) absorbing at least a portion of the furan present in the gaseous decarbonylation reaction product stream into the solvent stream to provide a furan-containing solvent stream and a gaseous stream comprising carbon monoxide; iv) separating the furan from the furan containing solvent stream by distillation to provide a first furan stream; and v) using at least a portion of the remaining solvent stream comprising furfural as at least a portion of the furfural provided to the decarbonylation reactor. 1. A process for the production of furan , said process comprising the steps of:i) contacting furfural with a decarbonylation catalyst in a decarbonylation reactor to produce a gaseous decarbonylation reaction product stream comprising furan and carbon monoxide;ii) contacting said gaseous decarbonylation reaction product stream with a solvent stream comprising furfural;iii) absorbing at least a portion of the furan present in the gaseous decarbonylation reaction product stream into the solvent stream to provide a furan-containing solvent stream and a gaseous stream comprising carbon monoxide;iv) separating the furan from the furan containing solvent stream by distillation to provide a first furan stream; andv) using at least a portion of the remaining solvent stream comprising furfural as at least a portion of the furfural provided to the decarbonylation reactor.2. A process according to claim 1 , wherein thedecarbonylation reaction stream is subjected to cooling and/or compression before being contacted with a solvent stream in step ii) and any liquid condensed is separated. ...

PROCESS FOR THE PRODUCTION OF FURAN AND ITS DERIVATIVES

The present invention provides a process for the treatment of a liquid first furan stream comprising furan and carbon monoxide, said process comprising the steps of: i) contacting said first furan stream with a CO-lean first gaseous stream; and ii) stripping at least a portion of the carbon monoxide in the first furan stream into the first gaseous stream to produce a second furan stream comprising less carbon monoxide than the first furan stream and a CO-enriched second gaseous stream. 1. A process for the treatment of a liquid first furan stream comprising furan and carbon monoxide , said process comprising the steps of:i) contacting said first furan stream with a CO-lean first gaseous stream; andii) stripping at least a portion of the carbon monoxide in the first furan stream into the first gaseous stream to produce a liquid second furan stream comprising less carbon monoxide than the first furan stream and a CO-enriched second gaseous stream.2. A process according to claim 1 , wherein the CO-lean first gaseous stream comprises one or more gases from the group consisting of hydrogen claim 1 , nitrogen claim 1 , carbon dioxide claim 1 , steam and methane.3. A process according to claim 2 , wherein the CO-lean first gaseous stream comprises hydrogen.4. A process according to claim 1 , wherein the CO-lean first gaseous stream comprises no more than 10 vol % CO.5. A process according to claim 1 , wherein the process further comprises the steps of:i) contacting the second furan stream with hydrogen in the presence of a hydrogenation catalyst to produce a hydrogenation reaction product stream comprising THF, NBA and/or 1,4-BDO and hydrogen;ii) separating the hydrogenation reaction product stream into a stream comprising THF, NBA and/or 1,4-BDO and a third gaseous stream comprising hydrogen; andiii) using at least a portion of said third gaseous stream comprising hydrogen as the first CO-lean gaseous stream.6. A process according to claim 1 , wherein the hydrogenation ...

METHOD FOR PREPARING 2,5-DIMETHYLFURAN BY DIRECTLY CATALYZING CARBOHYDRATE USING MODIFIED PD/C

A preparation method of an acidic and hydrophobic Pd/C catalytic material comprises performing a simple treatment with chlorosulfonic acid and trimethylchlorosilane, washing and drying a treatment product to obtain a modified Pd/C catalytic material. A method for preparing 2,5-methylfuran by catalyzing a carbohydrate with modified Pd/C comprises: dissolving the carbohydrate in alcohol, allowing a reaction to proceed with modified Pd/C as a catalyst and polymethylhydrosiloxane as a hydrogen donor at a temperature of 80˜140° C. for 1-5 hours, and performing centrifugation to separate the catalyst from the product. The content of the modified Pd/C content is 1-3 mol % relative to the carbohydrate; the polymethylhydrosiloxane amount is equivalent to 4-10 times the carbohydrate amount, and the carbohydrate concentration in the alcohol is 2-6 wt %. The method overcomes the defect of being difficult to prepare the 2,5-methylfuran by directly catalyzing the carbohydrate, and features moderate reaction conditions and high activity. 16-. (canceled)7. A method of preparing 2 ,5-methylfuran by directly catalyzing carbohydrates with modified Pd/C , comprising:heating a mixture solution comprising the carbohydrates, the modified Pd/C as a catalyst, and a hydrogen donor to obtain the 2,5-methylfuran;wherein the modified Pd/C is obtained by treating Pd/C with chlorosulfonic acid to obtain an acidic Pd/C catalytic material, and then reacting the acidic Pd/C catalytic material with trimethylchlorosilane.8. The method of preparing 2 claim 7 ,5-methylfuran by directly catalyzing carbohydrates with modified Pd/C according to claim 7 , wherein the modified Pd/C comprises a Pd content within a range of 0.5˜15 wt %.9. The method of preparing 2 claim 7 ,5-methylfuran by directly catalyzing carbohydrates with modified Pd/C according to claim 7 , wherein the hydrogen donor is polymethylhydrosiloxane.10. The method of preparing 2 claim 9 ,5-methylfuran by directly catalyzing carbohydrates with ...

Cerium-containing zeolites and coke reduction methods

The invention provides a catalyst system for catalytic fast pyrolysis comprising a cerium-incorporated HZSM-5 zeolite (Catalyst 1), and methods of making and using the same. The invention also provides a process for reducing coke formation during catalytic fast pyrolysis of biomass using HZSM-5, wherein the process can include incorporating cerium into the HZSM-5 zeolite to produce Catalyst 1 prior to the catalytic fast pyrolysis.

METHODS OF PRODUCING ALKYLFURANS

Provided herein are methods of producing dialkylfurans, such as 2,5-dimethylfuran, and other alkyl furans, such as 2-methylfuran. For example, 2,5-dimethylfuran may be produced by reducing (5-methylfuran-2-yl)methanol or 2-(chloromethyl)-5-methylfuran. 5. The method of claim 1 , wherein Ris Calkyl.6. The method of claim 1 , wherein Ris —(CH)Y.7. The method of claim 1 , wherein Ris —(CH)CH(O).8. The method of claim 1 , wherein Ris —(CH)OH.9. The method of claim 1 , wherein Ris —(CH)X.18. The method of claim 1 , wherein Y is chloro.19. The method of claim 1 , wherein X is chloro.21. The method of claim 1 , wherein the compound of formula (A) is converted to the compound of formula (I′) in the further presence of acid.22. The method of claim 1 , wherein the compound of formula (A) is converted to the compound of formula (I′) in the further presence of solvent.23. The method of claim 22 , wherein the solvent comprises organic solvent.24. The method of claim 22 , wherein the solvent comprises aromatic solvent.25. The method of claim 22 , wherein the solvent comprises at least one mono-aryl compound claim 22 , at least one di-aryl compound claim 22 , or at least one tri-aryl compound claim 22 , or any mixtures thereof.26. The method of claim 25 , wherein the at least one mono-aryl compound is toluene or para-xylene.27. (canceled)28. A method of producing 2 claim 25 ,5-dimethylfuran claim 25 , comprising:a) providing (5-methylfuran-2-yl)methanol;b) converting the (5-methylfuran-2-yl)methanol to 2-(chloromethyl)-5-methylfuran in the presence of an acid; andc) reducing the 2-(chloromethyl)-5-methylfuran to produce 2,5-dimethylfuran.29. The method of claim 27 , wherein the (5-methylfuran-2-yl)methanol is provided by:i) providing 5-methylfuran-2-carbaldehyde; andii) converting the 5-methylfuran-2-carbaldehyde to (5-methylfuran-2-yl)methanol in the presence of acid, hydrogen and a catalyst.30. The method of any one of claim 27 , wherein the (5-methylfuran-2-yl)methanol is ...

SYNTHESIS OF ALKYLFURANS

The invention provides a method for preparing a 2,5-dialkyl furan. The method includes forming a reaction mixture containing a catalyst, a hydrogen source, and 2-haloalkylfuran starting material under conditions sufficient to form the 2,5-dialkyl furan. The 2-haloalkylfuran starting material can be derived from biomass, and the 2,5-dialkyl furan product can be used as a biofuel or as a chemical feedstock. 5. The method of claim 4 , wherein the carbonyl derivatizing agent is selected from the group consisting of an orthoester claim 4 , a Calkanol claim 4 , a Calkane-diol claim 4 , an acid chloride claim 4 , and an acid anhydride.6. The method of claim 4 , wherein the acid is selected from the group consisting of an acidic ion exchange resin claim 4 , a sulfonic acid claim 4 , sulfamic acid claim 4 , and hydrochloric acid.7. The method of claim 1 , wherein Rhas the formula —(CHX)R claim 1 , wherein X is halogen and Ris Calkyl.8. The method of claim 1 , wherein Ris chloromethyl.9. The method of claim 2 , wherein the compound of formula IIa is 5-(chloromethyl)furfural.10. The method of claim 1 , wherein the compound of formula I is 2 claim 1 ,5-dimethylfuran.11. The method of claim 1 , wherein the hydrogen source is hydrogen gas.12. The method of claim 1 , wherein the catalyst is a transition metal-based catalyst.13. The method of claim 12 , wherein the catalyst is palladium on carbon.18. The method of claim 1 , wherein the reaction mixture comprising the catalyst claim 1 , the hydrogen source claim 1 , and the compound of formula II further comprises N claim 1 ,N-dimethylformamide.19. The method of any of claim 18 , wherein the reaction mixture comprising the catalyst claim 18 , the hydrogen source claim 18 , the compound of formula II claim 18 , and N claim 18 ,N-dimethylformamide further comprises acetic acid.20. The method of claim 1 , wherein the reaction mixture comprising the catalyst claim 1 , the hydrogen source claim 1 , and the compound of formula II further ...

Lipidic Furan, Pyrrole, and Thiophene Compounds for Treatment of Cancer, Neurological Disorders, and Fibrotic Disorders

Compounds, methods, and compositions are provided for the treatment of cancer, neurological disorders, and fibrotic disorders. Specifically, the invention includes administering an effective amount of a compound of Formula I, II, or III, or a pharmaceutically acceptable composition, salt, isotopic analog, prodrug, or combination thereof, to a subject suffering from a cancer, neurological disorder, or fibrotic disorder. 2. The method of claim 1 , wherein R claim 1 , R claim 1 , Ror Ris an alkyl radical claim 1 , an alkenyl radical claim 1 , or an alkynyl radical having a carbon chain comprising C-C.3. The method of claim 1 , wherein R claim 1 , R claim 1 , Ror Ris an alkyl radical claim 1 , an alkenyl radical claim 1 , or an alkynyl radical having a carbon chain comprising C-C.4. The method of claim 1 , wherein Ror R claim 1 , is an alkyl radical claim 1 , an alkenyl radical claim 1 , or an alkynyl radical having a carbon chain comprising C-C.5. The method of claim 1 , wherein Ror R claim 1 , is an alkyl radical claim 1 , an alkenyl radical claim 1 , or an alkynyl radical having a carbon chain comprising C-C.9. The method of claim 1 , wherein the cancer is a solid tumor.10. The method of claim 9 , wherein the solid tumor is a breast cancer.11. The method of claim 10 , wherein the breast cancer is an invasive breast cancer.12. The method of claim 9 , wherein the solid tumor is a lung cancer.13. The method of claim 9 , wherein the solid tumor is a colon cancer.14. The method of claim 1 , wherein the host is a human.15. The method of claim 1 , wherein the compound is administered in combination with a second therapeutic agent claim 1 , wherein the second therapeutic agent is a chemotherapeutic agent.16. The method of claim 8 , wherein the cancer is a breast cancer.18. The method of claim 17 , wherein R claim 17 , R claim 17 , Ror Ris an alkyl radical claim 17 , an alkenyl radical claim 17 , or an alkynyl radical having a carbon chain comprising C-C.19. The method of ...

Low Temperature and Efficient Fractionation of Lignocellulosic Biomass Using Recyclable Organic Solid Acids

Methods of fractionating lignocellulosic biomass using hydrotropic solid organic acids are provided. Also provided are methods of forming lignin particles, furans, sugars, and/or lignocellulosic micro- and nanofibrils from the liquid and solid fractions produced by fractionation process. The fractionation can be carried out at low temperatures with short reaction times. 1. A method for treating lignocellulosic biomass , the method comprising:dispersing a lignocellulosic biomass in an aqueous solution comprising a hydrotropic solid organic acid, wherein the concentration of the hydrotropic solid organic acid in the solution is higher than its minimal hydrotrope concentration;maintaining the solution at a temperature and for a time sufficient to dissolve at least 10 wt. % of the lignin in the lignocellulosic biomass; andseparating the solution and the dispersed lignocellulosic biomass into a spent acid solution comprising dissolved lignin and a water-insoluble cellulose-rich solids fraction comprising water-insoluble lignocellulosic solid residues.2. The method of claim 1 , wherein the temperature is no greater than 100° C. and the time is no greater than 300 minutes.3. The method of claim 1 , wherein the lignocellulosic biomass comprises wood chips claim 1 , milled wood claim 1 , commercial technical lignin claim 1 , or a combination thereof.4. The method of claim 1 , wherein the lignocellulosic biomass is a hardwood and at least 10 wt. % of the lignin in the hardwood is dissolved.5. The method of claim 1 , wherein the lignocellulosic biomass is softwood and at least 10 wt. % of the lignin in the softwood is dissolved.6. The method of claim 1 , wherein the lignocellulosic biomass is commercial technical lignin and the amount of the technical lignin dissolved is at least 2 g/100 g solution.7. The method of claim 1 , further comprising fibrillating the lignocellulosic biomass prior to dispersing the lignocellulosic biomass in the aqueous solution comprising the ...

LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR TREATMENT OF CANCER, NEUROLOGICAL DISORDERS, AND FIBROTIC DISORDERS

Compounds, methods, and compositions are provided for the treatment of cancer, neurological disorders, and fibrotic disorders. Specifically, the invention includes administering an effective amount of a compound of Formula I, II, or III, or a pharmaceutically acceptable composition, salt, isotopic analog, prodrug, or combination thereof, to a subject suffering from a cancer, neurological disorder, or fibrotic disorder. 110.-. (canceled) This application is a continuation of U.S. application Ser. No. 16,110,778, filed Aug. 23, 2018, which is a continuation of U.S. application Ser. No. 15/782,535, filed Oct. 12, 2017, which is a continuation of U.S. application Ser. No. 15/162,074, filed May 23, 2016, which is a continuation of U.S. application Ser. No. 14/229,130, filed Mar. 28, 2014, which claims the benefit of U.S. Provisional Application No. 61/853,163, filed Mar. 29, 2013, the contents of which are incorporated by reference in their entireties.The present invention is directed to compounds, methods, and compositions for the treatment of cancer, neurological disorders, and fibrotic disorders.Every year, cancer claims the lives of more than half a million Americans. Cancer is the second leading cause of death in the United States, exceeded only by heart disease. One of every four deaths in the United States is cancer-related.Cancers arise from cells that have undergone genetic alterations, leading to abnormal proliferation on a clonal basis. These genetic alterations can include activation of oncogenes or inactivation of tumor suppressors. Different types of cancers have been found to have a wide range of underlying genetic alterations and vary in their pathological progression to the cancerous state, including in their ability to invade surrounding normal tissues and metastasize.Conventional approaches to cancer treatment include surgery, radiation, and chemotherapy, or a combination thereof. However, for more aggressive and invasive cancers, these treatments have ...

SYNTHESIS OF OLEOFURANS

Disclosed herein is a method for making oleofuran compounds according to formula 3

METHODS OF PRODUCING ALKYLFURANS

Provided herein are methods of producing dialkylfurans, such as 2,5-dimethylfuran, and other alkyl furans, such as 2-methylfuran. For example, 2,5-dimethylfuran may be produced by hydrogenation of (5-methylfuran-2-yl) methanol or 2-(chloromethyl)-5-methylfuran in the presence of a solid supported metal catalyst having an excess of either basic or acidic sites (as determined by chemisorption of CO2 or NH3). The process could further include a urea reagent (TMU, DMPU, TMI) and an alkyl benzene.

PROCESS FOR PRODUCING FURAN AND ITS DERIVATIVES

An efficient, hydrogen gas-free, high yielding, moderate temperature and safe-to-handle process for producing furan and its derivatives from furfural, which comprises contacting furfural and water-isopropanol mixture with a supported Pd or Pt catalyst at a temperature in the range of 200-250° C., is reported. 2. The process as claimed in claim 1 , wherein the ratio by weight of furfural to the water-isopropanol is in the range 1:5 to 1:25.3. The process as claimed in claim 1 , wherein weight ratio of catalyst to furfural ranges between 2 and 5 wt %.4. The process as claimed in claim 1 , wherein the supported metal catalyst is a supported Pd or Pt catalyst and the Pd or Pt catalyst content on the support ranges from 2-10 wt %.5. The process as claimed in claim 4 , wherein the supported metal catalyst is selected from the group consisting of alumina claim 4 , ceria claim 4 , zirconia claim 4 , ceria-zirconia claim 4 , sulphated zirconia claim 4 , silica claim 4 , carbon claim 4 , clay claim 4 , hydrotalcite claim 4 , MgO-AlOand mixtures thereof.6. The process as claimed in claim 1 , wherein the reaction is carried out in a semi-batch claim 1 , continuous stirred tank or a fixed-bed reactor.7. The process as claimed in claim 1 , wherein the inert gas is nitrogen gas claim 1 , argon gas claim 1 , helium gas or a mixture of two or more of such gases.8. The process as claimed in claim 1 , wherein the water-iso-propanol ratio by weight in the mixture is between 1:1 and 1:5.9. The process as claimed in claim 1 , wherein the catalyst is a recyclable catalyst.10. The process as claimed in claim 1 , wherein the wt % furfural converted to the compound is in the range of 29-99.7 wt %.11. The process as claimed in claim 1 , wherein the yield of the compound of formula 1 is in the range of 68-90 wt %. The following specification particularly describes the invention and the manner in which it is to be performed.The present invention relates to an improved, efficient hydrogen gas- ...

METHOD FOR PREPARING FURAN DERIVATIVES FROM BIOMASS

The present invention relates to a method for preparing for a furan derivative from biomass, comprising step (1) of preparing 5-hydroxymethylfurfural by reacting biomass and a solid acid catalyst in butanol; and step (2) of preparing a furan derivative by reacting the butanol solution of 5-hydroxymethylfurfural, obtained in step (1), with a hydrogenation catalyst. 1. A method for preparing a furan derivative from biomass , comprising:step (1) of preparing 5-hydroxymethylfurfural by reacting biomass and a solid acid catalyst in butanol; andstep (2) of preparing a furan derivative by reacting the butanol solution of 5-hydroxymethylfurfural, obtained in step (1), with a hydrogenation catalyst.2. The method of claim 1 , wherein the furan derivative is dimethylfuran or dihydroxymethylfuran.3. The method of claim 1 , wherein the biomass is fructose claim 1 , glucose claim 1 , or both fructose and glucose.4. The method of claim 3 , wherein an isomerization catalyst is further used along with solid acid catalyst when glucose is included in the biomass.5. The method of claim 1 , wherein the solid acid catalyst is bronsted acid claim 1 , Lewis acid claim 1 , or a mixture thereof.6. The method of claim 1 , wherein the solid acid catalyst is an ion exchange resin type.7. The method of claim 1 , wherein the biomass and the butanol are used at a weight ratio of from 1:1 to 1:100.8. The method of claim 1 , wherein the butanol is 1-butanol or isobutanol.9. The method of claim 1 , wherein step (1) is performed at a temperature from 50° C. to 100° C. at ambient pressure.10. The method of claim 1 , further comprising step (1-1) claim 1 , which is to remove the solid acid catalyst and unreacted biomass from the reaction mixture of step (1) claim 1 , before step (2).11. The method of claim 10 , wherein step (1-1) is performed by filtration at a temperature from 10° C. to 50° C.12. The method of claim 1 , further comprising step (2-1) claim 1 , which is to separate the furan derivative ...

LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR USE IN THE TREATMENT OF ATROPHIC VAGINITIS

Provided herein are lipidic furan, pyrrole, and thiophene compounds, compositions, and methods using such compounds and compositions for the treatment of atrophic vaginitis. Specifically, the invention includes administering an effective amount of a compound of Formula I, I′, or I″, or a pharmaceutically acceptable composition, salt, isotopic analog, prodrug, or combination thereof, to a subject suffering from atrophic vaginitis. 4. The method of claim 3 , wherein R claim 3 , R claim 3 , R claim 3 , or Ris an alkyl radical claim 3 , an alkenyl radical claim 3 , or an alkynyl radical having a carbon chain comprising C-C.5. The method of claim 3 , wherein R claim 3 , R claim 3 , Ror Ris an alkyl radical claim 3 , an alkenyl radical claim 3 , or an alkynyl radical having a carbon chain comprising C-C.6. The method of claim 3 , wherein R claim 3 , R claim 3 , Ror Ris an alkyl radical claim 3 , an alkenyl radical claim 3 , or an alkynyl radical having a carbon chain comprising C-C.7. The method of claim 3 , wherein Ror R claim 3 , is an alkyl radical claim 3 , an alkenyl radical claim 3 , or an alkynyl radical having a carbon chain comprising C-C.8. The method of claim 3 , wherein Ror R claim 3 , is an alkyl radical claim 3 , an alkenyl radical claim 3 , or an alkynyl radical having a carbon chain comprising C-C.15. The method of claim 3 , further comprising administering an estrogenic agent.16. The method of claim 15 , wherein the estrogenic agent is Estradiol Vaginal Cream claim 15 , Estradiol Vaginal (local) claim 15 , Conjugated Estrogens claim 15 , Estradiol Transdermal claim 15 , Estradiol claim 15 , Estradiol Patch claim 15 , Estradiol topical (for use on skin) claim 15 , Estradiol and Norethindrone claim 15 , Estradiol Valerate claim 15 , Estradiol Cypionate claim 15 , Conjugated Estrogens (synthetic a) claim 15 , Conjugated Estrogens (oral) claim 15 , Esterified Estrogens claim 15 , Conjugated Estrogens and Medroxyprogesterone claim 15 , or Estropipate.17. The ...

PRODUCTION OF FURANS

The invention relates to obtaining furans from biomass. In particular, the invention relates to obtaining furans from polyols, such as tetrahydroxybutane. In accordance with the invention tetrahydroxybutane is converted to furan in the presence of a catalyst. The tetrahydroxybutane may be dissolved in a solvent such as water. 1. Method for obtaining furan comprising providing tetrahydroxybutane and converting said tetrahydroxybutane to furan in the presence of a catalyst , wherein the tetrahydroxybutane is heated in the presence of the catalyst to a temperature of at least 130° C.2. Method according to claim 1 , wherein the tetrahydroxybutane is dissolved in a solvent claim 1 , preferably a polar solvent claim 1 , more preferably a polar protic solvent claim 1 , most preferably water.3. Method according to claim 1 , wherein the tetrahydroxybutane is heated in the presence of the catalyst to a temperature of at least 150° C. claim 1 , preferably between 150 and 300° C. claim 1 , more preferably between 150 and 250° C. claim 1 , even more preferably between 175 and 225° C. claim 1 , most preferably about 220° C.4. Method according to claim 1 , wherein the tetrahydroxybutane is heated in the presence of the catalyst for a period of 1 to 60 minutes claim 1 , preferably 5 to 30 minutes claim 1 , more preferably between 10 and 20 minutes claim 1 , most preferably about 16 minutes.5. Method according to claim 1 , wherein the catalyst is an acid claim 1 , base or an anhydride claim 1 , preferably a Brønsted acid having a pKof less than 4 claim 1 , preferably less than 2 claim 1 , and is optionally immobilized on a solid support.6. Method according to claim 1 , wherein the catalyst is selected from the group consisting of sulfuric acid claim 1 , phosphoric acid claim 1 , hydrochloric acid claim 1 , hydrobromic acid claim 1 , hydroiodic acid claim 1 , acetic acid claim 1 , formic acid claim 1 , propylphosphonic anhydride and combinations thereof.7. Method according to claim 1 ...

METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND

Disclosed is a method for preparing a 2,5-disubstituted furan compound. The 2,5-disubstituted furan compound is prepared in a simple, convenient and highly efficient way by reacting 2,3-dicarboxylic anhydride-7-oxabicyclo[2.2.1]hept-5-ene and/or furan with an acylating reagent and/or an alkylating reagent. The preparation method is simple and efficient, has a short process and less by-products, and the 2,5-disubstituted furan compound prepared by using the method has a high purity, and can satisfy the requirements for being used as a raw material for engineering plastics, such as high-performance polyesters, epoxy resins, polyamides, polyurethanes and the like, and as a chemical raw material and a pharmaceutical intermediate raw material. 1. A method for preparing a 2 ,5-disubstituted furan compound , wherein the 2 ,5-disubstituted furan compound is prepared by reacting 2 ,3-dicarboxylic anhydride-7-oxabicyclo[2.2.1]hept-5-ene and/or furan with an acylating reagent or an alkylating reagent.2. The method according to claim 1 , wherein the acylating reagent is an anhydride and/or an acyl halide; and the alkylating reagent is at least one selected from halogenated alkanes.4. The method according to claim 2 , wherein the halogenated alkane is at least one selected from the compounds with the chemical structure formula represented by Formula III:{'br': None, 'sup': '4', 'R—X\u2003\u2003Formula III'}{'sup': '4', 'wherein, Ris an alkyl group with carbon atoms from 1 to 20; and X is selected from fluorine, chlorine, bromine, iodine.'}6. The method according to claim 1 , wherein the 2 claim 1 ,5-disubstituted furan compound is at least one selected from 2 claim 1 ,5-diacetylfuran claim 1 , 2 claim 1 ,5-dihaloacetylfuran claim 1 , 2 claim 1 ,5-dimethylfuran claim 1 , 2 claim 1 ,5-diethylfuran.7. The method according to claim 1 , wherein the reaction of 2 claim 1 ,3-dicarboxylic anhydride-7-oxabicyclo[2.2.1]hept-5-ene and/or furan with the acylating reagent is performed at a ...

Method for producing furan compound and furfural composition

The present invention is aimed to provide an industrially advantageous method for producing a furan compound, in which a furan compound can be efficiently obtained in a high selectivity from a furfural compound. The present invention is concerned with a method for producing a furan compound including feeding, as a raw material, a furfural composition containing a furfural compound into a reactor and subjecting to a decarbonylation reaction in the presence of a catalyst to obtain a furan compound as a product, wherein a furfural dimer concentration in the furfural composition is 1,000 ppm by weight or less, and a peroxide value in the furfural composition is 0.01 mEq/kg or more and 1.0 mEq/kg or less.

PROCESS FOR THE PREPARATION OF 2, 5-DIMETHYLEFURAN AND FURFURYL ALCOHOL OVER RUTHENIUM SUPPORTED CATALYSTS

The present invention relates to an improved process for the preparation of 2.5-dimethylfuran and furfuryl alcohol over ruthenium supported catalysts. Further, the present invention disclosed a process for the selective hydrogenolysis of biomass derived 5-hydroxymethylfurfural (HMF) into 2.5-dimethylfuran (DMF) using Ru nanoparticles supported on NaY zeolite as a catalyst. 2. The process as claimed in claim 1 , wherein transition metals are selected from Cu claim 1 , Ni claim 1 , Re claim 1 , Cr claim 1 , Mn claim 1 , Fe or Co in the range of 1-10 wt % of the catalyst.3. The process as claimed in claim 1 , wherein ruthenium catalyst supported on NaY zeolite is selected from 2% Ru—NaY claim 1 , 2% Ru—K—NaY claim 1 , 2% Ru—Rb—NaY claim 1 , 2% Ru—Cs—NaY claim 1 , 2% Ru—Mg—NaY claim 1 , 2% Ru—Ca—NaY claim 1 , 2% Ru—Sr—NaY claim 1 , 2% Ru—Ba—NaY claim 1 , Ru—Cu [1:3]/NaY.4. The process as claimed in claim 1 , wherein the solvent is tetrahydrofuran.5. The process as claimed in claim 1 , wherein compounds of general formula 1 is selected from the group consisting of 2 claim 1 ,5-dimethylfuran or furfuryl alcohol.6. The process as claimed in claim 1 , wherein compounds of general formula 2 is selected from the group consisting of 5-hydroxymethylfurfural or furfural.7. The process as claimed in claim 1 , wherein mole ratio of 5-hydroxymethylfurfural and ruthenium catalyst is in the range of 150-250.8. The process as claimed in claim 1 , wherein conversion of compounds of general formula 2 is in the range of 90-100 mol %.9. The process as claimed in claim 1 , wherein yield of compounds of general formula 1 is in the range of 75-90 mol %. The present invention relates to an improved process for the preparation of 2,5-dimethylfuran and furfuryl alcohol over ruthenium supported catalysts. Particularly, the present invention provides a process for the selective hydrogenolysis of biomass derived 5-hydroxymethylfurfural (HMF) into 2,5-dimethylfuran (DMF) using Ru nanoparticles ...

METHODS OF FORMING AROMATIC CONTAINING COMPOUNDS

Methods that include acylating an aromatic containing compound by reacting the aromatic containing compound with an anhydride containing compound to form an acylated aromatic containing compound. 1. A method comprising:acylating an aromatic containing compound by reacting the aromatic containing compound with an anhydride containing compound to form an acylated aromatic containing compound.2. The method according to claim 1 , wherein the aromatic containing compound is a furan containing compound.3. The method according to further comprising subjecting the acylated aromatic compound to hydrogenation to replace the ketone functionality with a methylene.4. (canceled)5. (canceled)6. (canceled)7. The method according to further comprising functionalizing the acylated aromatic containing compound with a hydrophilic moiety.8. The method according to claim 7 , wherein the functionalization occurs via sulfonation.9. (canceled)10. (canceled)11. The method according to further comprising subjecting the acylated aromatic containing compound to a cycloaddition reaction.12. The method according to claim 11 , wherein the cycloaddition is a diels-alder reaction.13. The method according to claim 12 , wherein the cycloaddition occurs by reacting the acylated aromatic containing compound with ethylene (CH).14. (canceled)15. (canceled)16. The method according to further comprising adding an alkyl group to the group added via acylation of the aromatic containing compound.17. The method according to claim 16 , wherein the alkyl group is added to the group added via acylation before hydrogenation to replace the ketone group with a methylene group.18. The method according to claim 17 , wherein adding the alkyl group to the group added via acylation is done by an aldol-condensation.19. The method according to claim 7 , wherein the functionalization of the acylated aromatic containing compound occurs after hydrogenation of the acylated aromatic compound claim 7 , or before hydrogenation of ...

CATALYST AND CATALYTIC PROCESS FOR THE ETHERIFICATION/REDUCTION OF FURFURYL DERIVATIVES TO TETRAHYDROFURFURYL ETHERS

The invention relates to a method for producing tetrahydrofurfuryl ethers, characterised in that it involves carrying out consecutive etherification/reduction reactions based on a compound containing at least one furan ring, in the presence of at least one alcohol and at least one catalyst, optionally in the presence of H. The catalytic process can be carried out in a cascade reaction (“one-pot”), operating under soft reaction conditions and without a solvent. 3. The process according to claim 2 , wherein a compound of tetrahydro-furfuryl ether type having 6 to 24 carbon atoms is obtained.4. The process according to wherein the furan compound contains a furan ring (mono-furan).5. The process according to claim 4 , wherein the mono-furan compound is selected from furfural claim 4 , 5-hydroxymethylfurfural claim 4 , 5-methoxymethyl furfural claim 4 , 5-ethoxymethyl furfural claim 4 , and combinations thereof.7. The process according to claim 6 , wherein the alcohol is selected from: an aliphatic primary alcohol having 2 to 12 carbon atoms claim 6 , an aliphatic secondary alcohol having 2 to 12 carbon atoms claim 6 , and combinations thereof.8. The process according to claim 1 , wherein the hydrogen is derived from a source selected from molecular hydrogen claim 1 , a gas mixture containing hydrogen claim 1 , and combinations thereof.9. The process according to wherein the catalyst is selected from:a) a metallic catalyst “CAT A” comprising one or more noble metals, or one or more transition metals, or one or more of its salts or complexes, and combinations thereof, with the aforementioned “CAT A” being supported, or included in a carbonaceous type solid or in the structure of an inorganic matrix;b) a metallic catalyst “CAT B” comprising one or more transition metals, their salts or complexes, included within or supported on an inorganic matrix structure;c) a metallic catalyst “CAT C” comprising at least one noble metal and one or more transition metals, or one or more ...

Methods for preparing alkylfurans

Provided herein are methods for preparing alkylfurans, such as 2,5-dialkylfurans and 2-alkylfurans. Furfural or 5-alkylfurfural can be reacted with aniline or diaminobenzene, or derivatives thereof, to form the corresponding imine, which can be reduced to form alkylfurans and to regenerate the aniline or diaminobenzene, or derivatives thereof. The alkylfuran may be, for example, 2,5-dimethylfuran or 2-methylfuran.

METHODS OF PRODUCING ALKYLFURANS

Provided herein are methods of producing dialkylfurans, such as 2,5-dimethylfuran, and other alkyl furans, such as 2-methylfuran. For example, 2,5-dimethylfuran may be produced by reducing (5-methylfuran-2-yl)methanol or 2-(chloromethyl)-5-methylfuran. 130-. (canceled)32. A method of producing 5-methylfuran-2-carbaldehyde , the method comprising:(i) providing 5-(chloromethyl)furfural; and hydrogen,', 'a catalyst, and', 'an amide reagent, or a urea reagent, or a combination thereof., '(ii) converting the 5-(chloromethyl)furfural to 5-methylfuran-2-carbaldehyde in the presence of'}35. The method of claim 32 , wherein the amide reagent is N claim 32 ,N-dimethylformamide.40. The method of claim 32 , wherein the catalyst comprises palladium.41. The method of claim 40 , wherein the catalyst further comprises a solid support.42. The method of claim 32 , wherein the catalyst is Pd/C claim 32 , Pd/AlO claim 32 , or PdCl.43. The method of claim 32 , further comprising converting the 5-(chloromethyl)furfural to 5-methylfuran-2-carbaldehyde in the presence of an aromatic reagent.44. The method of claim 43 , wherein the aromatic reagent comprises at least one mono-aryl compound claim 43 , at least one di-aryl compound claim 43 , or at least one tri-aryl compound claim 43 , or any mixtures thereof.45. The method of claim 44 , wherein the at least one mono-aryl compound is toluene claim 44 , or para-xylene claim 44 , or any combination thereof.46. The method of claim 32 , further comprising isolating the 5-methylfuran-2-carbaldehyde.47. A method claim 32 , comprising:{'claim-ref': {'@idref': 'CLM-00032', 'claim 32'}, 'producing 5-methylfuran-2-carbaldehyde according to the method of ;'}isolating the 5-methylfuran-2-carbaldehyde; andconverting the isolated 5-methylfuran-2-carbaldehyde to 2,5-dimethylfuran. This application claims the benefit of U.S. Provisional Patent Application Ser. No. 61/866,491, filed Aug. 15, 2013, the disclosure of which is hereby incorporated herein by ...

Method and System for Hybrid Catalytic Biorefining of Biomass to Methylated Furans and Depolymerized Technical Lignin

A method is disclosed for converting biomass into a fuel additive, the method comprising: liquefying the biomass to form a liquor; neutralizing the liquor; precipitating lignin out of the liquor; extracting furfural (FF) and 5-hydroxymethylfurfural (HMF) from the liquor; and hydrodeoxygenating (HDO) the extracted furfurals over a Cu—Ni/TiOcatalyst. The catalyst for hydrodeoxygenating (HDO) furfural (FF) and 5-hydroxymethylfurfural (HMF) to methylated furans comprises copper-nickel (Cu—Ni) particles supported on titanium dioxide (TiO), and wherein the copper-nickel particles form core-shell structures in which copper (Cu) is enriched at a surface of the catalyst. 1. A catalyst for hydrodeoxygenating (HDO) furfural (FF) and 5-hydroxymethylfurfural (HMF) to methylated furans , the catalyst comprising:{'sub': '2', 'copper-nickel (Cu—Ni) particles supported on titanium dioxide (TiO), and wherein the copper-nickel particles form core-shell structures in which copper (Cu) is enriched at a surface of the catalyst.'}2. The catalyst according to claim 1 , wherein a concentration of nickel (Ni) at the surface of the catalyst is reduced claim 1 , thereby allowing the Ni to promote Cu reactivity without compromising selectivity.3. The catalyst according to claim 1 , wherein the Cu—Ni particles are between 2.5 wt % to 20 wt % Cu and between 0.5 wt % to 20 wt % Ni.4. The catalyst according to claim 1 , wherein the Cu—Ni particles are 2.5 wt % Cu-0.5 wt % Ni claim 1 , 2.5 wt % Cu-1.5 wt % Ni claim 1 , 5 wt % Cu-3 wt % Ni claim 1 , 5 wt % Cu-5 wt % Ni claim 1 , 10 wt % Cu-5 wt % Ni claim 1 , 10 wt % Cu-10 wt % Ni claim 1 , 15 wt % Cu-5 wt % Ni claim 1 , 15 wt % Cu-10 wt % Ni claim 1 , 15 wt % Cu-15 wt % Ni claim 1 , 20 wt % Cu-15 wt % Ni or 20 wt % Cu-20 wt % Ni.5. A method of synthesizing a catalyst for hydrodeoxygenating furfural (FF) and 5-hydroxymethylfurfural (HMF) to methylated furans claim 1 , the method comprising:synthesizing monometallic copper (Cu) catalysts and ...

Process for the preparation of substituted indenes

The compounds of the formula I or Ia ##STR1## in which R 1 is alkyl, aryl, alkoxy, alkenyl, arylalkyl, alkylaryl, aryloxy, fluoroalkyl, halogenoaryl, alkynyl, trialkylsilyl or a heteroaromatic radical, R 2 , R 3 and R 4 , in addition to hydrogen, have the meanings given under R 1 and R 5 is hydrogen, alkyl, fluoroalkyl or alkenyl, can be obtained in a one-stage process by reaction of a compound II ##STR2## with (substituted) cyclopentadiene in the presence of a base. The compounds I and Ia are suitable as ligands for metallocene complexes which are used as catalysts in olefin polymerization.

Verfahren zur herstellung substituierter indene

Methods for preparing alkylfurans

Method for producing substituted indene

一种基于蒽的半导体材料、制备方法及有机场效应晶体管

本发明公开一种基于蒽的半导体材料、制备方法及有机场效应晶体管，其中，所述半导体材料的分子结构式为 或 ，其中，所述R为碳原子数为1‑12的烷基链。本发明提供的有机半导体材料以蒽为母核，两端桥连呋喃或苯并呋喃基团，该类有机半导体材料具有较高电荷迁移率且性能稳定，其不仅丰富了有机半导体材料的类型，更有助于有机场效应晶体管的进一步发展。

一种航空煤油前体的制备方法

本发明涉及一种航空煤油前体的制备方法，将糠醛、2‑甲基呋喃和固体路易斯酸催化剂混合置于密闭反应器中，催化反应制备获得C15呋喃三聚体；催化反应条件为：反应温度为100‑150℃，无溶剂添加，反应时间7‑16小时。糠醛和2‑甲基呋喃摩尔比例为1：（2‑3），糠醛和催化剂质量比为（5‑20）:1，本发明采用以金属Zr为核心金属元素的固体路易斯酸催化剂缩合反应。该催化剂具有活性高、稳定性好，能够多次重复利用，反应产物产率高，选择性高等优点。同时，该类路易斯酸型催化剂不产生酸质子，避免了在高温下催化剂对设备腐蚀，反应后处理方便，对环境友好。

一种催化加氢5-羟甲基糠醛制备2,5-二甲基呋喃的方法

本发明涉及一种催化加氢5‑羟甲基糠醛制备2,5‑二甲基呋喃的方法，在该方法中以一种钴与石墨烯复合材料(Co/rGO)为催化剂。Co/rGO催化剂无需还原预处理，在140℃‑200℃和1‑2MPa氢气压力下，HMF的转化率可达100％，DMF的收率超过90％。Co/rGO催化剂比Pt、Pd等贵金属类催化剂廉价，只解离C＝O/C—O键，不破坏呋喃环以及C—C键，因此对DMF有很高的选择性，且不需要预还原处理，具有工业应用价值。

Process for the preparation of substituted indenes

Process for the preparation of a substituted indenes

Process for the preparation of substituted indenes

Abstract of the disclosure Process for the preparation of substituted indenes The compounds of the formula I or Ia ( I ), ( Ia) in which R1 is alkyl, aryl, alkoxy, alkenyl, arylalkyl, alkylaryl, aryloxy, fluoroalkyl, halogenoaryl, alkynyl, trialkylsilyl or a heteroaromatic radical, R2, R3 and R4, in addition to hydrogen, have the meanings given under R1 and R5 is hydrogen, alkyl, fluoroalkyl or alkenyl, can be obtained in a one-stage process by reaction of a compound II

PROCEDURE FOR THE MANUFACTURE OF SUBSTITUTED ITEMS.

LA COMPOSICION DE LA FORMULA I O IA DONDE R ELEVADO 1 SIGNIFICA ALQUILO, ARILO, ALCOXI, ALQUENILO, ARILALQUIL, ALQUILARIL, ARILOXI, FLUORALQUIL, HALOGENARIL, ALQUINIL, TRIALQUILSILIL O UN RESTO DE AROMA ETEREO, R (AL CUADRADO) , R ELEVADO 3 Y R ELEVADO 4 POSEEN EL SIGNIFICADO MENCIONADO EN R ELEVADO 1 JUNTO CON HIDROGENO Y R ELEVADO 5 SIGNIFICA HIDROGENO, ALQUILO, FLUORALQUILO ALQUENILO Y PUEDEN OBTENERSE EN UN PROCESO DE UNA SOLA ETAPA MEDIANTE LA TRANSFORMACION DE LA COMPOSICION II CON SUSTITUYENTES CICLOPEDIEN EN PRESENCIA DE UNA BASE. LA COMPOSICION I, CONCRETAMENTE IA, SIRVE COMO LIGANTE PARA LOS COMPLEJOS DE METALOCEN, QUE SE UTILIZAN COMO CATALIZADORES EN CASO DE LA OLEFINPOLIMERIZACION. THE COMPOSITION OF THE IO IA FORMULA WHERE R ELEVATED 1 MEANS ALKYL, ARYL, ALCOXY, ALKYNYL, ARILALKYL, ALKYLARYL, ARYLOXY, FLUORALKYL, HALOGENARIL, ALKYL, TRIALQUILSILIL OR A REST OF EARO ELEVATED 4 POSSESS THE MEANING MEANING IN R ELEVATED 1 TOGETHER WITH HYDROGEN AND R ELEVATED 5 MEANS HYDROGEN, RENT, FLUORALKYL ALKYLENE AND MAY BE OBTAINED FROM A SINGLE STAGE PROCESS BY TRANSFORMATION COMPOSITION I, SPECIFICALLY IA, SERVES AS A BINDER FOR METALOCEN COMPLEXES, WHICH ARE USED AS CATALYSTS IN CASE OF OLEFINPOLIMERIZACION.

Process for the preparation of substituted indenes

Process for the preparation of substituted indenes

Process for the preparation of substituted indenes

Die Verbindungen der Formel I oder Ia worin R¹ Alkyl, Aryl, Alkoxy, Alkenyl, Arylalkyl, Alkylaryl, Aryloxy, Fluoralkyl, Halogenaryl, Alkinyl, Trialkylsilyl oder einen heteroaromatischen Rest bedeutet, R², R³ und R⁴ neben Wasserstoff die unter R¹ genannten Bedeutungen besitzen und R⁵ Wasserstoff, Alkyl, Fluoralkyl oder Alkenyl bedeutet, können in einem einstufigen Verfahren durch Umsetzung einer Verbindung II mit (subst.) Cyclopentadien in Gegenwart einer Base erhalten werden. Die Verbindungen I bzw. Ia eignen sich als Liganden für Metallocenkomplexe, die als Katalysatoren bei der Olefinpolymerisation Verwendung finden. The compounds of formula I or Ia wherein R¹ Is alkyl, aryl, alkoxy, alkenyl, arylalkyl, alkylaryl, aryloxy, fluoroalkyl, haloaryl, alkynyl, trialkylsilyl or a heteroaromatic radical, R², R³ and R⁴ in addition to hydrogen have the meanings mentioned under R¹ and R⁵ Hydrogen, alkyl, fluoroalkyl or alkenyl means can in a one-step process by reacting a compound II can be obtained with (subst.) cyclopentadiene in the presence of a base. The compounds I and Ia are suitable as ligands for metallocene complexes which are used as catalysts in olefin polymerization.

Process for the preparation of a substituted indenes

The compounds of the formula I or Ia <IMAGE> (I) <IMAGE> (Ia) in which R1 is alkyl, aryl, alkoxy, alkenyl, arylalkyl, alkylaryl, aryloxy, fluoroalkyl, halogenoaryl, alkynyl, trialkylsilyl or a heteroaromatic radical, R2, R3 and R4, in addition to hydrogen, have the meanings given under R1 and R5 is hydrogen, alkyl, fluoroalkyl or alkenyl, can be obtained in a one-stage process by reaction of a compound II <IMAGE> with (substituted) cyclopentadiene in the presence of a base. The compounds I and Ia are suitable as ligands for metallocene complexes which are used as catalysts in olefin polymerization.

一种利用5-羟甲基糠醛选择性加氢制备2，5-呋喃二甲醇的方法

本发明公开了一种利用5‑羟甲基糠醛选择性加氢制备2，5‑呋喃二甲醇的方法，将5‑羟甲基糠醛、催化剂CuNPs@ZIF‑8和乙醇加入不锈钢密闭反应器中，充入H 2 ，于120‑150℃的温度并1‑4MPa的压力下反应0.1‑5h。本发明以CuNPs@ZIF‑8为催化剂，该催化剂不仅比表面积大、纳米铜分散度高和氢气吸附性能好而且制备简单，价格廉价且可重复利用。本发明克服了现有研究中使用贵金属为催化剂价格昂贵和非贵金属为催化剂效率低的难题。

Methods of producing alkylfurans

Method for production of 1-{2-[(5-dimethylaminomethyl-2-furyl)-methylthio] -ethyl}-amino-1-methyl- -amino-2-nitroethylene

FIELD: medicine. SUBSTANCE: diketene-imine derivatives having formula (I) is used as reagent 1, methylamine being used as reagent 2. Their interaction is carried out in the medium of solvent at room temperature. Methylamine is used in gaseous state or in aqueous solution, preferred quality of said solution being 10 moles of 40 mass % solution. EFFECT: improves efficiency of the method. 3 cl рзЗ9с$0с ПЧ Го РОССИЙСКОЕ АГЕНТСТВО ПО ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ (19) ВИ” 2 032 681 ' 13) СЛ 5 МК С 070 307/52 12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ РОССИЙСКОЙ ФЕДЕРАЦИИ (21), (22) Заявка: 5010152/04, 06.11.1991 (30) Приоритет: 09.11.1990 НЦ 7074/90 (46) Дата публикации: 10.04.1995 (56) Ссылки: Патент Великобритании М 1565966, кл. (71) Заявитель: Рихтер Гедеон Ведьесети Дьяра РТ (НО) (72) Изобретатель: Андор Йесенски[НЧ], Бела Лошонци[Н\], Мария Цейх[НУ], Ласло Годо[НУ], Бела Штефко[НУ], Тамаш Бенцик[ НУ], Мария Пергер[НУ], Ласло С 070 307/52, опублик.1980 Патент США М Херманн[НУ], Габор Хаваши[НУ], Петер <“ 4491961 ‚ КЛ. С 070 307/52, опублик.1985.Патент Калвин[НУ], Ласло Штефан[НЧУ], Тибор О США М 4440938, кл. С 070 307/52, Бало[[НУ], Эндре Кастрейнер[Н\], Нандор опублик.1983.ЕР М 55625, кл. С 070 307/52, Макк[НУ], Лайош Толди[НУ], Эстер опублик.1982.ЕР М 219225, кл. С 070 307/42, Дишлер[НУ], Арпад Лазар[НУ], Петер опублик.1987. Патент ЗЧ М 1419519, кл. С 070 Матюш[НУ], Эмилия УшкертНУ] <= 307/50, опублик.1985. (73) Патентообладатель: со Рихтер Гедеон Ведьесети Дьяра РТ (НО) ‹о < (54) СПОСОБ ПОЛУЧЕНИЯ 1-(2-[(5-ДИМЕТИЛАМИНОМЕТИЛ-2-ФУРИЛ) -МЕТИЛТИО]-ЭТИЛ)-АМИНО-1- МЕТИЛАМИНО-2-НИТРОЭТИЛЕНА © (57) Реферат: Предпочтительно используют 10 молей 40 © Использование: в медицине в качестве мас.% водного раствора меламина. Структура с! антагониста Н-2 рецептора. Сущность соединения ф-лы 1. 2 з.п.ф-лы. изобретения: НС продукт-1-[2-[(5-диметиламинометил-2-фурил) З“ НС Н -$-(СН } -М-С=СН-№ -метилтиос]-этил] -амино-1 -метиламино 2 2 22 2 — -2-нитроэтилен. т.пл. 71 - 73°С. Выход 94%. Н.С а’ ...

A kind of normal temperature and pressure reducing carbonyl is the method for methylene

本发明公开了一种常温常压还原羰基为亚甲基的方法，包括如下步骤：将羰基化合物、氮掺杂碳材料负载钯催化剂和溶剂加入反应容器中，其中羰基化合物与氮掺杂碳材料负载钯催化剂的比为1～5mol：10～40g，通入氢气，在常温常压下反应0.5～20h，即可催化加氢还原羰基为亚甲基，该反应的反应式如下：

A kind of furfural is converted into 2- methylfuran method for preparing catalyst

一种糠醛转化为2‑甲基呋喃催化剂制备方法，涉及一种催化剂制备方法，本发明具体步骤包括：可溶性Cu盐以及可溶性助剂盐配制成溶液，然后加入硅溶胶或硅酸酯并搅拌均匀，再将碳酸铵或者尿素等加入上述溶液，并密闭搅拌一定时间，然后在一定温度条件下水热反应，再在一定温度超声波辅助下加热蒸发，调控其pH值达到一定值，进一步将沉淀洗涤、干燥和焙烧，最后制得CuO‑M/SiO 2 催化剂,（M为Zr、Mg等）。其中CuO的质量百分比为10%‑50%，SiO 2 的质量百分比为50%‑90%，金属助剂的质量百分比为1%‑6%。该新的糠醛合成2‑甲基呋喃催化剂制备方法大大提高了催化剂活性、选择性及稳定性。

A method for preparing furan derivatives from biomass

The present invention relates to a process for producing 5-hydroxymethylfurfural by reacting butanol with a biomass and a solid acid catalyst; And a second step of reacting a butanol solution of 5-hydroxymethyl furfural obtained from the first step with a hydrogenation catalyst to prepare a furan derivative. The present invention also relates to a method for producing a furan derivative from a biomass.

Post metallocene ligand compound, method for preparing the same, organometallic compound and method for preparing the same

본 발명은 포스트 메탈로센형 리간드 화합물, 이의 제조방법, 유기 금속 화합물 및 이의 제조방법에 관한 것이다. 본 발명의 유기 금속 화합물은 종래의 시클로펜타디엔 고리에서 벗어나 퓨란 구조를 기본 골격으로 가지는 포스트 메탈로센용 화합물이다.

A kind of method that normal pressure gas phase catalysis 5 hydroxymethyl furfural adds hydrogen to prepare 2,5- dimethyl furan

一种常压气相催化5‑羟甲基糠醛加氢制备2,5‑二甲基呋喃的方法，其特征在于，采用Cu基负载型催化剂，以氢气为氢源，将5‑羟甲基糠醛和有机溶剂配制成5‑羟甲基糠醛溶液，在常压、气相和适宜的反应条件下对所述5‑羟甲基糠醛进行选择性加氢，得到2,5‑二甲基呋喃。本发明提供的一种常压气相催化5‑羟甲基糠醛加氢制备2,5‑二甲基呋喃的方法的有益之处主要表现为以下几个方面：采用非贵金属的Cu基负载型催化剂，活性高，选择性好，成本低；采用常压气相连续的加氢反应过程，操作简单、反应条件温和，可大大降低能耗和生产成本；催化剂无Cr等有害元素，有机溶剂循环利用，过程安全环保。

Catalyst, manufacturing method of catalyst, and manufacturing method of 2,5-dimethylfuran using catalyst

The present invention relates to a catalyst, a manufacturing method of the catalyst, and a manufacturing method of 2,5-dimethylfuran using the catalyst, wherein the catalyst of the present invention contains sulfonated graphene oxide, a metal organic framework (MOF) compound disposed on the surface of the sulfonated graphene oxide and containing a first metal, and a second metal supported on the metal organic framework compound. According to the present invention catalysts containing various functional sites can be provided.

Insecticide composition

Patent RU2016142388A3

`”ВУ“” 2016142388” АЗ Дата публикации: 09.10.2018 Форма № 18 ИЗИМ-2011 Федеральная служба по интеллектуальной собственности Федеральное государственное бюджетное учреждение 5 «Федеральный институт промышленной собственности» (ФИПС) ОТЧЕТ О ПОИСКЕ 1. . ИДЕНТИФИКАЦИЯ ЗАЯВКИ Регистрационный номер Дата подачи 2016142388/04(067869) 26.03.2015 РСТ/ЕР2015/056657 26.03.2015 Приоритет установлен по дате: [ ] подачи заявки [ ] поступления дополнительных материалов от к ранее поданной заявке № [ ] приоритета по первоначальной заявке № из которой данная заявка выделена [ ] подачи первоначальной заявки № из которой данная заявка выделена [ ] подачи ранее поданной заявки № [Х] подачи первой(ых) заявки(ок) в государстве-участнике Парижской конвенции (31) Номер первой(ых) заявки(ок) (32) Дата подачи первой(ых) заявки(ок) (33) Код страны 1. 14162689.5 31.03.2014 ЕР* Название изобретения (полезной модели): [Х] - как заявлено; [ ] - уточненное (см. Примечания) СПОСОБ ПОЛУЧЕНИЯ ФУРАНА ИЗ ФУРФУРОЛА Заявитель: ШЕЛЛ ИНТЕРНЭШНЛ РИСЕРЧ МААТСХАППИИ Б.В., М1. 2. ЕДИНСТВО ИЗОБРЕТЕНИЯ [Х] соблюдено [ ] не соблюдено. Пояснения: см. Примечания 3. ФОРМУЛА ИЗОБРЕТЕНИЯ: [Х] приняты во внимание все пункты (см. п см. Примечания [ ] приняты во внимание следующие пункты: р [ ] принята во внимание измененная формула изобретения (см. Примечания) 4. КЛАССИФИКАЦИЯ ОБЪЕКТА ИЗОБРЕТЕНИЯ (ПОЛЕЗНОЙ МОДЕЛИ) (Указываются индексы МПК и индикатор текущей версии) (070 307/36 (2006.01) 5. ОБЛАСТЬ ПОИСКА 5.1 Проверенный минимум документации РСТ (указывается индексами МПК) С07р 307/36 5.2 Другая проверенная документация в той мере, в какой она включена в поисковые подборки: 5.3 Электронные базы данных, использованные при поиске (название базы, и если, возможно, поисковые термины): Езрасепес, Соозе Раеп$, РаеагсЬ 6. ДОКУМЕНТЫ, ОТНОСЯЩИЕСЯ К ПРЕДМЕТУ ПОИСКА Кате- Наименование документа с указанием (где необходимо) частей, Относится к гория* относящихся к предмету поиска пункту формулы № 1 2 3 У ]Р 2013159594 А (МПЗОВЬНЕ ...

METHOD FOR PRODUCING FURAN AND ITS DERIVATIVES

РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2016 142 374 A (51) МПК C07D 307/36 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2016142374, 26.03.2015 (71) Заявитель(и): ШЕЛЛ ИНТЕРНЭШНЛ РИСЕРЧ МААТСХАППИЙ Б.В. (NL) Приоритет(ы): (30) Конвенционный приоритет: 31.03.2014 EP 14162654.9 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 31.10.2016 R U (43) Дата публикации заявки: 03.05.2018 Бюл. № 13 (72) Автор(ы): ВАДМАН Сипке Хидде (NL), ЛАНЖ Жан Поль Андре Мари Жозеф Гислен (NL) (86) Заявка PCT: (87) Публикация заявки PCT: WO 2015/150238 (08.10.2015) A Адрес для переписки: 129090, Москва, ул. Большая Спасская, д. 25, строение 3, ООО "Юридическая фирма Городисский и Партнеры" R U (57) Формула изобретения 1. Способ обработки первого жидкого потока фурана, содержащего фуран и монооксид углерода, причем указанный способ включает этапы: i) контакт упомянутого первого потока фурана с первым СО-обедненным газообразным потоком; и ii) отбор, по меньшей мере, части монооксида углерода из первого потока фурана в первый газообразный поток с получением второго жидкого потока фурана, содержащего монооксид углерода в количестве, меньшем, чем в первом потоке фурана, и второго газообразного потока, обогащенного СО. 2. Способ по п.1, в котором первый СО-обедненный газообразный поток, включает в себя один или более газов из группы, состоящей из водорода, азота, двуокиси углерода, водяного пара и метана. 3. Способ по п.2, отличающийся тем, что первый СО-обедненный газообразный поток содержит водород. 4. Способ по любому из пп. 1-3, в котором первый СО обедненный газообразный поток содержит не более 10 об.% CO. 5. Способ по любому из пп. 1-4, где данный способ дополнительно включает этапы: i) осуществления контакта второго потока фурана с водородом в присутствии катализатора гидрирования с получением потока продуктов реакции гидрирования, включающим THF, NBA и/или 1,4-BDO и водород; Стр.: 1 A 2 0 1 6 1 4 2 3 7 4 (54) ...

Method of producing furan

Изобретение касаетс  кислородных гетероциклических соединений, в частности фурана

Heteropolyacid catalyst supported on metal oxide, method for preparing the same, and method for polymerization reaction of furan compound using the same

본 명세서에는 금속산화물 담체에 담지된 헤테로폴리산 촉매, 이의 제조방법 및 이를 이용한 퓨란계 화합물의 중합 방법이 개시된다. 상기 헤테로폴리산 촉매는 높은 수율로 퓨란계 화합물로부터 15개 이상의 탄소 원자를 포함하는 탄화수소 화합물을 제조하는 효과가 있다.

Cyclopropane carboxylic acids as insecti - cides

NEW VEGETABLE OIL COMPOUNDS FOR USE IN THE PHARMACEUTICAL AND COSMETIC INDUSTRY, PARTICULARLY FOR THE INHIBITION OF CELL GROWTH

The invention concerns a compound of formula (I) wherein: R' is H or a carboxylic acid acyl radical (a); R is a C13-C21 hydrocarbon chain capable of comprising 1 to 4 ethenoid or acetylene unsaturations.

Manufacturing process for furfuryl alcohol and methylfuran

Patent FR2201036A1

Production of furan, for use as intermediate in thiophene synthesis, by dehydrobromination of dibromotetrahydrofuran in presence of base and in organic solvent

The process comprises the stage of dehydrobromination of 3,4-dibromotetrahydrofuran, in presence of base and in organic solvent medium, and preferably also in presence of phase transfer agent, in amount up to 20 mol. % (preferably 1-5 mol. %) in relation to 3,4-dibromotetrahydrofuran. The molar ratio of base to 3,4-dibromotetrahydrofuran is 2-8, preferably 2.5-3.5.

Bactericides and intermediates prodnfurans

Furans of formula (I): in which R1 and R2 are H, aliphatic, araliphatic or aromatic, are produced by cyclisation of 1,4-dicarbonyl of formula (II), in the presence of HI, HBr or HF as catalyst. The cpds. are bactericides, hardeners and intermediates for dyes, pesticides, solvents, paint auxiliaries and perfumes.

IMPROVED DECARBONYLATION PROCESS FOR FURFURAL IN ORDER TO OBTAIN FURANNE AND DECARBONYLATION CATALYST FOR ITS IMPLEMENTATION

Method for preparing 2,5-dimethyl furan

本发明提供了一种2,5-二甲基呋喃的制备方法，包括以下步骤：在镍系金属催化剂的作用下，将5-羟甲基糠醛在溶剂中进行氢解反应，得到2,5-二甲基呋喃；所述镍系金属催化剂为负载型双金属催化剂；所述镍系金属催化剂的有效活性成分包括镍和钨。本发明提供的方法采用以镍和钨为有效成分的镍系金属催化剂催化HMF进行氢解，得到DMF，镍成分具有较好的加氢能力，能够使醛基基团加氢成为羟甲基基团；钨成分具有较好的路易斯（Lewis）酸性，能够促进HMF氢解过程中碳-氧键的断裂，使羟甲基基团转化成甲基基团；在镍和钨的双重作用下，能够将HMF高效、高选择性的转化为DMF，使DMF的产率较高。

Bifunctional graphene oxide catalyst, and preparation method and application thereof

本发明公开了一种双功能氧化石墨烯催化剂及其制备方法和应用，制备方法为：第一步是将氧化石墨烯通过加入有机酸磺化后，得到具有酸活性中心的单功能化氧化石墨烯，第二步将贵金属纳米颗粒原位固定在已磺化的氧化石墨烯的碳纳米片上，比现有双功能催化剂的合成方法更简便。双功能氧化石墨烯催化剂带有双催化活性中心(酸活性中心和贵金属活性中心)，能提供合适的酸度和高效的氧化还原位点，该催化剂除了应用于果糖一锅法催化转化制备2,5‑二甲酰呋喃反应中，还能应用在醚化‑氧化反应、转酯化‑加氢反应和脱水‑加氢反应，双功能氧化石墨烯催化剂通过对两个活性中心空间结构的调控，提高反应催化活性和产物选择性。

A kind of catalyst and preparation method for being catalyzed 5 hydroxymethylfurfural selective hydrogenation deoxidations and preparing 2,5 dimethyl furans

本发明公开了一种催化5‑羟甲基糠醛选择性加氢脱氧制备2,5‑二甲基呋喃的催化剂及制备方法，该催化剂为基于同一氧化物的金属‑酸双功能催化剂，通过共沉淀法合成，加入聚乙烯吡咯烷酮提高其稳定性；通过改变不同还原温度，还原时间改变催化剂中Co‑CoOx的比例，得到的催化剂的比表面积大，具有合适的孔径分布，实现金属‑酸双功能催化，催化5‑羟甲基糠醛转化为2,5‑二甲基呋喃，反应活性高，选择性高，稳定性好，5‑羟甲基糠醛转化率达100％，2,5‑二甲基呋喃选择性达83.27％。

Propargylic acetylenic derivs - metallised and reacted with carbonyl cpds to form useful inters

Cpds. R1C triple bond C.CH2X (where R' = a (cyclo)aliphatic, aromatic polycyclic or trialkylsilyl gp. opt. contg. non-metallisable substituents, X = OR, NR2, or PR2, where R is as for R' and may form cyclic tert-amines or - phosphines) are metallised without structural change using an organo-alkali reagent in a solvent at -80 to -30 degrees C, pref. -80 to -50 degree C. These may be reacted with carbonyl cpds. to give the new cpds. R1C=C.CHXC(OH) R3R4 (where R3 and R4 = H or opt. substd. (cyclo) aliphatic, aromatic or alkaryl gps. or a (poly)cyclic gp. (e.g. of a steroid)).

IMPROVED DECARBONYLATION PROCESS FOR FURFURAL WITH A VIEW TO OBTAINING FURANNE AND DECARBONYLATION CATALYST FOR ITS IMPLEMENTATION

LE PROCEDE DE DECARBONYLATION CONFORME A L'INVENTION EST DU TYPE CONSISTANT A CHAUFFER LE FURFURAL EN PRESENCE D'UN CATALYSEUR A BASE DE PALLADIUM DEPOSE SUR UN SUPPORT ET A DISTILLER LE FURANNE FORME; IL EST CARACTERISE EN CE QUE L'ON REALISE PREALABLEMENT UNE IRRADIATION DU CATALYSEUR AU MOYEN D'UN RAYONNEMENT ULTRAVIOLET EN PARTICULIER DE LONGUEUR D'ONDE COMPRISE ENTRE 230 ET 270NANOMETRES. UN SEL DE METAL ALCALIN OU ALCALINO-TERREUX TEL QUE DU CARBONATE DE POTASSIUM PEUT ETRE MELANGE AU CATALYSEUR ET IRRADIE AVEC CELUI-CI POUR AMELIORER ENCORE LES PERFORMANCES DU PROCEDE. THE DECARBONYLATION PROCESS CONFORMING TO THE INVENTION IS OF THE TYPE CONSISTING OF HEATING FURFURAL IN THE PRESENCE OF A PALLADIUM-BASED CATALYST DEPOSITED ON A SUPPORT AND DISTILLING THE FORMED FURANNE; IT IS CHARACTERIZED IN THAT A CATALYST IRRADIATION IS PREVIOUSLY CARRIED OUT BY MEANS OF ULTRAVIOLET RADIATION, IN PARTICULAR WAVELENGTH BETWEEN 230 AND 270 NANOMETERS. AN ALKALINE OR ALKALINE EARTHY METAL SALT SUCH AS POTASSIUM CARBONATE MAY BE MIXED WITH THE CATALYST AND IRRADIATED WITH IT TO ENHANCE THE PROCESS PERFORMANCE.

NEW VEGETABLE OIL COMPOUNDS FOR USE IN THE PHARMACEUTICAL AND COSMETIC INDUSTRY, PARTICULARLY FOR THE INHIBITION OF CELL GROWTH

METHODS OF SELECTIVELY EXTRACTING THE INSAPONIFIABLES OF RAW MATERIALS REACTIVE TRITURING IN THE PRESENCE OF A COSOLVANT

L'invention concerne des procédés d'extraction d'une fraction insaponifiable d'une matière première renouvelable, comprenant la trituration réactive de la matière première déshydratée en présence d'au moins un solvant organique polaire comprenant au moins un alcool léger, d'au moins un cosolvant apolaire non miscible avec ledit alcool léger et d'au moins un catalyseur, conduisant à l'obtention d'une phase organique polaire enrichie en lipides fonctionnalisés par une ou plusieurs fonctions choisies parmi les fonctions hydroxyle, époxyde, cétone, thiol, aldéhyde, éther et amine, et d'une phase organique apolaire enrichie en lipides ne contenant pas ou peu de fonctions hydroxyle, époxyde, cétone, thiol, aldéhyde, éther et amine, puis la concentration des phases organiques.

Patent FR2201036B1

A kind of method that 5 hydroxymethyl furfural add in-place hydrogen prepares 2,5- dimethyl furans

本发明涉及一种5‑羟甲基糠醛原位加氢制备2,5‑二甲基呋喃的方法，将5‑羟甲基糠醛、一级醇和Cu基催化剂混合后，加热升温至150～250℃进行反应，反应时间为0.5～7h，得到2,5‑二甲基呋喃；所述Cu基催化剂为三元催化剂Cu‑ZnO‑CoO x 。该制备方法通过优化制备条件，进一步提高5‑羟甲基糠醛的转化率以及2,5‑二甲基呋喃的选择性。

Process for preparing furan

СПОСОБ ПОЛУЧЕНИЯ ФУРАНА каталитическим окислением 1,3-бутадиена при 75104&amp;deg; С каталитической смесью водного раствора меди со средней валентностью, отвечающей степени окислени  между 1 и 2, и солюбилизирующего агентэ дл  нона одновалентной меди при рН менее 2, отличающийс   тем, что, с целью повышени  конверсии бутадиена, процесс провод т в присутствии 7,5 10 - 0,5 г моль/л иода, вз того в виде элементарного иода или в виде йодсодержащего соеданени , пу  концентрации меди 1 4г . моль/л при соотношении количества ионов двухвалентаой меди к количеству ионов одновалентной меди от 1 :.1 до 4:1 и используют солюбилизируюший агент концентрации 0,03 - О ts 5г- моль/л. (Л

Process for preparing 4-hydroxy-2-cyclopenten-i-ones, 2-methyl-2,5-dimethoxy-2,5-dihydrofurans and a process for their preparation

Furfuryloxycarbonyl fluoride and its use for the synthesis of furfuryloxycarbonyl amino acids

Patent FR2678614B1

The method for producing alkyl furan

本文提供了生产二烷基呋喃(如2,5‑二甲基呋喃)和其他烷基呋喃(如2‑甲基呋喃)的方法。例如，2,5‑二甲基呋喃可以通过在具有过量的碱性或酸性位点(如通过CO2或NH3的化学吸附所测定的)的固体负载金属催化剂的存在下氢化(5‑甲基呋喃‑2‑基)甲醇或2‑(氯甲基)‑5‑甲基呋喃而生产。该方法可以进一步包括脲试剂(TMU、DMPU、TMI)和烷基苯。

Preparation of furan compounds

Furan compounds are prepared by converting bu- tenediols, using a redox system which is an aqueous solution containing copper having an average oxidation state of between 1 and 2, a solubilizing agent for Cu +1 ions, and 0.05-2.00 moles per liter of hydrogen ions.

Preparation of dimethylfurane

A kind of process units and method for preparing 2- methylfurans

本发明属于一种制备2‑甲基呋喃的生产装置及方法；包括氢气气柜，氢气气柜与径向反应器的物料进口相连，液相糠醛计量罐与径向反应器的物料进口相连，径向反应器的物料出口依次通过第一进料预热器的第一介质管束、冷却器管程、2‑甲基呋喃粗品储槽、进料泵、第一进料预热器第二介质管束与第一精馏塔的中下部进口相连，第一精馏塔顶部的气相出口通过第一进料预热器第三介质管束与中间罐的进口端相连，中间罐的第二出口端通过第二进料预热器壳程与第二精馏塔中上部进口相连，第二精馏塔顶部的气相出口通过第二进料预热器管程和冷凝器的管程与成品储槽相连；具有降低床层阻力、提高反应效率、移出床层反应换热、降低扩散阻力的优点。

alkylfuran production methods

são providos aqui métodos de produção de dialquilfuranos, tais como 2,5-dimetilfurano, e outros alquilfuranos, tais como 2-metilfurano. por exemplo, 2,5-dimetilfurano pode ser produzido reduzindo (5-metilfurano-2-il)metanol ou 2-(clorometil)-5-metilfurano. Methods of producing dialkylfurans such as 2,5-dimethylfuran and other alkylfurans such as 2-methylfuran are provided herein. for example 2,5-dimethylfuran may be produced by reducing (5-methylfuran-2-yl) methanol or 2- (chloromethyl) -5-methylfuran.

Preparation of furan compounds

TITLE Preparation of Furan Compounds ABSTRACT Furan compounds are prepared by converting butenediols, using a redox system which is an aqueous solution containing copper having an average oxidation state of between 1 and 2, a solubilizing agent for Cu+1 ions, and 0.05-2.00 moles per liter of hydrogen ions.

Process for the preparation of furans and phenanthrenes

Furans are prepared by reacting a beta , gamma -olefinically unsaturated carbonyl compound, at temperatures of from -20 to +150 DEG C, with an oxidising agent which is suitable for epoxidising or hydroxylating olefinic double bonds. Phenanthrenes are prepared by converting a beta , gamma -olefinically unsaturated carbonyl compound from the group comprising the 2-(cyclohexen-1-yl)cyclohexanones, at temperatures of from -20 to +150 DEG C and using an oxidising agent which is suitable for epoxidising or hydroxylating olefinic double bonds, into the corresponding, partially hydrogenated, dibenzofuran, subsequently reacting the latter with a dienophile, and subjecting the resulting adduct first to a dehydrating treatment and then to a dehydrogenating treatment.

Catalytic process for producing furan derivatives from carbohydrates in a biphasic reactor

Described is a catalytic process for converting sugars to furan derivatives (e.g. 5-hydroxymethylfurfural, furfural, dimethylfuran, etc.) using a biphasic reactor containing a reactive aqueous phase and an organic extracting phase. The process provides a cost-effective route for producing di-substituted furan derivatives. The furan derivatives are useful as value-added intermediates to produce polymers, as precursors to diesel fuel, and as fuel additives.

METHODS OF SELECTIVELY EXTRACTING THE INSAPONIFIABLES OF RAW MATERIALS REACTIVE TRITURING IN THE PRESENCE OF A COSOLVANT

Insecticide composition

Ruthenium iridium catalyst, preparation method thereof and application of ruthenium iridium catalyst in hydrogenolysis reaction of 5-hydroxymethylfurfural

本发明公开了一种钌铱催化剂、其制备方法及在5‑羟甲基糠醛氢解反应中的应用，其中钌铱催化剂载体为活性炭，负载的金属为钌和铱。本发明催化剂在催化反应中不使用任何腐蚀性酸溶液，可以高效、廉价、环保、安全、稳定地转化5‑羟甲基糠醛为2,5‑二甲基呋喃的催化剂，反应物5‑羟甲基糠醛的转化率达到了100％，目标产物2,5‑二甲基呋喃的产率高达97％，副产物只有微量的腐蚀质。