15-09-2015 дата публикации
Номер: KR1020150104482A
Автор:
CHOI, KYUNG MIN,
CHA, JEONG DAN,
HWANG, SEUNG MI,
LIM, JI YE,
KANG, JEA RAN,
HAN, SU BEOM
Принадлежит:
The present invention relates to a composition for preventing, alleviating, or treating an oral squamous cell cancer, containing a processed red ginseng extract as an active ingredient and, more specifically, to a composition for preventing, alleviating, or treating an oral squamous cell cancer, containing a processed red ginseng extract, extracted by using methanol, as an active ingredient. The composition according to the present invention has the effects of: killing an HSC-3 cell; promoting the expression of Caspase -3, -8, and -9 of the HSC-3 cell; promoting the expression of segmental PARP of the HSC-3 cell; inducing a period of the HSC-3 to proceed to a cell self-destruction period; inhibiting the expression of Bcl-2 of the HSC-3 cell; promoting the expression of pro-apoptosis protein containing Bad, Bim, and Bax of the HSC-3 cell; and promoting the expression of MAPK passage protein containing ERK, pERK, JNK, pJNK, p38, and pp38. COPYRIGHT KIPO 2015 ...
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