Methods and compositions for assembly of biological nanopores
Номер патента: EP4051778A1
Опубликовано: 07-09-2022
Автор(ы): Cynthia CECH, Robert BUSAM
Принадлежит: Stratos Genomics Inc
Опубликовано: 07-09-2022
Автор(ы): Cynthia CECH, Robert BUSAM
Принадлежит: Stratos Genomics Inc
Реферат: Methods and compositions for the manufacture and use of a detection apparatus based on one or more native biological nanopores are provided. Uses include, but are not limited to, detection and sequencing of nucleic acids. The present invention relates generally to new methods and compositions for making protein-based nanopore sensors, more specifically, to methods of assembling native nanopore proteins in lipid nanodiscs, which are used as carriers to deliver the nanopore to a lipid membrane constituent of a sensor system, and to methods for the utilization thereof, particularly in nanopore-based nucleic acid sequencing methods.
Method and compositions for the detection of protein glycosylation
Номер патента: US09689022B2. Автор: Sabine Arndt,Linda Hsieh-Wilson,Nelly Khidekel,Hwan-Ching Tai. Владелец: California Institute of Technology. Дата публикации: 2017-06-27.