Compositions for treating cancer with kras mutations and uses thereof
Номер патента: CA3181170A1
Опубликовано: 28-10-2021
Автор(ы): Gilles Divita, Neil P. Desai
Принадлежит: Aadigen LLC
Опубликовано: 28-10-2021
Автор(ы): Gilles Divita, Neil P. Desai
Принадлежит: Aadigen LLC
Реферат: The present application provides guide RNAs and genome-editing complexes or nanoparticles that are useful for specifically targeting a mutated KRAS. Exemplary genome-editing complexes or nanoparticles comprise cell-penetrating peptides, and optionally a DNA nuclease (such as Cas9) or a polynucleotide encoding the DNA nuclease.
Non-natural nucleic acid ligand, uses thereof, and pharmaceutical composition for preventing or treating cancer comprising same as active ingredient
Номер патента: WO2023014192A1. Автор: 이중환,이종욱,이세나,박한슬. Владелец: 인터올리고 주식회사. Дата публикации: 2023-02-09.