Improved assays to quantify chromatin targets using antibody-targeted enzyme digestion
Номер патента: CA3195344A1
Опубликовано: 05-05-2022
Автор(ы): Andrea L. JOHNSTONE, Ellen WEINZAPFEL, Kelsey NOLL, Martis W. COWLES, Matthew R. MARUNDE, Michael-Christopher KEOGH, Nathan W. HALL, Zu-Wen SUN
Принадлежит: Individual
Опубликовано: 05-05-2022
Автор(ы): Andrea L. JOHNSTONE, Ellen WEINZAPFEL, Kelsey NOLL, Martis W. COWLES, Matthew R. MARUNDE, Michael-Christopher KEOGH, Nathan W. HALL, Zu-Wen SUN
Принадлежит: Individual
Реферат: This present invention relates to methods for improved assays to quantify the level of chromatin targets from biological samples. These assays can be used for the detection of global levels of epigenetic modifications (e.g., histone and DNA modifications), chromatin associated proteins, or chromatin associated ribonucleic acids (RNA). The invention further relates to assay kits that include the reagents needed to prepare biological samples and perform said improved chromatin assays.
Improved assays to quantify chromatin targets using antibody-targeted enzyme digestion
Номер патента: EP4237850A1. Автор: Matthew R. MARUNDE,Nathan W. HALL,Zu-Wen SUN,Martis W. COWLES,Andrea L. JOHNSTONE,Michael-Christopher KEOGH,Ellen WEINZAPFEL,Kelsey NOLL. Владелец: Epicypher Inc. Дата публикации: 2023-09-06.