Genetic immunization with co-delivery of nucleic acid and cytokines in a single vehicle
Номер патента: EP1045699A1
Опубликовано: 25-10-2000
Автор(ы): J. Thomas The Johns Hopkins University AUGUST, Kam W. The Johns Hopkins University LEONG, Vu The Johns Hopkins University TRUONG
Принадлежит: JOHNS HOPKINS UNIVERSITY
Опубликовано: 25-10-2000
Автор(ы): J. Thomas The Johns Hopkins University AUGUST, Kam W. The Johns Hopkins University LEONG, Vu The Johns Hopkins University TRUONG
Принадлежит: JOHNS HOPKINS UNIVERSITY
Реферат: Coacervates of nucleic acids and a polycationic biopolymer are useful for delivery of genes encoding antigens to mammals. The expression of the antigens in the mammal induces an immune response to the antigen. Furthermore, encapsulation of either or both of the antigen protein and a cytokine enhance the immune response. Selection of cytokines can be used to manipulate the type of immune response which is induced.
Genetic immunization with co-delivery of nucleic acid and cytokines in a single vehicle
Номер патента: AU2117299A. Автор: Kam W Leong,J. Thomas August,Vu Truong. Владелец: JOHNS HOPKINS UNIVERSITY. Дата публикации: 1999-08-02.