In vivo transformation of pancreatic acinar cells into insulin-producing cells
Номер патента: NZ575590A
Опубликовано: 30-03-2012
Автор(ы): Paul A Grayburn, Shuyuan Chen
Принадлежит: Baylor Res Inst
Опубликовано: 30-03-2012
Автор(ы): Paul A Grayburn, Shuyuan Chen
Принадлежит: Baylor Res Inst
Реферат: Disclosed is a single construct vector for expressing betacellulin (BTC) and Pancreas Duodenum Homeobox-1 (PDX1) in the manufacture of a medicament for inducing insulin production to treat diabetes. Also disclosed is a composition comprising a microbubble capable of being destroyed upon exposure to ultrasound; and a nucleic acid expression construct that expresses betacellulin, and PDX1 when transfected into acinar cells disposed within the microbubble.
In vivo transformation of pancreatic acinar cells into insulin-producing cells
Номер патента: KR20090079897A. Автор: 폴 에이. 그레이번,슈유안 천. Владелец: 베일러 리서치 인스티튜트. Дата публикации: 2009-07-22.