COMBINATION OF A LIGAND OF HVEM AND AN IMMUNOTOXIN FOR USE IN THERAPY.

COMBINATION OF A LIGAND OF HVEM AND AN IMMUNOTOXIN FOR USE IN THERAPY

Номер патента: US20160151489A1
Опубликовано: 02-06-2016
Автор(ы): Olive Daniel, Pasero Christine
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Рисунок 1. Взаимосвязь патентов (ближайшие 20).

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Peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (RCC) and other cancers

Номер патента: US12005105B2. Автор: Harpreet Singh,Toni Weinschenk,Andrea MAHR,Oliver Schoor,Jens FRITSCHE,Colette Song. Владелец: IMMATICS BIOTECHNOLOGIES GMBH. Дата публикации: 2024-06-11.

Combination therapy of a pd-1 antagonist, a lag3 antagonist and an antibody drug conjugate that binds 191p4d12 protein for treating patients with cancer

Номер патента: WO2024129552A3. Автор: Jane Anne HEALY,Blanca Homet Moreno,Eric H. Rubin. Владелец: Merck Sharp & Dohme LLC. Дата публикации: 2024-07-25.

Peptidomimetics and their use in therapy

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Novel peptides and combination of peptides for use in immunotherapy against aml and other cancers

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Peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (RCC) and other cancers

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Peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers

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Conjugate of a single domain antibody, a saponin and an effector molecule, pharmaceutical composition comprising the same, therapeutic use of said pharmaceutical composition

Номер патента: EP4452325A1. Автор: Guy Hermans,Ruben POSTEL. Владелец: Sapreme Technologies BV. Дата публикации: 2024-10-30.

Peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers

Номер патента: US12065477B2. Автор: Philipp Wagner,Heiko Schuster,Hans-Georg Rammensee,Janet PEPER,Kevin Roehle. Владелец: IMMATICS BIOTECHNOLOGIES GMBH. Дата публикации: 2024-08-20.

Peptides and combination of peptides as targets or active ingredients for use in immunotherapy against AML and other cancers

Номер патента: US12036271B2. Автор: Harpreet Singh,Toni Weinschenk,Andrea MAHR,Oliver Schoor,Jens FRITSCHE,Anita WIEBE. Владелец: IMMATICS BIOTECHNOLOGIES GMBH. Дата публикации: 2024-07-16.

Mutant selectivity and combinations of a phosphoinositide-3-kinase inhibitor compound and chemotherapeutic agents for the treatment of cancer

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Compositions and libraries containing recombinant polynucleotides encoding t-cell receptors and methods for using recombinant t-cell receptors

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Novel combination based on rifaximin and probiotic yeasts, compositions containing it and their use in therapy

Номер патента: WO2024116060A1. Автор: Angelo Pizzoni,Paolo PIZZONI. Владелец: Nyuma Pharma Srl. Дата публикации: 2024-06-06.

Deoxy-cytidine or uridine derivatives for use in cancer therapies

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Deoxy- cytidine derivatives for use in cancer therapies

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Deoxy- cytidine or uridine derivatives for use in cancer therapies

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Niclosamide and its derivatives for use in the treatment of solid tumors

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Novel mettl3 inhibitors and use thereof in therapy

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Pharmaceutical combinations for use in the treatment of neoplastic diseases.

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Combination of gold complexes with olaparib or other parp1/2 inhibitors for use in the treatment of cancer resistant to said parp1/2 inhibitors

Номер патента: CA3118820A1. Автор: James Harrison,Melinda DUER,Uliana BASHTANOVA. Владелец: Varsity Pharmaceuticals Ltd. Дата публикации: 2021-04-01.

Combination of gold complexes with olaparib or other parp1/2 inhibitors for use in the treatment of cancer resistant to said parp1/2 inhibitors

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Peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (RCC) and other cancers

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Peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (RCC) and other cancers

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COMBINATION OF (A) PHOSPHOINOSITIDE-3-KINASE INHIBITOR AND (B) Ras/Raf/Mek PATHAWAY MODULATOR

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Compounds for use in cancer therapy

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Barbiturate and thiobarbiturate compounds for use in cancer therapy

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Isoquinoline derivatives for use in therapy

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Isoquinoline derivatives for use in therapy

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Specific TT virus sequences and chimeric TT virus host cell DNA molecules for use in diagnosis, prevention and treatment of cancer and autoimmunity

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Process for the preparation of a 15-deoxy-16-oxygenated prostanoic acid secretion and for a prostanoic acid derivative suitable for use in this process.

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Phosphate prodrugs of a farnesyl dibenzodiazepinone, processes for their production and their use as pharmaceuticals

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Phosphate prodrugs of a farnesyl dibenzodiazepinone, processes for their production and their use as pharmaceuticals

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Additive for use in any energy supplementation, use of a protein hydrolysate to the preparation of energy supplementaton and an energy supplement containing such an additive

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Uniport having a one-piece body anchor and an elongated surgical instrument passageway for use in single site surgical procedures

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Rotating unit of a medical imaging device with a hydrostatic slide bearing and an integrated coolant conduit

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Rotating unit of a medical imaging device with a hydrostatic slide bearing and an integrated coolant conduit

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GENE-THERAPEUTIC DNA-VECTOR BASED ON THE GENE-THERAPEUTIC DNA-VECTOR VTvaf17, CARRYING THE TARGET GENE SELECTED FROM THE GROUP OF GENES COL1A1, COL1A2, BMP2, BMP7, TO INCREASE THE LEVEL OF EXPRESSION OF THESE TARGET GENES, METHOD FOR PRODUCTION AND USE THEREOF, ESCHERICHIA COLI SCS110-AF/VTvaf17-COL1A1 STRAIN OR ESCHERICHIA COLI SCS110-AF/VTvaf17-COL1A2 OR ESCHERICHIA COLI SCS110-AF/VTvaf17-BMP2 OR ESCHERICHIA COLI SCS110-AF/VTvaf17-BMP7, CARRYING A GENE-THERAPEUTIC DNA VECTOR, METHOD FOR PRODUCTION THEREOF, A METHOD FOR INDUSTRIAL PRODUCTION OF A GENE-THERAPEUTIC DNA-VECTOR

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Trispecific binding molecules, which specifically bind antigens of a variety of malignant tumors, and methods of using them

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Delivery, use and use in therapy of crispr-cas systems and compositions for targeted action on disorders and diseases using viral components

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Interferon-associated antigen binding proteins for use for the treatment or prevention of hepatitis delta virus infection

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Novel peptides and combination of peptides for use in immunotherapy against various tumors

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Multiplex biomarker for use in evaluation of state of accumulation of amyloid b in brain, and analysis method for said evaluation

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Peptides and combination of peptides for use in immunotherapy against various tumors

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Cd8+ regulatory t-cells for use in the treatment of inflammatory and autoimmune diseases

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Method for the identification of cd4+ regulatory t-cells for use in the treatment of inflammatory and autoimmune diseases

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Method for the identification of cd4+ regulatory t-cells for use in the treatment of inflammatory and autoimmune diseases

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Products for therapy of a musculoskeletal condition and methods for their production

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Products for therapy of a musculoskeletal condition and methods for their production

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Combination of anti-clusterin oligonucleotide with Hsp90 inhibitor for the treatment of prostate cancer

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Stem cell compositions and methods of producing stem cells for use in therapy

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Discernible cell surface protein variants of cd45 for use in cell therapy

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Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers

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Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers

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Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers

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Discernible cell surface protein variants of cd45 for use in cell therapy

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Antibodies recognising epitope on cd43 and cea expressed on malignant cells and methods for using them

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Peptides and combination of peptides for use in immunotherapy against various tumors

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Novel peptides and combination of peptides for use in immunotherapy against various tumors

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Peptides and combination of peptides for use in immunotherapy against leukemias and other cancers

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Novel peptides and combination of peptides for use in immunotherapy against esophageal cancer and other cancers

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Peptides and combinations of peptides for use in immunotherapy against hematologic neoplasms and other cancers

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Novel peptides and combination of peptides for use in immunotherapy against cll and other cancers

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Peptides and combination of peptides for use in immunotherapy against non-small cell lung cancer and other cancers

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Novel peptides and combination of peptides for use in immunotherapy against epithelial ovarian cancer and other cancers

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Novel peptides and combination of peptides for use in immunotherapy against lung cancer, including nsclc, sclc and other cancers

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Novel peptides and combination of peptides for use in immunotherapy against lung cancer, including nsclc, sclc and other cancers

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Peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers

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Peptides, combination of peptides, and cell based medicaments for use in immunotherapy against urinary bladder cancer and other cancers

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Peptides and combination of peptides for use in immunotherapy against epithelial ovarian cancer and other cancers

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Peptides and combination of peptides for use in immunotherapy against various tumors

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Peptides and combination of peptides for use in immunotherapy against various tumors

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Peptides and combination of peptides for use in immunotherapy against various tumors

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Identification and selection of a plant starting material of a plant chondroitin sulfate and hyaluronic acid, and transformation of such plant starting material to obtain ingredients for use in foods, supplements, medical devices or drugs

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Aptamers for use in the treatment of coronaviridae infections

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Use of a combination of levosimendan and an sglt-2 inhibitor to treat heart failure

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Phosphorylated materials as contrast agents for use in magnetic resonance imaging of the gastrointestinal region

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Cosmetic use of a combination of plant extracts

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Combination of roginolisib and hdac inhibitor in the treatment of haematological malignancy

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Combination of roginolisib and bcl-2 inhibitor in the treatment of haematological malignancy

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Use of a combination of levosimendan and an sglt-2 inhibitor to treat heart failure

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Dosage forms for administering combinations of drugs

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Pharmaceutical combinations for use in the treatment of neoplastic diseases

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Gold particle for use in therapy to prevent or reduce the formation of biofilm in patients who are to receive, are receiving, or have received soft tissue filler

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Combination comprising zd6474 and an antiandrogen

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Combination comprising zd6474 and an antiandrogen

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Pharmaceutical combinations for use in the treatment of neoplastic diseases

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The use of a dna damaging agent and a ligand for the treatment of cancer

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Gold Particle for Use in Therapy to Prevent Scar Formation

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Gold particle for use in therapy to prevent or reduce the formation of biofilm in patients who are to receive, are receiving, or have received soft tissue filler

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Gold Particle for Use in Therapy to Prevent Scar Formation

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Composition comprising a combination of hepatocytes and mesenchymal stromal cells

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Composition comprising sodium hyaluronate and am inoacids for use in the orthopedic filed

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Compositions comprising a combination of creatine and oleuropein or a metabolite thereof and their use for improving muscle function

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Compositions comprising a combination of caffeine and oleuropein or a metabolite thereof and their use for improving muscle function

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Method and composition for use in preparation of a patient for surgery

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Combination Therapy for Use in Treating Retroviral Infections

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Use of dipyridamole, acetylsalicylic acid and an angiotensin II antagonist for treatment and prevention of vascular events

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Methods of treating hypertension with a combination of an aldosterone synthase inhibitor and a diuretic

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Conjugate of a single domain antibody, a saponin and an effector molecule, pharmaceutical composition comprising the same, therapeutic use of said pharmaceutical composition

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Combination comprising zd6474 and an antiandrogen

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A formulation, e.g. for use in the treatment of flu and colds

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Novel formulation for use in pain management

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Methods of treating hypertension with a combination of an aldosterone synthase inhibitor and a diuretic

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Combination of acetylcholinesterase inhibitor and 5-ht4 receptor agonist as neuroprotective agent in the treatment of neurodegenerative diseases

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Interferons and nuclear export inhibitors for use in methods of treating cancer

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Combination therapies comprising a sos1 inhibitor and an egfr inhibitor

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Cosmetic composition for use in increasing the collagen synthesis in skin cells

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Combination of mirtazapine and tizanidine for use in pain disorders

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Combination of ferroquine and an artemisinin derivative for the treatment of malaria

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Curable composition for use in a process of treating a dental situation in the mouth of a patient

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Combination of cannabidiol and alpha-lipoic acid for use in the treatment of ptsd

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Method of Selecting Kind of Size of a Helmet and Shape of a Pad, Method of Adjusting Helmet Size by Using the Selection Method, and Head Size Measuring Tool Used in Aforesaid Selection Method

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Method of selecting size of a helmet and shape of a pad, method of adjusting helmet size by using the selection method, and head size measuring tool used in aforesaid selection method

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Method for Cultivating a Vegetable worms Having a Function of a Natural Preserved Agent and a Freshness Keeping Agent and an Extract from the Same and a Natural Complex Composition From the Same

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Sanitary bag holder and combination of bag and holder

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Ophthalmic interface apparatus, method of interfacing a surgical laser with an eye, and support ring for use with a suction ring

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Durable underwear adapted for use with absorbent component

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Durable underwear adapted for use with absorbent component

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Durable underwear adapted for use with absorbent component

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Durable underwear adapted for use with absorbent component

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Felt material for use in a method of repairing or augmenting human or animal soft tissues

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Combination of ire and rf ablation using a sinusoidal signal generator

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User interface system for use with multipolar pacing leads

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An enema nozzle comprising retention means, and an enema system comprising said enema nozzle

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Method for prediction of a vascular pathology of a posterior segment of an eye in women after suffering preeclampsia

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Container for an Inhalation Device with at Least One Liquid Jet Device, Combination of at Least Two Containers and Method of Conveying Liquid to an Inhalation Device

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2D/3D registration of a digital mouse atlas with X-ray projection images and optical camera photos

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Method and device for extracorporeal life support of a premature fetus

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Combination of underwear and an absorbent pad

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Method for creating flexible arch model of teeth for use in restorative dentistry

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Monitoring of plurality of joints using combination of built-in sensors and external sensor

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Method of preparing an image for use in production of a knee brace and a tibial contour gauge and an image alignment guide for use in said method

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Filter apparatus for use in an automated system for the preparation of a sample for a chemical or composition analysis

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Method of preparing an image for use in production of a knee brace and a tibial contour gauge and an image alignment guide for use in said method

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Device, system and method for determining vital sign information of a subject

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Air disinfection apparatus for use in air conditioning systems

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Methods and systems for use in determination of a patient's heart condition

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Air disinfection apparatus for use in air conditioning systems

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Treated biochar for use in water treatment systems

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A Method for Cultivating a Vegetable worms Having a Function of a Natural Preserved Agent and a Freshness Keeping Agent and an Extract of a Vegetable Worms Cordycepin from the Same and a Natural Complex Composition

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Electroplating bath for depositing a black alloy, method for the electrochemical deposition of a black alloy on a substrate, a black alloy and an article coated with such black alloy

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Method for locally deforming a flat surface of a substrate made of glass or a glass ceramic, and an operating element produced with said method

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Cushioned rubber floor article for use in hair styling salons and other service environments

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Apparatus and method for controlling and stabilizing the swing mechanics of a golfer

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Arrangement for attaching panels to support structures, a construction support structure and fastening means, and their use in modular building elements

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Apparatus for an improved electric fence wire construction for use with intensive grazing

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Ball Joint Base and Twist Lock for Slideable Concentric Members Adapted for Use in Umbrellas with Extensible Canopy Ribs

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Selective adjustment of a defined hardness, firmness and/or ductility of press-hardened and/or hot formed sheet metal components useful in production of vehicle bodies, by covering and/or shielding defined areas/partial areas of components

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Catalyst for Asymmetric Synthesis, Ligand for Use Therein, and Process for Producing Optically Active Compound through Asymmetric Synthesis Reaction Using Them

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Organic electroluminescence device comprising an azine compound and a rare earth metal, rare earth metal compound, and/or rare earth metal complex and an electronic equipment comprising said organic electroluminescence device

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User interface to select field of view of a camera in a smart glass

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Optical device for use with downhole equipment

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Authentication Tokens For Use In Voice Over Internet Protocol Methods

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Method for determining the differentiation state of a stem cell

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Method for determining the differentiation state of a stem cell

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Conductive gasket for use with spring-biased contacts

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Handover processing method, and access point and mobile terminal for use in the method

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Method and system for selecting antennas for communication between a receiver side and a transmitter side of a wireless mimo system

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Fault Detection of a Printed Dot-Pattern Bitmap

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User interface to select field of view of a camera in smart glasses

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Method of forming optical images, an array of converging elements and an array of light valves for use in this method, apparatus for carrying out this method and a process for manufacturing a device using this method

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Assembly of a melting fuse with knife blade contacts and an electric measuring apparatus, as well as a melting fuse suitable for use in such an assembly

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Assembly of a melting fuse with knife blade contacts and an electric measuring apparatus, as well as a melting fuse suitable for use in such an assembly

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Beads for use in reactions for the amplification and/or synthesis of a polynucleotide, and a device and a method for the production thereof

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A method for using a contents software

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Method of reflection removal based on a generative adversarial network used for training of an adas camera of a vehicle

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Method of reflection removal based on a Generative Adversarial Network used for training of an ADAS camera of a vehicle

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Link quality determination of a transmission link in an ofdm transmission system

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Arrangement for monitoring the condition of a power semiconductor module of an electric drive device

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Apparatuses, devices, methods and computer programs for a worker node and an edge server

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Arrangement For Monitoring the Condition of a Power Semiconductor Module of an Electric Drive Device

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Sealing element for sealing a transition between a spray gun body and an attachment of a spray gun, attachment, in particular a paint nozzle arrangement for a spray gun and a spray gun, in particular a paint spray gun

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Semiconductor device having a structure that prevents defects due to precision, bending and the like of a mask without increasing manufacturing steps

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Optimizing timing of display of a video overlay

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Optimizing timing of display of a video overlay

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Identifying memory of a blade device for use by an operating system of a partition including the blade device

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WELL TEMPLATE AND METHOD FOR USE THEREOF

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BIDIRECTIONAL INVERTER FOR CONVERSION BETWEEN A DIRECT CURRENT SOURCE AND AN ALTERNATING CURRENT GRID

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METHOD AND SYSTEM FOR USE IN A CONNECTED STATE HANDOFF OF AN ACCESS TERMINAL

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Control of an Expanded Drying Section of a Paper Machine

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A New or Improved Vacuum Tube or Apparatus for the Production of Violet or Ultra Violet Rays X-rays or other Rays or Combination of Rays by Induction on Low Tension Currents.

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Improvements relating to assistants for use in the textile, leather, paper and like industries

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Improvements in or connected with Lamps particularly applicable for use on Road Vehicles.

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Spectacle frame combination of a primary lenses frame and an auxiliary lenses frame magnetically and provotably attached thereto

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Vanes of a shutter for architectural openings

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Water base drilling mud composition comprising zinc sulfate and an alkaline earth metal oxide or hydroxide

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