Non-toxic amounts of protein-aggregating substances stimulate hsp70 expression and function as anti-tumor agents
Номер патента: WO2003086383A8
Опубликовано: 12-02-2004
Автор(ы): Gabriele Multhoff
Принадлежит: Gabriele Multhoff
Опубликовано: 12-02-2004
Автор(ы): Gabriele Multhoff
Принадлежит: Gabriele Multhoff
Реферат: The present invention relates to the use of a drug inducing intracellular protein aggregation for the preparation of a pharmaceutical composition wherein the drug is in a dose of 135-175 mg/m2 body surface for the treatment of a tumor, a bacterial infection or a viral infection. Preferably said drug is selected from vincristine and paclitaxel. The present invention further relates to a method, of treating a patient suffering from a tumor, a bacterial infection or a viral infection comprising administering to said patient a drug inducing intracellular protein aggregation in a dose of 135-175 mg/m2 body surface. It is preferred that said drug is administered in combination with heat treatment.
Non-toxic amounts of protein-aggregating substances stimulate hsp70 expression and function as anti-tumor agents
Номер патента: WO2003086383A1. Автор: Gabriele Multhoff. Владелец: Multimmune GmbH. Дата публикации: 2003-10-23.