20-01-2022 дата публикации
Номер: US20220018831A1
Принадлежит:
The disclosure relates to a method for eliminating interference of theophylline in immunoassay and an immunodetection kit. The method for eliminating interference of theophylline in immunoassay includes: performing an immunoassay in the presence of a theophylline interference-resistant agent, the theophylline interference-resistant agent having a final concentration of 0.1 mg/mL-100 mg/mL, and being selected as at least one component from a group consisting of free 6-mercaptopurine, 6-thioguanine, 8-azguanine, hypoxanthine, adenine, purine, 2,6,8-trioxypurine, adenine nucleotide, and adenosine. The method and the kit can effectively reduce interference of theophylline on immunoassay results. 115-. (canceled)16. An immunoassay method , comprising:providing a blood sample;providing an immunoassay kit, wherein the immunoassay kit comprises a substrate, a labeling substance, and a solid phase coated with an immunoassay reactant, wherein at least one of the substrate, the labeling substance and the solid phase comprises a theophylline interference-resistant agent, and the theophylline interference-resistant agent comprises at least one component selected from the group consisting of 6-mercaptopurine, 6-thioguanine, 8-azaguanine, hypoxanthine, adenine, purine, 2,6,8-trioxypurine, adenine nucleotide and adenosine;performing an immunoassay of the blood sample by using the immunoassay kit, wherein the theophylline interference-resistant agent has a final concentration of 10 mg/mL to 100 mg/mL and is used to eliminate interference of theophylline in the immunoassay of the blood sample.17. The immunoassay method of claim 16 , wherein the final concentration of the theophylline interference-resistant agent is in a range of 20 mg/mL to 80 mg/m L.18. The immunoassay method of claim 16 , wherein the theophylline interference-resistant agent comprises at least one component selected from the group consisting of 6-mercaptopurine claim 16 , adenine claim 16 , 2 claim 16 ,6 claim 16 , ...
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