Compounds, compositions, and methods
Номер патента: EP4247376A1
Опубликовано: 27-09-2023
Автор(ы): Alex L. BAGDASARIAN, Anthony A. ESTRADA, Arun Thottumkara, Benjamin J. HUFFMAN, Brian M. Fox, CHENG Hu, Cyril Bucher, II Robert A. CRAIG, Javier De Vicente Fidalgo, Katrina W. LEXA, Lizanne G. NILEWSKI, Maksim OSIPOV
Принадлежит: Denali Therapeutics Inc
Опубликовано: 27-09-2023
Автор(ы): Alex L. BAGDASARIAN, Anthony A. ESTRADA, Arun Thottumkara, Benjamin J. HUFFMAN, Brian M. Fox, CHENG Hu, Cyril Bucher, II Robert A. CRAIG, Javier De Vicente Fidalgo, Katrina W. LEXA, Lizanne G. NILEWSKI, Maksim OSIPOV
Принадлежит: Denali Therapeutics Inc
Реферат: The present disclosure relates generally to small molecule modulators of NLR Family Pyrin Domain Containing 3 (NLRP3), or a pharmaceutically acceptable salt, isotopically enriched analog, stereoisomer, mixture of stereoisomers, or prodrug thereof, methods of making and intermediates thereof, and methods of using thereof.
Tropomyosin receptor kinase (TRK) degradation compounds and methods of use
Номер патента: US12065442B2. Автор: Jing Liu,Liqun Chen. Владелец: Cullgen Shanghai Inc. Дата публикации: 2024-08-20.