30-04-2020 дата публикации
Номер: US20200129431A1
Принадлежит:
A lipid membrane structure includes, as lipid components, a lipid compound represented by Formula (I): 1. A lipid compound represented by Formula (I) or a salt thereof ,{'br': None, 'sup': 1', '2, 'sub': 2', 'a', 'b, '(R)(R)C(OH)—(CH)—(O—CO)—X\u2003\u2003(I)'}{'sup': 1', '2, 'claim-text': {'br': None, 'sub': 3', '2', 'q', 'r', '2', 's', 't', '2', 'u', 'c', '2', 'v, 'CH—(CH)—(CH═CH)—(CH)—(CH═CH)—(CH)—(CO—O)—(CH)—\u2003\u2003(A)'}, '[in the formula, a represents an integer of 3 to 5; b represents an integer of 0 or 1; and Rand Reach independently represents a group represented by Formula (A){'sub': b', '1-4', '2-4, 'claim-text': {'br': None, 'sub': '2', 'i': 'd', 'sup': 3', '4, '—(CH)-N(R)(R)\u2003\u2003(B)'}, '(in the formula, q represents an integer of 1 to 9; r represents 0 or 1; s represents an integer of 1 to 3; t represents 0 or 1; u represents an integer of 1 to 8; c represents 0 or 1; and v represents an integer of 4 to 12, where, a case in which q is an integer of 3 to 5, r and t are 1, s is 1, and u+v is an integer of 6 to 10 is excluded in a case where both b and c are 0); and X represents a 5- to 7-membered non-aromatic heterocyclic group (where, the group is bonded to (O—CO)— by a carbon atom, and one or two Calkyl groups or Calkenyl groups may be substituted on the ring), or X represents a group represented by Formula (B){'sup': 3', '4', '3', '4, 'sub': 1-4', '2-4', '1-4', '2-4', '1-4', '2-4, '(in the formula, d represents an integer of 0 to 3, and Rand Reach independently represents a Calkyl group or a Calkenyl group (where, the Calkyl group or Calkenyl group may be substituted by one or two phenyl groups), but Rand Rmay be bonded to each other to form a 5- to 7-membered non-aromatic heterocycle (where, one or two Calkyl groups or Calkenyl groups may be substituted on the ring)].'}2. The lipid compound or a salt thereof according to claim 1 , wherein r and t are 0 claim 1 , and q+s+u is an integer of 8 to 18 and is preferably an integer of 10 to 16.3. ...
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