Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacture of levetiracetam and analogues
Реферат: The present invention relates to an improved process for the preparation of (S)-(-)-alpha-ethyl-2-oxo-1-pyrrolidine acetamide and analogues thereof. The invention also relates to compounds of the general formula (6) wherein R1 is methyl or ethyl; and R2 is C?2#191 -C?4#191 alkyl, C?2#191-C?4#191 alkenyl or C?2#191-C?4#191 alkynyl, optionally substituted by one or more halogen, and their preparation processes.
2-acylpyrrolidines; compounds, preparation and pharmaceutical compositions
Номер патента: NZ276600A. Автор: Shujaath Mehdi,Joseph Paul Burkhart,Norton Paul Peet. Владелец: Merrell Pharma Inc. Дата публикации: 1997-09-22.