Use of liposomes to deliver a protein and a gene encoding the protein to a live cell.

Use of liposomes to deliver a protein and a gene encoding the protein to a live cell

Номер патента: EP3826683A1
Опубликовано: 02-06-2021
Автор(ы): Avinash Seth, Robert D. Fish
Принадлежит: So Young Life Sciences Corp

Реферат: The present invention provides compositions and methods for treating a cancer using liposomes. Collectively, the liposomes contain a protein and a vector encoded for a gene corresponding to the protein. The amount of the protein and the vector in a plurality of liposome is sufficiently effective to treat cancer cells. At least some of the liposomes can contain an antibody that recognizes, and thereby targets, a protein expressed on the cancer cell.

Рисунок 1. Взаимосвязь патентов (ближайшие 20).

Use of liposomes to deliver a protein and a gene encoding the protein to a live cell

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Modified polyamines grafted to a particulate, solid support as sorbent materials for removal of target substances from fluids

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Modified polyamines grafted to a particulate, solid support as sorbent materials for removal of target substances from fluids

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Modified polyamines grafted to a particulate, solid support as sorbent materials for removal of target substances from fluids

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Modified polyamines grafted to a particulate, solid support as sorbent materials for removal of target substances from fluids

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Method for treating a filter and a control method therefore

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Method for operating an electrolyzer and a fuel cell by means of a common converter, apparatus and electrolysis system

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A method for treating a mixture containing an ester compound, a chemical processing equipment, a mixture containing an ester compound, and a composition of ester compounds

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Method of recovering acetone and a plant for recovering the same

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Protein exhibiting activity of pyrethrin biosynthetic enzyme, gene encoding the protein, and vector bearing the gene

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Protein exhibiting activity of pyrethrin biosynthetic enzyme, gene encoding the protein, and vector bearing the gene

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Protein exhibiting activity of pyrethrin biosynthetic enzyme, gene encoding the protein, and vector bearing the gene

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Gene encoding the open reading frame of the m segment of cchf and recombinant structure ensuring expression of structural glycoproteins of the crimean-congo hemorrhagic fever virus

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Plant suitable for increasing production of phloem tissue and use of same

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Triterpene oxidase derived from plant belonging to genus glycyrrhiza, gene encoding the same, and method of using the same

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Triterpene oxidase derived from plant belonging to genus glycyrrhiza, gene encoding the same, and method of using the same

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Therapy delivery and monitoring using a gene of interest-reporter fusion protein and optical imaging

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Use of active cytokinin synthase gene

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Protein having glycoalkaloid biosynthetic enzyme activity and gene encoding the same

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Gene encoding protein with vicinal diketone or diacetyl-reducing activity and use thereof

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Gene encoding protein with vicinal diketone or diacetyl-reducing activity and use thereof

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Genes encoding proteins regulating pH of vacuoles

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Soil microorganism, novel oxidoreductase separated from the soil microorganism, gene encoding the oxidoreductase, and method for producing aglycones using the microorganism, the oxidoreductase and the gene

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Gene encoding lignan methyltransferase and use thereof

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Gene encoding lignan methyltransferase, and use thereof

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Gene, ars-r anchorage cassette, ars-r expression- anchorage cassette, recombinant plasmid, bacterial transgenic lineage, use of said gene, use of said lineage in environmental bioremediation processes

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Gene, ars-r anchorage cassette, ars-r expression- anchorage cassette, recombinant plasmid, bacterial transgenic lineage, use of said gene, use of said lineage in environmental bioremediation processes

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Proteins relating to grain shape and leaf shape of rice, genes coding said proteins and uses thereof

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Use of the green fluorescent protein as a screenable marker for plant transformation

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Malus Domestica 4-Coumaric Acid: Coenzyme A Ligase 4 Gene and Encoded Protein and Application Thereof

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Mutant Plk protein and gene encoding the same

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Mutant Plk protein and gene encoding the same

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Mutant Plk protein and gene encoding the same

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A gene encoding cyclododecanone monooxygenase

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A gene encoding cyclododecanone monooxygenase

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A gene encoding cyclododecanone monooxygenase

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A genetically engineered bacterium and a preparation method and use thereof

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Gene encoding acetolactate synthase

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Gene cluster of vicenistatin biosynthesis, a vicenisamine glycosyltransferase polypeptide, and a gene encoding the polypeptide

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Methods for isolating and culturing living cells using method of permeabilizing cell membrane

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Methods for isolating and culturing living cells using method of permeabilizing cell membrane

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Penicillin G acylase, a gene encoding the same and a method for the production of this enzyme

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Genes encoding open reading frames of m and l-segments of cchf, and recombinant constructs that provide expression of structural glycoproteins and rna-dependent rna polymerase (l) of crimean-congo hemorrhagic fever virus

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Recombinant microorganism and a method for itaconic acid production

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Precursor polypeptide of phytosulfokine derived from Arabidopsis thaliana and a gene encoding said polypeptide

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DNA sequences capable of expressing foreign proteins and metabolites in dicotyledonous plants and cell culture

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Gene encoding a protein having an ability to enhance a selenate reduction activity

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Protein and peptide delivery systems and methods for making and using them

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New hydrogenase seq id no:5 purified from thermococcus onnurienus na1 with help of carbon monoxide, genes coding it, and methods for producing hydrogen with use of microorganism having said genes

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Novel (r)-2-hydroxy-3-phenylpropionate (d-phenyllactate) dehydrogenase and gene encoding the same

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Protein having glycoalkaloid biosynthetic enzyme activity and gene encoding the same

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Polyhydroxyalkanoate synthase and gene encoding the same

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Inducible expression system for plasmid-free production of a protein of interest

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Inducible expression system for plasmid-free production of a protein of interest

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Gene encoding an alpha-hydroxy-gamma-carboxymuconic acid-epsilon-semialdehyde dehydrogenase

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Protein with activity of hydrolyzing amylopectin, starch, glycogen and amylose, gene encoding the same, cell expressing the same, and production method thereof

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Novel glyphosate-tolerant 5-enolpyruvylshikimate-3-phosphate synthase and the gene encoding the same

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Use of a class of enzymes and their encoding genes to increase the oil content in transgenic organisms

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Method of producing target virus or target proteins different from adenovirus, expression cell and host cell and production methods thereof, use of expression cell

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A genetically engineered bacterium and a preparation method and use thereof

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Method for inducing artificial ageing in a stem cell and uses of said cell

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Use of constitutively active variants of growth factor receptors as selection markers for the generation of stable producer cell lines

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Method for delivery of proteins to plant cells

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Gene encoding enzyme that oxidizes position 16 of steroid skeleton and plant in which expression level of the gene is lowered

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Method for delivery of proteins to plant cells

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Use of a class of genes encoding lysophospholipid acyl transferases for application in agriculture, biotechnology, and medicine

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Novel (r)-2-hydroxy-3-phenylpropionic acid (d-phenyllactic acid) dehydrogenase and gene encoding the same

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Escherichia coli expressing the cytochrome p-450 gene and a method for microbial conversion using them

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β-galactoside-α2,3-sialyltransferase, a gene encoding thereof, and a method for producing thereof

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Modification of plant development and plant cell differentiation by use of the deac system

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Method of qualitative and quantitative estimation of fixation of membrane protein and ligand

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Cellular microarray and using thereof in living cell investigations

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A method for providing resistance to a plant or plant cell comprising modifying a gene or modifying expression of a NDR/NHL protein gene in a plant

Номер патента: NZ550620A. Автор: Eduard Daniel Leendert Schmidt. Владелец: Expressive Res Bv. Дата публикации: 2008-05-30.

PROTOCOL ACCELERATOR MODULE WITH PACKET FORWARDING FUNCTION AND A METHOD OF TRANSCEIVER OPERATION FOR RAPID FORWARDING OF DATA PACKETS

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Production method for protein and carbohydrate food product

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Use of liposomes to deliver a protein and a gene encoding the protein to a live cell

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