Nucleic acids for inhibiting expression of complement factor b (cfb) in a cell
Номер патента: EP4396346A1
Опубликовано: 10-07-2024
Автор(ы): Eliot MORRISON, Sibylle DAMES, Stefan RATHJEN, Steffen Schubert, Timo JOHANNSSEN, Verena Aumiller
Принадлежит: Silence Therapeutics GMBH
Опубликовано: 10-07-2024
Автор(ы): Eliot MORRISON, Sibylle DAMES, Stefan RATHJEN, Steffen Schubert, Timo JOHANNSSEN, Verena Aumiller
Принадлежит: Silence Therapeutics GMBH
Реферат: The invention relates to nucleic acid products that interfere with complement factor B (CFB) gene expression or inhibit its expression. The nucleic acids are preferably for use in the prophylaxis or treatment of complement associated diseases, disorders or syndromes, particularly C3 glomerulopathy (C3G), paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), lupus nephritis, IgA nephropathy (IgA N), myasthenia gravis (MG), and primary membranous nephropathy.
Nucleic acids for inhibiting expression of complement factor b (cfb) in a cell
Номер патента: CA3230589A1. Автор: Sibylle DAMES,Steffen Schubert,Verena Aumiller,Eliot MORRISON,Stefan RATHJEN,Timo JOHANSSEN. Владелец: Silence Therapeutics GMBH. Дата публикации: 2023-03-09.