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  • Differentially expressed genes involved in cancer, the polypeptides encoded thereby, and methods of using the same

Differentially expressed genes involved in cancer, the polypeptides encoded thereby, and methods of using the same

Номер патента: EP1560597A2
Опубликовано: 10-08-2005
Автор(ы): Barbara K. Pfizer Global Research and KLEIN, Jia-Ying J. Pfizer Global Research and BU, Maureen J. Pfizer Global Research and BOURNER, Nicholas R. Pfizer Global Research and STATEN, Paul J. Pfizer Global Research and HIPPENMEYER, Richard A. Pfizer Global Research and MAZZARELLA, Richard D. Pfizer Global Research and HEAD
Принадлежит: Pharmacia LLC

Реферат: The invention relates nucleic acids and their encoded polypeptides, whose expression is modulated in cancer or tumor cells. The invention further relates to methods useful for treating or modulating cancer or tumors in mammals in need of such biological effect. This includes the diagnosis and treatment of oncological disorders. Additionally, the present invention further relates to the use of antibodies against the polypeptides of the present invention as diagnostic probes or as therapeutic agents as well as the use of polynucleotide sequences encoding the polypeptides of the present invention as diagnostic probes or therapeutic agents for the treatment of a broad range of pathological states.

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Yeast cell with activated lactate dehydrogenase and method of producing lactate using the yeast cell

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